Home Other Building Blocks 1506-47-4
1506-47-4,MFCD00446913
Catalog No.:AA001MOE

1506-47-4 | 2,6-Piperazinedione, 4,4'-(1,2-ethanediyl)bis-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95%
2 weeks  
$257.00   $180.00
- +
250mg
95%
2 weeks  
$373.00   $261.00
- +
1g
95%
2 weeks  
$1,005.00   $704.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001MOE
Chemical Name:
2,6-Piperazinedione, 4,4'-(1,2-ethanediyl)bis-
CAS Number:
1506-47-4
Molecular Formula:
C10H14N4O4
Molecular Weight:
254.2426
MDL Number:
MFCD00446913
SMILES:
O=C1CN(CCN2CC(=O)NC(=O)C2)CC(=O)N1
NSC Number:
129942
Properties
Computed Properties
 
Complexity:
339  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
-1.8  

Literature

Title: Antimetastatic activities and mechanisms of bisdioxopiperazine compounds.

Journal: Anti-cancer agents in medicinal chemistry 20100901

Title: A mouse model for studying the interaction of bisdioxopiperazines with topoisomerase IIalpha in vivo.

Journal: Molecular pharmacology 20071001

Title: Separation of bisdioxopiperazine- and vanadate resistance in topoisomerase II.

Journal: Biochemical and biophysical research communications 20050902

Title: Probing the role of linker substituents in bisdioxopiperazine analogs for activity against wild-type and mutant human topoisomerase II alpha.

Journal: Molecular pharmacology 20030501

Title: Evidence from studies with intact mammalian cells that merbarone and bis(dioxopiperazine)s are topoisomerase II poisons.

Journal: Drug and chemical toxicology 20030201

Title: The catalytic DNA topoisomerase II inhibitor ICRF-193 and all-trans retinoic acid cooperatively induce granulocytic differentiation of acute promyelocytic leukemia cells: candidate drugs for chemo-differentiation therapy against acute promyelocytic leukemia.

Journal: Experimental hematology 20021101

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SDS
Tags:1506-47-4 Molecular Formula|1506-47-4 MDL|1506-47-4 SMILES|1506-47-4 2,6-Piperazinedione, 4,4'-(1,2-ethanediyl)bis-