Title: The role of copper(II) and zinc(II) in the degradation of human and murine IAPP by insulin-degrading enzyme.
Journal: Journal of mass spectrometry : JMS 20140401
Title: Copper(II)-human amylin complex protects pancreatic cells from amylin toxicity.
Journal: Physical chemistry chemical physics : PCCP 20130814
Title: Inhibition of human islet amyloid polypeptide or amylin aggregation by two manganese-salen derivatives.
Journal: European journal of pharmacology 20130505
Title: Probing ion channel activity of human islet amyloid polypeptide (amylin).
Journal: Biochimica et biophysica acta 20121201
Title: [D-Leu-4]-OB3, a synthetic peptide amide with leptin-like activity, augments the effects of orally delivered exenatide and pramlintide acetate on energy balance and glycemic control in insulin-resistant male C57BLK/6-m db/db mice.
Journal: Regulatory peptides 20121110
Title: How to blast osteoblasts? Novel dicarba analogues of amylin-(1-8) to treat osteoporosis.
Journal: Bioorganic & medicinal chemistry 20121015
Title: Immune regulatory properties of allogeneic adipose-derived mesenchymal stem cells in the treatment of experimental autoimmune diabetes.
Journal: Diabetes 20121001
Title: Effect of pramlintide on prandial glycemic excursions during closed-loop control in adolescents and young adults with type 1 diabetes.
Journal: Diabetes care 20121001
Title: Amylin blunts hyperphagia and reduces weight and fat gain during recovery in socially stressed rats.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20120915
Title: Sensitivity of amyloid formation by human islet amyloid polypeptide to mutations at residue 20.
Journal: Journal of molecular biology 20120810
Title: Generic inhibition of amyloidogenic proteins by two naphthoquinone-tryptophan hybrid molecules.
Journal: Proteins 20120801
Title: Deamidation accelerates amyloid formation and alters amylin fiber structure.
Journal: Journal of the American Chemical Society 20120801
Title: Interactions of amylinergic and melanocortinergic systems in the control of food intake and body weight in rodents.
Journal: Diabetes, obesity & metabolism 20120701
Title: Changes in gastrointestinal hormone responses, insulin sensitivity, and beta-cell function within 2 weeks after gastric bypass in non-diabetic subjects.
Journal: Obesity surgery 20120701
Title: A mechanistic insight into the amyloidogenic structure of hIAPP peptide revealed from sequence analysis and molecular dynamics simulation.
Journal: Biophysical chemistry 20120701
Title: Curcumin modulates the self-assembly of the islet amyloid polypeptide by disassembling α-helix.
Journal: Biochemical and biophysical research communications 20120615
Title: Control of energy homeostasis by amylin.
Journal: Cellular and molecular life sciences : CMLS 20120601
Title: Polymeric particles for the controlled release of human amylin.
Journal: Colloids and surfaces. B, Biointerfaces 20120601
Title: Extensive amyloid formation in transplanted microencapsulated mouse and human islets.
Journal: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20120601
Title: Conformational dynamics of human IAPP monomers.
Journal: Biophysical chemistry 20120601
Title: [Construction of human phage antibody library and screening for human monoclonal antibodies of amylin].
Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20120601
Title: GLP-1R and amylin agonism in metabolic disease: complementary mechanisms and future opportunities.
Journal: British journal of pharmacology 20120501
Title: Pharmacological characterization of rat amylin receptors: implications for the identification of amylin receptor subtypes.
Journal: British journal of pharmacology 20120501
Title: Translational control of glucose-induced islet amyloid polypeptide production in pancreatic islets.
Journal: Endocrinology 20120501
Title: Two-dimensional infrared spectroscopy reveals the complex behaviour of an amyloid fibril inhibitor.
Journal: Nature chemistry 20120501
Title: [Combination therapy of amylin and leptin].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20120501
Title: Amylin improves the effect of leptin on insulin sensitivity in leptin-resistant diet-induced obese mice.
Journal: American journal of physiology. Endocrinology and metabolism 20120415
Title: Analysis of the inhibition and remodeling of islet amyloid polypeptide amyloid fibers by flavanols.
Journal: Biochemistry 20120403
Title: Role of amino acid hydrophobicity, aromaticity, and molecular volume on IAPP(20-29) amyloid self-assembly.
Journal: Proteins 20120401
Title: Accumulation of intrahepatic islet amyloid in a nonhuman primate transplant model.
Journal: Endocrinology 20120401
Title: Membrane disruption and early events in the aggregation of the diabetes related peptide IAPP from a molecular perspective.
Journal: Accounts of chemical research 20120320
Title: Silibinin inhibits the toxic aggregation of human islet amyloid polypeptide.
Journal: Biochemical and biophysical research communications 20120316
Title: Amylin-leptin coadministration stimulates central histaminergic signaling in rats.
Journal: Brain research 20120309
Title: Unique example of amyloid aggregates stabilized by main chain H-bond instead of the steric zipper: molecular dynamics study of the amyloidogenic segment of amylin wild-type and mutants.
Journal: Journal of molecular modeling 20120301
Title: Morin hydrate inhibits amyloid formation by islet amyloid polypeptide and disaggregates amyloid fibers.
Journal: Protein science : a publication of the Protein Society 20120301
Title: Functional coupling reactions of human amylin receptor and nicotinic acetylcholine receptors in rat brain neurons.
Journal: Sheng li xue bao : [Acta physiologica Sinica] 20120225
Title: Hyperamylinemia contributes to cardiac dysfunction in obesity and diabetes: a study in humans and rats.
Journal: Circulation research 20120217
Title: Peptide-cleaving agents for human islet amyloid polypeptide containing substrate recognition site based on quinoxaline: cleavage efficiency enhanced by lowering substrate concentration.
Journal: Bioorganic & medicinal chemistry letters 20120215
Title: Effect of sequence variation on the mechanical response of amyloid fibrils probed by steered molecular dynamics simulation.
Journal: Biophysical journal 20120208
Title: The acute effects of olanzapine on ghrelin secretion, CCK sensitivity, meal size, locomotor activity and body temperature.
Journal: International journal of obesity (2005) 20120201
Title: Involvement of the extracellular signal-regulated kinase 1/2 signaling pathway in amylin's eating inhibitory effect.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20120201
Title: Gastrointestinal regulatory peptides and central nervous system mechanisms of weight control.
Journal: Current opinion in endocrinology, diabetes, and obesity 20120201
Title: Protective effects of cleavage agents on INS-1 cells against h-IAPP-induced apoptosis.
Journal: Chemical communications (Cambridge, England) 20120114
Title: β-Amyloid protein (Aβ) and human amylin regulation of apoptotic genes occurs through the amylin receptor.
Journal: Apoptosis : an international journal on programmed cell death 20120101
Title: Amylin is a novel neuropeptide with potential maternal functions in the rat.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120101
Title: Amylin and leptin activate overlapping signalling pathways in an additive manner in mouse GT1-7 hypothalamic, C₂C₁₂ muscle and AML12 liver cell lines.
Journal: Diabetologia 20120101
Title: cJUN N-terminal kinase (JNK) activation mediates islet amyloid-induced beta cell apoptosis in cultured human islet amyloid polypeptide transgenic mouse islets.
Journal: Diabetologia 20120101
Title: Characterization of insulin degrading enzyme and other amyloid-β degrading proteases in human serum: a role in Alzheimer's disease?
Journal: Journal of Alzheimer's disease : JAD 20120101
Title: Effects of amylin on eating and adiposity.
Journal: Handbook of experimental pharmacology 20120101
Title: Application of photochemical cross-linking to the study of oligomerization of amyloidogenic proteins.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Histological staining of amyloid and pre-amyloid peptides and proteins in mouse tissue.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Lipid interaction and membrane perturbation of human islet amyloid polypeptide monomer and dimer by molecular dynamics simulations.
Journal: PloS one 20120101
Title: Coffee components inhibit amyloid formation of human islet amyloid polypeptide in vitro: possible link between coffee consumption and diabetes mellitus.
Journal: Journal of agricultural and food chemistry 20111228
Title: [Investigation of amylin level changes among obese patients at different glucose metabolic states and effects of rosiglitazone intervention].
Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20111218
Title: Glucoregulatory effects and prolonged duration of action of davalintide: a novel amylinomimetic peptide.
Journal: Diabetes, obesity & metabolism 20111201
Title: Novel strategy for the use of leptin for obesity therapy.
Journal: Expert opinion on biological therapy 20111201
Title: Evidence for the role of hindbrain orexin-1 receptors in the control of meal size.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20111201
Title: Sugar-based peptidomimetics inhibit amyloid β-peptide aggregation.
Journal: European journal of medicinal chemistry 20111201
Title: Drug treatment of obesity.
Journal: The Psychiatric clinics of North America 20111201
Title: The gut: key to treating obesity in adolescents?
Journal: Journal of pediatric gastroenterology and nutrition 20111201
Title: Amylinergic control of food intake in lean and obese rodents.
Journal: Physiology & behavior 20111130
Title: A simple and rapid method for identifying and semi-quantifying peptide hormones in isolated pancreatic islets by direct-tissue matrix-assisted laser desorption ionization time-of-flight mass spectrometry.
Journal: Rapid communications in mass spectrometry : RCM 20111130
Title: Involvement of ATP-sensitive potassium (K(ATP)) channels in the loss of beta-cell function induced by human islet amyloid polypeptide.
Journal: The Journal of biological chemistry 20111125
Title: Aβ inhibition of ionic conductance in mouse basal forebrain neurons is dependent upon the cellular prion protein PrPC.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20111109
Title: Novel potential regulators of maternal adaptations during lactation: tuberoinfundibular peptide 39 and amylin.
Journal: Journal of neuroendocrinology 20111101
Title: Changes in differential functional magnetic resonance signals in the rodent brain elicited by mixed-nutrient or protein-enriched meals.
Journal: Gastroenterology 20111101
Title: Pharmacological management of type 2 diabetes mellitus: an update.
Journal: Current diabetes reviews 20111101
Title: Effects of cholesterol on pore formation in lipid bilayers induced by human islet amyloid polypeptide fragments: a coarse-grained molecular dynamics study.
Journal: Physical review. E, Statistical, nonlinear, and soft matter physics 20111101
Title: Copper(II) complexes of rat amylin fragments.
Journal: Dalton transactions (Cambridge, England : 2003) 20111014
Title: Clustering and internalization of toxic amylin oligomers in pancreatic cells require plasma membrane cholesterol.
Journal: The Journal of biological chemistry 20111014
Title: 2DIR spectroscopy of human amylin fibrils reflects stable β-sheet structure.
Journal: Journal of the American Chemical Society 20111012
Title: Disruption of circadian rhythms accelerates development of diabetes through pancreatic beta-cell loss and dysfunction.
Journal: Journal of biological rhythms 20111001
Title: Amylin effect in extrapancreatic tissues participating in glucose homeostasis, in normal, insulin-resistant and type 2 diabetic state.
Journal: Peptides 20111001
Title: Designed hairpin peptides interfere with amyloidogenesis pathways: fibril formation and cytotoxicity inhibition, interception of the preamyloid state.
Journal: Biochemistry 20110927
Title: Combined amylin-leptin treatment lowers blood pressure and adiposity in lean and obese rats.
Journal: International journal of obesity (2005) 20110901
Title: IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20110901
Title: The amylin peptide implicated in type 2 diabetes stimulates copper-mediated carbonyl group and ascorbate radical formation.
Journal: Free radical biology & medicine 20110815
Title: Butyrylcholinesterase interactions with amylin may protect pancreatic cells in metabolic syndrome.
Journal: Journal of cellular and molecular medicine 20110801
Title: Amylin and selective glucoregulatory peptide alterations during prolonged exercise.
Journal: Medicine and science in sports and exercise 20110801
Title: Differential roles of calcitonin family peptides in the dendrite formation and spinogenesis of the cerebral cortex in vitro.
Journal: Neuropeptides 20110801
Title: Evaluation of plasma islet amyloid polypeptide and serum glucose and insulin concentrations in nondiabetic cats classified by body condition score and in cats with naturally occurring diabetes mellitus.
Journal: American journal of veterinary research 20110801
Title: Influence of high-fat feeding, diet-induced obesity, and hyperamylinemia on the sensitivity to acute amylin.
Journal: Physiology & behavior 20110725
Title: Hexafluoroisopropanol induces amyloid fibrils of islet amyloid polypeptide by enhancing both hydrophobic and electrostatic interactions.
Journal: The Journal of biological chemistry 20110708
Title: A two-site mechanism for the inhibition of IAPP amyloidogenesis by zinc.
Journal: Journal of molecular biology 20110708
Title: Evaluation of metabolic risk marker in obesity-related glomerulopathy.
Journal: Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20110701
Title: Exendin-4 increases islet amyloid deposition but offsets the resultant beta cell toxicity in human islet amyloid polypeptide transgenic mouse islets.
Journal: Diabetologia 20110701
Title: Mechanism of amylin fibrillization enhancement by heparin.
