Title: Hepatotoxicity of piperazine designer drugs: up-regulation of key enzymes of cholesterol and lipid biosynthesis.
Journal: Archives of toxicology 20161201
Title: Structure-dependent inhibition of the human α1β2γ2 GABAA receptor by piperazine derivatives: A novel mode of action.
Journal: Neurotoxicology 20151201
Title: Estrogenic effects and their action mechanism of the major active components of party pill drugs.
Journal: Toxicology letters 20121115
Title: Piperazine compounds as drugs of abuse.
Journal: Drug and alcohol dependence 20120501
Title: 1-(4,5,6,7-Tetra-hydro-thieno[3,2-c]pyridin-5-yl)-2-{4-[3-(trifluoro-meth-yl)phen-yl]piperazin-1-yl}ethanone.
Journal: Acta crystallographica. Section E, Structure reports online 20120501
Title: Determination of piperazine-type stimulants in human urine by means of microextraction in packed sorbent and high performance liquid chromatography-diode array detection.
Journal: Journal of pharmaceutical and biomedical analysis 20120305
Title: Rapid determination of piperazine-type stimulants in human urine by microextraction in packed sorbent after method optimization using a multivariate approach.
Journal: Journal of chromatography. A 20120127
Title: Microcrystalline identification of selected designer drugs.
Journal: Forensic science international 20120110
Title: Simultaneous determination of N-benzylpiperazine and 1-(3-trifluoromethylphenyl)piperazine in rat plasma by HPLC-fluorescence detection and its application to monitoring of these drugs.
Journal: Biomedical chromatography : BMC 20120101
Title: Acute oral toxicity evaluations of some zinc(II) complexes derived from 1-(2-salicylaldiminoethyl)piperazine Schiff bases in rats.
Journal: International journal of molecular sciences 20120101
Title: Structural insights from binding poses of CCR2 and CCR5 with clinically important antagonists: a combined in silico study.
Journal: PloS one 20120101
Title: Subjective effects in humans following administration of party pill drugs BZP and TFMPP alone and in combination.
Journal: Drug testing and analysis 20110901
Title: An analysis of legal highs: do they contain what it says on the tin?
Journal: Drug testing and analysis 20110901
Title: Determining the subjective and physiological effects of BZP combined with TFMPP in human males.
Journal: Psychopharmacology 20110401
Title: HPLC determination of methylphenidate and its metabolite, ritalinic acid, by high-performance liquid chromatography with peroxyoxalate chemiluminescence detection.
Journal: Analytical and bioanalytical chemistry 20110401
Title: Mephedrone (4-methylmethcathinone)-related deaths.
Journal: Journal of analytical toxicology 20110401
Title: The clinical toxicology of the designer 'party pills' benzylpiperazine and trifluoromethylphenylpiperazine.
Journal: Clinical toxicology (Philadelphia, Pa.) 20110301
Title: Effects of trifluoromethylphenylpiperazine (TFMPP) on interhemispheric communication.
Journal: Psychopharmacology 20110201
Title: Development of a rapid LC-MS/MS method for direct urinalysis of designer drugs.
Journal: Drug testing and analysis 20110101
Title: Current awareness of piperazines: pharmacology and toxicology.
Journal: Drug testing and analysis 20110101
Title: Trazodone, meta-chlorophenylpiperazine (an hallucinogenic drug and trazodone metabolite), and the hallucinogen trifluoromethylphenylpiperazine cross-react with the EMIT®II ecstasy immunoassay in urine.
Journal: Journal of analytical toxicology 20101101
Title: Detection of 1-benzylpiperazine, 1-(3-trifluoromethylphenyl)-piperazine, and 1-(3-chlorophenyl)-piperazine in 3,4-methylenedioxymethamphetamine-positive urine samples.
Journal: Journal of analytical toxicology 20101001
Title: Randomised double-blind, placebo-controlled trial of the effects of the 'party pills' BZP/TFMPP alone and in combination with alcohol.
Journal: Journal of psychopharmacology (Oxford, England) 20100901
Title: Validation of an LC-MS method for the detection and quantification of BZP and TFMPP and their hydroxylated metabolites in human plasma and its application to the pharmacokinetic study of TFMPP in humans.
Journal: Journal of forensic sciences 20100901
Title: Determining the subjective effects of TFMPP in human males.
Journal: Psychopharmacology 20100801
Title: 3-Chloro-6-{4-[3-(trifluoro-meth-yl)phen-yl]piperazin-1-yl}pyridazine.
Journal: Acta crystallographica. Section E, Structure reports online 20100301
Title: Piperazines: a new class of drug of abuse has landed in Hong Kong.
Journal: Hong Kong medical journal = Xianggang yi xue za zhi 20100201
Title: Differences in harm from legal BZP/TFMPP party pills between North Island and South Island users in New Zealand: a case of effective industry self-regulation?
Journal: The International journal on drug policy 20100101
Title: Legal highs toxicity--symptomatology and clinical diagnosis in case series.
