Catalog No.:AA00APSV

154303-05-6 | Echistatin H-Glu-Cys-Glu-Ser-Gly-Pro-Cys-Cys-Arg-Asn-Cys-Lys-Phe-Leu-Lys-Glu-Gly-Thr-Ile-Cys-Lys-Arg-Ala-Arg-Gly-Asp-Asp-Met-Asp-Asp-Tyr-Cys-Asn-Gly-Lys-Thr-Cys-Asp-Cys-Pro-Arg-Asn-Pro-His-Lys-Gly-Pro-Ala-Thr-OH (Disulfide bonds between Cys2 and Cys11/Cys7 and Cys32/Cys8 and Cys37/Cys20 and Cys39)

Name: Name:Echistatin H-Glu-Cys-Glu-Ser-Gly-Pro-Cys-Cys-Arg-Asn-Cys-Lys-Phe-Leu-Lys-Glu-Gly-Thr-Ile-Cys-Lys-Arg-Ala-Arg-Gly-Asp-Asp-Met-Asp-Asp-Tyr-Cys-Asn-Gly-Lys-Thr-Cys-Asp-Cys-Pro-Arg-Asn-Pro-His-Lys-Gly-Pro-Ala-Thr-OH (Disulfide bonds between Cys2 and Cys11/Cys7 and Cys32/Cys8 and Cys37/Cys20 and Cys39)
Brand: AABLOCKS
SKU: AA00APSV
Rating: 90 (10 reviews)

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Technical Information
Properties
Literature
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Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA00APSV

Chemical Name:

Echistatin H-Glu-Cys-Glu-Ser-Gly-Pro-Cys-Cys-Arg-Asn-Cys-Lys-Phe-Leu-Lys-Glu-Gly-Thr-Ile-Cys-Lys-Arg-Ala-Arg-Gly-Asp-Asp-Met-Asp-Asp-Tyr-Cys-Asn-Gly-Lys-Thr-Cys-Asp-Cys-Pro-Arg-Asn-Pro-His-Lys-Gly-Pro-Ala-Thr-OH (Disulfide bonds between Cys2 and Cys11/Cys7 and Cys32/Cys8 and Cys37/Cys20 and Cys39)

CAS Number:

154303-05-6

Molecular Formula:

C217H341N71O74S9

Molecular Weight:

5417.0457

SMILES:

NCCCCC1NC(=O)C2CSSCC(NC(=O)C(CC(=O)O)NC(=O)C3CSSCC4NC(=O)C(CSSCC(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CCCNC(=N)N)C)CCCNC(=N)N)CC(=O)O)CC(=O)O)CCSC)CC(=O)O)CC(=O)O)Cc1ccc(cc1)O)C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N3)C(O)C)CCCCN)CC(=O)N)NC(=O)C1CCCN1C(=O)CNC(=O)C(CO)NC(=O)C(CCC(=O)O)NC(=O)C(CSSCC(NC(=O)C(NC(=O)C(NC4=O)CCCNC(=N)N)CC(=O)N)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N2)C(CC)C)C(O)C)CCC(=O)O)CCCCN)CC(C)C)Cc1ccccc1)CCCCN)NC(=O)C(CCC(=O)O)N)C(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)NCC(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)O)C(O)C)C)CCCCN)Cc1nc[nH]c1)CC(=O)N)CCCNC(=N)N

Properties

Literature

Title: J Musial, et al. Inhibition of platelet adhesion to surfaces of extracorporeal circuits by disintegrins. RGD-containing peptides from viper venoms. Circulation. 1990 Jul;82(1):261-73.

Title: M Sato, et al. Echistatin is a potent inhibitor of bone resorption in culture. J Cell Biol. 1990 Oct;111(4):1713-23.

Title: C C Kumar, et al. Biochemical characterization of the binding of echistatin to integrin alphavbeta3 receptor. J Pharmacol Exp Ther. 1997 Nov;283(2):843-53.

Title: I Wierzbicka-Patynowski, et al. Structural requirements of echistatin for the recognition of alpha(v)beta(3) and alpha(5)beta(1) integrins. J Biol Chem. 1999 Dec 31;274(53):37809-14.

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SDS