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147403-03-0,MFCD20278186
Catalog No.:AA001ET2

147403-03-0 | Azilsartan

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
98%
in stock  
$6.00   $4.00
- +
50mg
98%
in stock  
$7.00   $5.00
- +
100mg
98%
in stock  
$9.00   $7.00
- +
250mg
98%
in stock  
$14.00   $10.00
- +
1g
98%
in stock  
$27.00   $19.00
- +
5g
98%
in stock  
$113.00   $79.00
- +
25g
98%
in stock  
$421.00   $295.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001ET2
Chemical Name:
Azilsartan
CAS Number:
147403-03-0
Molecular Formula:
C25H20N4O5
Molecular Weight:
456.4501
MDL Number:
MFCD20278186
SMILES:
CCOc1nc2c(n1Cc1ccc(cc1)c1ccccc1c1[nH]oc(=O)n1)c(ccc2)C(=O)O
Properties
Computed Properties
 
Complexity:
783  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
7  
XLogP3:
4.4  

Literature

Title: Azilsartan and its Zn(II) complex. Synthesis, anticancer mechanisms of action and binding to bovine serum albumin.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20180401

Title: Efficacy and safety of 10-mg azilsartan compared with 8-mg candesartan cilexetil in Japanese patients with hypertension: a randomized crossover non-inferiority trial.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20140901

Title: Evaluation of the efficacy and tolerability of fixed-dose combination therapy of azilsartan and amlodipine besylate in Japanese patients with grade I to II essential hypertension.

Journal: Clinical therapeutics 20140501

Title: Assessment of the environmental fate and effects of azilsartan, a selective antagonist of angiotensin II type 1.

Journal: Chemosphere 20120601

Title: Comparison of the efficacy and safety of azilsartan with that of candesartan cilexetil in Japanese patients with grade I-II essential hypertension: a randomized, double-blind clinical study.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20120501

Title: Differential pharmacology and benefit/risk of azilsartan compared to other sartans.

Journal: Vascular health and risk management 20120101

Title: Critical evaluation of the efficacy and tolerability of azilsartan.

Journal: Vascular health and risk management 20120101

Title: Clinical utility of azilsartan-chlorthalidone fixed combination in the management of hypertension.

Journal: Vascular health and risk management 20120101

Title: Azilsartan treatment improves insulin sensitivity in obese spontaneously hypertensive Koletsky rats.

Journal: Diabetes, obesity & metabolism 20111201

Title: Comparison of the novel angiotensin II receptor blocker azilsartan medoxomil vs valsartan by ambulatory blood pressure monitoring.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20110701

Title: In vitro antagonistic properties of a new angiotensin type 1 receptor blocker, azilsartan, in receptor binding and function studies.

Journal: The Journal of pharmacology and experimental therapeutics 20110301

Title: Azilsartan: a newly approved angiotensin II receptor blocker.

Journal: Cardiology in review 20110101

Title: TAK-536, a new AT1 receptor blocker, improves glucose intolerance and adipocyte differentiation.

Journal: American journal of hypertension 20070501

Title: Ojima M, Igata H, Tanaka M, In vitro antagonistic properties of a new angiotensin type 1 receptor blocker, azilsartan, in receptor binding and function studies. J Pharmacol Exp Ther. 2011 Mar;336(3):801-8.

Title: Weltman R, Brands CM, Corral E, Assessment of the environmental fate and effects of azilsartan, a selective antagonist of angiotensin II type 1. Chemosphere. 2012 Jun;87(11):1323-9.

Title: Pierini D, Anderson KV. Azilsartan medoxomil/chlorthalidone: a new fixed-dose combination antihypertensive. Ann Pharmacother. 2013 May;47(5):694-703.

Title: Iwai M, Chen R, Imura Y, Horiuchi M. TAK-536, a new AT1 receptor blocker, improves glucose intolerance and adipocyte differentiation. Am J Hypertens. 2007 May;20(5):579-86.

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