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159351-69-6,MFCD00929329
Catalog No.:AA001QJO

159351-69-6 | Everolimus

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Purity
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Quantity
  
5mg
≥95%
in stock  
$70.00   $49.00
- +
100mg
98%
in stock  
$117.00   $82.00
- +
250mg
98%
in stock  
$192.00   $135.00
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1g
95%
in stock  
$693.00   $485.00
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5g
95%
in stock  
$2,663.00   $1,864.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001QJO
Chemical Name:
Everolimus
CAS Number:
159351-69-6
Molecular Formula:
C53H83NO14
Molecular Weight:
958.2244
MDL Number:
MFCD00929329
SMILES:
OCCO[C@@H]1CC[C@H](C[C@H]1OC)C[C@H]([C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H](CC[C@H]2C)C[C@H](OC)C(=CC=CC=C[C@H](C[C@H](C(=O)[C@@H]([C@@H](C(=C[C@H](C(=O)C1)C)C)O)OC)C)C)C)C
Properties
Computed Properties
 
Complexity:
1810  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
15  
Defined Bond Stereocenter Count:
4  
Heavy Atom Count:
68  
Hydrogen Bond Acceptor Count:
14  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
9  
XLogP3:
5.9  

Literature

Title: Human breast cancer cells display different sensitivities to ABT-263 based on the level of survivin.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20180201

Title: Novel Hsp90 inhibitor platycodin D disrupts Hsp90/Cdc37 complex and enhances the anticancer effect of mTOR inhibitor.

Journal: Toxicology and applied pharmacology 20170901

Title: Everolimus suppresses invasion and migration of renal cell carcinoma by inhibiting FAK activity and reversing epithelial to mesenchymal transition in vitro and in vivo.

Journal: Environmental toxicology 20170701

Title: The bromodomain inhibitor OTX015 (MK-8628) exerts anti-tumor activity in triple-negative breast cancer models as single agent and in combination with everolimus.

Journal: Oncotarget 20170131

Title: OTX015 (MK-8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models.

Journal: International journal of cancer 20161101

Title: Bromodomain inhibitor OTX015 (MK-8628) combined with targeted agents shows strong in vivo antitumor activity in lymphoma.

Journal: Oncotarget 20160906

Title: Metal allergy to everolimus-eluting cobalt chromium stents confirmed by positive skin testing as a cause of recurrent multivessel in-stent restenosis.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20160301

Title: Everolimus pharmacokinetics and its exposure-toxicity relationship in patients with thyroid cancer.

Journal: Cancer chemotherapy and pharmacology 20160101

Title: Better Together: Targeted Combination Therapies in Breast Cancer.

Journal: Seminars in oncology 20151201

Title: Cabozantinib versus Everolimus in Advanced Renal-Cell Carcinoma.

Journal: The New England journal of medicine 20151105

Title: Enhancing Endocrine Therapy for Hormone Receptor-Positive Advanced Breast Cancer: Cotargeting Signaling Pathways.

Journal: Journal of the National Cancer Institute 20151001

Title: A comprehensively characterized large panel of head and neck cancer patient-derived xenografts identifies the mTOR inhibitor everolimus as potential new treatment option.

Journal: International journal of cancer 20150615

Title: Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers.

Journal: Oncotarget 20150201

Title: mTOR inhibition improves immune function in the elderly.

Journal: Science translational medicine 20141224

Title: An unexpected diagnosis in a renal-transplant patient with proteinuria treated with everolimus: AL amyloidosis.

Journal: Clinical nephrology 20141201

Title: A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy.

Journal: Nature chemical biology 20141201

Title: P-glycoprotein, CYP3A, and plasma carboxylesterase determine brain and blood disposition of the mTOR Inhibitor everolimus (Afinitor) in mice.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20140615

Title: A phase Ib trial of LY2584702 tosylate, a p70 S6 inhibitor, in combination with erlotinib or everolimus in patients with solid tumours.

Journal: European journal of cancer (Oxford, England : 1990) 20140301

Title: Synergistic interactions between sorafenib and everolimus in pancreatic cancer xenografts in mice.

Journal: Cancer chemotherapy and pharmacology 20130501

Title: Involvement of autophagy in the pharmacological effects of the mTOR inhibitor everolimus in acute kidney injury.

Journal: European journal of pharmacology 20121205

Title: A phase I study of temozolomide and everolimus (RAD001) in patients with newly diagnosed and progressive glioblastoma either receiving or not receiving enzyme-inducing anticonvulsants: an NCIC CTG study.

Journal: Investigational new drugs 20121201

Title: Acetylation of histone H3 prevents resistance development caused by chronic mTOR inhibition in renal cell carcinoma cells.

Journal: Cancer letters 20121101

Title: UV-visible spectroscopy as an alternative to liquid chromatography for determination of everolimus in surfactant-containing dissolution media: a useful approach based on solid-phase extraction.

Journal: Journal of pharmaceutical and biomedical analysis 20121101

Title: Proliferation signal inhibitors in the treatment of lupus nephritis: preliminary experience.

Journal: Nephrology (Carlton, Vic.) 20121101

Title: Pharmacological targeting of mammalian target of rapamycin inhibits ovarian granulosa cell tumor growth.

Journal: Carcinogenesis 20121101

Title: NVP-BEZ235 alone and in combination in mantle cell lymphoma: an effective therapeutic strategy.

Journal: Expert opinion on investigational drugs 20121101

Title: Towards excellence in revascularization for left main coronary artery disease.

Journal: Current opinion in cardiology 20121101

Title: Everolimus synergizes with gefitinib in non-small-cell lung cancer cell lines resistant to epidermal growth factor receptor tyrosine kinase inhibitors.

Journal: Cancer chemotherapy and pharmacology 20121101

Title: A drug safety evaluation of everolimus in kidney transplantation.

Journal: Expert opinion on drug safety 20121101

Title: Endothelial progenitor cell response to antiproliferative drug exposure.

Journal: Atherosclerosis 20121101

Title: Hemodialysis does not affect everolimus pharmacokinetics: two cases of patients with metastatic renal cell cancer.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20121101

Title: Clinical and histopathologic characteristics of rash in cancer patients treated with mammalian target of rapamycin inhibitors.

Journal: Cancer 20121015

Title: A comprehensive review of everolimus clinical reports: a new mammalian target of rapamycin inhibitor.

Journal: Transplantation 20121015

Title: Genome sequencing identifies a basis for everolimus sensitivity.

Journal: Science (New York, N.Y.) 20121012

Title: The XIENCE nano everolimus eluting coronary stent system for the treatment of small coronary arteries: the SPIRIT Small Vessel trial.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20121001

Title: Phase II study of everolimus in patients with locally advanced or metastatic transitional cell carcinoma of the urothelial tract: clinical activity, molecular response, and biomarkers.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20121001

Title: Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones.

Journal: Cancer letters 20121001

Title: Antitumor effect of the mTOR inhibitor everolimus in combination with trastuzumab on human breast cancer stem cells in vitro and in vivo.

Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20121001

Title: Novel agents in Hodgkin lymphoma.

Journal: Current oncology reports 20121001

Title: Combined blockade of signalling pathways shows marked anti-tumour potential in phaeochromocytoma cell lines.

Journal: Journal of molecular endocrinology 20121001

Title: Phase I study of pasireotide (SOM 230) and everolimus (RAD001) in advanced neuroendocrine tumors.

Journal: Endocrine-related cancer 20121001

Title: Effects of sotrastaurin, mycophenolic acid and everolimus on human B-lymphocyte function and activation.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20121001

Title: Everolimus for advanced pancreatic neuroendocrine tumours: a subgroup analysis evaluating Japanese patients in the RADIANT-3 trial.

Journal: Japanese journal of clinical oncology 20121001

Title: Everolimus for the treatment of pancreatic neuroendocrine tumors.

Journal: Expert opinion on pharmacotherapy 20121001

Title: FLT-PET is superior to FDG-PET for very early response prediction in NPM-ALK-positive lymphoma treated with targeted therapy.

Journal: Cancer research 20121001

Title: A phase I study of erlotinib and hydroxychloroquine in advanced non-small-cell lung cancer.

Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20121001

Title: Counteracting autophagy overcomes resistance to everolimus in mantle cell lymphoma.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20121001

Title: Everolimus in pediatric transplantation.

Journal: Current opinion in organ transplantation 20121001

Title: Analysis of cyclosporin A, tacrolimus, sirolimus, and everolimus in dried blood spot samples using liquid chromatography tandem mass spectrometry.

Journal: Analytical and bioanalytical chemistry 20121001

Title: Arsenic trioxide synergizes with everolimus (Rad001) to induce cytotoxicity of ovarian cancer cells through increased autophagy and apoptosis.

Journal: Endocrine-related cancer 20121001

Title: Everolimus and erlotinib as second- or third-line therapy in patients with advanced non-small-cell lung cancer.

Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20121001

Title: Comparison of twelve-month outcomes after percutanous coronary intervention with everolimus-eluting versus zotarolimus-eluting or sirolimus-eluting stents from the PROENCY (PROmus ENdeavor CYpher) registry.

Journal: The Journal of invasive cardiology 20121001

Title: Late stent thrombosis of a second-generation drug- eluting stent.

Journal: The Journal of invasive cardiology 20121001

Title: Vascular healing in drug-eluting stents: differential drug-associated response of limus-eluting stents in a preclinical model of stent implantation.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20121001

Title: Wound healing complications and the use of mammalian target of rapamycin inhibitors in kidney transplantation: a critical review of the literature.

Journal: Transplantation 20120927

Title: Co-administration strategy to enhance brain accumulation of vandetanib by modulating P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp1/Abcg2) mediated efflux with m-TOR inhibitors.

Journal: International journal of pharmaceutics 20120915

Title: Cost-effectiveness of everolimus- versus paclitaxel-eluting stents for patients undergoing percutaneous coronary revascularization (from the SPIRIT-IV Trial).

Journal: The American journal of cardiology 20120915

Title: Human TSC-associated renal angiomyolipoma cells are hypersensitive to ER stress.

Journal: American journal of physiology. Renal physiology 20120915

Title: K-Ras mutation-mediated IGF-1-induced feedback ERK activation contributes to the rapalog resistance in pancreatic ductal adenocarcinomas.

Journal: Cancer letters 20120901

Title: Enduring response to everolimus as third-line therapy in a patient with advanced renal cell carcinoma, including small-bowel metastases: loss of FHIT but normal VHL gene status.

Journal: Clinical genitourinary cancer 20120901

Title: Case of complete response to everolimus for metastatic renal cell carcinoma.

Journal: International journal of urology : official journal of the Japanese Urological Association 20120901

Title: Efficacy of everolimus, a novel mTOR inhibitor, against basal-like triple-negative breast cancer cells.

Journal: Cancer science 20120901

Title: Effect of immunosuppressive drugs on spontaneous DNA repair in human peripheral blood mononuclear cells.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20120901

Title: Inhibition of mTOR in carcinoid tumors.

Journal: Targeted oncology 20120901

Title: Incidence and risk of pulmonary toxicity in patients treated with mTOR inhibitors for malignancy. A meta-analysis of published trials.

Journal: Acta oncologica (Stockholm, Sweden) 20120901

Title: Resistance to targeted therapies in pancreatic neuroendocrine tumors (PNETs): molecular basis, preclinical data, and counteracting strategies.

Journal: Targeted oncology 20120901

Title: Everolimus: a new treatment option for advanced pancreatic neuroendocrine tumors.

Journal: The Annals of pharmacotherapy 20120901

Title: Conversion from calcineurin inhibitors to everolimus with low-dose cyclosporine in renal transplant recipients with squamous cell carcinoma of the skin.

Journal: Transplantation proceedings 20120901

Title: Everolimus and enteric-coated mycophenolate sodium ab initio after liver transplantation: midterm results.

Journal: Transplantation proceedings 20120901

Title: Resistance to the mTOR-inhibitor RAD001 elevates integrin α2- and β1-triggered motility, migration and invasion of prostate cancer cells.

Journal: British journal of cancer 20120821

Title: Sirolimus and everolimus intestinal absorption and interaction with calcineurin inhibitors: a differential effect between cyclosporine and tacrolimus.

Journal: Fundamental & clinical pharmacology 20120801

Title: Phase I and pharmacokinetic study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced solid malignancies.

Journal: Investigational new drugs 20120801

Title: Analysis of 1 year virtual histology changes in coronary plaque located behind the struts of the everolimus eluting bioresorbable vascular scaffold.

Journal: The international journal of cardiovascular imaging 20120801

Title: Connective tissue growth factor (CTGF/CCN2): a protagonist in cardiac allograft vasculopathy development?

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120801

Title: Randomized phase II trial of everolimus in combination with tamoxifen in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer with prior exposure to aromatase inhibitors: a GINECO study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120801

Title: Inhibition of the mTOR/S6K signal is necessary to enhance fluorouracil-induced apoptosis in gastric cancer cells with HER2 amplification.

Journal: International journal of oncology 20120801

Title: Combination of sorafenib and everolimus impacts therapeutically on adrenocortical tumor models.

Journal: Endocrine-related cancer 20120801

Title: Xience side branch access stent for treatment of bifurcation coronary disease: a review of preclinical data.

Journal: Journal of interventional cardiology 20120801

Title: Phase I study of bevacizumab, everolimus, and panobinostat (LBH-589) in advanced solid tumors.

Journal: Cancer chemotherapy and pharmacology 20120801

Title: Flow patterns at stented coronary bifurcations: computational fluid dynamics analysis.

Journal: Circulation. Cardiovascular interventions 20120801

Title: Pregnancy in a kidney transplant patient treated with everolimus.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20120801

Title: Non-clear cell renal cell carcinoma: does the mammalian target of rapamycin represent a rational therapeutic target?

Journal: The oncologist 20120801

Title: Targeting angiogenesis in metastatic breast cancer.

Journal: The oncologist 20120801

Title: The mTOR inhibitor everolimus in combination with carboplatin in metastatic breast cancer--a phase I trial.

Journal: Anticancer research 20120801

Title: In silico prediction for the investigation of comedication interferences in quantitative LC-MS detection in the SRM mode.

Journal: Bioanalysis 20120801

Title: Second-generation everolimus-eluting stents versus first-generation sirolimus-eluting stents in acute myocardial infarction. 1-year results of the randomized XAMI (XienceV Stent vs. Cypher Stent in Primary PCI for Acute Myocardial Infarction) trial.

Journal: Journal of the American College of Cardiology 20120731

Title: Everolimus is an active agent in medullary thyroid cancer: a clinical and in vitro study.

Journal: Journal of cellular and molecular medicine 20120701

Title: Preliminary report of the use of everolimus in a patient with progressive medullary thyroid carcinoma.

Journal: Clinical endocrinology 20120701

Title: Everolimus in combination with cyclosporin a as pre- and posttransplantation immunosuppressive therapy in nonmyeloablative allogeneic hematopoietic stem cell transplantation.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120701

Title: A multicenter phase II trial (SAKK 36/06) of single-agent everolimus (RAD001) in patients with relapsed or refractory mantle cell lymphoma.

Journal: Haematologica 20120701

Title: Optimisation of the tumour response threshold in patients treated with everolimus for metastatic renal cell carcinoma: analysis of response and progression-free survival in the RECORD-1 study.

Journal: European journal of cancer (Oxford, England : 1990) 20120701

Title: Effects of the combination of RAD001 and docetaxel on breast cancer stem cells.

Journal: European journal of cancer (Oxford, England : 1990) 20120701

Title: Impact of routine angiographic follow-up after percutaneous coronary intervention with drug-eluting stents in the SPIRIT III randomized trial at three years.

Journal: The American journal of cardiology 20120701

Title: Pneumonitis associated with mTOR inhibitors therapy in patients with metastatic renal cell carcinoma: incidence, radiographic findings and correlation with clinical outcome.

Journal: European journal of cancer (Oxford, England : 1990) 20120701

Title: A randomized, controlled study to assess the conversion from calcineurin-inhibitors to everolimus after liver transplantation--PROTECT.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120701

Title: Everolimus quantification in peripheral blood mononuclear cells using ultra high performance liquid chromatography tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20120701

Title: Population pharmacokinetics and pharmacogenetics of everolimus in renal transplant patients.

Journal: Clinical pharmacokinetics 20120701

Title: A phase I study of bevacizumab, everolimus and panitumumab in advanced solid tumors.

Journal: Cancer chemotherapy and pharmacology 20120701

Title: Everolimus: a challenging drug in the treatment of multifocal inoperable cardiac rhabdomyoma.

Journal: Pediatrics 20120701

Title: [Remission of an iatrogenic Kaposi sarcoma in a patient with myasthenia gravis after switching immunosuppressive therapy to the mTOR inhibitor everolimus].

Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20120701

Title: Implications of the new histological classification (WHO 2010) for pancreatic neuroendocrine neoplasms.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20120701

Title: Efficacy of sequential treatment with sunitinib-everolimus in an orthotopic mouse model of renal cell carcinoma.

Journal: Anticancer research 20120701

Title: mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma.

Journal: Science translational medicine 20120620

Title: Review of cytomegalovirus infection findings with mammalian target of rapamycin inhibitor-based immunosuppressive therapy in de novo renal transplant recipients.

Journal: Transplantation 20120615

Title: Long-term clinical and angiographic outcome after treatment of chronic total occlusion with everolimus or sirolimus eluting stents.

Journal: International journal of cardiology 20120614

Title: Short- and long-term outcomes with drug-eluting and bare-metal coronary stents: a mixed-treatment comparison analysis of 117 762 patient-years of follow-up from randomized trials.

Journal: Circulation 20120612

Title: Further developments for improving response and tolerance to irradiation for advanced renal cancer: concurrent (mTOR) inhibitor RAD001 and helical tomotherapy.

Journal: Investigational new drugs 20120601

Title: Everolimus-related organizing pneumonia: a report establishing causality.

Journal: Investigational new drugs 20120601

Title: 40-O -[2-Hydroxyethyl]rapamycin modulates human dendritic cell function during exposure to Aspergillus fumigatus.

Journal: Journal of basic microbiology 20120601

Title: Early treatment with everolimus exerts nephroprotective effect in rats with adriamycin-induced nephrotic syndrome.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120601

Title: Primary anti-vascular endothelial growth factor (VEGF)-refractory metastatic renal cell carcinoma: clinical characteristics, risk factors, and subsequent therapy.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20120601

Title: Cyclosporine lowering with everolimus versus mycophenolate mofetil in heart transplant recipients: long-term follow-up of the SHIRAKISS randomized, prospective study.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120601

Title: Post-transcriptional modulation of C/EBPα prompts monocytic differentiation and apoptosis in acute myelomonocytic leukaemia cells.

Journal: Leukemia research 20120601

Title: Everolimus-eluting versus sirolimus-eluting stents: an updated meta-analysis of randomized trials.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20120601

Title: Pancreatic neuroendocrine and carcinoid tumors: what's new, what's old, and what's different?

Journal: Current oncology reports 20120601

Title: Effect of everolimus on pre-existing atherosclerosis in LDL-receptor deficient mice.

Journal: Atherosclerosis 20120601

Title: Combination of Rad001 (everolimus) and propachlor synergistically induces apoptosis through enhanced autophagy in prostate cancer cells.

Journal: Molecular cancer therapeutics 20120601

Title: Endothelial-dependent vasomotion in a coronary segment treated by ABSORB everolimus-eluting bioresorbable vascular scaffold system is related to plaque composition at the time of bioresorption of the polymer: indirect finding of vascular reparative therapy?

Journal: European heart journal 20120601

Title: Circulating biomarkers of response to sunitinib in gastroenteropancreatic neuroendocrine tumors: current data and clinical outlook.

Journal: Molecular diagnosis & therapy 20120601

Title: A further step towards vascular reparative therapy.

Journal: European heart journal 20120601

Title: New targeted agents in gastroenteropancreatic neuroendocrine tumors.

Journal: Targeted oncology 20120601

Title: Everolimus in different combinations as maintenance immunosuppressive therapy in heart transplant recipients.

Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120601

Title: Everolimus-induced lymphedema in a renal transplant recipient: a case report.

Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120601

Title: Conversion from cyclosporine to everolimus at 4.5 months posttransplant: 3-year results from the randomized ZEUS study.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120601

Title: [Renal carcinoma: point on treatment of brain metastasis].

Journal: Bulletin du cancer 20120601

Title: Targeting mTOR in mantle cell lymphoma: current and future directions.

Journal: Best practice & research. Clinical haematology 20120601

Title: Lymphedema of the breast as a symptom of internal diseases or side effect of mTor inhibitors.

Journal: Lymphatic research and biology 20120601

Title: Contemporary incidence and predictors of stent thrombosis and other major adverse cardiac events in the year after XIENCE V implantation: results from the 8,061-patient XIENCE V United States study.

Journal: JACC. Cardiovascular interventions 20120601

Title: The BOLERO-2 trial: the addition of everolimus to exemestane in the treatment of postmenopausal hormone receptor-positive advanced breast cancer.

Journal: Future oncology (London, England) 20120601

Title: Medium to long-term clinical outcomes with everolimus-eluting stents in real-life percutaneous coronary intervention.

Journal: Annals of the Academy of Medicine, Singapore 20120601

Title: Impact of age on clinical outcomes after everolimus-eluting and paclitaxel-eluting stent implantation: pooled analysis from the SPIRIT III and SPIRIT IV clinical trials.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120515

Title: Inhibition of influenza A virus replication by antagonism of a PI3K-AKT-mTOR pathway member identified by gene-trap insertional mutagenesis.

Journal: Antiviral chemistry & chemotherapy 20120514

Title: Agreement and reproducibility of gray-scale intravascular ultrasound and optical coherence tomography for the analysis of the bioresorbable vascular scaffold.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501

Title: A phase 1 study of weekly everolimus (RAD001) in combination with docetaxel in patients with metastatic breast cancer.

Journal: Cancer 20120501

Title: Everolimus exhibits efficacy as a radiosensitizer in a model of non-small cell lung cancer.

Journal: Oncology reports 20120501

Title: Donor-specific HLA antibodies in a cohort comparing everolimus with cyclosporine after kidney transplantation.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120501

Title: Safety and efficacy of the XIENCE V everolimus-eluting stent compared to first-generation drug-eluting stents in contemporary clinical practice.

Journal: The American journal of cardiology 20120501

Title: Everolimus triggers cytokine release by macrophages: rationale for stents eluting everolimus and a glucocorticoid.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20120501

Title: Patterns of interstitial lung disease during everolimus treatment in patients with metastatic renal cell carcinoma.

Journal: Japanese journal of clinical oncology 20120501

Title: Limus is not limus--a proposal to adjust terminology in the context of drug-eluting stents.

Journal: Journal of cardiovascular pharmacology 20120501

Title: Cyclosporin but not everolimus inhibits chemokine receptor expression on CD4+ T cell subsets circulating in the peripheral blood of renal transplant recipients.

Journal: Clinical and experimental immunology 20120501

Title: Everolimus plus early tacrolimus minimization: a phase III, randomized, open-label, multicentre trial in renal transplantation.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20120501

Title: Objective versus subjective guidance of (bioabsorbable) stent implantation: the saga continues.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501

Title: Proximal and distal maximal luminal diameters as a guide to appropriate deployment of the ABSORB everolimus-eluting bioresorbable vascular scaffold: a sub-study of the ABSORB Cohort B and the on-going ABSORB EXTEND Single Arm Study.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501

Title: Cardiac allograft vasculopathy compared by intravascular ultrasound sonography: everolimus to mycophenolate mofetil--one single-center experience.

Journal: Transplantation proceedings 20120501

Title: Clinical experience of tacrolimus with everolimus in heart transplantation.

Journal: Transplantation proceedings 20120501

Title: Metformin and the mTOR inhibitor everolimus (RAD001) sensitize breast cancer cells to the cytotoxic effect of chemotherapeutic drugs in vitro.

Journal: Anticancer research 20120501

Title: The SPIRIT V diabetic study: a randomized clinical evaluation of the XIENCE V everolimus-eluting stent vs the TAXUS Liberté paclitaxel-eluting stent in diabetic patients with de novo coronary artery lesions.

Journal: American heart journal 20120501

Title: Late subcapsular lymphocele in a kidney graft.

Journal: Transplantation 20120427

Title: The pan-deacetylase inhibitor panobinostat induces cell death and synergizes with everolimus in Hodgkin lymphoma cell lines.

Journal: Blood 20120426

Title: Short- versus long-term duration of dual-antiplatelet therapy after coronary stenting: a randomized multicenter trial.

Journal: Circulation 20120424

Title: Everolimus in metastatic renal cell carcinoma patients intolerant to previous VEGFr-TKI therapy: a RECORD-1 subgroup analysis.

Journal: British journal of cancer 20120424

Title: The struggle for energy in podocytes leads to nephrotic syndrome.

Journal: Cell cycle (Georgetown, Tex.) 20120415

Title: Primary endpoint results of the EVOLVE trial: a randomized evaluation of a novel bioabsorbable polymer-coated, everolimus-eluting coronary stent.

Journal: Journal of the American College of Cardiology 20120410

Title: A randomized controlled trial in second-generation zotarolimus-eluting Resolute stents versus everolimus-eluting Xience V stents in real-world patients: the TWENTE trial.

Journal: Journal of the American College of Cardiology 20120410

Title: Major determinants for the uncovered stent struts on optical coherence tomography after drug-eluting stent implantation.

Journal: The international journal of cardiovascular imaging 20120401

Title: Optical coherence tomography findings of very late stent thrombosis after drug-eluting stent implantation.

Journal: The international journal of cardiovascular imaging 20120401

Title: Combination of targeted agents in metastatic renal cell carcinoma: a path forward or a dead-end street?

Journal: Cancer 20120401

Title: Phase 1 trial of everolimus plus sunitinib in patients with metastatic renal cell carcinoma.

Journal: Cancer 20120401

Title: Dynamic contrast-enhanced micro-CT on mice with mammary carcinoma for the assessment of antiangiogenic therapy response.

Journal: European radiology 20120401

Title: Pharmacologic inhibition of mTOR antagonizes the cytotoxic activity of pemetrexed in non-small cell lung cancer.

Journal: Journal of cancer research and clinical oncology 20120401

Title: Determination of everolimus in blood samples from kidney and liver transplant recipients using the sirolimus chemiluminescence magnetic microparticle immunoassay (CMIA) on the Architect-i1000® system.

Journal: Scandinavian journal of clinical and laboratory investigation 20120401

Title: Everolimus-eluting stents and paclitaxel-eluting stents in patients presenting with myocardial infarction: insights from the two-year results of the COMPARE prospective randomised controlled trial.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401

Title: Efficacy and safety of everolimus in elderly patients with metastatic renal cell carcinoma: an exploratory analysis of the outcomes of elderly patients in the RECORD-1 Trial.

