Title: Autophagy plays a pro-survival role against methamphetamine-induced apoptosis in H9C2 cells.
Journal: Toxicology letters 20180915
Title: Effect of cyclosporine, tacrolimus and sirolimus on cellular senescence in renal epithelial cells.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20180401
Title: Inhibition of autophagy enhances Hydroquinone-induced TK6 cell death.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20170601
Title: Effect of exogenous TGF-β1 on the cadmium-induced nephrotoxicity by inhibiting apoptosis of proximal tubular cells through PI3K-AKT-mTOR signaling pathway.
Journal: Chemico-biological interactions 20170501
Title: Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia.
Journal: American journal of human genetics 20170302
Title: mTOR inhibition by rapamycin protects against deltamethrin-induced apoptosis in PC12 Cells.
Journal: Environmental toxicology 20170101
Title: Phosphoramide mustard induces autophagy markers and mTOR inhibition prevents follicle loss due to phosphoramide mustard exposure.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20170101
Title: CWF-145, a novel synthetic quinolone derivative exerts potent antimitotic activity against human prostate cancer: Rapamycin enhances antimitotic drug-induced apoptosis through the inhibition of Akt/mTOR pathway.
Journal: Chemico-biological interactions 20161225
Title: Basal autophagy protects cardiomyocytes from doxorubicin-induced toxicity.
Journal: Toxicology 20160831
Title: Knockdown of NogoA prevents MPP+‑induced neurotoxicity in PC12 cells via the mTOR/STAT3 signaling pathway.
Journal: Molecular medicine reports 20160201
Title: Impairment of the autophagic flux in astrocytes intoxicated by trimethyltin.
Journal: Neurotoxicology 20160101
Title: Cabozantinib versus Everolimus in Advanced Renal-Cell Carcinoma.
Journal: The New England journal of medicine 20151105
Title: The role of mTOR during cisplatin treatment in an in vitro and ex vivo model of cervical cancer.
Journal: Toxicology 20150901
Title: Cannabidiol, a Cannabis sativa constituent, inhibits cocaine-induced seizures in mice: Possible role of the mTOR pathway and reduction in glutamate release.
Journal: Neurotoxicology 20150901
Title: Activation of Autophagic Flux against Xenoestrogen Bisphenol-A-induced Hippocampal Neurodegeneration via AMP kinase (AMPK)/Mammalian Target of Rapamycin (mTOR) Pathways.
Journal: The Journal of biological chemistry 20150821
Title: The mechanism of synergistic effects of arsenic trioxide and rapamycin in acute myeloid leukemia cell lines lacking typical t(15;17) translocation.
Journal: International journal of hematology 20150701
Title: A comprehensively characterized large panel of head and neck cancer patient-derived xenografts identifies the mTOR inhibitor everolimus as potential new treatment option.
Journal: International journal of cancer 20150615
Title: Synergistic effect of JQ1 and rapamycin for treatment of human osteosarcoma.
Journal: International journal of cancer 20150501
Title: Key role of phosphodiesterase 4A (PDE4A) in autophagy triggered by yessotoxin.
Journal: Toxicology 20150302
Title: mTOR inhibition improves immune function in the elderly.
Journal: Science translational medicine 20141224
Title: The immunosuppressant tributyltin oxide blocks the mTOR pathway, like rapamycin, albeit by a different mechanism.
Journal: Journal of applied toxicology : JAT 20141201
Title: A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy.
Journal: Nature chemical biology 20141201
Title: The bromodomain and extra-terminal inhibitor CPI203 enhances the antiproliferative effects of rapamycin on human neuroendocrine tumors.
Journal: Cell death & disease 20141001
Title: P-glycoprotein, CYP3A, and plasma carboxylesterase determine brain and blood disposition of the mTOR Inhibitor everolimus (Afinitor) in mice.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20140615
Title: A phase Ib trial of LY2584702 tosylate, a p70 S6 inhibitor, in combination with erlotinib or everolimus in patients with solid tumours.
Journal: European journal of cancer (Oxford, England : 1990) 20140301
Title: Resveratrol prevents rapamycin-induced upregulation of autophagy and selectively induces apoptosis in TSC2-deficient cells.
Journal: Cell cycle (Georgetown, Tex.) 20140201
Title: Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency.
Journal: Nature immunology 20140101
Title: Conversion to sirolimus ameliorates cyclosporine-induced nephropathy in the rat: focus on serum, urine, gene, and protein renal expression biomarkers.
Journal: BioMed research international 20140101
Title: Rapamycin attenuated cardiac hypertrophy induced by isoproterenol and maintained energy homeostasis via inhibiting NF-κB activation.
Journal: Mediators of inflammation 20140101
Title: Autophagy maturation associated with CD38-mediated regulation of lysosome function in mouse glomerular podocytes.
Journal: Journal of cellular and molecular medicine 20131201
Title: Activation of autophagy rescues amiodarone-induced apoptosis of lung epithelial cells and pulmonary toxicity in rats.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131101
Title: PI3Kδ inhibition augments the efficacy of rapamycin in suppressing proliferation of Epstein-Barr virus (EBV)+ B cell lymphomas.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20130801
Title: Synergistic interactions between sorafenib and everolimus in pancreatic cancer xenografts in mice.
Journal: Cancer chemotherapy and pharmacology 20130501
Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Journal: The Biochemical journal 20130415
Title: Inhibition of rapamycin-induced Akt phosphorylation by cotylenin A correlates with their synergistic growth inhibition of cancer cells.
Journal: International journal of oncology 20130201
Title: Efficacy of RNA polymerase II inhibitors in targeting dormant leukaemia cells.
Journal: BMC pharmacology & toxicology 20130101
Title: Enhancement of autophagy by simvastatin through inhibition of Rac1-mTOR signaling pathway in coronary arterial myocytes.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20130101
Title: Arsenic trioxide overcomes rapamycin-induced feedback activation of AKT and ERK signaling to enhance the anti-tumor effects in breast cancer.
Journal: PloS one 20130101
Title: Involvement of autophagy in the pharmacological effects of the mTOR inhibitor everolimus in acute kidney injury.
Journal: European journal of pharmacology 20121205
Title: A phase I study of temozolomide and everolimus (RAD001) in patients with newly diagnosed and progressive glioblastoma either receiving or not receiving enzyme-inducing anticonvulsants: an NCIC CTG study.
Journal: Investigational new drugs 20121201
Title: A phase II trial of temsirolimus in second-line metastatic urothelial cancer.
Journal: Medical oncology (Northwood, London, England) 20121201
Title: Rapamycin treatment inhibits CHO cell death in a serum-free suspension culture by autophagy induction.
Journal: Biotechnology and bioengineering 20121201
Title: Autophagy is a cell self-protective mechanism against arsenic-induced cell transformation.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20121201
Title: The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cells.
Journal: Biochimie 20121201
Title: Acute and sustained effects of a metabotropic glutamate 5 receptor antagonist in the novelty-suppressed feeding test.
Journal: Behavioural brain research 20121201
Title: Enteric-delivered rapamycin enhances resistance of aged mice to pneumococcal pneumonia through reduced cellular senescence.
Journal: Experimental gerontology 20121201
Title: The expression of URGCP gene in prostate cancer cell lines: correlation with rapamycin.
Journal: Molecular biology reports 20121201
Title: Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signaling.
Journal: Aging 20121201
Title: Efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 in a preclinical model of adrenocortical carcinoma.
Journal: Molecular and cellular endocrinology 20121125
Title: Sirolimus solid self-microemulsifying pellets: formulation development, characterization and bioavailability evaluation.
Journal: International journal of pharmaceutics 20121115
Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Randomized comparison of the Nobori biolimus A9-eluting stent with the sirolimus-eluting stent in patients with stenosis in native coronary arteries.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20121101
Title: Phase II trial of temsirolimus in patients with metastatic breast cancer.
Journal: Breast cancer research and treatment 20121101
Title: Remarkable inhibition of mTOR signaling by the combination of rapamycin and 1,4-phenylenebis(methylene)selenocyanate in human prostate cancer cells.
Journal: International journal of cancer 20121101
Title: Influence of sirolimus-loaded nanoparticles on physiological functions of native human polymorphonuclear neutrophils.
Journal: Nanomedicine : nanotechnology, biology, and medicine 20121101
Title: Role of autophagy inhibitors and inducers in modulating the toxicity of trimethyltin in neuronal cell cultures.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20121101
Title: Rapamycin enhances dimethyl sulfoxide-mediated growth arrest in human myelogenous leukemia cells.
Journal: Leukemia & lymphoma 20121101
Title: Acetylation of histone H3 prevents resistance development caused by chronic mTOR inhibition in renal cell carcinoma cells.
Journal: Cancer letters 20121101
Title: Assessment of an asymmetrical coating stent with sirolimus released from ablumial matrix in porcine model.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20121101
Title: Anti-thymocyte globulin (thymoglobulin), tacrolimus, and sirolimus as acute graft-versus-host disease prophylaxis for unrelated hematopoietic stem cell transplantation.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20121101
Title: Rapamycin-mediated suppression of renal cyst expansion in del34 Pkd1-/- mutant mouse embryos: an investigation of the feasibility of renal cyst prevention in the foetus.
Journal: Nephrology (Carlton, Vic.) 20121101
Title: UV-visible spectroscopy as an alternative to liquid chromatography for determination of everolimus in surfactant-containing dissolution media: a useful approach based on solid-phase extraction.
Journal: Journal of pharmaceutical and biomedical analysis 20121101
Title: Proliferation signal inhibitors in the treatment of lupus nephritis: preliminary experience.
Journal: Nephrology (Carlton, Vic.) 20121101
Title: Pharmacological targeting of mammalian target of rapamycin inhibits ovarian granulosa cell tumor growth.
Journal: Carcinogenesis 20121101
Title: Autophagy-dependent and -independent involvement of AMP-activated protein kinase in 6-hydroxydopamine toxicity to SH-SY5Y neuroblastoma cells.
Journal: Biochimica et biophysica acta 20121101
Title: A dose escalation trial for the combination of erlotinib and sirolimus for recurrent malignant gliomas.
Journal: Journal of neuro-oncology 20121101
Title: NVP-BEZ235 alone and in combination in mantle cell lymphoma: an effective therapeutic strategy.
Journal: Expert opinion on investigational drugs 20121101
Title: Autophagy modulators sensitize prostate epithelial cancer cell lines to TNF-alpha-dependent apoptosis.
Journal: Apoptosis : an international journal on programmed cell death 20121101
Title: Towards excellence in revascularization for left main coronary artery disease.
Journal: Current opinion in cardiology 20121101
Title: Everolimus synergizes with gefitinib in non-small-cell lung cancer cell lines resistant to epidermal growth factor receptor tyrosine kinase inhibitors.
Journal: Cancer chemotherapy and pharmacology 20121101
Title: A drug safety evaluation of everolimus in kidney transplantation.
Journal: Expert opinion on drug safety 20121101
Title: Endothelial progenitor cell response to antiproliferative drug exposure.
Journal: Atherosclerosis 20121101
Title: Phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway inhibition: a breakthrough in the management of luminal (ER+/HER2-) breast cancers?
Journal: Current opinion in oncology 20121101
Title: Prolonged response using gefitinib followed by sirolimus for advanced cutaneous squamous cell carcinoma.
Journal: Journal of the American Academy of Dermatology 20121101
Title: Topical sirolimus for oral pemphigus vulgaris: 3 unresponsive cases.
Journal: Journal of the American Academy of Dermatology 20121101
Title: Hemodialysis does not affect everolimus pharmacokinetics: two cases of patients with metastatic renal cell cancer.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20121101
Title: Bioanalytical method validation of rapamycin in ocular matrix by QTRAP LC-MS/MS: application to rabbit anterior tissue distribution by topical administration of rapamycin nanomicellar formulation.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20121101
Title: Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice.
Journal: Neuroscience 20121025
Title: Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia.
Journal: Blood 20121025
Title: Mammalian target of rapamycin signaling is a key regulator of the transit-amplifying progenitor pool in the adult and aging forebrain.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20121024
Title: Stent thrombosis and major clinical events at 3 years after zotarolimus-eluting or sirolimus-eluting coronary stent implantation: a randomised, multicentre, open-label, controlled trial.
Journal: Lancet (London, England) 20121020
Title: Sirolimus and skin-cancer prevention in kidney transplantation.
Journal: The New England journal of medicine 20121018
Title: Clinical and histopathologic characteristics of rash in cancer patients treated with mammalian target of rapamycin inhibitors.
Journal: Cancer 20121015
Title: Phase I study of the antiangiogenic antibody bevacizumab and the mTOR/hypoxia-inducible factor inhibitor temsirolimus combined with liposomal doxorubicin: tolerance and biological activity.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20121015
Title: A comprehensive review of everolimus clinical reports: a new mammalian target of rapamycin inhibitor.
Journal: Transplantation 20121015
Title: Genome sequencing identifies a basis for everolimus sensitivity.
Journal: Science (New York, N.Y.) 20121012
Title: Mammalian target of rapamycin regulates neutrophil extracellular trap formation via induction of hypoxia-inducible factor 1 α.
Journal: Blood 20121011
Title: Pharmacokinetic study of 3-in-1 poly(ethylene glycol)-block-poly(D, L-lactic acid) micelles carrying paclitaxel, 17-allylamino-17-demethoxygeldanamycin, and rapamycin.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20121010
Title: A new strategy for discontinuation of dual antiplatelet therapy: the RESET Trial (REal Safety and Efficacy of 3-month dual antiplatelet Therapy following Endeavor zotarolimus-eluting stent implantation).
Journal: Journal of the American College of Cardiology 20121009
Title: Prevention of alveolar destruction and airspace enlargement in a mouse model of pulmonary lymphangioleiomyomatosis (LAM).
Journal: Science translational medicine 20121003
Title: Sustained clinical effectiveness and favorable safety profile of topical sirolimus for tuberous sclerosis - associated facial angiofibroma.
Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20121001
Title: Phase I study of temsirolimus in combination with EKB-569 in patients with advanced solid tumors.
Journal: Investigational new drugs 20121001
Title: Sirolimus- versus paclitaxel-eluting stents for coronary bifurcations intervention: a meta-analysis of five clinical trials.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20121001
Title: The XIENCE nano everolimus eluting coronary stent system for the treatment of small coronary arteries: the SPIRIT Small Vessel trial.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20121001
Title: Rapamycin blocks hepatoblastoma growth in vitro and in vivo implicating new treatment options in high-risk patients.
Journal: European journal of cancer (Oxford, England : 1990) 20121001
Title: The impact of prophylactic antiviral agents and statin administration on graft longevity in kidney allograft recipients.
Journal: Immunopharmacology and immunotoxicology 20121001
Title: Phase II study of everolimus in patients with locally advanced or metastatic transitional cell carcinoma of the urothelial tract: clinical activity, molecular response, and biomarkers.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20121001
Title: Effects of FTY720 and rapamycin on inflammation in taurocholate-induced acute pancreatitis in the rat.
Journal: Pancreas 20121001
Title: Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones.
Journal: Cancer letters 20121001
Title: Antitumor effect of the mTOR inhibitor everolimus in combination with trastuzumab on human breast cancer stem cells in vitro and in vivo.
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20121001
Title: Neoadjuvant therapy of renal cell carcinoma: a novel treatment option in the era of targeted therapy?
Journal: International journal of urology : official journal of the Japanese Urological Association 20121001
Title: Tolerability and pharmacokinetics of intravitreal sirolimus.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20121001
Title: Novel agents in Hodgkin lymphoma.
Journal: Current oncology reports 20121001
Title: NEX-TRAP, a novel method for in vivo analysis of nuclear export of proteins.
Journal: Traffic (Copenhagen, Denmark) 20121001
Title: Combined blockade of signalling pathways shows marked anti-tumour potential in phaeochromocytoma cell lines.
Journal: Journal of molecular endocrinology 20121001
Title: Phase I study of pasireotide (SOM 230) and everolimus (RAD001) in advanced neuroendocrine tumors.
Journal: Endocrine-related cancer 20121001
Title: Impact of the first-generation drug-eluting stent implantation on periprocedural myocardial injury in patients with stable angina pectoris.
Journal: Journal of cardiology 20121001
Title: Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide-cGMP and PI3K/mTOR pathways.
Journal: Behavioural brain research 20121001
Title: Macroautophagy can press a brake on presynaptic neurotransmission.
Journal: Autophagy 20121001
Title: Ischemic postconditioning during reperfusion attenuates intestinal injury and mucosal cell apoptosis by inhibiting JAK/STAT signaling activation.
Journal: Shock (Augusta, Ga.) 20121001
Title: Effects of sotrastaurin, mycophenolic acid and everolimus on human B-lymphocyte function and activation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20121001
Title: Serial change and its determinants of residual plaque characteristics under sirolimus-eluting stent: a coronary angioscopic study.
Journal: Journal of cardiology 20121001
Title: Luteinizing hormone/human chorionic gonadotropin-mediated activation of mTORC1 signaling is required for androgen synthesis by theca-interstitial cells.
Journal: Molecular endocrinology (Baltimore, Md.) 20121001
Title: Disrupting the mTOR signaling network as a potential strategy for the enhancement of cancer radiotherapy.
Journal: Current cancer drug targets 20121001
Title: IL-22 induced cell proliferation is regulated by PI3K/Akt/mTOR signaling cascade.
Journal: Cytokine 20121001
Title: Everolimus for advanced pancreatic neuroendocrine tumours: a subgroup analysis evaluating Japanese patients in the RADIANT-3 trial.
Journal: Japanese journal of clinical oncology 20121001
Title: Association of sirolimus adverse effects with m-TOR, p70S6K or Raptor polymorphisms in kidney transplant recipients.
Journal: Pharmacogenetics and genomics 20121001
Title: Everolimus for the treatment of pancreatic neuroendocrine tumors.
Journal: Expert opinion on pharmacotherapy 20121001
Title: FLT-PET is superior to FDG-PET for very early response prediction in NPM-ALK-positive lymphoma treated with targeted therapy.
Journal: Cancer research 20121001
Title: Hypoxia induces autophagy in primary human trophoblasts.
Journal: Endocrinology 20121001
Title: A single supratherapeutic dose of ridaforolimus does not prolong the QTc interval in patients with advanced cancer.
Journal: Cancer chemotherapy and pharmacology 20121001
Title: A phase I study of erlotinib and hydroxychloroquine in advanced non-small-cell lung cancer.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20121001
Title: Counteracting autophagy overcomes resistance to everolimus in mantle cell lymphoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20121001
Title: Everolimus in pediatric transplantation.
Journal: Current opinion in organ transplantation 20121001
Title: Antitumor activity of Triolimus: a novel multidrug-loaded micelle containing Paclitaxel, Rapamycin, and 17-AAG.
Journal: Molecular cancer therapeutics 20121001
Title: Analysis of cyclosporin A, tacrolimus, sirolimus, and everolimus in dried blood spot samples using liquid chromatography tandem mass spectrometry.
Journal: Analytical and bioanalytical chemistry 20121001
Title: Targeting androgen receptor leads to suppression of prostate cancer via induction of autophagy.
Journal: The Journal of urology 20121001
Title: Preventive and therapeutic effects of rapamycin, a mammalian target of rapamycin inhibitor, on food allergy in mice.
Journal: Allergy 20121001
Title: Arsenic trioxide synergizes with everolimus (Rad001) to induce cytotoxicity of ovarian cancer cells through increased autophagy and apoptosis.
Journal: Endocrine-related cancer 20121001
Title: An evaluation of sirolimus in renal transplantation.
Journal: Expert opinion on drug metabolism & toxicology 20121001
Title: Everolimus and erlotinib as second- or third-line therapy in patients with advanced non-small-cell lung cancer.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20121001
Title: Target of rapamycin (TOR) controls vitellogenesis via activation of the S6 kinase in the fat body of the tick, Haemaphysalis longicornis.
Journal: International journal for parasitology 20121001
Title: Successful sirolimus graded dose challenge in an erythromycin-allergic patient.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20121001
Title: Sirolimus in renal transplantation: analysis of safety and efficacy in a nonprotocol conversion group.
Journal: Transplantation proceedings 20121001
Title: Sirolimus as rescue therapy after liver transplantation.
Journal: Transplantation proceedings 20121001
Title: Pain syndrome induced by calcineurin inhibitor and resolved by conversion to sirolimus in a child after kidney transplantation: a case report.
Journal: Transplantation proceedings 20121001
Title: Topical use of rapamycin in herpetic stromal keratitis.
Journal: Ocular immunology and inflammation 20121001
Title: Comparison of twelve-month outcomes after percutanous coronary intervention with everolimus-eluting versus zotarolimus-eluting or sirolimus-eluting stents from the PROENCY (PROmus ENdeavor CYpher) registry.
Journal: The Journal of invasive cardiology 20121001
Title: Late stent thrombosis of a second-generation drug- eluting stent.
Journal: The Journal of invasive cardiology 20121001
Title: Comparison of paclitaxal vs. sirolimus eluting stents with bio-degradable polymer for the treatment of coronary bifurcation lesions: subgroup analysis from DKCRUSH-I and DKCRUSH-II studies.
Journal: Chinese medical journal 20121001
Title: Vascular healing in drug-eluting stents: differential drug-associated response of limus-eluting stents in a preclinical model of stent implantation.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20121001
Title: Enhanced drug delivery capabilities from stents coated with absorbable polymer and crystalline drug.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20120928
Title: Folate-conjugated rapamycin slows progression of polycystic kidney disease.
Journal: Journal of the American Society of Nephrology : JASN 20120928
Title: Tuberin inhibits production of the matrix protein fibronectin in diabetes.
Journal: Journal of the American Society of Nephrology : JASN 20120928
Title: Targeting of mTORC1/2 by the mTOR kinase inhibitor PP242 induces apoptosis in AML cells under conditions mimicking the bone marrow microenvironment.
Journal: Blood 20120927
Title: Wound healing complications and the use of mammalian target of rapamycin inhibitors in kidney transplantation: a critical review of the literature.
Journal: Transplantation 20120927
Title: An elaborate regulation of Mammalian target of rapamycin activity is required for somatic cell reprogramming induced by defined transcription factors.
Journal: Stem cells and development 20120920
Title: Serum lactate dehydrogenase predicts for overall survival benefit in patients with metastatic renal cell carcinoma treated with inhibition of mammalian target of rapamycin.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120920
Title: Rapamycin impairs UV induction of mutant-p53 overexpressing cell clusters without affecting tumor onset.
Journal: International journal of cancer 20120915
Title: Co-administration strategy to enhance brain accumulation of vandetanib by modulating P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp1/Abcg2) mediated efflux with m-TOR inhibitors.
Journal: International journal of pharmaceutics 20120915
Title: Cost-effectiveness of everolimus- versus paclitaxel-eluting stents for patients undergoing percutaneous coronary revascularization (from the SPIRIT-IV Trial).
Journal: The American journal of cardiology 20120915
Title: Immunomodulatory synergy by combining atorvastatin and rapamycin in the treatment of experimental autoimmune encephalomyelitis (EAE).
Journal: Journal of neuroimmunology 20120915
Title: Human TSC-associated renal angiomyolipoma cells are hypersensitive to ER stress.
Journal: American journal of physiology. Renal physiology 20120915
Title: Leptin-induced mTOR activation defines a specific molecular and transcriptional signature controlling CD4+ effector T cell responses.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20120915
Title: Heme oxygenase-1 promotes survival of renal cancer cells through modulation of apoptosis- and autophagy-regulating molecules.
Journal: The Journal of biological chemistry 20120914
Title: mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis.
Journal: Cell stem cell 20120907
Title: Rapamycin down-regulates KCC2 expression and increases seizure susceptibility to convulsants in immature rats.
Journal: Neuroscience 20120906
Title: A neurotrophic hypothesis of depression: role of synaptogenesis in the actions of NMDA receptor antagonists.
Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20120905
Title: Rapamycin delays disease onset and prevents PrP plaque deposition in a mouse model of Gerstmann-Sträussler-Scheinker disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120905
Title: Antileukaemia effect of rapamycin alone or in combination with daunorubicin on Ph+ acute lymphoblastic leukaemia cell line.
Journal: Hematological oncology 20120901
Title: Central pontine myelinolysis: a case report and clinical-pathological review.
Journal: Pediatric transplantation 20120901
Title: Castleman disease in a pediatric liver transplant recipient: a case report and literature review.
Journal: Pediatric transplantation 20120901
Title: Successful sirolimus rescue in tacrolimus-induced thrombotic microangiopathy after living-related liver transplantation.
Journal: Pediatric transplantation 20120901
Title: In vivo comparison of a polymer-free Biolimus A9-eluting stent with a biodegradable polymer-based Biolimus A9 eluting stent and a bare metal stent in balloon denuded and radiated hypercholesterolemic rabbit iliac arteries.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120901
Title: Randomized comparison of cost-saving and effectiveness of oral rapamycin plus bare-metal stents with drug-eluting stents: three-year outcome from the randomized oral rapamycin in Argentina (ORAR) III trial.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120901
Title: Sirolimus - moving toward the mainstream in pediatric heart transplantation?
Journal: Pediatric transplantation 20120901
Title: K-Ras mutation-mediated IGF-1-induced feedback ERK activation contributes to the rapalog resistance in pancreatic ductal adenocarcinomas.
Journal: Cancer letters 20120901
Title: Enduring response to everolimus as third-line therapy in a patient with advanced renal cell carcinoma, including small-bowel metastases: loss of FHIT but normal VHL gene status.
Journal: Clinical genitourinary cancer 20120901
Title: Repetitive angioscopic observations of a sirolimus-eluting stent deployed in a patient with silent chronic thrombotic occlusion.
Journal: Cardiovascular intervention and therapeutics 20120901
Title: The development of novel biodegradable bifurcation stents for the sustainable release of anti-proliferative sirolimus.
Journal: Annals of biomedical engineering 20120901
Title: Indications for an alternative effective treatment of head and neck squamous cell carcinoma with temsirolimus plus bevacizumab: from bench to bedside?
Journal: Anti-cancer drugs 20120901
Title: Post-transplantation encapsulating peritoneal sclerosis in a pediatric patient.
Journal: Pediatric nephrology (Berlin, Germany) 20120901
Title: The novel combination of sirolimus and bortezomib prevents graft-versus-host disease but maintains the graft-versus-leukemia effect after allogeneic transplantation.
Journal: Haematologica 20120901
Title: Conversion to sirolimus in pediatric renal transplant patients: a single-center experience.
Journal: Pediatric transplantation 20120901
Title: Safety of posaconazole and sirolimus coadministration in allogeneic hematopoietic stem cell transplants.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120901
Title: Characterization of Foxp3 gene from grass carp (Ctenopharyngodon idellus): a rapamycin-inducible transcription factor in teleost immune system.
Journal: Developmental and comparative immunology 20120901
Title: Role of Toll-like receptor 2 in the immune response against hepadnaviral infection.
Journal: Journal of hepatology 20120901
Title: Case of complete response to everolimus for metastatic renal cell carcinoma.
Journal: International journal of urology : official journal of the Japanese Urological Association 20120901
Title: The long-term efficacy of cilostazol in addition to dual antiplatelet therapy after sirolimus-eluting stent implantation for Japanese patients: an analysis of the 3-year follow-up outcomes from the j-Cypher registry.
Journal: Cardiovascular intervention and therapeutics 20120901
Title: Sirolimus: more cause for alarm?
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120901
Title: Impact of sirolimus and tacrolimus on mortality and graft loss in liver transplant recipients with or without hepatitis C virus: an analysis of the Scientific Registry of Transplant Recipients Database.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120901
Title: Reduced intensity allogeneic hematopoietic stem cell transplantation for MDS using tacrolimus/sirolimus-based GVHD prophylaxis.
Journal: Leukemia research 20120901
Title: Sorafenib enhances the therapeutic efficacy of rapamycin in colorectal cancers harboring oncogenic KRAS and PIK3CA.
Journal: Carcinogenesis 20120901
Title: Contractile activity-induced mitochondrial biogenesis and mTORC1.
Journal: American journal of physiology. Cell physiology 20120901
Title: Efficacy of everolimus, a novel mTOR inhibitor, against basal-like triple-negative breast cancer cells.
Journal: Cancer science 20120901
Title: Rapamycin induces p53-independent apoptosis through the mitochondrial pathway in non-small cell lung cancer cells.
Journal: Oncology reports 20120901
Title: Rapamycin/IL-2 combination therapy in patients with type 1 diabetes augments Tregs yet transiently impairs β-cell function.
Journal: Diabetes 20120901
Title: Cap-dependent mRNA translation and the ubiquitin-proteasome system cooperate to promote ERBB2-dependent esophageal cancer phenotype.
Journal: Cancer gene therapy 20120901
Title: Development of a lymphangioleiomyomatosis model by endonasal administration of human TSC2-/- smooth muscle cells in mice.