Journal: Przeglad lekarski 20100101
Title: 'Party pill' drugs--BZP and TFMPP.
Journal: The New Zealand medical journal 20091211
Title: In vivo interactions between BZP and TFMPP (party pill drugs).
Journal: The New Zealand medical journal 20090925
Title: Differentiation of the regioisomeric 2-, 3-, and 4-trifluoromethylphenylpiperazines (TFMPP) by GC-IRD and GC-MS.
Journal: Forensic science international 20090701
Title: Metabolic interactions with piperazine-based 'party pill' drugs.
Journal: The Journal of pharmacy and pharmacology 20090701
Title: Activation of serotonin 5-HT1-receptors decreased gripping-induced immobility episodes in taiep rats.
Journal: Neuroscience letters 20090109
Title: Dissociative and sympathomimetic toxicity associated with recreational use of 1-(3-trifluoromethylphenyl) piperazine (TFMPP) and 1-benzylpiperzine (BZP).
Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20081201
Title: Patterns of benzylpiperazine/trifluoromethylphenylpiperazine party pill use and adverse effects in a population sample in New Zealand.
Journal: Drug and alcohol review 20081101
Title: Serotonin transduction cascades mediate variable changes in pyloric network cycle frequency in response to the same modulatory challenge.
Journal: Journal of neurophysiology 20080601
Title: Food restriction alters N'-propyl-4,5,6,7-tetrahydrobenzothiazole-2,6-diamine dihydrochloride (pramipexole)-induced yawning, hypothermia, and locomotor activity in rats: evidence for sensitization of dopamine D2 receptor-mediated effects.
Journal: The Journal of pharmacology and experimental therapeutics 20080501
Title: Investigation of the first deaths in the United Kingdom involving the detection and quantitation of the piperazines BZP and 3-TFMPP.
Journal: Journal of analytical toxicology 20080301
Title: [1-benzylpiperazine (BZP) and 1-(3-trifluorométhylphényl)pipérazine (TFMPP): emergence of two agents which lead to misuse].
Journal: Annales pharmaceutiques francaises 20080301
Title: Detection of 1-benzylpiperazine and 1-(3-trifluoromethylphenyl)-piperazine in urine analysis specimens using GC-MS and LC-ESI-MS.
Journal: Journal of analytical toxicology 20080101
Title: The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines.
Journal: Bioorganic & medicinal chemistry 20071115
Title: Benzylpiperazine: a drug of abuse?
Journal: Journal of psychopharmacology (Oxford, England) 20071101
Title: MDMA-like behavioral effects of N-substituted piperazines in the mouse.
Journal: Pharmacology, biochemistry, and behavior 20071101
Title: Interaction of amphetamines and related compounds at the vesicular monoamine transporter.
Journal: The Journal of pharmacology and experimental therapeutics 20061001
Title: Effects of (Z)-3-hexenol, a major component of green odor, on anxiety-related behavior of the mouse in an elevated plus-maze test and biogenic amines and their metabolites in the brain.
Journal: Behavioural brain research 20060130
Title: Dopamine agonist-induced yawning in rats: a dopamine D3 receptor-mediated behavior.
Journal: The Journal of pharmacology and experimental therapeutics 20050701
Title: Metabolism of designer drugs of abuse.
Journal: Current drug metabolism 20050601
Title: Development of simultaneous gas chromatography-mass spectrometric and liquid chromatography-electrospray ionization mass spectrometric determination method for the new designer drugs, N-benzylpiperazine (BZP), 1-(3-trifluoromethylphenyl)piperazine (TFMPP) and their main metabolites in urine.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050525
Title: Differential effects of 5-HT2C receptor ligands on place conditioning and locomotor activity in rats.
Journal: European journal of pharmacology 20050516
Title: N-substituted piperazines abused by humans mimic the molecular mechanism of 3,4-methylenedioxymethamphetamine (MDMA, or 'Ecstasy').
Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050301
Title: Simultaneous separation of different types of amphetamine and piperazine designer drugs by capillary electrophoresis with a chiral selector.
Journal: Journal of forensic sciences 20050301
Title: Reinforcing and discriminative stimulus effects of 1-benzylpiperazine and trifluoromethylphenylpiperazine in rhesus monkeys.
Journal: Drug and alcohol dependence 20050214
Title: Isolation, identification and excretion profile of the principal urinary metabolite of the recently banned designer drug 1-(3-trifluoromethylphenyl)piperazine (TFMPP) in rats.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20050101
Title: Discriminative stimulus effects of ethanol in rats using a three-choice ethanol-midazolam-water discrimination.
Journal: Behavioural pharmacology 20041201
Title: Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040801
Title: Antiallodynic effects of intrathecally administered 5-HT(2C) receptor agonists in rats with nerve injury.
Journal: Pain 20040301
Title: Anxiogenic effects in the rat elevated plus-maze of 5-HT(2C) agonists into ventral but not dorsal hippocampus.
Journal: Behavioural pharmacology 20040201
Title: Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor.