Journal: The Journal of biological chemistry 20110701
Title: Simultaneous capillary electrophoresis competitive immunoassay for insulin, glucagon, and islet amyloid polypeptide secretion from mouse islets of Langerhans.
Journal: Journal of chromatography. A 20110701
Title: Islet amyloid polypeptide, islet amyloid, and diabetes mellitus.
Journal: Physiological reviews 20110701
Title: Comparing the structural properties of human and rat islet amyloid polypeptide by MD computer simulations.
Journal: Biophysical chemistry 20110601
Title: Pramlintide and the treatment of diabetes: a review of the data since its introduction.
Journal: Expert opinion on pharmacotherapy 20110601
Title: To study various concentrations of magnesium and aluminium on amylin hormone conformation.
Journal: Pakistan journal of biological sciences : PJBS 20110601
Title: Heterogeneous triangular structures of human islet amyloid polypeptide (amylin) with internal hydrophobic cavity and external wrapping morphology reveal the polymorphic nature of amyloid fibrils.
Journal: Biomacromolecules 20110509
Title: Amyloid in the islets of Langerhans: thoughts and some historical aspects.
Journal: Upsala journal of medical sciences 20110501
Title: Steve Woods's contribution to research on amylin's eating inhibitory effect.
Journal: Physiology & behavior 20110418
Title: Heterogeneous amylin fibril growth mechanisms imaged by total internal reflection fluorescence microscopy.
Journal: Biochemistry 20110412
Title: Cyclin-dependent kinase 5 promotes pancreatic β-cell survival via Fak-Akt signaling pathways.
Journal: Diabetes 20110401
Title: Diabetes and pancreatic cancer: chicken or egg?
Journal: Pancreas 20110401
Title: [Analogues of amylin, alpha-glucosidase inhibitors and the digestive system in homeostasis regulation].
Journal: Vnitrni lekarstvi 20110401
Title: Structure and thermodynamics of amylin dimer studied by Hamiltonian-temperature replica exchange molecular dynamics simulations.
Journal: The journal of physical chemistry. B 20110331
Title: Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic β-cells: protective role of p62-positive cytoplasmic inclusions.
Journal: Cell death and differentiation 20110301
Title: TNF-α acutely upregulates amylin expression in murine pancreatic beta cells.
Journal: Diabetologia 20110301
Title: Delayed response of amylin levels after an oral glucose challenge in children with Prader-Willi syndrome.
Journal: Yonsei medical journal 20110301
Title: The molecular basis of distinct aggregation pathways of islet amyloid polypeptide.
Journal: The Journal of biological chemistry 20110225
Title: Inhibition of glycosaminoglycan-mediated amyloid formation by islet amyloid polypeptide and proIAPP processing intermediates.
Journal: Journal of molecular biology 20110225
Title: Evaluation of aluminium, manganese, copper and selenium effects on human islets amyloid polypeptide hormone aggregation.
Journal: Pakistan journal of biological sciences : PJBS 20110215
Title: Biphasic effects of insulin on islet amyloid polypeptide membrane disruption.
Journal: Biophysical journal 20110202
Title: New physiological effects of the incretin hormones GLP-1 and GIP.
Journal: Danish medical bulletin 20110201
Title: Structural polymorphism of human islet amyloid polypeptide (hIAPP) oligomers highlights the importance of interfacial residue interactions.
Journal: Biomacromolecules 20110110
Title: The role of aromatic side-chains in amyloid growth and membrane interaction of the islet amyloid polypeptide fragment LANFLVH.
Journal: European biophysics journal : EBJ 20110101
Title: Leptin and amylin act in an additive manner to activate overlapping signaling pathways in peripheral tissues: in vitro and ex vivo studies in humans.
Journal: Diabetes care 20110101
Title: β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency.
Journal: Diabetes 20110101
Title: Amylin may offer (more) help to treat postmenopausal obesity.
Journal: Endocrinology 20110101
Title: Islet amyloid polypeptide acts on glucose- stimulated beta cells to reduce voltage-gated calcium channel activation, intracellular Ca(2+) concentration, and insulin secretion.
Journal: Diabetes/metabolism research and reviews 20110101
Title: Primer on pramlintide, an amylin analog.
Journal: The Diabetes educator 20110101
Title: MCP-1 upregulates amylin expression in murine pancreatic β cells through ERK/JNK-AP1 and NF-κB related signaling pathways independent of CCR2.
Journal: PloS one 20110101
Title: Drosophila melanogaster as a model system for studies of islet amyloid polypeptide aggregation.
Journal: PloS one 20110101
Title: [Combination therapy of leptin and amylin for metabolic syndrome].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20110101
Title: Arx and Nkx2.2 compound deficiency redirects pancreatic alpha- and beta-cell differentiation to a somatostatin/ghrelin co-expressing cell lineage.
Journal: BMC developmental biology 20110101
Title: Associations of amylin with inflammatory markers and metabolic syndrome in apparently healthy Chinese.
Journal: PloS one 20110101
Title: Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiol.
Journal: PloS one 20110101
Title: Mechanistic studies of peptide self-assembly: transient α-helices to stable β-sheets.
Journal: Journal of the American Chemical Society 20101229
Title: Enhanced amylin-mediated body weight loss in estradiol-deficient diet-induced obese rats.
Journal: Endocrinology 20101201
Title: Positive inotropic, positive chronotropic and coronary vasodilatory effects of rat amylin: mechanisms of amylin-induced positive inotropy.
Journal: Acta physiologica Hungarica 20101201
Title: Changes in dynamic insulin and gastrointestinal hormone secretion in obese children.
Journal: Journal of pediatric endocrinology & metabolism : JPEM 20101201
Title: The chaperone proteins HSP70, HSP40/DnaJ and GRP78/BiP suppress misfolding and formation of β-sheet-containing aggregates by human amylin: a potential role for defective chaperone biology in Type 2 diabetes.
Journal: The Biochemical journal 20101115
Title: Cyclen-hybrid compound captures copper to protect INS-1 cells from islet amyloid polypeptide cytotoxicity by inhibiting and lysing effects.
Journal: Chemical communications (Cambridge, England) 20101114
Title: Efficacy and harms of the hypoglycemic agent pramlintide in diabetes mellitus.
Journal: Annals of family medicine 20101101
Title: Dose accuracy and injection force of disposable pens delivering pramlintide for the treatment of diabetes.
Journal: Journal of diabetes science and technology 20101101
Title: Stable and metastable states of human amylin in solution.
Journal: Biophysical journal 20101006
Title: Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.
Journal: Nature immunology 20101001
Title: [Visualization of amyloid formation processes on cell membranes: gangliosides as key molecules for the onset of amyloidosis].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20101001
Title: The flavanol (-)-epigallocatechin 3-gallate inhibits amyloid formation by islet amyloid polypeptide, disaggregates amyloid fibrils, and protects cultured cells against IAPP-induced toxicity.
Journal: Biochemistry 20100921
Title: Self-assembling pathway of HiApp fibrils within lipid bilayers.
Journal: Chembiochem : a European journal of chemical biology 20100903
Title: 'Weighing in' on synergy: preclinical research on neurohormonal anti-obesity combinations.
Journal: Brain research 20100902
Title: Enhanced weight loss following coadministration of pramlintide with sibutramine or phentermine in a multicenter trial.
Journal: Obesity (Silver Spring, Md.) 20100901
Title: Serum levels of proamylin and amylin in normal subjects and patients with impaired glucose regulation and type 2 diabetes mellitus.
Journal: Acta diabetologica 20100901
Title: The N-terminal fragment of human islet amyloid polypeptide is non-fibrillogenic in the presence of membranes and does not cause leakage of bilayers of physiologically relevant lipid composition.
Journal: Biochimica et biophysica acta 20100901
Title: Exendin-4 protects pancreatic beta cells from human islet amyloid polypeptide-induced cell damage: potential involvement of AKT and mitochondria biogenesis.
Journal: Diabetes, obesity & metabolism 20100901
Title: Basal plasma levels of insulin, leptin, ghrelin, and amylin do not signal adiposity in rats recovering from forced overweight.
Journal: Endocrinology 20100901
Title: The effect of curcumin on human islet amyloid polypeptide misfolding and toxicity.
Journal: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20100901
Title: Central amylin acts as an adiposity signal to control body weight and energy expenditure.
Journal: Physiology & behavior 20100804
Title: Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin.
Journal: The Journal of nutritional biochemistry 20100801
Title: Insights into amylin-leptin synergy.
Journal: Trends in endocrinology and metabolism: TEM 20100801
Title: Pathologic changes and glucose homeostasis according to expression of human islet amyloid polypeptide in type 2 diabetic patients.
Journal: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20100801
Title: Up-regulated pancreatic tissue microRNA-375 associates with human type 2 diabetes through beta-cell deficit and islet amyloid deposition.
Journal: Pancreas 20100801
Title: Noradrenergic neurons of the area postrema mediate amylin's hypophagic action.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100801
Title: Residue-specific, real-time characterization of lag-phase species and fibril growth during amyloid formation: a combined fluorescence and IR study of p-cyanophenylalanine analogs of islet amyloid polypeptide.
Journal: Journal of molecular biology 20100723
Title: The sulfated triphenyl methane derivative acid fuchsin is a potent inhibitor of amyloid formation by human islet amyloid polypeptide and protects against the toxic effects of amyloid formation.
Journal: Journal of molecular biology 20100716
Title: Brainstem mechanisms of amylin-induced anorexia.
Journal: Physiology & behavior 20100714
Title: Role of zinc in human islet amyloid polypeptide aggregation.
Journal: Journal of the American Chemical Society 20100707
Title: Differences between amyloid toxicity in alpha and beta cells in human and mouse islets and the role of caspase-3.
Journal: Diabetologia 20100701
Title: Identification of central projections from amylin-activated neurons to the lateral hypothalamus.
Journal: Brain research 20100602
Title: Increased secretion of amylin in women with polycystic ovary syndrome.
Journal: Fertility and sterility 20100601
Title: Oligomers of beta-amyloid are sequestered into and seed new plaques in the brains of an AD mouse model.
Journal: Experimental neurology 20100601
Title: Superior appetite hormone profile after equivalent weight loss by gastric bypass compared to gastric banding.
Journal: Obesity (Silver Spring, Md.) 20100601
Title: Postprandial response of plasma insulin, amylin and acylated ghrelin to various test meals in lean and obese cats.
Journal: The British journal of nutrition 20100601
Title: The role of amylin in the control of energy homeostasis.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100601
Title: Adjunct therapy for type 1 diabetes mellitus.
Journal: Nature reviews. Endocrinology 20100601
Title: Effect of the disulfide bond on the monomeric structure of human amylin studied by combined Hamiltonian and temperature replica exchange molecular dynamics simulations.
Journal: The journal of physical chemistry. B 20100527
Title: Multi-hormonal weight loss combinations in diet-induced obese rats: therapeutic potential of cholecystokinin?
Journal: Physiology & behavior 20100511
Title: Amylin reduces plasma glucagon concentration in cats.
Journal: Veterinary journal (London, England : 1997) 20100501
Title: Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?
Journal: The Journal of clinical endocrinology and metabolism 20100501
Title: In situ misfolding of human islet amyloid polypeptide at interfaces probed by vibrational sum frequency generation.
Journal: Journal of the American Chemical Society 20100421
Title: The threshold of amylin-induced anorexia is lower in chicks selected for low compared to high juvenile body weight.
Journal: Behavioural brain research 20100402
Title: Meal-induced hormone responses in a rat model of Roux-en-Y gastric bypass surgery.
Journal: Endocrinology 20100401
Title: Abeta and human amylin share a common toxicity pathway via mitochondrial dysfunction.
Journal: Proteomics 20100401
Title: Ester to amide switch peptides provide a simple method for preparing monomeric islet amyloid polypeptide under physiologically relevant conditions and facilitate investigations of amyloid formation.
Journal: Journal of the American Chemical Society 20100331
Title: The role of gut hormones in the regulation of body weight and energy homeostasis.
Journal: Molecular and cellular endocrinology 20100325
Title: Reduced amylin levels are associated with low bone mineral density in women with anorexia nervosa.
Journal: Bone 20100301
Title: Amylin(1-8) is devoid of anabolic activity in bone.
Journal: Calcified tissue international 20100301
Title: The role of pramlintide for weight loss.
Journal: The Annals of pharmacotherapy 20100301
Title: Sphingomyelinase dependent apoptosis of dendritic cells following treatment with amyloid peptides.
Journal: Journal of neuroimmunology 20100226
Title: Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes.
Journal: Regulatory peptides 20100225
Title: Amylin suppresses acetic acid-induced visceral pain and spinal c-fos expression in the mouse.
Journal: Neuroscience 20100217
Title: Design and study of peptide-based inhibitors of amylin cytotoxicity.
Journal: Bioorganic & medicinal chemistry letters 20100215
Title: The ability of rodent islet amyloid polypeptide to inhibit amyloid formation by human islet amyloid polypeptide has important implications for the mechanism of amyloid formation and the design of inhibitors.