Journal: European urology 20120401

Title: Immunological advantages of everolimus versus cyclosporin A in liver-transplanted recipients, as revealed by polychromatic flow cytometry.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20120401

Title: Analytical performance of a new liquid chromatography/tandem mass spectrometric method for determination of everolimus concentrations in whole blood.

Journal: Therapeutic drug monitoring 20120401

Title: New strategies for advanced neuroendocrine tumors in the era of targeted therapy.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120401

Title: Everolimus: preventing organ rejection in adult kidney transplant recipients.

Journal: Expert opinion on pharmacotherapy 20120401

Title: Periprocedural myocardial infarction in a randomized trial of everolimus-eluting and Paclitaxel-eluting coronary stents: frequency and impact on mortality according to historic versus universal definitions.

Journal: Circulation. Cardiovascular interventions 20120401

Title: Everolimus: targeted therapy on the horizon for the treatment of breast cancer.

Journal: Pharmacotherapy 20120401

Title: Successful sealing of a coronary artery perforation with a mesh-covered stent.

Journal: The Journal of invasive cardiology 20120401

Title: Breakthroughs in myeloproliferative neoplasms.

Journal: Hematology (Amsterdam, Netherlands) 20120401

Title: The prequel: defining prognostically important criteria in the periprocedural PCI troponin saga.

Journal: Circulation. Cardiovascular interventions 20120401

Title: Differences in neointimal thickness between the adluminal and the abluminal sides of malapposed and side-branch struts in a polylactide bioresorbable scaffold: evidence in vivo about the abluminal healing process.

Journal: JACC. Cardiovascular interventions 20120401

Title: DUrable polymer-based sTent CHallenge of Promus ElemEnt versus ReSolute integrity (DUTCH PEERS): rationale and study design of a randomized multicenter trial in a Dutch all-comers population.

Journal: American heart journal 20120401

Title: ComparisOn of neointimal coVerage betwEen zotaRolimus-eluting stent and everolimus-eluting stent using Optical Coherence Tomography (COVER OCT).

Journal: American heart journal 20120401

Title: Phase II study of concurrent radiation therapy, temozolomide, and bevacizumab followed by bevacizumab/everolimus as first-line treatment for patients with glioblastoma.

Journal: Clinical advances in hematology & oncology : H&O 20120401

Title: Randomized trial of optimal treatment strategies for in-stent restenosis after drug-eluting stent implantation.

Journal: Journal of the American College of Cardiology 20120320

Title: Effect of everolimus on left ventricular hypertrophy of de novo kidney transplant recipients: a 1 year, randomized, controlled trial.

Journal: Transplantation 20120315

Title: PIK3CA/PTEN mutations and Akt activation as markers of sensitivity to allosteric mTOR inhibitors.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120315

Title: Randomized comparison of everolimus-eluting and sirolimus-eluting stents in patients treated with percutaneous coronary intervention: the Scandinavian Organization for Randomized Trials with Clinical Outcome IV (SORT OUT IV).

Journal: Circulation 20120313

Title: Phase II study of everolimus with biomarker exploration in patients with advanced gastric cancer refractory to chemotherapy including fluoropyrimidine and platinum.

Journal: British journal of cancer 20120313

Title: Intratumor heterogeneity and branched evolution revealed by multiregion sequencing.

Journal: The New England journal of medicine 20120308

Title: Very late coronary stent thrombosis of a newer-generation everolimus-eluting stent compared with early-generation drug-eluting stents: a prospective cohort study.

Journal: Circulation 20120306

Title: Synergistic anti-tumor effects of RAD001 with MEK inhibitors in neuroendocrine tumors: a potential mechanism of therapeutic limitation of mTOR inhibitor.

Journal: Molecular and cellular endocrinology 20120305

Title: Quantitative multi-modality imaging analysis of a fully bioresorbable stent: a head-to-head comparison between QCA, IVUS and OCT.

Journal: The international journal of cardiovascular imaging 20120301

Title: Favorable neointimal coverage in everolimus-eluting stent at 9 months after stent implantation: comparison with sirolimus-eluting stent using optical coherence tomography.

Journal: The international journal of cardiovascular imaging 20120301

Title: Evaluation with in vivo optical coherence tomography and histology of the vascular effects of the everolimus-eluting bioresorbable vascular scaffold at two years following implantation in a healthy porcine coronary artery model: implications of pilot results for future pre-clinical studies.

Journal: The international journal of cardiovascular imaging 20120301

Title: Perioperative rupture of the LIMA graft leading to cardiogenic shock, emergency angiography, and stenting with a polytetrafluoroethylene-covered stent.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301

Title: Effects of everolimus in combination with sildenafil in monocrotaline-induced pulmonary hypertension in rats.

Journal: Cardiovascular toxicology 20120301

Title: New targeted therapies in pituitary carcinoma resistant to temozolomide.

Journal: Pituitary 20120301

Title: A phase I study of daily everolimus plus low-dose weekly cisplatin for patients with advanced solid tumors.

Journal: Cancer chemotherapy and pharmacology 20120301

Title: Withdrawal of proliferation signal inhibitors due to adverse events in the maintenance phase of heart transplantation.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120301

Title: Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma.

Journal: Neuro-oncology 20120301

Title: Phase I trial of everolimus plus sorafenib for patients with advanced renal cell cancer.

Journal: Clinical genitourinary cancer 20120301

Title: Clinical review: Current scientific rationale for the use of somatostatin analogs and mTOR inhibitors in neuroendocrine tumor therapy.

Journal: The Journal of clinical endocrinology and metabolism 20120301

Title: Circumferential evaluation of the neointima by optical coherence tomography after ABSORB bioresorbable vascular scaffold implantation: can the scaffold cap the plaque?

Journal: Atherosclerosis 20120301

Title: The effects of immunosuppressants on vascular function, systemic oxidative stress and inflammation in rats.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20120301

Title: Polycystic kidney disease: a 2011 update.

Journal: Current opinion in nephrology and hypertension 20120301

Title: mTOR inhibitors and its role in the treatment of head and neck squamous cell carcinoma.

Journal: Current treatment options in oncology 20120301

Title: Fatal acute pulmonary injury associated with everolimus.

Journal: The Annals of pharmacotherapy 20120301

Title: Improvement in renal function after everolimus introduction and calcineurin inhibitor reduction in maintenance thoracic transplant recipients: the significance of baseline glomerular filtration rate.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120301

Title: Current status of immunosuppressive agents for solid organ transplantation in children.

Journal: Pediatric transplantation 20120301

Title: Advances in the treatment of relapsed or refractory Hodgkin's lymphoma.

Journal: The oncologist 20120301

Title: Everolimus as primary immunosuppression in kidney transplantation: experience in conversion from calcineurin inhibitors.

Journal: Transplantation 20120227

Title: Drug interaction between cyclosporine and mTOR inhibitors in experimental model of chronic cyclosporine nephrotoxicity and pancreatic islet dysfunction.

Journal: Transplantation 20120227

Title: Aberrant activation of the mTOR pathway and anti-tumour effect of everolimus on oesophageal squamous cell carcinoma.

Journal: British journal of cancer 20120227

Title: Everolimus alters white matter diffusion in tuberous sclerosis complex.

Journal: Neurology 20120221

Title: New therapies for tuber-less sclerosis: white matter matters?

Journal: Neurology 20120221

Title: Akt and p53 are potential mediators of reduced mammary tumor growth by cloroquine and the mTOR inhibitor RAD001.

Journal: Biochemical pharmacology 20120215

Title: Breast Cancer: Blocking both driver and escape pathways improves outcomes.

Journal: Nature reviews. Clinical oncology 20120214

Title: Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer.

Journal: The New England journal of medicine 20120209

Title: Schedule-dependent inhibition of T-cell lymphoma cells by cotreatment with the mTOR inhibitor everolimus and anticancer drugs.

Journal: Investigational new drugs 20120201

Title: Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging.

Journal: Pediatric blood & cancer 20120201

Title: [PI3K-AKT-mTOR pathway and cancer].

Journal: Bulletin du cancer 20120201

Title: An international expanded-access programme of everolimus: addressing safety and efficacy in patients with metastatic renal cell carcinoma who progress after initial vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy.

Journal: European journal of cancer (Oxford, England : 1990) 20120201

Title: [Intermittent fever under iatrogenic immunosuppression].

Journal: Der Internist 20120201

Title: Mammalian target of rapamycin (mTOR) inhibitors slow skin carcinogenesis, but impair wound healing.

Journal: The British journal of dermatology 20120201

Title: mTOR as a therapeutic target in patients with gastric cancer.

Journal: International journal of cancer 20120201

Title: Antirestenotic mechanisms of everolimus on human coronary artery smooth muscle cells: inhibition of human coronary artery smooth muscle cell proliferation, but not migration.

Journal: Journal of cardiovascular pharmacology 20120201

Title: Pharmacokinetic analysis after implantation of everolimus-eluting self-expanding stents in the peripheral vasculature.

Journal: Journal of vascular surgery 20120201

Title: Clinical outcomes in kidney transplant recipients receiving long-term therapy with inhibitors of the mammalian target of rapamycin.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120201

Title: Vascular disruption in combination with mTOR inhibition in renal cell carcinoma.

Journal: Molecular cancer therapeutics 20120201

Title: Sorafenib and Mek inhibition is synergistic in medullary thyroid carcinoma in vitro.

Journal: Endocrine-related cancer 20120201

Title: Tuberous sclerosis complex-associated angiomyolipomas: focus on mTOR inhibition.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20120201

Title: Everolimus: in patients with subependymal giant cell astrocytoma associated with tuberous sclerosis complex.

Journal: Paediatric drugs 20120201

Title: Major response to everolimus in melanoma with acquired imatinib resistance.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120201

Title: Randomized comparison of everolimus-eluting versus bare-metal stents in patients with critical limb ischemia and infrapopliteal arterial occlusive disease.

Journal: Journal of vascular surgery 20120201

Title: Everolimus in metastatic renal cell carcinoma: Subgroup analysis of patients with 1 or 2 previous vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapies enrolled in the phase III RECORD-1 study.

Journal: European journal of cancer (Oxford, England : 1990) 20120201

Title: Increasingly aggressive endovascular management of tibial artery occlusive disease.

Journal: Journal of vascular surgery 20120201

Title: Calcified in-stent restenosis: a rare cause of dilation failure requiring rotational atherectomy.

Journal: Circulation. Cardiovascular interventions 20120201

Title: Automated image analysis of nuclear shape: what can we learn from a prematurely aged cell?

Journal: Aging 20120201

Title: Long-term comparison of everolimus- and sirolimus-eluting stents in patients with acute coronary syndromes.

Journal: JACC. Cardiovascular interventions 20120201

Title: Targeted therapies for renal cell carcinoma: review of adverse event management strategies.

Journal: Journal of the National Cancer Institute 20120118

Title: Hyperpolarized 13C MR spectroscopic imaging can be used to monitor Everolimus treatment in vivo in an orthotopic rodent model of glioblastoma.

Journal: NeuroImage 20120102

Title: mTOR pathway inhibition in renal cell carcinoma.

Journal: Urologic oncology 20120101

Title: An update on targeted therapy in metastatic renal cell carcinoma.

Journal: Urologic oncology 20120101

Title: Morphological and functional evaluation of the bioresorption of the bioresorbable everolimus-eluting vascular scaffold using IVUS, echogenicity and vasomotion testing at two year follow-up: a patient level insight into the ABSORB A clinical trial.

Journal: The international journal of cardiovascular imaging 20120101

Title: Reproducibility of Shin's method for necrotic core and calcium content in atherosclerotic coronary lesions treated with bioresorbable everolimus-eluting vascular scaffolds using volumetric intravascular ultrasound radiofrequency-based analysis.

Journal: The international journal of cardiovascular imaging 20120101

Title: Efficacy and safety of sorafenib in combination with mammalian target of rapamycin inhibitors for recurrent hepatocellular carcinoma after liver transplantation.

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120101

Title: Everolimus-eluting stents for treatment of chronic total coronary occlusions.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20120101

Title: Four-year clinical follow-up of the ABSORB everolimus-eluting bioresorbable vascular scaffold in patients with de novo coronary artery disease: the ABSORB trial.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101

Title: Pharmacokinetic drug interaction between AEE788 and RAD001 causing thrombocytopenia in patients with glioblastoma.

Journal: Cancer chemotherapy and pharmacology 20120101

Title: A theoretical model to characterize the drug release behavior of drug-eluting stents with durable polymer matrix coating.

Journal: Journal of biomedical materials research. Part A 20120101

Title: Effective everolimus treatment of inoperable, life-threatening subependymal giant cell astrocytoma and intractable epilepsy in a patient with tuberous sclerosis complex.

Journal: European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20120101

Title: Spatial distribution and temporal evolution of scattering centers by optical coherence tomography in the poly(L-lactide) backbone of a bioresorbable vascular scaffold.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101

Title: Sirolimus-eluting stent vs. everolimus-eluting stent for coronary intervention in patients on chronic hemodialysis.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101

Title: mTOR inhibitor-associated proteinuria in kidney transplant recipients.

Journal: Transplantation reviews (Orlando, Fla.) 20120101

Title: Functional characterization of glycine N-methyltransferase and its interactive protein DEPDC6/DEPTOR in hepatocellular carcinoma.

Journal: Molecular medicine (Cambridge, Mass.) 20120101

Title: Predictors of early and late outcomes after everolimus and paclitaxel-eluting coronary stents.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101

Title: Intravascular ultrasound assessment of postprocedural incomplete stent apposition.

Journal: The Journal of invasive cardiology 20120101

Title: mTOR as a target of everolimus in refractory/relapsed Hodgkin lymphoma.

Journal: Current medicinal chemistry 20120101

Title: Validation of an LC-MS/MS method to determine five immunosuppressants with deuterated internal standards including MPA.

Journal: BMC clinical pharmacology 20120101

Title: Reversible acute encephalopathy with mutism, induced by calcineurin inhibitors after renal transplantation.

Journal: Journal of nephrology 20120101

Title: Additive effectiveness of everolimus plus tamoxifen therapy in treatment of encapsulating peritoneal sclerosis.

Journal: Renal failure 20120101

Title: Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells.

Journal: Cell death & disease 20120101

Title: Everolimus with reduced-dose cyclosporine versus full-dose cyclosporine and mycophenolate in de novo renal transplant patients: a 2-year single-center experience.

Journal: Transplantation proceedings 20120101

Title: First-in-man study of simvastatin-eluting stent in de novo coronary lesions: the SIMVASTENT study.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101

Title: Bullous pemphigoid in a transplant recipient: is this a sign of allograft rejection?

Journal: European journal of dermatology : EJD 20120101

Title: Steve Jobs's cancer. Pancreatic neuroendocrine tumors are becoming more common (the bad news) and also more treatable (the good news).

Journal: Harvard health letter 20120101

Title: Delayed mTOR inhibition with low dose of everolimus reduces TGFβ expression, attenuates proteinuria and renal damage in the renal mass reduction model.

Journal: PloS one 20120101

Title: [Metastatic breast cancer. Everolimus --a drug delays the progression of the tumor].

Journal: Perspective infirmiere : revue officielle de l'Ordre des infirmieres et infirmiers du Quebec 20120101

Title: The 'Harmonizing Optimal Strategy for Treatment of coronary artery stenosis - sAfety & effectiveneSS of drug-elUting stents & antiplatelet REgimen' (HOST-ASSURE) trial: study protocol for a randomized controlled trial.

Journal: Trials 20120101

Title: Conversion from everolimus with low-exposure cyclosporine to everolimus with mycophenolate sodium maintenance therapy in kidney transplant recipients: a randomized, open-label multicenter study.

Journal: Annals of transplantation 20120101

Title: Targeting mTOR pathways in human malignancies.

Journal: Current pharmaceutical design 20120101

Title: Vascular compliance changes of the coronary vessel wall after bioresorbable vascular scaffold implantation in the treated and adjacent segments.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101

Title: Outcomes of patients treated with the everolimus-eluting stent versus the zotarolimus eluting stent in a consecutive cohort of patients at a tertiary medical center.

Journal: Vascular health and risk management 20120101

Title: [Neuroendocrine tumors: the age of targeted therapies].

Journal: Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20120101

Title: Onychopathy induced by temsirolimus, a mammalian target of rapamycin inhibitor.

Journal: Dermatology (Basel, Switzerland) 20120101

Title: Simultaneous determination of cyclosporine A, tacrolimus, sirolimus, and everolimus in whole-blood samples by LC-MS/MS.

Journal: TheScientificWorldJournal 20120101

Title: Genotype-dependent efficacy of a dual PI3K/mTOR inhibitor, NVP-BEZ235, and an mTOR inhibitor, RAD001, in endometrial carcinomas.

Journal: PloS one 20120101

Title: Preparation and in vivo evaluation of liposomal everolimus for lung carcinoma and thyroid carcinoma.

Journal: Biological & pharmaceutical bulletin 20120101

Title: BOLERO-2 - will this change practice in advanced breast cancer?

Journal: Breast cancer research : BCR 20120101

Title: Comparative vascular responses three months after paclitaxel and everolimus-eluting stent implantation in streptozotocin-induced diabetic porcine coronary arteries.

Journal: Cardiovascular diabetology 20120101

Title: Inhibition of chondrosarcoma growth by mTOR inhibitor in an in vivo syngeneic rat model.

Journal: PloS one 20120101

Title: Everolimus enhances gemcitabine-induced cytotoxicity in bladder-cancer cell lines.

Journal: Journal of toxicology and environmental health. Part A 20120101

Title: Occurrence of late acquired peri-stent contrast staining: comparison between sirolimus-eluting stents and everolimus-eluting stents.

Journal: International heart journal 20120101

Title: Successful conversion to everolimus after cytomegalovirus infection in a heart transplant recipient.

Journal: International heart journal 20120101

Title: A case of pancreatic cancer after heart transplantation.

Journal: International heart journal 20120101

Title: Current status and perspectives of targeted therapy in well-differentiated neuroendocrine tumors.

Journal: Oncology 20120101

Title: Sunitinib and everolimus in pancreatic neuroendocrine tumors.

Journal: Tumori 20120101

Title: Mid-term clinical outcomes of ACS and non-ACS patients treated with everolimus-eluting stents.

Journal: International heart journal 20120101

Title: Correcting overall survival for the impact of crossover via a rank-preserving structural failure time (RPSFT) model in the RECORD-1 trial of everolimus in metastatic renal-cell carcinoma.

Journal: Journal of biopharmaceutical statistics 20120101

Title: Everolimus and sirolimus in combination with cyclosporine have different effects on renal metabolism in the rat.

Journal: PloS one 20120101

Title: The cdk1-cyclin B complex is involved in everolimus triggered resistance in the PC3 prostate cancer cell line.

Journal: Cancer letters 20111226

Title: mTOR inhibitor therapy for patients with carcinoid.

Journal: Lancet (London, England) 20111210

Title: Everolimus plus octreotide long-acting repeatable for the treatment of advanced neuroendocrine tumours associated with carcinoid syndrome (RADIANT-2): a randomised, placebo-controlled, phase 3 study.

Journal: Lancet (London, England) 20111210

Title: Efficacy of RAD001 (everolimus) against advanced gastric cancer with peritoneal dissemination.

Journal: Investigational new drugs 20111201

Title: Long-term stable disease in metastatic renal cell carcinoma: sorafenib sequenced to sunitinib and everolimus: a case study.

Journal: Medical oncology (Northwood, London, England) 20111201

Title: Long-term response with everolimus for metastatic renal cell carcinoma refractory to sunitinib.

Journal: Medical oncology (Northwood, London, England) 20111201

Title: 3-Dimensional reconstruction of a bifurcation lesion with double wire after implantation of a second generation everolimus-eluting bioresorbable vascular scaffold.

Journal: International journal of cardiology 20111201

Title: Comparison of pharmacokinetics of the limus-eluting stents in Japanese patients.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20111201

Title: Evaluation of the MassTrak Immunosuppressant XE Kit for the determination of everolimus and cyclosporin A in human whole blood employing isotopically labeled internal standards.

Journal: Clinical chemistry and laboratory medicine 20111201

Title: Inhibitors of mTOR overcome drug resistance from topoisomerase II inhibitors in solid tumors.

Journal: Cancer letters 20111201

Title: m-TOR inhibitors: what role in liver transplantation?

Journal: Journal of hepatology 20111201

Title: Comparison of zotarolimus- versus everolimus-eluting stents in the treatment of coronary bifurcation lesions.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20111201

Title: Sequence therapy in patients with metastatic renal cell carcinoma: comparison of common targeted treatment options following failure of receptor tyrosine kinase inhibitors.

Journal: European urology 20111201

Title: Renal function in children with heart transplantation after switching to CNI-free immunosuppression with everolimus.

Journal: Pediatric transplantation 20111201

Title: Everolimus in combination with pemetrexed in patients with advanced non-small cell lung cancer previously treated with chemotherapy: a phase I study using a novel, adaptive Bayesian dose-escalation model.

Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20111201

Title: Performance of everolimus-eluting versus paclitaxel-eluting coronary stents in small vessels: results from the SPIRIT III and SPIRIT IV clinical trials.

Journal: Journal of interventional cardiology 20111201

Title: Pregnancy under everolimus-based immunosuppression.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20111201

Title: Do wound complications or lymphoceles occur more often in solid organ transplant recipients on mTOR inhibitors? A systematic review of randomized controlled trials.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20111201

Title: Late withdrawal of calcineurin inhibitors and switch to mTOR inhibitors--beneficial or too late?

Journal: Pediatric transplantation 20111201

Title: Integration of diffusion-weighted MRI data and a simple mathematical model to predict breast tumor cellularity during neoadjuvant chemotherapy.

Journal: Magnetic resonance in medicine 20111201

Title: Chromogranin A and neuron-specific enolase as prognostic markers in patients with advanced pNET treated with everolimus.

Journal: The Journal of clinical endocrinology and metabolism 20111201

Title: Autophagy in atherosclerosis: a potential drug target for plaque stabilization.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20111201

Title: Bifurcation stenting with a provisional T strategy: drug eluting stent type does matter.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20111201

Title: Rationale and design of the EXAMINATION trial: a randomised comparison between everolimus-eluting stents and cobalt-chromium bare-metal stents in ST-elevation myocardial infarction.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111201

Title: [Antihormonal therapy in breast cancer and mTOR inhibitors].

Journal: Bulletin du cancer 20111201

Title: Risk of target lesion failure in relationship to vessel angiographic geometry and stent conformability using the second generation of drug-eluting stents.

Journal: American heart journal 20111201

Title: Lipid profile changes during the first year after kidney transplantation: risk factors and influence of the immunosuppressive drug regimen.

Journal: Transplantation proceedings 20111201

Title: Head-to-head comparison of the neointimal response between metallic and bioresorbable everolimus-eluting scaffolds using optical coherence tomography.

Journal: JACC. Cardiovascular interventions 20111201

Title: Serial in vivo intravascular ultrasound-based echogenicity changes of everolimus-eluting bioresorbable vascular scaffold during the first 12 months after implantation insights from the ABSORB B trial.

Journal: JACC. Cardiovascular interventions 20111201

Title: A new era of prospective real-world safety evaluation primary report of XIENCE V USA (XIENCE V Everolimus Eluting Coronary Stent System condition-of-approval post-market study).

Journal: JACC. Cardiovascular interventions 20111201

Title: Everolimus prevents endomyocardial remodeling after heart transplantation.

Journal: Transplantation 20111127

Title: Treatment of everolimus-resistant metastatic renal cell carcinoma with VEGF-targeted therapies.

Journal: British journal of cancer 20111122

Title: Phase 1/2 study of everolimus in advanced hepatocellular carcinoma.

Journal: Cancer 20111115

Title: Decreased lymphangiogenesis and lymph node metastasis by mTOR inhibition in head and neck cancer.

Journal: Cancer research 20111115

Title: Differences in drug-eluting stents used in coronary artery disease.

Journal: The American journal of the medical sciences 20111101

Title: Activation of the phosphatidylinositol 3'-kinase/AKT pathway in neuroblastoma and its regulation by thioredoxin 1.

Journal: Human pathology 20111101

Title: Cytomegalovirus incidence between everolimus versus mycophenolate in de novo renal transplants: pooled analysis of three clinical trials.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20111101

Title: Monitoring of mycophenolic acid and kidney function during combined immunosuppressive therapy.

Journal: Clinical chemistry and laboratory medicine 20111101

Title: mTORC1 activation triggers the unfolded protein response in podocytes and leads to nephrotic syndrome.

Journal: Laboratory investigation; a journal of technical methods and pathology 20111101

Title: Elimination of norovirus in a chronic carrier under immunosuppression after heart transplantation--effect of everolimus.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20111101

Title: Role of everolimus in pancreatic neuroendocrine tumors.

Journal: Expert review of anticancer therapy 20111101

Title: [Second line AUO (Working Group Urological Oncology) study AB 35/09 on metastasized urothelial carcinoma. Phase II study with RAD001 in combination with paclitaxel for patients with metastasized urothelial carcinoma of the urinary bladder after failure of platinum-based chemotherapy (CRAD001)].

Journal: Der Urologe. Ausg. A 20111101

Title: Successful treatment of a late presentation exercise-induced spontaneous left anterior descending artery dissection.

Journal: The Journal of invasive cardiology 20111101

Title: [Management of metastatic neuroendocrine tumors].

Journal: Annales de pathologie 20111101

Title: Everolimus-induced loss of wound strength can be prevented by a short postoperative delay in its administration.

Journal: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20111101

Title: De novo use of everolimus with elimination or minimization of cyclosporine in renal transplant recipients.

Journal: Transplantation proceedings 20111101

Title: Impact of lesion length and vessel size on clinical outcomes after percutaneous coronary intervention with everolimus- versus paclitaxel-eluting stents pooled analysis from the SPIRIT (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) and COMPARE (Second-generation everolimus-eluting and paclitaxel-eluting stents in real-life practice) Randomized Trials.

Journal: JACC. Cardiovascular interventions 20111101

Title: Second-generation everolimus-eluting stents and the beat goes on?

Journal: JACC. Cardiovascular interventions 20111101

Title: Unprotected left main stenting with a second-generation drug-eluting stent: one-year outcomes of the LEMAX Pilot study.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111030

Title: Everolimus-eluting versus sirolimus-eluting stents in patients undergoing percutaneous coronary intervention: the EXCELLENT (Efficacy of Xience/Promus Versus Cypher to Reduce Late Loss After Stenting) randomized trial.

Journal: Journal of the American College of Cardiology 20111025

Title: Head-to-head randomized comparisons of limus-eluting coronary stents: pursuing excellence or flying too high?

Journal: Journal of the American College of Cardiology 20111025

Title: Impact of the everolimus-eluting stent on stent thrombosis: a meta-analysis of 13 randomized trials.

