Home Fluorides 154563-54-9
154563-54-9,MFCD00953421
Catalog No.:AA01ENJH

154563-54-9 | N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxamide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥99%(HPLC)
in stock  
$304.00   $213.00
- +
10mg
≥99%(HPLC)
in stock  
$445.00   $312.00
- +
25mg
≥99%(HPLC)
in stock  
$1,100.00   $770.00
- +
50mg
≥99%(HPLC)
in stock  
$1,682.00   $1,178.00
- +
100mg
≥99%(HPLC)
in stock  
$2,709.00   $1,897.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01ENJH
Chemical Name:
N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxamide
CAS Number:
154563-54-9
Molecular Formula:
C14H5ClF9N3O
Molecular Weight:
437.6476
MDL Number:
MFCD00953421
SMILES:
Clc1ncc(c(n1)C(F)(F)F)C(=O)Nc1cc(cc(c1)C(F)(F)F)C(F)(F)F
Properties
Computed Properties
 
Complexity:
544  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
4.7  

Literature

Title: Screening for inhibitors of transcription factors using luciferase reporter gene expression in transfected cells.

Journal: Methods in molecular biology (Clifton, N.J.) 20030101

Title: Sullivan RW, et al. 2-Chloro-4-(trifluoromethyl)pyrimidine-5-N-(3',5'- bis(trifluoromethyl)phenyl)-carboxamide: a potent inhibitor of NF-kappa B- and AP-1-mediated gene expression identified using solution-phase combinatorial chemistry. J Med Chem. 1998;41(4):413-419.

Title: Gerlag DM, et al. The effect of a T cell-specific NF-kappa B inhibitor on in vitro cytokine production and collagen-induced arthritis. J Immunol. 2000;165(3):1652-1658.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 154563-54-9
Tags:154563-54-9 Molecular Formula|154563-54-9 MDL|154563-54-9 SMILES|154563-54-9 N-[3,5-Bis(trifluoromethyl)phenyl]-2-chloro-4-(trifluoromethyl)-5-pyrimidinecarboxamide