Journal: The American journal of pathology 20120901
Title: Randomized controlled trial of sirolimus conversion in cardiac transplant recipients with renal insufficiency.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120901
Title: Rapamycin for treatment of type I autosomal dominant polycystic kidney disease (RAPYD-study): a randomized, controlled study.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120901
Title: PDGF receptor alpha is an alternative mediator of rapamycin-induced Akt activation: implications for combination targeted therapy of synovial sarcoma.
Journal: Cancer research 20120901
Title: Effect of immunosuppressive drugs on spontaneous DNA repair in human peripheral blood mononuclear cells.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20120901
Title: Does everolimus increase donor-specific HLA antibodies in kidney transplant recipients?
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120901
Title: Dual targeting of the Akt/mTOR signaling pathway inhibits castration-resistant prostate cancer in a genetically engineered mouse model.
Journal: Cancer research 20120901
Title: Dual targeting of mTOR and aurora-A kinase for the treatment of uterine Leiomyosarcoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120901
Title: Perifosine enhances mTORC1-targeted cancer therapy by activation of GSK3β in NSCLC cells.
Journal: Cancer biology & therapy 20120901
Title: Serum and glucocorticoid-regulated kinase 1 (SGK1) activation in breast cancer: requirement for mTORC1 activity associates with ER-alpha expression.
Journal: Breast cancer research and treatment 20120901
Title: Phase II study of the safety and efficacy of temsirolimus in East Asian patients with advanced renal cell carcinoma.
Journal: Japanese journal of clinical oncology 20120901
Title: Temsirolimus: a safety and efficacy review.
Journal: Expert opinion on drug safety 20120901
Title: Phase I studies of sirolimus alone or in combination with pharmacokinetic modulators in advanced cancer patients.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120901
Title: ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells.
Journal: Autophagy 20120901
Title: Inhibition of mTOR in carcinoid tumors.
Journal: Targeted oncology 20120901
Title: A novel image-based cytometry method for autophagy detection in living cells.
Journal: Autophagy 20120901
Title: The role of mTOR signaling pathway in spinal cord injury.
Journal: Cell cycle (Georgetown, Tex.) 20120901
Title: Incidence and risk of pulmonary toxicity in patients treated with mTOR inhibitors for malignancy. A meta-analysis of published trials.
Journal: Acta oncologica (Stockholm, Sweden) 20120901
Title: Renal angiomyolipomatosis and Kaposi's sarcoma: a possible link disrupted by sirolimus.
Journal: Internal and emergency medicine 20120901
Title: Resistance to targeted therapies in pancreatic neuroendocrine tumors (PNETs): molecular basis, preclinical data, and counteracting strategies.
Journal: Targeted oncology 20120901
Title: Immunotherapy in type 1 diabetes: a shorter but more winding road?
Journal: Diabetes 20120901
Title: Topical rapamycin therapy to alleviate the cutaneous manifestations of tuberous sclerosis complex: a double-blind, randomized, controlled trial to evaluate the safety and efficacy of topically applied rapamycin.
Journal: Drugs in R&D 20120901
Title: Everolimus: a new treatment option for advanced pancreatic neuroendocrine tumors.
Journal: The Annals of pharmacotherapy 20120901
Title: Conversion from calcineurin inhibitors to everolimus with low-dose cyclosporine in renal transplant recipients with squamous cell carcinoma of the skin.
Journal: Transplantation proceedings 20120901
Title: Everolimus and enteric-coated mycophenolate sodium ab initio after liver transplantation: midterm results.
Journal: Transplantation proceedings 20120901
Title: Caffeine induces apoptosis of osteosarcoma cells by inhibiting AKT/mTOR/S6K, NF-κB and MAPK pathways.
Journal: Anticancer research 20120901
Title: Comparative evaluation of small-molecule chemosensitizers in reversal of cisplatin resistance in ovarian cancer cells.
Journal: Anticancer research 20120901
Title: Long-term vascular healing in response to sirolimus- and paclitaxel-eluting stents: an optical coherence tomography study.
Journal: JACC. Cardiovascular interventions 20120901
Title: [Treatment of pulmonary and retroperitoneal lymphangioleiomyomatosis with rapamycin: a case presentation and literature review].
Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20120901
Title: Drug choices in autoimmune hepatitis: part B--Nonsteroids.
Journal: Expert review of gastroenterology & hepatology 20120901
Title: Emerging agents for the treatment of mantle cell lymphoma.
Journal: Expert review of anticancer therapy 20120901
Title: Clinical trial end points for assessing efficacy of novel therapies for soft-tissue sarcomas.
Journal: Expert review of anticancer therapy 20120901
Title: Intranasal rapamycin rescues mice from staphylococcal enterotoxin B-induced shock.
Journal: Toxins 20120901
Title: Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice.
Journal: Nature 20120830
Title: Effectiveness of a combination therapy using calcineurin inhibitor and mTOR inhibitor in preventing allograft rejection and post-transplantation renal cancer progression.
Journal: Cancer letters 20120828
Title: Constitutive activation of the mTOR signaling pathway within the normal glomerulus.
Journal: Biochemical and biophysical research communications 20120824
Title: Effect of biolimus-eluting stents with biodegradable polymer vs bare-metal stents on cardiovascular events among patients with acute myocardial infarction: the COMFORTABLE AMI randomized trial.
Journal: JAMA 20120822
Title: New-generation drug-eluting stents for patients with myocardial infarction.
Journal: JAMA 20120822
Title: Resistance to the mTOR-inhibitor RAD001 elevates integrin α2- and β1-triggered motility, migration and invasion of prostate cancer cells.
Journal: British journal of cancer 20120821
Title: Metabotropic actions of the volatile anaesthetic sevoflurane increase protein kinase M synthesis and induce immediate preconditioning protection of rat hippocampal slices.
Journal: The Journal of physiology 20120815
Title: Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan.
Journal: American journal of physiology. Endocrinology and metabolism 20120815
Title: The mTOR-inhibitor rapamycin mediates proteinuria in nephrotoxic serum nephritis by activating the innate immune response.
Journal: American journal of physiology. Renal physiology 20120815
Title: Multiple roles for mammalian target of rapamycin signaling in both glutamatergic and GABAergic synaptic transmission.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120815
Title: Resolution of chylous pulmonary congestion and respiratory failure in lymphangioleiomyomatosis with sirolimus therapy.
Journal: American journal of respiratory and critical care medicine 20120815
Title: Sirolimus-eluting stents for treatment of infrapopliteal arteries reduce clinical event rate compared to bare-metal stents: long-term results from a randomized trial.
Journal: Journal of the American College of Cardiology 20120814
Title: Stent elution rate determines drug deposition and receptor-mediated effects.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20120810
Title: Efficacy of rapamycin for refractory hemangioendotheliomas in Maffucci's syndrome.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120810
Title: Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons.
Journal: Neuron 20120809
Title: The Cdc48 protein and its cofactor Vms1 are involved in Cdc13 protein degradation.
Journal: The Journal of biological chemistry 20120803
Title: Sirolimus and everolimus intestinal absorption and interaction with calcineurin inhibitors: a differential effect between cyclosporine and tacrolimus.
Journal: Fundamental & clinical pharmacology 20120801
Title: Dietary restriction but not rapamycin extends disease onset and survival of the H46R/H48Q mouse model of ALS.
Journal: Neurobiology of aging 20120801
Title: Unprotected left main coronary artery stenting with zotarolimus (Endeavor) drug-eluting stents: a single center retrospective experience.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120801
Title: Phase I and pharmacokinetic study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced solid malignancies.
Journal: Investigational new drugs 20120801
Title: A role for maintenance therapy in managing sarcoma.
Journal: Cancer treatment reviews 20120801
Title: Optical coherence tomographic comparison of neointimal coverage between sirolimus- and resolute zotarolimus-eluting stents at 9 months after stent implantation.
Journal: The international journal of cardiovascular imaging 20120801
Title: Analysis of 1 year virtual histology changes in coronary plaque located behind the struts of the everolimus eluting bioresorbable vascular scaffold.
Journal: The international journal of cardiovascular imaging 20120801
Title: Frequency and impact of bleeding in elective coronary stent clinical trials--utility of three commonly used definitions.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120801
Title: Rapamycin inhibits transforming growth factor β-induced peritoneal angiogenesis by blocking the secondary hypoxic response.
Journal: Journal of cellular and molecular medicine 20120801
Title: PKI-587 and sorafenib targeting PI3K/AKT/mTOR and Ras/Raf/MAPK pathways synergistically inhibit HCC cell proliferation.
Journal: The Journal of surgical research 20120801
Title: Rapamycin induced ultrastructural and molecular alterations in glomerular podocytes in healthy mice.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120801
Title: Rapamycin induces heme oxygenase-1 in liver but inhibits bile flow recovery after ischemia.
Journal: The Journal of surgical research 20120801
Title: Mao-B elevation decreases parkin's ability to efficiently clear damaged mitochondria: protective effects of rapamycin.
Journal: Free radical research 20120801
Title: Treatment of coronary bifurcation lesions with drug-eluting stents: insights from the first phase of the prospective multicenter german drug-eluting stent registry.
Journal: Journal of interventional cardiology 20120801
Title: Rapamycin inhibits the invasive ability of thyroid cancer cells by down-regulating the expression of VEGF-C in vitro.
Journal: Cell biochemistry and function 20120801
Title: Low-dose rapamycin treatment increases the ability of human regulatory T cells to inhibit transplant arteriosclerosis in vivo.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120801
Title: Connective tissue growth factor (CTGF/CCN2): a protagonist in cardiac allograft vasculopathy development?
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120801
Title: The inhibitory effect of rapamycin on the oval cell response and development of preneoplastic foci in the rat.
Journal: Experimental and molecular pathology 20120801
Title: Combined use of rapamycin and leflunomide in prevention of acute cardiac allografts rejection in rats.
Journal: Transplant immunology 20120801
Title: Comparative assessment of transient exposure of paclitaxel or zotarolimus on in vitro vascular cell death, proliferation, migration, and proinflammatory biomarker expression.
Journal: Journal of cardiovascular pharmacology 20120801
Title: Autophagy sustains the replication of porcine reproductive and respiratory virus in host cells.
Journal: Virology 20120801
Title: Randomized phase II trial of everolimus in combination with tamoxifen in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer with prior exposure to aromatase inhibitors: a GINECO study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120801
Title: Sirolimus modulates HIVAN phenotype through inhibition of epithelial mesenchymal transition.
Journal: Experimental and molecular pathology 20120801
Title: Rapamycin slows aging in mice.
Journal: Aging cell 20120801
Title: Immunosuppressive drugs on inducing Ag-specific CD4(+)CD25(+)Foxp3(+) Treg cells during immune response in vivo.
Journal: Transplant immunology 20120801
Title: Stability of GABAB receptor oligomers revealed by dual TR-FRET and drug-induced cell surface targeting.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120801
Title: Inhibition of the mTOR/S6K signal is necessary to enhance fluorouracil-induced apoptosis in gastric cancer cells with HER2 amplification.
Journal: International journal of oncology 20120801
Title: Synergistic activity of the mTOR inhibitor ridaforolimus and the antiandrogen bicalutamide in prostate cancer models.
Journal: International journal of oncology 20120801
Title: Sulforaphane, a cruciferous vegetable-derived isothiocyanate, inhibits protein synthesis in human prostate cancer cells.
Journal: Biochimica et biophysica acta 20120801
Title: Monitoring autophagic flux by an improved tandem fluorescent-tagged LC3 (mTagRFP-mWasabi-LC3) reveals that high-dose rapamycin impairs autophagic flux in cancer cells.
Journal: Autophagy 20120801
Title: Impact of oncogenic driver mutations on feedback between the PI3K and MEK pathways in cancer cells.
Journal: Bioscience reports 20120801
Title: Combination of sorafenib and everolimus impacts therapeutically on adrenocortical tumor models.
Journal: Endocrine-related cancer 20120801
Title: Prevention of age-related macular degeneration-like retinopathy by rapamycin in rats.
Journal: The American journal of pathology 20120801
Title: Xience side branch access stent for treatment of bifurcation coronary disease: a review of preclinical data.
Journal: Journal of interventional cardiology 20120801
Title: Phase I study of bevacizumab, everolimus, and panobinostat (LBH-589) in advanced solid tumors.
Journal: Cancer chemotherapy and pharmacology 20120801
Title: TORC1 of fission yeast is rapamycin-sensitive.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20120801
Title: Flow patterns at stented coronary bifurcations: computational fluid dynamics analysis.
Journal: Circulation. Cardiovascular interventions 20120801
Title: Pregnancy in a kidney transplant patient treated with everolimus.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20120801
Title: Non-clear cell renal cell carcinoma: does the mammalian target of rapamycin represent a rational therapeutic target?
Journal: The oncologist 20120801
Title: Targeting angiogenesis in metastatic breast cancer.
Journal: The oncologist 20120801
Title: The mTOR inhibitor everolimus in combination with carboplatin in metastatic breast cancer--a phase I trial.
Journal: Anticancer research 20120801
Title: Brain metastasis in a patient with a sarcomatoid variant RCC with well-controlled extracerebral metastases by temsirolimus.
Journal: Anticancer research 20120801
Title: [Soft-tissue sarcoma: recent developments].
Journal: Deutsche medizinische Wochenschrift (1946) 20120801
Title: How to save Medicare: the anti-aging remedy.
Journal: Aging 20120801
Title: Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian Target of Rapamycin Complex 1.
Journal: PLoS genetics 20120801
Title: Paclitaxcel-coated balloon plus bare metal stent vs. sirolimus-eluting stent in de novo lesions: an IVUS study.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120801
Title: In silico prediction for the investigation of comedication interferences in quantitative LC-MS detection in the SRM mode.
Journal: Bioanalysis 20120801
Title: Stromal cell-derived factor 1α mediates resistance to mTOR-directed therapy in pancreatic cancer.
Journal: Neoplasia (New York, N.Y.) 20120801
Title: Second-generation everolimus-eluting stents versus first-generation sirolimus-eluting stents in acute myocardial infarction. 1-year results of the randomized XAMI (XienceV Stent vs. Cypher Stent in Primary PCI for Acute Myocardial Infarction) trial.
Journal: Journal of the American College of Cardiology 20120731
Title: Transient sequestration of TORC1 into stress granules during heat stress.
Journal: Molecular cell 20120727
Title: Rapamycin attenuates aggressive behavior in a rat model of pilocarpine-induced epilepsy.
Journal: Neuroscience 20120726
Title: Sirolimus and secondary skin-cancer prevention in kidney transplantation.
Journal: The New England journal of medicine 20120726
Title: Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation.
Journal: Science translational medicine 20120725
Title: Rapamycin reverses elevated mTORC1 signaling in lamin A/C-deficient mice, rescues cardiac and skeletal muscle function, and extends survival.
Journal: Science translational medicine 20120725
Title: Multistage pH-responsive liposomes for mitochondrial-targeted anticancer drug delivery.
Journal: Advanced materials (Deerfield Beach, Fla.) 20120717
Title: Protein translocation as a tool: The current rapamycin story.
Journal: FEBS letters 20120716
Title: Preliminary experience with personalized and targeted therapy for pediatric brain tumors.
Journal: Pediatric blood & cancer 20120715
Title: Mammalian target of rapamycin and the kidney. II. Pathophysiology and therapeutic implications.
Journal: American journal of physiology. Renal physiology 20120715
Title: The differential effects of prenatal and/or postnatal rapamycin on neurodevelopmental defects and cognition in a neuroglial mouse model of tuberous sclerosis complex.
Journal: Human molecular genetics 20120715
Title: Calcium/calmodulin-dependent protein kinase IV limits organ damage in hepatic ischemia-reperfusion injury through induction of autophagy.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20120715
Title: Novel agents and new combination treatments on phase I studies on solid tumors and pancreatic cancer.
Journal: JOP : Journal of the pancreas 20120710
Title: Insulin stimulates IGFBP-2 expression in 3T3-L1 adipocytes through the PI3K/mTOR pathway.
Journal: Molecular and cellular endocrinology 20120706
Title: Threonine-120 phosphorylation regulated by phosphoinositide-3-kinase/Akt and mammalian target of rapamycin pathway signaling limits the antitumor activity of mammalian sterile 20-like kinase 1.
Journal: The Journal of biological chemistry 20120706
Title: Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.
Journal: Science translational medicine 20120704
Title: TNFα-mediated apoptosis in human osteoarthritic chondrocytes sensitized by PI3K-NF-κB inhibitor, not mTOR inhibitor.
Journal: Rheumatology international 20120701
Title: Impact of renal insufficiency on safety and efficacy of drug-eluting stents compared to bare-metal stents at 6 years.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120701
Title: Everolimus is an active agent in medullary thyroid cancer: a clinical and in vitro study.
Journal: Journal of cellular and molecular medicine 20120701
Title: Rapamycin affects tissue plasminogen activator and plasminogen activator inhibitor I expression: a potential prothrombotic mechanism of drug-eluting stents.
Journal: Angiology 20120701
Title: Preliminary report of the use of everolimus in a patient with progressive medullary thyroid carcinoma.
Journal: Clinical endocrinology 20120701
Title: Everolimus in combination with cyclosporin a as pre- and posttransplantation immunosuppressive therapy in nonmyeloablative allogeneic hematopoietic stem cell transplantation.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120701
Title: Dasatinib synergizes with both cytotoxic and signal transduction inhibitors in heterogeneous breast cancer cell lines--lessons for design of combination targeted therapy.
Journal: Cancer letters 20120701
Title: A multicenter phase II trial (SAKK 36/06) of single-agent everolimus (RAD001) in patients with relapsed or refractory mantle cell lymphoma.
Journal: Haematologica 20120701
Title: Optimisation of the tumour response threshold in patients treated with everolimus for metastatic renal cell carcinoma: analysis of response and progression-free survival in the RECORD-1 study.
Journal: European journal of cancer (Oxford, England : 1990) 20120701
Title: Different involvement of autophagy in human malignant glioma cell lines undergoing irradiation and temozolomide combined treatments.
Journal: Journal of cellular biochemistry 20120701
Title: Low-dose sirolimus-eluting hydroxyapatite coating on stents does not increase platelet activation and adhesion ex vivo.
Journal: Journal of thrombosis and thrombolysis 20120701
Title: Effects of the combination of RAD001 and docetaxel on breast cancer stem cells.
Journal: European journal of cancer (Oxford, England : 1990) 20120701
Title: What do you do with the antiplatelet agents in patients with drug eluting stents who then receive a mechanical valve?
Journal: Interactive cardiovascular and thoracic surgery 20120701
Title: Phase II study of sirolimus in treatment-naive patients with advanced hepatocellular carcinoma.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120701
Title: Impact of routine angiographic follow-up after percutaneous coronary intervention with drug-eluting stents in the SPIRIT III randomized trial at three years.
Journal: The American journal of cardiology 20120701
Title: Pneumonitis associated with mTOR inhibitors therapy in patients with metastatic renal cell carcinoma: incidence, radiographic findings and correlation with clinical outcome.
Journal: European journal of cancer (Oxford, England : 1990) 20120701
Title: Five-year results of a randomized trial comparing de novo sirolimus and cyclosporine in renal transplantation: the SPIESSER study.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120701
Title: Re: Camillo Porta, Emiliano Calvo, Miguel A. Climent, et al. Efficacy and safety of everolimus in elderly patients with metastatic renal cell carcinoma: an exploratory analysis of the outcomes of elderly patients in the RECORD-1 Trial. Eur Urol 2012;61:826-33.
Journal: European urology 20120701
Title: A randomized, controlled study to assess the conversion from calcineurin-inhibitors to everolimus after liver transplantation--PROTECT.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120701
Title: Functional analysis of the single Est1/Ebs1 homologue in Kluyveromyces lactis reveals roles in both telomere maintenance and rapamycin resistance.
Journal: Eukaryotic cell 20120701
Title: Combination of an allosteric Akt Inhibitor MK-2206 with etoposide or rapamycin enhances the antitumor growth effect in neuroblastoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120701
Title: Simultaneous targeting of EGFR and mTOR inhibits the growth of colorectal carcinoma cells.
Journal: Oncology reports 20120701
Title: Everolimus quantification in peripheral blood mononuclear cells using ultra high performance liquid chromatography tandem mass spectrometry.
Journal: Journal of pharmaceutical and biomedical analysis 20120701
Title: Rapamycin and thrombosis.
Journal: Angiology 20120701
Title: Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood-brain barrier leakage but not microglia activation.
Journal: Epilepsia 20120701
Title: Population pharmacokinetics and pharmacogenetics of everolimus in renal transplant patients.
Journal: Clinical pharmacokinetics 20120701
Title: A phase I study of bevacizumab, everolimus and panitumumab in advanced solid tumors.
Journal: Cancer chemotherapy and pharmacology 20120701
Title: A phase I study of temsirolimus plus carboplatin plus paclitaxel for patients with recurrent or metastatic (R/M) head and neck squamous cell cancer (HNSCC).
Journal: Cancer chemotherapy and pharmacology 20120701
Title: The minimal impact of food on the pharmacokinetics of ridaforolimus.
Journal: Cancer chemotherapy and pharmacology 20120701
Title: A study about drug combination therapy of Schisandra sphenanthera extract and Rapamycin in healthy subjects.
Journal: Canadian journal of physiology and pharmacology 20120701
Title: Caveolin-1 and accelerated host aging in the breast tumor microenvironment: chemoprevention with rapamycin, an mTOR inhibitor and anti-aging drug.
Journal: The American journal of pathology 20120701
Title: Everolimus: a challenging drug in the treatment of multifocal inoperable cardiac rhabdomyoma.
Journal: Pediatrics 20120701
Title: Primary care management of tuberous sclerosis complex in children.
Journal: Journal of the American Academy of Nurse Practitioners 20120701
Title: [Remission of an iatrogenic Kaposi sarcoma in a patient with myasthenia gravis after switching immunosuppressive therapy to the mTOR inhibitor everolimus].
Journal: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20120701
Title: Implications of the new histological classification (WHO 2010) for pancreatic neuroendocrine neoplasms.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20120701
Title: Dimerizer-mediated regulation of gene expression.
Journal: Cold Spring Harbor protocols 20120701
Title: Dimerizer-mediated regulation of gene expression in vitro.
Journal: Cold Spring Harbor protocols 20120701
Title: Dimerizer-mediated regulation of gene expression in vivo.
Journal: Cold Spring Harbor protocols 20120701
Title: Activation of the mTOR pathway in primary medullary thyroid carcinoma and lymph node metastases.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120701
Title: Efficacy of sequential treatment with sunitinib-everolimus in an orthotopic mouse model of renal cell carcinoma.
Journal: Anticancer research 20120701
Title: 14-3-3 protects against stress-induced apoptosis.
Journal: Cell death & disease 20120701
Title: Sirolimus versus calcineurin inhibitor-based immunosuppressive therapy in kidney transplantation: a 4-year follow-up.
Journal: Iranian journal of kidney diseases 20120701
Title: Symptomatic osteonecrosis of the femoral head after adult orthotopic liver transplantation.
Journal: Chinese medical journal 20120701
Title: In vivo evaluation of the delivery and efficacy of a sirolimus-laden polymer gel for inhibition of hyperplasia in a porcine model of arteriovenous hemodialysis graft stenosis.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20120628
Title: Autophagy activation is associated with neuroprotection against apoptosis via a mitochondrial pathway in a rat model of subarachnoid hemorrhage.
Journal: Neuroscience 20120628
Title: mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.
Journal: Nature 20120628
Title: The PP242 mammalian target of rapamycin (mTOR) inhibitor activates extracellular signal-regulated kinase (ERK) in multiple myeloma cells via a target of rapamycin complex 1 (TORC1)/eukaryotic translation initiation factor 4E (eIF-4E)/RAF pathway and activation is a mechanism of resistance.
Journal: The Journal of biological chemistry 20120622
Title: Inhibition of the mTORC2 and chaperone pathways to treat leukemia.
Journal: Blood 20120621
Title: mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma.
Journal: Science translational medicine 20120620
Title: The FKBP-rapamycin binding domain of human TOR undergoes strong conformational changes in the presence of membrane mimetics with and without the regulator phosphatidic acid.
Journal: Biochemistry 20120619
Title: Selective ATP-competitive inhibitors of TOR suppress rapamycin-insensitive function of TORC2 in Saccharomyces cerevisiae.
Journal: ACS chemical biology 20120615
Title: Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence.
Journal: Cell cycle (Georgetown, Tex.) 20120615
Title: Suppression of replicative senescence by rapamycin in rodent embryonic cells.
Journal: Cell cycle (Georgetown, Tex.) 20120615
Title: Review of cytomegalovirus infection findings with mammalian target of rapamycin inhibitor-based immunosuppressive therapy in de novo renal transplant recipients.
Journal: Transplantation 20120615
Title: Identification and expansion of highly suppressive CD8(+)FoxP3(+) regulatory T cells after experimental allogeneic bone marrow transplantation.
Journal: Blood 20120614
Title: Long-term clinical and angiographic outcome after treatment of chronic total occlusion with everolimus or sirolimus eluting stents.
Journal: International journal of cardiology 20120614
Title: Short- and long-term outcomes with drug-eluting and bare-metal coronary stents: a mixed-treatment comparison analysis of 117 762 patient-years of follow-up from randomized trials.
Journal: Circulation 20120612
Title: Lipopolysaccharide induction of autophagy is associated with enhanced bactericidal activity in Dictyostelium discoideum.
Journal: Biochemical and biophysical research communications 20120608
Title: Further developments for improving response and tolerance to irradiation for advanced renal cancer: concurrent (mTOR) inhibitor RAD001 and helical tomotherapy.
Journal: Investigational new drugs 20120601
Title: Everolimus-related organizing pneumonia: a report establishing causality.
Journal: Investigational new drugs 20120601
Title: Temsirolimus in renal cell carcinoma with sarcomatoid differentiation: a report of three cases.
Journal: Medical oncology (Northwood, London, England) 20120601
Title: p70 S6K1 nuclear localization depends on its mTOR-mediated phosphorylation at T389, but not on its kinase activity towards S6.
Journal: Amino acids 20120601
Title: Combination or sequencing strategies to improve the outcome of metastatic renal cell carcinoma patients: a critical review.
Journal: Critical reviews in oncology/hematology 20120601
Title: 40-O -[2-Hydroxyethyl]rapamycin modulates human dendritic cell function during exposure to Aspergillus fumigatus.
Journal: Journal of basic microbiology 20120601
Title: Alpha-ketoglutarate inhibits glutamine degradation and enhances protein synthesis in intestinal porcine epithelial cells.
Journal: Amino acids 20120601
Title: Early treatment with everolimus exerts nephroprotective effect in rats with adriamycin-induced nephrotic syndrome.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120601
Title: Primary anti-vascular endothelial growth factor (VEGF)-refractory metastatic renal cell carcinoma: clinical characteristics, risk factors, and subsequent therapy.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20120601
Title: Autophagy modulates osteoarthritis-related gene expression in human chondrocytes.
Journal: Arthritis and rheumatism 20120601
Title: Rapamycin and a hyaluronic acid-carboxymethylcellulose membrane did not lead to reduced adhesion formations in a rat abdominal adhesion model.
Journal: Archives of gynecology and obstetrics 20120601
Title: Interstitial pneumonitis is a frequent complication in liver transplant recipients treated with sirolimus.
Journal: Irish journal of medical science 20120601
Title: Is there a role for targeted therapies in the collecting ducts of Bellini carcinoma? Efficacy data from a retrospective analysis of 7 cases.
Journal: Clinical and experimental nephrology 20120601
Title: Impact of incomplete stent apposition on long-term clinical outcome after drug-eluting stent implantation.
Journal: European heart journal 20120601
Title: Inhibition of neointimal hyperplasia with a novel zotarolimus coated balloon catheter.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20120601
Title: Hypothalamic mTOR pathway mediates thyroid hormone-induced hyperphagia in hyperthyroidism.
Journal: The Journal of pathology 20120601
Title: Regulatory T cells exhibit decreased proliferation but enhanced suppression after pulsing with sirolimus.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120601
Title: Inhibition of mammalian target of rapamycin signaling by CCI-779 (temsirolimus) induces growth inhibition and cell cycle arrest in Cashmere goat fetal fibroblasts (Capra hircus).
Journal: DNA and cell biology 20120601
Title: Combination of Temsirolimus and tyrosine kinase inhibitors in renal carcinoma and endothelial cell lines.
Journal: Journal of cancer research and clinical oncology 20120601
Title: Sirolimus protective effects on bone: the need to be demonstrated.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120601
Title: Cyclosporine lowering with everolimus versus mycophenolate mofetil in heart transplant recipients: long-term follow-up of the SHIRAKISS randomized, prospective study.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120601
Title: Mammalian target of rapamycin: a valid therapeutic target through the autophagy pathway for Alzheimer's disease?
Journal: Journal of neuroscience research 20120601
Title: Post-transcriptional modulation of C/EBPα prompts monocytic differentiation and apoptosis in acute myelomonocytic leukaemia cells.
Journal: Leukemia research 20120601
Title: Modulation of mTOR effector phosphoproteins in blood basophils from allergic patients.