Journal: Biochemistry 20100209
Title: Solution structures of rat amylin peptide: simulation, theory, and experiment.
Journal: Biophysical journal 20100203
Title: Gastrointestinal peptides and bone health.
Journal: Current opinion in endocrinology, diabetes, and obesity 20100201
Title: Davalintide (AC2307), a novel amylin-mimetic peptide: enhanced pharmacological properties over native amylin to reduce food intake and body weight.
Journal: International journal of obesity (2005) 20100201
Title: Comparison of the post-meal glucose response to different insulin bolus waveforms in insulin pump- and pre-meal pramlintide-treated type 1 diabetes patients.
Journal: Diabetes technology & therapeutics 20100201
Title: Aggregation properties of the peptide fragments derived from the 17-29 region of the human and rat IAPP: a comparative study with two PEG-conjugated variants of the human sequence.
Journal: The journal of physical chemistry. B 20100121
Title: Molecular basis for the recognition and cleavages of IGF-II, TGF-alpha, and amylin by human insulin-degrading enzyme.
Journal: Journal of molecular biology 20100115
Title: Interaction of leptin and amylin in the long-term maintenance of weight loss in diet-induced obese rats.
Journal: Obesity (Silver Spring, Md.) 20100101
Title: Tetracycline treatment retards the onset and slows the progression of diabetes in human amylin/islet amyloid polypeptide transgenic mice.
Journal: Diabetes 20100101
Title: Fatty acids induce amylin expression and secretion by pancreatic beta-cells.
Journal: American journal of physiology. Endocrinology and metabolism 20100101
Title: Mechanisms of amylin/leptin synergy in rodent models.
Journal: Endocrinology 20100101
Title: Roles of amylin in satiation, adiposity and brain development.
Journal: Forum of nutrition 20100101
Title: Synthetic alpha-helix mimetics as agonists and antagonists of islet amyloid polypeptide aggregation.
Journal: Angewandte Chemie (International ed. in English) 20100101
Title: Microwave assisted SPPS of amylin and its toxicity of the pure product to RIN-5F cells.
Journal: Biopolymers 20100101
Title: Managing highly insulin-resistant diabetes mellitus: weight loss approaches and medical management.
Journal: Postgraduate medicine 20100101
Title: Amylin. Insulin's super sidekick.
Journal: Diabetes self-management 20100101
Title: Evidence for a partially structured state of the amylin monomer.
Journal: Biophysical journal 20091202
Title: Central amylin expression and its induction in rat dams.
Journal: Journal of neurochemistry 20091201
Title: Obesity treatment: novel peripheral targets.
Journal: British journal of clinical pharmacology 20091201
Title: Pharmacologic management of the older patient with type 2 diabetes mellitus.
Journal: The American journal of geriatric pharmacotherapy 20091201
Title: Impaired processing of human pro-islet amyloid polypeptide is not a causative factor for fibril formation or membrane damage in vitro.
Journal: Biochemistry 20091124
Title: Annexin A5 directly interacts with amyloidogenic proteins and reduces their toxicity.
Journal: Biochemistry 20091110
Title: Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models--association with liver and adipose tissue effects.
Journal: American journal of physiology. Endocrinology and metabolism 20091101
Title: Age dependence of glucose tolerance in adult KK-Ay mice, a model of non-insulin dependent diabetes mellitus.
Journal: Lab animal 20091101
Title: A pilot trial of pramlintide home usage in adolescents with type 1 diabetes.
Journal: Pediatrics 20091101
Title: Cholesterol regulates assembly of human islet amyloid polypeptide on model membranes.
Journal: Journal of molecular biology 20091030
Title: Gut hormones: implications for the treatment of obesity.
Journal: Pharmacology & therapeutics 20091001
Title: It takes two to tango: combined amylin/leptin agonism as a potential approach to obesity drug development.
Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20091001
Title: Ganglioside-induced amyloid formation by human islet amyloid polypeptide in lipid rafts.
Journal: FEBS letters 20090903
Title: Pramlintide lowered glucose excursions and was well-tolerated in adolescents with type 1 diabetes: results from a randomized, single-blind, placebo-controlled, crossover study.
Journal: The Journal of pediatrics 20090901
Title: Randomized comparison of pramlintide or mealtime insulin added to basal insulin treatment for patients with type 2 diabetes.
Journal: Diabetes care 20090901
Title: Enhanced weight loss with pramlintide/metreleptin: an integrated neurohormonal approach to obesity pharmacotherapy.
Journal: Obesity (Silver Spring, Md.) 20090901
Title: Pramlintide in pediatric type 1 diabetes.
Journal: The Journal of pediatrics 20090901
Title: Amylin prevents TRAIL-mediated apoptotic effects of reserpine in the rat gastric mucosa.
Journal: Peptides 20090801
Title: Dynamics of beta-cell turnover: evidence for beta-cell turnover and regeneration from sources of beta-cells other than beta-cell replication in the HIP rat.
Journal: American journal of physiology. Endocrinology and metabolism 20090801
Title: How does treatment satisfaction work?: Modeling determinants of treatment satisfaction and preference.
Journal: Diabetes care 20090801
Title: Vaspin and amylin are expressed in human and rat placenta and regulated by nutritional status.
Journal: Histology and histopathology 20090801
Title: Effects of amylin on bone development and egg production in hens.
Journal: Poultry science 20090801
Title: Solution state structures of human pancreatic amylin and pramlintide.
Journal: Protein engineering, design & selection : PEDS 20090801
Title: Elucidating the mechanism of lipid membrane-induced IAPP fibrillogenesis and its inhibition by the red wine compound resveratrol: a synchrotron X-ray reflectivity study.
Journal: Journal of the American Chemical Society 20090715
Title: Phycocyanin protects INS-1E pancreatic beta cells against human islet amyloid polypeptide-induced apoptosis through attenuating oxidative stress and modulating JNK and p38 mitogen-activated protein kinase pathways.
Journal: The international journal of biochemistry & cell biology 20090701
Title: Diet-derived nutrients mediate the inhibition of hypothalamic NPY neurons in the arcuate nucleus of mice during refeeding.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090701
Title: Beneficial endocrine but adverse exocrine effects of sitagliptin in the human islet amyloid polypeptide transgenic rat model of type 2 diabetes: interactions with metformin.
Journal: Diabetes 20090701
Title: Changes in gene expression and morphology of mouse embryonic stem cells on differentiation into insulin-producing cells in vitro and in vivo.
Journal: Diabetes/metabolism research and reviews 20090701
Title: Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process.
Journal: Protein science : a publication of the Protein Society 20090701
Title: Sphingomyelinase dependent apoptosis following treatment of pancreatic beta-cells with amyloid peptides Abeta(1-42) or IAPP.
Journal: Apoptosis : an international journal on programmed cell death 20090701
Title: Amyloidogenic propensities and conformational properties of ProIAPP and IAPP in the presence of lipid bilayer membranes.
Journal: Journal of molecular biology 20090626
Title: Three-dimensional structure and orientation of rat islet amyloid polypeptide protein in a membrane environment by solution NMR spectroscopy.
Journal: Journal of the American Chemical Society 20090617
Title: Sequence and crowding effects in the aggregation of a 10-residue fragment derived from islet amyloid polypeptide.
Journal: Biophysical journal 20090603
Title: Reducing postprandial hyperglycemia with adjuvant premeal pramlintide and postmeal insulin in children with type 1 diabetes mellitus.
Journal: Pediatric diabetes 20090601
Title: Amyloid inhibitors enhance survival of cultured human islets.
Journal: Biochimica et biophysica acta 20090601
Title: Amyloid formation in human IAPP transgenic mouse islets and pancreas, and human pancreas, is not associated with endoplasmic reticulum stress.
Journal: Diabetologia 20090601
Title: Insulin is a kinetic but not a thermodynamic inhibitor of amylin aggregation.
Journal: The FEBS journal 20090601
Title: New therapeutic agents for diabetes mellitus: implications for anesthetic management.
Journal: Anesthesia and analgesia 20090601
Title: [The effects of amylin on the islet beta-cells voltage-gated L-calcium channels in rats].
Journal: Zhonghua nei ke za zhi 20090601
Title: Fluorescence microscopy studies on islet amyloid polypeptide fibrillation at heterogeneous and cellular membrane interfaces and its inhibition by resveratrol.
Journal: FEBS letters 20090506
Title: Twenty-four-hour simultaneous subcutaneous Basal-bolus administration of insulin and amylin in adolescents with type 1 diabetes decreases postprandial hyperglycemia.
Journal: The Journal of clinical endocrinology and metabolism 20090501
Title: Dynamic alpha-helix structure of micelle-bound human amylin.
Journal: The Journal of biological chemistry 20090501
Title: Structure-function relationships in peptoids: recent advances toward deciphering the structural requirements for biological function.
Journal: Organic & biomolecular chemistry 20090421
Title: New potential adjuncts to treatment of children with type 1 diabetes mellitus.
Journal: Pediatric research 20090401
Title: Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis.
Journal: Diabetologia 20090401
Title: Successful versus failed adaptation to high-fat diet-induced insulin resistance: the role of IAPP-induced beta-cell endoplasmic reticulum stress.
Journal: Diabetes 20090401
Title: Common features between diabetes mellitus and Alzheimer's disease.
Journal: Cellular and molecular life sciences : CMLS 20090401
Title: Induction of negative curvature as a mechanism of cell toxicity by amyloidogenic peptides: the case of islet amyloid polypeptide.
Journal: Journal of the American Chemical Society 20090401
Title: Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus.
Journal: Diabetes 20090401
Title: Control of food intake and energy expenditure by amylin-therapeutic implications.
Journal: International journal of obesity (2005) 20090401
Title: Gut peptides in the control of food intake.
Journal: International journal of obesity (2005) 20090401
Title: Minimal reduction in insulin dosage with pramlintide therapy when pretreatment near-normal glycemia is established and square-wave meal bolus is used.
Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20090401
Title: Glucocorticoids may trigger attacks in several types of periodic paralysis.
Journal: Neuromuscular disorders : NMD 20090301
Title: Implications of amylin receptor agonism: integrated neurohormonal mechanisms and therapeutic applications.
Journal: Archives of neurology 20090301
Title: Two-dimensional infrared spectroscopy provides evidence of an intermediate in the membrane-catalyzed assembly of diabetic amyloid.
Journal: The journal of physical chemistry. B 20090226
Title: Inhibiting islet amyloid polypeptide fibril formation by the red wine compound resveratrol.
Journal: Chembiochem : a European journal of chemical biology 20090213
Title: Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells.
Journal: Stem cells (Dayton, Ohio) 20090201
Title: Adoptive transfer of syngeneic bone marrow-derived cells in mice with obesity-induced diabetes: selenoorganic antioxidant ebselen restores stem cell competence.
Journal: The American journal of pathology 20090201
Title: Amyloid formation results in recurrence of hyperglycaemia following transplantation of human IAPP transgenic mouse islets.
Journal: Diabetologia 20090101
Title: Amyloid oligomers in diabetic and nondiabetic human pancreas.
Journal: Translational research : the journal of laboratory and clinical medicine 20090101
Title: Insulin analog therapy: improving the match with physiologic insulin secretion.
Journal: The Journal of the American Osteopathic Association 20090101
Title: Psychometric properties of an instrument for assessing treatment satisfaction associated with pramlintide use.
Journal: The Diabetes educator 20090101
Title: Overlapping double turn conformations adopted by tetrapeptides containing non-coded alpha-amino isobutyric acid (Aib) and formation of tape-like structures through supramolecular helix mediated self-assembly.
Journal: Protein and peptide letters 20090101
Title: [Drug treatment of insulin resistance].
Journal: Revue medicale de Bruxelles 20090101
Title: Continuous subcutaneous pramlintide infusion therapy in patients with type 1 diabetes: observations from a pilot study.
Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20090101
Title: Long-term metabolic and hormonal effects of exenatide on islet transplant recipients with allograft dysfunction.
Journal: Cell transplantation 20090101
Title: The perspectives of adjunctive drugs usage in the treatment of glucose metabolism disturbances in adolescent patients.
Journal: Pediatric endocrinology, diabetes, and metabolism 20090101
Title: Structures of rat and human islet amyloid polypeptide IAPP(1-19) in micelles by NMR spectroscopy.
Journal: Biochemistry 20081202
Title: A single mutation in the nonamyloidogenic region of islet amyloid polypeptide greatly reduces toxicity.
Journal: Biochemistry 20081202
Title: Calcium elevation in mouse pancreatic beta cells evoked by extracellular human islet amyloid polypeptide involves activation of the mechanosensitive ion channel TRPV4.
Journal: Diabetologia 20081201
Title: Gastric emptying and postprandial glucose excursions in adolescents with type 1 diabetes.
Journal: Pediatric diabetes 20081201
Title: Impaired hyperglycemia-induced delay in gastric emptying in patients with type 1 diabetes deficient for islet amyloid polypeptide.
