Name: Name:(S)-2-(tert-Butoxycarbonylamino)-3-(tert-butyldiphenylsilyloxy)propanoic acid
Brand: AABLOCKS
SKU: AA001DBH
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA001DBH

Chemical Name: (S)-2-(tert-Butoxycarbonylamino)-3-(tert-butyldiphenylsilyloxy)propanoic acid

CAS Number: 145790-51-8

Molecular Formula: C24H33NO5Si

Molecular Weight: 443.6080

MDL Number: MFCD08703135

SMILES: OC(=O)[C@@H](NC(=O)OC(C)(C)C)CO[Si](C(C)(C)C)(c1ccccc1)c1ccccc1

Properties

Complexity: 580

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 1

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 31

Hydrogen Bond Acceptor Count: 5

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 10

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

Downstream Synthesis Route

145790-48-3

145790-51-8

[1]Davies,JohnS.;Higginbotham,ClementL.;Tremeer,E.John;Brown,Charles;Treadgold,RichardC.[JournaloftheChemicalSociety.PerkintransactionsI,1992,#22,p.3043-3048]

50-00-0

145790-51-8

(S)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-5-oxo-oxazolidine-3-carboxylicacidtert-butylester

[1]Reddy,G.Vidyasagar;Rao,G.Venkat;Iyengar[TetrahedronLetters,1998,vol.39,#14,p.1985-1986]

764-43-2

145790-51-8

702702-09-8

[1]Burtoloso,AntonioCarlosB.;Correia,CarlosRoqueD.[TetrahedronLetters,2004,vol.45,#17,p.3355-3358]

3262-72-4

58479-61-1

145790-51-8

[1]Burtoloso,AntonioCarlosB.;Correia,CarlosRoqueD.[JournalofOrganometallicChemistry,2005,vol.690,#24-25,p.5636-5646]

[2]Burtoloso,AntonioCarlosB.;Correia,CarlosRoqueD.[TetrahedronLetters,2004,vol.45,#17,p.3355-3358]

[3]CurrentPatentAssignee:MERCK&COINC-WO2006/4880,2006,A2Locationinpatent:Page/Pagecolumn66

[4]Anderson,JamesC.;GairFord;Whiting,Matthew[OrganicandBiomolecularChemistry,2005,vol.3,#20,p.3734-3748]

[5]Delgado,Oscar;MartinMueller;Bach,Thorsten[Chemistry-AEuropeanJournal,2008,vol.14,#8,p.2322-2339]

[6]Locationinpatent:schemeortableJosien,Hubert;Bara,Thomas;Rajagopalan,Murali;Clader,JohnW.;Greenlee,WilliamJ.;Favreau,Leonard;Hyde,LynnA.;Nomeir,AminA.;Parker,EricM.;Song,Lixin;Zhang,Lili;Zhang,Qi[BioorganicandMedicinalChemistryLetters,2009,vol.19,#21,p.6032-6037]

[7]Locationinpatent:experimentalpartLv,Kai;Sun,Yexin;Sun,Lanyin;Wei,Zengquan;Guo,Huiyuan;Wu,Jinwei;Liu,Mingliang[ChemMedChem,2012,vol.7,#7,p.1230-1236]

541-41-3

145790-51-8

C27H37NO7Si

[1]Burtoloso,AntonioCarlosB.;Correia,CarlosRoqueD.[JournalofOrganometallicChemistry,2005,vol.690,#24-25,p.5636-5646]

145790-51-8 | (S)-2-(tert-Butoxycarbonylamino)-3-(tert-butyldiphenylsilyloxy)propanoic acid