Journal: Journal of clinical immunology 20120601
Title: System for integrated adherence monitoring: real-time non-adherence risk assessment in pediatric kidney transplantation.
Journal: Pediatric transplantation 20120601
Title: Modulation of sodium iodide symporter expression and function by LY294002, Akti-1/2 and Rapamycin in thyroid cells.
Journal: Endocrine-related cancer 20120601
Title: A single-dose placebo- and moxifloxacin-controlled study of the effects of temsirolimus on cardiac repolarization in healthy adults.
Journal: Cancer chemotherapy and pharmacology 20120601
Title: Immunophyllin ligands show differential effects on alcohol self-administration in C57BL mice.
Journal: The Journal of pharmacology and experimental therapeutics 20120601
Title: Ghrelin contributes to derangements of glucose metabolism induced by rapamycin in mice.
Journal: Diabetologia 20120601
Title: Gli inhibitor GANT61 causes apoptosis in myeloid leukemia cells and acts in synergy with rapamycin.
Journal: Leukemia research 20120601
Title: The role of mTOR inhibitors in the inhibition of growth and cortisol secretion in human adrenocortical carcinoma cells.
Journal: Endocrine-related cancer 20120601
Title: A novel library screen identifies immunosuppressors that promote osteoblast differentiation.
Journal: Bone 20120601
Title: Everolimus-eluting versus sirolimus-eluting stents: an updated meta-analysis of randomized trials.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20120601
Title: Influence of diabetes mellitus on long-term (five-year) outcomes of drug-eluting stents and coronary artery bypass grafting for multivessel coronary revascularization.
Journal: The American journal of cardiology 20120601
Title: Pancreatic neuroendocrine and carcinoid tumors: what's new, what's old, and what's different?
Journal: Current oncology reports 20120601
Title: Effect of everolimus on pre-existing atherosclerosis in LDL-receptor deficient mice.
Journal: Atherosclerosis 20120601
Title: Measuring adherence to medications: are complex methods superior to simple ones?
Journal: Pediatric transplantation 20120601
Title: Inhibition of mTORC1 kinase activates Smads 1 and 5 but not Smad8 in human prostate cancer cells, mediating cytostatic response to rapamycin.
Journal: Molecular cancer research : MCR 20120601
Title: Subconjunctival sirolimus for the treatment of chronic active anterior uveitis: results of a pilot trial.
Journal: American journal of ophthalmology 20120601
Title: Major involvement of mTOR in the PPARγ-induced stimulation of adipose tissue lipid uptake and fat accretion.
Journal: Journal of lipid research 20120601
Title: Luteinizing hormone facilitates angiogenesis in ovarian epithelial tumor cells and metformin inhibits the effect through the mTOR signaling pathway.
Journal: Oncology reports 20120601
Title: The impact of sirolimus on sex hormones in male adolescent kidney recipients.
Journal: Pediatric transplantation 20120601
Title: Increase in cholesterol predicts survival advantage in renal cell carcinoma patients treated with temsirolimus.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120601
Title: Immunosuppressive regimen and interstitial fibrosis and tubules atrophy at 12 months postrenal transplant.
Journal: Clinical journal of the American Society of Nephrology : CJASN 20120601
Title: Combination of Rad001 (everolimus) and propachlor synergistically induces apoptosis through enhanced autophagy in prostate cancer cells.
Journal: Molecular cancer therapeutics 20120601
Title: A role of the mammalian target of rapamycin (mTOR) in glutamate-induced down-regulation of tuberous sclerosis complex proteins 2 (TSC2).
Journal: Journal of molecular neuroscience : MN 20120601
Title: Endothelial-dependent vasomotion in a coronary segment treated by ABSORB everolimus-eluting bioresorbable vascular scaffold system is related to plaque composition at the time of bioresorption of the polymer: indirect finding of vascular reparative therapy?
Journal: European heart journal 20120601
Title: Serum cholesterol and mTOR inhibitors: surrogate biomarker or epiphenomenon?
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120601
Title: Circulating biomarkers of response to sunitinib in gastroenteropancreatic neuroendocrine tumors: current data and clinical outlook.
Journal: Molecular diagnosis & therapy 20120601
Title: Cordycepin as a sensitizer to tumour necrosis factor (TNF)-α-induced apoptosis through eukaryotic translation initiation factor 2α (eIF2α)- and mammalian target of rapamycin complex 1 (mTORC1)-mediated inhibition of nuclear factor (NF)-κB.
Journal: Clinical and experimental immunology 20120601
Title: Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response.
Journal: Biochimica et biophysica acta 20120601
Title: Results of a phase II study of sirolimus and cyclophosphamide in patients with advanced sarcoma.
Journal: European journal of cancer (Oxford, England : 1990) 20120601
Title: Effect of sirolimus on the regression of peritoneal sclerosis in an experimental rat model.
Journal: International urology and nephrology 20120601
Title: Histopathological comparison of biodegradable polymer and permanent polymer based sirolimus eluting stents in a porcine model of coronary stent implantation.
Journal: Thrombosis and haemostasis 20120601
Title: Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20120601
Title: A further step towards vascular reparative therapy.
Journal: European heart journal 20120601
Title: SIRT1 is required for the effects of rapamycin on high glucose-inducing mesangial cells senescence.
Journal: Mechanisms of ageing and development 20120601
Title: Autophagy and cardiovascular aging: lesson learned from rapamycin.
Journal: Cell cycle (Georgetown, Tex.) 20120601
Title: New targeted agents in gastroenteropancreatic neuroendocrine tumors.
Journal: Targeted oncology 20120601
Title: Everolimus in different combinations as maintenance immunosuppressive therapy in heart transplant recipients.
Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120601
Title: Everolimus-induced lymphedema in a renal transplant recipient: a case report.
Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120601
Title: Conversion from cyclosporine to everolimus at 4.5 months posttransplant: 3-year results from the randomized ZEUS study.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120601
Title: [Renal carcinoma: point on treatment of brain metastasis].
Journal: Bulletin du cancer 20120601
Title: Peritoneovenous shunt for chylous ascites after lung transplantation for lymphangioleiomyomatosis.
Journal: Transplantation proceedings 20120601
Title: Gender differences in patients treated with the zotarolimus-eluting stent at a tertiary medical center.
Journal: The Journal of invasive cardiology 20120601
Title: Targeting mTOR in mantle cell lymphoma: current and future directions.
Journal: Best practice & research. Clinical haematology 20120601
Title: Malignant perivascular epithelioid cell tumor in children: description of a case and review of the literature.
Journal: Journal of pediatric surgery 20120601
Title: Lymphedema of the breast as a symptom of internal diseases or side effect of mTor inhibitors.
Journal: Lymphatic research and biology 20120601
Title: Contemporary incidence and predictors of stent thrombosis and other major adverse cardiac events in the year after XIENCE V implantation: results from the 8,061-patient XIENCE V United States study.
Journal: JACC. Cardiovascular interventions 20120601
Title: The role of autophagy during coxsackievirus infection of neural progenitor and stem cells.
Journal: Autophagy 20120601
Title: Dissecting mammalian target of rapamycin to promote longevity.
Journal: Rejuvenation research 20120601
Title: The BOLERO-2 trial: the addition of everolimus to exemestane in the treatment of postmenopausal hormone receptor-positive advanced breast cancer.
Journal: Future oncology (London, England) 20120601
Title: Medium to long-term clinical outcomes with everolimus-eluting stents in real-life percutaneous coronary intervention.
Journal: Annals of the Academy of Medicine, Singapore 20120601
Title: Proteinuria following sirolimus conversion is associated with deterioration of kidney function in liver transplant recipients.
Journal: Transplantation 20120527
Title: Evaluation of the peri-strut low intensity area following sirolimus- and paclitaxel-eluting stents implantation: insights from an optical coherence tomography study in humans.
Journal: International journal of cardiology 20120517
Title: Clinical performance of a drug-eluting stent with a biodegradable polymer in an unselected patient population: the NOBORI 2 study.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120515
Title: mTOR inhibition with rapamycin causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes.
Journal: Molecular and cellular endocrinology 20120515
Title: Sirolimus-associated testicular toxicity: detrimental but reversible.
Journal: Transplantation 20120515
Title: Impact of statin therapy on late target lesion revascularization after sirolimus-eluting stent implantation (from the CREDO-Kyoto Registry Cohort-2).
Journal: The American journal of cardiology 20120515
Title: Radiochemical high-performance liquid chromatography detection of arginine metabolism in human endothelial cells.
Journal: Analytical biochemistry 20120515
Title: Stable isotope-labelling analysis of the impact of inhibition of the mammalian target of rapamycin on protein synthesis.
Journal: The Biochemical journal 20120515
Title: Impact of age on clinical outcomes after everolimus-eluting and paclitaxel-eluting stent implantation: pooled analysis from the SPIRIT III and SPIRIT IV clinical trials.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120515
Title: Late clinical outcomes after implantation of drug-eluting stents coated with biodegradable polymers: 3-year follow-up of the PAINT randomised trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120515
Title: Inhibition of influenza A virus replication by antagonism of a PI3K-AKT-mTOR pathway member identified by gene-trap insertional mutagenesis.
Journal: Antiviral chemistry & chemotherapy 20120514
Title: Use of sirolimus in patients with primary steroid-resistant nephrotic syndrome.
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20120514
Title: Reduction of Na/K-ATPase potentiates marinobufagenin-induced cardiac dysfunction and myocyte apoptosis.
Journal: The Journal of biological chemistry 20120511
Title: A perivascular system releasing sirolimus prevented intimal hyperplasia in a rabbit model in a medium-term study.
Journal: International journal of pharmaceutics 20120510
Title: Regulation of the glutamate transporter EAAT3 by mammalian target of rapamycin mTOR.
Journal: Biochemical and biophysical research communications 20120504
Title: Flat panel digital detector cinefluoroscopy late following SES or BMS implantation for detection of coronary stent fracture in asymptomatic patients.
Journal: International journal of cardiology 20120503
Title: Everolimus in HR-positive advanced breast cancer.
Journal: The New England journal of medicine 20120503
Title: Everolimus in HR-positive advanced breast cancer.
Journal: The New England journal of medicine 20120503
Title: TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO.
Journal: Cell metabolism 20120502
Title: Agreement and reproducibility of gray-scale intravascular ultrasound and optical coherence tomography for the analysis of the bioresorbable vascular scaffold.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501
Title: Seven-year safety and efficacy of the unrestricted use of drug-eluting stents in saphenous vein bypass grafts.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501
Title: Combination testing (Stage 2) of the Anti-IGF-1 receptor antibody IMC-A12 with rapamycin by the pediatric preclinical testing program.
Journal: Pediatric blood & cancer 20120501
Title: Successful coronary intervention of chronic total occlusion of the right coronary artery by ipsilateral injection via an isolated conus artery.
Journal: Heart and vessels 20120501
Title: A phase 1 study of weekly everolimus (RAD001) in combination with docetaxel in patients with metastatic breast cancer.
Journal: Cancer 20120501
Title: Suppression of neointimal hyperplasia by sirolimus-eluting expanded polytetrafluoroethylene (ePTFE) haemodialysis grafts in comparison with paclitaxel-coated grafts.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120501
Title: Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity.
Journal: Journal of molecular medicine (Berlin, Germany) 20120501
Title: Repeat-dose sirolimus pharmacokinetics and pharmacodynamics in patients with hepatic allografts.
Journal: European journal of clinical pharmacology 20120501
Title: The union of anti-CD34 antibody can improve the performance of drug-eluting stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501
Title: Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: assembly of a multiprotein signaling complex.
Journal: Journal of cellular biochemistry 20120501
Title: Molecular characterization and functional analysis of Cashmere goat mammalian target of rapamycin.
Journal: DNA and cell biology 20120501
Title: Magnetic stents retain nanoparticle-bound antirestenotic drugs transported by lipid microbubbles.
Journal: Pharmaceutical research 20120501
Title: Assay validation of phosphorylated S6 ribosomal protein for a pharmacodynamic monitoring of mTOR-inhibitors in peripheral human blood.
Journal: Cytometry. Part B, Clinical cytometry 20120501
Title: Analysis of the pharmacodynamic activity of the mTOR inhibitor ridaforolimus (AP23573, MK-8669) in a phase 1 clinical trial.
Journal: Cancer chemotherapy and pharmacology 20120501
Title: Sorafenib for recurrence of hepatocellular carcinoma after liver transplantation.
Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120501
Title: Preparation and optimization of media using Pluronic® micelles for solubilization of sirolimus and release from the drug eluting stents.
Journal: Colloids and surfaces. B, Biointerfaces 20120501
Title: V-AKT murine thymoma viral oncogene homolog/mammalian target of rapamycin activation induces a module of metabolic changes contributing to growth in insulin-induced hepatocarcinogenesis.
Journal: Hepatology (Baltimore, Md.) 20120501
Title: Sustained antitumor activity by co-targeting mTOR and the microtubule with temsirolimus/vinblastine combination in hepatocellular carcinoma.
Journal: Biochemical pharmacology 20120501
Title: The effect of multiple doses of rifampin and ketoconazole on the single-dose pharmacokinetics of ridaforolimus.
Journal: Cancer chemotherapy and pharmacology 20120501
Title: Everolimus exhibits efficacy as a radiosensitizer in a model of non-small cell lung cancer.
Journal: Oncology reports 20120501
Title: Impact of sirolimus duration on hepatitis C related fibrosis progression in liver transplant recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120501
Title: An indirect comparison of everolimus versus sorafenib in metastatic renal cell carcinoma - a flawed analysis?
Journal: Expert opinion on pharmacotherapy 20120501
Title: Donor-specific HLA antibodies in a cohort comparing everolimus with cyclosporine after kidney transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120501
Title: Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2).
Journal: Diabetologia 20120501
Title: Akt inhibitors MK-2206 and nelfinavir overcome mTOR inhibitor resistance in diffuse large B-cell lymphoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120501
Title: Safety and efficacy of the XIENCE V everolimus-eluting stent compared to first-generation drug-eluting stents in contemporary clinical practice.
Journal: The American journal of cardiology 20120501
Title: Dose-dependent effects of sirolimus on mTOR signaling and polycystic kidney disease.
Journal: Journal of the American Society of Nephrology : JASN 20120501
Title: Everolimus triggers cytokine release by macrophages: rationale for stents eluting everolimus and a glucocorticoid.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20120501
Title: Systemic rapamycin alone may not be a treatment option for malignant glioma: evidence from an in vivo study.
Journal: Journal of neuro-oncology 20120501
Title: Acute depletion of plasma membrane phosphatidylinositol 4,5-bisphosphate impairs specific steps in endocytosis of the G-protein-coupled receptor.
Journal: Journal of cell science 20120501
Title: Treatment of congenital tracheal stenosis by balloon-expandable metallic stents in paediatric intensive care unit.
Journal: Interactive cardiovascular and thoracic surgery 20120501
Title: Autophagy proteins play cytoprotective and cytocidal roles in leucine starvation-induced cell death in Saccharomyces cerevisiae.
Journal: Autophagy 20120501
Title: Effects of rapamycin-induced oligomerization of parvalbumin, Stim1 and Orai1 in puncta formation.
Journal: Cell calcium 20120501
Title: The impact of sirolimus on sex hormones in male adolescent kidney recipients.
Journal: Pediatric transplantation 20120501
Title: Prolonged survival of allogeneic islets in cynomolgus monkeys after short-term triple therapy.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120501
Title: Cavitatory lung disease in thoracic transplant recipients receiving sirolimus.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120501
Title: mTOR is required for asymmetric division through small GTPases in mouse oocytes.
Journal: Molecular reproduction and development 20120501
Title: mTOR as a molecular target in HPV-associated oral and cervical squamous carcinomas.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120501
Title: Randomized controlled trial of sirolimus for renal transplant recipients at high risk for nonmelanoma skin cancer.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120501
Title: Regulation of mTOR complex 2 signaling in neurofibromatosis 2-deficient target cell types.
Journal: Molecular cancer research : MCR 20120501
Title: Patterns of interstitial lung disease during everolimus treatment in patients with metastatic renal cell carcinoma.
Journal: Japanese journal of clinical oncology 20120501
Title: Limus is not limus--a proposal to adjust terminology in the context of drug-eluting stents.
Journal: Journal of cardiovascular pharmacology 20120501
Title: Biodegradable polymer drug-eluting stents reduce the risk of stent thrombosis at 4 years in patients undergoing percutaneous coronary intervention: a pooled analysis of individual patient data from the ISAR-TEST 3, ISAR-TEST 4, and LEADERS randomized trials.
Journal: European heart journal 20120501
Title: Inhibition of mammalian target of rapamycin augments lipopolysaccharide-induced lung injury and apoptosis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20120501
Title: Insulin growth factor-receptor (IGF-1R) antibody cixutumumab combined with the mTOR inhibitor temsirolimus in patients with refractory Ewing's sarcoma family tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120501
Title: Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice.
Journal: The Journal of clinical investigation 20120501
Title: Cyclosporin but not everolimus inhibits chemokine receptor expression on CD4+ T cell subsets circulating in the peripheral blood of renal transplant recipients.
Journal: Clinical and experimental immunology 20120501
Title: Everolimus plus early tacrolimus minimization: a phase III, randomized, open-label, multicentre trial in renal transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20120501
Title: Possible correlation of sirolimus plasma concentration with sinusoidal obstructive syndrome of the liver in patients undergoing myeloablative allogeneic hematopoietic cell transplantation.
Journal: Pharmacotherapy 20120501
Title: A brain aggregate model gives new insights into the pathobiology and treatment of prion diseases.
Journal: Journal of neuropathology and experimental neurology 20120501
Title: Objective versus subjective guidance of (bioabsorbable) stent implantation: the saga continues.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501
Title: Proximal and distal maximal luminal diameters as a guide to appropriate deployment of the ABSORB everolimus-eluting bioresorbable vascular scaffold: a sub-study of the ABSORB Cohort B and the on-going ABSORB EXTEND Single Arm Study.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501
Title: Emerging treatments in the management of tuberous sclerosis complex.
Journal: Pediatric neurology 20120501
Title: mTOR inhibitors: a myth, a cure for cancer or something in between?
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120501
Title: Comment on 'Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells' Haematologica 2011;96(9):1357-65.
Journal: Haematologica 20120501
Title: Cardiac allograft vasculopathy compared by intravascular ultrasound sonography: everolimus to mycophenolate mofetil--one single-center experience.
Journal: Transplantation proceedings 20120501
Title: Clinical experience of tacrolimus with everolimus in heart transplantation.
Journal: Transplantation proceedings 20120501
Title: Metformin and the mTOR inhibitor everolimus (RAD001) sensitize breast cancer cells to the cytotoxic effect of chemotherapeutic drugs in vitro.
Journal: Anticancer research 20120501
Title: The SPIRIT V diabetic study: a randomized clinical evaluation of the XIENCE V everolimus-eluting stent vs the TAXUS Liberté paclitaxel-eluting stent in diabetic patients with de novo coronary artery lesions.
Journal: American heart journal 20120501
Title: Long-term clinical and angiographic outcomes of diabetic patients after revascularization with early generation drug-eluting stents.
Journal: American heart journal 20120501
Title: The impact of preprocedural hemoglobin A1c on the efficacy of sirolimus-eluting and paclitaxel-eluting stents.
Journal: Cardiovascular intervention and therapeutics 20120501
Title: Stability of ready-to-use temsirolimus infusion solution (100mg/L) in polypropylene containers under different storage conditions.
Journal: Annales pharmaceutiques francaises 20120501
Title: Systemic exposure of sirolimus after coronary stent implantation in patients with de novo coronary lesions: Supralimus-Core® pharmacokinetic study.
Journal: Indian heart journal 20120501
Title: Once again on rapamycin-induced insulin resistance and longevity: despite of or owing to.
Journal: Aging 20120501
Title: [Progress and extensive meaning of mammalian target of rapamycin involved in restoration of nervous system injury].
Journal: Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20120501
Title: Brief report: a phase II 'window-of-opportunity' frontline study of the MTOR inhibitor, temsirolimus given as a single agent in patients with advanced NSCLC, an NCCTG study.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20120501
Title: Late subcapsular lymphocele in a kidney graft.
Journal: Transplantation 20120427
Title: The pan-deacetylase inhibitor panobinostat induces cell death and synergizes with everolimus in Hodgkin lymphoma cell lines.
Journal: Blood 20120426
Title: Regulation of presynaptic neurotransmission by macroautophagy.
Journal: Neuron 20120426
Title: Short- versus long-term duration of dual-antiplatelet therapy after coronary stenting: a randomized multicenter trial.
Journal: Circulation 20120424
Title: Everolimus in metastatic renal cell carcinoma patients intolerant to previous VEGFr-TKI therapy: a RECORD-1 subgroup analysis.
Journal: British journal of cancer 20120424
Title: Drug-eluting vs bare-metal stents in primary angioplasty: a pooled patient-level meta-analysis of randomized trials.
Journal: Archives of internal medicine 20120423
Title: Effect of persistent activation of phosphoinositide 3-kinase on heart.
Journal: Life sciences 20120420
Title: PI3-kinase and mTOR inhibitors differently modulate the function of the ABCG2 multidrug transporter.
Journal: Biochemical and biophysical research communications 20120420
Title: Surface crystallization of rapamycin on stents using a temperature induced process.
Journal: Langmuir : the ACS journal of surfaces and colloids 20120417
Title: Rapamycin with antiretroviral therapy in AIDS-associated Kaposi sarcoma: an AIDS Malignancy Consortium study.
Journal: Journal of acquired immune deficiency syndromes (1999) 20120415
Title: Murine islet allograft tolerance upon blockade of the B-lymphocyte stimulator, BLyS/BAFF.
Journal: Transplantation 20120415
Title: Blocking mTORC1 activity by rapamycin leads to impairment of spatial memory retrieval but not acquisition in C57BL/6J mice.
Journal: Behavioural brain research 20120415
Title: Production of interferon α by human immunodeficiency virus type 1 in human plasmacytoid dendritic cells is dependent on induction of autophagy.
Journal: The Journal of infectious diseases 20120415
Title: The struggle for energy in podocytes leads to nephrotic syndrome.
Journal: Cell cycle (Georgetown, Tex.) 20120415
Title: Stent thrombosis with drug-eluting and bare-metal stents: evidence from a comprehensive network meta-analysis.
Journal: Lancet (London, England) 20120414
Title: Controlled release formulations of IL-2, TGF-β1 and rapamycin for the induction of regulatory T cells.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20120410
Title: Primary endpoint results of the EVOLVE trial: a randomized evaluation of a novel bioabsorbable polymer-coated, everolimus-eluting coronary stent.
Journal: Journal of the American College of Cardiology 20120410
Title: A randomized controlled trial in second-generation zotarolimus-eluting Resolute stents versus everolimus-eluting Xience V stents in real-world patients: the TWENTE trial.
Journal: Journal of the American College of Cardiology 20120410
Title: Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells.
Journal: The Journal of biological chemistry 20120406
Title: Des-acyl ghrelin exhibits pro-anabolic and anti-catabolic effects on C2C12 myotubes exposed to cytokines and reduces burn-induced muscle proteolysis in rats.
Journal: Molecular and cellular endocrinology 20120404
Title: Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling.
Journal: Cell metabolism 20120404
Title: Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice.
Journal: The Journal of clinical investigation 20120402
Title: A phase I study of temsirolimus and metformin in advanced solid tumours.
Journal: Investigational new drugs 20120401
Title: Combination testing of cediranib (AZD2171) against childhood cancer models by the pediatric preclinical testing program.
Journal: Pediatric blood & cancer 20120401
Title: Sirolimus and mycophenolate mofetil as GVHD prophylaxis in myeloablative, matched-related donor hematopoietic cell transplantation.
Journal: Bone marrow transplantation 20120401
Title: Major determinants for the uncovered stent struts on optical coherence tomography after drug-eluting stent implantation.
Journal: The international journal of cardiovascular imaging 20120401
Title: Optical coherence tomography findings of very late stent thrombosis after drug-eluting stent implantation.
Journal: The international journal of cardiovascular imaging 20120401
Title: Combination of targeted agents in metastatic renal cell carcinoma: a path forward or a dead-end street?
Journal: Cancer 20120401
Title: Phase 1 trial of everolimus plus sunitinib in patients with metastatic renal cell carcinoma.
Journal: Cancer 20120401
Title: Chronic mTOR inhibition by rapamycin induces muscle insulin resistance despite weight loss in rats.
Journal: British journal of pharmacology 20120401
Title: Krüppel-like factor 4 is induced by rapamycin and mediates the anti-proliferative effect of rapamycin in rat carotid arteries after balloon injury.
Journal: British journal of pharmacology 20120401
Title: Mechanical injury suppresses autophagy regulators and pharmacologic activation of autophagy results in chondroprotection.
Journal: Arthritis and rheumatism 20120401
Title: Ridaforolimus for patients with progressive or recurrent malignant glioma: a perisurgical, sequential, ascending-dose trial.
Journal: Cancer chemotherapy and pharmacology 20120401
Title: Dynamic contrast-enhanced micro-CT on mice with mammary carcinoma for the assessment of antiangiogenic therapy response.
Journal: European radiology 20120401
Title: Autophagy activation by rapamycin reduces severity of experimental osteoarthritis.
Journal: Annals of the rheumatic diseases 20120401
Title: Morphological and degradation studies of sirolimus-containing poly(lactide-co-glycolide) discs.
Journal: Journal of biomedical materials research. Part B, Applied biomaterials 20120401
Title: Molecular targeted agents for gastric and gastroesophageal junction cancer.
Journal: Surgery today 20120401
Title: Phase I study for ridaforolimus, an oral mTOR inhibitor, in Japanese patients with advanced solid tumors.
Journal: Cancer chemotherapy and pharmacology 20120401
Title: Identification of a novel biomarker gene set with sensitivity and specificity for distinguishing between allograft rejection and tolerance.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120401
Title: Combined mTOR inhibition and OX40 agonism enhances CD8(+) T cell memory and protective immunity produced by recombinant adenovirus vaccines.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20120401
Title: Regulatory T cells expanded by rapamycin in vitro suppress colitis in an experimental mouse model.
Journal: Journal of gastroenterology 20120401
Title: Immunosuppressive drug rapamycin restores sporulation competence in industrial yeasts.
Journal: Journal of bioscience and bioengineering 20120401
Title: Pharmacologic inhibition of mTOR antagonizes the cytotoxic activity of pemetrexed in non-small cell lung cancer.
Journal: Journal of cancer research and clinical oncology 20120401
Title: Regulation of physiologic actions of LRRK2: focus on autophagy.
Journal: Neuro-degenerative diseases 20120401
Title: Autophagy is a cell death mechanism in Toxoplasma gondii.
Journal: Cellular microbiology 20120401
Title: Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling.
Journal: Aging cell 20120401
Title: Meta-analysis of long-term outcomes for drug-eluting stents versus bare-metal stents in primary percutaneous coronary interventions for ST-segment elevation myocardial infarction.
Journal: The American journal of cardiology 20120401
Title: TOR signaling is involved in PTTH-stimulated ecdysteroidogenesis by prothoracic glands in the silkworm, Bombyx mori.
Journal: Insect biochemistry and molecular biology 20120401
Title: Development of a combination drug-eluting bead: towards enhanced efficacy for locoregional tumour therapies.
Journal: Anti-cancer drugs 20120401
Title: Determination of everolimus in blood samples from kidney and liver transplant recipients using the sirolimus chemiluminescence magnetic microparticle immunoassay (CMIA) on the Architect-i1000® system.
Journal: Scandinavian journal of clinical and laboratory investigation 20120401
Title: Adhesion and cohesion in structures containing suspended microscopic polymeric films.
Journal: Acta biomaterialia 20120401
Title: Radical reduction of smooth muscle cells in explanted lung of a LAM patient treated with sirolimus: first case report.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120401
Title: Everolimus-eluting stents and paclitaxel-eluting stents in patients presenting with myocardial infarction: insights from the two-year results of the COMPARE prospective randomised controlled trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401
Title: Potential of T-regulatory cells to protect xenografts.
Journal: Current opinion in organ transplantation 20120401
Title: Induced regulatory T cells: mechanisms of conversion and suppressive potential.
Journal: Human immunology 20120401
Title: Efficacy and safety of everolimus in elderly patients with metastatic renal cell carcinoma: an exploratory analysis of the outcomes of elderly patients in the RECORD-1 Trial.
Journal: European urology 20120401
Title: TORC2 signaling is antagonized by protein phosphatase 2A and the Far complex in Saccharomyces cerevisiae.
Journal: Genetics 20120401
Title: Role of rapamycin-induced autophagy in pancreatic islets.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120401
Title: Comparison of biolimus eluted from an erodible stent coating with bare metal stents in acute ST-elevation myocardial infarction (COMFORTABLE AMI trial): rationale and design.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401
Title: Rapamycin resistance is linked to defective regulation of Skp2.
