Home Amines 154-69-8
154-69-8,MFCD00012815
Catalog No.:AA00AOG5

154-69-8 | Tripelennamine hydrochloride

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1g
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in stock  
$12.00   $8.00
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5g
98%
in stock  
$34.00   $24.00
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25g
98%
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$96.00   $68.00
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100g
98%
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$287.00   $201.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00AOG5
Chemical Name:
Tripelennamine hydrochloride
CAS Number:
154-69-8
Molecular Formula:
C16H22ClN3
Molecular Weight:
291.8190
MDL Number:
MFCD00012815
SMILES:
CN(CCN(c1ccccn1)Cc1ccccc1)C.Cl
NSC Number:
409943
Properties
Properties
 
BP:
387.8°C at 760 mmHg  
Form:
Solid  
MP:
192-193 °C  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
236  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  

Downstream Synthesis Route
7647-01-0   
cobalt(II)chloridehexahydrate 
  154-69-8    220156-62-7 

[1]ActaCrystallographica,SectionC:CrystalStructureCommunications,1998,vol.54,p.1748-1750

154-69-8   
cucurbit7uril 
 
tripelennaminemonohydrochloride-cucurbit7uril1:1complex 

[1]JournalofPhysicalOrganicChemistry,2016,vol.29,p.101-106

Literature

Title: pH-dependent complexation of histamine H1 receptor antagonists and human serum albumin studied by UV resonance Raman spectroscopy.

Journal: The journal of physical chemistry. B 20120329

Title: Cationic amphiphilic drugs are potent inhibitors of yeast sporulation.

Journal: PloS one 20120101

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: A predictive ligand-based Bayesian model for human drug-induced liver injury.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201

Title: Medullary pain facilitating neurons mediate allodynia in headache-related pain.

Journal: Annals of neurology 20090201

Title: Myasthenia gravis-like syndrome in a Hereford heifer.

Journal: Journal of veterinary internal medicine 20080101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Involvement of histamine H1 and H2 receptors in the regulation of STAT-1 phosphorylation: inverse agonism exhibited by the receptor antagonists.

Journal: International immunopharmacology 20050701

Title: Mast cell--pituitary interaction: modulation by serine phospholipids.

Journal: Die Pharmazie 20041201

Title: Role of N-methyl-D-aspartate receptors in gastric mucosal blood flow induced by histamine.

Journal: Journal of neuroscience research 20040901

Title: H1-receptor antagonist, tripelennamine, does not affect arterial hypoxemia in exercising Thoroughbreds.

Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20020401

Title: Managing patients with local anesthetic complications using alternative methods.

Journal: Pennsylvania dental journal 20020101

Title: Does the neurotransmitter transporter underlie adaptation at a histaminergic photoreceptor synapse?

Journal: Visual neuroscience 20020101

Title: Antihistaminic-opioid combination: effect on locomotor activity in mice.

Journal: Polish journal of pharmacology and pharmacy 19880101

Title: Antihistaminics enhance morphine-, but not amphetamine- and scopolamine-induced hyperactivity in mice.

Journal: Psychopharmacology 19870101

Title: Enhancement of morphine-induced hyperactivity by antihistaminic drugs in mice.

Journal: Archives internationales de pharmacodynamie et de therapie 19861201

Title: Behavioral and developmental effects of prenatal exposure to pentazocine and tripelennamine combinations.

Journal: Neurobehavioral toxicology and teratology 19860101

Title: Fatal intracranial hemorrhage associated with phenylpropanolamine, pentazocine, and tripelennamine overdose.

Journal: The Journal of emergency medicine 19850101

Title: Central nervous system complications of addiction to 'T's and Blues'.

Journal: Neurology 19820601

Title: Pentazocine/tripelennamine (T's and blues) abuse: a five year survey of St. Louis, Missouri.

Journal: Drug and alcohol dependence 19820101

Title: Pulmonary angiothrombosis caused by 'blue velvet' addiction.

Journal: Annals of internal medicine 19701101

Title: An unusual case of antihistamine intoxication.

Journal: The Journal of pediatrics 19671001

Title: Manohar M, et al. H1-receptor antagonist, tripelennamine, does not affect arterial hypoxemia in exercising Thoroughbreds. J Appl Physiol. 2002 Apr;92(4):1515-23.

Title: Wasfi IA, et al. Comparative disposition of tripelennamine in horses and camels after intravenous administration. J Vet Pharmacol Ther. 2000 Jun;23(3):145-52.

Title: Yeh SY, et al. The pharmacokinetics of pentazocine and tripelennamine. Clin Pharmacol Ther. 1986 Jun;39(6):669-76.

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