Journal: Journal of the American College of Cardiology 20111004

Title: Evaluation of the second generation of a bioresorbable everolimus-eluting vascular scaffold for the treatment of de novo coronary artery stenosis: 12-month clinical and imaging outcomes.

Journal: Journal of the American College of Cardiology 20111004

Title: The magic of disappearing stents.

Journal: Journal of the American College of Cardiology 20111004

Title: North Central Cancer Treatment Group Phase I trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme.

Journal: International journal of radiation oncology, biology, physics 20111001

Title: Assessment of the serial changes of vessel wall contents in atherosclerotic coronary lesion with bioresorbable everolimus-eluting vascular scaffolds using Shin's method: an IVUS study.

Journal: The international journal of cardiovascular imaging 20111001

Title: Natural history, management and pharmacokinetics of everolimus-induced-oral ulcers: insights into compliance issues.

Journal: European journal of cancer (Oxford, England : 1990) 20111001

Title: Tissue coverage of a hydrophilic polymer-coated zotarolimus-eluting stent vs. a fluoropolymer-coated everolimus-eluting stent at 13-month follow-up: an optical coherence tomography substudy from the RESOLUTE All Comers trial.

Journal: European heart journal 20111001

Title: Efficacy of re-challenging metastatic renal cell carcinoma with mTOR inhibitors.

Journal: Acta oncologica (Stockholm, Sweden) 20111001

Title: Leflunomide with low-dose everolimus for treatment of Kaposi's sarcoma in a renal allograft recipient.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111001

Title: Serum levels after everolimus-stent implantation and paclitaxel-balloon angioplasty in an infant with recurrent pulmonary vein obstruction after repaired total anomalous pulmonary venous connection.

Journal: Pediatric cardiology 20111001

Title: Everolimus tablets for patients with subependymal giant cell astrocytoma.

Journal: Expert opinion on pharmacotherapy 20111001

Title: Induction of autophagy with catalytic mTOR inhibitors reduces huntingtin aggregates in a neuronal cell model.

Journal: Journal of neurochemistry 20111001

Title: Role of biological targeted therapies in gastroenteropancreatic neuroendocrine tumours.

Journal: Endocrine 20111001

Title: Clinical presentation and management of mTOR inhibitor-associated stomatitis.

Journal: Oral oncology 20111001

Title: New target therapies for patients with neuroendocrine tumors of the pancreas.

Journal: Expert review of gastroenterology & hepatology 20111001

Title: [The BASKET-PROVE study].

Journal: Giornale italiano di cardiologia (2006) 20111001

Title: Sunitinib re-challenge in metastatic renal cell carcinoma treated sequentially with tyrosine kinase inhibitors and everolimus.

Journal: Anticancer research 20111001

Title: Bioresorbable polymeric vascular scaffolds: a cautionary tale.

Journal: Circulation. Cardiovascular interventions 20111001

Title: Comparison of everolimus- and sirolimus-eluting stents in patients with long coronary artery lesions: a randomized LONG-DES-III (Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-III) Trial.

Journal: JACC. Cardiovascular interventions 20111001

Title: Comparison of everolimus- and paclitaxel-eluting stents in patients with acute and stable coronary syndromes: pooled results from the SPIRIT (A Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) and COMPARE (A Trial of Everolimus-Eluting Stents and Paclitaxel-Eluting Stents for Coronary Revascularization in Daily Practice) Trials.

Journal: JACC. Cardiovascular interventions 20111001

Title: Should everolimus-eluting stents be preferred in patients with acute and stable coronary syndromes?

Journal: JACC. Cardiovascular interventions 20111001

Title: Three-dimensional reconstruction of the post-dilated ABSORB everolimus-eluting bioresorbable vascular scaffold in a true bifurcation lesion for flow restoration.

Journal: JACC. Cardiovascular interventions 20111001

Title: Pediatric kidney transplantation followed by de novo therapy with everolimus, low-dose cyclosporine A, and steroid elimination: 3-year data.

Journal: Transplantation 20110927

Title: [RAD001 reverses radio-resistance and exerts synergistic tumor inhibition with 5-fluorouracil].

Journal: Zhonghua yi xue za zhi 20110927

Title: Biodegradable polymer versus permanent polymer drug-eluting stents and everolimus- versus sirolimus-eluting stents in patients with coronary artery disease: 3-year outcomes from a randomized clinical trial.

Journal: Journal of the American College of Cardiology 20110920

Title: A phase 1 study of everolimus and sorafenib for metastatic clear cell renal cell carcinoma.

Journal: Cancer 20110915

Title: Limitations in small intestinal neuroendocrine tumor therapy by mTor kinase inhibition reflect growth factor-mediated PI3K feedback loop activation via ERK1/2 and AKT.

Journal: Cancer 20110915

Title: Impact of de novo everolimus-based immunosuppression on incisional complications in heart transplantation.

Journal: Transplantation 20110915

Title: Acute cholecystitis in a patient with metastatic renal cell carcinoma treated with everolimus.

Journal: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20110901

Title: Optical coherence evaluation of everolimus-eluting stents 8 months after implantation.

Journal: Heart (British Cardiac Society) 20110901

Title: Combination of everolimus with calcineurin inhibitor medication resulted in post-transplant haemolytic uraemic syndrome in lung transplant recipients--a case series.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110901

Title: Interaction of sirolimus and everolimus with hepatic and intestinal organic anion-transporting polypeptide transporters.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110901

Title: [Metastatic renal cell cancer in Germany in 2010. Impact of different target therapies].

Journal: Der Urologe. Ausg. A 20110901

Title: New therapeutic options for metastatic malignant insulinomas.

Journal: Clinical endocrinology 20110901

Title: Paronychia and pyogenic granuloma induced by new anticancer mTOR inhibitors.

Journal: Acta dermato-venereologica 20110901

Title: Mesenchymal stem cells and carcinoma-associated fibroblasts sensitize breast cancer cells in 3D cultures to kinase inhibitors.

Journal: International journal of oncology 20110901

Title: Managing refractory metastatic renal cell carcinoma: a RECORD spinning on a tilted AXIS.

Journal: Clinical genitourinary cancer 20110901

Title: The mTOR inhibitor RAD001 sensitizes tumor cells to the cytotoxic effect of carboplatin in breast cancer in vitro.

Journal: Anticancer research 20110901

Title: Long-term experience with everolimus in kidney transplantation in the United States.

Journal: Transplantation proceedings 20110901

Title: A retrospective 12-month study of conversion to everolimus in lung transplant recipients.

Journal: Transplantation proceedings 20110901

Title: Everolimus and sunitinib: from mouse models to treatment of pancreatic neuroendocrine tumors.

Journal: Future oncology (London, England) 20110901

Title: Serial analysis of the malapposed and uncovered struts of the new generation of everolimus-eluting bioresorbable scaffold with optical coherence tomography.

Journal: JACC. Cardiovascular interventions 20110901

Title: Total aorto-ostial chronic occlusion of the right coronary artery successfully recanalized via retrograde approach.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110901

Title: [Everolimus-eluting stent].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20110901

Title: [Effect of RAD001 or plus LBH589 on the proliferation, apoptosis and drug resistance in chemoresistant acute myeloid leukemic cells].

Journal: Zhonghua yi xue za zhi 20110830

Title: Conversion of long-term kidney transplant recipients from calcineurin inhibitor therapy to everolimus: a randomized, multicenter, 24-month study.

Journal: Transplantation 20110827

Title: Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1/2 study in patients with myelofibrosis.

Journal: Blood 20110825

Title: Randomized comparison of everolimus-eluting stent versus sirolimus-eluting stent implantation for de novo coronary artery disease in patients with diabetes mellitus (ESSENCE-DIABETES): results from the ESSENCE-DIABETES trial.

Journal: Circulation 20110823

Title: Differential clinical responses to everolimus-eluting and Paclitaxel-eluting coronary stents in patients with and without diabetes mellitus.

Journal: Circulation 20110823

Title: Is diabetes the achilles' heel of limus-eluting stents?

Journal: Circulation 20110823

Title: Inhibition of mammalian target of rapamycin signaling by everolimus induces senescence in adult T-cell leukemia/lymphoma and apoptosis in peripheral T-cell lymphomas.

Journal: International journal of cancer 20110815

Title: Everolimus-eluting versus paclitaxel-eluting stents for treatment of bare metal stent restenosis.

Journal: The American journal of cardiology 20110815

Title: Everolimus and long-term outcomes in renal transplantation: seeking an optimal strategy for immunosuppression.

Journal: Transplantation 20110815

Title: Everolimus and long-term outcomes in renal transplantation.

Journal: Transplantation 20110815

Title: Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110810

Title: The mammalian target of rapamycin inhibitor everolimus (RAD001) in early breast cancer: results of a pre-operative study.

Journal: Breast cancer research and treatment 20110801

Title: Are we missing the mTOR target in breast cancer?

Journal: Breast cancer research and treatment 20110801

Title: Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis.

Journal: Journal of hepatology 20110801

Title: The management of subependymal giant cell tumors in tuberous sclerosis: a clinician's perspective.

Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20110801

Title: Conversion to everolimus in maintenance liver transplant patients: a multicenter, retrospective analysis.

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20110801

Title: Angiographic outcomes with biodegradable polymer and permanent polymer drug-eluting stents.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110801

Title: Low stent thrombosis risk with the XIENCE V® Everolimus-Eluting Coronary Stent: evidence from randomized and single-arm clinical trials.

Journal: Journal of interventional cardiology 20110801

Title: Focus.

Journal: Journal of hepatology 20110801

Title: Cholesterol esters as growth regulators of lymphocytic leukaemia cells.

Journal: Cell proliferation 20110801

Title: First clinical trial of nitinol self-expanding everolimus-eluting stent implantation for peripheral arterial occlusive disease.

Journal: Journal of vascular surgery 20110801

Title: The use of everolimus in pediatric liver transplant recipients: first experience in a single center.

Journal: Pediatric transplantation 20110801

Title: Evaluation of performance of new, isotopically labeled internal standard ([13c2d4]RAD001) for everolimus using a novel high-performance liquid chromatography tandem mass spectrometry method.

Journal: Therapeutic drug monitoring 20110801

Title: mTOR inhibitors in advanced renal cell carcinoma.

Journal: Hematology/oncology clinics of North America 20110801

Title: How can we miss you, if you will never leave? Biodegradable stents.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110801

Title: Everolimus-eluting versus sirolimus-eluting stents: a meta-analysis of randomized trials.

Journal: Circulation. Cardiovascular interventions 20110801

Title: A phase II trial of bevacizumab plus everolimus for patients with refractory metastatic colorectal cancer.

Journal: The oncologist 20110801

Title: Everolimus vs. rapamycin for treating diabetic nephropathy in diabetic mouse model.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20110801

Title: Everolimus: an mTOR inhibitor for the treatment of tuberous sclerosis.

Journal: Expert review of anticancer therapy 20110801

Title: A shining light in the darkness for the treatment of pancreatic neuroendocrine tumors.

Journal: Cancer discovery 20110801

Title: Everolimus for cardiac allograft vasculopathy--every patient, at any time?

Journal: Transplantation 20110727

Title: Effect of everolimus introduction on cardiac allograft vasculopathy--results of a randomized, multicenter trial.

Journal: Transplantation 20110727

Title: [Adverse effects of new oncologic therapies].

Journal: Praxis 20110727

Title: PIK3CA mutation, but not PTEN loss of function, determines the sensitivity of breast cancer cells to mTOR inhibitory drugs.

Journal: Oncogene 20110721

Title: 6-month clinical outcomes following implantation of the bioresorbable everolimus-eluting vascular scaffold in vessels smaller or larger than 2.5 mm.

Journal: Journal of the American College of Cardiology 20110712

Title: Temporal changes of coronary artery plaque located behind the struts of the everolimus eluting bioresorbable vascular scaffold.

Journal: The international journal of cardiovascular imaging 20110701

Title: Twelve-month clinical outcomes of everolimus-eluting stent as compared to paclitaxel- and sirolimus-eluting stent in patients undergoing percutaneous coronary interventions. A meta-analysis of randomized clinical trials.

Journal: International journal of cardiology 20110701

Title: Percutaneous intervention of a thrombotic-occluded saphenous vein graft successfully treated using the undersized stent approach to prevent distal embolization.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110701

Title: An investigator-driven study of everolimus in surgical lung biopsy confirmed idiopathic pulmonary fibrosis.

Journal: Respirology (Carlton, Vic.) 20110701

Title: Comparison of in vivo acute stent recoil between the bioresorbable everolimus-eluting coronary scaffolds (revision 1.0 and 1.1) and the metallic everolimus-eluting stent.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110701

Title: Primum non nocere: safety in clinical trials for IPF.

Journal: Respirology (Carlton, Vic.) 20110701

Title: Meta-analysis of everolimus-eluting stent as compared to sirolimus-eluting stent in patients undergoing percutaneous coronary interventions: an update.

Journal: International journal of cardiology 20110701

Title: Phase I trial of capecitabine plus everolimus (RAD001) in patients with previously treated metastatic gastric cancer.

Journal: Cancer chemotherapy and pharmacology 20110701

Title: Continuing response to subsequent treatment lines with tyrosine kinase inhibitors in an adolescent with metastatic renal cell carcinoma.

Journal: Journal of pediatric hematology/oncology 20110701

Title: High-throughput LC-MS/MS method for monitoring sirolimus and everolimus in the routine clinical laboratory.

Journal: Clinical chemistry and laboratory medicine 20110701

Title: An adjusted indirect comparison of everolimus and sorafenib therapy in sunitinib-refractory metastatic renal cell carcinoma patients using repeated matched samples.

Journal: Expert opinion on pharmacotherapy 20110701

Title: The activity of trabectedin as a single agent or in combination with everolimus for clear cell carcinoma of the ovary.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110701

Title: Testing the strength of biodegradable stents.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110701

Title: [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma].

Journal: Aktuelle Urologie 20110701

Title: Successful stent implantation guided by intravascular ultrasound and a Doppler guidewire without contrast injection in a patient with allergy to iodinated contrast media.

Journal: The Journal of invasive cardiology 20110701

Title: Clinical and angiographic outcomes of elderly patients treated with everolimus-eluting versus paclitaxel-eluting stents: three-year results from the SPIRIT III randomised trial.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110701

Title: 2-year follow-up of a randomized controlled trial of everolimus- and paclitaxel-eluting stents for coronary revascularization in daily practice. COMPARE (Comparison of the everolimus eluting XIENCE-V stent with the paclitaxel eluting TAXUS LIBERTÉ stent in all-comers: a randomized open label trial).

Journal: Journal of the American College of Cardiology 20110628

Title: Randomized comparison of everolimus- and paclitaxel-eluting stents. 2-year follow-up from the SPIRIT (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) IV trial.

Journal: Journal of the American College of Cardiology 20110628

Title: Second-generation drug-eluting stents. Moving the field forward.

Journal: Journal of the American College of Cardiology 20110628

Title: A proof of concept phase II non-inferiority criterion.

Journal: Statistics in medicine 20110615

Title: Outcomes after unrestricted use of everolimus-eluting stent compared to paclitaxel- and sirolimus-eluting stents.

Journal: The American journal of cardiology 20110615

Title: Comparison of everolimus-eluting stent with paclitaxel-eluting stent in long chronic total occlusions.

Journal: The American journal of cardiology 20110615

Title: Thrombotic thrombocytopenic purpura associated with everolimus use in a renal transplant patient.

Journal: International urology and nephrology 20110601

Title: Four-year clinical follow-up of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with de novo coronary artery lesions: the SPIRIT II trial.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110601

Title: Donor pre-treatment with everolimus or cyclosporine does not reduce ischaemia-reperfusion injury in a rat kidney transplant model.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110601

Title: Dramatic tumor response to everolimus for malignant epithelioid angiomyolipoma.

Journal: Japanese journal of clinical oncology 20110601

Title: mTOR inhibition, a potential novel approach for bronchial carcinoids.

Journal: Endocrine-related cancer 20110601

Title: The real world experience of the everolimus-eluting coronary stent system: audit of everolimus-eluting coronary stents.

Journal: Journal of interventional cardiology 20110601

Title: Impact of combined HDAC and mTOR inhibition on adhesion, migration and invasion of prostate cancer cells.

Journal: Clinical & experimental metastasis 20110601

Title: Mammalian target of rapamycin expression in poorly differentiated endocrine carcinoma: clinical and therapeutic future challenges.

Journal: Targeted oncology 20110601

Title: Treatment of metastatic renal cell carcinoma and renal pelvic cancer.

Journal: Clinical and experimental nephrology 20110601

Title: Management of adverse events associated with the use of everolimus in patients with advanced renal cell carcinoma.

Journal: European journal of cancer (Oxford, England : 1990) 20110601

Title: Everolimus induces rapid plasma glucose normalization in insulinoma patients by effects on tumor as well as normal tissues.

Journal: The oncologist 20110601

Title: Everolimus augments the effects of sorafenib in a syngeneic orthotopic model of hepatocellular carcinoma.

Journal: Molecular cancer therapeutics 20110601

Title: Common toxicities of mammalian target of rapamycin inhibitors.

Journal: Targeted oncology 20110601

Title: Everolimus plus dosage reduction of cyclosporine in cardiac transplant recipients with chronic kidney disease: a two-year follow-up study.

Journal: Transplantation proceedings 20110601

Title: Calcineurin inhibitor-free immunosuppression using everolimus (Certican) after heart transplantation: 2 years' follow-up from the University Hospital Münster.

Journal: Transplantation proceedings 20110601

Title: Efficacy and safety of sirolimus and everolimus in heart transplant patients: a retrospective analysis.

Journal: Transplantation proceedings 20110601

Title: The impact of patient and lesion complexity on clinical and angiographic outcomes after revascularization with zotarolimus- and everolimus-eluting stents: a substudy of the RESOLUTE All Comers Trial (a randomized comparison of a zotarolimus-eluting stent with an everolimus-eluting stent for percutaneous coronary intervention).

Journal: Journal of the American College of Cardiology 20110531

Title: Prospective study of everolimus with calcineurin inhibitor-free immunosuppression in maintenance heart transplant patients: results at 2 years.

Journal: Transplantation 20110527

Title: Everolimus and minimization of cyclosporine in renal transplantation: 24-month follow-up of the EVEREST study.

Journal: Transplantation 20110527

Title: Long-term comparison of everolimus-eluting and sirolimus-eluting stents for coronary revascularization.

Journal: Journal of the American College of Cardiology 20110524

Title: Advances in pancreatic neuroendocrine tumor treatment.

Journal: The New England journal of medicine 20110512

Title: Everolimus- and temsirolimus-associated enteritis: report of three cases.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110510

Title: Everolimus interferes with the inflammatory phase of healing in experimental colonic anastomoses.

Journal: The Journal of surgical research 20110501

Title: Therapy of sclerodermatous chronic graft-versus-host disease with mammalian target of rapamycin inhibitors.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110501

Title: Somatostatin analogues for treatment of polycystic liver disease.

Journal: Current opinion in gastroenterology 20110501

Title: Predictors of long-term renal function after conversion to proliferation signal inhibitors in long-term heart transplant recipients.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20110501

Title: Lack of compensatory pAKT activation and eIF4E phosphorylation of lymphoma cells towards mTOR inhibitor, RAD001.

Journal: European journal of cancer (Oxford, England : 1990) 20110501

Title: Effects of mTOR inhibitor everolimus (RAD001) on bladder cancer cells.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110501

Title: Patient-reported outcomes in a phase iii study of everolimus versus placebo in patients with metastatic carcinoma of the kidney that has progressed on vascular endothelial growth factor receptor tyrosine kinase inhibitor therapy.

Journal: The oncologist 20110501

Title: Regression of a cardiac rhabdomyoma in a patient receiving everolimus.

Journal: Pediatrics 20110501

Title: Everolimus for the treatment of advanced renal cell carcinoma.

Journal: Expert opinion on pharmacotherapy 20110501

Title: Predictors of death or myocardial infarction, ischaemic-driven revascularisation, and major adverse cardiovascular events following everolimus-eluting or paclitaxel-eluting stent deployment: pooled analysis from the SPIRIT II, III, IV and COMPARE trials.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501

Title: PLATINUM QCA: a prospective, multicentre study assessing clinical, angiographic, and intravascular ultrasound outcomes with the novel platinum chromium thin-strut PROMUS Element everolimus-eluting stent in de novo coronary stenoses.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501

Title: Impact of drug-eluting stent type on periprocedural myocardial necrosis.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501

Title: Usefulness of rotational atherectomy in preventing polymer damage of everolimus-eluting stent in calcified coronary artery.

Journal: JACC. Cardiovascular interventions 20110501

Title: Once-a-day administration of everolimus is safe in de novo renal transplant recipients: 1-year results of a pilot study.

Journal: Transplantation proceedings 20110501

Title: Optical coherence tomography (OCT) in PCI for in-stent restenosis (ISR): rationale and design of the SEDUCE (Safety and Efficacy of a Drug elUting balloon in Coronary artery rEstenosis) study.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501

Title: A prospective randomised study using optical coherence tomography to assess endothelial coverage and neointimal proliferation at 6-months after implantation of a coronary everolimus-eluting stent compared with a bare metal stent postdilated with a paclitaxel-eluting balloon (OCTOPUS Trial): rationale, design and methods.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501

Title: [Novelties in the treatment for advanced renal-cell cancer].

Journal: Orvosi hetilap 20110424

Title: Recent studies show promise for treating rare pancreatic tumors.

Journal: Journal of the National Cancer Institute 20110420

Title: A prospective, randomized evaluation of a novel everolimus-eluting coronary stent: the PLATINUM (a Prospective, Randomized, Multicenter Trial to Assess an Everolimus-Eluting Coronary Stent System [PROMUS Element] for the Treatment of Up to Two de Novo Coronary Artery Lesions) trial.

Journal: Journal of the American College of Cardiology 20110419

Title: Unrestricted randomised use of two new generation drug-eluting coronary stents: 2-year patient-related versus stent-related outcomes from the RESOLUTE All Comers trial.

Journal: Lancet (London, England) 20110409

Title: Long-term safety and efficacy of drug-eluting stents.

Journal: Lancet (London, England) 20110409

Title: A phase II study of everolimus in combination with imatinib for previously treated advanced renal carcinoma.

Journal: Investigational new drugs 20110401

Title: Melanoma: from darkness to promise.

Journal: American journal of clinical oncology 20110401

Title: Development and characterization of clinically relevant tumor models from patients with renal cell carcinoma.

Journal: European urology 20110401

Title: Evaluation of QMS everolimus assay using Hitachi 917 Analyzer: comparison with liquid chromatography/mass spectrometry.

Journal: Therapeutic drug monitoring 20110401

Title: The novel Raf inhibitor Raf265 decreases Bcl-2 levels and confers TRAIL-sensitivity to neuroendocrine tumour cells.

Journal: Endocrine-related cancer 20110401

Title: The prognostic utility of the SYNTAX score on 1-year outcomes after revascularization with zotarolimus- and everolimus-eluting stents: a substudy of the RESOLUTE All Comers Trial.

Journal: JACC. Cardiovascular interventions 20110401

Title: Comparison between the first and second generation bioresorbable vascular scaffolds: a six month virtual histology study.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110401

Title: mTOR inhibitors in the treatment of subependymal giant-cell astrocytomas associated with tuberous sclerosis.

Journal: Neurosurgery 20110401

Title: Chromophobe renal cell carcinoma with prolonged response to sequential sunitinib and everolimus.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110320

Title: Translational medicine: Cancer lessons from mice to humans.

Journal: Nature 20110317

Title: Long-term (three-year) safety and efficacy of everolimus-eluting stents compared to paclitaxel-eluting stents (from the SPIRIT III Trial).

Journal: The American journal of cardiology 20110315

Title: Three-year results of safety and efficacy of the everolimus-eluting coronary stent in women (from the SPIRIT III randomized clinical trial).

Journal: The American journal of cardiology 20110315

Title: Pancreatic neuroendocrine tumors: role of novel agents. Highlights from the '2011 ASCO Gastrointestinal Cancers Symposium'. San Francisco, CA, USA. January 20-22, 2011.

Journal: JOP : Journal of the pancreas 20110309

Title: Everolimus-based, calcineurin-inhibitor-free regimen in recipients of de-novo kidney transplants: an open-label, randomised, controlled trial.

Journal: Lancet (London, England) 20110305

Title: Immunosuppression without calcineurin inhibition: by ZEUS.

Journal: Lancet (London, England) 20110305

Title: Comparative assessment of mammalian target of rapamycin inhibitor-eluting stents in the treatment of coronary artery bifurcation lesions: the CASTOR-Bifurcation registry.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110301

Title: Leukemias induced by altered TRK-signaling are sensitive to mTOR inhibitors in preclinical models.

Journal: Annals of hematology 20110301

Title: Cyclosporin A, but not everolimus, inhibits DNA repair mediated by calcineurin: implications for tumorigenesis under immunosuppression.

Journal: Experimental dermatology 20110301

Title: Primary percutaneous coronary intervention of an unprotected left main using mini-crush drug-eluting stents facilitated by intracoronary reteplase.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110301

Title: Noninfectious pneumonitis in a patient with renal cell carcinoma treated with everolimus.

Journal: Oncology nursing forum 20110301

Title: CYP3A5 genotype does not influence everolimus in vitro metabolism and clinical pharmacokinetics in renal transplant recipients.

Journal: Transplantation 20110301

Title: Potential of mTOR inhibitors for the treatment of subependymal giant cell astrocytomas in tuberous sclerosis complex.

Journal: Aging 20110301

Title: Prospective randomized comparison of sirolimus- or everolimus-eluting stent to treat bifurcated lesions by provisional approach.

Journal: JACC. Cardiovascular interventions 20110301

Title: Future directions of mammalian target of rapamycin (mTOR) inhibitor therapy in renal cell carcinoma.

Journal: Targeted oncology 20110301

Title: Inhibitory effects of the HDAC inhibitor valproic acid on prostate cancer growth are enhanced by simultaneous application of the mTOR inhibitor RAD001.

Journal: Life sciences 20110227

Title: mTOR inhibitor treatment of pancreatic cancer in a patient With Peutz-Jeghers syndrome.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110220

Title: Combination mTOR and IGF-1R inhibition: phase I trial of everolimus and figitumumab in patients with advanced sarcomas and other solid tumors.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110215

Title: Everolimus for advanced pancreatic neuroendocrine tumors.

Journal: The New England journal of medicine 20110210

Title: Promising advances in the treatment of malignant pancreatic endocrine tumors.

Journal: The New England journal of medicine 20110210

Title: Everolimus and giant-cell astrocytomas in tuberous sclerosis.

Journal: The New England journal of medicine 20110210

Title: Everolimus and giant-cell astrocytomas in tuberous sclerosis.