Journal: Diabetes care 20081201
Title: Diabetes distress and its association with clinical outcomes in patients with type 2 diabetes treated with pramlintide as an adjunct to insulin therapy.
Journal: Diabetes technology & therapeutics 20081201
Title: Receptor activity-modifying proteins differentially modulate the G protein-coupling efficiency of amylin receptors.
Journal: Endocrinology 20081101
Title: Amylin-mediated restoration of leptin responsiveness in diet-induced obesity: magnitude and mechanisms.
Journal: Endocrinology 20081101
Title: Polyphenol-induced dissociation of various amyloid fibrils results in a methionine-independent formation of ROS.
Journal: Biochimica et biophysica acta 20081101
Title: Hormone-based therapies in the regulation of fuel metabolism and body weight.
Journal: Expert opinion on biological therapy 20081101
Title: Spontaneous diabetes in hemizygous human amylin transgenic mice that developed neither islet amyloid nor peripheral insulin resistance.
Journal: Diabetes 20081001
Title: Pramlintide reduces the risks associated with glucose variability in type 1 diabetes.
Journal: Diabetes technology & therapeutics 20081001
Title: Interaction of membrane-bound islet amyloid polypeptide with soluble and crystalline insulin.
Journal: Protein science : a publication of the Protein Society 20081001
Title: Amylin proprotein processing generates progressively more amyloidogenic peptides that initially sample the helical state.
Journal: Biochemistry 20080916
Title: Molecular characterization of calcitonin gene-related peptide (CGRP) related peptides (CGRP, amylin, adrenomedullin and adrenomedullin-2/intermedin) in goldfish (Carassius auratus): cloning and distribution.
Journal: Peptides 20080901
Title: Atomic structure of the cross-beta spine of islet amyloid polypeptide (amylin).
Journal: Protein science : a publication of the Protein Society 20080901
Title: Sustained weight loss following 12-month pramlintide treatment as an adjunct to lifestyle intervention in obesity.
Journal: Diabetes care 20080901
Title: Antiobesity effects of the beta-cell hormone amylin in combination with phentermine or sibutramine in diet-induced obese rats.
Journal: International journal of obesity (2005) 20080801
Title: The use of exenatide in islet transplant recipients with chronic allograft dysfunction: safety, efficacy, and metabolic effects.
Journal: Transplantation 20080715
Title: A biophysical characterization of the peptide drug pramlintide (AC137) using empirical phase diagrams.
Journal: Journal of pharmaceutical sciences 20080701
Title: Amylin peptide is increased in preterm neonates with feed intolerance.
Journal: Archives of disease in childhood. Fetal and neonatal edition 20080701
Title: Adrenomedullin-2/intermedin induces cAMP accumulation in dissociated rat spinal cord cells: evidence for the existence of a distinct class of sites of action.
Journal: Journal of molecular neuroscience : MN 20080701
Title: Human but not rat amylin shares neurotoxic properties with Abeta42 in long-term hippocampal and cortical cultures.
Journal: FEBS letters 20080625
Title: The fluorescent amino acid p-cyanophenylalanine provides an intrinsic probe of amyloid formation.
Journal: Chembiochem : a European journal of chemical biology 20080616
Title: Gastric emptying in response to IAPP and CCK in rats with subdiaphragmatic afferent vagotomy.
Journal: Regulatory peptides 20080605
Title: Phenolsulfonphthalein, but not phenolphthalein, inhibits amyloid fibril formation: implications for the modulation of amyloid self-assembly.
Journal: Biochemistry 20080603
Title: Rifampicin does not prevent amyloid fibril formation by human islet amyloid polypeptide but does inhibit fibril thioflavin-T interactions: implications for mechanistic studies of beta-cell death.
Journal: Biochemistry 20080603
Title: Differential responses of circulating amylin to high-fat vs. high-carbohydrate meal in healthy men.
Journal: Clinical endocrinology 20080601
Title: Cleavage agents for soluble oligomers of human islet amyloid polypeptide.
Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080601
Title: Central and peripheral administration of amylin induces energy expenditure in anesthetized rats.
Journal: Peptides 20080601
Title: International Union of Pharmacology. LXIX. Status of the calcitonin gene-related peptide subtype 2 receptor.
Journal: Pharmacological reviews 20080601
Title: Type 2 diabetes: the many facets of care.
Journal: Home healthcare nurse 20080601
Title: Amyloid fiber formation and membrane disruption are separate processes localized in two distinct regions of IAPP, the type-2-diabetes-related peptide.
Journal: Journal of the American Chemical Society 20080521
Title: Leptin responsiveness restored by amylin agonism in diet-induced obesity: evidence from nonclinical and clinical studies.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20080520
Title: Leptin does not directly regulate the pancreatic hormones amylin and pancreatic polypeptide: interventional studies in humans.
Journal: Diabetes care 20080501
Title: Increased secretion and expression of amylin in spontaneously diabetic Goto-Kakizaki rats treated with rhGLP-1 (7-36).
Journal: Acta pharmacologica Sinica 20080501
Title: Managed care perspective on three new agents for type 2 diabetes.
Journal: Journal of managed care pharmacy : JMCP 20080501
Title: Prevention and promotion effects of apolipoprotein E4 on amylin aggregation.
Journal: Biochemical and biophysical research communications 20080404
Title: Sedimentation studies on human amylin fail to detect low-molecular-weight oligomers.
Journal: Biophysical journal 20080401
Title: Differential secretion of satiety hormones with progression of obesity in JCR:LA-corpulent rats.
Journal: Obesity (Silver Spring, Md.) 20080401
Title: Beta-amyloid peptides 1-40betaA and 25-35betaA suppress human amylin-mediated death of RINm5F islet beta-cells with distinct actions on fibril formation.
Journal: Cell biology international 20080401
Title: New treatments of diabetes: the beta-amylin agonists.
Journal: Annales d'endocrinologie 20080401
Title: Pramlintide, the synthetic analogue of amylin: physiology, pathophysiology, and effects on glycemic control, body weight, and selected biomarkers of vascular risk.
Journal: Vascular health and risk management 20080401
Title: Amide inequivalence in the fibrillar assembly of islet amyloid polypeptide.
Journal: Protein engineering, design & selection : PEDS 20080301
Title: [Adjunctive therapies to glycaemic control of type 1 diabetes mellitus].
Journal: Arquivos brasileiros de endocrinologia e metabologia 20080301
Title: Islet amyloid polypeptide forms rigid lipid-protein amyloid fibrils on supported phospholipid bilayers.
Journal: Journal of molecular biology 20080208
Title: Amylin causes anorexigenic effects via the hypothalamus and brain stem in chicks.
Journal: Regulatory peptides 20080207
Title: Pramlintide reduced markers of oxidative stress in the postprandial period in patients with type 2 diabetes.
Journal: Diabetes/metabolism research and reviews 20080201
Title: Fas-associated death receptor signaling evoked by human amylin in islet beta-cells.
Journal: Diabetes 20080201
Title: Copper(II) inhibits the formation of amylin amyloid in vitro.
Journal: Journal of inorganic biochemistry 20080201
Title: Beta-cell apoptosis in type 2 diabetes: quantitative and functional consequences.
Journal: Diabetes & metabolism 20080201
Title: The effects of C-terminal truncation of receptor activity modifying proteins on the induction of amylin receptor phenotype from human CTb receptors.
Journal: Regulatory peptides 20080110
Title: Fast conventional Fmoc solid-phase peptide synthesis with HCTU.
Journal: Journal of peptide science : an official publication of the European Peptide Society 20080101
Title: Clinical experience with the addition of pramlintide in patients with insulin-requiring type 2 diabetes.
Journal: Diabetes care 20080101
Title: Importance of changes in gastric emptying for postprandial plasma glucose fluxes in healthy humans.
Journal: American journal of physiology. Endocrinology and metabolism 20080101
Title: Effect of pramlintide as an adjunct to basal insulin on markers of cardiovascular risk in patients with type 2 diabetes.
Journal: Current medical research and opinion 20080101
Title: Emerging concepts in the medical and surgical treatment of obesity.
Journal: Frontiers of hormone research 20080101
Title: Optimizing diabetes treatment using an amylin analogue.
Journal: The Diabetes educator 20080101
Title: Optimizing treatment success with an amylin analogue.
Journal: The Diabetes educator 20080101
Title: Small-molecule inhibitors of islet amyloid polypeptide fibril formation.
Journal: Angewandte Chemie (International ed. in English) 20080101
Title: Recent insights in islet amyloid polypeptide-induced membrane disruption and its role in beta-cell death in type 2 diabetes mellitus.
Journal: Experimental diabetes research 20080101
Title: Human islet amyloid polypeptide transgenic mice: in vivo and ex vivo models for the role of hIAPP in type 2 diabetes mellitus.
Journal: Experimental diabetes research 20080101
Title: The role of the 14-20 domain of the islet amyloid polypeptide in amyloid formation.
Journal: Experimental diabetes research 20080101
Title: Real-time monitoring of apoptosis by caspase-3-like protease induced FRET reduction triggered by amyloid aggregation.
Journal: Experimental diabetes research 20080101
Title: Disturbed alpha-cell function in mice with beta-cell specific overexpression of human islet amyloid polypeptide.
Journal: Experimental diabetes research 20080101
Title: [Role of amylin in glucose homeostasis and its perspective use in diabetes management].
Journal: Przeglad lekarski 20080101
Title: Transthyretin and amyloid in the islets of Langerhans in type-2 diabetes.
Journal: Experimental diabetes research 20080101
Title: New drugs for type 2 diabetes mellitus: what is their place in therapy?
Journal: Drugs 20080101
Title: [New therapies for diabetes: beyond injectable insulin and oral antidiabetics].
Journal: Revista da Associacao Medica Brasileira (1992) 20080101
Title: Pramlintide in the treatment of diabetes mellitus.
Journal: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20080101
Title: Nano-scale imaging and dynamics of amylin-membrane interactions and its implication in type II diabetes mellitus.
Journal: Methods in cell biology 20080101
Title: Amyloid deposition in transplanted human pancreatic islets: a conceivable cause of their long-term failure.
Journal: Experimental diabetes research 20080101
Title: Importance of aggregated islet amyloid polypeptide for the progressive beta-cell failure in type 2 diabetes and in transplanted human islets.
Journal: Experimental diabetes research 20080101
Title: Desensitization and re-sensitization of CGRP receptor function in human neuroblastoma SK-N-MC cells.
Journal: European journal of pharmacology 20071222
Title: Fast Fmoc synthesis of hAmylin1-37 with pseudoproline assisted on-resin disulfide formation.
Journal: Journal of peptide science : an official publication of the European Peptide Society 20071201
Title: Combination therapy with amylin and peptide YY[3-36] in obese rodents: anorexigenic synergy and weight loss additivity.
Journal: Endocrinology 20071201
Title: Induction of endoplasmic reticulum stress-induced beta-cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide.
Journal: American journal of physiology. Endocrinology and metabolism 20071201
Title: The role of prandial pramlintide in the treatment of adolescents with type 1 diabetes.
Journal: Pediatric research 20071201
Title: Pharmacotherapy for obesity.
Journal: Current atherosclerosis reports 20071201
Title: Peptide conformation and supramolecular organization in amylin fibrils: constraints from solid-state NMR.
Journal: Biochemistry 20071127
Title: In-vitro and in-vivo antagonistic action of an anti-amylin Spiegelmer.
Journal: Neuroreport 20071119
Title: Pramlintide improved glycemic control and reduced weight in patients with type 2 diabetes using basal insulin.
Journal: Diabetes care 20071101
Title: Effects of intermittent intraperitoneal infusion of salmon calcitonin on food intake and adiposity in obese rats.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20071101
Title: Inhibition of glycosaminoglycan synthesis and protein glycosylation with WAS-406 and azaserine result in reduced islet amyloid formation in vitro.
Journal: American journal of physiology. Cell physiology 20071101
Title: Pharmacological actions of the peptide hormone amylin in the long-term regulation of food intake, food preference, and body weight.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20071101
Title: Amyloid formation by pro-islet amyloid polypeptide processing intermediates: examination of the role of protein heparan sulfate interactions and implications for islet amyloid formation in type 2 diabetes.
Journal: Biochemistry 20071030
Title: Insight into antidiabetic therapies: a report from the 43rd annual meeting of the European Association for the Study of Diabetes.
Journal: Timely topics in medicine. Cardiovascular diseases 20071024
Title: DPP-4 inhibition improves glucose tolerance and increases insulin and GLP-1 responses to gastric glucose in association with normalized islet topography in mice with beta-cell-specific overexpression of human islet amyloid polypeptide.
Journal: Regulatory peptides 20071004
Title: Fibrillogenic amylin evokes the apoptosis of human mesangial cells.
Journal: Diabetes research and clinical practice 20071001
Title: Effects of prior or concurrent food restriction on amylin-induced changes in body weight and body composition in high-fat-fed female rats.