Journal: European journal of pharmacology 20040126
Title: Cytochrome P450 dependent metabolism of the new designer drug 1-(3-trifluoromethylphenyl)piperazine (TFMPP). In vivo studies in Wistar and Dark Agouti rats as well as in vitro studies in human liver microsomes.
Journal: Biochemical pharmacology 20040115
Title: Common drugs of abuse--Part II.
Journal: The Journal of practical nursing 20040101
Title: New designer drug 1-(3-trifluoromethylphenyl) piperazine (TFMPP): gas chromatography/mass spectrometry and liquid chromatography/mass spectrometry studies on its phase I and II metabolism and on its toxicological detection in rat urine.
Journal: Journal of mass spectrometry : JMS 20030901
Title: Behavioural evidence of agonist-like effect of isoteoline at 5-HT1B serotonergic receptors in mice.
Journal: The Journal of pharmacy and pharmacology 20030101
Title: Involvement of 5-HT(2A/2B/2C) receptors on memory formation: simple agonism, antagonism, or inverse agonism?
Journal: Cellular and molecular neurobiology 20021201
Title: Effects of fluoxetine and TFMPP on spontaneous seizures in rats with pilocarpine-induced epilepsy.
Journal: Epilepsia 20021101
Title: Role of serotonin, gamma-aminobutyric acid, and glutamate in the behavioral thermoregulation of female tilapia during the prespawning phase.
Journal: The Journal of experimental zoology 20021001
Title: Metachlorophenylpiperazine (m-CPP) induced intracavernous pressure responses in anaesthetized rats.
Journal: International journal of impotence research 20020801
Title: Participation of 5-HT(1B) receptors in the inhibitory actions of serotonin on masculine sexual behaviour of mice: pharmacological analysis in 5-HT(1B) receptor knockout mice.
Journal: British journal of pharmacology 20020801
Title: Full substitution of the discriminative cue of a 5-HT(1A/1B/2C) agonist with the combined administration of a 5-HT(1B/2C) and a 5-HT(1A) agonist.
Journal: Behavioural pharmacology 20020701
Title: The atypical 5-HT2 receptor mediating tachycardia in pithed rats: pharmacological correlation with the 5-HT2A receptor subtype.
Journal: British journal of pharmacology 20020301
Title: Effects of serotine receptors agonists, TFMPP and CGS12066B, on regional serotonin synthesis in the rat brain: an autoradiographic study.
Journal: Journal of neurochemistry 20020301
Title: Structure-affinity relationships of a unique nicotinic ligand: N(1)-dimethyl-N(4)-phenylpiperazinium iodide (DMPP).
Journal: Journal of medicinal chemistry 20011108
Title: Piperazine-like compounds: a new group of designer drugs-of-abuse on the European market.
Journal: Forensic science international 20010915
Title: RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity.
Journal: British journal of pharmacology 20010901
Title: Discriminative stimulus properties of indorenate, a 5-HT1A, 5-HT1B and 5-HT2C agonist: a study in rats.
Journal: Journal of psychopharmacology (Oxford, England) 20010301
Title: Serotonergic modulation of retinal input to the mouse suprachiasmatic nucleus mediated by 5-HT1B and 5-HT7 receptors.
Journal: Journal of biological rhythms 20010201
Title: Modulation of 5-HT(2A) receptor-mediated head-twitch behaviour in the rat by 5-HT(2C) receptor agonists.
Journal: Pharmacology, biochemistry, and behavior 20010101
Title: The role of serotonin(2) receptors in mediating cocaine-induced convulsions.
Journal: Pharmacology, biochemistry, and behavior 20000401
Title: Agonist high and low affinity state ratios predict drug intrinsic activity and a revised ternary complex mechanism at serotonin 5-HT(2A) and 5-HT(2C) receptors.
Journal: Synapse (New York, N.Y.) 20000201
Title: The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons.
Journal: European journal of pharmacology 19970501
Title: Two amino acid differences in the sixth transmembrane domain are partially responsible for the pharmacological differences between the 5-HT1D beta and 5-HT1E 5-hydroxytryptamine receptors.
Journal: Journal of neurochemistry 19961101
Title: Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
Journal: Journal of neurochemistry 19960101
Title: Penile erection and yawning induced by 5-HT1C receptor agonists in male rats: relationship with dopaminergic and oxytocinergic transmission.
Journal: European journal of pharmacology 19940811
Title: Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
Journal: The Journal of biological chemistry 19930825
Title: Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
Journal: Molecular pharmacology 19930801
Title: Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
Journal: Molecular pharmacology 19930301
Title: Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization.
Journal: Molecular pharmacology 19930301
Title: Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Journal: Molecular pharmacology 19930301
Title: Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19930115
Title: Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1D alpha and 5-HT1D beta.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19920415
Title: Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor.
Journal: Molecular pharmacology 19910801
Title: In-vivo metabolism in the rat and mouse of antrafenine to 1-m-trifluoromethylphenylpiperazine.
Journal: The Journal of pharmacy and pharmacology 19850101