Journal: Cancer research 20120401
Title: Immunological advantages of everolimus versus cyclosporin A in liver-transplanted recipients, as revealed by polychromatic flow cytometry.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20120401
Title: Early conversion to a sirolimus-based, calcineurin-inhibitor-free immunosuppression in the SMART trial: observational results at 24 and 36months after transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20120401
Title: Analytical performance of a new liquid chromatography/tandem mass spectrometric method for determination of everolimus concentrations in whole blood.
Journal: Therapeutic drug monitoring 20120401
Title: New strategies for advanced neuroendocrine tumors in the era of targeted therapy.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120401
Title: Effects of an agonist interleukin-2/Fc fusion protein, a mutant antagonist interleukin-15/Fc fusion protein, and sirolimus on cardiac allograft survival in non-human primates.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120401
Title: Regulating mammalian target of rapamycin to tune vaccination-induced CD8(+) T cell responses for tumor immunity.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20120401
Title: Blue rubber bleb nevus syndrome: successful treatment with sirolimus.
Journal: Pediatrics 20120401
Title: Comparison of 5-year clinical outcomes between sirolimus-versus paclitaxel-eluting stent: Korean multicenter network analysis of 9000-patient cohort.
Journal: Circulation. Cardiovascular interventions 20120401
Title: Everolimus: preventing organ rejection in adult kidney transplant recipients.
Journal: Expert opinion on pharmacotherapy 20120401
Title: Impact of stenting and oral sirolimus on endothelium-dependent and independent coronary vasomotion.
Journal: Arquivos brasileiros de cardiologia 20120401
Title: Long-term results of conversion from calcineurin inhibitors to sirolimus in 150 maintenance kidney transplant patients.
Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120401
Title: Sirolimus conversion in liver transplant recipients with calcineurin inhibitor-induced complications: efficacy and safety.
Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120401
Title: Periprocedural myocardial infarction in a randomized trial of everolimus-eluting and Paclitaxel-eluting coronary stents: frequency and impact on mortality according to historic versus universal definitions.
Journal: Circulation. Cardiovascular interventions 20120401
Title: Targeting autophagy for drug-induced hepatotoxicity.
Journal: Autophagy 20120401
Title: Everolimus: targeted therapy on the horizon for the treatment of breast cancer.
Journal: Pharmacotherapy 20120401
Title: Autophagy: a new therapeutic target in cartilage injury and osteoarthritis.
Journal: The Journal of the American Academy of Orthopaedic Surgeons 20120401
Title: Acute ST-elevation myocardial infarction 6 years following a sirolimus-eluting stent secondary to complete stent fracture.
Journal: The Journal of invasive cardiology 20120401
Title: Successful sealing of a coronary artery perforation with a mesh-covered stent.
Journal: The Journal of invasive cardiology 20120401
Title: The 4-week serum creatinine level predicts long-term renal dysfunction after adult living donor liver transplantation.
Journal: Transplantation proceedings 20120401
Title: Rapamycin combined with allogenic immature dendritic cells selectively expands CD4+CD25+Foxp3+ regulatory T cells in rats.
Journal: Hepatobiliary & pancreatic diseases international : HBPD INT 20120401
Title: Suppression of autophagy is protective in high glucose-induced cardiomyocyte injury.
Journal: Autophagy 20120401
Title: Breakthroughs in myeloproliferative neoplasms.
Journal: Hematology (Amsterdam, Netherlands) 20120401
Title: mTOR-dependent modulation of gastric nesfatin-1/NUCB2.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120401
Title: The prequel: defining prognostically important criteria in the periprocedural PCI troponin saga.
Journal: Circulation. Cardiovascular interventions 20120401
Title: Magnetic nanoparticles and rapamycin encapsulated into polymeric nanocarriers.
Journal: Journal of biomedical nanotechnology 20120401
Title: Differences in neointimal thickness between the adluminal and the abluminal sides of malapposed and side-branch struts in a polylactide bioresorbable scaffold: evidence in vivo about the abluminal healing process.
Journal: JACC. Cardiovascular interventions 20120401
Title: Nobori stent shows less vascular inflammation and early recovery of endothelial function compared with Cypher stent.
Journal: JACC. Cardiovascular interventions 20120401
Title: DUrable polymer-based sTent CHallenge of Promus ElemEnt versus ReSolute integrity (DUTCH PEERS): rationale and study design of a randomized multicenter trial in a Dutch all-comers population.
Journal: American heart journal 20120401
Title: ComparisOn of neointimal coVerage betwEen zotaRolimus-eluting stent and everolimus-eluting stent using Optical Coherence Tomography (COVER OCT).
Journal: American heart journal 20120401
Title: Optical coherence tomography (OCT) evaluation after coronary stenting: the 'black hole' and other low OCT signal-intensity areas.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401
Title: Atypical 'black hole' phenomenon after treatment of sirolimus stent restenosis with a paclitaxel-coated balloon.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401
Title: Serial optical coherence tomography imaging of the 'black-hole' phenomenon by intravascular ultrasound following sirolimus-eluting stent implantation.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401
Title: Targeted therapeutics in treatment of children and young adults with solid tumors: an expert survey and review of the literature.
Journal: Klinische Padiatrie 20120401
Title: Rapamycin increases oxidative stress response gene expression in adult stem cells.
Journal: Aging 20120401
Title: Plasmonic photothermic and stem cell therapy of atherosclerotic plaque as a novel nanotool for angioplasty and artery remodeling.
Journal: Rejuvenation research 20120401
Title: [Effect of rapamycin on high glucose-induced autophagy impairment, oxidative stress and premature senescence in rat mesangial cells in vitro].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120401
Title: Drug-eluting vs. bare metal stents for symptomatic vertebral artery stenosis.
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20120401
Title: [Rapamycin inhibits the proliferation of prostate cancer cell line 22RV1 and activity of S6K1].
Journal: Zhonghua nan ke xue = National journal of andrology 20120401
Title: Phase II study of concurrent radiation therapy, temozolomide, and bevacizumab followed by bevacizumab/everolimus as first-line treatment for patients with glioblastoma.
Journal: Clinical advances in hematology & oncology : H&O 20120401
Title: TOR signaling regulates ribosome and tRNA synthesis via LAMMER/Clk and GSK-3 family kinases.
Journal: Molecular cell 20120330
Title: Rapamycin suppresses the recurrent excitatory circuits of dentate gyrus in a mouse model of temporal lobe epilepsy.
Journal: Biochemical and biophysical research communications 20120330
Title: The TOR complex 1 is a direct target of Rho1 GTPase.
Journal: Molecular cell 20120330
Title: Cell biology. Rapamycin paradox resolved.
Journal: Science (New York, N.Y.) 20120330
Title: Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity.
Journal: Science (New York, N.Y.) 20120330
Title: Chronic activation of mTOR complex 1 is sufficient to cause hepatocellular carcinoma in mice.
Journal: Science signaling 20120327
Title: Hyperplexing: a method for higher-order multiplexed quantitative proteomics provides a map of the dynamic response to rapamycin in yeast.
Journal: Science signaling 20120327
Title: Rapid and orthogonal logic gating with a gibberellin-induced dimerization system.
Journal: Nature chemical biology 20120325
Title: Transcription factor Foxo1 represses T-bet-mediated effector functions and promotes memory CD8(+) T cell differentiation.
Journal: Immunity 20120323
Title: Rapamycin promotes autophagy and reduces neural tissue damage and locomotor impairment after spinal cord injury in mice.
Journal: Journal of neurotrauma 20120320
Title: Randomized trial of optimal treatment strategies for in-stent restenosis after drug-eluting stent implantation.
Journal: Journal of the American College of Cardiology 20120320
Title: Rapamycin enhances docetaxel-induced cytotoxicity in a androgen-independent prostate cancer xenograft model by survivin downregulation.
Journal: Biochemical and biophysical research communications 20120316
Title: Single-cell pharmacodynamic monitoring of S6 ribosomal protein phosphorylation in AML blasts during a clinical trial combining the mTOR inhibitor sirolimus and intensive chemotherapy.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120315
Title: Innate and adaptive immune responses are tolerized in chimeras prepared with nonmyeloablative conditioning.
Journal: Transplantation 20120315
Title: Macrophage-induced tumor angiogenesis is regulated by the TSC2-mTOR pathway.
Journal: Cancer research 20120315
Title: Phospho-specific flow: fixating on the target.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120315
Title: Effect of everolimus on left ventricular hypertrophy of de novo kidney transplant recipients: a 1 year, randomized, controlled trial.
Journal: Transplantation 20120315
Title: Ovarian toxicity from sirolimus.
Journal: The New England journal of medicine 20120315
Title: PIK3CA/PTEN mutations and Akt activation as markers of sensitivity to allosteric mTOR inhibitors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120315
Title: Randomized comparison of everolimus-eluting and sirolimus-eluting stents in patients treated with percutaneous coronary intervention: the Scandinavian Organization for Randomized Trials with Clinical Outcome IV (SORT OUT IV).
Journal: Circulation 20120313
Title: Phase II study of everolimus with biomarker exploration in patients with advanced gastric cancer refractory to chemotherapy including fluoropyrimidine and platinum.
Journal: British journal of cancer 20120313
Title: Ridaforolimus in advanced sarcomas: a leap forward or missed opportunity?
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120310
Title: Spatio-temporal manipulation of small GTPase activity at subcellular level and on timescale of seconds in living cells.
Journal: Journal of visualized experiments : JoVE 20120309
Title: Intratumor heterogeneity and branched evolution revealed by multiregion sequencing.
Journal: The New England journal of medicine 20120308
Title: Very late coronary stent thrombosis of a newer-generation everolimus-eluting stent compared with early-generation drug-eluting stents: a prospective cohort study.
Journal: Circulation 20120306
Title: Synergistic anti-tumor effects of RAD001 with MEK inhibitors in neuroendocrine tumors: a potential mechanism of therapeutic limitation of mTOR inhibitor.
Journal: Molecular and cellular endocrinology 20120305
Title: Quantitative multi-modality imaging analysis of a fully bioresorbable stent: a head-to-head comparison between QCA, IVUS and OCT.
Journal: The international journal of cardiovascular imaging 20120301
Title: Rapamycin attenuates the expression of cocaine-induced place preference and behavioral sensitization.
Journal: Addiction biology 20120301
Title: Favorable neointimal coverage in everolimus-eluting stent at 9 months after stent implantation: comparison with sirolimus-eluting stent using optical coherence tomography.
Journal: The international journal of cardiovascular imaging 20120301
Title: Evaluation with in vivo optical coherence tomography and histology of the vascular effects of the everolimus-eluting bioresorbable vascular scaffold at two years following implantation in a healthy porcine coronary artery model: implications of pilot results for future pre-clinical studies.
Journal: The international journal of cardiovascular imaging 20120301
Title: Perioperative rupture of the LIMA graft leading to cardiogenic shock, emergency angiography, and stenting with a polytetrafluoroethylene-covered stent.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301
Title: Decreased risk of stent fracture-related restenosis between paclitaxel-eluting stents and sirolimus eluting stents: results of long-term follow-up.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301
Title: Incomplete arterial healing 8 years after the implantation of sirolimus-eluting stent. In vivo visualization by optical coherence tomography.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301
Title: Resolute Italian study in all comers: immediate and one-year outcomes.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301
Title: Sirolimus-eluting stent fracture detection by three-dimensional optical coherence tomography.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301
Title: Effects of everolimus in combination with sildenafil in monocrotaline-induced pulmonary hypertension in rats.
Journal: Cardiovascular toxicology 20120301
Title: New targeted therapies in pituitary carcinoma resistant to temozolomide.
Journal: Pituitary 20120301
Title: [Topical rapamycin solution to treat multiple facial angiofibromas in a patient with tuberous sclerosis].
Journal: Actas dermo-sifiliograficas 20120301
Title: A phase I study of daily everolimus plus low-dose weekly cisplatin for patients with advanced solid tumors.
Journal: Cancer chemotherapy and pharmacology 20120301
Title: Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition.
Journal: Human molecular genetics 20120301
Title: Withdrawal of proliferation signal inhibitors due to adverse events in the maintenance phase of heart transplantation.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120301
Title: Synergistic activity of rapamycin and dexamethasone in vitro and in vivo in acute lymphoblastic leukemia via cell-cycle arrest and apoptosis.
Journal: Leukemia research 20120301
Title: Erk1/2 MAPK and mTOR signaling sequentially regulates progression through distinct stages of oligodendrocyte differentiation.
Journal: Glia 20120301
Title: [Renal tolerance of targeted therapies].
Journal: Bulletin du cancer 20120301
Title: Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma.
Journal: Neuro-oncology 20120301
Title: Nutritional and hormonal regulation of the TOR effector 4E-binding protein (4E-BP) in the mosquito Aedes aegypti.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120301
Title: Phase I trial of everolimus plus sorafenib for patients with advanced renal cell cancer.
Journal: Clinical genitourinary cancer 20120301
Title: Clinical review: Current scientific rationale for the use of somatostatin analogs and mTOR inhibitors in neuroendocrine tumor therapy.
Journal: The Journal of clinical endocrinology and metabolism 20120301
Title: Role and therapeutic potential of PI3K-mTOR signaling in de novo resistance to BRAF inhibition.
Journal: Pigment cell & melanoma research 20120301
Title: Impairment of object recognition memory by rapamycin inhibition of mTOR in the amygdala or hippocampus around the time of learning or reactivation.
Journal: Behavioural brain research 20120301
Title: Sorafenib, a multikinase inhibitor, is effective in vitro against non-Hodgkin lymphoma and synergizes with the mTOR inhibitor rapamycin.
Journal: American journal of hematology 20120301
Title: Inhibition of MTOR disrupts autophagic flux in podocytes.
Journal: Journal of the American Society of Nephrology : JASN 20120301
Title: Circumferential evaluation of the neointima by optical coherence tomography after ABSORB bioresorbable vascular scaffold implantation: can the scaffold cap the plaque?
Journal: Atherosclerosis 20120301
Title: Rapamycin exerts antifungal activity in vitro and in vivo against Mucor circinelloides via FKBP12-dependent inhibition of Tor.
Journal: Eukaryotic cell 20120301
Title: Sirolimus conversion regimen versus continued calcineurin inhibitors in liver allograft recipients: a randomized trial.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120301
Title: The effects of immunosuppressants on vascular function, systemic oxidative stress and inflammation in rats.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20120301
Title: Safety and efficacy of local periadventitial delivery of sirolimus for improving hemodialysis graft patency: first human experience with a sirolimus-eluting collagen membrane (Coll-R).
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120301
Title: Better stent expansion by two-time inflation of stent balloon and its responsible mechanism.
Journal: Journal of cardiology 20120301
Title: Rapamycin prevents the mutant huntingtin-suppressed GLT-1 expression in cultured astrocytes.
Journal: Acta pharmacologica Sinica 20120301
Title: Polycystic kidney disease: a 2011 update.
Journal: Current opinion in nephrology and hypertension 20120301
Title: mTOR inhibitors and its role in the treatment of head and neck squamous cell carcinoma.
Journal: Current treatment options in oncology 20120301
Title: Long-term kidney allograft function and survival in prednisone-free regimens: tacrolimus/mycophenolate mofetil versus tacrolimus/sirolimus.
Journal: Clinical journal of the American Society of Nephrology : CJASN 20120301
Title: Sirolimus conversion for renal dysfunction in liver transplant recipients: the devil really is in the details….
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120301
Title: Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death.
Journal: Autophagy 20120301
Title: Identification of autophagosome-associated proteins and regulators by quantitative proteomic analysis and genetic screens.
Journal: Molecular & cellular proteomics : MCP 20120301
Title: Comparing outcomes after off-pump coronary artery bypass versus drug-eluting stent in diabetic patients.
Journal: Journal of cardiology 20120301
Title: The haemodialysis arteriovenous graft: is a new era coming?
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120301
Title: Fatal acute pulmonary injury associated with everolimus.
Journal: The Annals of pharmacotherapy 20120301
Title: Improvement in renal function after everolimus introduction and calcineurin inhibitor reduction in maintenance thoracic transplant recipients: the significance of baseline glomerular filtration rate.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120301
Title: Molecular/genetic therapies in ovarian cancer: future opportunities and challenges.
Journal: Clinical obstetrics and gynecology 20120301
Title: Fixing a broken stent.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301
Title: Rapamycin slows aging in mice.
Journal: Cell cycle (Georgetown, Tex.) 20120301
Title: Leptin regulates proliferation and apoptosis of colorectal carcinoma through PI3K/Akt/mTOR signalling pathway.
Journal: Journal of biosciences 20120301
Title: Current status of immunosuppressive agents for solid organ transplantation in children.
Journal: Pediatric transplantation 20120301
Title: Successful resolution of inflammation and increased regulatory T cells in sirolimus-treated post-transplant allograft hepatitis.
Journal: Pediatric transplantation 20120301
Title: Autophagy regulates endoplasmic reticulum stress in ischemic preconditioning.
Journal: Autophagy 20120301
Title: Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy.
Journal: Cell death & disease 20120301
Title: Advances in the treatment of relapsed or refractory Hodgkin's lymphoma.
Journal: The oncologist 20120301
Title: Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging.
Journal: Aging 20120301
Title: mTOR kinase inhibitors as a treatment strategy in hematological malignancies.
Journal: Future medicinal chemistry 20120301
Title: Five-year follow-up of the Sirolimus-Eluting Stents vs Vascular Brachytherapy for Bare Metal In-Stent Restenosis (SISR) trial.
Journal: American heart journal 20120301
Title: Five-year results of the Multicenter Randomized Controlled Open-Label Study of the CYPHER Sirolimus-Eluting Stent in the Treatment of Diabetic Patients with De Novo Native Coronary Artery Lesions (SCORPIUS) study: a German multicenter investigation on the effectiveness of sirolimus-eluting stents in diabetic patients.
Journal: American heart journal 20120301
Title: Comparison of drug-eluting and bare-metal stents for primary percutaneous coronary intervention with or without abciximab in ST-segment elevation myocardial infarction: DEBATER: the Eindhoven reperfusion study.
Journal: JACC. Cardiovascular interventions 20120301
Title: Delamination of abluminal polymer of biolimus-eluting stent.
Journal: JACC. Cardiovascular interventions 20120301
Title: LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patients.
Journal: PLoS genetics 20120301
Title: SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians.
Journal: PLoS genetics 20120301
Title: Rapamycin inhibits lymphatic endothelial cell tube formation by downregulating vascular endothelial growth factor receptor 3 protein expression.
Journal: Neoplasia (New York, N.Y.) 20120301
Title: First report of a novel abluminal groove filled biodegradable polymer rapamycin-eluting stent in de novo coronary artery disease: results of the first in man FIREHAWK trial.
Journal: Chinese medical journal 20120301
Title: Safety and efficacy of cobalt chromium alloy based sirolimus-eluting stent with bioabsorbable polymer in porcine model.
Journal: Chinese medical journal 20120301
Title: [Rapamycin treatment of recurrent autoimmune hemolytic anemia in 28 cases].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20120301
Title: Everolimus as primary immunosuppression in kidney transplantation: experience in conversion from calcineurin inhibitors.
Journal: Transplantation 20120227
Title: Rapamycin reduces clinical signs and neuropathic pain in a chronic model of experimental autoimmune encephalomyelitis.
Journal: Journal of neuroimmunology 20120227
Title: Drug interaction between cyclosporine and mTOR inhibitors in experimental model of chronic cyclosporine nephrotoxicity and pancreatic islet dysfunction.
Journal: Transplantation 20120227
Title: Aberrant activation of the mTOR pathway and anti-tumour effect of everolimus on oesophageal squamous cell carcinoma.
Journal: British journal of cancer 20120227
Title: Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes.
Journal: The Journal of biological chemistry 20120224
Title: Everolimus alters white matter diffusion in tuberous sclerosis complex.
Journal: Neurology 20120221
Title: New therapies for tuber-less sclerosis: white matter matters?
Journal: Neurology 20120221
Title: How many therapeutic options are there for recurrent or metastatic salivary duct carcinoma?
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120220
Title: Inhibition of rapamycin-induced autophagy causes necrotic cell death associated with Bax/Bad mitochondrial translocation.
Journal: Neuroscience 20120217
Title: Post-treatment with rapamycin does not prevent epileptogenesis in the amygdala stimulation model of temporal lobe epilepsy.
Journal: Neuroscience letters 20120216
Title: Akt and p53 are potential mediators of reduced mammary tumor growth by cloroquine and the mTOR inhibitor RAD001.
Journal: Biochemical pharmacology 20120215
Title: Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120215
Title: Randomized phase II trial of sorafenib with temsirolimus or tipifarnib in untreated metastatic melanoma (S0438).
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120215
Title: Breast Cancer: Blocking both driver and escape pathways improves outcomes.
Journal: Nature reviews. Clinical oncology 20120214
Title: MNK2 inhibits eIF4G activation through a pathway involving serine-arginine-rich protein kinase in skeletal muscle.
Journal: Science signaling 20120214
Title: [Proliferation effects of sirolimus, cyclosporine A and mycophenolate mofetil on human transitional cell carcinoma cells].
Journal: Zhonghua yi xue za zhi 20120214
Title: Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation.
Journal: The Journal of biological chemistry 20120210
Title: Treatment of patients with advanced neurofibromatosis type 2 with novel molecularly targeted therapies: from bench to bedside.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120210
Title: Improved insulin sensitivity by rapamycin is associated with reduction of mTOR and S6K1 activities in L6 myotubes.
Journal: Biochemical and biophysical research communications 20120210
Title: Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer.
Journal: The New England journal of medicine 20120209
Title: Sirolimus as primary immunosuppression attenuates allograft vasculopathy with improved late survival and decreased cardiac events after cardiac transplantation.
Journal: Circulation 20120207
Title: Forced degradation studies of rapamycin: identification of autoxidation products.
Journal: Journal of pharmaceutical and biomedical analysis 20120205
Title: [Effect of casamino acid on intergeneric conjugation in rapamycin-producing Streptomyces hygroscopicus ATCC29253].
Journal: Wei sheng wu xue bao = Acta microbiologica Sinica 20120204
Title: Formation of tRNA granules in the nucleus of heat-induced human cells.
Journal: Biochemical and biophysical research communications 20120203
Title: Successful treatment of angiofibromata of tuberous sclerosis complex with rapamycin.
Journal: The Journal of dermatological treatment 20120201
Title: The combination of the novel glycolysis inhibitor 3-BrOP and rapamycin is effective against neuroblastoma.
Journal: Investigational new drugs 20120201
Title: Schedule-dependent inhibition of T-cell lymphoma cells by cotreatment with the mTOR inhibitor everolimus and anticancer drugs.
Journal: Investigational new drugs 20120201
Title: Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging.
Journal: Pediatric blood & cancer 20120201
Title: Aprepitant (Emend) significantly increases sirolimus levels in patients undergoing allogeneic hematopoietic SCT.
Journal: Bone marrow transplantation 20120201
Title: Cardiac tamponade potentially related to sirolimus following cord blood transplantation.
Journal: Bone marrow transplantation 20120201
Title: Sustained clinical safety and efficacy of a biodegradable-polymer coated sirolimus-eluting stent in 'real-world' practice: three-year outcomes of the CREATE (Multi-Center Registry of EXCEL Biodegradable Polymer Drug Eluting Stents) study.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120201
Title: mTOR signaling pathway regulates the IL-12/IL-10 axis in Leishmania donovani infection.
Journal: Medical microbiology and immunology 20120201
Title: Effect of different immunosuppressive regimens on the evolution of distinct metabolic parameters: evidence from the Symphony study.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120201
Title: [Sirolimus-eluting stent displaced fracture: case report and review of the literature].
Journal: Annales de cardiologie et d'angeiologie 20120201
Title: Preparation and influencing factors of sirolimus liposome by supercritical fluid.
Journal: Artificial cells, blood substitutes, and immobilization biotechnology 20120201
Title: [PI3K-AKT-mTOR pathway and cancer].
Journal: Bulletin du cancer 20120201
Title: mTOR inhibition and erythropoiesis: microcytosis or anaemia?
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120201
Title: An international expanded-access programme of everolimus: addressing safety and efficacy in patients with metastatic renal cell carcinoma who progress after initial vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy.
Journal: European journal of cancer (Oxford, England : 1990) 20120201
Title: [Intermittent fever under iatrogenic immunosuppression].
Journal: Der Internist 20120201
Title: Mammalian target of rapamycin (mTOR) inhibitors slow skin carcinogenesis, but impair wound healing.
Journal: The British journal of dermatology 20120201
Title: mTOR as a therapeutic target in patients with gastric cancer.
Journal: International journal of cancer 20120201
Title: mTOR is a selective effector of the radiation therapy response in androgen receptor-positive prostate cancer.
Journal: Endocrine-related cancer 20120201
Title: EGFR- and AKT-mediated reduction in PTEN expression contributes to tyrphostin resistance and is reversed by mTOR inhibition in endometrial cancer cells.
Journal: Molecular and cellular biochemistry 20120201
Title: Antirestenotic mechanisms of everolimus on human coronary artery smooth muscle cells: inhibition of human coronary artery smooth muscle cell proliferation, but not migration.
Journal: Journal of cardiovascular pharmacology 20120201
Title: Rapamycin provides a therapeutic option through inhibition of mTOR signaling in chronic myelogenous leukemia.
Journal: Oncology reports 20120201
Title: Activation of mTOR by human T-cell leukemia virus type 1 Tax is important for the transformation of mouse T cells to interleukin-2-independent growth.
Journal: Cancer science 20120201
Title: Five-year clinical outcome after primary stenting of totally occluded native coronary arteries: a randomised comparison of bare metal stent implantation with sirolimus-eluting stent implantation for the treatment of total coronary occlusions (PRISON II study).
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120201
Title: Pharmacokinetic analysis after implantation of everolimus-eluting self-expanding stents in the peripheral vasculature.
Journal: Journal of vascular surgery 20120201
Title: Insulin-induced mTOR activity exhibits anti-hepatitis C virus activity.
Journal: Molecular medicine reports 20120201
Title: Clinical outcomes in kidney transplant recipients receiving long-term therapy with inhibitors of the mammalian target of rapamycin.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120201
Title: Focal adhesion kinase governs cardiac concentric hypertrophic growth by activating the AKT and mTOR pathways.
Journal: Journal of molecular and cellular cardiology 20120201
Title: Differential mTOR and ERK pathway utilization by effector CD4 T cells suggests combinatorial drug therapy of arthritis.
Journal: Clinical immunology (Orlando, Fla.) 20120201
Title: Novel role of c-jun N-terminal kinase in regulating the initiation of cap-dependent translation.
Journal: International journal of oncology 20120201
Title: Vascular disruption in combination with mTOR inhibition in renal cell carcinoma.
Journal: Molecular cancer therapeutics 20120201
Title: Gene expression profile in response to doxorubicin-rapamycin combined treatment of HER-2-overexpressing human mammary epithelial cell lines.
Journal: Molecular cancer therapeutics 20120201
Title: Successful and cost-efficient replacement of immunoassays by tandem mass spectrometry for the quantification of immunosuppressants in the clinical laboratory.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120201
Title: Sorafenib and Mek inhibition is synergistic in medullary thyroid carcinoma in vitro.
Journal: Endocrine-related cancer 20120201
Title: Tuberous sclerosis complex-associated angiomyolipomas: focus on mTOR inhibition.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20120201
Title: Everolimus: in patients with subependymal giant cell astrocytoma associated with tuberous sclerosis complex.
Journal: Paediatric drugs 20120201
Title: Tregs: application for solid-organ transplantation.
Journal: Current opinion in organ transplantation 20120201
Title: Calorie restriction and rapamycin inhibit MMTV-Wnt-1 mammary tumor growth in a mouse model of postmenopausal obesity.
Journal: Endocrine-related cancer 20120201
Title: New advances in the diagnosis and treatment of autoimmune lymphoproliferative syndrome.
Journal: Current opinion in pediatrics 20120201
Title: Targeting protein synthesis in a Myc/mTOR-driven model of anorexia-cachexia syndrome delays its onset and prolongs survival.
Journal: Cancer research 20120201
Title: Major response to everolimus in melanoma with acquired imatinib resistance.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120201
Title: Randomized comparison of everolimus-eluting versus bare-metal stents in patients with critical limb ischemia and infrapopliteal arterial occlusive disease.
Journal: Journal of vascular surgery 20120201
Title: Mammalian target of rapamycin (mTOR) inhibition reduces cerebral vasospasm following a subarachnoid hemorrhage injury in canines.
Journal: Experimental neurology 20120201
Title: Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia.
Journal: Nature neuroscience 20120201
Title: The risk of skin rash and stomatitis with the mammalian target of rapamycin inhibitor temsirolimus: a systematic review of the literature and meta-analysis.
Journal: European journal of cancer (Oxford, England : 1990) 20120201
Title: Everolimus in metastatic renal cell carcinoma: Subgroup analysis of patients with 1 or 2 previous vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapies enrolled in the phase III RECORD-1 study.
Journal: European journal of cancer (Oxford, England : 1990) 20120201
Title: L-leucine alters pancreatic β-cell differentiation and function via the mTor signaling pathway.
Journal: Diabetes 20120201
Title: Rapalogs in viral cancers.