Journal: American journal of physiology. Endocrinology and metabolism 20071001
Title: Diabetes mellitus in pancreatic cancer: is it a causal relationship?
Journal: American journal of surgery 20071001
Title: Effects of lactogen resistance and GH deficiency on mouse metabolism: pancreatic hormones, adipocytokines, and expression of adiponectin and insulin receptors.
Journal: Endocrine 20071001
Title: [The regulation of body mass and its relation to the development of obesity].
Journal: Orvosi hetilap 20070930
Title: Histamine H1-receptors differentially mediate the action of amylin on hypothalamic neurons in control and in overweight rats.
Journal: Behavioural brain research 20070822
Title: Modulation of the satiating effect of amylin by central ghrelin, leptin and insulin.
Journal: Physiology & behavior 20070815
Title: Lesion of the lateral parabrachial nucleus attenuates the anorectic effect of peripheral amylin and CCK.
Journal: Brain research 20070808
Title: Progressive reduction in body weight after treatment with the amylin analog pramlintide in obese subjects: a phase 2, randomized, placebo-controlled, dose-escalation study.
Journal: The Journal of clinical endocrinology and metabolism 20070801
Title: Pramlintide treatment reduces 24-h caloric intake and meal sizes and improves control of eating in obese subjects: a 6-wk translational research study.
Journal: American journal of physiology. Endocrinology and metabolism 20070801
Title: Assessing treatment satisfaction in patients treated with pramlintide as an adjunct to insulin therapy.
Journal: Current medical research and opinion 20070801
Title: Amylin and its relation to insulin and lipids in obese children before and after weight loss.
Journal: Obesity (Silver Spring, Md.) 20070801
Title: Type 2 diabetes drug boom: is newer better?
Journal: The Johns Hopkins medical letter health after 50 20070801
Title: Copper-mediated formation of hydrogen peroxide from the amylin peptide: a novel mechanism for degeneration of islet cells in type-2 diabetes mellitus?
Journal: FEBS letters 20070724
Title: Protective effects of amylin on reserpine-induced gastric damage in the rat.
Journal: Pharmacological research 20070701
Title: Pharmacokinetics of an oral drug (acetaminophen) administered at various times relative to subcutaneous injection of pramlintide in subjects with type 2 diabetes.
Journal: Journal of clinical pharmacology 20070701
Title: Agonist-dependent consequences of proline to alanine substitution in the transmembrane helices of the calcitonin receptor.
Journal: British journal of pharmacology 20070701
Title: Amylin deposition in the kidney of patients with diabetic nephropathy.
Journal: Kidney international 20070701
Title: Are you up-to-date on diabetes medications?
Journal: Nursing 20070701
Title: Management of comorbid diabetes and cancer.
Journal: Oncology (Williston Park, N.Y.) 20070701
Title: Therapies for diabetes: pramlintide and exenatide.
Journal: American family physician 20070615
Title: The acute effect of amylin and salmon calcitonin on energy expenditure.
Journal: Physiology & behavior 20070608
Title: Longitudinal ultrastructure study of islet amyloid in the HIP rat model of type 2 diabetes mellitus.
Journal: Experimental biology and medicine (Maywood, N.J.) 20070601
Title: Cloning and expression of human islet amyloid polypeptide in cultured cells.
Journal: Biochemical and biophysical research communications 20070511
Title: Toxic human islet amyloid polypeptide (h-IAPP) oligomers are intracellular, and vaccination to induce anti-toxic oligomer antibodies does not prevent h-IAPP-induced beta-cell apoptosis in h-IAPP transgenic mice.
Journal: Diabetes 20070501
Title: Is pramlintide a safe and effective adjunct therapy for patients with type 1 diabetes?
Journal: Nature clinical practice. Endocrinology & metabolism 20070501
Title: Low-dose pramlintide reduced food intake and meal duration in healthy, normal-weight subjects.
Journal: Obesity (Silver Spring, Md.) 20070501
Title: Amylin S20G mutation in Mexican population.
Journal: Diabetes research and clinical practice 20070401
Title: Amylin and hypertension: association of an amylin -G132A gene mutation and hypertension in humans and amylin-induced endothelium dysfunction in rats.
Journal: The Journal of clinical endocrinology and metabolism 20070401
Title: Transformation of the amyloidogenic peptide amylin(20-29) into its corresponding peptoid and retropeptoid: access to both an amyloid inhibitor and template for self-assembled supramolecular tapes.
Journal: Bioorganic & medicinal chemistry letters 20070401
Title: Pramlintide as an adjunct to insulin in patients with type 2 diabetes in a clinical practice setting reduced A1C, postprandial glucose excursions, and weight.
Journal: Diabetes technology & therapeutics 20070401
Title: New drugs for the treatment of type 2 diabetes.
Journal: British journal of hospital medicine (London, England : 2005) 20070401
Title: Pramlintide acetate injection for the treatment of type 1 and type 2 diabetes mellitus.
Journal: Clinical therapeutics 20070401
Title: Aromatic interactions are not required for amyloid fibril formation by islet amyloid polypeptide but do influence the rate of fibril formation and fibril morphology.
Journal: Biochemistry 20070320
Title: Inhibitory effect of BIBN4096BS, CGRP(8-37), a CGRP antibody and an RNA-Spiegelmer on CGRP induced vasodilatation in the perfused and non-perfused rat middle cerebral artery.
Journal: British journal of pharmacology 20070301
Title: Diabetes drug update: how 4 new options stack up.
Journal: The Journal of family practice 20070301
Title: Leapin' lizards: Amylin targets diabetes and obesity via incretins.
Journal: Chemistry & biology 20070301
Title: Selective desulfurization of cysteine in the presence of Cys(Acm) in polypeptides obtained by native chemical ligation.
Journal: Organic letters 20070215
Title: Through the looking glass: current and future perspectives on the role of hormonal interplay in glucose homeostasis.
Journal: The Diabetes educator 20070201
Title: Direct detection of transient alpha-helical states in islet amyloid polypeptide.
Journal: Protein science : a publication of the Protein Society 20070101
Title: Neuropeptides of the islets of Langerhans: a peptidomics study.
Journal: General and comparative endocrinology 20070101
Title: Diet-derived nutrients modulate the effects of amylin on c-Fos expression in the area postrema and on food intake.
Journal: Neuroendocrinology 20070101
Title: Pharmacologic management of type 1 diabetes: a review for dentistry.
Journal: General dentistry 20070101
Title: Environmental factors differently affect human and rat IAPP: conformational preferences and membrane interactions of IAPP17-29 peptide derivatives.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20070101
Title: Bodyweight changes associated with antihyperglycaemic agents in type 2 diabetes mellitus.
Journal: Drug safety 20070101
Title: New therapies for diabetes.
Journal: Clinical cornerstone 20070101
Title: Role of endogenous amylin in glucagon secretion and gastric emptying in rats demonstrated with the selective antagonist, AC187.
Journal: Regulatory peptides 20061210
Title: Role of neuropeptides in appetite regulation and obesity--a review.
Journal: Neuropeptides 20061201
Title: Antiobesity effects of the beta-cell hormone amylin in diet-induced obese rats: effects on food intake, body weight, composition, energy expenditure, and gene expression.
Journal: Endocrinology 20061201
Title: An in vitro model of early islet amyloid polypeptide (IAPP) fibrillogenesis using human IAPP-transgenic mouse islets.
Journal: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20061201
Title: A novel analytical method for assessing glucose variability: using CGMS in type 1 diabetes mellitus.
Journal: Diabetes technology & therapeutics 20061201
Title: Pramlintide in the treatment of diabetes.
Journal: International journal of clinical practice 20061201
Title: Amylinergic control of food intake.
Journal: Physiology & behavior 20061130
Title: The role of amylin and related peptides in osteoporosis.
Journal: Clinica chimica acta; international journal of clinical chemistry 20061101
Title: Kinectin participates in microtubule-dependent hormone secretion in pancreatic islet beta-cells.
Journal: Cell biology international 20061101
Title: Clinical features and morphological characterization of 10 patients with noninsulinoma pancreatogenous hypoglycaemia syndrome (NIPHS).
Journal: Clinical endocrinology 20061101
Title: Adjunctive therapy with pramlintide in patients with type 1 or type 2 diabetes mellitus.
Journal: Pharmacotherapy 20061101
Title: Pramlintide: A new tool in diabetes management.
Journal: Current diabetes reports 20061101
Title: Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism.
Journal: Nature 20061019
Title: Synthesis and structural investigations of N-alkylated beta-peptidosulfonamide-peptide hybrids of the amyloidogenic amylin(20-29) sequence: Implications of supramolecular folding for the design of peptide-based bionanomaterials.
Journal: Organic & biomolecular chemistry 20061007
Title: Bombesin, but not amylin, blocks the orexigenic effect of peripheral ghrelin.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20061001
Title: A double-blind, placebo-controlled trial assessing pramlintide treatment in the setting of intensive insulin therapy in type 1 diabetes.
Journal: Diabetes care 20061001
Title: Pramlintide in the management of insulin-using patients with type 2 and type 1 diabetes.
Journal: Vascular health and risk management 20060901
Title: Activation of activating transcription factor 2 by p38 MAP kinase during apoptosis induced by human amylin in cultured pancreatic beta-cells.
Journal: The FEBS journal 20060801
Title: The aggregation potential of human amylin determines its cytotoxicity towards islet beta-cells.
Journal: The FEBS journal 20060801
Title: The vasorelaxant effect of adrenomedullin, proadrenomedullin N-terminal 20 peptide and amylin in human skin.
Journal: Basic & clinical pharmacology & toxicology 20060801
Title: Pancreatic signals controlling food intake; insulin, glucagon and amylin.
Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20060729
Title: New diabetes drugs target gut hormones.
Journal: JAMA 20060726
Title: The role of neuropeptide Y, orexins, cocaine and amphetamine-related transcript, cholecystokinin, amylin and leptin in the regulation of feeding in fish.
Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20060701
Title: Beta-cell deficit due to increased apoptosis in the human islet amyloid polypeptide transgenic (HIP) rat recapitulates the metabolic defects present in type 2 diabetes.
Journal: Diabetes 20060701
Title: The organization of aromatic side groups in an amyloid fibril probed by solid-state 2H and 19F NMR spectroscopy.
Journal: Journal of the American Chemical Society 20060628
Title: Effects of amylin deficiency on trabecular bone in young mice are sex-dependent.
Journal: Calcified tissue international 20060601
Title: Increased plasma amylin in type 1 diabetic patients after kidney and pancreas transplantation: A sign of impaired beta-cell function?
Journal: Diabetes care 20060501
Title: Exenatide and pramlintide: new glucose-lowering agents for treating diabetes mellitus.
Journal: Cleveland Clinic journal of medicine 20060501
Title: What's new in clinical pharmacology and therapeutics.
Journal: WMJ : official publication of the State Medical Society of Wisconsin 20060501
Title: Recovery and purification of highly aggregation-prone disulfide-containing peptides: application to islet amyloid polypeptide.
Journal: Analytical biochemistry 20060415
Title: Binding of trypsin to fibrillar amyloid beta-protein.
Journal: Brain research 20060412
Title: A molecular dynamics approach to the structural characterization of amyloid aggregation.
Journal: Journal of molecular biology 20060407
Title: Diabetes: assessing the pipeline.
Journal: Atherosclerosis. Supplements 20060401
Title: Obesity drugs in clinical development.
Journal: Current opinion in investigational drugs (London, England : 2000) 20060401
Title: Newer therapeutic options for children with diabetes mellitus: theoretical and practical considerations.
Journal: Pediatric diabetes 20060401
Title: Practical considerations of new drugs: new choices for old problems.
Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20060401
Title: GABAA receptor antagonists prevent abnormalities in leptin, insulin and amylin actions on paraventricular hypothalamic neurons of overweight rats.
Journal: The European journal of neuroscience 20060301
Title: Emerging therapies mimicking the effects of amylin and glucagon-like peptide 1.
Journal: Diabetes care 20060201
Title: A look back at the most influential drug approvals of 2005.
Journal: The Nurse practitioner 20060201
Title: New drugs 06, part I.
Journal: Nursing 20060201
Title: Molecular structure of amyloid fibrils: insights from solid-state NMR.
Journal: Quarterly reviews of biophysics 20060201
Title: Effects of amylin on feeding of goldfish: interactions with CCK.
Journal: Regulatory peptides 20060115
Title: Destabilization of human IAPP amyloid fibrils by proline mutations outside of the putative amyloidogenic domain: is there a critical amyloidogenic domain in human IAPP?
Journal: Journal of molecular biology 20060113
Title: Role of islet amyloid in type 2 diabetes mellitus.
Journal: The international journal of biochemistry & cell biology 20060101
Title: Why does diabetes mellitus increase the risk of cardiovascular disease?
Journal: Acta medica Indonesiana 20060101
Title: New insights into glucose regulation.