Journal: The New England journal of medicine 20110210

Title: Integrating bevacizumab, everolimus, and lapatinib into current neoadjuvant chemotherapy regimen for primary breast cancer. Safety results of the GeparQuinto trial.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20110201

Title: Comparison of blood sirolimus, tacrolimus and everolimus concentrations measured by LC-MS/MS, HPLC-UV and immunoassay methods.

Journal: Clinical biochemistry 20110201

Title: A phase I study of bevacizumab (B) in combination with everolimus (E) and erlotinib (E) in advanced cancer (BEE).

Journal: Cancer chemotherapy and pharmacology 20110201

Title: mTOR inhibitors and sorafenib for recurrent heptocellular carcinoma after orthotopic liver transplantation.

Journal: Journal of hepatology 20110201

Title: Combined targeting of the VEGFr/EGFr and the mammalian target of rapamycin (mTOR) signaling pathway delays cell cycle progression and alters adhesion behavior of prostate carcinoma cells.

Journal: Cancer letters 20110201

Title: A comparative assessment by optical coherence tomography of the performance of the first and second generation of the everolimus-eluting bioresorbable vascular scaffolds.

Journal: European heart journal 20110201

Title: A phase II trial of the oral mTOR inhibitor everolimus in relapsed aggressive lymphoma.

Journal: Leukemia 20110201

Title: Clinical safety and efficacy of everolimus-eluting stents compared to paclitaxel-eluting stents in patients with coronary artery disease.

Journal: Annals of medicine 20110201

Title: Systemic influence of immunosuppressive drugs on small and large bowel transport and barrier function.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20110201

Title: Infected coronary artery pseudoaneurysm after repeated percutaneous coronary intervention.

Journal: The Annals of thoracic surgery 20110201

Title: Total recall of radiotherapy with mTOR inhibitors: a novel and potentially frequent side-effect?

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20110201

Title: Primary everolimus-eluting stenting versus balloon angioplasty with bailout bare metal stenting of long infrapopliteal lesions for treatment of critical limb ischemia.

Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20110201

Title: Targeted therapies for the treatment of metastatic renal cell carcinoma: clinical evidence.

Journal: The oncologist 20110201

Title: Beyond traditional outcomes: improving quality of life in patients with renal cell carcinoma.

Journal: The oncologist 20110201

Title: Treatment-associated adverse event management in the advanced renal cell carcinoma patient treated with targeted therapies.

Journal: The oncologist 20110201

Title: The SPIRIT V study: a clinical evaluation of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with de novo coronary artery lesions.

Journal: JACC. Cardiovascular interventions 20110201

Title: [Types and characteristic features of drug-eluting stents].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20110201

Title: Ten-month laryngeal allograft survival with use of pulsed everolimus and anti-alphabeta T-cell receptor antibody immunosuppression.

Journal: The Annals of otology, rhinology, and laryngology 20110201

Title: mTOR inhibitors and autosomal dominant polycystic kidney disease.

Journal: The New England journal of medicine 20110120

Title: mTOR inhibitors and autosomal dominant polycystic kidney disease.

Journal: The New England journal of medicine 20110120

Title: mTOR inhibitors and autosomal dominant polycystic kidney disease.

Journal: The New England journal of medicine 20110120

Title: Haplotypic arrangement in CYP3A locus is associated with side effects of proliferative signal inhibitors in renal transplant recipients.

Journal: Transplantation 20110115

Title: The role of CYP3A5 genotypes in dose requirements of tacrolimus and everolimus after heart transplantation.

Journal: Clinical transplantation 20110101

Title: Everolimus and PTK/ZK show synergistic growth inhibition in the orthotopic BL16/BL6 murine melanoma model.

Journal: Cancer chemotherapy and pharmacology 20110101

Title: Calcineurin inhibitor sparing regimens using m-target of rapamycin inhibitors: an opportunity to improve cardiovascular risk following kidney transplantation?

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20110101

Title: Regression of subependymal giant cell astrocytomas with RAD001 (Everolimus) in tuberous sclerosis complex.

Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20110101

Title: Evaluation of the mTOR inhibitor, everolimus, in combination with cytotoxic antitumor agents using human tumor models in vitro and in vivo.

Journal: Anti-cancer drugs 20110101

Title: The mammalian target of rapamycin inhibitor RAD001 (everolimus) synergizes with chemotherapeutic agents, ionizing radiation and proteasome inhibitors in pre-B acute lymphocytic leukemia.

Journal: Haematologica 20110101

Title: Phase III trial of everolimus in metastatic renal cell carcinoma: subgroup analysis of Japanese patients from RECORD-1.

Journal: Japanese journal of clinical oncology 20110101

Title: Age and sex differences in the effects of the immunosuppressants cyclosporine, sirolimus and everolimus on rat brain metabolism.

Journal: Neurotoxicology 20110101

Title: Phase I trial of oral mTOR inhibitor everolimus in combination with trastuzumab and vinorelbine in pre-treated patients with HER2-overexpressing metastatic breast cancer.

Journal: Breast cancer research and treatment 20110101

Title: The relationship between late lumen loss and restenosis among various drug-eluting stents: a systematic review and meta-regression analysis of randomized clinical trials.

Journal: Atherosclerosis 20110101

Title: Tolerability of everolimus-based immunosuppression in maintenance liver transplant recipients.

Journal: Clinical transplantation 20110101

Title: Control of carcinoid syndrome with everolimus.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20110101

Title: Prolonged survival in renal transplant recipient with advanced renal cell carcinoma by everolimus and sorafenib.

Journal: Nephrology (Carlton, Vic.) 20110101

Title: Everolimus: a new mammalian target of rapamycin inhibitor for the treatment of advanced renal cell carcinoma.

Journal: The Annals of pharmacotherapy 20110101

Title: Two-dose-level confirmatory study of the pharmacokinetics and tolerability of everolimus in Chinese patients with advanced solid tumors.

Journal: Journal of hematology & oncology 20110101

Title: Good outcomes with cyclosporine very low exposure with everolimus high exposure in renal transplant patients.

Journal: Journal of nephrology 20110101

Title: Everolimus resolving hypoglycemia, producing hyperglycemia, and necessitating insulin use in a patient with diabetes and nonresectable malignant insulinoma.

Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20110101

Title: Clinical evidence on the use of anti-mTOR drugs in renal transplantation.

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101

Title: Response to mTOR inhibition: activity of eIF4E predicts sensitivity in cell lines and acquired changes in eIF4E regulation in breast cancer.

Journal: Molecular cancer 20110101

Title: Retrospective analyses of patient characteristics having predictive impact on survival under everolimus.

Journal: Onkologie 20110101

Title: Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer.

Journal: Breast cancer research : BCR 20110101

Title: [Immunosuppressive agents in kidney transplantation].

Journal: Nihon Jinzo Gakkai shi 20110101

Title: [Autosomal dominant polycystic kidney disease].

Journal: Nihon Jinzo Gakkai shi 20110101

Title: Conversion from sirolimus to everolimus in kidney transplant recipients receiving a calcineurin-free regimen.

Journal: Clinical transplantation 20110101

Title: The impact of new generation drug-eluting stent implantation on patients with chronic kidney disease and a single lesion in the proximal segment of the left anterior descending artery.

Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20110101

Title: Rapid estimation of whole blood everolimus concentrations using architect sirolimus immunoassay and mathematical equations: comparison with everolimus values determined by liquid chromatography/mass spectrometry.

Journal: Journal of clinical laboratory analysis 20110101

Title: [Breast cancer therapy with combination of endocrine and target drugs].

Journal: Voprosy onkologii 20110101

Title: Efficacy of temsirolimus after previous treatment with sunitinib, sorafenib or everolimus in advanced renal cell cancer.

Journal: Oncology 20110101

Title: The combination of RAD001 and NVP-BEZ235 exerts synergistic anticancer activity against non-small cell lung cancer in vitro and in vivo.

Journal: PloS one 20110101

Title: Determination of blood everolimus concentrations in kidney and liver transplant recipients using the sirolimus antibody conjugated magnetic immunoassay (ACMIA).

Journal: Clinical laboratory 20110101

Title: Everolimus in clinical practice in long-term liver transplantation: an observational study.

Journal: Transplantation proceedings 20110101

Title: Effectiveness and safety of everolimus in the treatment of autoimmune hepatitis related to anti-hepatitis C virus therapy after liver transplant: three case reports.

Journal: Transplantation proceedings 20110101

Title: Conversion to everolimus in liver transplant patients with renal dysfunction.

Journal: Transplantation proceedings 20110101

Title: Long-term use of everolimus in lung transplant patients.

Journal: Transplantation proceedings 20110101

Title: Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis.

Journal: BMC cancer 20110101

Title: c-Myc dependent expression of pro-apoptotic Bim renders HER2-overexpressing breast cancer cells dependent on anti-apoptotic Mcl-1.

Journal: Molecular cancer 20110101

Title: Economic evaluation of everolimus versus sorafenib for the treatment of metastatic renal cell carcinoma after failure of first-line sunitinib.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20110101

Title: The combination of gefitinib and RAD001 inhibits growth of HER2 overexpressing breast cancer cells and tumors irrespective of trastuzumab sensitivity.

Journal: BMC cancer 20110101

Title: Neoadjuvant chemotherapy and targeted therapies: a promising strategy.

Journal: Journal of the National Cancer Institute. Monographs 20110101

Title: [Metastatic renal cell carcinoma treated with everolimus--data from the RENIS Clinical Registry].

Journal: Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20110101

Title: Concurrent HDAC and mTORC1 inhibition attenuate androgen receptor and hypoxia signaling associated with alterations in microRNA expression.

Journal: PloS one 20110101

Title: Everolimus and long acting octreotide as a volume reducing treatment of polycystic livers (ELATE): study protocol for a randomized controlled trial.

Journal: Trials 20110101

Title: S6K1 and 4E-BP1 are independent regulated and control cellular growth in bladder cancer.

Journal: PloS one 20110101

Title: Phase I-II study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell cancer.

Journal: BMC cancer 20110101

Title: Two cases of everolimus-associated interstitial pneumonia in patients with renal cell carcinoma.

Journal: Internal medicine (Tokyo, Japan) 20110101

Title: Pulmonary embolism and reactivation of tuberculosis during everolimus therapy in a kidney transplant recipient.

Journal: Annals of transplantation 20110101

Title: Procedure for determination of immunosuppressive drugs in whole blood with liquid chromatography-isotope dilution mass spectrometry.

Journal: Clinical laboratory 20110101

Title: Compassionate use of everolimus in a patient with a neuroendocrine tumor: a case report and discussion of the literature.

Journal: Oncology research 20110101

Title: Two-year outcomes in thoracic transplant recipients after conversion to everolimus with reduced calcineurin inhibitor within a multicenter, open-label, randomized trial.

Journal: Transplantation 20101227

Title: RAD001 shows activity against gastric cancer cells and overcomes 5-FU resistance by downregulating thymidylate synthase.

Journal: Cancer letters 20101218

Title: Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process.

Journal: Cancer research 20101215

Title: Mammalian target of rapamycin: biological function and target for novel anticancer agents.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101215

Title: Outcomes in diabetic and nondiabetic patients treated with everolimus- or paclitaxel-eluting stents: results from the SPIRIT IV clinical trial (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System).

Journal: Journal of the American College of Cardiology 20101214

Title: Drug-eluting versus bare-metal stents in large coronary arteries.

Journal: The New England journal of medicine 20101209

Title: Combinations of mTORC1 inhibitor RAD001 with gemcitabine and paclitaxel for treating non-Hodgkin lymphoma.

Journal: Cancer letters 20101208

Title: Reflex sympathetic dystrophy in patients with metastatic renal cell carcinoma treated with everolimus.

Journal: Investigational new drugs 20101201

Title: TAE226-mediated inhibition of focal adhesion kinase interferes with tumor angiogenesis and vasculogenesis.

Journal: Investigational new drugs 20101201

Title: A phase 2 study of the oral mammalian target of rapamycin inhibitor, everolimus, in patients with recurrent endometrial carcinoma.

Journal: Cancer 20101201

Title: Autosomal dominant polycystic kidney disease and mTOR inhibitors: the narrow road between hope and disappointment.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101201

Title: Third-line sorafenib after sequential therapy with sunitinib and mTOR inhibitors in metastatic renal cell carcinoma.

Journal: European urology 20101201

Title: Phase I study of everolimus plus weekly paclitaxel and trastuzumab in patients with metastatic breast cancer pretreated with trastuzumab.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101201

Title: Determination of cyclosporine, tacrolimus, sirolimus and everolimus by liquid chromatography coupled to electrospray ionization and tandem mass spectrometry: assessment of matrix effects and assay performance.

Journal: Scandinavian journal of clinical and laboratory investigation 20101201

Title: Phase II study of everolimus (RAD001) in previously treated small cell lung cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20101201

Title: The Kounis syndrome in everolimus-eluting stents and paclitaxel-eluting stents.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101201

Title: Do mTOR inhibitors still have a future in ADPKD?

Journal: Nature reviews. Nephrology 20101201

Title: Recurrent stent fracture: first reported image of everolimus-eluting stent fracture leading to recurrent restenosis in cardiac allograft vasculopathy.

Journal: The Journal of invasive cardiology 20101201

Title: Long-term outcome of very early cyclosporine minimization and de novo everolimus therapy in kidney transplant recipients: a pharmacokinetic guided approach.

Journal: Transplantation proceedings 20101201

Title: More than 4 years of progression-free survival in a patient with metastatic renal cell carcinoma treated sequentially with sunitinib, everolimus, sorafenib, and temsirolimus.

Journal: Anticancer research 20101201

Title: Clinical follow-up 3 years after everolimus- and paclitaxel-eluting stents: a pooled analysis from the SPIRIT II (A Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System in the Treatment of Patients With De Novo Native Coronary Artery Lesions) and SPIRIT III (A Clinical Evaluation of the Investigational Device XIENCE V Everolimus Eluting Coronary Stent System [EECSS] in the Treatment of Subjects With De Novo Native Coronary Artery Lesions) randomized trials.

Journal: JACC. Cardiovascular interventions 20101201

Title: Comparison of everolimus-eluting and paclitaxel-eluting coronary stents in patients undergoing multilesion and multivessel intervention: the SPIRIT III (A Clinical Evaluation of the Investigational Device XIENCE V Everolimus Eluting Coronary Stent System [EECSS] in the Treatment of Subjects With De Novo Native Coronary Artery Lesions) and SPIRIT IV (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System in the Treatment of Subjects With De Novo Native Coronary Artery Lesions) randomize

Journal: JACC. Cardiovascular interventions 20101201

Title: Dedicated everolimus-eluting side branch access system: XIENCE SBA.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101201

Title: Side branch occlusion with everolimus-eluting and paclitaxel-eluting stents: three-year results from the SPIRIT III randomised trial.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101201

Title: Intracoronary optical coherence tomography and histology at 1 month and 2, 3, and 4 years after implantation of everolimus-eluting bioresorbable vascular scaffolds in a porcine coronary artery model: an attempt to decipher the human optical coherence tomography images in the ABSORB trial.

Journal: Circulation 20101130

Title: Evaluation of the second generation of a bioresorbable everolimus drug-eluting vascular scaffold for treatment of de novo coronary artery stenosis: six-month clinical and imaging outcomes.

Journal: Circulation 20101130

Title: Bevacizumab and everolimus in renal cancer: a rational way forward.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101120

Title: Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis.

Journal: The New England journal of medicine 20101104

Title: Efficacy and safety of de novo or early everolimus with low cyclosporine in deceased-donor kidney transplant recipients at specified risk of delayed graft function: 12-month results of a randomized, multicenter trial.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20101101

Title: Evaluation of the effects of everolimus-eluting and paclitaxel-eluting stents on target lesions with jailed side branches: 2-year results from the SPIRIT III randomized trial.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101

Title: Efficacy of everolimus eluting stent implantation in patients with calcified coronary culprit lesions: two-year angiographic and three-year clinical results from the SPIRIT II study.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101

Title: Maintenance immunosuppressive therapy with everolimus preserves humoral immune responses.

Journal: Kidney international 20101101

Title: Lipids and renal cystic disease.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101101

Title: Maintenance and consolidation strategies in non-Hodgkin's lymphoma: A review of the data.

Journal: Current oncology reports 20101101

Title: Phase I study of the oral mammalian target of rapamycin inhibitor everolimus (RAD001) in Japanese patients with relapsed or refractory non-Hodgkin lymphoma.

Journal: International journal of hematology 20101101

Title: Warning: this report does not address heavily calcified coronary arteries.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101

Title: More openness and a little less strut: two good ideas for stents and the people who implant them.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101

Title: Strut tissue coverage and endothelial cell coverage: a comparison between bare metal stent platforms and platinum chromium stents with and without everolimus-eluting coating.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101101

Title: A comparison of the conformability of everolimus-eluting bioresorbable vascular scaffolds to metal platform coronary stents.

Journal: JACC. Cardiovascular interventions 20101101

Title: In vivo assessment of local intravascular hemodynamics and arterial morphology to investigate vascular outcomes: a growing field coming of age.

Journal: JACC. Cardiovascular interventions 20101101

Title: Low-dose calcineurin inhibitor regimen combined with mammalian target of rapamycin inhibitors preserves kidney functions in renal transplant recipients without allograft nephropathy.

Journal: Transplantation proceedings 20101101

Title: Malignancies after heart transplantation: incidence, risk factors, and effects of calcineurin inhibitor withdrawal.

Journal: Transplantation proceedings 20101101

Title: Common occurrence of everolimus-associated aphthous stomatitis in Japanese heart transplant recipients.

Journal: Transplantation proceedings 20101101

Title: Recurrent non-melanoma skin cancer: remission of field cancerization after conversion from calcineurin inhibitor- to proliferation signal inhibitor-based immunosuppression in a cardiac transplant recipient.

Journal: Transplantation proceedings 20101101

Title: Impact of mammalian target of rapamycin inhibition on autosomal-dominant polycystic kidney disease.

Journal: Transplantation proceedings 20101101

Title: The therapy of kidney cancer with biomolecular drugs.

Journal: Cancer treatment reviews 20101101

Title: Biological targeted therapies in patients with advanced enteropancreatic neuroendocrine carcinomas.

Journal: Cancer treatment reviews 20101101

Title: mTOR inhibition by everolimus counteracts VEGF induction by sunitinib and improves anti-tumor activity against gastric cancer in vivo.

Journal: Cancer letters 20101028

Title: Early withdrawal of calcineurin inhibitors and everolimus monotherapy in de novo liver transplant recipients preserves renal function.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101001

Title: A phase I-II study of everolimus (RAD001) in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20101001

Title: De novo therapy with everolimus, low-dose ciclosporine A, basiliximab and steroid elimination in pediatric kidney transplantation.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101001

Title: 18F-FLT PET as a surrogate marker of drug efficacy during mTOR inhibition by everolimus in a preclinical cisplatin-resistant ovarian tumor model.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20101001

Title: Phase II trial of gefitinib and everolimus in advanced non-small cell lung cancer.

Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20101001

Title: Everolimus: a proliferation signal inhibitor with clinical applications in organ transplantation, oncology, and cardiology.

Journal: Pharmacotherapy 20101001

Title: Does early (CNI) conversion lead to eternal (renal) salvation?

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101001

Title: Current status of the Xience V® everolimus-eluting coronary stent system.

Journal: Expert review of cardiovascular therapy 20101001

Title: Late conversion to mammalian target of rapamycin inhibitor/proliferation signal inhibitors in kidney transplant patients: clinical experience in the last 5 years.

Journal: Transplantation proceedings 20101001

Title: Proliferation signal inhibitors in heart transplantation: a 5-year experience.

Journal: Transplantation proceedings 20101001

Title: Temporal trends in the use of proliferation signal inhibitors in maintenance heart transplantation: a Spanish multicenter study.

Journal: Transplantation proceedings 20101001

Title: Comparative analysis of adverse events requiring suspension of mTOR inhibitors: everolimus versus sirolimus.

Journal: Transplantation proceedings 20101001

Title: Pneumonitis associated with mammalian target of rapamycin inhibitors in renal transplant recipients: a single-center experience.

Journal: Transplantation proceedings 20101001

Title: Everolimus for the second-line treatment of advanced and/or metastatic renal cell cancer: a critique of the submission from Novartis.

Journal: Health technology assessment (Winchester, England) 20101001

Title: Prolonging hormone sensitivity in prostate cancer xenografts through dual inhibition of AR and mTOR.

Journal: British journal of cancer 20100928

Title: [Everolimus-associated pneumonitis in adult liver transplant recipient].

Journal: Medicina clinica 20100918

Title: Phase 3 trial of everolimus for metastatic renal cell carcinoma : final results and analysis of prognostic factors.

Journal: Cancer 20100915

Title: Spontaneous pyopneumothorax in patients treated with mTOR inhibitors for subpleural pulmonary metastases.

Journal: Medical oncology (Northwood, London, England) 20100901

Title: Targeted agents in metastatic Xp11 translocation/TFE3 gene fusion renal cell carcinoma (RCC): a report from the Juvenile RCC Network.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20100901

Title: Combination of clopidogrel and everolimus dramatically reduced the development of transplant arteriosclerosis in murine aortic allografts.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100901

Title: Phosphorylated mTOR expression is associated with poor prognosis for patients with esophageal squamous cell carcinoma.

Journal: Annals of surgical oncology 20100901

Title: Compensatory activation of Akt in response to mTOR and Raf inhibitors - a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease.

Journal: Cancer letters 20100901

Title: Everolimus as a new potential antiproliferative agent in aggressive human bronchial carcinoids.

Journal: Endocrine-related cancer 20100901

Title: Bevacizumab and everolimus in the treatment of patients with metastatic melanoma: a phase 2 trial of the Sarah Cannon Oncology Research Consortium.

Journal: Cancer 20100901

Title: Everolimus: efficacy and safety in cardiac transplantation.

Journal: Expert opinion on drug safety 20100901

Title: Autophagy induction with RAD001 enhances chemosensitivity and radiosensitivity through Met inhibition in papillary thyroid cancer.

Journal: Molecular cancer research : MCR 20100901

Title: [Second line AUO study AB35/09 of metastasized urothelial cell carcinoma].

Journal: Der Urologe. Ausg. A 20100901

Title: Everolimus-eluting stents: insights from the SPIRIT IV and COMPARE trials.

Journal: Expert review of cardiovascular therapy 20100901

Title: Percutaneous coronary intervention for small-vessel coronary disease: highlight on the everolimus-eluting stent.

Journal: Expert review of cardiovascular therapy 20100901

Title: Timing of conversion to mammalian target of rapamycin inhibitors is crucial in liver transplant recipients with impaired renal function at transplantation.

Journal: Transplantation proceedings 20100901

Title: American Society of Clinical Oncology 2010: report of selected studies from the CNS tumors section.

Journal: Expert review of anticancer therapy 20100901

Title: Comparison of everolimus-eluting and paclitaxel-eluting coronary stents in patients with two treated vessels: 2-year results from the SPIRIT III randomised trial.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100901

Title: Three-year results of clinical follow-up after a bioresorbable everolimus-eluting scaffold in patients with de novo coronary artery disease: the ABSORB trial.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100901

Title: Vascular response to a third generation everolimus-eluting stent.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100901

Title: Murine cytomegalovirus infection leads to increased levels of transplant arteriosclerosis in a murine aortic allograft model.

Journal: Transplantation 20100827

Title: Everolimus in patients with autosomal dominant polycystic kidney disease.

Journal: The New England journal of medicine 20100826

Title: mTOR inhibitors in polycystic kidney disease.

Journal: The New England journal of medicine 20100826

Title: Dual inhibition of EGFR and mTOR pathways in small cell lung cancer.

Journal: British journal of cancer 20100824

Title: Phase 1 and pharmacokinetic study of everolimus, a mammalian target of rapamycin inhibitor, in combination with docetaxel for recurrent/refractory nonsmall cell lung cancer.

Journal: Cancer 20100815

Title: Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer.

Journal: Cancer research 20100815

Title: Comparison of everolimus- versus paclitaxel-eluting stents implanted in patients with diabetes mellitus as evaluated by three-dimensional intravascular ultrasound analysis.

Journal: The American journal of cardiology 20100815

Title: Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus.

Journal: The Journal of clinical investigation 20100802

Title: PIK3CA and KRAS mutations predict for response to everolimus therapy: now that's RAD001.

Journal: The Journal of clinical investigation 20100802

Title: The activity of mTOR inhibitor RAD001 (everolimus) in nasopharyngeal carcinoma and cisplatin-resistant cell lines.

Journal: Investigational new drugs 20100801

Title: Effect of everolimus on skin cancers in calcineurin inhihitor-treated heart transplant recipients.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100801

Title: Noninfectious pneumonitis after everolimus therapy for advanced renal cell carcinoma.

Journal: American journal of respiratory and critical care medicine 20100801

Title: Surface characterization of poly(lactic acid)/everolimus and poly(ethylene vinyl alcohol)/everolimus stents.

Journal: Drug delivery 20100801

Title: Inhibition of mTORC1 by RAD001 (everolimus) potentiates the effects of 1,25-dihydroxyvitamin D(3) to induce growth arrest and differentiation of AML cells in vitro and in vivo.

Journal: Experimental hematology 20100801

Title: Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis.

Journal: Arthritis and rheumatism 20100801

Title: Liquid chromatography-tandem mass spectrometry outperforms fluorescence polarization immunoassay in monitoring everolimus therapy in renal transplantation.

Journal: Therapeutic drug monitoring 20100801

Title: The application of the National Institute of Clinical Excellence guidelines for treatment of metastatic renal cell carcinoma in the United Kingdom: friend or foe?

Journal: BJU international 20100801

Title: In vitro effects of everolimus and intravenous immunoglobulin on cell proliferation and apoptosis induction in the mixed lymphocyte reaction.

Journal: Transplant immunology 20100801

Title: The combination of multiple receptor tyrosine kinase inhibitor and mammalian target of rapamycin inhibitor overcomes erlotinib resistance in lung cancer cell lines through c-Met inhibition.

Journal: Molecular cancer research : MCR 20100801

Title: 3-Dimensional optical coherence tomography assessment of jailed side branches by bioresorbable vascular scaffolds: a proposal for classification.

Journal: JACC. Cardiovascular interventions 20100801

Title: Everolimus in renal cell carcinoma.

Journal: Drugs of today (Barcelona, Spain : 1998) 20100801

Title: Enteric-coated mycophenolate sodium versus mycophenolate mofetil maintenance immunosuppression: outcomes analysis of the United Network for Organ Sharing/Organ Procurement and Transplantation Network database.

Journal: Transplantation 20100715

Title: Optimal everolimus concentration is associated with risk reduction for acute rejection in de novo renal transplant recipients.

Journal: Transplantation 20100715

Title: Comparison of zotarolimus-eluting and everolimus-eluting coronary stents.