Journal: Expert opinion on investigational drugs 20120201
Title: The CXCR4 antagonist POL5551 is equally effective as sirolimus in reducing neointima formation without impairing re-endothelialisation.
Journal: Thrombosis and haemostasis 20120201
Title: Intrabiliary rapamycin may slow progression of primary sclerosing cholangitis.
Journal: Alimentary pharmacology & therapeutics 20120201
Title: Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damage.
Journal: Autophagy 20120201
Title: miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1.
Journal: Autophagy 20120201
Title: [Hepatocellular carcinoma: what's new?].
Journal: Deutsche medizinische Wochenschrift (1946) 20120201
Title: Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy.
Journal: Autophagy 20120201
Title: Roles of the mammalian target of rapamycin, mTOR, in controlling ribosome biogenesis and protein synthesis.
Journal: Biochemical Society transactions 20120201
Title: Target of rapamcyin (TOR)-based therapeutics for cardiomyopathy: insights from zebrafish genetics.
Journal: Cell cycle (Georgetown, Tex.) 20120201
Title: Increasingly aggressive endovascular management of tibial artery occlusive disease.
Journal: Journal of vascular surgery 20120201
Title: Creating biodegradable-polymer drug-eluting stents: shortening the duration of polymer and dual antiplatelet therapy while lengthening the follow-up.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120201
Title: Deregulated mTOR-mediated translation in intellectual disability.
Journal: Progress in neurobiology 20120201
Title: Mechanism of edge restenosis after sirolimus-eluting stent implantation.
Journal: The Journal of invasive cardiology 20120201
Title: Topical 0.1% rapamycin for angiofibromas in paediatric patients with tuberous sclerosis: a pilot study of four patients.
Journal: The Australasian journal of dermatology 20120201
Title: Long-term outcome of conversion to sirolimus monotherapy after liver transplant.
Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120201
Title: Sirolimus-eluting stents for the treatment of infrapopliteal arteries in chronic limb ischemia: long-term clinical and angiographic follow-up.
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20120201
Title: Prime time for infrapopliteal drug-eluting stents?
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20120201
Title: Advantages of novel BioMimeTM Sirolimus Eluting Coronary Stent system. Moving towards biomimicry.
Journal: Minerva cardioangiologica 20120201
Title: Comparison of early and late conversion of sirolimus in experimental model of chronic cyclosporine nephropathy.
Journal: Journal of Korean medical science 20120201
Title: Surgical treatment of entrapped intravascular ultrasonography catheter.
Journal: General thoracic and cardiovascular surgery 20120201
Title: Side branch fractional flow reserve measurements after main vessel stenting: a Nordic-Baltic Bifurcation Study III substudy.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120201
Title: One-year outcomes of patients with the zotarolimus-eluting coronary stent: RESOLUTE International Registry.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120201
Title: Calcified in-stent restenosis: a rare cause of dilation failure requiring rotational atherectomy.
Journal: Circulation. Cardiovascular interventions 20120201
Title: OCT-verified neointimal hyperplasia is increased at fracture site in drug-eluting stents.
Journal: JACC. Cardiovascular imaging 20120201
Title: Automated image analysis of nuclear shape: what can we learn from a prematurely aged cell?
Journal: Aging 20120201
Title: Molecular imaging of drug-eluting coronary stents: method development, optimization and selected applications.
Journal: Journal of mass spectrometry : JMS 20120201
Title: Long-term comparison of everolimus- and sirolimus-eluting stents in patients with acute coronary syndromes.
Journal: JACC. Cardiovascular interventions 20120201
Title: No evidence of 'obesity paradox' after treatment with drug-eluting stents in a routine clinical practice: results from the prospective multicenter German DES.DE (German Drug-Eluting Stent) Registry.
Journal: JACC. Cardiovascular interventions 20120201
Title: [Immunogenetic diagnosis of large granular lymphocytic leukemia and therapy by sirolimus].
Journal: Zhongguo shi yan xue ye xue za zhi 20120201
Title: [Effect of granulocyte-macrophage colony-stimulating factor on the mammalian target of sirolimus signaling pathway in the wound of rat].
Journal: Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20120201
Title: [Sirolimus use in heart transplantation recipients with chronic renal dysfunction].
Journal: Zhonghua xin xue guan bing za zhi 20120201
Title: Target of rapamycin (TOR)-based therapy for cardiomyopathy: evidence from zebrafish and human studies.
Journal: Trends in cardiovascular medicine 20120201
Title: Very late stent thrombosis and late target lesion revascularization after sirolimus-eluting stent implantation: five-year outcome of the j-Cypher Registry.
Journal: Circulation 20120131
Title: Very late stent thrombosis and late target lesion revascularization: no end in sight.
Journal: Circulation 20120131
Title: Rapamycin inhibits osteolysis and improves survival in a model of experimental bone metastases.
Journal: Cancer letters 20120128
Title: Saccharomyces cerevisiae Tel2 plays roles in TORC signaling and telomere maintenance that can be mutationally separated.
Journal: Biochemical and biophysical research communications 20120127
Title: Response to 'Sirolimus or paclitaxel drug eluting stent in left main disease: the winner is...'.
Journal: International journal of cardiology 20120126
Title: Influenza virus polymerase confers independence of the cellular cap-binding factor eIF4E for viral mRNA translation.
Journal: Virology 20120120
Title: Rapamycin and glucose-target of rapamycin (TOR) protein signaling in plants.
Journal: The Journal of biological chemistry 20120120
Title: Targeted therapies for renal cell carcinoma: review of adverse event management strategies.
Journal: Journal of the National Cancer Institute 20120118
Title: Optimization of rapamycin-loaded acetalated dextran microparticles for immunosuppression.
Journal: International journal of pharmaceutics 20120117
Title: Activation of mTOR/p70S6 kinase by ANG II inhibits insulin-stimulated endothelial nitric oxide synthase and vasodilation.
Journal: American journal of physiology. Endocrinology and metabolism 20120115
Title: Leucine and arginine regulate trophoblast motility through mTOR-dependent and independent pathways in the preimplantation mouse embryo.
Journal: Developmental biology 20120115
Title: Impact of early conversion from tacrolimus to sirolimus on chronic allograft changes in kidney recipients on rapid steroid withdrawal.
Journal: Transplantation 20120115
Title: Rapamycin combined with TGF-β converts human invariant NKT cells into suppressive Foxp3+ regulatory cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20120115
Title: Facial angiofibromas treated with topical rapamycin: an excellent choice with fast response.
Journal: Dermatology online journal 20120115
Title: Comparison of drug-eluting versus bare-metal stent implantation in ST-elevation myocardial infarction patients with renal insufficiency: results from the national registry in Korea.
Journal: International journal of cardiology 20120112
Title: Dual mTORC1/mTORC2 inhibition diminishes Akt activation and induces Puma-dependent apoptosis in lymphoid malignancies.
Journal: Blood 20120112
Title: CB2 cannabinoid receptors promote neural progenitor cell proliferation via mTORC1 signaling.
Journal: The Journal of biological chemistry 20120106
Title: Hyperpolarized 13C MR spectroscopic imaging can be used to monitor Everolimus treatment in vivo in an orthotopic rodent model of glioblastoma.
Journal: NeuroImage 20120102
Title: Rictor-dependent AKT activation and inhibition of urothelial carcinoma by rapamycin.
Journal: Urologic oncology 20120101
Title: mTOR pathway inhibition in renal cell carcinoma.
Journal: Urologic oncology 20120101
Title: An update on targeted therapy in metastatic renal cell carcinoma.
Journal: Urologic oncology 20120101
Title: Morphological and functional evaluation of the bioresorption of the bioresorbable everolimus-eluting vascular scaffold using IVUS, echogenicity and vasomotion testing at two year follow-up: a patient level insight into the ABSORB A clinical trial.
Journal: The international journal of cardiovascular imaging 20120101
Title: Reproducibility of Shin's method for necrotic core and calcium content in atherosclerotic coronary lesions treated with bioresorbable everolimus-eluting vascular scaffolds using volumetric intravascular ultrasound radiofrequency-based analysis.
Journal: The international journal of cardiovascular imaging 20120101
Title: Pharmacokinetics and pharmacodynamics of mycophenolate sodium (EC-MPS) co-administered with cyclosporine in the early-phase post-kidney transplantation.
Journal: Clinical transplantation 20120101
Title: Long-term effects on renal function of dose-reduced calcineurin inhibitor and sirolimus in cardiac transplant patients.
Journal: Clinical transplantation 20120101
Title: The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models.
Journal: Breast cancer research and treatment 20120101
Title: A case of subacute thrombosis associated with clopidogrel resistance after implantation of a zotarolimus-eluting stent.
Journal: Heart and vessels 20120101
Title: Temsirolimus in combination with carboplatin and paclitaxel in patients with advanced solid tumors: a NCIC-CTG, phase I, open-label dose-escalation study (IND 179).
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20120101
Title: Third in-stent restenosis in sirolimus eluting stents: predictors of the next restenosis.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120101
Title: Pathological features of in-stent restenosis after sirolimus-eluting stent versus bare metal stent placement.
Journal: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 20120101
Title: Rapamycin decreases survivin expression to induce NSCLC cell apoptosis under hypoxia through inhibiting HIF-1α induction.
Journal: Molecular biology reports 20120101
Title: Sirolimus-based regimen is associated with decreased expression of glomerular vascular endothelial growth factor.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120101
Title: Usefulness of preclinical models for assessing the efficacy of late-life interventions for sarcopenia.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20120101
Title: Evaluating rational non-cross-resistant combination therapy in advanced clear cell renal cell carcinoma: combined mTOR and AKT inhibitor therapy.
Journal: Cancer chemotherapy and pharmacology 20120101
Title: Safety and efficacy of temsirolimus in heavily pretreated patients with metastatic renal cell carcinoma.
Journal: Acta oncologica (Stockholm, Sweden) 20120101
Title: The use of sirolimus should be restricted in liver transplantation.
Journal: Journal of hepatology 20120101
Title: Hyperactivation of mTOR critically regulates abnormal osteoclastogenesis in neurofibromatosis Type 1.
Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20120101
Title: Caloric restriction and chronic inflammatory diseases.
Journal: Oral diseases 20120101
Title: Sirolimus--it doesn't deserve its bad Rap(a).
Journal: Journal of hepatology 20120101
Title: Rapamycin reduces oxidative stress in frataxin-deficient yeast cells.
Journal: Mitochondrion 20120101
Title: Is advanced hepatocellular carcinoma amenable of cure by liver transplantation with sorafenib as a neoadjuvant approach plus m-TOR inhibitors monotherapy?
Journal: Journal of surgical oncology 20120101
Title: Erythropoietin mediated bone formation is regulated by mTOR signaling.
Journal: Journal of cellular biochemistry 20120101
Title: S6K inhibition renders cardiac protection against myocardial infarction through PDK1 phosphorylation of Akt.
Journal: The Biochemical journal 20120101
Title: Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin.
Journal: Neurobiology of disease 20120101
Title: GADD34 mediates cytoprotective autophagy in mutant huntingtin expressing cells via the mTOR pathway.
Journal: Experimental cell research 20120101
Title: CD40 blockade combines with CTLA4Ig and sirolimus to produce mixed chimerism in an MHC-defined rhesus macaque transplant model.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120101
Title: Efficacy and safety of sorafenib in combination with mammalian target of rapamycin inhibitors for recurrent hepatocellular carcinoma after liver transplantation.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120101
Title: Everolimus-eluting stents for treatment of chronic total coronary occlusions.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20120101
Title: Clinical long-term outcome after implantation of titanium nitride-oxide coated stents compared with paclitaxel- or sirolimus-eluting stents: propensity-score matched analysis.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101
Title: Four-year clinical follow-up of the ABSORB everolimus-eluting bioresorbable vascular scaffold in patients with de novo coronary artery disease: the ABSORB trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101
Title: Campylobacter jejuni induces colitis through activation of mammalian target of rapamycin signaling.
Journal: Gastroenterology 20120101
Title: Lack of amino acids in mouse hepatocytes in culture induces the selection of preneoplastic cells.
Journal: Cellular signalling 20120101
Title: Sirolimus-based immunosuppression in liver transplantation for hepatocellular carcinoma: a meta-analysis.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120101
Title: Rapamycin causes upregulation of autophagy and impairs islets function both in vitro and in vivo.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120101
Title: Pharmacokinetic drug interaction between AEE788 and RAD001 causing thrombocytopenia in patients with glioblastoma.
Journal: Cancer chemotherapy and pharmacology 20120101
Title: Butyrolactone derivative 3-benzyl-5-((2-nitrophenoxy) methyl)-dihydrofuran-2(3H)-one protects against amyloid-β peptides-induced cytotoxicity in PC12 cells.
Journal: Journal of Alzheimer's disease : JAD 20120101
Title: A theoretical model to characterize the drug release behavior of drug-eluting stents with durable polymer matrix coating.
Journal: Journal of biomedical materials research. Part A 20120101
Title: Effective everolimus treatment of inoperable, life-threatening subependymal giant cell astrocytoma and intractable epilepsy in a patient with tuberous sclerosis complex.
Journal: European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20120101
Title: Impact of calcification on the long-term outcomes of sirolimus-eluting stent implantation: subanalysis of the Cypher Post-Marketing Surveillance Registry.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101
Title: Production of 3-hydroxypropionic acid through propionaldehyde dehydrogenase PduP mediated biosynthetic pathway in Klebsiella pneumoniae.
Journal: Bioresource technology 20120101
Title: Differential regulation of simultaneous antitumor and alloreactive CD8(+) T-cell responses in the same host by rapamycin.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120101
Title: Is there any place for macrolides in mood disorders?
Journal: Medical hypotheses 20120101
Title: Phase II trial of temsirolimus in children with high-grade glioma, neuroblastoma and rhabdomyosarcoma.
Journal: European journal of cancer (Oxford, England : 1990) 20120101
Title: Inhibition of mTOR by rapamycin in the amygdala or hippocampus impairs formation and reconsolidation of inhibitory avoidance memory.
Journal: Neurobiology of learning and memory 20120101
Title: Effect of early conversion from CNI to sirolimus on outcomes in kidney transplant recipients with allograft dysfunction.
Journal: Journal of nephrology 20120101
Title: Three-year follow-up of sirolimus-eluting stents vs. bare metal stents for acute myocardial infarction.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101
Title: Rapamycin induces Bad phosphorylation in association with its resistance to human lung cancer cells.
Journal: Molecular cancer therapeutics 20120101
Title: The PTPN11 loss-of-function mutation Q510E-Shp2 causes hypertrophic cardiomyopathy by dysregulating mTOR signaling.
Journal: American journal of physiology. Heart and circulatory physiology 20120101
Title: Current development of the second generation of mTOR inhibitors as anticancer agents.
Journal: Chinese journal of cancer 20120101
Title: Rapamycin inhibiting Jurkat T cells viability through changing mRNA expression of serine/threonine protein phosphatase 2A.
Journal: Transplant immunology 20120101
Title: RhoA and Rho kinase mediate cyclosporine A and sirolimus-induced barrier tightening in renal proximal tubular cells.
Journal: The international journal of biochemistry & cell biology 20120101
Title: Phase II study of the mammalian target of rapamycin inhibitor ridaforolimus in patients with advanced bone and soft tissue sarcomas.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120101
Title: From node to pathway blockade: lessons learned from targeting mammalian target of rapamycin.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120101
Title: Rapamycin inhibits osteoclast formation in giant cell tumor of bone through the C/EBPβ - MafB axis.
Journal: Journal of molecular medicine (Berlin, Germany) 20120101
Title: Temsirolimus, an mTOR inhibitor, in combination with lower-dose clofarabine as salvage therapy for older patients with acute myeloid leukaemia: results of a phase II GIMEMA study (AML-1107).
Journal: British journal of haematology 20120101
Title: The type 1 insulin-like growth factor receptor (IGF-IR) pathway is mandatory for the follistatin-induced skeletal muscle hypertrophy.
Journal: Endocrinology 20120101
Title: Acquired Omenn-like syndrome, a novel posttransplant autoaggression syndrome reversed by rapamycin.
Journal: Clinical and vaccine immunology : CVI 20120101
Title: Spatial distribution and temporal evolution of scattering centers by optical coherence tomography in the poly(L-lactide) backbone of a bioresorbable vascular scaffold.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101
Title: A randomized, dose-escalation study of subconjunctival and intravitreal injections of sirolimus in patients with diabetic macular edema.
Journal: Ophthalmology 20120101
Title: Exercise modulates microRNAs that affect the PTEN/mTOR pathway in rats after spinal cord injury.
Journal: Experimental neurology 20120101
Title: Mammalian target of rapamycin: a signaling kinase for every aspect of cellular life.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Biochemical and pharmacological inhibition of mTOR by rapamycin and an ATP-competitive mTOR inhibitor.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Evaluation of rapamycin-induced cell death.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Evaluation of mTOR-regulated mRNA translation.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: A genome-wide RNAi screen for polypeptides that alter rpS6 phosphorylation.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Quantitative visualization of autophagy induction by mTOR inhibitors.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Expanding human T regulatory cells with the mTOR-inhibitor rapamycin.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Rapamycin-induced enhancement of vaccine efficacy in mice.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Exploring functional in vivo consequences of the selective genetic ablation of mTOR signaling in T helper lymphocytes.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Evaluating the therapeutic potential of mTOR inhibitors using mouse genetics.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Inhibition of PI3K-Akt-mTOR signaling in glioblastoma by mTORC1/2 inhibitors.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Assessing the function of mTOR in human embryonic stem cells.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Tissue-specific ablation of Tsc1 in pancreatic beta-cells.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: A mouse model of diet-induced obesity and insulin resistance.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Rapamycin as immunosuppressant in murine transplantation model.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Development of ATP-competitive mTOR inhibitors.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Cre8™ coronary stent: preclinical in vivo assessment of a new generation polymer-free DES with Amphilimus™ formulation.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101
Title: Sirolimus-eluting stent vs. everolimus-eluting stent for coronary intervention in patients on chronic hemodialysis.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101
Title: In vivo optical coherence tomography of very late drug-eluting stent thrombosis compared with late in-stent restenosis.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101
Title: Preconditioning donor with a combination of tacrolimus and rapamacyn to decrease ischaemia-reperfusion injury in a rat syngenic kidney transplantation model.
Journal: Clinical and experimental immunology 20120101
Title: Tacrolimus versus cyclosporine for early steroid withdrawal after renal transplantation.
Journal: Journal of nephrology 20120101
Title: mTOR inhibitor-associated proteinuria in kidney transplant recipients.
Journal: Transplantation reviews (Orlando, Fla.) 20120101
Title: Functional characterization of glycine N-methyltransferase and its interactive protein DEPDC6/DEPTOR in hepatocellular carcinoma.
Journal: Molecular medicine (Cambridge, Mass.) 20120101
Title: An unusual cause of cancer mimicry following liver transplantation.
Journal: Annals of hepatology 20120101
Title: Rapamycin activates autophagy in Hutchinson-Gilford progeria syndrome: implications for normal aging and age-dependent neurodegenerative disorders.
Journal: Autophagy 20120101
Title: Sex-specific benefits of sirolimus-eluting stent on long-term outcomes in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: insights from the Multicenter Evaluation of Single High-Dose Bolus Tirofiban Versus Abciximab With Sirolimus-Eluting Stent or Bare-Metal Stent in Acute Myocardial Infarction Study trial.
Journal: American heart journal 20120101
Title: Drug-eluting stents at a crossroads: the good, the bad and the ugly.
Journal: Future cardiology 20120101
Title: A double whammy for aging? Rapamycin extends lifespan and inhibits cancer in inbred female mice.
Journal: Cell cycle (Georgetown, Tex.) 20120101
Title: Repetita iuvant (repeating helps): why another paper on a new stent is important.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101
Title: Five-year clinical follow-up from the MISSION! Intervention Study: sirolimus-eluting stent versus bare metal stent implantation in patients with ST-segment elevation myocardial infarction, a randomised controlled trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101
Title: Predictors of early and late outcomes after everolimus and paclitaxel-eluting coronary stents.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101
Title: Intravascular ultrasound assessment of postprocedural incomplete stent apposition.
Journal: The Journal of invasive cardiology 20120101
Title: mTOR as a target of everolimus in refractory/relapsed Hodgkin lymphoma.
Journal: Current medicinal chemistry 20120101
Title: The sirolimus-eluting Cypher Select coronary stent for the treatment of bare-metal and drug-eluting stent restenosis: insights from the e-SELECT (Multicenter Post-Market Surveillance) registry.
Journal: JACC. Cardiovascular interventions 20120101
Title: Validation of an LC-MS/MS method to determine five immunosuppressants with deuterated internal standards including MPA.
Journal: BMC clinical pharmacology 20120101
Title: [Drug-induced pneumonitis due to sirolimus: an interaction with atorvastatin?].
Journal: Revue des maladies respiratoires 20120101
Title: Rapamycin-induced tumor vasculature remodeling in rhabdomyosarcoma xenografts increases the effectiveness of adjuvant ionizing radiation.
Journal: Journal of pediatric surgery 20120101
Title: A novel application of topical rapamycin formulation, an inhibitor of mTOR, for patients with hypomelanotic macules in tuberous sclerosis complex.
Journal: Archives of dermatology 20120101
Title: An adaptive group sequential phase II design to compare treatments for survival endpoints in rare patient entities.
Journal: Journal of biopharmaceutical statistics 20120101
Title: Reversible acute encephalopathy with mutism, induced by calcineurin inhibitors after renal transplantation.
Journal: Journal of nephrology 20120101
Title: HIV-1 promotes renal tubular epithelial cell protein synthesis: role of mTOR pathway.
Journal: PloS one 20120101
Title: [Immunosuppression in kidney donors with rapamycin and tacrolimus. Proinflammatory cytokine expression].
Journal: Medicina 20120101
Title: Additive effectiveness of everolimus plus tamoxifen therapy in treatment of encapsulating peritoneal sclerosis.
Journal: Renal failure 20120101
Title: Randomized comparison of the efficacy and safety of zotarolimus-eluting stents vs. sirolimus-eluting stents for percutaneous coronary intervention in chronic total occlusion--CAtholic Total Occlusion Study (CATOS) trial.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101
Title: Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells.
Journal: Cell death & disease 20120101
Title: A new path to longevity.
Journal: Scientific American 20120101
Title: Everolimus with reduced-dose cyclosporine versus full-dose cyclosporine and mycophenolate in de novo renal transplant patients: a 2-year single-center experience.
Journal: Transplantation proceedings 20120101
Title: Sirolimus-induced pneumonitis after renal transplantation: a single-center experience.
Journal: Transplantation proceedings 20120101
Title: Trends in the use of immunosuppressive agents by outpatients after renal transplantation at a medical center in southern Taiwan.
Journal: Transplantation proceedings 20120101
Title: Trends in maintenance immunosuppressive drugs used in taiwanese kidney transplant recipients: an analysis of the national health insurance research database.
Journal: Transplantation proceedings 20120101
Title: Statins and stent thrombosis.
Journal: Swiss medical weekly 20120101
Title: First-in-man study of simvastatin-eluting stent in de novo coronary lesions: the SIMVASTENT study.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101
Title: TSC1/2 signaling complex is essential for peripheral naïve CD8+ T cell survival and homeostasis in mice.
Journal: PloS one 20120101
Title: Resveratrol inhibits inflammatory responses via the mammalian target of rapamycin signaling pathway in cultured LPS-stimulated microglial cells.
Journal: PloS one 20120101
Title: Short- and long-term major adverse cardiac events in patients undergoing percutaneous coronary intervention with stenting for acute myocardial infarction complicated by cardiogenic shock.
Journal: Cardiology 20120101
Title: Bullous pemphigoid in a transplant recipient: is this a sign of allograft rejection?
Journal: European journal of dermatology : EJD 20120101
Title: Impact of positive peri-stent vascular remodeling after sirolimus-eluting and paclitaxel-eluting stent implantation on 5-year clinical outcomes: intravascular ultrasound analysis from the Poststent Optimal Stent Expansion Trial multicenter randomized trial.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101
Title: Steve Jobs's cancer. Pancreatic neuroendocrine tumors are becoming more common (the bad news) and also more treatable (the good news).
Journal: Harvard health letter 20120101
Title: Antitumor activities of ATP-competitive inhibitors of mTOR in colon cancer cells.
Journal: BMC cancer 20120101
Title: Delivering hydrophilic and hydrophobic chemotherapeutics simultaneously by magnetic mesoporous silica nanoparticles to inhibit cancer cells.
Journal: International journal of nanomedicine 20120101
Title: Effects of STAT3 gene silencing and rapamycin on apoptosis in hepatocarcinoma cells.
Journal: International journal of medical sciences 20120101
Title: Histological spectrum of pulmonary manifestations in kidney transplant recipients on sirolimus inclusive immunosuppressive regimens.
Journal: Diagnostic pathology 20120101
Title: Delayed mTOR inhibition with low dose of everolimus reduces TGFβ expression, attenuates proteinuria and renal damage in the renal mass reduction model.
Journal: PloS one 20120101
Title: Activation of PI3K/AKT and MAPK pathway through a PDGFRβ-dependent feedback loop is involved in rapamycin resistance in hepatocellular carcinoma.
Journal: PloS one 20120101
Title: Clinical outcomes after treatment of multiple lesions with zotarolimus-eluting versus sirolimus-eluting coronary stents (a SORT OUT III substudy).
Journal: BMC cardiovascular disorders 20120101
Title: [Metastatic breast cancer. Everolimus --a drug delays the progression of the tumor].
Journal: Perspective infirmiere : revue officielle de l'Ordre des infirmieres et infirmiers du Quebec 20120101
Title: The 'Harmonizing Optimal Strategy for Treatment of coronary artery stenosis - sAfety & effectiveneSS of drug-elUting stents & antiplatelet REgimen' (HOST-ASSURE) trial: study protocol for a randomized controlled trial.
Journal: Trials 20120101
Title: A case of Takayasu arteritis with repeated coronary artery restenosis after drug-eluting stent implantation successfully treated with a combination of steroids.
Journal: Internal medicine (Tokyo, Japan) 20120101
Title: Conversion from everolimus with low-exposure cyclosporine to everolimus with mycophenolate sodium maintenance therapy in kidney transplant recipients: a randomized, open-label multicenter study.
Journal: Annals of transplantation 20120101
Title: Rapamycin ameliorates kidney fibrosis by inhibiting the activation of mTOR signaling in interstitial macrophages and myofibroblasts.
Journal: PloS one 20120101
Title: Targeting mTOR pathways in human malignancies.
Journal: Current pharmaceutical design 20120101
Title: Autophagy-lysosomal pathway is involved in lipid degradation in rat liver.
Journal: Physiological research 20120101
Title: Growth hormone improves growth retardation induced by rapamycin without blocking its antiproliferative and antiangiogenic effects on rat growth plate.
Journal: PloS one 20120101
Title: Ex-vivo expanded baboon CD4+ CD25 Hi Treg cells suppress baboon anti-pig T and B cell immune response.
Journal: Xenotransplantation 20120101
Title: Rapamycin conditioning of dendritic cells differentiated from human ES cells promotes a tolerogenic phenotype.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Rapamycin sensitive ROS formation and Na(+)/H(+) exchanger activity in dendritic cells.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Vascular compliance changes of the coronary vessel wall after bioresorbable vascular scaffold implantation in the treated and adjacent segments.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101
Title: Outcomes of patients treated with the everolimus-eluting stent versus the zotarolimus eluting stent in a consecutive cohort of patients at a tertiary medical center.
Journal: Vascular health and risk management 20120101
Title: Inflammation-driven reprogramming of CD4+ Foxp3+ regulatory T cells into pathogenic Th1/Th17 T effectors is abrogated by mTOR inhibition in vivo.
Journal: PloS one 20120101
Title: Novel synergistic antitumor effects of rapamycin with bortezomib on hepatocellular carcinoma cells and orthotopic tumor model.
Journal: BMC cancer 20120101
Title: [Neuroendocrine tumors: the age of targeted therapies].
Journal: Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20120101
Title: Low dose rapamycin exacerbates autoimmune experimental uveitis.
Journal: PloS one 20120101
Title: Onychopathy induced by temsirolimus, a mammalian target of rapamycin inhibitor.
Journal: Dermatology (Basel, Switzerland) 20120101
Title: Preclinical evaluation of injectable sirolimus formulated with polymeric nanoparticle for cancer therapy.
Journal: International journal of nanomedicine 20120101
Title: Simultaneous determination of cyclosporine A, tacrolimus, sirolimus, and everolimus in whole-blood samples by LC-MS/MS.
Journal: TheScientificWorldJournal 20120101
Title: Drosophila poly suggests a novel role for the Elongator complex in insulin receptor-target of rapamycin signalling.
Journal: Open biology 20120101
Title: Genotype-dependent efficacy of a dual PI3K/mTOR inhibitor, NVP-BEZ235, and an mTOR inhibitor, RAD001, in endometrial carcinomas.