Journal: The Diabetes educator 20060101
Title: Therapeutic options in development for management of diabetes: pharmacologic agents and new technologies.
Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20060101
Title: Deletions of genes encoding calcitonin/alpha-CGRP, amylin and calcitonin receptor have given new and unexpected insights into the function of calcitonin receptors and calcitonin receptor-like receptors in bone.
Journal: Journal of musculoskeletal & neuronal interactions 20060101
Title: The physiology of amylin and insulin: maintaining the balance between glucose secretion and glucose uptake.
Journal: The Diabetes educator 20060101
Title: Amylin replacement therapy in patients with insulin-requiring type 2 diabetes.
Journal: The Diabetes educator 20060101
Title: Use of pramlintide: the patient's perspective.
Journal: The Diabetes educator 20060101
Title: Amylin replacement therapy in patients with type 1 diabetes.
Journal: The Diabetes educator 20060101
Title: Islet amyloid polypeptide (IAPP) transgenic rodents as models for type 2 diabetes.
Journal: ILAR journal 20060101
Title: Diabetes basics. Exenatide and pramlintide. New meds on the block.
Journal: Diabetes self-management 20060101
Title: Update in the pharmacologic treatment of diabetes mellitus: focus on pramlintide and exenatide.
Journal: The Diabetes educator 20060101
Title: Amylin in the periphery II: An updated mini-review.
Journal: TheScientificWorldJournal 20060101
Title: The role of His-18 in amyloid formation by human islet amyloid polypeptide.
Journal: Biochemistry 20051213
Title: Amylin peptide levels are raised in infants of diabetic mothers.
Journal: Archives of disease in childhood 20051201
Title: Activation of peroxisome proliferator-activated receptor-gamma by rosiglitazone protects human islet cells against human islet amyloid polypeptide toxicity by a phosphatidylinositol 3'-kinase-dependent pathway.
Journal: The Journal of clinical endocrinology and metabolism 20051201
Title: Insulin analogues in children and teens with type 1 diabetes: advantages and caveats.
Journal: Pediatric clinics of North America 20051201
Title: Effect of amylin on prolactin release.
Journal: Neuro endocrinology letters 20051201
Title: Quantifying temporal glucose variability in diabetes via continuous glucose monitoring: mathematical methods and clinical application.
Journal: Diabetes technology & therapeutics 20051201
Title: Pramlintide acetate.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20051115
Title: Reduced ghrelin, islet amyloid polypeptide, and peptide YY expression in the stomach of gastrin-cholecystokinin knockout mice.
Journal: Endocrinology 20051001
Title: Thiol reducing compounds prevent human amylin-evoked cytotoxicity.
Journal: The FEBS journal 20051001
Title: Day-long subcutaneous infusion of exenatide lowers glycemia in patients with type 2 diabetes.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20051001
Title: Pramlintide in the treatment of type 1 and type 2 diabetes mellitus.
Journal: Clinical therapeutics 20051001
Title: Selective nucleotide-release from dense-core granules in insulin-secreting cells.
Journal: Journal of cell science 20050915
Title: Lipid membranes modulate the structure of islet amyloid polypeptide.
Journal: Biochemistry 20050913
Title: The effect of pramlintide on hormonal, metabolic or symptomatic responses to insulin-induced hypoglycaemia in patients with type 1 diabetes.
Journal: Diabetes, obesity & metabolism 20050901
Title: Pharmaceutical liquid crystals: the relevance of partially ordered systems.
Journal: Journal of pharmaceutical sciences 20050901
Title: Potential role of pancreatic and enteric hormones in regulating bone turnover.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20050901
Title: Amylin induces natriuresis by a central angiotensin-dependent mechanism.
Journal: Regulatory peptides 20050815
Title: Dose-response for inhibition by amylin of cholecystokinin-stimulated secretion of amylase and lipase in rats.
Journal: Regulatory peptides 20050815
Title: Enterostatin decreases postprandial pancreatic UCP2 mRNA levels and increases plasma insulin and amylin.
Journal: American journal of physiology. Endocrinology and metabolism 20050701
Title: Long-term treatment with rosiglitazone and metformin reduces the extent of, but does not prevent, islet amyloid deposition in mice expressing the gene for human islet amyloid polypeptide.
Journal: Diabetes 20050701
Title: Presence and function of the calcitonin gene-related peptide receptor on rat pial arteries investigated in vitro and in vivo.
Journal: Cephalalgia : an international journal of headache 20050601
Title: Pramlintide (symlin) for diabetes.
Journal: The Medical letter on drugs and therapeutics 20050523
Title: Effect of pramlintide on satiety and food intake in obese subjects and subjects with type 2 diabetes.
Journal: Diabetologia 20050501
Title: The parallel superpleated beta-structure as a model for amyloid fibrils of human amylin.
Journal: Journal of molecular biology 20050429
Title: Properties of pramlintide and insulin upon mixing.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050415
Title: The role of amylin and glucagon in the dampening of glycemic excursions in children with type 1 diabetes.
Journal: Diabetes 20050401
Title: Adjunctive therapy with pramlintide lowers HbA1c without concomitant weight gain and increased risk of severe hypoglycemia in patients with type 1 diabetes approaching glycemic targets.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20050401
Title: Effects of pramlintide on postprandial glucose excursions and measures of oxidative stress in patients with type 1 diabetes.
Journal: Diabetes care 20050301
Title: Pancreatic amylin as a centrally acting satiating hormone.
Journal: Current drug targets 20050301
Title: Incorporation of pseudoproline derivatives allows the facile synthesis of human IAPP, a highly amyloidogenic and aggregation-prone polypeptide.
Journal: Organic letters 20050217
Title: Nucleation-dependent polymerization is an essential component of amyloid-mediated neuronal cell death.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050202
Title: [S20G mutation of amylin gene--amyloid diabetes due to S20G amylin gene mutation].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050201
Title: The regulation of amylin and insulin gene expression and secretion.
Journal: Pancreas 20050101
Title: Chronically administered islet amyloid polypeptide in rats serves as an adiposity inhibitor and regulates energy homeostasis.
Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20050101
Title: Time-lapse atomic force microscopy in the characterization of amyloid-like fibril assembly and oligomeric intermediates.
Journal: Methods in molecular biology (Clifton, N.J.) 20050101
Title: New methods for researching accessory proteins.
Journal: Journal of molecular neuroscience : MN 20050101
Title: Amylin. Insulin's partner.
Journal: Diabetes self-management 20050101
Title: New drugs: exenatide, pramlintide acetate, and micafungin sodium.
Journal: Journal of the American Pharmacists Association : JAPhA 20050101
Title: Tissue expression and secretion of amylin.
Journal: Advances in pharmacology (San Diego, Calif.) 20050101
Title: Amylin and the integrated control of nutrient influx.
Journal: Advances in pharmacology (San Diego, Calif.) 20050101
Title: Inhibition of food intake.
Journal: Advances in pharmacology (San Diego, Calif.) 20050101
Title: Inhibition of gastric emptying.
Journal: Advances in pharmacology (San Diego, Calif.) 20050101
Title: Effects on digestive secretions.
Journal: Advances in pharmacology (San Diego, Calif.) 20050101
Title: Inhibition of glucagon secretion.
Journal: Advances in pharmacology (San Diego, Calif.) 20050101
Title: Inhibition of insulin secretion.
Journal: Advances in pharmacology (San Diego, Calif.) 20050101
Title: Effects on plasma glucose and lactate.
Journal: Advances in pharmacology (San Diego, Calif.) 20050101
Title: Effects in skeletal muscle.
Journal: Advances in pharmacology (San Diego, Calif.) 20050101
Title: Effects in liver.
Journal: Advances in pharmacology (San Diego, Calif.) 20050101
Title: Effects in fat.
Journal: Advances in pharmacology (San Diego, Calif.) 20050101
Title: Cardiovascular effects.
Journal: Advances in pharmacology (San Diego, Calif.) 20050101
Title: Renal effects.
Journal: Advances in pharmacology (San Diego, Calif.) 20050101
Title: Effects on bone.
Journal: Advances in pharmacology (San Diego, Calif.) 20050101
Title: Central nervous system and other effects.
Journal: Advances in pharmacology (San Diego, Calif.) 20050101
Title: Clinical studies.
Journal: Advances in pharmacology (San Diego, Calif.) 20050101
Title: Arcuate neurons of overweight rats differ in their responses to amylin from controls.
Journal: Neuroreport 20041222
Title: Role of aromatic interactions in amyloid formation by peptides derived from human Amylin.
Journal: Biochemistry 20041221
Title: Amylin agonists: a novel approach in the treatment of diabetes.
Journal: Diabetes 20041201
Title: GSK3 involvement in amylin signaling in isolated rat soleus muscle.
Journal: Peptides 20041201
Title: Transcriptional regulation of the IAPP gene in pancreatic beta-cells.
Journal: Biochimica et biophysica acta 20041124
Title: Inhibition of islet amyloid polypeptide fibril formation: a potential role for heteroaromatic interactions.
Journal: Biochemistry 20041116
Title: Identifying structural features of fibrillar islet amyloid polypeptide using site-directed spin labeling.
Journal: The Journal of biological chemistry 20041112
Title: Amylin replacement with pramlintide as an adjunct to insulin therapy improves long-term glycaemic and weight control in Type 1 diabetes mellitus: a 1-year, randomized controlled trial.
Journal: Diabetic medicine : a journal of the British Diabetic Association 20041101
Title: Amyloidogenicity and cytotoxicity of recombinant mature human islet amyloid polypeptide (rhIAPP).
Journal: The Journal of biological chemistry 20041008
Title: Intermedin, a novel calcitonin family peptide that exists in teleosts as well as in mammals: a comparison with other calcitonin/intermedin family peptides in vertebrates.
Journal: Peptides 20041001
Title: Atomic force microscopy reveals defects within mica supported lipid bilayers induced by the amyloidogenic human amylin peptide.
Journal: Journal of molecular biology 20040917
Title: Amylin receptor blockade stimulates food intake in rats.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20040901
Title: Effect of pramlintide on symptom, catecholamine, and glucagon responses to hypoglycemia in healthy subjects.
Journal: Metabolism: clinical and experimental 20040901
Title: Phospholipid catalysis of diabetic amyloid assembly.
Journal: Journal of molecular biology 20040827
Title: Islet amyloid: a critical entity in the pathogenesis of type 2 diabetes.
Journal: The Journal of clinical endocrinology and metabolism 20040801
Title: Mutation at position -132 in the islet amyloid polypeptide ( IAPP) gene promoter enhances basal transcriptional activity through a new CRE-like binding site.
Journal: Diabetologia 20040701
Title: American Diabetes Association--64th Scientific Sessions. Targeting amylin. 4-8 June 2004, Orlando, FL, USA.
Journal: IDrugs : the investigational drugs journal 20040701
Title: In vitro autoradiographic localization of calcitonin and amylin binding sites in monkey brain.
Journal: Journal of chemical neuroanatomy 20040701
Title: Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes.
Journal: Diabetes 20040601
Title: Ghrelin and other glucoregulatory hormone responses to eccentric and concentric muscle contractions.
Journal: Endocrine 20040601
Title: Shared pathways of osteoblast mitogenesis induced by amylin, adrenomedullin, and IGF-1.
Journal: Biochemical and biophysical research communications 20040521
Title: Chronic infusion of the amylin antagonist AC 187 increases feeding in Zucker fa/fa rats but not in lean controls.
Journal: Physiology & behavior 20040501
Title: Seeding specificity in amyloid growth induced by heterologous fibrils.
Journal: The Journal of biological chemistry 20040423
Title: Effect of pramlintide on weight in overweight and obese insulin-treated type 2 diabetes patients.
Journal: Obesity research 20040401
Title: Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation.
Journal: The Journal of biological chemistry 20040326
Title: Amylin-induced suppression of ANP secretion through receptors for CGRP1 and salmon calcitonin.
Journal: Regulatory peptides 20040315
Title: Amylin fasting plasma levels are decreased in patients with osteoporosis.
Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20040301
Title: Extended life span is associated with insulin resistance in a transgenic mouse model of insulinoma secreting human islet amyloid polypeptide.
Journal: American journal of physiology. Endocrinology and metabolism 20040301
Title: Peptide sequence and amyloid formation; molecular simulations and experimental study of a human islet amyloid polypeptide fragment and its analogs.
Journal: Structure (London, England : 1993) 20040301
Title: Post-partum evaluation of amylin in lean patients with gestational diabetes mellitus.
Journal: Acta diabetologica 20040301
Title: Infusion of the amylin antagonist AC 187 into the area postrema increases food intake in rats.
Journal: Physiology & behavior 20040301
Title: ABri peptide associated with familial British dementia forms annular and ring-like protofibrillar structures.
Journal: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20040301
Title: Augmenting with amylin.
Journal: Science of aging knowledge environment : SAGE KE 20040218
Title: Pancreatic beta-cell granule peptides form heteromolecular complexes which inhibit islet amyloid polypeptide fibril formation.