Journal: The New England journal of medicine 20100708

Title: Inhibition of MEK/ERK signaling induces apoptosis of acute myelogenous leukemia cells via inhibition of eukaryotic initiation factor 4E-binding protein 1 and down-regulation of Mcl-1.

Journal: Apoptosis : an international journal on programmed cell death 20100701

Title: Inhibition of mTORC1 signaling reduces tumor growth but does not prevent cancer progression in a mouse model of thyroid cancer.

Journal: Carcinogenesis 20100701

Title: New developments in targeted therapy for soft tissue sarcoma.

Journal: Current oncology reports 20100701

Title: Sirolimus and everolimus reduce albumin endocytosis in proximal tubule cells via an angiotensin II-dependent pathway.

Journal: Transplant immunology 20100701

Title: New drugs in neuroendocrine tumors: rising of new therapeutic philosophies?

Journal: Current opinion in oncology 20100701

Title: Gene expression profiling of response to mTOR inhibitor everolimus in pre-operatively treated post-menopausal women with oestrogen receptor-positive breast cancer.

Journal: Breast cancer research and treatment 20100701

Title: Which DES for diabetics? Round 1: A draw. Round 2: Everolimus leading?

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701

Title: An everolimus-eluting stent versus a paclitaxel-eluting stent in small vessel coronary artery disease: a pooled analysis from the SPIRIT II and SPIRIT III trials.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701

Title: Another small step for small vessels.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701

Title: SPIRIT III JAPAN versus SPIRIT III USA: a comparative intravascular ultrasound analysis of the everolimus-eluting stent.

Journal: The American journal of cardiology 20100701

Title: Clinical recommendations for the use of everolimus in heart transplantation.

Journal: Transplantation reviews (Orlando, Fla.) 20100701

Title: [Current impact of natural products in the discovery of anticancer drugs].

Journal: Annales pharmaceutiques francaises 20100701

Title: Correlation between circulating endothelial progenitor cell function and allograft rejection in heart transplant patients.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100601

Title: Proximal protection in recanalization of totally occluded saphenous vein grafts in acute coronary syndrome.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601

Title: Update on systemic therapies of metastatic renal cell carcinoma.

Journal: World journal of urology 20100601

Title: Reversible severe synovitis associated with everolimus.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20100601

Title: Substitution of corticosteroid with everolimus after lung transplantation: a pediatric case report.

Journal: Pharmacy world & science : PWS 20100601

Title: Benefit of early conversion from CNI-based to everolimus-based immunosuppression in heart transplantation.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20100601

Title: Emergent toxicities associated with the use of mTOR inhibitors in patients with advanced renal carcinoma.

Journal: Anti-cancer drugs 20100601

Title: Effects of vatalanib on tumor growth can be potentiated by mTOR blockade in vivo.

Journal: Cancer biology & therapy 20100601

Title: Everolimus plus reduced-exposure CsA versus mycophenolic acid plus standard-exposure CsA in renal-transplant recipients.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100601

Title: Regulation of insulin-like growth factor-mammalian target of rapamycin signaling by microRNA in childhood adrenocortical tumors.

Journal: Cancer research 20100601

Title: Five-year long-term clinical follow-up of the XIENCE V everolimus eluting coronary stent system in the treatment of patients with de novo coronary artery lesions: the SPIRIT FIRST trial.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601

Title: Long-term follow-up of the First In Man experience with everolimus-eluting stents.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601

Title: Procedure-related myonecrosis after bare and drug-eluting stent implantation.

Journal: Asian cardiovascular & thoracic annals 20100601

Title: [mTOR inhibitors].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20100601

Title: Relationship between everolimus blood concentration assessed using the Innofluor Certican Fluorescence Polarization Immunoassay and the Architect i System sirolimus chemiluminescent microparticle immunoassay.

Journal: Transplantation proceedings 20100601

Title: Initial experience with an everolimus-eluting, second-generation drug-eluting stent for treatment of intracranial atherosclerosis.

Journal: Journal of neurointerventional surgery 20100601

Title: Everolimus-eluting versus paclitaxel-eluting stents in coronary artery disease.

Journal: The New England journal of medicine 20100506

Title: Second-generation drug-eluting coronary stents.

Journal: The New England journal of medicine 20100506

Title: Everolimus and pazopanib: two new drugs for renal cell cancer.

Journal: The Medical letter on drugs and therapeutics 20100503

Title: mTOR inhibitor RAD001 (Everolimus) enhances the effects of imatinib in chronic myeloid leukemia by raising the nuclear expression of c-ABL protein.

Journal: Leukemia research 20100501

Title: Sirolimus and everolimus clearance in maintenance kidney and liver transplant recipients: diagnostic efficiency of the concentration/dose ratio for the prediction of trough steady-state concentrations.

Journal: Upsala journal of medical sciences 20100501

Title: Effects of the novel protein kinase C inhibitor AEB071 (Sotrastaurin) on rat cardiac allograft survival using single agent treatment or combination therapy with cyclosporine, everolimus or FTY720.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100501

Title: Identification of functional FKB protein in Echinococcus granulosus: its involvement in the protoscolicidal action of rapamycin derivates and in calcium homeostasis.

Journal: International journal for parasitology 20100501

Title: IVUS radiofrequency analysis in the evaluation of the polymeric struts of the bioabsorbable everolimus-eluting device during the bioabsorption process.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100501

Title: Randomized comparison of everolimus- and paclitaxel-eluting stents: pooled analysis of the 2-year clinical follow-up from the SPIRIT II and III trials.

Journal: European heart journal 20100501

Title: Therapies for the medical management of persistent hypoglycaemia in two cases of inoperable malignant insulinoma.

Journal: European journal of endocrinology 20100501

Title: The treatment of recurrent/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL) with everolimus results in clinical responses and mobilization of CLL cells into the circulation.

Journal: Cancer 20100501

Title: A Phase II trial of the oral mTOR inhibitor everolimus in relapsed Hodgkin lymphoma.

Journal: American journal of hematology 20100501

Title: Personalized molecular targeted therapy in advanced, recurrent hepatocellular carcinoma after liver transplantation: a proof of principle.

Journal: Journal of hepatology 20100501

Title: How to interpret phase II data for everolimus plus bevacizumab in renal cell carcinoma.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100501

Title: Phase II trial of bevacizumab and everolimus in patients with advanced renal cell carcinoma.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100501

Title: Novel immunosuppressive agents in kidney transplantation.

Journal: Clinical nephrology 20100501

Title: Vascular response to overlapping everolimus-eluting stents. - Comparison with paclitaxel-eluting stents -.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20100501

Title: Everolimus in relapsed Hodgkin's lymphoma: something exciting or a case of caveat mTOR?

Journal: American journal of hematology 20100501

Title: [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma].

Journal: Aktuelle Urologie 20100501

Title: [Gingival hyperplasia secondary to everolimus therapy].

Journal: Actas dermo-sifiliograficas 20100501

Title: De novo everolimus-based therapy in renal transplant recipients: effect on proteinuria and renal prognosis.

Journal: Transplantation proceedings 20100501

Title: Once-a-day administration of everolimus, cyclosporine, and steroid after renal transplantation: a review of the rationale.

Journal: Transplantation proceedings 20100501

Title: Once daily everolimus is safe and effective in de novo renal transplant recipients: six-month results of a pilot study.

Journal: Transplantation proceedings 20100501

Title: Conversion of stable kidney transplant recipients from a twice-daily to once-daily everolimus regimen.

Journal: Transplantation proceedings 20100501

Title: Lower homocysteine levels in renal transplant recipients treated with everolimus: a possible link with a decreased cardiovascular risk?

Journal: Transplantation proceedings 20100501

Title: A randomised comparison between everolimus-eluting stent and sirolimus-eluting stent in chronic coronary total occlusions. Rationale and design of the CIBELES (non-acute Coronary occlusion treated by EveroLimus-Eluting Stent) trial.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100501

Title: Present state of target therapy for disseminated renal cell carcinoma.

Journal: Immunotherapy 20100501

Title: Interaction between everolimus and tacrolimus in renal transplant recipients: a pharmacokinetic controlled trial.

Journal: Transplantation 20100427

Title: Everolimus with reduced calcineurin inhibitor in thoracic transplant recipients with renal dysfunction: a multicenter, randomized trial.

Journal: Transplantation 20100415

Title: Sensitive quantification of sirolimus and everolimus by LC-MS/MS with online sample cleanup.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100415

Title: Multicenter phase II study of everolimus in patients with previously treated metastatic gastric cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100410

Title: Everolimus-eluting versus paclitaxel-eluting stents.

Journal: Lancet (London, England) 20100403

Title: Everolimus-eluting versus paclitaxel-eluting stents.

Journal: Lancet (London, England) 20100403

Title: Impact of Cyclin B2 and Cell division cycle 2 on tubular hyperplasia in progressive chronic renal failure rats.

Journal: American journal of physiology. Renal physiology 20100401

Title: A clinical and angiographic study of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with multivessel coronary artery disease. Study design and rationale of the EXECUTIVE trial.

Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20100401

Title: RAD001 offers a therapeutic intervention through inhibition of mTOR as a potential strategy for esophageal cancer.

Journal: Oncology reports 20100401

Title: Palliative chemotherapy for pancreatic malignancies.

Journal: The Surgical clinics of North America 20100401

Title: Monitoring in vivo absorption of a drug-eluting bioabsorbable stent with intravascular ultrasound-derived parameters a feasibility study.

Journal: JACC. Cardiovascular interventions 20100401

Title: Can cyclosporine blood level be reduced to half after heart transplantation?

Journal: Transplantation proceedings 20100401

Title: The survival of heart transplant recipients using cyclosporine and everolimus is not inferior to that using cyclosporine and mycophenolate.

Journal: Transplantation proceedings 20100401

Title: [Everolimus (RAD001/Afinitor) in the treatment of metastatic cell carcinoma].

Journal: Revue medicale de Liege 20100401

Title: In vivo evaluation of stent strut distribution patterns in the bioabsorbable everolimus-eluting device: an OCT ad hoc analysis of the revision 1.0 and revision 1.1 stent design in the ABSORB clinical trial.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100401

Title: Lesion complexity determines arterial drug distribution after local drug delivery.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20100319

Title: Immunosuppressant neurotoxicity in rat brain models: oxidative stress and cellular metabolism.

Journal: Chemical research in toxicology 20100315

Title: Phase II trial of the oral mammalian target of rapamycin inhibitor everolimus in relapsed or refractory Waldenstrom macroglobulinemia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100310

Title: Neuroendocrine tumors of the pancreas: what's new. Highlights from the '2010 ASCO Gastrointestinal Cancers Symposium'. Orlando, FL, USA. January 22-24, 2010.

Journal: JOP : Journal of the pancreas 20100305

Title: Comparative pharmacokinetics of RAD001 (everolimus) in normal and tumor-bearing rodents.

Journal: Cancer chemotherapy and pharmacology 20100301

Title: Everolimus.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100301

Title: [Recent progress in the molecular-targeting treatment of neuroendocrine tumors].

Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20100301

Title: Everolimus (RAD001) in the treatment of advanced renal cell carcinoma: a review.

Journal: The oncologist 20100301

Title: Rescue immunosuppression with mammalian target of rapamycin inhibitor drugs in liver transplantation.

Journal: Transplantation proceedings 20100301

Title: [Vessel response evaluation by optical coherence tomography after drug-eluting stent implantation in the left main coronary artery].

Journal: Giornale italiano di cardiologia (2006) 20100301

Title: StatBite: FDA oncology drug product approvals in 2009.

Journal: Journal of the National Cancer Institute 20100224

Title: Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy.

Journal: Cancer research 20100215

Title: The rapamycin-derivative RAD001 (everolimus) inhibits cell viability and interacts with the Akt-mTOR-p70S6K pathway in human medullary thyroid carcinoma cells.

Journal: Molecular and cellular endocrinology 20100205

Title: Cost-effectiveness of immunosuppressive regimens in renal transplant recipients in Germany: a model approach.

Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20100201

Title: Lower incidence of cytomegalovirus infection with everolimus versus mycophenolate mofetil in de novo cardiac transplant recipients: a randomized, multicenter study.

Journal: Transplant infectious disease : an official journal of the Transplantation Society 20100201

Title: Clinical and angiographic outcomes with an everolimus-eluting stent in large coronary arteries: the SPIRIT III 4.0 mm registry.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100201

Title: Potential role of everolimus in inducing cholestasis.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20100201

Title: Effect of everolimus on cell viability in nonfunctioning pituitary adenomas.

Journal: The Journal of clinical endocrinology and metabolism 20100201

Title: Ultra fast liquid chromatography-tandem mass spectrometry routine method for simultaneous determination of cyclosporin A, tacrolimus, sirolimus, and everolimus in whole blood using deuterated internal standards for cyclosporin A and everolimus.

Journal: Therapeutic drug monitoring 20100201

Title: RAD 001 (everolimus) prevents mTOR and Akt late re-activation in response to imatinib in chronic myeloid leukemia.

Journal: Journal of cellular biochemistry 20100201

Title: Experience with everolimus (RAD001), an oral mammalian target of rapamycin inhibitor, in patients with systemic mastocytosis.

Journal: Leukemia & lymphoma 20100201

Title: Pharmacokinetic sub-study in the SPIRIT III Randomized and Controlled Trial of XIENCE V everolimus eluting coronary stent system.

Journal: Journal of interventional cardiology 20100201

Title: A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer.

Journal: Molecular endocrinology (Baltimore, Md.) 20100201

Title: New Drugs2010, PART 1.

Journal: Nursing 20100201

Title: Surgical biology for the clinician: vascular effects of immunosuppression.

Journal: Canadian journal of surgery. Journal canadien de chirurgie 20100201

Title: Augmentation of autophagy by mTOR-inhibition in myocardial infarction: When size matters.

Journal: Autophagy 20100201

Title: Dependence on phosphoinositide 3-kinase and RAS-RAF pathways drive the activity of RAF265, a novel RAF/VEGFR2 inhibitor, and RAD001 (Everolimus) in combination.

Journal: Molecular cancer therapeutics 20100201

Title: Diffuse alveolar hemorrhage induced by everolimus.

Journal: Chest 20100201

Title: Sotrastaurin and everolimus pharmacokinetics after single-dose coadministration.

Journal: International journal of clinical pharmacology and therapeutics 20100201

Title: A pooled gender based analysis comparing the XIENCE V(R) everolimus-eluting stent and the TAXUS paclitaxel-eluting stent in male and female patients with coronary artery disease, results of the SPIRIT II and SPIRIT III studies: two-year analysis.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100201

Title: Cyclosporine lowering with everolimus or mycophenolate to preserve renal function in heart recipients: a randomized study.

Journal: Transplantation 20100127

Title: Second-generation everolimus-eluting and paclitaxel-eluting stents in real-life practice (COMPARE): a randomised trial.

Journal: Lancet (London, England) 20100116

Title: Everolimus or paclitaxel stents in real life: go COMPARE.

Journal: Lancet (London, England) 20100116

Title: Everolimus-induced pneumonitis: report of the first case in a liver transplant recipient and review of treatment options.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100101

Title: Rapamycin promotes arterial thrombosis in vivo: implications for everolimus and zotarolimus eluting stents.

Journal: European heart journal 20100101

Title: mTOR inhibitor everolimus ameliorates progressive tubular dysfunction in chronic renal failure rats.

Journal: Biochemical pharmacology 20100101

Title: Phase I clinical and pharmacokinetic study of RAD001 (everolimus) administered daily to Japanese patients with advanced solid tumors.

Journal: Japanese journal of clinical oncology 20100101

Title: Daily oral everolimus activity in patients with metastatic pancreatic neuroendocrine tumors after failure of cytotoxic chemotherapy: a phase II trial.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100101

Title: Recent progress in percutaneous coronary intervention: evolution of the drug-eluting stents, focus on the XIENCE V drug-eluting stent.

Journal: Coronary artery disease 20100101

Title: Reduction of cyclosporine following the introduction of everolimus in maintenance heart transplant recipients: a pilot study.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100101

Title: Persistent effects of everolimus on strength of experimental wounds in intestine and fascia.

Journal: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20100101

Title: Progress in the management of advanced renal cell carcinoma (RCC).

Journal: Aktuelle Urologie 20100101

Title: Long-term laryngeal allograft survival using low-dose everolimus.

Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20100101

Title: Lingual angioedema associated with everolimus.

Journal: Acta oncologica (Stockholm, Sweden) 20100101

Title: [Current aspects of second-line and sequence therapy of metastatic renal cell carcinoma].

Journal: Onkologie 20100101

Title: [Outlook: Future therapy of renal cell carcinoma].

Journal: Onkologie 20100101

Title: Everolimus versus azathioprine in a cyclosporine and ketoconazole-based immunosuppressive therapy in kidney transplant: 3-year follow-up of an open-label, prospective, cohort, comparative clinical trial.

Journal: Transplantation proceedings 20100101

Title: Results of the conversion to everolimus in renal transplant recipients with posttransplantation malignancies.

Journal: Transplantation proceedings 20100101

Title: South American Heart Transplantation Registry of patients receiving everolimus in their immunosuppressive regimens.

Journal: Transplantation proceedings 20100101

Title: Everolimus in lung transplantation in Chile.

Journal: Transplantation proceedings 20100101

Title: New therapeutic strategies for renal cell carcinoma.

Journal: Urologic nursing 20100101

Title: [Toxic effect of immunosuppression agent Everolimus on insuloma cells and pancreatic islets of SD rat].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100101

Title: A therapeutic exploratory study to determine the efficacy and safety of calcineurin-inhibitor-free de-novo immunosuppression after liver transplantation: CILT.

Journal: BMC surgery 20100101

Title: [Renal cell carcinoma management and therapies in 2010].

Journal: Bulletin du cancer 20100101

Title: [mTOR inhibitors: temsirolimus and everolimus in the treatment of renal cell carcinoma].

Journal: Bulletin du cancer 20100101

Title: [Advanced renal carcinomas with special situations. How to treat them?].

Journal: Bulletin du cancer 20100101

Title: Different immunosuppressive combinations on T-cell regulation in renal transplant recipients.

Journal: American journal of nephrology 20100101

Title: Rationale and design of a randomized clinical comparison of everolimus-eluting (Xience v/Promus) and sirolimus-eluting (cypher select+) coronary stents in unselected patients with coronary heart disease.

Journal: Cardiology 20100101

Title: Inhibition of the mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: results of two phase II studies.

Journal: BMC cancer 20100101

Title: [Interstitial pneumonitis from everolimus].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20100101

Title: Severe stomatitis complicating immune-suppressive switch after cardiac transplantation.

Journal: Acta chirurgica Belgica 20100101

Title: Calcineurin inhibitors in renal transplantation still needed but in reduced doses: a review.

Journal: Transplantation proceedings 20100101

Title: Rationale and design of EXPLORE: a randomized, prospective, multicenter trial investigating the impact of recanalization of a chronic total occlusion on left ventricular function in patients after primary percutaneous coronary intervention for acute ST-elevation myocardial infarction.

Journal: Trials 20100101

Title: Activated mammalian target of rapamycin is a potential therapeutic target in gastric cancer.

Journal: BMC cancer 20100101

Title: Targeted therapy in lymphoma.

Journal: Journal of hematology & oncology 20100101

Title: Primary PCI for acute anterior wall MI with pulmonary edema and left anterior descending artery ostial stenosis.

Journal: Indian heart journal 20100101

Title: Preclinical evaluation of KIT/PDGFRA and mTOR inhibitors in gastrointestinal stromal tumors using small animal FDG PET.

Journal: Journal of experimental & clinical cancer research : CR 20100101

Title: Clinical studies with sirolimus, zotarolimus, everolimus, and biolimus A9 drug-eluting stent systems.

Journal: Current pharmaceutical design 20100101

Title: Is it possible to optimize the use of targeted therapies in the treatment of renal cell carcinoma?

Journal: Tumori 20100101

Title: Perspectives in the development of novel treatment approaches.

Journal: Tumori 20100101

Title: Beneficial effects of Mammalian target of rapamycin inhibition on left ventricular remodeling after myocardial infarction.

Journal: Journal of the American College of Cardiology 20091215

Title: Assimilating the current clinical data of fully bioabsorbable stents.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215

Title: Everolimus-eluting bioabsorbable stent--Abbot Vascular programme.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215

Title: Quality of life in patients with metastatic renal cell carcinoma: the importance of patient-reported outcomes.

Journal: Cancer treatment reviews 20091201

Title: The carina angle-new geometrical parameter associated with periprocedural side branch compromise and the long-term results in coronary bifurcation lesions with main vessel stenting only.

Journal: Journal of interventional cardiology 20091201

Title: Exploring mammalian target of rapamycin (mTOR) inhibition for treatment of mantle cell lymphoma and other hematologic malignancies.

Journal: Leukemia & lymphoma 20091201

Title: Pulse mTOR inhibitor treatment effectively controls cyst growth but leads to severe parenchymal and glomerular hypertrophy in rat polycystic kidney disease.

Journal: American journal of physiology. Renal physiology 20091201

Title: Effect of itraconazole on the pharmacokinetics of everolimus administered by different routes in rats.

Journal: Biopharmaceutics & drug disposition 20091201

Title: Emerging treatment combinations: integrating therapy into clinical practice.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20091201

Title: Improvement of renal function after the switch from a calcineurin inhibitor to everolimus in liver transplant recipients with chronic renal dysfunction.

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091201

Title: Metastatic renal cell carcinoma: current standards of care.

Journal: Clinical journal of oncology nursing 20091201

Title: Management of mTOR inhibitor side effects.

Journal: Clinical journal of oncology nursing 20091201

Title: The role of mTOR in bladder cancer.

Journal: Cancer biology & therapy 20091201

Title: Clinical and angiographic comparison of everolimus-eluting and paclitaxel-eluting stents in small coronary arteries: a post hoc analysis of the SPIRIT III randomized trial.

Journal: American heart journal 20091201

Title: Preprocedural inflammation does not affect neointimal hyperplasia following everolimus-eluting stent implantation.

Journal: The Journal of invasive cardiology 20091201

Title: Renal function outcomes in kidney transplant recipients after conversion to everolimus-based immunosuppression regimen with CNI reduction or elimination.

Journal: Transplantation proceedings 20091201

Title: Immunosuppression using the mammalian target of rapamycin (mTOR) inhibitor everolimus: pilot study shows significant cognitive and affective improvement.

Journal: Transplantation proceedings 20091201

Title: Inhibition of mammalian target of rapamycin as a therapeutic strategy in the management of bladder cancer.

Journal: Cancer biology & therapy 20091201

Title: [Benefits of proliferation signal inhibitors beyond immunosuppression. Vascular protection and experience in heart transplantation].

Journal: Nephrologie & therapeutique 20091201

Title: [Proliferation signal inhibitors: what therapeutic protocols are followed in 2009?].

Journal: Nephrologie & therapeutique 20091201

Title: [Replacing calcineurin inhibitors with proliferation signal inhibitors after kidney transplantation: indications, results, and disadvantages].

Journal: Nephrologie & therapeutique 20091201

Title: 3-year clinical follow-up of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with de novo coronary artery lesions: the SPIRIT II trial (Clinical Evaluation of the Xience V Everolimus Eluting Coronary Stent System in the Treatment of Patients with de novo Native Coronary Artery Lesions).

Journal: JACC. Cardiovascular interventions 20091201

Title: Clinical outcomes after unrestricted implantation of everolimus-eluting stents.

Journal: JACC. Cardiovascular interventions 20091201

Title: Everolimus with very low-exposure cyclosporine a in de novo kidney transplantation: a multicenter, randomized, controlled trial.

Journal: Transplantation 20091127

Title: The role of mTORC1 pathway in intestinal tumorigenesis.

Journal: Cell cycle (Georgetown, Tex.) 20091115

Title: Therapeutic drug monitoring of everolimus using the dried blood spot method in combination with liquid chromatography-mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20091101

Title: Gender-based evaluation of the XIENCE V everolimus-eluting coronary stent system: clinical and angiographic results from the SPIRIT III randomized trial.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091101

Title: Involvement of mTOR kinase in cytokine-dependent microglial activation and cell proliferation.

Journal: Biochemical pharmacology 20091101

Title: Rapamycin selectively inhibits expression of an inducible keratin (K6a) in human keratinocytes and improves symptoms in pachyonychia congenita patients.

Journal: Journal of dermatological science 20091101

Title: Characterization of pneumonitis in patients with advanced non-small cell lung cancer treated with everolimus (RAD001).

Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20091101

Title: Everolimus but not mycophenolate mofetil therapy is associated with soluble HLA-G expression in heart transplant patients.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20091101

Title: Downregulation of 18F-FDG uptake in PET as an early pharmacodynamic effect in treatment of non-small cell lung cancer with the mTOR inhibitor everolimus.

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20091101

Title: Transplantation: time to rethink immunosuppression by mTOR inhibitors?

Journal: Nature reviews. Nephrology 20091101

Title: Sirolimus: a novel immunosuppressive drug in heart transplantation.

Journal: Recent patents on cardiovascular drug discovery 20091101

Title: [Indications of mTOR inhibitors in liver transplantation].

Journal: Gastroenterologie clinique et biologique 20091101

Title: Everolimus de novo in liver transplantation.

Journal: Gastroenterologie clinique et biologique 20091101

Title: [Antitumoral effect of proliferation signal inhibitors].

Journal: Gastroenterologie clinique et biologique 20091101

Title: How should I treat a complex Post-CABG patient?

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091101

Title: Everolimus: in advanced renal cell carcinoma.

Journal: Drugs 20091022

Title: Gastric cancer: trastuzumab trial results spur search for other targets.

Journal: Journal of the National Cancer Institute 20091007

Title: Inhibition of mammalian target of rapamycin (mTOR) signalling in C2C12 myoblasts prevents myogenic differentiation without affecting the hyperphosphorylation of 4E-BP1.

Journal: Cellular signalling 20091001

Title: Inhibition of mammalian target of rapamycin signaling potentiates the effects of all-trans retinoic acid to induce growth arrest and differentiation of human acute myelogenous leukemia cells.

Journal: International journal of cancer 20091001

Title: Role of the novel mTOR inhibitor RAD001 (everolimus) in anaplastic thyroid cancer.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20091001

Title: Efficacy of everolimus (RAD001) in patients with advanced NSCLC previously treated with chemotherapy alone or with chemotherapy and EGFR inhibitors.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20091001

Title: Randomized, non-inferiority trial of three limus agent-eluting stents with different polymer coatings: the Intracoronary Stenting and Angiographic Results: Test Efficacy of 3 Limus-Eluting Stents (ISAR-TEST-4) Trial.

Journal: European heart journal 20091001

Title: SPIRIT IV trial design: a large-scale randomized comparison of everolimus-eluting stents and paclitaxel-eluting stents in patients with coronary artery disease.