Journal: PloS one 20120101
Title: Sirolimus eluting coronary stent implantation in patients on maintenance hemodialysis: the OUCH study (outcome of cypher stent inhemodialysis patients).
Journal: Circulation journal : official journal of the Japanese Circulation Society 20120101
Title: Paradoxical effects of rapamycin on experimental house dust mite-induced asthma.
Journal: PloS one 20120101
Title: Preparation and in vivo evaluation of liposomal everolimus for lung carcinoma and thyroid carcinoma.
Journal: Biological & pharmaceutical bulletin 20120101
Title: Extensive gene-specific translational reprogramming in a model of B cell differentiation and Abl-dependent transformation.
Journal: PloS one 20120101
Title: BOLERO-2 - will this change practice in advanced breast cancer?
Journal: Breast cancer research : BCR 20120101
Title: Comparative vascular responses three months after paclitaxel and everolimus-eluting stent implantation in streptozotocin-induced diabetic porcine coronary arteries.
Journal: Cardiovascular diabetology 20120101
Title: Coronary artery aneurysm after implantation of an endothelial progenitor cell capturing stent.
Journal: Kardiologia polska 20120101
Title: Tumor growth effects of rapamycin on human biliary tract cancer cells.
Journal: European journal of medical research 20120101
Title: Inhibition of chondrosarcoma growth by mTOR inhibitor in an in vivo syngeneic rat model.
Journal: PloS one 20120101
Title: Simultaneous determination of cyclosporine, sirolimus, and tacrolimus in whole blood using liquid chromatography-tandem mass spectrometry.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Autophagy influences maternal mRNA degradation and apoptosis in porcine parthenotes developing in vitro.
Journal: The Journal of reproduction and development 20120101
Title: Everolimus enhances gemcitabine-induced cytotoxicity in bladder-cancer cell lines.
Journal: Journal of toxicology and environmental health. Part A 20120101
Title: Comparison of long-term clinical outcomes between sirolimus-eluting stents and paclitaxel-eluting stents following rotational atherectomy.
Journal: International heart journal 20120101
Title: Occurrence of late acquired peri-stent contrast staining: comparison between sirolimus-eluting stents and everolimus-eluting stents.
Journal: International heart journal 20120101
Title: Successful conversion to everolimus after cytomegalovirus infection in a heart transplant recipient.
Journal: International heart journal 20120101
Title: A case of pancreatic cancer after heart transplantation.
Journal: International heart journal 20120101
Title: Current status and perspectives of targeted therapy in well-differentiated neuroendocrine tumors.
Journal: Oncology 20120101
Title: Sunitinib and everolimus in pancreatic neuroendocrine tumors.
Journal: Tumori 20120101
Title: Protective role of p70S6K in intestinal ischemia/reperfusion injury in mice.
Journal: PloS one 20120101
Title: Sirolimus induced phosphaturia is not caused by inhibition of renal apical sodium phosphate cotransporters.
Journal: PloS one 20120101
Title: Mid-term clinical outcomes of ACS and non-ACS patients treated with everolimus-eluting stents.
Journal: International heart journal 20120101
Title: Nuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation.
Journal: PloS one 20120101
Title: BRAFV600E negatively regulates the AKT pathway in melanoma cell lines.
Journal: PloS one 20120101
Title: Outcomes with various drug eluting or bare metal stents in patients with diabetes mellitus: mixed treatment comparison analysis of 22,844 patient years of follow-up from randomised trials.
Journal: BMJ (Clinical research ed.) 20120101
Title: Rapamycin inhibits proliferation of hemangioma endothelial cells by reducing HIF-1-dependent expression of VEGF.
Journal: PloS one 20120101
Title: Impact of rapamycin on peritoneal fibrosis and transport function.
Journal: Blood purification 20120101
Title: Rapamycin regulates the expression and activity of Krüppel-like transcription factor 2 in human umbilical vein endothelial cells.
Journal: PloS one 20120101
Title: Tolerance induction by exosomes from immature dendritic cells and rapamycin in a mouse cardiac allograft model.
Journal: PloS one 20120101
Title: Impact of small molecules immunosuppressants on P-glycoprotein activity and T-cell function.
Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20120101
Title: Progress in strategies for dosage regimen individualization.
Journal: Current topics in medicinal chemistry 20120101
Title: Amino acids and TOR signaling promote prothoracic gland growth and the initiation of larval molts in the tobacco hornworm Manduca sexta.
Journal: PloS one 20120101
Title: The mTOR inhibitor rapamycin has limited acute anticonvulsant effects in mice.
Journal: PloS one 20120101
Title: [Comparing moderately late results of the application of stents coated with a medicinal antiproliferative agent for the treatment of patients with various forms of coronary heart disease: their efficacy and safety].
Journal: Klinicheskaia meditsina 20120101
Title: The antitumor effect of GDC-0941 alone and in combination with rapamycin in breast cancer cells.
Journal: Chemotherapy 20120101
Title: Impact of CYP3A4*1B and CYP3A5*3 polymorphisms on the pharmacokinetics of cyclosporine and sirolimus in renal transplant recipients.
Journal: Annals of transplantation 20120101
Title: Inhibition of autophagy contributes to ischemic postconditioning-induced neuroprotection against focal cerebral ischemia in rats.
Journal: PloS one 20120101
Title: Flt3L combined with rapamycin promotes cardiac allograft tolerance by inducing regulatory dendritic cells and allograft autophagy in mice.
Journal: PloS one 20120101
Title: Angiogenesis impairment in diabetes: role of methylglyoxal-induced receptor for advanced glycation endproducts, autophagy and vascular endothelial growth factor receptor 2.
Journal: PloS one 20120101
Title: Grape polyphenols inhibit Akt/mammalian target of rapamycin signaling and potentiate the effects of gefitinib in breast cancer.
Journal: Nutrition and cancer 20120101
Title: Low-dose oral sirolimus and the risk of menstrual-cycle disturbances and ovarian cysts: analysis of the randomized controlled SUISSE ADPKD trial.
Journal: PloS one 20120101
Title: Correcting overall survival for the impact of crossover via a rank-preserving structural failure time (RPSFT) model in the RECORD-1 trial of everolimus in metastatic renal-cell carcinoma.
Journal: Journal of biopharmaceutical statistics 20120101
Title: Simultaneous very late stent thrombosis in multiple coronary arteries.
Journal: Texas Heart Institute journal 20120101
Title: Everolimus and sirolimus in combination with cyclosporine have different effects on renal metabolism in the rat.
Journal: PloS one 20120101
Title: Involvement of phosphatidylinositol 3-kinase/Akt pathway in gemcitabine-induced apoptosis-like cell death in insulinoma cell line INS-1.
Journal: Biological & pharmaceutical bulletin 20120101
Title: Nitrogen-responsive regulation of GATA protein family activators Gln3 and Gat1 occurs by two distinct pathways, one inhibited by rapamycin and the other by methionine sulfoximine.
Journal: The Journal of biological chemistry 20111230
Title: Nutrient limitations alter cell division control and chromosome segregation through growth-related kinases and phosphatases.
Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20111227
Title: Associations of ABCB1 3435C>T and IL-10-1082G>A polymorphisms with long-term sirolimus dose requirements in renal transplant patients.
Journal: Transplantation 20111227
Title: [Conversion from calcineurin inhibitors to sirolimus in chronic allograft nephropathy: a 4-year prospective study].
Journal: Zhonghua yi xue za zhi 20111227
Title: The cdk1-cyclin B complex is involved in everolimus triggered resistance in the PC3 prostate cancer cell line.
Journal: Cancer letters 20111226
Title: Defining the role of TORC1/2 in multiple myeloma.
Journal: Blood 20111222
Title: mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells.
Journal: Blood 20111222
Title: Tor complex 1 controls telomere length by affecting the level of Ku.
Journal: Current biology : CB 20111220
Title: Effect of recombinant human SDF-1a on re-endothelialization after sirolimus-eluting stent implantation in rabbit aorta abdominalis.
Journal: Life sciences 20111219
Title: Local persistent hypercoagulability after sirolimus-eluting stent implantation in patients with stable angina.
Journal: International journal of cardiology 20111215
Title: Rapamycin does not control hemophagocytic lymphohistiocytosis in LCMV-infected perforin-deficient mice.
Journal: Pediatric blood & cancer 20111215
Title: Rapamycin for life: a step to immortality.
Journal: Cell cycle (Georgetown, Tex.) 20111215
Title: Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice.
Journal: Cell cycle (Georgetown, Tex.) 20111215
Title: Late-onset proteinuria after antithymocyte globulin induction and de novo sirolimus monotherapy in kidney transplant recipients.
Journal: Transplantation 20111215
Title: Targeting the mTOR/4E-BP pathway in endometrial cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20111215
Title: Rapamycin-induced glucose intolerance: hunger or starvation diabetes.
Journal: Cell cycle (Georgetown, Tex.) 20111215
Title: Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20111210
Title: mTOR inhibitor therapy for patients with carcinoid.
Journal: Lancet (London, England) 20111210
Title: Everolimus plus octreotide long-acting repeatable for the treatment of advanced neuroendocrine tumours associated with carcinoid syndrome (RADIANT-2): a randomised, placebo-controlled, phase 3 study.
Journal: Lancet (London, England) 20111210
Title: Fatty acids suppress autophagic turnover in β-cells.
Journal: The Journal of biological chemistry 20111209
Title: A critical role for GluN2B-containing NMDA receptors in cortical development and function.
Journal: Neuron 20111208
Title: Polymer drug-eluting stents: is the future biodegradable?
Journal: Lancet (London, England) 20111203
Title: Long-term clinical outcomes of biodegradable polymer biolimus-eluting stents versus durable polymer sirolimus-eluting stents in patients with coronary artery disease (LEADERS): 4 year follow-up of a randomised non-inferiority trial.
Journal: Lancet (London, England) 20111203
Title: Phosphorylation of eukaryotic translation initiation factor 4B (EIF4B) by open reading frame 45/p90 ribosomal S6 kinase (ORF45/RSK) signaling axis facilitates protein translation during Kaposi sarcoma-associated herpesvirus (KSHV) lytic replication.
Journal: The Journal of biological chemistry 20111202
Title: Efficacy of RAD001 (everolimus) against advanced gastric cancer with peritoneal dissemination.
Journal: Investigational new drugs 20111201
Title: Long-term stable disease in metastatic renal cell carcinoma: sorafenib sequenced to sunitinib and everolimus: a case study.
Journal: Medical oncology (Northwood, London, England) 20111201
Title: Reactivation of tuberculosis during temsirolimus therapy.
Journal: Investigational new drugs 20111201
Title: Long-term response with everolimus for metastatic renal cell carcinoma refractory to sunitinib.
Journal: Medical oncology (Northwood, London, England) 20111201
Title: Role of the mTOR pathway in LPS-activated monocytes: influence of hypertonic saline.
Journal: The Journal of surgical research 20111201
Title: [Immunosuppressive treatments: mechanisms of action and clinical use].
Journal: Nephrologie & therapeutique 20111201
Title: Serial coronary angioscopic findings of drug-eluting stents implanted in a chronic totally occluded lesion.
Journal: International journal of cardiology 20111201
Title: Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity.
Journal: International journal of cancer 20111201
Title: 3-Dimensional reconstruction of a bifurcation lesion with double wire after implantation of a second generation everolimus-eluting bioresorbable vascular scaffold.
Journal: International journal of cardiology 20111201
Title: Effect of complementary pathway blockade on efficacy of combination enzastaurin and rapamycin.
Journal: Head & neck 20111201
Title: Sirolimus for the treatment of complicated vascular anomalies in children.
Journal: Pediatric blood & cancer 20111201
Title: Stimulation of cardiomyogenesis of embryonic stem cells by nitric oxide downstream of AMP-activated protein kinase and mTOR signaling pathways.
Journal: Stem cells and development 20111201
Title: Sirolimus-eluting stent fracture and aneurysm formation in a young child with a coronary artery bypass graft.
Journal: Pediatric cardiology 20111201
Title: Very late stent thrombosis due to DES fracture: description of a case and review of potential causes.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20111201
Title: Comparison of pharmacokinetics of the limus-eluting stents in Japanese patients.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20111201
Title: Sirolimus for refractory vascular anomalies.
Journal: Pediatric blood & cancer 20111201
Title: Impact of sirolimus, tacrolimus and mycophenolate mofetil on osteoclastogenesis--implications for post-transplantation bone disease.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111201
Title: Immunological aspects of allogeneic and autologous mesenchymal stem cell therapies.
Journal: Human gene therapy 20111201
Title: Evaluation of the MassTrak Immunosuppressant XE Kit for the determination of everolimus and cyclosporin A in human whole blood employing isotopically labeled internal standards.
Journal: Clinical chemistry and laboratory medicine 20111201
Title: Steroid or tacrolimus withdrawal in renal transplant recipients using sirolimus.
Journal: International urology and nephrology 20111201
Title: Inhibitors of mTOR overcome drug resistance from topoisomerase II inhibitors in solid tumors.
Journal: Cancer letters 20111201
Title: m-TOR inhibitors: what role in liver transplantation?
Journal: Journal of hepatology 20111201
Title: Comparison of zotarolimus- versus everolimus-eluting stents in the treatment of coronary bifurcation lesions.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20111201
Title: Sequence therapy in patients with metastatic renal cell carcinoma: comparison of common targeted treatment options following failure of receptor tyrosine kinase inhibitors.
Journal: European urology 20111201
Title: Inhibition of induced autophagy increases apoptosis of Nara-H cells.
Journal: International journal of oncology 20111201
Title: The activation state of the inositol 1,4,5-trisphosphate receptor regulates the velocity of intracellular Ca2+ waves in bovine aortic endothelial cells.
Journal: Journal of cellular biochemistry 20111201
Title: Combining mTor inhibitors with rapamycin-resistant T cells: a two-pronged approach to tumor elimination.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20111201
Title: TGF-β1 mediates sirolimus and cyclosporine A-induced alteration of barrier function in renal epithelial cells via a noncanonical ERK1/2 signaling pathway.
Journal: American journal of physiology. Renal physiology 20111201
Title: Three-year clinical outcome with the Endeavor™ zotarolimus-eluting stent in primary percutaneous coronary intervention for ST elevation myocardial infarction: the Endeavor™ primary PCI study (E-PPCI).
Journal: Journal of interventional cardiology 20111201
Title: Renal function in children with heart transplantation after switching to CNI-free immunosuppression with everolimus.
Journal: Pediatric transplantation 20111201
Title: mTOR: A pathogenic signaling pathway in developmental brain malformations.
Journal: Trends in molecular medicine 20111201
Title: Therapeutic value of prenatal rapamycin treatment in a mouse brain model of tuberous sclerosis complex.
Journal: Human molecular genetics 20111201
Title: Multi-Link Vision stent vs. first-generation drug-eluting stents: systematic review and meta-analysis.
Journal: QJM : monthly journal of the Association of Physicians 20111201
Title: Everolimus in combination with pemetrexed in patients with advanced non-small cell lung cancer previously treated with chemotherapy: a phase I study using a novel, adaptive Bayesian dose-escalation model.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20111201
Title: Involvement of the mammalian target of rapamycin signaling in the antidepressant-like effect of group II metabotropic glutamate receptor antagonists.
Journal: Neuropharmacology 20111201
Title: Rapamycin protects against middle cerebral artery occlusion induced focal cerebral ischemia in rats.
Journal: Behavioural brain research 20111201
Title: Preclinical testing of PI3K/AKT/mTOR signaling inhibitors in a mouse model of ovarian endometrioid adenocarcinoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20111201
Title: Rapamycin decreases airway remodeling and hyperreactivity in a transgenic model of noninflammatory lung disease.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20111201
Title: CNI induced Th17/Treg imbalance and susceptibility to renal dysfunction in renal transplantation.
Journal: International immunopharmacology 20111201
Title: Performance of everolimus-eluting versus paclitaxel-eluting coronary stents in small vessels: results from the SPIRIT III and SPIRIT IV clinical trials.
Journal: Journal of interventional cardiology 20111201
Title: Expression of yeast high mobility group protein HMO1 is regulated by TOR signaling.
Journal: Gene 20111201
Title: [Lymphangioleiomyomatosis: new therapeutic approaches].
Journal: Archivos de bronconeumologia 20111201
Title: Rapamycin suppresses self-renewal and vasculogenic potential of stem cells isolated from infantile hemangioma.
Journal: The Journal of investigative dermatology 20111201
Title: Pregnancy under everolimus-based immunosuppression.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20111201
Title: SYNTAX score and Clinical SYNTAX score as predictors of very long-term clinical outcomes in patients undergoing percutaneous coronary interventions: a substudy of SIRolimus-eluting stent compared with pacliTAXel-eluting stent for coronary revascularization (SIRTAX) trial.
Journal: European heart journal 20111201
Title: Do wound complications or lymphoceles occur more often in solid organ transplant recipients on mTOR inhibitors? A systematic review of randomized controlled trials.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20111201
Title: Late withdrawal of calcineurin inhibitors and switch to mTOR inhibitors--beneficial or too late?
Journal: Pediatric transplantation 20111201
Title: Integration of diffusion-weighted MRI data and a simple mathematical model to predict breast tumor cellularity during neoadjuvant chemotherapy.
Journal: Magnetic resonance in medicine 20111201
Title: Comparison of zotarolimus-eluting stents versus sirolimus-eluting stents versus paclitaxel-eluting stents for primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction: results from the Korean Multicentre Endeavor (KOMER) acute myocardial infarction (AMI) trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111201
Title: Focused ultrasound-mediated drug delivery from microbubbles reduces drug dose necessary for therapeutic effect on neointima formation--brief report.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20111201
Title: Enhanced delivery of rapamycin by V156K-apoA-I high-density lipoprotein inhibits cellular proatherogenic effects and senescence and promotes tissue regeneration.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20111201
Title: Air-liquid biofilm formation is dependent on ammonium depletion in a Saccharomyces cerevisiae flor strain.
Journal: Yeast (Chichester, England) 20111201
Title: Neuronal Nogo-A regulates glutamate receptor subunit expression in hippocampal neurons.
Journal: Journal of neurochemistry 20111201
Title: Chromogranin A and neuron-specific enolase as prognostic markers in patients with advanced pNET treated with everolimus.
Journal: The Journal of clinical endocrinology and metabolism 20111201
Title: Rapamycin reduces reactive oxygen species in cultured human corneal endothelial cells.
Journal: Current eye research 20111201
Title: Targeted therapy in sarcomas: mammalian target of rapamycin inhibitors from bench to bedside.
Journal: Expert opinion on investigational drugs 20111201
Title: Rapamycin attenuates airway hyperreactivity, goblet cells, and IgE in experimental allergic asthma.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20111201
Title: The metabolic and toxicological considerations for mTOR inhibitors in the treatment of hepatocarcinoma.
Journal: Expert opinion on drug metabolism & toxicology 20111201
Title: Comprehensive intravascular ultrasound assessment of stent area and its impact on restenosis and adverse cardiac events in 403 patients with unprotected left main disease.
Journal: Circulation. Cardiovascular interventions 20111201
Title: Infantile hemangioma research: looking backward and forward.
Journal: The Journal of investigative dermatology 20111201
Title: Expression pattern and functions of autophagy-related gene atg5 in zebrafish organogenesis.
Journal: Autophagy 20111201
Title: Kinetic nomograms assist individualization of drug regimens.
Journal: Clinical pharmacokinetics 20111201
Title: Sirolimus in solid organ transplantation: current therapies and new frontiers.
Journal: Immunotherapy 20111201
Title: Is there a critical period for mossy fiber sprouting in a mouse model of temporal lobe epilepsy?
Journal: Epilepsia 20111201
Title: Autophagy in atherosclerosis: a potential drug target for plaque stabilization.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20111201
Title: TFEB, a novel mTORC1 effector implicated in lysosome biogenesis, endocytosis and autophagy.
Journal: Cell cycle (Georgetown, Tex.) 20111201
Title: CDNA cloning and characterization of S6 kinase and its effect on yolk protein gene expression in the oriental fruit fly Bactrocera dorsalis (Hendel).
Journal: Archives of insect biochemistry and physiology 20111201
Title: Bifurcation stenting with a provisional T strategy: drug eluting stent type does matter.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20111201
Title: Rationale and design of the EXAMINATION trial: a randomised comparison between everolimus-eluting stents and cobalt-chromium bare-metal stents in ST-elevation myocardial infarction.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111201
Title: Observations on enhanced port wine stain blanching induced by combined pulsed dye laser and rapamycin administration.
Journal: Lasers in surgery and medicine 20111201
Title: Anti-inflammatory and anti-fibrotic effects of sirolimus on bleomycin-induced pulmonary fibrosis in rats.
Journal: Clinical and investigative medicine. Medecine clinique et experimentale 20111201
Title: [Conversion from a calcineurin inhibitor to a sirolimus-based therapy after renal transplantation - An update of existing recommendations].
Journal: Deutsche medizinische Wochenschrift (1946) 20111201
Title: Deoxyribose protects against rapamycin-induced cytotoxicity in colorectal cancer cells in vitro.
Journal: Nucleosides, nucleotides & nucleic acids 20111201
Title: [Antihormonal therapy in breast cancer and mTOR inhibitors].
Journal: Bulletin du cancer 20111201
Title: Activation of mTOR signaling in medullary and aggressive papillary thyroid carcinomas.
Journal: Surgery 20111201
Title: Risk of target lesion failure in relationship to vessel angiographic geometry and stent conformability using the second generation of drug-eluting stents.
Journal: American heart journal 20111201
Title: Outcomes in patients undergoing multivessel percutaneous coronary intervention using sirolimus-eluting stents: a report from the e-SELECT registry.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111201
Title: Coronary pseudoaneurysm in a non-polymer drug-eluting stent: a rare entity.
Journal: Asian cardiovascular & thoracic annals 20111201
Title: Allosteric activation of kinases: design and application of RapR kinases.
Journal: Current protocols in cell biology 20111201
Title: Better actual 10-year renal transplant outcomes of 80% reduced cyclosporine exposure with sirolimus base therapy compared with full cyclosporine exposure without or with concomittant sirolimus treatment.
Journal: Transplantation proceedings 20111201
Title: Impact of the conversion of the immunosuppressive regimen from prograf to advagraf or to sirolimus in long-term stable liver transplant recipients: indications, safety, and outcome.
Journal: Transplantation proceedings 20111201
Title: Lipid profile changes during the first year after kidney transplantation: risk factors and influence of the immunosuppressive drug regimen.
Journal: Transplantation proceedings 20111201
Title: Oxidative stress indices in rats under immunosuppression.
Journal: Transplantation proceedings 20111201
Title: Stent area by intravascular ultrasound and outcomes in left main intervention with drug-eluting stents: small stents, more events.
Journal: Circulation. Cardiovascular interventions 20111201
Title: Head-to-head comparison of the neointimal response between metallic and bioresorbable everolimus-eluting scaffolds using optical coherence tomography.
Journal: JACC. Cardiovascular interventions 20111201
Title: Serial in vivo intravascular ultrasound-based echogenicity changes of everolimus-eluting bioresorbable vascular scaffold during the first 12 months after implantation insights from the ABSORB B trial.
Journal: JACC. Cardiovascular interventions 20111201
Title: A new era of prospective real-world safety evaluation primary report of XIENCE V USA (XIENCE V Everolimus Eluting Coronary Stent System condition-of-approval post-market study).
Journal: JACC. Cardiovascular interventions 20111201
Title: Mechanism of activation of AMPK and upregulation of OGG1 by rapamycin in cancer cells.
Journal: Oncotarget 20111201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: [What's new in dermatological therapy?].
Journal: Annales de dermatologie et de venereologie 20111201
Title: Repetitive stent fractures with diffuse coronary artery microaneurysm formation--sirolimus eluting stent hypersensitivity?
Journal: Acta clinica Croatica 20111201
Title: Sirolimus and tacrolimus as immune prophylaxis compared to cyclosporine with or without methotrexate in patients undergoing allogeneic haematopoietic stem cell transplantation for non-malignant disorders.
Journal: European journal of haematology 20111201
Title: Combining an EGFR directed tyrosine kinase inhibitor with autophagy-inducing drugs: a beneficial strategy to combat non-small cell lung cancer.
Journal: Cancer letters 20111128
Title: Everolimus prevents endomyocardial remodeling after heart transplantation.
Journal: Transplantation 20111127
Title: Treatment of everolimus-resistant metastatic renal cell carcinoma with VEGF-targeted therapies.
Journal: British journal of cancer 20111122
Title: Small-molecule control of protein degradation using split adaptors.
Journal: ACS chemical biology 20111118
Title: Chemical tools for studying directed cell migration.
Journal: ACS chemical biology 20111118
Title: microRNA-101 is a potent inhibitor of autophagy.
Journal: The EMBO journal 20111116
Title: Phase 1/2 study of everolimus in advanced hepatocellular carcinoma.
Journal: Cancer 20111115
Title: Stent-related cardiac events beyond three years after implantation of the sirolimus-eluting stent (from the EVASTENT Patients).
Journal: The American journal of cardiology 20111115
Title: The role of skeletal muscle mTOR in the regulation of mechanical load-induced growth.
Journal: The Journal of physiology 20111115
Title: Nonobese diabetic natural killer cells: a barrier to allogeneic chimerism that can be reduced by rapamycin.
Journal: Transplantation 20111115
Title: Decreased lymphangiogenesis and lymph node metastasis by mTOR inhibition in head and neck cancer.
Journal: Cancer research 20111115
Title: Discovery and SAR exploration of a novel series of imidazo[4,5-b]pyrazin-2-ones as potent and selective mTOR kinase inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20111115
Title: High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1.
Journal: Cell cycle (Georgetown, Tex.) 20111115
Title: Five-year outcomes of sirolimus-eluting versus paclitaxel-eluting stents: a propensity matched study: clinical evidence of late catch-up?
Journal: International journal of cardiology 20111103
Title: Turn motif phosphorylation negatively regulates activation loop phosphorylation in Akt.
Journal: Oncogene 20111103
Title: Nucleocytoplasmic localization of p70 S6K1, but not of its isoforms p85 and p31, is regulated by TSC2/mTOR.
Journal: Oncogene 20111103
Title: 'Sirolimus or paclitaxel drug eluting stent in left main disease: the winner is... '.
Journal: International journal of cardiology 20111103
Title: FRET detection of calmodulin binding to the cardiac RyR2 calcium release channel.
Journal: Biophysical journal 20111102
Title: Acute myocardial infarction related to very late sirolimus-eluting stent thrombosis 6 months after discontinuation of dual antiplatelet therapy.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20111101
Title: Effect of intravascular ultrasound-guided adjuvant high-pressure non-compliant balloon post-dilation after drug-eluting stent implantation.
Journal: Heart and vessels 20111101
Title: Utility of myocardial fractional flow reserve for prediction of restenosis following sirolimus-eluting stent implantation.
Journal: Heart and vessels 20111101
Title: Efficacy of paclitaxel-eluting stent implantation in hemodialysis patients.
Journal: Heart and vessels 20111101
Title: TGFβ- and bleomycin-induced extracellular matrix synthesis is mediated through Akt and mammalian target of rapamycin (mTOR).
Journal: Journal of cellular physiology 20111101
Title: [Association of post-transplant lymphoproliferative disease and visceral leishmaniasis after kidney transplantation].
Journal: Nephrologie & therapeutique 20111101
Title: Low-dose sirolimus combined with angiotensin-converting enzyme inhibitor and statin stabilizes renal function and reduces glomerular proliferation in poor prognosis IgA nephropathy.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111101
Title: Influence of MRP2 on MPA pharmacokinetics in renal transplant recipients-results of the Pharmacogenomic Substudy within the Symphony Study.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111101
Title: Subconjunctival sirolimus in the treatment of diabetic macular edema.
Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20111101
Title: Autophagy induced by rapamycin and carbon-starvation have distinct proteome profiles in Aspergillus nidulans.
Journal: Biotechnology and bioengineering 20111101
Title: Chronic hypoxia-induced alterations of key enzymes of glucose oxidative metabolism in developing mouse liver are mTOR dependent.
Journal: Molecular and cellular biochemistry 20111101
Title: Differences in drug-eluting stents used in coronary artery disease.
Journal: The American journal of the medical sciences 20111101
Title: Activation of the phosphatidylinositol 3'-kinase/AKT pathway in neuroblastoma and its regulation by thioredoxin 1.
Journal: Human pathology 20111101
Title: mTOR signaling in polycystic kidney disease.
Journal: Trends in molecular medicine 20111101
Title: Identification of cancer stem cells in human gastrointestinal carcinoid and neuroendocrine tumors.
Journal: Gastroenterology 20111101
Title: Cytomegalovirus incidence between everolimus versus mycophenolate in de novo renal transplants: pooled analysis of three clinical trials.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20111101
Title: Hydrogel containing L-valine residues as a platform for cisplatin chemotherapy.
Journal: Colloids and surfaces. B, Biointerfaces 20111101
Title: The role of pre-conversion glomerular filtration rate in predicting long-term renal function after conversion to proliferation signal inhibitors in long-term heart transplant recipients.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20111101
Title: Global and threshold-free Transcriptional Regulatory Networks reconstruction through integrating ChIP-Chip and expression data.