Journal: The Biochemical journal 20040201
Title: Islet amyloid: a complication of islet dysfunction or an aetiological factor in Type 2 diabetes?
Journal: Diabetologia 20040201
Title: Increased risk of type 2 diabetes in Alzheimer disease.
Journal: Diabetes 20040201
Title: Aggregation of liposomes induced by the toxic peptides Alzheimer's Abetas, human amylin and prion (106-126): facilitation by membrane-bound GM1 ganglioside.
Journal: Peptides 20040201
Title: Peripheral amylin activates circumventricular organs expressing calcitonin receptor a/b subtypes and receptor-activity modifying proteins in the rat.
Journal: Brain research 20040130
Title: Structural characterisation of islet amyloid polypeptide fibrils.
Journal: Journal of molecular biology 20040130
Title: Calcitonin gene-related peptide-induced suppression of atrial natriuretic peptide release through receptors for CGRP1 but not for calcitonin and amylin.
Journal: European journal of pharmacology 20040112
Title: The mechanism of insulin action on islet amyloid polypeptide fiber formation.
Journal: Journal of molecular biology 20040102
Title: The anorectic hormone amylin contributes to feeding-related changes of neuronal activity in key structures of the gut-brain axis.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20040101
Title: Pramlintide reduces postprandial glucose excursions when added to insulin lispro in subjects with type 2 diabetes: a dose-timing study.
Journal: Diabetes/metabolism research and reviews 20040101
Title: Neuropeptides and gastric mucosal homeostasis.
Journal: Current topics in medicinal chemistry 20040101
Title: Pramlintide for the treatment of insulin-requiring diabetes mellitus: rationale and review of clinical data.
Journal: Drugs 20040101
Title: Method for measuring neurotoxicity of aggregating polypeptides with the MTT assay on differentiated neuroblastoma cells.
Journal: Brain research bulletin 20031230
Title: Fibrillogenic amylin evokes islet beta-cell apoptosis through linked activation of a caspase cascade and JNK1.
Journal: The Journal of biological chemistry 20031226
Title: -To: Poa NR, Cooper GJS, Edgar PF: Amylin gene promoter mutations predispose to Type 2 diabetes in New Zealand Maori. Diabetologia 46: 574-578.
Journal: Diabetologia 20031201
Title: Effect of pramlintide on A1C and body weight in insulin-treated African Americans and Hispanics with type 2 diabetes: a pooled post hoc analysis.
Journal: Metabolism: clinical and experimental 20031201
Title: Amylin competes for binding sites of CGRP in the chamber angle and uvea of monkey, cat, and pig eye.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20031201
Title: Ex vivo human placental transfer of the peptides pramlintide and exenatide (synthetic exendin-4).
Journal: Human & experimental toxicology 20031201
Title: Amylin gene expression mediated by cAMP/PKA and transcription factors HNF-1 and NFY.
Journal: Molecular and cellular endocrinology 20031128
Title: Pramlintide reduces postprandial glucose excursions when added to regular insulin or insulin lispro in subjects with type 1 diabetes: a dose-timing study.
Journal: Diabetes care 20031101
Title: Prevalence and clinicopathological characteristics of islet amyloid in chinese patients with type 2 diabetes.
Journal: Diabetes 20031101
Title: Addition of pramlintide to insulin therapy lowers HbA1c in conjunction with weight loss in patients with type 2 diabetes approaching glycaemic targets.
Journal: Diabetes, obesity & metabolism 20031101
Title: Involvement of calcitonin gene-related peptide in elevation of skin temperature in castrated male rats.
Journal: Urology 20031101
Title: Hepatocyte nuclear factor 1 negatively regulates amylin gene expression.
Journal: Biochemical and biophysical research communications 20031017
Title: Suppression by polycyclic compounds of the conversion of human amylin into insoluble amyloid.
Journal: The Biochemical journal 20030915
Title: Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid.
Journal: Diabetes 20030901
Title: An insulin-degrading enzyme inhibitor decreases amylin degradation, increases amylin-induced cytotoxicity, and increases amyloid formation in insulinoma cell cultures.
Journal: Diabetes 20030901
Title: [Experimental study of amylin-induced functional damage to rat pancreatic islet cells in vitro].
Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030901
Title: Amylin in pancreatic islets and pancreatic endocrine neoplasms.
Journal: Pathology international 20030901
Title: Beneficial effects of insulin versus sulphonylurea on insulin secretion and metabolic control in recently diagnosed type 2 diabetic patients.
Journal: Diabetes care 20030801
Title: American Diabetes Association--63rd Scientific Sessions. Clinical data. 13-17 June 2003, New Orleans, LA, USA.
Journal: IDrugs : the investigational drugs journal 20030801
Title: Mercury contamination of rat amylin mimics vasoactivity and cytotoxic effects.
Journal: Peptides 20030801
Title: Human amylin actions on rat cholinergic basal forebrain neurons: antagonism of beta-amyloid effects.
Journal: Journal of neurophysiology 20030601
Title: Phlorizin treatment prevents the decrease in plasma insulin levels but not the progressive histopathological changes in the pancreatic islets during aging of Zucker diabetic fatty rats.
Journal: Journal of endocrinological investigation 20030601
Title: Postnatally disturbed pancreatic islet cell distribution in human islet amyloid polypeptide transgenic mice.
Journal: Regulatory peptides 20030515
Title: Proteoglycans synthesized and secreted by pancreatic islet beta-cells bind amylin.
Journal: Archives of biochemistry and biophysics 20030515
Title: Differential effects of amylin and salmon calcitonin on neuropeptide gene expression in the lateral hypothalamic area and the arcuate nucleus of the rat.
Journal: Neuroscience letters 20030501
Title: S20G mutation of the amylin gene is associated with a lower body mass index in Korean type 2 diabetic patients.
Journal: Diabetes research and clinical practice 20030501
Title: Conformational preferences of the amylin nucleation site in SDS micelles: an NMR study.
Journal: Biopolymers 20030501
Title: Inverse relation between amylin and glucagon secretion in healthy and diabetic human subjects.
Journal: European journal of clinical investigation 20030401
Title: Islet amyloid polypeptide and type 2 diabetes.
Journal: Experimental gerontology 20030401
Title: Amylin gene promoter mutations predispose to Type 2 diabetes in New Zealand Maori.
Journal: Diabetologia 20030401
Title: Islet amyloid polypeptide inhibits glucagon release and exerts a dual action on insulin release from isolated islets.
Journal: Regulatory peptides 20030328
Title: Human osteoblast-like cell proliferation induced by calcitonin-related peptides involves PKC activity.
Journal: American journal of physiology. Endocrinology and metabolism 20030301
Title: Short peptide amyloid organization: stabilities and conformations of the islet amyloid peptide NFGAIL.
Journal: Biophysical journal 20030301
Title: Pramlintide as an adjunct to insulin therapy improves long-term glycemic and weight control in patients with type 2 diabetes: a 1-year randomized controlled trial.
Journal: Diabetes care 20030301
Title: Full-length rat amylin forms fibrils following substitution of single residues from human amylin.
Journal: Journal of molecular biology 20030227
Title: Increased dietary fat promotes islet amyloid formation and beta-cell secretory dysfunction in a transgenic mouse model of islet amyloid.
Journal: Diabetes 20030201
Title: Aspirin and diabetes: inhibition of amylin aggregation by nonsteroidal anti-inflammatory drugs.
Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20030201
Title: Specificity of porcine calcitonin receptor and calcitonin receptor-like receptor in the presence of receptor-activity-modifying proteins.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20030201
Title: Calcitonin receptor isoforms expressed in the developing rat kidney.
Journal: Kidney international 20030201
Title: Amylin in human pancreatic islets.
Journal: Pathology 20030201
Title: Transcription factor occupancy of the insulin gene in vivo. Evidence for direct regulation by Nkx2.2.
Journal: The Journal of biological chemistry 20030110
Title: Investigation of CGRP receptors and peptide pharmacology in human coronary arteries. Characterization with a nonpeptide antagonist.
Journal: The Journal of pharmacology and experimental therapeutics 20030101
Title: Impact of pramlintide on glucose fluctuations and postprandial glucose, glucagon, and triglyceride excursions among patients with type 1 diabetes intensively treated with insulin pumps.
Journal: Diabetes care 20030101
Title: Pramlintide: (AC 137, AC 0137, Symlin, Tripro-Amylin).
Journal: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20030101
Title: Endogenous amylin contributes to the anorectic effects of cholecystokinin and bombesin.
Journal: Peptides 20030101
Title: Histamine H1 receptors in the ventromedial hypothalamus mediate the anorectic action of the pancreatic hormone amylin.
Journal: Peptides 20030101
Title: Elevated fasting plasma level of islet amyloid polypeptide (IAPP) in chronic alcoholic pancreatitis (CAP).
Journal: Hepato-gastroenterology 20030101
Title: The effect of apolipoprotein E deficiency on islet amyloid deposition in human islet amyloid polypeptide transgenic mice.
Journal: Diabetologia 20030101
Title: Central amylin signaling and the regulation of energy homeostasis.
Journal: Current pharmaceutical design 20030101
Title: For parents. Type 1 diabetes research. Balancing hope with realism.
Journal: Diabetes self-management 20030101
Title: Amylin in the periphery.
Journal: TheScientificWorldJournal 20030101
Title: Pramlintide for the treatment of diabetes mellitus.
Journal: The Annals of pharmacotherapy 20030101
Title: [Amylin--a partner hormone to insulin].
Journal: Medicinski arhiv 20030101
Title: [New regulatory peptides in rat stomach secretion (amylin, PGP, semax)].
Journal: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20030101
Title: Regulation of amylin release from cultured rabbit gastric fundic mucosal cells.
Journal: BMC physiology 20030101
Title: Immunohistochemical localization of amylin in human pancreas, thyroid, pituitary and their tumors.
Journal: Acta histochemica 20030101
Title: Weight effect of current and experimental drugs for diabetes mellitus: from promotion to alleviation of obesity.
Journal: Treatments in endocrinology 20030101
Title: Effects of free fatty acid on polymerization of islet amyloid polypeptide (IAPP) in vitro and on amyloid fibril formation in cultivated isolated islets of transgenic mice overexpressing human IAPP.
Journal: Molecular medicine (Cambridge, Mass.) 20021201
Title: [Amylin--its physiological role in humans].
Journal: Ceskoslovenska fysiologie 20021201
Title: Pathogenesis of feline diabetes mellitus.
Journal: Molecular and cellular endocrinology 20021129
Title: Increased expression and activation of c-Jun contributes to human amylin-induced apoptosis in pancreatic islet beta-cells.
Journal: Journal of molecular biology 20021122
Title: Effects of ghrelin and amylin on dopamine, norepinephrine and serotonin release in the hypothalamus.
Journal: European journal of pharmacology 20021115
Title: Amylin-induced cytotoxicity is associated with activation of caspase-3 and MAP kinases.
Journal: Biological chemistry 20021101
Title: Polymorphism in intron 2 of islet amyloid polypeptide gene is associated with lower low-density lipoprotein cholesterol in nondiabetic subjects and in type 2 diabetic patients.
Journal: Endocrine 20021101
Title: Amylin, food intake, and obesity.
Journal: Obesity research 20021001
Title: Localization of a fibrillar amyloid beta-protein binding domain on its precursor.
Journal: The Journal of biological chemistry 20020927
Title: Inhibition of amyloid fibril formation of human amylin by N-alkylated amino acid and alpha-hydroxy acid residue containing peptides.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20020916
Title: Oligonucleotide microarray analysis of intact human pancreatic islets: identification of glucose-responsive genes and a highly regulated TGFbeta signaling pathway.
Journal: Endocrinology 20020901
Title: Anti-diabetogenic effect of the human amylin analogue, pramlintide, in Type 1 diabetes is not mediated by GLP-1.
Journal: Diabetic medicine : a journal of the British Diabetic Association 20020901
Title: Islet amyloid, metabolic syndrome, and the natural progressive history of type 2 diabetes mellitus.
Journal: JOP : Journal of the pancreas 20020901
Title: The human amylin analog, pramlintide, reduces postprandial hyperglucagonemia in patients with type 2 diabetes mellitus.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020901
Title: [Diagnostic use of gene polymorphism for type 2 diabetes].
Journal: Rinsho byori. The Japanese journal of clinical pathology 20020901
Title: Amylin and glucose co-activate area postrema neurons of the rat.
Journal: Neuroscience letters 20020809
Title: Expression pattern of IAPP and prohormone convertase 1/3 reveals a distinctive set of endocrine cells in the embryonic pancreas.
Journal: Mechanisms of development 20020701
Title: Estrogen can prevent or reverse obesity and diabetes in mice expressing human islet amyloid polypeptide.
Journal: Diabetes 20020701
Title: Amylin, released from the gastric fundus, stimulates somatostatin and thus inhibits histamine and acid secretion in mice.