Journal: American heart journal 20091001

Title: Conversion from a calcineurin inhibitor to everolimus therapy in maintenance liver transplant recipients: a prospective, randomized, multicenter trial.

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091001

Title: Randomized phase II study comparing two schedules of everolimus in patients with recurrent/metastatic breast cancer: NCIC Clinical Trials Group IND.163.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090920

Title: Novel and evolving therapies in the treatment of malignant phaeochromocytoma: experience with the mTOR inhibitor everolimus (RAD001).

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090901

Title: Everolimus restores gefitinib sensitivity in resistant non-small cell lung cancer cell lines.

Journal: Biochemical pharmacology 20090901

Title: Mammalian target of rapamycin inhibitors rapamycin and RAD001 (everolimus) induce anti-proliferative effects in GH-secreting pituitary tumor cells in vitro.

Journal: Endocrine-related cancer 20090901

Title: mTOR is a promising therapeutic target both in cisplatin-sensitive and cisplatin-resistant clear cell carcinoma of the ovary.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090901

Title: Proliferation signal inhibitors for the treatment of refractory autoimmune rheumatic diseases: a new therapeutic option.

Journal: Annals of the New York Academy of Sciences 20090901

Title: Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia.

Journal: Blood 20090820

Title: Targeted inhibition of mammalian target of rapamycin for the treatment of advanced renal cell carcinoma.

Journal: Cancer 20090815

Title: Minimization of maintenance immunosuppression early after renal transplantation: an interim analysis.

Journal: Transplantation 20090815

Title: Increased interleukin-10 production without expansion of CD4+CD25+ T-regulatory cells in early stable renal transplant patients on calcineurin inhibitors.

Journal: Transplantation 20090815

Title: Everolimus, a promising medical therapy for coronary heart disease?

Journal: Medical hypotheses 20090801

Title: Rapamycin delays tumor development in murine livers by inhibiting proliferation of hepatocytes with DNA damage.

Journal: Hepatology (Baltimore, Md.) 20090801

Title: Two-year clinical, angiographic, and intravascular ultrasound follow-up of the XIENCE V everolimus-eluting stent in the treatment of patients with de novo native coronary artery lesions: the SPIRIT II trial.

Journal: Circulation. Cardiovascular interventions 20090801

Title: Contrast enhanced sonography shows superior microvascular renal allograft perfusion in patients switched from cyclosporine A to everolimus.

Journal: Transplantation 20090727

Title: Incidence of delayed graft function and wound healing complications after deceased-donor kidney transplantation is not affected by de novo everolimus.

Journal: Transplantation 20090715

Title: Everolimus with reduced cyclosporine versus MMF with standard cyclosporine in de novo heart transplant recipients.

Journal: Transplantation 20090715

Title: The everolimus-eluting stent in real-world patients: 6-month follow-up of the X-SEARCH (Xience V Stent Evaluated at Rotterdam Cardiac Hospital) registry.

Journal: Journal of the American College of Cardiology 20090714

Title: RAD001 (everolimus) inhibits tumour growth in xenograft models of human hepatocellular carcinoma.

Journal: Journal of cellular and molecular medicine 20090701

Title: RAD001 (Everolimus) induces autophagy in acute lymphoblastic leukemia.

Journal: Autophagy 20090701

Title: The impact of everolimus versus mycophenolate on blood and lymphocyte cyclosporine exposure in heart-transplant recipients.

Journal: European journal of clinical pharmacology 20090701

Title: Everolimus.

Journal: Nature reviews. Drug discovery 20090701

Title: New mTOR inhibitor for renal cell cancer.

Journal: Oncology (Williston Park, N.Y.) 20090701

Title: A novel accelerated in vitro release method for biodegradable coating of drug eluting stents: Insight to the drug release mechanisms.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628

Title: Sirolimus and everolimus induce endothelial cellular senescence via sirtuin 1 down-regulation: therapeutic implication of cilostazol after drug-eluting stent implantation.

Journal: Journal of the American College of Cardiology 20090616

Title: FDG uptake is a surrogate marker for defining the optimal biological dose of the mTOR inhibitor everolimus in vivo.

Journal: British journal of cancer 20090602

Title: Combination of immunosuppressive drugs leaves specific 'fingerprint' on gene expression in vitro.

Journal: Immunopharmacology and immunotoxicology 20090601

Title: A phase 2 study with a daily regimen of the oral mTOR inhibitor RAD001 (everolimus) in patients with metastatic clear cell renal cell cancer.

Journal: Cancer 20090601

Title: Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090601

Title: Everolimus (RAD001): an mTOR inhibitor for the treatment of metastatic renal cell carcinoma.

Journal: Expert review of anticancer therapy 20090601

Title: Bioabsorbable coronary stents.

Journal: Circulation. Cardiovascular interventions 20090601

Title: Targeting mTOR in renal cell carcinoma.

Journal: Cancer 20090515

Title: Disposition of everolimus in mdr1a-/1b- mice and after a pre-treatment of lapatinib in Swiss mice.

Journal: Biochemical pharmacology 20090515

Title: Decrease in sirolimus-induced proteinuria after switch to everolimus in a liver transplant recipient with diabetic nephropathy.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20090501

Title: [Targeted therapies and their indications in solid neoplasias].

Journal: La Revue de medecine interne 20090501

Title: Progress in the treatment of neuroendocrine tumors.

Journal: Current oncology reports 20090501

Title: Targeted therapies in metastatic renal cancer in 2009.

Journal: BJU international 20090501

Title: Ultra-performance hydrophilic interaction liquid chromatography/tandem mass spectrometry for the determination of everolimus in mouse plasma.

Journal: Rapid communications in mass spectrometry : RCM 20090501

Title: Efficacy of Xience/promus versus Cypher in rEducing Late Loss after stENTing (EXCELLENT) trial: study design and rationale of a Korean multicenter prospective randomized trial.

Journal: American heart journal 20090501

Title: New oral treatment for kidney cancer approved.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090501

Title: Intravascular ultrasound guidance of multiple drug-eluting stent implantation in lesions associated with coronary aneurysms.

Journal: The Journal of invasive cardiology 20090501

Title: Xience V everolimus-eluting coronary stent.

Journal: Expert review of medical devices 20090501

Title: The applicability of mTOR inhibition in solid tumors.

Journal: Current cancer drug targets 20090501

Title: Prospective clinical trial comparing two immunosuppressive regimens, tacrolimus and mycophenolate mofetil versus everolimus and low-dose cyclosporine, in de novo renal transplant recipients: results at 6 months follow-up.

Journal: Transplantation proceedings 20090501

Title: Cardiovascular risk profile in kidney transplant recipients treated with two immunosuppressive regimens: tacrolimus and mycophenolate mofetil versus everolimus and low-dose cyclosporine.

Journal: Transplantation proceedings 20090501

Title: Immunosuppressive agents and metabolic factors of cardiovascular risk in renal transplant recipients.

Journal: Transplantation proceedings 20090501

Title: Posttransplant proteinuria associated with everolimus.

Journal: Transplantation proceedings 20090501

Title: The impact of everolimus on renal function in maintenance liver transplantation.

Journal: Transplantation proceedings 20090501

Title: Does everolimus associated with a low dose of cyclosporine in long-term cardiac transplant recipients improve renal function? Initial experience.

Journal: Transplantation proceedings 20090501

Title: Incomplete stent apposition and delayed tissue coverage are more frequent in drug-eluting stents implanted during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction than in drug-eluting stents implanted for stable/unstable angina: insights from optical coherence tomography.

Journal: JACC. Cardiovascular interventions 20090501

Title: The pharmacology of mTOR inhibition.

Journal: Science signaling 20090421

Title: Potentiating effects of RAD001 (Everolimus) on vincristine therapy in childhood acute lymphoblastic leukemia.

Journal: Blood 20090402

Title: Everolimus and sirolimus antagonize tacrolimus based calcineurin inhibition via competition for FK-binding protein 12.

Journal: Biochemical pharmacology 20090401

Title: Myeloma cell growth inhibition is augmented by synchronous inhibition of the insulin-like growth factor-1 receptor by NVP-AEW541 and inhibition of mammalian target of rapamycin by Rad001.

Journal: Anti-cancer drugs 20090401

Title: The HER-2 receptor and breast cancer: ten years of targeted anti-HER-2 therapy and personalized medicine.

Journal: The oncologist 20090401

Title: Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition.

Journal: Molecular cancer therapeutics 20090401

Title: Right adrenal metastases of hepatocarcinoma after liver transplantation: case report and literature review.

Journal: Transplantation proceedings 20090401

Title: mTOR in renal cell cancer: modulator of tumor biology and therapeutic target.

Journal: Expert review of molecular diagnostics 20090401

Title: RAD001 (Everolimus) Can prevent tamoxifen-related endometrial and stromal hyperplasia.

Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20090401

Title: A bioabsorbable everolimus-eluting coronary stent system (ABSORB): 2-year outcomes and results from multiple imaging methods.

Journal: Lancet (London, England) 20090314

Title: Nanoscale mechanical measurement determination of the glass transition temperature of poly(lactic acid)/everolimus coated stents in air and dissolution media.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090302

Title: A pilot trial of the mTOR (mammalian target of rapamycin) inhibitor RAD001 in patients with advanced B-CLL.

Journal: Annals of hematology 20090301

Title: A pilot study of everolimus and gefitinib in the treatment of recurrent glioblastoma (GBM).

Journal: Journal of neuro-oncology 20090301

Title: Conversion to everolimus monotherapy in maintenance liver transplantation: feasibility, safety, and impact on renal function.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20090301

Title: Everolimus attenuates neointimal hyperplasia in cultured human saphenous vein grafts.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20090301

Title: mTOR inhibitor RAD001 (everolimus) has antiangiogenic/vascular properties distinct from a VEGFR tyrosine kinase inhibitor.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090301

Title: Recommendations from the Spanish Oncology Genitourinary Group for the treatment of metastatic renal cancer.

Journal: Cancer chemotherapy and pharmacology 20090301

Title: Progression of renal dysfunction in cardiac transplantation after the introduction of everolimus in the immunosuppressive regime.

Journal: Transplantation 20090227

Title: AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090215

Title: Randomized comparison of everolimus-eluting and paclitaxel-eluting stents: two-year clinical follow-up from the Clinical Evaluation of the Xience V Everolimus Eluting Coronary Stent System in the Treatment of Patients with de novo Native Coronary Artery Lesions (SPIRIT) III trial.

Journal: Circulation 20090210

Title: Everolimus inhibits monocyte/macrophage migration in vitro and their accumulation in carotid lesions of cholesterol-fed rabbits.

Journal: The Journal of pharmacology and experimental therapeutics 20090201

Title: Robust, high-throughput LC-MS/MS method for therapeutic drug monitoring of cyclosporine, tacrolimus, everolimus, and sirolimus in whole blood.

Journal: Therapeutic drug monitoring 20090201

Title: Novel role of the CXC chemokine receptor 3 in inflammatory response to arterial injury: involvement of mTORC1.

Journal: Circulation research 20090130

Title: Safety and pharmacokinetics of paclitaxel and the oral mTOR inhibitor everolimus in advanced solid tumours.

Journal: British journal of cancer 20090127

Title: Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53.

Journal: British journal of cancer 20090127

Title: Oral mTOR inhibitor everolimus in patients with gemcitabine-refractory metastatic pancreatic cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090110

Title: Glycemic control in patients with insulinoma treated with everolimus.

Journal: The New England journal of medicine 20090108

Title: Minimization protocols in pancreas transplantation.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20090101

Title: Calcineurin-inhibitor minimization protocols in heart transplantation.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20090101

Title: Assessment with optical coherence tomography of a new strategy for bifurcational lesion treatment: the Tryton Side-Branch Stent.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101

Title: San Antonio Breast Cancer Symposium.

Journal: The Lancet. Oncology 20090101

Title: Therapeutic strategy targeting the mTOR-HIF-1alpha-VEGF pathway in ovarian clear cell adenocarcinoma.

Journal: Pathology international 20090101

Title: Everolimus-associated pneumonitis in 3 heart transplant recipients.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20090101

Title: Graft-versus-host disease prophylaxis with everolimus and tacrolimus is associated with a high incidence of sinusoidal obstruction syndrome and microangiopathy: results of the EVTAC trial.

Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090101

Title: Cyclosporin A, but not everolimus, inhibits DNA repair in human fibroblasts and lymphoblasts.

Journal: International journal of clinical pharmacology and therapeutics 20090101

Title: [Topics in mTOR pathway and its inhibitors].

Journal: Bulletin du cancer 20090101

Title: Late conversion to everolimus complicated with necrotizing glomerulonephritis in a renal allograft recipient: case report.

Journal: Transplantation proceedings 20090101

Title: Everolimus in liver and lung transplantation.

Journal: Drugs of today (Barcelona, Spain : 1998) 20090101

Title: Assessment of the absorption process following bioabsorbable everolimus-eluting stent implantation: temporal changes in strain values and tissue composition using intravascular ultrasound radiofrequency data analysis. A substudy of the ABSORB clinical trial.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101

Title: A rapid HPLC-MS/MS method for the simultaneous quantification of cyclosporine A, tacrolimus, sirolimus and everolimus in human blood samples.

Journal: Nature protocols 20090101

Title: Larger dosage required for everolimus than sirolimus to maintain same blood concentration in two pancreatic islet transplant patients with tacrolimus.

Journal: Drug metabolism and pharmacokinetics 20090101

Title: Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells.

Journal: BMC cancer 20090101

Title: The influence of commonly used immunosuppressive drugs on the small bowel functions - a comparative experimental study.

Journal: Annals of transplantation 20090101

Title: Management of metabolic cytochrome P450 3A4 drug-drug interaction between everolimus and azole antifungals in a renal transplant patient.

Journal: Clinical drug investigation 20090101

Title: Equivalent benefit of mTORC1 blockade and combined PI3K-mTOR blockade in a mouse model of tuberous sclerosis.

Journal: Molecular cancer 20090101

Title: Combination of everolimus and tacrolimus in kidney transplant patients with intolerance to mycophenolate mofetil/mycophenolic acid.

Journal: Transplantation proceedings 20090101

Title: De novo kidney transplant recipients need higher doses of Advagraf compared with Prograf to get therapeutic levels.

Journal: Transplantation proceedings 20090101

Title: Conversion to everolimus in kidney transplant recipients with decreased renal function.

Journal: Transplantation proceedings 20090101

Title: Sirolimus and everolimus induced pneumonitis in adult renal allograft recipients: experience in a center.

Journal: Transplantation proceedings 20090101

Title: Indications and management of everolimus after liver transplantation.

Journal: Transplantation proceedings 20090101

Title: Efficacy, tolerance, and safety of mammalian target of rapamycin inhibitors as rescue immunosuppressants in liver transplantation.

Journal: Transplantation proceedings 20090101

Title: Everolimus represents an advance in immunosuppression for patients who have developed cancer after renal transplantation.

Journal: Transplantation proceedings 20090101

Title: Complete switch to everolimus in long-term kidney transplants: evolution of the renal function.

Journal: Transplantation proceedings 20090101

Title: FTY720 and everolimus in de novo renal transplant patients at risk for delayed graft function: results of an exploratory one-yr multicenter study.

Journal: Clinical transplantation 20090101

Title: Chronic allograft nephropathy--a clinical syndrome: early detection and the potential role of proliferation signal inhibitors.

Journal: Clinical transplantation 20090101

Title: Can proliferation signal inhibitor-induced Tregs really reflect transplantation tolerance in clinical solid organ transplantation?

Journal: International reviews of immunology 20090101

Title: Effects of everolimus on cytokines, oxidative stress, and renal histology in ischemia-reperfusion injury of the kidney.

Journal: Renal failure 20090101

Title: [Pneumonitis caused by sirolimus: improvement after switching to everolimus].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20090101

Title: Adherence must always be considered: is everolimus really ineffective as a treatment for atopic dermatitis?

Journal: The Journal of dermatological treatment 20090101

Title: Severe atopic dermatitis treated with everolimus.

Journal: The Journal of dermatological treatment 20090101

Title: Update on the everolimus-eluting coronary stent system: results and implications from the SPIRIT clinical trial program.

Journal: Vascular health and risk management 20090101

Title: Overview of the 2007 Food and Drug Administration Circulatory System Devices Panel meeting on the Xience V Everolimus-Eluting Coronary Stent.

Journal: The American journal of cardiology 20081215

Title: Recovery of tacrolimus-associated brachial neuritis after conversion to everolimus in a pediatric renal transplant recipient--case report and review of the literature.

Journal: Pediatric transplantation 20081201

Title: Blockade of mTOR signaling potentiates the ability of histone deacetylase inhibitor to induce growth arrest and differentiation of acute myelogenous leukemia cells.

Journal: Leukemia 20081201

Title: Laryngeal transplantation in the setting of cancer: a rat model.

Journal: The Laryngoscope 20081201

Title: Deforolimus (AP23573) a novel mTOR inhibitor in clinical development.

Journal: Expert opinion on investigational drugs 20081201

Title: Is there a preferable DES in diabetic patients? A critical appraisal of the evidence.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081201

Title: Proliferation signal inhibitor-induced decrease of vascular endothelial cadherin expression and increase of endothelial permeability in vitro are prevented by an anti-oxidant.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20081201

Title: [Everolimus (RAD001) and solid tumours: a 2008 summary].

Journal: Bulletin du cancer 20081201

Title: Treatment of chronic allograft nephropathy at late stages using everolimus or FTY720 in combination with cyclosporine.

Journal: Transplantation proceedings 20081201

Title: Late stent recoil of the bioabsorbable everolimus-eluting coronary stent and its relationship with plaque morphology.

Journal: Journal of the American College of Cardiology 20081111

Title: A mathematical model for predicting drug release from a biodurable drug-eluting stent coating.

Journal: Journal of biomedical materials research. Part A 20081101

Title: Differential promotion of hematopoietic chimerism and inhibition of alloreactive T cell proliferation by combinations of anti-CD40Ligand, anti-LFA-1, everolimus, and deoxyspergualin.

Journal: Transplant immunology 20081101

Title: Prolonged insulin independence after islet allotransplants in recipients with type 1 diabetes.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20081101

Title: Pharmacokinetic interaction between everolimus and antifungal triazoles in a liver transplant patient.

Journal: The Annals of pharmacotherapy 20081101

Title: Switch of immunosuppression from cyclosporine A to everolimus: impact on pulse wave velocity in stable de-novo renal allograft recipients.

Journal: Journal of hypertension 20081101

Title: Systemic therapy for metastatic renal cell carcinoma.

Journal: The Urologic clinics of North America 20081101

Title: [67-year-old patient with speech disorder and dysphagia].

Journal: Deutsche medizinische Wochenschrift (1946) 20081101

Title: Tolerance profile of the proliferation signal inhibitors everolimus and sirolimus in heart transplantation.

Journal: Transplantation proceedings 20081101

Title: Preliminary experience with conversion from calcineurin inhibitors to everolimus in cardiac transplantation maintenance therapy.

Journal: Transplantation proceedings 20081101

Title: Use of everolimus in de novo renal recipients: initial experience in the Greek population.

Journal: Transplantation proceedings 20081101

Title: Metabolic changes following conversion from an anticalcineurin-based therapy to an everolimus-based one: a single-center experience.

Journal: Transplantation proceedings 20081101

Title: One year follow-up of steroid-free immunosuppression plus everolimus in isolated pancreas transplantation.

Journal: Transplantation 20081027

Title: Severe everolimus-associated pneumonitis in a renal transplant recipient.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081001

Title: Bioabsorbable drug-eluting stents: the future of coronary angioplasty?

Journal: Nature clinical practice. Cardiovascular medicine 20081001

Title: Prolongation of corneal allograft survival by topical application of everolimus in experimental keratoplasty.

Journal: Ophthalmic research 20081001

Title: Everolimus- and zotarolimus-eluting stents for bare metal stent in-stent restenosis treatment: a prospective study.

Journal: Journal of interventional cardiology 20081001

Title: Novel drugs for renal cell carcinoma.

Journal: Expert opinion on investigational drugs 20081001

Title: Systemic exposure of everolimus after stent implantation: a pharmacokinetic study.

Journal: American heart journal 20081001

Title: Avoidance of calcineurin inhibitors with use of proliferation signal inhibitors in de novo heart transplantation with renal failure.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20081001

Title: Heart transplantation under cyclosporine or tacrolimus combined with mycophenolate mofetil or everolimus.

Journal: Transplantation proceedings 20081001

Title: Out with the old, in with the new: immunosuppression minimization in children.

Journal: Current opinion in organ transplantation 20081001

Title: Efficacy of RAD001 (everolimus) and octreotide LAR in advanced low- to intermediate-grade neuroendocrine tumors: results of a phase II study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080910

Title: Major treatment improvements encourage kidney cancer researchers to seek further gains.

Journal: Journal of the National Cancer Institute 20080903

Title: Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer.

Journal: The Journal of clinical investigation 20080902

Title: Positive reasons for publishing negative findings.

Journal: The American journal of gastroenterology 20080901

Title: A multicenter, randomized, double-blind trial of everolimus versus azathioprine and placebo to maintain steroid-induced remission in patients with moderate-to-severe active Crohn's disease.

Journal: The American journal of gastroenterology 20080901

Title: Everolimus (RAD001) and anti-angiogenic cyclophosphamide show long-term control of gastric cancer growth in vivo.

Journal: Cancer biology & therapy 20080901

Title: Sirolimus-induced aphthous ulcers which disappeared with conversion to everolimus.

Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20080901

Title: mTOR inhibitors and unilateral edema.

Journal: Revista espanola de cardiologia 20080901

Title: Everolimus with reduced-dose cyclosporine in de novo renal transplant recipients: Philippine experience.

Journal: Transplantation proceedings 20080901

Title: NCCN Task Force Report: mTOR inhibition in solid tumors.

Journal: Journal of the National Comprehensive Cancer Network : JNCCN 20080901

Title: Clinical investigations in T-cell and NK-cell non-Hodgkin lymphoma.

Journal: Clinical advances in hematology & oncology : H&O 20080901

Title: Progression-free survival as endpoint in metastatic RCC?

Journal: Lancet (London, England) 20080809

Title: Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial.

Journal: Lancet (London, England) 20080809

Title: Everolimus in patients with rheumatoid arthritis receiving concomitant methotrexate: a 3-month, double-blind, randomised, placebo-controlled, parallel-group, proof-of-concept study.

Journal: Annals of the rheumatic diseases 20080801

Title: The macrolide everolimus forms an unusual metabolite in animals and humans: identification of a phosphocholine ester.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20080801

Title: In-vitro synergism of m-TOR inhibitors, statins, and classical chemotherapy: potential implications in acute leukemia.

Journal: Anti-cancer drugs 20080801

Title: Corneal permeation studies of everolimus microemulsion.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20080801

Title: Conversion from sirolimus to everolimus in maintenance renal transplant recipients within a calcineurin inhibitor-free regimen: results of a 6-month pilot study.

Journal: Clinical nephrology 20080801

Title: Endothelial cell recovery between comparator polymer-based drug-eluting stents.

Journal: Journal of the American College of Cardiology 20080729

Title: Beneficial effect of omega-3 fatty acids on sirolimus- or everolimus-induced hypertriglyceridemia in heart transplant recipients.

Journal: Transplantation 20080727

Title: Clinical trials probe new therapies for some difficult-to-treat cancers.

Journal: JAMA 20080723

Title: Fluvastatin synergistically improves the antiproliferative effect of everolimus on rat smooth muscle cells by altering p27Kip1/cyclin E expression.

Journal: Molecular pharmacology 20080701

Title: Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer.

Journal: Autophagy 20080701

Title: Mammalian target of rapamycin inhibitor dyslipidemia in kidney transplant recipients.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080701

Title: Everolimus-related pulmonary toxicity in heart transplant recipients.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080701

Title: Oral everolimus inhibits neointimal proliferation in prosthetic pulmonary valved stents in pigs.

Journal: The Journal of heart valve disease 20080701

Title: PTEN loss does not predict for response to RAD001 (Everolimus) in a glioblastoma orthotopic xenograft test panel.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080615

Title: Everolimus for refractory Crohn's disease: a case report.

Journal: Inflammatory bowel diseases 20080601

Title: Simultaneous quantification of cyclosporine, tacrolimus, sirolimus and everolimus in whole blood by liquid chromatography-electrospray mass spectrometry.

Journal: Clinical biochemistry 20080601

Title: RAD001 (Everolimus) inhibits growth of prostate cancer in the bone and the inhibitory effects are increased by combination with docetaxel and zoledronic acid.

Journal: The Prostate 20080601

Title: Pharmacodynamic effects of everolimus on anti-CD3 antibody-stimulated T-lymphocyte proliferation and interleukin-10 synthesis in stable kidney-transplant patients.

Journal: Cytokine 20080601

Title: Multicenter trial of everolimus in pediatric renal transplant recipients: results at three year.

Journal: Pediatric transplantation 20080601

Title: Drug reactions - new observations.

Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20080601

Title: Everolimus: an update on the mechanism of action, pharmacokinetics and recent clinical trials.

Journal: Expert opinion on drug metabolism & toxicology 20080601

Title: Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080521

Title: Prevention of atherosclerosis by the mTOR inhibitor everolimus in LDLR-/- mice despite severe hypercholesterolemia.

Journal: Atherosclerosis 20080501

Title: Coronary aneurysm formation in a patient early after everolimus-eluting stent implantation.

Journal: The Journal of invasive cardiology 20080501

Title: Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors.

Journal: Molecular cancer therapeutics 20080501

Title: Comparison of an everolimus-eluting stent and a paclitaxel-eluting stent in patients with coronary artery disease: a randomized trial.

Journal: JAMA 20080423

Title: Next-generation drug-eluting stents: a spirited step forward or more of the same.

Journal: JAMA 20080423

Title: Trends in adult post-kidney transplant immunosuppressive use in Australia, 1991-2005.

Journal: Nephrology (Carlton, Vic.) 20080401

Title: Identifying optimal biologic doses of everolimus (RAD001) in patients with cancer based on the modeling of preclinical and clinical pharmacokinetic and pharmacodynamic data.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080401

Title: Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: a phase I tumor pharmacodynamic study in patients with advanced solid tumors.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080401

Title: Phase I pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080401

Title: Preclinical evidences suggest new treatment options for endocrine disorders: Pasireotide (SOM230) and Everolimus (RAD001).

Journal: Annales d'endocrinologie 20080401

Title: Conversion therapy to everolimus in renal transplant recipients: results after one year.

Journal: Transplantation proceedings 20080401

Title: Drug essentials mTOR inhibitors.

Journal: Oncology (Williston Park, N.Y.) 20080401

Title: Multicenter, randomized study of the use of everolimus with tacrolimus after renal transplantation demonstrates its effectiveness.