Journal: Current protein & peptide science 20111101
Title: Multimodal biomarker investigation on efficacy and mechanism of action for the mammalian target of rapamycin inhibitor, temsirolimus, in a preclinical mammary carcinoma OncoMouse model: a translational medicine study in support for early clinical development.
Journal: The Journal of pharmacology and experimental therapeutics 20111101
Title: Comparison of angioscopic findings and three-year cardiac events between sirolimus-eluting stent and bare-metal stent in acute myocardial infarction.
Journal: The American journal of cardiology 20111101
Title: Monitoring of mycophenolic acid and kidney function during combined immunosuppressive therapy.
Journal: Clinical chemistry and laboratory medicine 20111101
Title: Hot-topic debate on hepatitis C virus: the type of immunosuppression matters.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20111101
Title: Outcome of sirolimus-eluting versus zotarolimus-eluting coronary stent implantation in patients with and without diabetes mellitus (a SORT OUT III Substudy).
Journal: The American journal of cardiology 20111101
Title: Rapamycin protects against dominant negative-HNF1A-induced apoptosis in INS-1 cells.
Journal: Apoptosis : an international journal on programmed cell death 20111101
Title: mTORC1 activation triggers the unfolded protein response in podocytes and leads to nephrotic syndrome.
Journal: Laboratory investigation; a journal of technical methods and pathology 20111101
Title: Elimination of norovirus in a chronic carrier under immunosuppression after heart transplantation--effect of everolimus.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20111101
Title: Rapamycin suppresses axon sprouting by somatostatin interneurons in a mouse model of temporal lobe epilepsy.
Journal: Epilepsia 20111101
Title: Calcineurin inhibitor minimization using sirolimus leads to improved renal function in pediatric heart transplant recipients.
Journal: Pediatric transplantation 20111101
Title: Calcineurin inhibitors in kidney transplantation: friend or foe?
Journal: Current opinion in nephrology and hypertension 20111101
Title: A phase I trial of liposomal doxorubicin, bevacizumab, and temsirolimus in patients with advanced gynecologic and breast malignancies.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20111101
Title: Emerging roles for mammalian target of rapamycin inhibitors in the treatment of solid tumors and hematological malignancies.
Journal: Current opinion in oncology 20111101
Title: Systemic inhibition of the mammalian target of rapamycin (mTOR) pathway reduces neuropathic pain in mice.
Journal: Pain 20111101
Title: Immunosuppressant regimen based on sirolimus decreases aortic stiffness in renal transplant recipients in comparison to cyclosporine.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20111101
Title: Role of everolimus in pancreatic neuroendocrine tumors.
Journal: Expert review of anticancer therapy 20111101
Title: Sirolimus drug-eluting, hydrogel-impregnated polypropylene mesh reduces intra-abdominal adhesion formation in a mouse model.
Journal: Surgery 20111101
Title: Identifying inhibitors of epithelial-mesenchymal transition by connectivity map-based systems approach.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20111101
Title: Limiting hepatitis C virus progression in liver transplant recipients using sirolimus-based immunosuppression.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20111101
Title: Sirolimus is coming of age.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20111101
Title: Clinical outcome of B2/C type isolated proximal LAD disease treated with drug-eluting stents.
Journal: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20111101
Title: Inhibition of the mammalian target of rapamycin blocks epilepsy progression in NS-Pten conditional knockout mice.
Journal: Epilepsia 20111101
Title: Autophagy and the evasion of host defense: a new variation on the theme for Burkholderia cepacia?
Journal: Autophagy 20111101
Title: Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis.
Journal: Autophagy 20111101
Title: Sirolimus in pediatric renal transplantation.
Journal: Pediatric transplantation 20111101
Title: Sirolimus as renal and immunological rescue agent in pediatric liver transplant recipients.
Journal: Pediatric transplantation 20111101
Title: In situ quantitative imaging of cellular lipids using molecular sensors.
Journal: Nature chemistry 20111101
Title: The three year follow-up of the randomised 'all-comers' trial of a biodegradable polymer biolimus-eluting stent versus permanent polymer sirolimus-eluting stent (LEADERS).
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111101
Title: mTOR kinase inhibition results in oocyte loss characterized by empty follicles in human ovarian cortical strips cultured in vitro.
Journal: Fertility and sterility 20111101
Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.
Journal: Nature biotechnology 20111101
Title: [Second line AUO (Working Group Urological Oncology) study AB 35/09 on metastasized urothelial carcinoma. Phase II study with RAD001 in combination with paclitaxel for patients with metastasized urothelial carcinoma of the urinary bladder after failure of platinum-based chemotherapy (CRAD001)].
Journal: Der Urologe. Ausg. A 20111101
Title: Successful treatment of a late presentation exercise-induced spontaneous left anterior descending artery dissection.
Journal: The Journal of invasive cardiology 20111101
Title: The Spanish experience with hand, forearm, and arm transplantation.
Journal: Hand clinics 20111101
Title: [Management of metastatic neuroendocrine tumors].
Journal: Annales de pathologie 20111101
Title: Plant TOR signaling components.
Journal: Plant signaling & behavior 20111101
Title: Statistical analysis of noncommensurate multiple outcomes.
Journal: Circulation. Cardiovascular quality and outcomes 20111101
Title: Everolimus-induced loss of wound strength can be prevented by a short postoperative delay in its administration.
Journal: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20111101
Title: Long-term tissue coverage of a biodegradable polylactide polymer-coated biolimus-eluting stent: comparative sequential assessment with optical coherence tomography until complete resorption of the polymer.
Journal: American heart journal 20111101
Title: Mechanisms of very late stent thrombosis after drug-eluting stent implantation: findings from coronary angioscopy and optical coherence tomography.
Journal: JACC. Cardiovascular imaging 20111101
Title: Short-term immunossupressive treatment of the donor does not prevent ischemia-reperfusion kidney damage in the rat.
Journal: Transplantation proceedings 20111101
Title: De novo use of everolimus with elimination or minimization of cyclosporine in renal transplant recipients.
Journal: Transplantation proceedings 20111101
Title: Cost-effectiveness analysis of the early conversion of tacrolimus to mammalian target of rapamycin inhibitors in patients with renal transplantation.
Journal: Transplantation proceedings 20111101
Title: Impact of lesion length and vessel size on clinical outcomes after percutaneous coronary intervention with everolimus- versus paclitaxel-eluting stents pooled analysis from the SPIRIT (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) and COMPARE (Second-generation everolimus-eluting and paclitaxel-eluting stents in real-life practice) Randomized Trials.
Journal: JACC. Cardiovascular interventions 20111101
Title: Second-generation everolimus-eluting stents and the beat goes on?
Journal: JACC. Cardiovascular interventions 20111101
Title: Yeast-like chronological senescence in mammalian cells: phenomenon, mechanism and pharmacological suppression.
Journal: Aging 20111101
Title: The reverse, but coordinated, roles of Tor2 (TORC1) and Tor1 (TORC2) kinases for growth, cell cycle and separase-mediated mitosis in Schizosaccharomyces pombe.
Journal: Open biology 20111101
Title: Rapamycin passes the torch: a new generation of mTOR inhibitors.
Journal: Nature reviews. Drug discovery 20111031
Title: Unprotected left main stenting with a second-generation drug-eluting stent: one-year outcomes of the LEMAX Pilot study.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111030
Title: Rapamycin sensitive mTOR activation mediates nerve growth factor (NGF) induced cell migration and pro-survival effects against hydrogen peroxide in retinal pigment epithelial cells.
Journal: Biochemical and biophysical research communications 20111028
Title: Everolimus-eluting versus sirolimus-eluting stents in patients undergoing percutaneous coronary intervention: the EXCELLENT (Efficacy of Xience/Promus Versus Cypher to Reduce Late Loss After Stenting) randomized trial.
Journal: Journal of the American College of Cardiology 20111025
Title: Head-to-head randomized comparisons of limus-eluting coronary stents: pursuing excellence or flying too high?
Journal: Journal of the American College of Cardiology 20111025
Title: Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria.
Journal: European journal of histochemistry : EJH 20111019
Title: Results of a prospective randomized trial of sirolimus conversion in kidney transplant recipients on early corticosteroid withdrawal.
Journal: Transplantation 20111015
Title: Switching from calcineurin inhibitors to Mammalian target of rapamycin inhibitors--finally caught the right wave?
Journal: Transplantation 20111015
Title: mTOR in podocyte function: is rapamycin good for diabetic nephropathy?
Journal: Cell cycle (Georgetown, Tex.) 20111015
Title: Impact of the everolimus-eluting stent on stent thrombosis: a meta-analysis of 13 randomized trials.
Journal: Journal of the American College of Cardiology 20111004
Title: Evaluation of the second generation of a bioresorbable everolimus-eluting vascular scaffold for the treatment of de novo coronary artery stenosis: 12-month clinical and imaging outcomes.
Journal: Journal of the American College of Cardiology 20111004
Title: The magic of disappearing stents.
Journal: Journal of the American College of Cardiology 20111004
Title: North Central Cancer Treatment Group Phase I trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme.
Journal: International journal of radiation oncology, biology, physics 20111001
Title: Assessment of the serial changes of vessel wall contents in atherosclerotic coronary lesion with bioresorbable everolimus-eluting vascular scaffolds using Shin's method: an IVUS study.
Journal: The international journal of cardiovascular imaging 20111001
Title: Weekly administration of temsirolimus for heavily pretreated patients with clear cell carcinoma of the ovary: a report of six cases.
Journal: International journal of clinical oncology 20111001
Title: In vivo therapeutic efficacy of intra-renal CD40 silencing in a model of humoral acute rejection.
Journal: Gene therapy 20111001
Title: Natural history, management and pharmacokinetics of everolimus-induced-oral ulcers: insights into compliance issues.
Journal: European journal of cancer (Oxford, England : 1990) 20111001
Title: Evaluation of the effects of the flavonoid apigenin on apoptotic pathway gene expression on the colon cancer cell line (HT29).
Journal: Journal of medicinal food 20111001
Title: Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells.
Journal: Aging cell 20111001
Title: Long-term response in advanced bladder cancer involving the use of temsirolimus and vinflunine after platin resistance.
Journal: Anti-cancer drugs 20111001
Title: Beclin 1-independent autophagy contributes to apoptosis in cortical neurons.
Journal: Autophagy 20111001
Title: Myxoma virus combined with rapamycin treatment enhances adoptive T cell therapy for murine melanoma brain tumors.
Journal: Cancer immunology, immunotherapy : CII 20111001
Title: Tissue coverage of a hydrophilic polymer-coated zotarolimus-eluting stent vs. a fluoropolymer-coated everolimus-eluting stent at 13-month follow-up: an optical coherence tomography substudy from the RESOLUTE All Comers trial.
Journal: European heart journal 20111001
Title: A topical combination of rapamycin and tacrolimus for the treatment of angiofibroma due to tuberous sclerosis complex (TSC): a pilot study of nine Japanese patients with TSC of different disease severity.
Journal: The British journal of dermatology 20111001
Title: Treatment of facial angiofibromas with topical application of oral rapamycin solution (1mgmL(-1) ) in two patients with tuberous sclerosis.
Journal: The British journal of dermatology 20111001
Title: Enhanced cellular uptake and in vivo pharmacokinetics of rapamycin-loaded cubic phase nanoparticles for cancer therapy.
Journal: Acta biomaterialia 20111001
Title: A ticking time bomb?: a case report of very late stent thrombosis more than 2 years after fracture of a Cypher stent.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20111001
Title: Efficacy of re-challenging metastatic renal cell carcinoma with mTOR inhibitors.
Journal: Acta oncologica (Stockholm, Sweden) 20111001
Title: Phase II trial of the mTOR inhibitor, temsirolimus and evaluation of circulating tumor cells and tumor biomarkers in persistent and recurrent epithelial ovarian and primary peritoneal malignancies: a Gynecologic Oncology Group study.
Journal: Gynecologic oncology 20111001
Title: Leflunomide with low-dose everolimus for treatment of Kaposi's sarcoma in a renal allograft recipient.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111001
Title: Sex differences in neointimal hyperplasia following endeavor zotarolimus-eluting stent implantation.
Journal: The American journal of cardiology 20111001
Title: Linking molecular feature space and disease terms for the immunosuppressive drug rapamycin.
Journal: Molecular bioSystems 20111001
Title: In vitro interaction of caspofungin and immunosuppressives against agents of mucormycosis.
Journal: The Journal of antimicrobial chemotherapy 20111001
Title: Serum levels after everolimus-stent implantation and paclitaxel-balloon angioplasty in an infant with recurrent pulmonary vein obstruction after repaired total anomalous pulmonary venous connection.
Journal: Pediatric cardiology 20111001
Title: Everolimus tablets for patients with subependymal giant cell astrocytoma.
Journal: Expert opinion on pharmacotherapy 20111001
Title: Antitumor activity of ridaforolimus and potential cell-cycle determinants of sensitivity in sarcoma and endometrial cancer models.
Journal: Molecular cancer therapeutics 20111001
Title: Inhibition of protein synthesis by TOR inactivation revealed a conserved regulatory mechanism of the BiP chaperone in Chlamydomonas.
Journal: Plant physiology 20111001
Title: De-novo calcineurin-inhibitor-free immunosuppression with sirolimus and mycophenolate mofetil after heart transplantation: 5-year results.
Journal: Current opinion in organ transplantation 20111001
Title: The TEA transcription factor Tec1 links TOR and MAPK pathways to coordinate yeast development.
Journal: Genetics 20111001
Title: Induction of autophagy with catalytic mTOR inhibitors reduces huntingtin aggregates in a neuronal cell model.
Journal: Journal of neurochemistry 20111001
Title: mTORC1 activity as a determinant of cancer risk--rationalizing the cancer-preventive effects of adiponectin, metformin, rapamycin, and low-protein vegan diets.
Journal: Medical hypotheses 20111001
Title: Role of biological targeted therapies in gastroenteropancreatic neuroendocrine tumours.
Journal: Endocrine 20111001
Title: Clinical presentation and management of mTOR inhibitor-associated stomatitis.
Journal: Oral oncology 20111001
Title: mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused.
Journal: IUBMB life 20111001
Title: Evaluation of zotarolimus-eluting metal stent in animal ureters.
Journal: Journal of endourology 20111001
Title: New target therapies for patients with neuroendocrine tumors of the pancreas.
Journal: Expert review of gastroenterology & hepatology 20111001
Title: Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activation.
Journal: Diabetes 20111001
Title: [The BASKET-PROVE study].
Journal: Giornale italiano di cardiologia (2006) 20111001
Title: Vascular response to zotarolimus-coated balloons in injured superficial femoral arteries of the familial hypercholesterolemic Swine.
Journal: Circulation. Cardiovascular interventions 20111001
Title: Rapamycin induces differentiation of glioma stem/progenitor cells by activating autophagy.
Journal: Chinese journal of cancer 20111001
Title: ERas enhances resistance to CPT-11 in gastric cancer.
Journal: Anticancer research 20111001
Title: Sunitinib re-challenge in metastatic renal cell carcinoma treated sequentially with tyrosine kinase inhibitors and everolimus.
Journal: Anticancer research 20111001
Title: Alemtuzumab preconditioning allows steroid-calcineurin inhibitor-free regimen in live-donor kidney transplant.
Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20111001
Title: A meta-analysis of specifically designed randomized trials of sirolimus-eluting versus paclitaxel-eluting stents in diabetic patients with coronary artery disease.
Journal: American heart journal 20111001
Title: [Inflammation in tumor progression].
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20111001
Title: Human peripheral blood CD8+ CD28- T cells of renal allograft recipients do not express FOXP3 protein.
Journal: Transplantation proceedings 20111001
Title: Long-term clinical and angiographic results of Sirolimus-Eluting Stent in Complex Coronary Chronic Total Occlusion Revascularization: the SECTOR registry.
Journal: Journal of interventional cardiology 20111001
Title: Erythematous patches and plaques on the chest with induration of the breasts. Metastatic papillary RCC in dermal lymphatics.
Journal: Archives of dermatology 20111001
Title: Bioresorbable polymeric vascular scaffolds: a cautionary tale.
Journal: Circulation. Cardiovascular interventions 20111001
Title: Vascular inflammation and repair: implications for re-endothelialization, restenosis, and stent thrombosis.
Journal: JACC. Cardiovascular interventions 20111001
Title: Assessing the temporal course of neointimal hyperplasia formation after different generations of drug-eluting stents.
Journal: JACC. Cardiovascular interventions 20111001
Title: Late vascular response following drug-eluting stent implantation.
Journal: JACC. Cardiovascular interventions 20111001
Title: Comparison of everolimus- and sirolimus-eluting stents in patients with long coronary artery lesions: a randomized LONG-DES-III (Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-III) Trial.
Journal: JACC. Cardiovascular interventions 20111001
Title: Comparison of everolimus- and paclitaxel-eluting stents in patients with acute and stable coronary syndromes: pooled results from the SPIRIT (A Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) and COMPARE (A Trial of Everolimus-Eluting Stents and Paclitaxel-Eluting Stents for Coronary Revascularization in Daily Practice) Trials.
Journal: JACC. Cardiovascular interventions 20111001
Title: Should everolimus-eluting stents be preferred in patients with acute and stable coronary syndromes?
Journal: JACC. Cardiovascular interventions 20111001
Title: Dual antiplatelet therapy duration and clinical outcomes following treatment with zotarolimus-eluting stents.
Journal: JACC. Cardiovascular interventions 20111001
Title: Will we ever know the optimal duration of dual antiplatelet therapy after drug-eluting stent implantation?
Journal: JACC. Cardiovascular interventions 20111001
Title: Three-dimensional reconstruction of the post-dilated ABSORB everolimus-eluting bioresorbable vascular scaffold in a true bifurcation lesion for flow restoration.
Journal: JACC. Cardiovascular interventions 20111001
Title: Two-year clinical outcomes of patients with long segments drug-eluting stents: comparison of sirolimus-eluting stent with paclitaxel-eluting stent.
Journal: Journal of Korean medical science 20111001
Title: Comparison of restenosis rate with sirolimus-eluting stent in STEMI patients with and without diabetes at 6-month angiographic follow-up.
Journal: Acta cardiologica 20111001
Title: Inactivation of mammalian target of rapamycin (mTOR) by rapamycin in a murine model of lipopolysaccharide-induced acute lung injury.
Journal: Chinese medical journal 20111001
Title: Real world clinical performance of the zotarolimus eluting coronary stent system in Chinese patients: a prospective, multicenter registry study.
Journal: Chinese medical journal 20111001
Title: Successful pregnancy complicated by persistent pneumothorax in a patient with lymphangioleiomyomatosis (LAM) on sirolimus.
Journal: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 20111001
Title: [Effects of rapamycin on cholesterol homeostasis and secretory function of 3T3-L1 cells].
Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20111001
Title: Pediatric kidney transplantation followed by de novo therapy with everolimus, low-dose cyclosporine A, and steroid elimination: 3-year data.
Journal: Transplantation 20110927
Title: RNA polymerase II degradation in response to rapamycin is not mediated through ubiquitylation.
Journal: Biochemical and biophysical research communications 20110923
Title: Switching heterotrimeric G protein subunits with a chemical dimerizer.
Journal: Chemistry & biology 20110923
Title: Biodegradable polymer versus permanent polymer drug-eluting stents and everolimus- versus sirolimus-eluting stents in patients with coronary artery disease: 3-year outcomes from a randomized clinical trial.
Journal: Journal of the American College of Cardiology 20110920
Title: Drug-eluting versus bare-metal stents in saphenous vein graft lesions (ISAR-CABG): a randomised controlled superiority trial.
Journal: Lancet (London, England) 20110917
Title: Stress-responsive sestrins link p53 with redox regulation and mammalian target of rapamycin signaling.
Journal: Antioxidants & redox signaling 20110915
Title: Rapamycin enhances the activity of oncolytic herpes simplex virus against tumor cells that are resistant to virus replication.
Journal: International journal of cancer 20110915
Title: A phase 1 study of everolimus and sorafenib for metastatic clear cell renal cell carcinoma.
Journal: Cancer 20110915
Title: Limitations in small intestinal neuroendocrine tumor therapy by mTor kinase inhibition reflect growth factor-mediated PI3K feedback loop activation via ERK1/2 and AKT.
Journal: Cancer 20110915
Title: An updated meta-analysis of randomized controlled trials of everolimus- versus paclitaxel-eluting stents.
Journal: International journal of cardiology 20110915
Title: Phase I trial of cixutumumab combined with temsirolimus in patients with advanced cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110915
Title: Using tandem mass spectrometry in targeted mode to identify activators of class IA PI3K in cancer.
Journal: Cancer research 20110915
Title: Combining EGFR and mTOR blockade for the treatment of epithelioid sarcoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110915
Title: Impact of de novo everolimus-based immunosuppression on incisional complications in heart transplantation.
Journal: Transplantation 20110915
Title: Erlotinib antagonizes constitutive activation of SRC family kinases and mTOR in acute myeloid leukemia.
Journal: Cell cycle (Georgetown, Tex.) 20110915
Title: Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors.
Journal: Cancer cell 20110913
Title: Creating diverse target-binding surfaces on FKBP12: synthesis and evaluation of a rapamycin analogue library.
Journal: ACS combinatorial science 20110912
Title: Salivary duct carcinoma: targeting the phosphatidylinositol 3-kinase pathway by blocking mammalian target of rapamycin with temsirolimus.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110910
Title: BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription.
Journal: Blood 20110908
Title: Small-molecule-based nanoassemblies as inducible nanoprobes for monitoring dynamic molecular interactions inside live cells.
Journal: Angewandte Chemie (International ed. in English) 20110905
Title: Acute cholecystitis in a patient with metastatic renal cell carcinoma treated with everolimus.
Journal: Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20110901
Title: Exaggerated inflammatory response following sirolimus-eluting stent fracture.
Journal: International journal of cardiology 20110901
Title: Rapamycin-induced posterior reversible encephalopathy in a kidney transplantation patient.
Journal: International urology and nephrology 20110901
Title: Optical coherence evaluation of everolimus-eluting stents 8 months after implantation.
Journal: Heart (British Cardiac Society) 20110901
Title: Combination of everolimus with calcineurin inhibitor medication resulted in post-transplant haemolytic uraemic syndrome in lung transplant recipients--a case series.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110901
Title: Combined inhibition of PI3K and mTOR exerts synergistic antiproliferative effect, but diminishes differentiative properties of rapamycin in acute myeloid leukemia cells.
Journal: Pathology oncology research : POR 20110901
Title: Lymphangioleiomyomatosis treatment with sirolimus.
Journal: Archivos de bronconeumologia 20110901
Title: Interaction of sirolimus and everolimus with hepatic and intestinal organic anion-transporting polypeptide transporters.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110901
Title: Toxicity spectrum of inhibitors of mammalian target of rapamycin in organ transplantation: etiology, pathogenesis and treatment.
Journal: Expert opinion on drug safety 20110901
Title: [Metastatic renal cell cancer in Germany in 2010. Impact of different target therapies].
Journal: Der Urologe. Ausg. A 20110901
Title: Sirolimus demonstrates activity in the primary therapy of acute graft-versus-host disease without systemic glucocorticoids.
Journal: Haematologica 20110901
Title: Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells.
Journal: Haematologica 20110901
Title: Intracellular angiotensin II activates rat myometrium.
Journal: American journal of physiology. Cell physiology 20110901
Title: Sirolimus-eluting stents vs. bare-metal stents for treatment of focal lesions in infrapopliteal arteries: a double-blind, multi-centre, randomized clinical trial.
Journal: European heart journal 20110901
Title: Assessment of the safety and biodistribution of a regulated AAV2 gene transfer vector after delivery to murine submandibular glands.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110901
Title: New therapeutic options for metastatic malignant insulinomas.
Journal: Clinical endocrinology 20110901
Title: A combined approach of classical mutagenesis and rational metabolic engineering improves rapamycin biosynthesis and provides insights into methylmalonyl-CoA precursor supply pathway in Streptomyces hygroscopicus ATCC 29253.
Journal: Applied microbiology and biotechnology 20110901
Title: Paronychia and pyogenic granuloma induced by new anticancer mTOR inhibitors.
Journal: Acta dermato-venereologica 20110901
Title: Mesenchymal stem cells and carcinoma-associated fibroblasts sensitize breast cancer cells in 3D cultures to kinase inhibitors.
Journal: International journal of oncology 20110901
Title: Comparison of drug-eluting versus bare metal stents in cardiac allograft vasculopathy.
Journal: The American journal of cardiology 20110901
Title: Telmisartan reduces neointima volume and pulse wave velocity 8 months after zotarolimus-eluting stent implantation in hypertensive type 2 diabetic patients.
Journal: Heart (British Cardiac Society) 20110901
Title: The mTOR protein as a target in thyroid cancer.
Journal: Expert opinion on therapeutic targets 20110901
Title: Features of synergism between mesenchymal stem cells and immunosuppressive drugs in a murine heart transplantation model.
Journal: Transplant immunology 20110901
Title: Cystogenic potential of CD133+ progenitor cells of human polycystic kidneys.
Journal: The Journal of pathology 20110901
Title: Percutaneous coronary intervention in Takayasu's arteritis.
Journal: International journal of cardiology 20110901
Title: Influence of immunosuppressive agents on tryptophan degradation and neopterin production in human peripheral blood mononuclear cells.
Journal: Transplant immunology 20110901
Title: Role of the AMPK/SREBP-1 pathway in the development of orotic acid-induced fatty liver.
Journal: Journal of lipid research 20110901
Title: Current management of lymphangioleiomyomatosis.
Journal: Current opinion in pulmonary medicine 20110901
Title: Sirolimus and growth.
Journal: Pediatric transplantation 20110901
Title: Identification of novel rapamycin derivatives as low-level impurities in active pharmaceutical ingredients.
Journal: The Journal of antibiotics 20110901
Title: Influence of low-dose aspirin (81 mg) on the incidence of definite stent thrombosis in patients receiving bare-metal and drug-eluting stents.
Journal: Clinical cardiology 20110901
Title: Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection.
Journal: The Journal of clinical investigation 20110901
Title: Randomized trial of immunosuppressive regimens in renal transplantation.
Journal: Journal of the American Society of Nephrology : JASN 20110901
Title: Managing refractory metastatic renal cell carcinoma: a RECORD spinning on a tilted AXIS.
Journal: Clinical genitourinary cancer 20110901
Title: Effects of immunosuppressive therapy after experimental small bowel transplantation in rats.
Journal: Transplant immunology 20110901
Title: Phase I trial of lenalidomide and CCI-779 in patients with relapsed multiple myeloma: evidence for lenalidomide-CCI-779 interaction via P-glycoprotein.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110901
Title: Editorial.
Journal: Current opinion in pulmonary medicine 20110901
Title: Sirolimus for acute pemphigus vulgaris: a case report and discussion of dualistic action providing for both immunosuppression and keratinocyte protection.
Journal: Journal of the American Academy of Dermatology 20110901
Title: Neuroendocrine regulation of autophagy by leptin.
Journal: Cell cycle (Georgetown, Tex.) 20110901
Title: The mTOR inhibitor RAD001 sensitizes tumor cells to the cytotoxic effect of carboplatin in breast cancer in vitro.
Journal: Anticancer research 20110901
Title: Involvement of Akt and mTOR in chemotherapeutic- and hormonal-based drug resistance and response to radiation in breast cancer cells.
Journal: Cell cycle (Georgetown, Tex.) 20110901
Title: Sirolimus-based immunosuppression for treatment of cutaneous warts in kidney transplant recipients.
Journal: Iranian journal of kidney diseases 20110901
Title: Graft-versus-host disease therapy: something else beyond glucocorticoids?
Journal: Haematologica 20110901
Title: Renal carcinoma with (6;11)(p21;q12) translocation: report of an adult case.
Journal: Pathology international 20110901
Title: Linear growth in pediatric renal transplant recipients receiving sirolimus.
Journal: Pediatric transplantation 20110901
Title: Persistent dyspnea in a 59-year-old woman receiving immunosuppressants.
Journal: Chest 20110901
Title: Long-term experience with everolimus in kidney transplantation in the United States.
Journal: Transplantation proceedings 20110901
Title: A retrospective 12-month study of conversion to everolimus in lung transplant recipients.
Journal: Transplantation proceedings 20110901
Title: Sirolimus-induced pneumonitis complicated by pentamidine-induced phospholipidosis in a renal transplant recipient: a case report.
Journal: Transplantation proceedings 20110901
Title: Everolimus and sunitinib: from mouse models to treatment of pancreatic neuroendocrine tumors.
Journal: Future oncology (London, England) 20110901
Title: IVUS and OCT: either or survivor ….
Journal: JACC. Cardiovascular imaging 20110901
Title: Hepatocellular carcinoma and liver transplantation: clinical perspective on molecular targeted strategies.