Journal: Gastroenterology 20020701
Title: Islet redox stress: the manifold toxicities of insulin resistance, metabolic syndrome and amylin derived islet amyloid in type 2 diabetes mellitus.
Journal: JOP : Journal of the pancreas 20020701
Title: [Secretion and metabolism of insulin].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20020701
Title: [Amylin].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20020701
Title: [Mutation of amylin (IAPP) gene].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20020701
Title: The human amylin analog, pramlintide, corrects postprandial hyperglucagonemia in patients with type 1 diabetes.
Journal: Metabolism: clinical and experimental 20020501
Title: Glucoregulatory endocrine responses to intermittent exercise of different intensities: plasma changes in a pancreatic beta-cell peptide, amylin.
Journal: Metabolism: clinical and experimental 20020501
Title: Acute 3rd-ventricular amylin infusion potently reduces food intake but does not produce aversive consequences.
Journal: Peptides 20020501
Title: Islet amyloid: phase partitioning and secondary nucleation are central to the mechanism of fibrillogenesis.
Journal: Biochemistry 20020409
Title: A randomized study and open-label extension evaluating the long-term efficacy of pramlintide as an adjunct to insulin therapy in type 1 diabetes.
Journal: Diabetes care 20020401
Title: Functional interaction of G protein-coupled receptors of the adrenomedullin peptide family with accessory receptor-activity-modifying proteins (RAMP).
Journal: Microscopy research and technique 20020401
Title: Effects of pramlintide, an amylin analogue, on gastric emptying in type 1 and 2 diabetes mellitus.
Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20020401
Title: Effects of amylin and salmon calcitonin on feeding and drinking behavior in pygmy goats.
Journal: Physiology & behavior 20020401
Title: Novel peptides under development for the treatment of type 1 and type 2 diabetes mellitus.
Journal: Current drug targets. Immune, endocrine and metabolic disorders 20020401
Title: Amylin is associated with delayed gastric emptying in critically ill children.
Journal: Intensive care medicine 20020301
Title: Current and future perspective in the management of diabetes.
Journal: Journal of the Indian Medical Association 20020301
Title: Insulin and amylin release are both diminished in first-degree relatives of subjects with type 2 diabetes.
Journal: Diabetes care 20020201
Title: Transient increase of rat gastric amylin in the neonatal period and in experimental ulcers.
Journal: Journal of gastroenterology 20020101
Title: Role of amylin in insulin secretion and action in humans: antagonist studies across the spectrum of insulin sensitivity.
Journal: Diabetes/metabolism research and reviews 20020101
Title: Adjunctive therapy with the amylin analogue pramlintide leads to a combined improvement in glycemic and weight control in insulin-treated subjects with type 2 diabetes.
Journal: Diabetes technology & therapeutics 20020101
Title: Pramlintide: an agent for glycemic control plus weight control?
Journal: Diabetes technology & therapeutics 20020101
Title: Unresolved challenges with insulin therapy in type 1 and type 2 diabetes: potential benefit of replacing amylin, a second beta-cell hormone.
Journal: Diabetes technology & therapeutics 20020101
Title: Is pramlintide an adjunct to insulin therapy?
Journal: Diabetes technology & therapeutics 20020101
Title: Amylin and adrenomedullin: novel regulators of bone growth.
Journal: Current pharmaceutical design 20020101
Title: [Postpartum evaluation of amylin secretion in gestational diabetes mellitus].
Journal: Medycyna wieku rozwojowego 20020101
Title: The specificity of amylin for the diagnosis of pancreatic adenocarcinoma.
Journal: International journal of gastrointestinal cancer 20020101
Title: Production of cAMP by adrenomedullin in human oligodendroglial cell line KG1C: comparison with calcitonin gene-related peptide and amylin.
Journal: Brain research. Molecular brain research 20011216
Title: Vasorelaxant effect of glucagon-like peptide-(7-36)amide and amylin on the pulmonary circulation of the rat.
Journal: Regulatory peptides 20011215
Title: Amylin potently activates AP neurons possibly via formation of the excitatory second messenger cGMP.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20011201
Title: Enhanced in vitro production of amyloid-like fibrils from mutant (S20G) islet amyloid polypeptide.
Journal: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20011201
Title: Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology.
Journal: Biochimica et biophysica acta 20011129
Title: Glucose and forskolin regulate IAPP gene expression through different signal transduction pathways.
Journal: American journal of physiology. Endocrinology and metabolism 20011101
Title: Inhibition of central amylin signaling increases food intake and body adiposity in rats.
Journal: Endocrinology 20011101
Title: Histamine H1 receptors mediate the anorectic action of the pancreatic hormone amylin.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20011101
Title: Islet amyloid develops diffusely throughout the pancreas before becoming severe and replacing endocrine cells.
Journal: Diabetes 20011101
Title: High plasma amylin/islet amyloid polypeptide levels in patients with residual medullary thyroid carcinoma after total thyroidectomy.
Journal: European journal of endocrinology 20011101
Title: Adrenomedullin and related peptides: receptors and accessory proteins.
Journal: Peptides 20011101
Title: Pramlintide (Amylin).
Journal: Current opinion in investigational drugs (London, England : 2000) 20011101
Title: Amylin infusion into rat nucleus accumbens potently depresses motor activity and ingestive behavior.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20011001
Title: Effect of amylin on mast cell secretion as a possible mechanism increasing gastric mucosa resistance.
Journal: Bulletin of experimental biology and medicine 20011001
Title: Effect of amylin on the tone of rat aorta ring preparation.
Journal: Bulletin of experimental biology and medicine 20011001
Title: Analysis of the minimal amyloid-forming fragment of the islet amyloid polypeptide. An experimental support for the key role of the phenylalanine residue in amyloid formation.
Journal: The Journal of biological chemistry 20010907
Title: Amylin replacement with pramlintide as an adjunct to insulin therapy in type 1 and type 2 diabetes mellitus: a physiological approach toward improved metabolic control.
Journal: Current pharmaceutical design 20010901
Title: Analysis of responses to hAmylin, hCGRP, and hADM in isolated resistance arteries from the mesenteric vascular bed of the rat.
Journal: Peptides 20010901
Title: Islet amyloid polypeptide is not a satisfactory marker for detecting pancreatic cancer.
Journal: Gastroenterology 20010901
Title: In vivo glucose-stimulated amylin secretion is increased in nondiabetic patients with pancreatic cancer.
Journal: Metabolism: clinical and experimental 20010901
Title: Amylin receptor agonists: a novel pharmacological approach in the management of insulin-treated diabetes mellitus.
Journal: Expert opinion on investigational drugs 20010901
Title: Alteration in phosphorylation of P20 is associated with insulin resistance.
Journal: Diabetes 20010801
Title: Islet amyloid polypeptide promotes beta-cell proliferation in neonatal rat pancreatic islets.
Journal: Diabetologia 20010801
Title: CGRP receptors mediating CGRP-, adrenomedullin- and amylin-induced relaxation in porcine coronary arteries. Characterization with 'Compound 1' (WO98/11128), a non-peptide antagonist.
Journal: British journal of pharmacology 20010801
Title: Effects of calcitonin, amylin, and calcitonin gene-related peptide on osteoclast development.
Journal: Bone 20010801
Title: Cloning, characterization and central nervous system distribution of receptor activity modifying proteins in the rat.
Journal: The European journal of neuroscience 20010801
Title: Distribution of amylin-immunoreactive neurons in the monkey hypothalamus and their relationships with the histaminergic system.
Journal: Archives of histology and cytology 20010801
Title: Effect of insulin, proinsulin, and amylin on renin release from perfused rat kidney.
Journal: Metabolism: clinical and experimental 20010701
Title: The anorectic effect of a chronic peripheral infusion of amylin is abolished in area postrema/nucleus of the solitary tract (AP/NTS) lesioned rats.
Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20010701
Title: S20G mutation of the amylin gene is associated with Type II diabetes in Japanese. Study Group of Comprehensive Analysis of Genetic Factors in Diabetes Mellitus.
Journal: Diabetologia 20010701
Title: 'A' is for amylin and amyloid in type 2 diabetes mellitus.
Journal: JOP : Journal of the pancreas 20010701
Title: Effect of calcitonin gene related peptide on the adenylate cyclase activity in abalone gill membranes.
Journal: Regulatory peptides 20010615
Title: Dopamine D(2) receptors mediate amylin's acute satiety effect.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010601
Title: Direct inhibitory effect of adrenomedullin, calcitonin gene-related peptide, calcitonin, and amylin on cholecystokinin-induced contraction of guinea-pig isolated caecal circular smooth muscle cells.
Journal: Peptides 20010601
Title: Plasma amylin concentration is related to the severity of intestinal ischemic injury in rats.
Journal: Surgery 20010601
Title: Agouti signaling protein stimulates islet amyloid polypeptide (amylin) secretion in pancreatic beta-cells.
Journal: Experimental biology and medicine (Maywood, N.J.) 20010601
Title: The Tet-On system in transgenic mice: inhibition of the mouse pdx-1 gene activity by antisense RNA expression in pancreatic beta-cells.
Journal: Journal of molecular medicine (Berlin, Germany) 20010601
Title: Identification of a heparin binding domain in the N-terminal cleavage site of pro-islet amyloid polypeptide. Implications for islet amyloid formation.
Journal: The Journal of biological chemistry 20010518
Title: Islet amyloid polypeptide: identification of long-range contacts and local order on the fibrillogenesis pathway.
Journal: Journal of molecular biology 20010511
Title: Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis.
Journal: Journal of molecular biology 20010504
Title: Amylin and bone metabolism in streptozotocin-induced diabetic rats.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010501
Title: Evidence that amylin stimulates lipolysis in vivo: a possible mediator of induced insulin resistance.
Journal: American journal of physiology. Endocrinology and metabolism 20010401
Title: High glucose concentration favors the selective secretion of islet amyloid polypeptide through a constitutive secretory pathway in human pancreatic islets.
Journal: Pancreas 20010401
Title: Familial early-onset type 2 diabetes in Chinese patients: obesity and genetics have more significant roles than autoimmunity.
Journal: Diabetes care 20010401
Title: The islet amyloid polypeptide (amylin) gene S20G mutation in Chinese subjects: evidence for associations with type 2 diabetes and cholesterol levels.
Journal: Clinical endocrinology 20010401
Title: Promotion of formation of amyloid fibrils by aluminium adenosine triphosphate (AlATP).
Journal: Journal of inorganic biochemistry 20010401
Title: Characterization of CGRP(1) receptors in the guinea pig basilar artery.
Journal: European journal of pharmacology 20010302
Title: Selective amylin inhibition of the glucagon response to arginine is extrinsic to the pancreas.
Journal: American journal of physiology. Endocrinology and metabolism 20010301
Title: Comparative effects of amylin and cholecystokinin on food intake and gastric emptying in rats.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010301
Title: Does neuropeptide Y contribute to the anorectic action of amylin?
Journal: Peptides 20010301
Title: beta-cell dysfunction and failure in type 2 diabetes: potential mechanisms.
Journal: Diabetes 20010201
Title: New pharmacological development (alpha glucosidase inhibitors, amylin analogues, GLP-1, thiozolidinediones, short acting insulin analogues).
Journal: The Journal of the Association of Physicians of India 20010125
Title: Early changes in islet hormone secretion in the hamster pancreatic cancer model.
Journal: Teratogenesis, carcinogenesis, and mutagenesis 20010101
Title: Synthesis and purification of amyloidogenic peptides.
Journal: Analytical biochemistry 20010101
Title: Ultrastructural evidence that apoptosis is the mechanism by which human amylin evokes death in RINm5F pancreatic islet beta-cells.
Journal: Cell biology international 20010101
Title: Quantitation in receptor pharmacology.
Journal: Receptors & channels 20010101
Title: [Pancreatic hormone amylin and integrity of the gastric mucosa].
Journal: Vestnik Rossiiskoi akademii meditsinskikh nauk 20010101
Title: On the role of islet amyloid polypeptide in glucose intolerance and anorexia of pancreatic cancer.
Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20010101
Title: Amyloidogenicity and cytotoxicity of islet amyloid polypeptide.
Journal: Biopolymers 20010101
Title: Amylin: localization, effects on cerebral arteries and on local cerebral blood flow in the cat.
Journal: TheScientificWorldJournal 20010101
Title: Renal amylin binding in normotensive and hypertensive rats: effects of angiotensin converting enzyme inhibition with perindopril.
Journal: Journal of hypertension 19971101
Title: Effect of amylin in various experimental models of gastric ulcer.
Journal: European journal of pharmacology 19970806
Title: Glucose regulation of islet amyloid polypeptide gene expression in rat pancreatic islets.
Journal: The American journal of physiology 19970401
Title: Selective inhibition of Abeta fibril formation.
Journal: The Journal of biological chemistry 19960223
Title: Effect of dexamethasone on insulin sensitivity, islet amyloid polypeptide and insulin secretion in humans.
Journal: Diabetologia 19930101
Title: Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19900701