Journal: Transplantation 20080327

Title: Biodegradable drug-eluting stents: promises and pitfalls.

Journal: Lancet (London, England) 20080315

Title: A bioabsorbable everolimus-eluting coronary stent system for patients with single de-novo coronary artery lesions (ABSORB): a prospective open-label trial.

Journal: Lancet (London, England) 20080315

Title: Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugs.

Journal: British journal of cancer 20080311

Title: Delta-24-RGD in combination with RAD001 induces enhanced anti-glioma effect via autophagic cell death.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20080301

Title: A randomized exploratory trial of steroid avoidance in renal transplant patients treated with everolimus and low-dose cyclosporine.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080201

Title: Everolimus exposure in cardiac transplant recipients is influenced by concomitant calcineurin inhibitor.

Journal: Therapeutic drug monitoring 20080201

Title: Antiangiogenic therapy with mammalian target of rapamycin inhibitor RAD001 (Everolimus) increases radiosensitivity in solid cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080201

Title: Pulmonary complications of novel antineoplastic agents for solid tumors.

Journal: Chest 20080201

Title: Multidisciplinary insights on clinical guidance for the use of proliferation signal inhibitors in heart transplantation.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080201

Title: Cyclosporine reduction in the presence of everolimus: 3-month data from a Canadian pilot study of maintenance cardiac allograft recipients.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080201

Title: The potential role of mTOR inhibitors in non-small cell lung cancer.

Journal: The oncologist 20080201

Title: Percutaneous coronary intervention with everolimus-eluting stents (Xience V): systematic review and direct-indirect comparison meta-analyses with paclitaxel-eluting stents (Taxus) and sirolimus-eluting stents (Cypher).

Journal: Minerva cardioangiologica 20080201

Title: Future stent drug delivery systems.

Journal: Minerva cardioangiologica 20080201

Title: Next-generation drug-eluting stents in coronary artery disease: focus on everolimus-eluting stent (Xience V).

Journal: Vascular health and risk management 20080201

Title: Mammalian target of rapamycin is the key effector of phosphatidylinositol-3-OH-initiated proliferative signals in the thyroid follicular epithelium.

Journal: Cancer research 20080115

Title: Mammalian target of rapamycin (mTOR) inhibition activates phosphatidylinositol 3-kinase/Akt by up-regulating insulin-like growth factor-1 receptor signaling in acute myeloid leukemia: rationale for therapeutic inhibition of both pathways.

Journal: Blood 20080101

Title: Octreotide and the mTOR inhibitor RAD001 (everolimus) block proliferation and interact with the Akt-mTOR-p70S6K pathway in a neuro-endocrine tumour cell Line.

Journal: Neuroendocrinology 20080101

Title: The oral mTOR inhibitor RAD001 (everolimus) in combination with letrozole in patients with advanced breast cancer: results of a phase I study with pharmacokinetics.

Journal: European journal of cancer (Oxford, England : 1990) 20080101

Title: Huge right atrial thrombus 6 years after heart transplantation.

Journal: The Annals of thoracic surgery 20080101

Title: San Antonio Breast Cancer Symposium.

Journal: The Lancet. Oncology 20080101

Title: A sensitive high-throughput HPLC assay for simultaneous determination of everolimus and clobetasol propionate.

Journal: Journal of chromatographic science 20080101

Title: The mTOR inhibitor everolimus attenuates the time course of chronic anti-Thy1 nephritis in the rat.

Journal: Nephron. Experimental nephrology 20080101

Title: Early, abrupt conversion of de novo renal transplant patients from cyclosporine to everolimus: results of a pilot study.

Journal: Clinical transplantation 20080101

Title: mTOR inhibitors and calcineurin inhibitors do not affect adhesion molecule expression of human macro- and microvascular endothelial cells.

Journal: Journal of vascular research 20080101

Title: Drug-eluting stents - what should be improved?

Journal: Annals of medicine 20080101

Title: Stability of sirolimus and everolimus measured by immunoassay techniques in whole blood samples from kidney transplant patients.

Journal: International journal of immunopathology and pharmacology 20080101

Title: Meta-analysis shows similar risk of thrombosis after drug-eluting stent, bare-metal stent, or angioplasty.

Journal: Endothelium : journal of endothelial cell research 20080101

Title: Comparison between a liquid chromatography-tandem mass spectrometry assay and a fluorescent polarization immunoassay to measure whole blood everolimus concentration in heart and renal transplantations.

Journal: Journal of clinical laboratory analysis 20080101

Title: Mammalian target of rapamycin as a target in hematological malignancies.

Journal: Current problems in cancer 20080101

Title: Effects of everolimus monotherapy on hematological parameters and iron homeostasis in de novo liver transplant recipients: preliminary results.

Journal: Transplantation proceedings 20080101

Title: The South African branch of the Crossroads Institute celebrates it second birthday.

Journal: Cardiovascular journal of Africa 20080101

Title: Influence of interactions between immunosuppressive drugs on therapeutic drug monitoring.

Journal: Annals of transplantation 20080101

Title: Quantification of sirolimus and everolimus by immunoassay techniques: test specificity and cross-reactivity evaluation.

Journal: International journal of immunopathology and pharmacology 20080101

Title: Signaling inhibitors in metastatic renal cell carcinoma.

Journal: Cancer journal (Sudbury, Mass.) 20080101

Title: Effects of everolimus as an antiproliferative agent on regression of encapsulating peritoneal sclerosis in a rat model.

Journal: Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20080101

Title: Failure of systematic error detection with internal quality control program.

Journal: Annals of clinical and laboratory science 20080101

Title: [Chronic allograft dysfunction: role of immunosuppressive treatment].

Journal: Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20080101

Title: [ASCO 2008. Bevacizumab in advanced renal carcinoma].

Journal: Tumori 20080101

Title: Effect of intestinal and hepatic first-pass extraction on the pharmacokinetics of everolimus in rats.

Journal: Drug metabolism and pharmacokinetics 20080101

Title: mTOR inhibition sensitizes gastric cancer to alkylating chemotherapy in vivo.

Journal: Anticancer research 20080101

Title: A lower incidence of cytomegalovirus infection in de novo heart transplant recipients randomized to everolimus.

Journal: Transplantation 20071215

Title: The mTOR inhibitor everolimus induces proteinuria and renal deterioration in the remnant kidney model in the rat.

Journal: Transplantation 20071215

Title: Crossreactivity of isolated everolimus metabolites with the Innofluor Certican immunoassay for therapeutic drug monitoring of everolimus.

Journal: Therapeutic drug monitoring 20071201

Title: [mTOR signal pathway and its inhibitors in antitumor therapy: a review].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20071201

Title: Proliferation signal inhibitors in transplantation: questions at the cutting edge of everolimus therapy.

Journal: Transplantation proceedings 20071201

Title: Economic evaluation of everolimus and mycophenolate mofetil versus azathioprine in de novo heart transplantation.

Journal: Transplantation proceedings 20071201

Title: Switch to everolimus for sirolimus-induced pneumonitis in a liver transplant recipient--not all proliferation signal inhibitors are the same: a case report.

Journal: Transplantation proceedings 20071201

Title: Everolimus-associated interstitial pneumonitis in a patient with a heart transplant.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20071101

Title: Post-renal transplant hemolytic uremic syndrome following combination therapy with tacrolimus and everolimus.

Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20071101

Title: A randomized phase II study of pemetrexed or RAD001 as second-line treatment of advanced non-small-cell lung cancer in elderly patients: treatment rationale and protocol dynamics.

Journal: Clinical lung cancer 20071101

Title: Phase I study of everolimus in pediatric patients with refractory solid tumors.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071020

Title: Comparison of in vivo acute stent recoil between the bioabsorbable everolimus-eluting coronary stent and the everolimus-eluting cobalt chromium coronary stent: insights from the ABSORB and SPIRIT trials.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001

Title: Rapamycin: something old, something new, sometimes borrowed and now renewed.

Journal: Clinical pharmacology and therapeutics 20071001

Title: Polymeric stents: degradable but strong.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001

Title: Identification of everolimus metabolite patterns in trough blood samples of kidney transplant patients.

Journal: Therapeutic drug monitoring 20071001

Title: Internal standard selection for the high-performance liquid chromatography tandem mass spectroscopy assay of everolimus in blood.

Journal: Therapeutic drug monitoring 20071001

Title: Preclinical testing of clinically applicable strategies for overcoming trastuzumab resistance caused by PTEN deficiency.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20071001

Title: Use of everolimus as a rescue immunosuppressive therapy in liver transplant patients with neoplasms.

Journal: Transplantation 20070927

Title: The combination of novel low molecular weight inhibitors of RAF (LBT613) and target of rapamycin (RAD001) decreases glioma proliferation and invasion.

Journal: Molecular cancer therapeutics 20070901

Title: Fatal Epstein-Barr virus-associated lymphoproliferative disorder following treatment with a novel mTOR inhibitor for relapsed chronic lymphocytic leukemia leukemia cells.

Journal: Haematologica 20070901

Title: Prospective assessment of discontinuation and reinitiation of erlotinib or gefitinib in patients with acquired resistance to erlotinib or gefitinib followed by the addition of everolimus.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070901

Title: mTOR inhibitors: do they help preserve renal function?

Journal: Transplantation proceedings 20070901

Title: Evaluation of the efficacy and safety of the conversion from a calcineurin inhibitor to an everolimus-based therapy in maintenance renal transplant patients.

Journal: Transplantation proceedings 20070901

Title: Use of the new proliferation signal inhibitor everolimus in renal transplant patients in Spain: preliminary results of the EVERODATA registry.

Journal: Transplantation proceedings 20070901

Title: Study of anemia after late introduction of everolimus in the immunosuppressive treatment of renal transplant patients.

Journal: Transplantation proceedings 20070901

Title: mTOR inhibitors and their secondary effects in cardiac transplant recipients: a descriptive study.

Journal: Transplantation proceedings 20070901

Title: Sirolimus in renal transplantation.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070901

Title: Sunitinib, sorafenib and mTOR inhibitors in renal cancer.

Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20070901

Title: [3/3 Inhibitors of mTOR (sirolimus and everolimus)].

Journal: Soins; la revue de reference infirmiere 20070901

Title: Combination of the oncolytic adenovirus ICOVIR-5 with chemotherapy provides enhanced anti-glioma effect in vivo.

Journal: Cancer gene therapy 20070801

Title: Phase 1 trial of everolimus and gefitinib in patients with advanced nonsmall-cell lung cancer.

Journal: Cancer 20070801

Title: Modulation of cholesterol homeostasis by antiproliferative drugs in human pterygium fibroblasts.

Journal: Investigative ophthalmology & visual science 20070801

Title: Rationale for a phase I trial of erlotinib and the mammalian target of rapamycin inhibitor everolimus (RAD001) for patients with relapsed non small cell lung cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070801

Title: mTOR in tuberous sclerosis and other neurological disorders.

Journal: Epilepsia 20070801

Title: Akt-induced endocrine therapy resistance is reversed by inhibition of mTOR signaling.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20070801

Title: The biology behind mTOR inhibition in sarcoma.

Journal: The oncologist 20070801

Title: Mechanisms of mammalian target of rapamycin inhibition in sarcoma: present and future.

Journal: Expert review of anticancer therapy 20070801

Title: RAD001 inhibits human ovarian cancer cell proliferation, enhances cisplatin-induced apoptosis, and prolongs survival in an ovarian cancer model.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070715

Title: The role of mTOR inhibitors for treatment of sarcomas.

Journal: Current oncology reports 20070701

Title: Uneventful thoracic healing with everolimus after aortic valve replacement.

Journal: The Annals of thoracic surgery 20070701

Title: Interleukin-17 and airway inflammation: a longitudinal airway biopsy study after lung transplantation.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070701

Title: Observational study with everolimus (Certican) in combination with low-dose cyclosporine in de novo heart transplant recipients.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070701

Title: Physiologically based pharmacokinetic (PBPK) modeling of everolimus (RAD001) in rats involving non-linear tissue uptake.

Journal: Journal of pharmacokinetics and pharmacodynamics 20070601

Title: mTOR-inhibitors simultaneously inhibit proliferation and basal IL-6 synthesis of human coronary artery endothelial cells.

Journal: International immunopharmacology 20070601

Title: Assessment and validation of the MS/MS fragmentation patterns of the macrolide immunosuppressant everolimus.

Journal: Journal of mass spectrometry : JMS 20070601

Title: Prevention of acute rejection and allograft vasculopathy by everolimus in cardiac transplants recipients: a 24-month analysis.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070601

Title: Possible everolimus-induced, severe, reversible encephalopathy after cardiac transplantation.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070601

Title: Comparison of fluorescent polarization immunoassay (FPIA) versus HPLC to measure everolimus blood concentrations in clinical transplantation.

Journal: Clinica chimica acta; international journal of clinical chemistry 20070501

Title: An in vitro cytologic assay for evaluation of the KIT signaling pathway in gastrointestinal stromal tumors.

Journal: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20070501

Title: Reversal of loss of glomerular filtration rate in children with transplant nephropathy after switch to everolimus and low-dose cyclosporine A.

Journal: Pediatric transplantation 20070501

Title: Therapeutic effect of a new immunosuppressive agent, everolimus, on interleukin-10 gene-deficient mice with colitis.

Journal: Clinical and experimental immunology 20070501

Title: Kaposi's sarcoma in renal transplant recipients--the impact of proliferation signal inhibitors.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501

Title: Use of proliferation signal inhibitors in non-melanoma skin cancer following renal transplantation.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501

Title: Post-transplant lymphoproliferative disorder--the potential of proliferation signal inhibitors.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501

Title: Use of proliferation signal inhibitors in the management of post-transplant malignancies--clinical guidance.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501

Title: Clinical development of mTOR inhibitors: a focus on lymphoma.

Journal: Reviews on recent clinical trials 20070501

Title: Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML.

Journal: Blood 20070415

Title: A HPLC-mass spectrometric method suitable for the therapeutic drug monitoring of everolimus.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070401

Title: Gonadal impact of target of rapamycin inhibitors (sirolimus and everolimus) in male patients: an overview.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20070401

Title: PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr.

Journal: International immunology 20070401

Title: Recommendations for the use of everolimus (Certican) in heart transplantation: results from the second German-Austrian Certican Consensus Conference.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070401

Title: Conversion from a calcineurin inhibitor-based immunosuppressive regimen to everolimus in renal transplant recipients: effect on renal function and proteinuria.

Journal: Transplantation proceedings 20070401

Title: Case report of a kidney transplant recipient converted to everolimus due to malignancy: resolution of bronchiolitis obliterans organizing pneumonia without everolimus discontinuation.

Journal: Transplantation proceedings 20070401

Title: RAD001 (Everolimus) delays tumor onset and progression in a transgenic mouse model of ovarian cancer.

Journal: Cancer research 20070315

Title: Modeling of degradation and drug release from a biodegradable stent coating.

Journal: Journal of biomedical materials research. Part A 20070301

Title: Proliferation signal inhibitors in cardiac transplantation.

Journal: Current opinion in cardiology 20070301

Title: New advances in antirejection therapy.

Journal: Current opinion in cardiology 20070301

Title: Reduced progression of endometrial hyperplasia with oral mTOR inhibition in the Pten heterozygote murine model.

Journal: American journal of obstetrics and gynecology 20070301

Title: Calcineurin inhibitor-free immunosuppression using everolimus (Certican) in maintenance heart transplant recipients: 6 months' follow-up.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070301

Title: Effects of everolimus on cellular and humoral immune processes leading to chronic allograft nephropathy in a rat model with sensitized recipients.

Journal: Transplantation 20070227

Title: Selective clearance of macrophages in atherosclerotic plaques by autophagy.

Journal: Journal of the American College of Cardiology 20070213

Title: Antiproliferative activity of RAD001 (everolimus) as a single agent and combined with other agents in mantle cell lymphoma.

Journal: Leukemia 20070201

Title: Severe psoriasis treated with a new macrolide: everolimus.

Journal: The British journal of dermatology 20070201

Title: Impact of pharmacometric reviews on new drug approval and labeling decisions--a survey of 31 new drug applications submitted between 2005 and 2006.

Journal: Clinical pharmacology and therapeutics 20070201

Title: Combination of sublethal concentrations of epidermal growth factor receptor inhibitor and microtubule stabilizer induces apoptosis of glioblastoma cells.

Journal: Molecular cancer therapeutics 20070201

Title: Determination of everolimus in whole blood using the Abbott IMx sirolimus microparticle enzyme immunoassay.

Journal: Clinical biochemistry 20070101

Title: First-in-human implantation of a fully bioabsorbable drug-eluting stent: the BVS poly-L-lactic acid everolimus-eluting coronary stent.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070101

Title: Everolimus is a potent inducer of erythroid differentiation and gamma-globin gene expression in human erythroid cells.

Journal: Acta haematologica 20070101

Title: No robust conclusions to be drawn from clinical trials in the absence of an adequate control group.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20070101

Title: 12-month safety and efficacy of everolimus with reduced exposure cyclosporine in de novo renal transplant recipients.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20070101

Title: XIENCE V everolimus-eluting coronary stent system: a novel second generation drug-eluting stent.

Journal: Expert review of medical devices 20070101

Title: Everolimus-induced mTOR inhibition selectively depletes macrophages in atherosclerotic plaques by autophagy.

Journal: Autophagy 20070101

Title: The novel mTOR inhibitor RAD001 (everolimus) induces antiproliferative effects in human pancreatic neuroendocrine tumor cells.

Journal: Neuroendocrinology 20070101

Title: Do the benefits outweigh the risks with drug-eluting stents?

Journal: Scandinavian cardiovascular journal : SCJ 20070101

Title: Immunosuppression on the horizon.

Journal: Heart failure clinics 20070101

Title: Everolimus retards cyst growth and preserves kidney function in a rodent model for polycystic kidney disease.

Journal: Kidney & blood pressure research 20070101

Title: Comparison of sirolimus and everolimus in their effects on blood lipid profiles and haematological parameters in heart transplant recipients.

Journal: Clinical transplantation 20070101

Title: Immunosuppression for lung transplantation: evidence to date.

Journal: Drugs 20070101

Title: Higher incidence of acute rejection in renal transplant recipients with low everolimus exposure.

Journal: Transplantation proceedings 20070101

Title: Possible role of everolimus in improving renal function in long-term heart transplantation.

Journal: Transplantation proceedings 20070101

Title: Everolimus and mycophenolate mofetil sensitize human pancreatic cancer cells to gemcitabine in vitro: a novel adjunct to standard chemotherapy?

Journal: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20070101

Title: RAD inhibition of sarcoma growth: implications for laryngeal transplantation.

Journal: American journal of otolaryngology 20070101

Title: Newer stents: looking at the horizon.

Journal: Indian heart journal 20070101

Title: Affects of immunosuppression on circulating dendritic cells: an adjunct to therapeutic drug monitoring after heart transplantation.

Journal: International immunopharmacology 20061220

Title: Everolimus interferes with healing of experimental intestinal anastomoses.

Journal: Transplantation 20061215

Title: Targeting von Hippel-Lindau pathway in renal cell carcinoma.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20061215

Title: Everolimus drug interactions: application of a classification system for clinical decision making.

Journal: Biopharmaceutics & drug disposition 20061201

Title: Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling.

Journal: The Journal of biological chemistry 20061201

Title: Comparison of the Innofluor certican assay with HPLC-UV for the determination of everolimus concentrations in heart transplantation.

Journal: Clinical biochemistry 20061201

Title: Differential effects of immunosuppressive drugs on T-cell motility.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20061201

Title: Targeting the AIB1 oncogene through mammalian target of rapamycin inhibition in the mammary gland.

Journal: Cancer research 20061201

Title: The role of therapeutic drug monitoring in individualizing immunosuppressive drug therapy: recent developments.

Journal: Therapeutic drug monitoring 20061201

Title: Differential pharmacokinetic interaction of tacrolimus and cyclosporine on everolimus.

Journal: Transplantation proceedings 20061201

Title: Exposure-efficacy relationships of a fingolimod-everolimus regimen in kidney transplant patients at risk for delayed graft function.

Journal: Transplantation proceedings 20061201

Title: Safety, tolerability, and efficacy of everolimus in de novo liver transplant recipients: 12- and 36-month results.

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20061101

Title: Inclusion of MPA and in a rapid multi-drug LC-tandem mass spectrometric method for simultaneous determination of immunosuppressants.

Journal: Clinica chimica acta; international journal of clinical chemistry 20061101

Title: Everolimus and mTOR inhibitors in liver transplantation: opening the 'box'.

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20061101

Title: A monoselective sphingosine-1-phosphate receptor-1 agonist prevents allograft rejection in a stringent rat heart transplantation model.

Journal: Chemistry & biology 20061101

Title: Beyond imatinib: second generation c-KIT inhibitors for the management of gastrointestinal stromal tumors.

Journal: Clinical colorectal cancer 20061101

Title: Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells.

Journal: Cancer research 20061015

Title: Everolimus inhibits glomerular endothelial cell proliferation and VEGF, but not long-term recovery in experimental thrombotic microangiopathy.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20061001

Title: Calcineurin-inhibitor induced pain syndrome after organ transplantation.

Journal: Kidney international 20061001

Title: The antitumor effects of sunitinib (formerly SU11248) against a variety of human hematologic malignancies: enhancement of growth inhibition via inhibition of mammalian target of rapamycin signaling.

Journal: Molecular cancer therapeutics 20061001

Title: Mammalian target of rapamycin inhibitors in combination with letrozole in breast cancer.

Journal: Clinical breast cancer 20061001

Title: Conversion to everolimus in kidney transplant recipients: a safe and simple procedure.

Journal: Transplantation proceedings 20061001

Title: Conversion from calcineurin inhibitors to everolimus in kidney transplant recipients with malignant neoplasia.

Journal: Transplantation proceedings 20061001

Title: Fibroblasts isolated from human pterygia exhibit altered lipid metabolism characteristics.

Journal: Experimental eye research 20060901

Title: Mammalian target of rapamycin inhibition induces cell cycle arrest in diffuse large B cell lymphoma (DLBCL) cells and sensitises DLBCL cells to rituximab.

Journal: British journal of haematology 20060901

Title: Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060901

Title: Therapeutic targets: MTOR and related pathways.

Journal: Cancer biology & therapy 20060901

Title: Influence of everolimus on cyclosporine Neoral pharmacokinetics in Chinese de novo cardiac transplant recipients.

Journal: Transplantation proceedings 20060901

Title: Therapeutic drug monitoring of cyclosporine Neoral in de novo Chinese cardiac transplant recipients treated with an everolimus-cyclosporine immunosuppressive regimen.

Journal: Transplantation proceedings 20060901

Title: Effect of everolimus-eluting stents in different vessel sizes (from the pooled FUTURE I and II trials).

Journal: The American journal of cardiology 20060815

Title: Effects of a combined treatment with mTOR inhibitor RAD001 and tamoxifen in vitro on growth and apoptosis of human cancer cells.

Journal: Gynecologic oncology 20060801

Title: Everolimus alters imatinib blood partition in favour of the erythrocyte.

Journal: The Journal of pharmacy and pharmacology 20060801

Title: Sensitive, high throughput HPLC-MS/MS method with on-line sample clean-up for everolimus measurement.

Journal: Therapeutic drug monitoring 20060801

Title: Evaluation of a fluorescent polarization immunoassay for whole blood everolimus determination using samples from renal transplant recipients.

Journal: Clinical biochemistry 20060701

Title: Experimental efficacy of an everolimus eluting cobalt chromium stent.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060701

Title: Everolimus: an immunosuppressive agent in transplantation.

Journal: Expert opinion on pharmacotherapy 20060701

Title: Potential role of proliferation signal inhibitors on atherosclerosis in renal transplant patients.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701

Title: Everolimus in clinical practice--renal transplantation.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701

Title: Conversion to everolimus in maintenance patients--current clinical strategies.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701

Title: Conversion to a proliferation signal inhibitor in a patient with coronary artery disease--a case report.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701

Title: Conversion to everolimus in a patient with arterial hypertension and recurrent cutaneous neoplasia--a case report.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701

Title: Long-term cardiovascular risk in transplantation--insights from the use of everolimus in heart transplantation.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701

Title: Everolimus and reduced cyclosporine trough levels in maintenance heart transplant recipients.

Journal: Transplant immunology 20060601

Title: Recent developments in targeting the mammalian target of rapamycin (mTOR) kinase pathway.

Journal: Anti-cancer drugs 20060601

Title: Targeting mTOR for cancer treatment.

Journal: Current opinion in investigational drugs (London, England : 2000) 20060601

Title: Switching immunosuppressive drugs in kidney transplant recipients: 'show me the evidence'.

Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20060601

Title: Everolimus (RAD) inhibits in vivo growth of murine squamous cell carcinoma (SCC VII).

Journal: The Laryngoscope 20060501

Title: Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer.

Journal: Molecular cancer therapeutics 20060501

Title: Cutaneous leukocytoclastic vasculitis in a patient with myelodysplastic syndrome after therapy with the rapamycin analogue everolimus: case report and review of the literature.

Journal: Leukemia & lymphoma 20060501

Title: Long-term results of kidney transplantation with cyclosporine- and everolimus-based immunosuppression.

Journal: Transplantation proceedings 20060501

Title: Target of rapamycin inhibitors (TOR-I; sirolimus and everolimus) for primary immunosuppression in kidney transplant recipients.

Journal: The Cochrane database of systematic reviews 20060419

Title: Everolimus in pulmonary transplantation: pharmacokinetics and exposure-response relationships.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060401

Title: Resolution of sirolimus-induced pneumonitis after conversion to everolimus.

Journal: Transplantation proceedings 20060401

Title: Antiproliferative and overadditive effects of everolimus and mycophenolate mofetil in pancreas and lung cancer cells in vitro.

Journal: Transplantation proceedings 20060401

Title: Recommendations for use of everolimus after heart transplantation: results from a Latin-American Consensus Meeting.

Journal: Transplantation proceedings 20060401

Title: Future directions in the treatment of hormone-sensitive advanced breast cancer: the RAD001 (Everolimus)-letrozole clinical program.

Journal: Seminars in oncology 20060401

Title: New drug application 21-628, Certican (everolimus), for the proposed indication of prophylaxis of rejection in heart transplantation: report from the Cardiovascular and Renal Drugs Advisory Committee, US Food and Drug Administration, November 16, 2005, Rockville, Md.

Journal: Circulation 20060314

Title: Simultaneous determination of everolimus and cyclosporine concentrations by HPLC with ultraviolet detection.

Journal: Clinica chimica acta; international journal of clinical chemistry 20060201

Title: Revisiting late loss and neointimal volumetric measurements in a drug-eluting stent trial: analysis from the SPIRIT FIRST trial.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060201

Title: Everolimus versus azathioprine in maintenance lung transplant recipients: an international, randomized, double-blind clinical trial.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060101

Title: Pulsed immunosuppression with everolimus and anti-alphabeta T-cell receptor: laryngeal allograft preservation at six months.

