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158484-42-5
Catalog No.:AA00AKOB

158484-42-5 | ω-Agatoxin TK

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Technical Information
Catalog Number:
AA00AKOB
Chemical Name:
ω-Agatoxin TK
CAS Number:
158484-42-5
Molecular Formula:
C215H337N65O70S10
Molecular Weight:
5273.0198
SMILES:
NCCCCC1NC(=O)C(NC(=O)CNC(=O)CNC(=O)C(NC(=O)C(NC(=O)C2CSSCC3NC(=O)C4N(C(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CSSCC(NC(=O)C(CCC(=O)O)NC(=O)C1CSSCC(NC(=O)C(CCCNC(=N)N)NC3=O)C(=O)NC(CO)C(=O)NC(CCSC)C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N1)CC(=O)N)C(O)C)C(CC)C)C(=O)NC(C(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)O)C)Cc1ccccc1)CO)CC(C)C)CCC(=O)O)CCSC)C(CC)C)CC(C)C)CCCNC(=N)N)C(O)C)CSSCC(NC(=O)C(NC(=O)C(NC(=O)C(CCC(=O)O)N)CC(=O)O)CC(=O)N)C(=O)NC(C(CC)C)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(C(=O)NCC(=O)NC(C(=O)N2)CCCCN)Cc1ccc(cc1)O)CCCNC(=N)N)CCCNC(=N)N)CCC4)C(O)C)Cc1c[nH]c2c1cccc2)C(O)C
Properties

Literature

Title: María Sitges, et al. Omega-agatoxin-TK is a useful tool to study P-type Ca2+ channel-mediated changes in internal Ca2+ and glutamate release in depolarised brain nerve terminals. Neurochem Int. 2005 Jan;46(1):53-60.

Title: M Kimura, et al. Involvement of P-type calcium channels in high potassium-elicited release of neurotransmitters from rat brain slices. Neuroscience. 1995 Jun;66(3):609-15.

Title: M Kuwada, et al. Omega-agatoxin-TK containing D-serine at position 46, but not synthetic omega-[L-Ser46agatoxin-TK, exerts blockade of P-type calcium channels in cerebellar Purkinje neurons. Mol Pharmacol. 1994 Oct;46(4):587-93.

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