Home Other Building Blocks 149385-65-9
149385-65-9,MFCD06659094
Catalog No.:AA00AP5W

149385-65-9 | H-ILE-ILE-GLY-LEU-MET-OH

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1mg
≥95%
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$181.00   $127.00
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00AP5W
Chemical Name:
H-ILE-ILE-GLY-LEU-MET-OH
CAS Number:
149385-65-9
Molecular Formula:
C25H47N5O6S
Molecular Weight:
545.7356
MDL Number:
MFCD06659094
SMILES:
CSCC[C@@H](C(=O)O)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H]([C@H](CC)C)NC(=O)[C@H]([C@H](CC)C)N)CC(C)C
Properties
Computed Properties
 
Complexity:
766  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
6  
Rotatable Bond Count:
18  
XLogP3:
-1.1  

Literature

Title: Milton NG, et al. The amyloid-beta peptide binds to cyclin B1 and increases human cyclin-dependent kinase-1 activity. Neurosci Lett. 2002 Apr 5;322(2):131-3.

Title: Misiti F, et al. Fragment 31-35 of beta-amyloid peptide induces neurodegeneration in rat cerebellar granule cells via bax gene expression and caspase-3 activation. A crucial role for the redox state of methionine-35 residue. Neurochem Int. 2006 Oct;49(5):525-32.

Title: M Jesús Pérez de Vega, et al. Synthesis and biological properties of beta-turned Abeta(31-35) constrained analogues. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2078-82.

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