Journal: The Annals of otology, rhinology, and laryngology 20060101

Title: Everolimus: a review of its use in renal and cardiac transplantation.

Journal: Drugs 20060101

Title: Role of FK778 alone or in combination with tacrolimus or mTOR inhibitors as an immunomodulator of immunofunctions: in vitro evaluation of T cell proliferation and the expression of lymphocyte surface antigens.

Journal: International journal of immunopathology and pharmacology 20060101

Title: Optimal dosing and duration of oral everolimus to inhibit in-stent neointimal growth in rabbit iliac arteries.

Journal: Cardiovascular revascularization medicine : including molecular interventions 20060101

Title: Mammalian target of rapamycin is a promising target for novel therapeutic strategy against cancer.

Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20060101

Title: Cyclosporine A, FK-506, 40-0-[2-hydroxyethyl]rapamycin and mycophenolate mofetil inhibit proliferation of human intrahepatic biliary epithelial cells in vitro.

Journal: World journal of gastroenterology 20051228

Title: In smooth muscle, FK506-binding protein modulates IP3 receptor-evoked Ca2+ release by mTOR and calcineurin.

Journal: Journal of cell science 20051201

Title: Mechanisms of everolimus-induced glomerulosclerosis after glomerular injury in the rat.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051201

Title: Technology Insight: an overview of research in drug-eluting stents.

Journal: Nature clinical practice. Cardiovascular medicine 20051201

Title: Everolimus (certican) in heart transplantation: optimizing renal function through minimizing cyclosporine exposure.

Journal: Transplantation proceedings 20051201

Title: Late acute cardiac allograft rejection: new therapeutic options?

Journal: Transplantation proceedings 20051201

Title: Biomarkers for toxicodynamic monitoring of immunosuppressants: NMR-based quantitative metabonomics of the blood.

Journal: Therapeutic drug monitoring 20051201

Title: Mammalian target of rapamycin as a therapeutic target in leukemia.

Journal: Current molecular medicine 20051101

Title: Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies.

Journal: Transplantation 20051015

Title: [Everolimus].

Journal: Deutsche medizinische Wochenschrift (1946) 20051007

Title: Combination of imatinib with rapamycin or RAD001 acts synergistically only in Bcr-Abl-positive cells with moderate resistance to imatinib.

Journal: Leukemia 20051001

Title: Compensatory PI3-kinase/Akt/mTor activation regulates imatinib resistance development.

Journal: Leukemia 20051001

Title: Three-year efficacy and safety results from a study of everolimus versus mycophenolate mofetil in de novo renal transplant patients.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051001

Title: The role of therapeutic monitoring of everolimus in solid organ transplantation.

Journal: Therapeutic drug monitoring 20051001

Title: Pharmacokinetic interaction between verapamil and everolimus in healthy subjects.

Journal: British journal of clinical pharmacology 20051001

Title: Tolerability of cyclosphosphamide and methotrexate induction immunosuppression in nonhuman primates.

Journal: Toxicology 20050915

Title: A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein {beta} and NF-{kappa}B activity in Hodgkin and anaplastic large cell lymphomas.

Journal: Blood 20050901

Title: Analysis of exposure-response relationship in everolimus-cyclosporine combination regimen.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901

Title: Therapeutic drug monitoring for everolimus in heart transplant recipients: flawed model or a model for future use?

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901

Title: Immune cells in a heterotopic lamb-to-pig bronchial xenograft model.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050901

Title: Simultaneous measurement of sirolimus and everolimus in whole blood by HPLC with ultraviolet detection.

Journal: Clinical chemistry 20050901

Title: Enhanced radiation damage of tumor vasculature by mTOR inhibitors.

Journal: Oncogene 20050818

Title: Everolimus treatment downregulates renocortical cyclooxygenase-2 expression in the rat kidney.

Journal: British journal of pharmacology 20050801

Title: RAD001 (everolimus) improves the efficacy of replicating adenoviruses that target colon cancer.

Journal: Cancer research 20050801

Title: Everolimus versus mycophenolate mofetil in the prevention of rejection in de novo renal transplant recipients: a 3-year randomized, multicenter, phase III study.

Journal: Transplantation 20050727

Title: Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050715

Title: Influence of everolimus on steady-state pharmacokinetics of cyclosporine in maintenance renal transplant patients.

Journal: Journal of clinical pharmacology 20050701

Title: Everolimus alters the bronchoalveolar lavage and endobronchial biopsy immunologic profile post-human lung transplantation.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050601

Title: Reduction in calcineurin inhibitor exposure and maintenance of effective immunosuppression: clinical experience with everolimus (Certican).

Journal: Transplantation 20050515

Title: Introducing everolimus (Certican) in organ transplantation: an overview of preclinical and early clinical developments.

Journal: Transplantation 20050515

Title: Concentration-controlled everolimus (Certican): combination with reduced dose calcineurin inhibitors.

Journal: Transplantation 20050515

Title: Clinical experience with everolimus (Certican): optimizing dose and tolerability.

Journal: Transplantation 20050515

Title: Clinical experience with everolimus (Certican) in elderly recipients: the 'old-for-old' concept.

Journal: Transplantation 20050515

Title: Clinical experience with everolimus (Certican) in young renal transplant recipients.

Journal: Transplantation 20050515

Title: Clinical experience with everolimus (Certican): a summary.

Journal: Transplantation 20050515

Title: Blood concentrations of everolimus are markedly increased by ketoconazole.

Journal: Journal of clinical pharmacology 20050501

Title: Replicating oncolytic virus therapeutics - Third International Meeting.

Journal: IDrugs : the investigational drugs journal 20050501

Title: Assessment of microvascular perfusion changes in a rat breast tumor model using SonoVue to monitor the effects of different anti-angiogenic therapies.

Journal: Academic radiology 20050501

Title: Immunosuppressive therapy with everolimus can be associated with potentially life-threatening lingual angioedema.

Journal: Transplantation 20050427

Title: Pharmacokinetics of the immunosuppressant everolimus in maintenance renal transplant patients.

Journal: European journal of medical research 20050420

Title: Adjusted indirect comparison of intracoronary drug-eluting stents: evidence from a metaanalysis of randomized bare-metal-stent-controlled trials.

Journal: International journal of cardiology 20050408

Title: Therapeutic drug monitoring for everolimus in kidney transplantation using 12-month exposure, efficacy, and safety data.

Journal: Clinical transplantation 20050401

Title: Certican (Everolimus) in heart transplantation: from clinical trial to clinical experience. Proceedings of a meeting, Vienna, Austria, September 9, 2004.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401

Title: From clinical trials to clinical practice: an overview of Certican (everolimus) in heart transplantation.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401

Title: Prevention of cardiac allograft vasculopathy with Certican (everolimus): the Stanford University experience within the Certican Phase III clinical trial.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401

Title: Recommendations for use of Certican (everolimus) after heart transplantation: results from a German and Austrian Consensus Conference.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401

Title: Clinical experience with Certican (everolimus) in de novo heart transplant patients at the Deutsches Herzzentrum Berlin.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401

Title: Clinical experience with Certican (everolimus) in maintenance heart transplant patients at the Medical University of Vienna.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401

Title: Validation of a practical liquid chomatography with ultraviolet detection method for quantification of whole-blood everolimus in a clinical TDM laboratory.

Journal: Therapeutic drug monitoring 20050401

Title: Graft function, cardiovascular risk factors, and sex hormones in renal transplant recipients on an immunosuppressive regimen of everolimus, reduced dose of cyclosporine, and basiliximab.

Journal: Transplantation proceedings 20050401

Title: The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation.

Journal: Cell 20050325

Title: Everolimus and basiliximab permit suppression by human CD4+CD25+ cells in vitro.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050301

Title: Effect of multiple-dose erythromycin on everolimus pharmacokinetics.

Journal: European journal of clinical pharmacology 20050301

Title: A randomized trial of steroid avoidance in renal transplant patients treated with everolimus and cyclosporine.

Journal: Transplantation proceedings 20050301

Title: High-performance liquid chromatography with ultraviolet detection for therapeutic drug monitoring of everolimus.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225

Title: Economic evaluation of everolimus vs. azathioprine at one year after de novo heart transplantation.

Journal: Clinical transplantation 20050201

Title: Use of everolimus-eluting stent with a bioresorbable polymer coating for treatment of recurrent in-stent restenosis.

Journal: The Journal of invasive cardiology 20050201

Title: Assessment of glomerular and tubular functions in renal transplant patients receiving cyclosporine A in combination with either sirolimus or everolimus.

Journal: Clinical nephrology 20050201

Title: Angiographic results of the first human experience with everolimus-eluting stents for the treatment of coronary lesions (the FUTURE I trial).

Journal: The American journal of cardiology 20050101

Title: Coping with rejection: immunosuppressants and organ transplantation.

Journal: Drug discovery today 20050101

Title: [New immunodepressant drugs for the prevention and control of kidney transplant rejection].

Journal: Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20050101

Title: Predominant inhibition of interleukin-6 synthesis in patient-specific endothelial cells by mTOR inhibitors below a concentration range where cell proliferation is affected and mitotic arrest takes place.

Journal: Transplantation proceedings 20050101

Title: Drug therapy in the heart transplant recipient: part II: immunosuppressive drugs.

Journal: Circulation 20041221

Title: Which parameter should be chosen as primary endpoint for randomized drug-eluting stent studies?

Journal: Journal of interventional cardiology 20041201

Title: Clinical experiences using everolimus-eluting stents in patients with coronary artery disease.

Journal: Journal of interventional cardiology 20041201

Title: Therapeutic drug monitoring for everolimus in heart transplant recipients based on exposure-effect modeling.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041201

Title: Pharmacokinetics of immunosuppressants: a perspective on ethnic differences.

Journal: International journal of clinical pharmacology and therapeutics 20041201

Title: [16th EORTC-NCI-AACR symposium on new molecular targets and cancer therapeutics].

Journal: Bulletin du cancer 20041201

Title: Everolimus (Certican) 12-month safety and efficacy versus mycophenolate mofetil in de novo renal transplant recipients.

Journal: Transplantation 20041127

Title: Everolimus and reduced-exposure cyclosporine in de novo renal-transplant recipients: a three-year phase II, randomized, multicenter, open-label study.

Journal: Transplantation 20041115

Title: Cyclooxygenase-2 expression in experimental post-transplant obliterative bronchiolitis.

Journal: The Journal of pathology 20041101

Title: Bcl-2 and CCND1/CDK4 expression levels predict the cellular effects of mTOR inhibitors in human ovarian carcinoma.

Journal: Apoptosis : an international journal on programmed cell death 20041101

Title: Everolimus suppresses cancellous bone loss, bone resorption, and cathepsin K expression by osteoclasts.

Journal: Bone 20041101

Title: Tolerability and steady-state pharmacokinetics of everolimus in maintenance renal transplant patients.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041001

Title: Alterations in glucose metabolism by cyclosporine in rat brain slices link to oxidative stress: interactions with mTOR inhibitors.

Journal: British journal of pharmacology 20041001

Title: Everolimus therapeutic concentration range defined from a prospective trial with reduced-exposure cyclosporine in de novo kidney transplantation.

Journal: Therapeutic drug monitoring 20041001

Title: [When are drug-eluting stents effective? A critical analysis of the presently available data].

Journal: Zeitschrift fur Kardiologie 20040901

Title: Drug-eluting stents: is it the beginning of the end for coronary artery bypass surgery?

Journal: Chinese medical journal 20040901

Title: Differential effects of everolimus and cyclosporine A on intimal alpha-actin-positive cell dynamics of carotid allografts in mice.

Journal: Transplantation 20040815

Title: Everolimus-induced drug fever after heart transplantation.

Journal: Transplantation 20040727

Title: New immunosuppressant class not without serious concerns.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040615

Title: mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.

Journal: Nature medicine 20040601

Title: TORward AKTually useful mouse models.

Journal: Nature medicine 20040601

Title: Chronic allograft nephropathy: pathogenesis and management of an important posttransplant complication.

Journal: Progress in transplantation (Aliso Viejo, Calif.) 20040601

Title: Future immunosuppressive agents in solid-organ transplantation.

Journal: Progress in transplantation (Aliso Viejo, Calif.) 20040601

Title: Six- and twelve-month results from first human experience using everolimus-eluting stents with bioabsorbable polymer.

Journal: Circulation 20040511

Title: How many grails do we need?

Journal: Circulation 20040511

Title: Everolimus stent proves effective.

Journal: Circulation 20040511

Title: Optimizing the immunosuppressive regimen in heart transplantation.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040501

Title: Economic evaluation of everolimus versus mycophenolate mofetil in combination with cyclosporine and prednisolone in de novo renal transplant recipients.

Journal: Transplant international : official journal of the European Society for Organ Transplantation 20040501

Title: ['Active' endoprosthesis with in situ release of an antimitotic or cytostatic drug: a revolution that cannot do without thought].

Journal: Annales de cardiologie et d'angeiologie 20040501

Title: Everolimus with optimized cyclosporine dosing in renal transplant recipients: 6-month safety and efficacy results of two randomized studies.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040401

Title: Islet allograft survival in nonhuman primates immunosuppressed with basiliximab, RAD, and FTY720.

Journal: Transplantation 20040327

Title: The evolving experience using everolimus in clinical transplantation.

Journal: Transplantation proceedings 20040301

Title: Experience with everolimus.

Journal: Transplantation proceedings 20040301

Title: The promise of C2, Simulect, and Certican in heart transplantation.

Journal: Transplantation proceedings 20040301

Title: Promise of Neoral C2, basiliximab, and everolimus in lung transplantation.

Journal: Transplantation proceedings 20040301

Title: Rapamycin analogs for stent-based local drug delivery. Everolimus- and tacrolimus-eluting stents.

Journal: Herz 20040301

Title: Cardiac allograft vasculopathy: advances in understanding its pathophysiology, prevention, and treatment.

Journal: Current opinion in cardiology 20040301

Title: Molecule of the month. Everolimus.

Journal: Drug news & perspectives 20040301

Title: Mammalian target of rapamycin inhibition as therapy for hematologic malignancies.

Journal: Cancer 20040215

Title: Is everolimus useful in preventing allograft rejection and vasculopathy after heart transplant?

Journal: Expert opinion on investigational drugs 20040201

Title: Everolimus: a proliferation signal inhibitor targeting primary causes of allograft dysfunction.

Journal: Drugs of today (Barcelona, Spain : 1998) 20040201

Title: Everolimus and mycophenolate mofetil are potent inhibitors of fibroblast proliferation after lung transplantation.

Journal: Transplantation 20040127

Title: Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells.

Journal: Cancer research 20040101

Title: Clinical pharmacokinetics of everolimus.

Journal: Clinical pharmacokinetics 20040101

Title: Everolimus/cyclosporine interactions on bile flow and biliary excretion of bile salts and cholesterol in rats.

Journal: Digestive diseases and sciences 20040101

Title: Everolimus.

Journal: Drugs 20040101

Title: New immunosuppressive strategies in renal transplant recipients.

Journal: Journal of nephrology 20040101

Title: Everolimus for stent-based intracoronary applications.

Journal: Reviews in cardiovascular medicine 20040101

Title: [Everolimus: immunosuppression with antilymphoproliferative therapy].

Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101

Title: The pleiotropic effects of mTor inhibitors.

Journal: Journal of nephrology 20040101

Title: Everolimus in cardiac-transplant recipients.

Journal: The New England journal of medicine 20031204

Title: Influence of delayed initiation of cyclosporine on everolimus pharmacokinetics in de novo renal transplant patients.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20031201

Title: Current immunosuppressive agents: efficacy, side effects, and utilization.

Journal: Pediatric clinics of North America 20031201

Title: Differential effect of cyclosporine A and SDZ RAD on neointima formation of carotid allografts in apolipoprotein E-deficient mice.

Journal: Transplantation 20031027

Title: Everolimus in de novo cardiac transplantation: pharmacokinetics, therapeutic range, and influence on cyclosporine exposure.

Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20031001

Title: Cardiac-allograft vasculopathy.

Journal: The New England journal of medicine 20030828

Title: Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.

Journal: The New England journal of medicine 20030828

Title: Apoptosis and treatment of chronic allograft nephropathy with everolimus.

Journal: Transplantation 20030815

Title: Survival of acute myeloid leukemia cells requires PI3 kinase activation.

Journal: Blood 20030801

Title: Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways.

Journal: The American journal of pathology 20030701

Title: The influence of the rapamycin-derivate SDZ RAD on the healing of airway anastomoses.

Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20030701

Title: Everolimus in pediatric de nova renal transplant patients.

Journal: Transplantation 20030627

Title: Influence of SDZ RAD vs. MMF on gastric emptying in renal transplant recipients.

Journal: Clinical transplantation 20030601

Title: Immunosuppressive TOR kinase inhibitor everolimus (RAD) suppresses growth of cells derived from posttransplant lymphoproliferative disorder at allograft-protecting doses.

Journal: Transplantation 20030527

Title: Pharmacokinetics of an everolimus-cyclosporine immunosuppressive regimen over the first 6 months after kidney transplantation.

Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030501

Title: Macrophage labeling by SPIO as an early marker of allograft chronic rejection in a rat model of kidney transplantation.

Journal: Magnetic resonance in medicine 20030301

Title: Clinical development of an everolimus pediatric formulation: relative bioavailability, food effect, and steady-state pharmacokinetics.

Journal: Journal of clinical pharmacology 20030201

Title: Synergistic effects of RAD and Neoral in inhibition of host-vs.-graft and graft-vs.-host immune responses in rat small-bowel transplantation.

Journal: Microsurgery 20030101

Title: Review of the proliferation inhibitor everolimus.

Journal: Expert opinion on investigational drugs 20021201

Title: Evaluation for synergistic suppression of T cell responses to minor histocompatibility antigens by chloroquine in combination with tacrolimus and a rapamycin derivative, SDZ-RAD.

Journal: Bone marrow transplantation 20021201

Title: Interaction of immunosuppressive agents rapamycin and its analogue SDZ-RAD with endothelial P-gp.

Journal: Transplantation proceedings 20021201

Title: [To further improve transplantation results].

Journal: Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20021201

Title: Therapeutic drug monitoring of immunosuppressive drugs in kidney transplantation.

Journal: Current opinion in nephrology and hypertension 20021101

Title: Systemic drug therapy for restenosis: 'déjà vu all over again'.

Journal: Circulation 20021029

Title: Oral everolimus inhibits in-stent neointimal growth.

Journal: Circulation 20021029

Title: Clinical development of mammalian target of rapamycin inhibitors.

Journal: Hematology/oncology clinics of North America 20021001

Title: Everolimus (Certican) in combination with neoral in pediatric renal transplant recipients: interim analysis after 3 months.

Journal: Transplantation proceedings 20020901

Title: Long-term pharmacokinetics of the metabolites of everolimus and cyclosporine in renal transplant recipients.

Journal: Transplantation proceedings 20020901

Title: Quantification and stability of everolimus (SDZ RAD) in human blood by high-performance liquid chromatography-electrospray tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020605

Title: Effect of rifampin on apparent clearance of everolimus.

Journal: The Annals of pharmacotherapy 20020601

Title: Rapid liquid chromatography-tandem mass spectrometry routine method for simultaneous determination of sirolimus, everolimus, tacrolimus, and cyclosporin A in whole blood.

Journal: Clinical chemistry 20020601

Title: Influence of a novel rapamycin analogon SDZ RAD on endothelial tissue factor and adhesion molecule expression.

Journal: Transplantation proceedings 20020601

Title: The rapamycin analogue SDZ RAD attenuates bleomycin-induced pulmonary fibrosis in rats.

Journal: The European respiratory journal 20020601

Title: Single-dose pharmacokinetics and tolerability of everolimus in stable pediatric renal transplant patients.

Journal: Pediatric transplantation 20020401

Title: Exposure-response relationships for everolimus in de novo kidney transplantation: defining a therapeutic range.

Journal: Transplantation 20020327

Title: The future role of target of rapamycin inhibitors in renal transplantation.

Journal: Current opinion in urology 20020301

Title: Simultaneous quantification of sirolimus, everolimus, tacrolimus and cyclosporine by liquid chromatography-mass spectrometry (LC-MS).

Journal: Clinical chemistry and laboratory medicine 20020301

Title: Early clinical experience with a novel rapamycin derivative.

Journal: Therapeutic drug monitoring 20020201

Title: Pharmacokinetic and pharmacodynamic assessments of HMG-CoA reductase inhibitors when coadministered with everolimus.

Journal: Journal of clinical pharmacology 20020201

Title: Effect of food on everolimus absorption: quantification in healthy subjects and a confirmatory screening in patients with renal transplants.

Journal: Pharmacotherapy 20020201

Title: Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic.

Journal: Current opinion in investigational drugs (London, England : 2000) 20020201

Title: Synergism of RAD and cyclosporin A in prevention of acute rat corneal allograft rejection.

Journal: Cornea 20020101

Title: Differential influence of two cyclosporine formulations on everolimus pharmacokinetics: a clinically relevant pharmacokinetic interaction.

Journal: Journal of clinical pharmacology 20020101

Title: Influence of hepatic impairment on everolimus pharmacokinetics: implications for dose adjustment.

Journal: Clinical pharmacology and therapeutics 20011101

Title: Safety and efficacy of TOR inhibitors in pediatric renal transplant recipients.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001

Title: Efficacy of SDZ RAD compared with CsA monotherapyand combined Rad/FTY720 treatment in a murine cardiac allotransplantation model.

Journal: Transplant immunology 20011001

Title: Fluvastatin in combination with rad significantly reduces graft vascular disease in rat cardiac allografts.

Journal: Transplantation 20010927

Title: Immune cells and immunosuppression in a porcine bronchial model of obliterative bronchiolitis.

Journal: Transplantation 20010927

Title: Population pharmacokinetics of everolimus in de novo renal transplant patients: impact of ethnicity and comedications.

Journal: Clinical pharmacology and therapeutics 20010901

Title: [Focus on Islets of Langerhans transplantation].

Journal: Presse medicale (Paris, France : 1983) 20010901

Title: [mTOR and FTY 720 inhibitors].

Journal: Presse medicale (Paris, France : 1983) 20010901

Title: [Immunosuppression, ongoing clinical trials].

Journal: Presse medicale (Paris, France : 1983) 20010901

Title: Everolimus. Novartis.

Journal: Current opinion in investigational drugs (London, England : 2000) 20010901

Title: Coexpression of CD4 and CD8alpha on rat T-cells in whole blood: a sensitive marker for monitoring T-cell immunosuppressive drugs.

Journal: Journal of immunological methods 20010801

Title: In vitro immunosuppressive activity of tacrolimus dihydrodiol precursors obtained by chemical oxidation and identification of a new metabolite of SDZ-RAD by electrospray and electrospray-linked scan mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20010801

Title: Sirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brain.

Journal: British journal of pharmacology 20010701

Title: The effect of different immunosuppressants on alloantigen dependent and independent factors involved in the development of chronic rejection in an animal model.

Journal: Annals of the Royal College of Surgeons of England 20010701

Title: Metabolism of sirolimus and its derivative everolimus by cytochrome P450 3A4: insights from docking, molecular dynamics, and quantum chemical calculations.

Journal: Journal of medicinal chemistry 20010607

Title: A high-capacity quantitative mouse model of drug-mediated immunosuppression based on rejection of an allogeneic subcutaneous tumor.

Journal: The Journal of pharmacology and experimental therapeutics 20010601

Title: mTOR inhibitors: an overview.

Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20010601

Title: RAD in de novo renal transplantation: comparison of three doses on the incidence and severity of acute rejection.

Journal: Transplantation 20010527

Title: RAD reduces compensatory renal graft hypertrophy in a rat model of chronic rejection.

Journal: Transplantation proceedings 20010501

Title: FTY-720 is efficacious in monkey kidney transplantation.

Journal: Transplantation proceedings 20010501

Title: 40-O-(2-hydroxyethyl)-rapamycin attenuates pulmonary arterial hypertension and neointimal formation in rats.

Journal: American journal of respiratory and critical care medicine 20010201

Title: Pharmacokinetics and tolerability of 40-0-[2-hydroxyethyl]rapamycin in de novo liver transplant recipients.

Journal: Transplantation 20010115

Title: Longitudinal assessment of everolimus in de novo renal transplant recipients over the first post-transplant year: pharmacokinetics, exposure-response relationships, and influence on cyclosporine.

Journal: Clinical pharmacology and therapeutics 20010101

Title: Comparison of the in vitro metabolism of the macrolide immunosuppressants sirolimus and RAD.

Journal: Transplantation proceedings 20010101

Title: Donor pretreatment of grafts from marginal donors improves long-term graft outcome.

Journal: Transplantation proceedings 20010101

Title: High-throughput semi-automated 96-well liquid/liquid extraction and liquid chromatography/mass spectrometric analysis of everolimus (RAD 001) and cyclosporin a (CsA) in whole blood.

Journal: Rapid communications in mass spectrometry : RCM 20010101

Title: The evolving role of tor inhibitors for individualizing posttransplant immunosuppression.

Journal: Transplantation proceedings 20010101

Title: The role of Certican (everolimus, rad) in the many pathways of chronic rejection.

Journal: Transplantation proceedings 20010101

Title: Effect of ERL080A, RAD, and Neoral on hamster-to-rat heart xenograft survival.

Journal: Transplantation proceedings 20010101

Title: A phase I study of a 4-week course of SDZ-RAD (RAD) quiescent cyclosporine-prednisone-treated renal transplant recipients.

Journal: Transplantation 19991027

Title: Chemical modification of rapamycin: the discovery of SDZ RAD.

Journal: Transplantation proceedings 19980801

Title: O'Reilly T, et al. Biomarker Development for the Clinical Activity of the mTOR Inhibitor Everolimus (RAD001): Processes,Limitations, and Further Proposals. Transl Oncol. 2010 Apr;3(2):65-79.

Title: Kawata T, et al. Dual inhibition of the mTORC1 and mTORC2 signaling pathways is a promising therapeutic target for adult T-cell leukemia. Cancer Sci. 2018 Jan;109(1):103-111.

Title: Lane HA, et al. mTOR inhibitor RAD001 (everolimus) has antiangiogenic/vascular properties distinct from a VEGFR tyrosine kinase inhibitor. Clin Cancer Res, 2009, 15(5), 1612-1622.

Title: Zhu Y, et al. Antitumor effect of the mTOR inhibitor Everolimus on human breast cancer stem cells in vitro and in vivo. Tumour Biol. 2012 Oct;33(5):1349-62.

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Tags:159351-69-6 Molecular Formula|159351-69-6 MDL|159351-69-6 SMILES|159351-69-6 Everolimus