Journal: Medical molecular morphology 20110901
Title: Three-year outcome of sirolimus-eluting stent implantation in coronary bifurcation lesions: the provisional side branch stenting approach versus the elective two-stent approach.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110901
Title: Implantation of the biodegradable polymer biolimus-eluting stent in patients with high SYNTAX score is associated with decreased cardiac mortality compared to a permanent polymer sirolimus-eluting stent: two year follow-up results from the 'all-comers' LEADERS trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110901
Title: Bifurcation Optimisation Stent System (BiOSS Lim) with sirolimus elution: results from porcine coronary artery model.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110901
Title: Dramatic improvement of facial angiofibromas in tuberous sclerosis with topical rapamycin: optimizing a treatment protocol.
Journal: Archives of dermatology 20110901
Title: Impact of intravascular ultrasound imaging on early and late clinical outcomes following percutaneous coronary intervention with drug-eluting stents.
Journal: JACC. Cardiovascular interventions 20110901
Title: Sirolimus-eluting coronary stents in octogenarians: a 1-year analysis of the worldwide e-SELECT Registry.
Journal: JACC. Cardiovascular interventions 20110901
Title: Serial analysis of the malapposed and uncovered struts of the new generation of everolimus-eluting bioresorbable scaffold with optical coherence tomography.
Journal: JACC. Cardiovascular interventions 20110901
Title: Total aorto-ostial chronic occlusion of the right coronary artery successfully recanalized via retrograde approach.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110901
Title: [Synergistic cytotoxic effects of rapamycin and idarubicin on human acute T-cell lymphoblastic leukemia Jurkat cells].
Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110901
Title: The successful management of diffuse lymphangiomatosis using sirolimus: a case report.
Journal: The Laryngoscope 20110901
Title: [Ryanodine downregulates the expression of p-eNOS (Thr495) and improves the functions of rapamycin treated endothelial outgrowth cells].
Journal: Zhonghua xin xue guan bing za zhi 20110901
Title: [Basic efficiently of drug eluting stent 2011].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20110901
Title: [Sirolimis-eluting stent (SES)].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20110901
Title: [Zotarolimus-eluting stent].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20110901
Title: [Everolimus-eluting stent].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20110901
Title: [Biolimus eluting stent].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20110901
Title: [Effect of RAD001 or plus LBH589 on the proliferation, apoptosis and drug resistance in chemoresistant acute myeloid leukemic cells].
Journal: Zhonghua yi xue za zhi 20110830
Title: Conversion of long-term kidney transplant recipients from calcineurin inhibitor therapy to everolimus: a randomized, multicenter, 24-month study.
Journal: Transplantation 20110827
Title: Role of S6K1 in regulation of SREBP1c expression in the liver.
Journal: Biochemical and biophysical research communications 20110826
Title: Localized ultrasound enhances delivery of rapamycin from microbubbles to prevent smooth muscle proliferation.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20110825
Title: Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1/2 study in patients with myelofibrosis.
Journal: Blood 20110825
Title: Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4+CD25+Foxp3+ regulatory T cells.
Journal: Blood 20110825
Title: Randomized comparison of everolimus-eluting stent versus sirolimus-eluting stent implantation for de novo coronary artery disease in patients with diabetes mellitus (ESSENCE-DIABETES): results from the ESSENCE-DIABETES trial.
Journal: Circulation 20110823
Title: Differential clinical responses to everolimus-eluting and Paclitaxel-eluting coronary stents in patients with and without diabetes mellitus.
Journal: Circulation 20110823
Title: Is diabetes the achilles' heel of limus-eluting stents?
Journal: Circulation 20110823
Title: Phase II study of temsirolimus in women with recurrent or metastatic endometrial cancer: a trial of the NCIC Clinical Trials Group.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110820
Title: Sirolimus- vs. paclitaxel-eluting stents for the treatment of unprotected left main coronary artery stenosis: complete 2-year follow-up of a two-center registry.
Journal: International journal of cardiology 20110818
Title: Regulation of TFEB and V-ATPases by mTORC1.
Journal: The EMBO journal 20110817
Title: Inhibition of mammalian target of rapamycin signaling by everolimus induces senescence in adult T-cell leukemia/lymphoma and apoptosis in peripheral T-cell lymphomas.
Journal: International journal of cancer 20110815
Title: Everolimus-eluting versus paclitaxel-eluting stents for treatment of bare metal stent restenosis.
Journal: The American journal of cardiology 20110815
Title: Therapeutic efficacy of polyclonal tregs does not require rapamycin in a low-dose irradiation bone marrow transplantation model.
Journal: Transplantation 20110815
Title: Lower malignancy rates in renal allograft recipients converted to sirolimus-based, calcineurin inhibitor-free immunotherapy: 24-month results from the CONVERT trial.
Journal: Transplantation 20110815
Title: Antagonistic control of muscle cell size by AMPK and mTORC1.
Journal: Cell cycle (Georgetown, Tex.) 20110815
Title: Everolimus and long-term outcomes in renal transplantation: seeking an optimal strategy for immunosuppression.
Journal: Transplantation 20110815
Title: Everolimus and long-term outcomes in renal transplantation.
Journal: Transplantation 20110815
Title: Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110810
Title: Polymer-free sirolimus- and probucol-eluting versus new generation zotarolimus-eluting stents in coronary artery disease: the Intracoronary Stenting and Angiographic Results: Test Efficacy of Sirolimus- and Probucol-Eluting versus Zotarolimus-eluting Stents (ISAR-TEST 5) trial.
Journal: Circulation 20110802
Title: Human herpes virus type 8-associated Kaposi sarcoma in a pediatric liver transplant recipient.
Journal: Pediatric transplantation 20110801
Title: The mammalian target of rapamycin inhibitor everolimus (RAD001) in early breast cancer: results of a pre-operative study.
Journal: Breast cancer research and treatment 20110801
Title: Are we missing the mTOR target in breast cancer?
Journal: Breast cancer research and treatment 20110801
Title: Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis.
Journal: Journal of hepatology 20110801
Title: A phase 2 study of temsirolimus (CCI-779) in patients with soft tissue sarcomas: a study of the Mayo phase 2 consortium (P2C).
Journal: Cancer 20110801
Title: The management of subependymal giant cell tumors in tuberous sclerosis: a clinician's perspective.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20110801
Title: Oral rapamycin in the treatment of patients with hamartoma syndromes and PTEN mutation.
Journal: Pediatric blood & cancer 20110801
Title: Conversion to everolimus in maintenance liver transplant patients: a multicenter, retrospective analysis.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20110801
Title: Angiographic outcomes with biodegradable polymer and permanent polymer drug-eluting stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110801
Title: The influence of co-solvents on the stability and bioavailability of rapamycin formulated in self-microemulsifying drug delivery systems.
Journal: Drug development and industrial pharmacy 20110801
Title: Low stent thrombosis risk with the XIENCE V® Everolimus-Eluting Coronary Stent: evidence from randomized and single-arm clinical trials.
Journal: Journal of interventional cardiology 20110801
Title: Cannabinoid receptor agonists modulate oligodendrocyte differentiation by activating PI3K/Akt and the mammalian target of rapamycin (mTOR) pathways.
Journal: British journal of pharmacology 20110801
Title: FKBPs in chromatin modification and cancer.
Journal: Current opinion in pharmacology 20110801
Title: Successful treatment of systemic de novo sarcoidosis with cyclosporine discontinuation and provision of rapamune after liver transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20110801
Title: A pulse rapamycin therapy for infantile spasms and associated cognitive decline.
Journal: Neurobiology of disease 20110801
Title: Hepatocyte growth factor-induced c-Src-phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway inhibits dendritic cell activation by blocking IκB kinase activity.
Journal: The international journal of biochemistry & cell biology 20110801
Title: Subsets of human CD4(+) regulatory T cells express the peripheral homing receptor CXCR3.
Journal: European journal of immunology 20110801
Title: Focus.
Journal: Journal of hepatology 20110801
Title: Induction of tolerance to factor VIII by transient co-administration with rapamycin.
Journal: Journal of thrombosis and haemostasis : JTH 20110801
Title: Sustained targeting of Bcr-Abl + leukemia cells by synergistic action of dual drug loaded nanoparticles and its implication for leukemia therapy.
Journal: Biomaterials 20110801
Title: Inhibition of the mTOR/p70S6K pathway is not involved in the insulin-sensitizing effect of AMPK on cardiac glucose uptake.
Journal: American journal of physiology. Heart and circulatory physiology 20110801
Title: A 3-in-1 polymeric micelle nanocontainer for poorly water-soluble drugs.
Journal: Molecular pharmaceutics 20110801
Title: Modulation of morphogenesis in Candida albicans by various small molecules.
Journal: Eukaryotic cell 20110801
Title: Cholesterol esters as growth regulators of lymphocytic leukaemia cells.
Journal: Cell proliferation 20110801
Title: Tilt balance towards regulation: evolving new strategy for treatment of hemophilia inhibitors.
Journal: Journal of thrombosis and haemostasis : JTH 20110801
Title: First clinical trial of nitinol self-expanding everolimus-eluting stent implantation for peripheral arterial occlusive disease.
Journal: Journal of vascular surgery 20110801
Title: The ORION study: comparison of two sirolimus-based regimens versus tacrolimus and mycophenolate mofetil in renal allograft recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110801
Title: How to use mTOR inhibitors? The search goes on.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110801
Title: Rapamycin-induced hypophosphatemia and insulin resistance are associated with mTORC2 activation and Klotho expression.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110801
Title: Preclinical characterization of OSI-027, a potent and selective inhibitor of mTORC1 and mTORC2: distinct from rapamycin.
Journal: Molecular cancer therapeutics 20110801
Title: Direct activation of mTOR in B lymphocytes confers impairment in B-cell maturation andloss of marginal zone B cells.
Journal: European journal of immunology 20110801
Title: Combinatorial effects of lapatinib and rapamycin in triple-negative breast cancer cells.
Journal: Molecular cancer therapeutics 20110801
Title: The use of everolimus in pediatric liver transplant recipients: first experience in a single center.
Journal: Pediatric transplantation 20110801
Title: Sirolimus-eluting stent implantation for ostial left anterior descending coronary artery lesions: three-year outcome from the j-Cypher Registry.
Journal: Circulation. Cardiovascular interventions 20110801
Title: The mTOR/AKT inhibitor temsirolimus prevents deep infiltrating endometriosis in mice.
Journal: The American journal of pathology 20110801
Title: Evaluation of the Abbott ARCHITECT i2000 sirolimus assay and comparison with the Abbott IMx sirolimus assay and an established liquid chromatography-tandem mass spectrometry method.
Journal: Therapeutic drug monitoring 20110801
Title: Evaluation of performance of new, isotopically labeled internal standard ([13c2d4]RAD001) for everolimus using a novel high-performance liquid chromatography tandem mass spectrometry method.
Journal: Therapeutic drug monitoring 20110801
Title: TORCing up the importance of calcium signaling.
Journal: Journal of the American Society of Nephrology : JASN 20110801
Title: Skin cancer in solid organ transplant recipients: advances in therapy and management: part I. Epidemiology of skin cancer in solid organ transplant recipients.
Journal: Journal of the American Academy of Dermatology 20110801
Title: mTor plays an important role in odontoblast differentiation.
Journal: Journal of endodontics 20110801
Title: mTOR inhibitors in advanced renal cell carcinoma.
Journal: Hematology/oncology clinics of North America 20110801
Title: Quality of life and targeted treatment for metastatic renal cell carcinoma.
Journal: The oncologist 20110801
Title: How can we miss you, if you will never leave? Biodegradable stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110801
Title: Everolimus-eluting versus sirolimus-eluting stents: a meta-analysis of randomized trials.
Journal: Circulation. Cardiovascular interventions 20110801
Title: A phase II trial of bevacizumab plus everolimus for patients with refractory metastatic colorectal cancer.
Journal: The oncologist 20110801
Title: Efficacy and safety of early cyclosporine conversion to sirolimus with continued MMF-four-year results of the Postconcept study.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110801
Title: Impact of sirolimus-eluting stent fracture on 4-year clinical outcomes.
Journal: Circulation. Cardiovascular interventions 20110801
Title: Everolimus vs. rapamycin for treating diabetic nephropathy in diabetic mouse model.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20110801
Title: Effects of rapamycin on expression of Bcl-2 and Bax in human lens epithelial cells and cell cycle in rats.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20110801
Title: Comparison of six-year clinical outcome of sirolimus- and paclitaxel-eluting stents to bare-metal stents in patients with ST-segment elevation myocardial infarction: an analysis of the RESEARCH (rapamycin-eluting stent evaluated at Rotterdam cardiology hospital) and T-SEARCH (taxus stent evaluated at Rotterdam cardiology hospital) registries.
Journal: The Journal of invasive cardiology 20110801
Title: Long-term benefit using DES in STEMI patients.
Journal: The Journal of invasive cardiology 20110801
Title: Rapamycin as an antiaging therapeutic?: targeting mammalian target of rapamycin to treat Hutchinson-Gilford progeria and neurodegenerative diseases.
Journal: Rejuvenation research 20110801
Title: Meeting report: American Aging Association 40th Annual Meeting, Raleigh, North Carolina, June 3-6, 2011.
Journal: Rejuvenation research 20110801
Title: 2-year clinical follow-up from the randomized comparison of biolimus-eluting stents with biodegradable polymer and sirolimus-eluting stents with durable polymer in routine clinical practice.
Journal: JACC. Cardiovascular interventions 20110801
Title: Everolimus: an mTOR inhibitor for the treatment of tuberous sclerosis.
Journal: Expert review of anticancer therapy 20110801
Title: [Rapamycin for myeloid blast crisis in refractory chronic myeloid leukemia with imatinib-resistance].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110801
Title: A shining light in the darkness for the treatment of pancreatic neuroendocrine tumors.
Journal: Cancer discovery 20110801
Title: Use of remote film loading methodology to entrap sirolimus into liposomes: preparation, characterization and in vivo efficacy for treatment of restenosis.
Journal: International journal of pharmaceutics 20110729
Title: Controlled poly(l-lactide-co-trimethylene carbonate) delivery system of cyclosporine A and rapamycine--the effect of copolymer chain microstructure on drug release rate.
Journal: International journal of pharmaceutics 20110729
Title: Everolimus for cardiac allograft vasculopathy--every patient, at any time?
Journal: Transplantation 20110727
Title: Racial variation in the development of posttransplant lymphoproliferative disorders after renal transplantation.
Journal: Transplantation 20110727
Title: Effect of everolimus introduction on cardiac allograft vasculopathy--results of a randomized, multicenter trial.
Journal: Transplantation 20110727
Title: [Adverse effects of new oncologic therapies].
Journal: Praxis 20110727
Title: PIK3CA mutation, but not PTEN loss of function, determines the sensitivity of breast cancer cells to mTOR inhibitory drugs.
Journal: Oncogene 20110721
Title: Efficacy and safety of sirolimus in lymphangioleiomyomatosis.
Journal: The New England journal of medicine 20110721
Title: Efficacy and safety of sirolimus in lymphangioleiomyomatosis.
Journal: The New England journal of medicine 20110721
Title: Phase I study of temsirolimus in pediatric patients with recurrent/refractory solid tumors.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110720
Title: Fighting neurodegeneration with rapamycin: mechanistic insights.
Journal: Nature reviews. Neuroscience 20110720
Title: The role of autophagy emerging in postinfarction cardiac remodelling.
Journal: Cardiovascular research 20110715
Title: Transplant-associated thrombotic microangiopathy in pediatric patients treated with sirolimus and tacrolimus.
Journal: Pediatric blood & cancer 20110715
Title: Effect of pioglitazone on endothelial dysfunction after sirolimus-eluting stent implantation.
Journal: The American journal of cardiology 20110715
Title: mTORC2 protein complex-mediated Akt (Protein Kinase B) Serine 473 Phosphorylation is not required for Akt1 activity in human platelets [corrected].
Journal: The Journal of biological chemistry 20110715
Title: CCI-779 inhibits cell-cycle G2-M progression and invasion of castration-resistant prostate cancer via attenuation of UBE2C transcription and mRNA stability.
Journal: Cancer research 20110715
Title: Inhibiting the mTOR pathway synergistically enhances cytotoxicity in ovarian cancer cells induced by etoposide through upregulation of c-Jun.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110715
Title: Insights into ALK-driven cancers revealed through development of novel ALK tyrosine kinase inhibitors.
Journal: Cancer research 20110715
Title: Everolimus- versus first generation drug-eluting stents: the never-ending story of searching for a winner in the 'limus family'.
Journal: International journal of cardiology 20110715
Title: The power of chemotherapeutic engineering: arresting cell cycle and suppressing senescence to protect from mitotic inhibitors.
Journal: Cell cycle (Georgetown, Tex.) 20110715
Title: Stents versus CABG for left main coronary artery disease.
Journal: The New England journal of medicine 20110714
Title: Stents versus CABG for left main coronary artery disease.
Journal: The New England journal of medicine 20110714
Title: 6-month clinical outcomes following implantation of the bioresorbable everolimus-eluting vascular scaffold in vessels smaller or larger than 2.5 mm.
Journal: Journal of the American College of Cardiology 20110712
Title: L-threonine regulates G1/S phase transition of mouse embryonic stem cells via PI3K/Akt, MAPKs, and mTORC pathways.
Journal: The Journal of biological chemistry 20110708
Title: Rapamycin (sirolimus) protects against hypoxic damage in primary heart cultures via Na+/Ca2+ exchanger activation.
Journal: Life sciences 20110704
Title: Comparison of chronic-stage histopathological findings among 3 coronary stents implanted in the same patient.
Journal: International journal of cardiology 20110701
Title: Rapamycin synergizes cisplatin sensitivity in basal-like breast cancer cells through up-regulation of p73.
Journal: Breast cancer research and treatment 20110701
Title: Temporal changes of coronary artery plaque located behind the struts of the everolimus eluting bioresorbable vascular scaffold.
Journal: The international journal of cardiovascular imaging 20110701
Title: Down-regulation of the ubiquitin-proteasome proteolysis system by amino acids and insulin involves the adenosine monophosphate-activated protein kinase and mammalian target of rapamycin pathways in rat hepatocytes.
Journal: Amino acids 20110701
Title: Long-term (≥2 years) follow-up optical coherence tomographic study after sirolimus- and paclitaxel-eluting stent implantation: comparison to 9-month follow-up results.
Journal: The international journal of cardiovascular imaging 20110701
Title: The mTOR pathway affects proliferation and chemosensitivity of urothelial carcinoma cells and is upregulated in a subset of human bladder cancers.
Journal: BJU international 20110701
Title: mTORC1 activation in childhood ependymoma and response to sirolimus.
Journal: Journal of neuro-oncology 20110701
Title: Serial angiographic and intravascular ultrasound evaluation to interrogate the presence of late 'catch-up' phenomenon after Cypher® sirolimus-eluting stent implantation.
Journal: The international journal of cardiovascular imaging 20110701
Title: Long-term outcome after sirolimus-eluting stents versus bare metal stents in patients with diabetes mellitus: a patient-level meta-analysis of randomized trials.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20110701
Title: Twelve-month clinical outcomes of everolimus-eluting stent as compared to paclitaxel- and sirolimus-eluting stent in patients undergoing percutaneous coronary interventions. A meta-analysis of randomized clinical trials.
Journal: International journal of cardiology 20110701
Title: Percutaneous intervention of a thrombotic-occluded saphenous vein graft successfully treated using the undersized stent approach to prevent distal embolization.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110701
Title: An investigator-driven study of everolimus in surgical lung biopsy confirmed idiopathic pulmonary fibrosis.
Journal: Respirology (Carlton, Vic.) 20110701
Title: Comparison of in vivo acute stent recoil between the bioresorbable everolimus-eluting coronary scaffolds (revision 1.0 and 1.1) and the metallic everolimus-eluting stent.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110701
Title: Dual mTORC2/mTORC1 targeting results in potent suppressive effects on acute myeloid leukemia (AML) progenitors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110701
Title: Primum non nocere: safety in clinical trials for IPF.
Journal: Respirology (Carlton, Vic.) 20110701
Title: A phase I study of sirolimus and bevacizumab in patients with advanced malignancies.
Journal: European journal of cancer (Oxford, England : 1990) 20110701
Title: Curcumin disrupts uterine leiomyosarcoma cells through AKT-mTOR pathway inhibition.
Journal: Gynecologic oncology 20110701
Title: Rapamycin inhibits formation of urethral stricture in rabbits.
Journal: The Journal of pharmacology and experimental therapeutics 20110701
Title: The serine/threonine kinase Pim-2 is a novel anti-apoptotic mediator in myeloma cells.
Journal: Leukemia 20110701
Title: Rapamycin-sensitive signals control TCR/CD28-driven Ifng, Il4 and Foxp3 transcription and promoter region methylation.
Journal: European journal of immunology 20110701
Title: Responses to liposomal Doxorubicin, bevacizumab, and temsirolimus in metaplastic carcinoma of the breast: biologic rationale and implications for stem-cell research in breast cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110701
Title: Relapse of aplastic anemia responsive to sirolimus combined with cyclosporine.
Journal: Pediatric blood & cancer 20110701
Title: Meta-analysis of everolimus-eluting stent as compared to sirolimus-eluting stent in patients undergoing percutaneous coronary interventions: an update.
Journal: International journal of cardiology 20110701
Title: Starvation and rapamycin differentially regulate host cell lysosome exocytosis and invasion by Trypanosoma cruzi metacyclic forms.
Journal: Cellular microbiology 20110701
Title: mTORC1 inhibition increases neurotensin secretion and gene expression through activation of the MEK/ERK/c-Jun pathway in the human endocrine cell line BON.
Journal: American journal of physiology. Cell physiology 20110701
Title: Inhibition of mTOR by temsirolimus contributes to prolonged survival of mice with pleural dissemination of non-small-cell lung cancer cells.
Journal: Cancer science 20110701
Title: Phase I trial of capecitabine plus everolimus (RAD001) in patients with previously treated metastatic gastric cancer.
Journal: Cancer chemotherapy and pharmacology 20110701
Title: CD4(+)CD25(high)CD127(low) regulatory T cells in patients with stable angina and their dynamics after intracoronary sirolimus-eluting stent implantation.
Journal: Human immunology 20110701
Title: Continuing response to subsequent treatment lines with tyrosine kinase inhibitors in an adolescent with metastatic renal cell carcinoma.
Journal: Journal of pediatric hematology/oncology 20110701
Title: Rheb/mTOR activation and regulation in cancer: novel treatment strategies beyond rapamycin.
Journal: Current drug targets 20110701
Title: Role of ROS in the protective effect of silibinin on sodium nitroprusside-induced apoptosis in rat pheochromocytoma PC12 cells.
Journal: Free radical research 20110701
Title: High-throughput LC-MS/MS method for monitoring sirolimus and everolimus in the routine clinical laboratory.
Journal: Clinical chemistry and laboratory medicine 20110701
Title: Rapamycin partially mimics the anticancer effects of calorie restriction in a murine model of pancreatic cancer.
Journal: Cancer prevention research (Philadelphia, Pa.) 20110701
Title: Rapamycin-conditioned, alloantigen-pulsed myeloid dendritic cells present donor MHC class I/peptide via the semi-direct pathway and inhibit survival of antigen-specific CD8(+) T cells in vitro and in vivo.
Journal: Transplant immunology 20110701
Title: An adjusted indirect comparison of everolimus and sorafenib therapy in sunitinib-refractory metastatic renal cell carcinoma patients using repeated matched samples.
Journal: Expert opinion on pharmacotherapy 20110701
Title: Involvement of 4E-BP phosphorylation in embryonic development of the silkworm, Bombyx mori.
Journal: Journal of insect physiology 20110701
Title: Combination of PI3K/mTOR inhibitors: antitumor activity and molecular correlates.
Journal: Cancer research 20110701
Title: Restenosis after implantation of sirolimus-eluting stent begins suddenly, shows short term progression, and stops suddenly.
Journal: Journal of cardiology 20110701
Title: The activity of trabectedin as a single agent or in combination with everolimus for clear cell carcinoma of the ovary.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110701
Title: S6 kinase 1 is required for rapamycin-sensitive liver proliferation after mouse hepatectomy.
Journal: The Journal of clinical investigation 20110701
Title: mTOR and the differentiation of mesenchymal stem cells.
Journal: Acta biochimica et biophysica Sinica 20110701
Title: Temsirolimus and bevacizumab, or sunitinib, or interferon alfa and bevacizumab for patients with advanced renal cell carcinoma (TORAVA): a randomised phase 2 trial.
Journal: The Lancet. Oncology 20110701
Title: Combination therapy in metastatic renal cell carcinoma.
Journal: The Lancet. Oncology 20110701
Title: Structural identification of SAR-943 metabolites generated by human liver microsomes in vitro using mass spectrometry in combination with analysis of fragmentation patterns.
Journal: Journal of mass spectrometry : JMS 20110701
Title: Modulation of autophagy influences development and apoptosis in mouse embryos developing in vitro.
Journal: Molecular reproduction and development 20110701
Title: Testing the strength of biodegradable stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110701
Title: Cost-effectiveness of drug-eluting stents versus bare metal stents in clinical practice.
Journal: Circulation. Cardiovascular quality and outcomes 20110701
Title: [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma].
Journal: Aktuelle Urologie 20110701
Title: [The influence of rapamycin on BTLA expression of human peripheral blood T lymphocytes].
Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20110701
Title: Monitoring ketamine treatment response in a depressed patient via peripheral mammalian target of rapamycin activation.
Journal: The American journal of psychiatry 20110701
Title: Successful stent implantation guided by intravascular ultrasound and a Doppler guidewire without contrast injection in a patient with allergy to iodinated contrast media.
Journal: The Journal of invasive cardiology 20110701
Title: Transient coronary aneurysm formation after Nevo™ stent implantation versus persistent coronary aneurysm after Cypher Select™ stent implantation.
Journal: The Journal of invasive cardiology 20110701
Title: Local delivery of rapamycin: a toxicity and efficacy study in an experimental malignant glioma model in rats.
Journal: Neuro-oncology 20110701
Title: Should stent selection in diabetic patients be considered as a special case?
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110701
Title: Clinical and angiographic outcomes of elderly patients treated with everolimus-eluting versus paclitaxel-eluting stents: three-year results from the SPIRIT III randomised trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110701
Title: Late lumen loss and intima hyperplasia after sirolimus-eluting and zotarolimus-eluting stent implantation in diabetic patients: the diabetes and drug-eluting stent (DiabeDES III) angiography and intravascular ultrasound trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110701
Title: Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy.
Journal: Oncotarget 20110701
Title: Ridaforolimus: a promising drug in the treatment of soft-tissue sarcoma and other malignancies.
Journal: Future oncology (London, England) 20110701
Title: Rapamycin is a potent inhibitor of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Journal: Cancer prevention research (Philadelphia, Pa.) 20110701
Title: Changes in reference vessel diameter in ST-segment elevation myocardial infarction after primary percutaneous coronary intervention: implications for appropriate stent sizing.
Journal: American heart journal 20110701
Title: Progeria, rapamycin and normal aging: recent breakthrough.
Journal: Aging 20110701
Title: Impact of drug release kinetics on vascular response to different zotarolimus-eluting stents implanted in patients with long coronary stenoses: the LongOCT study (Optical Coherence Tomography in Long Lesions).
Journal: JACC. Cardiovascular interventions 20110701
Title: Linking drug-eluting stent kinetics and clinical outcomes: insights from optical coherence tomography.
Journal: JACC. Cardiovascular interventions 20110701
Title: Development of a biodegradable sirolimus-eluting stent coated by ultrasonic atomizing spray.
Journal: Journal of nanoscience and nanotechnology 20110701
Title: An increase in basal BDNF provokes hyperactivation of the Akt-mammalian target of rapamycin pathway and deregulation of local dendritic translation in a mouse model of Down's syndrome.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110629
Title: Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells.
Journal: Science translational medicine 20110629
Title: 2-year follow-up of a randomized controlled trial of everolimus- and paclitaxel-eluting stents for coronary revascularization in daily practice. COMPARE (Comparison of the everolimus eluting XIENCE-V stent with the paclitaxel eluting TAXUS LIBERTÉ stent in all-comers: a randomized open label trial).
Journal: Journal of the American College of Cardiology 20110628
Title: Randomized comparison of everolimus- and paclitaxel-eluting stents. 2-year follow-up from the SPIRIT (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) IV trial.
Journal: Journal of the American College of Cardiology 20110628
Title: Second-generation drug-eluting stents. Moving the field forward.
Journal: Journal of the American College of Cardiology 20110628
Title: Tacrolimus and sirolimus induce reproductive abnormalities in female rats.
Journal: Transplantation 20110627
Title: Five-year outcomes of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: are they equally good (or bad)?
Journal: Circulation 20110621
Title: Five-year clinical and angiographic outcomes of a randomized comparison of sirolimus-eluting and paclitaxel-eluting stents: results of the Sirolimus-Eluting Versus Paclitaxel-Eluting Stents for Coronary Revascularization LATE trial.
Journal: Circulation 20110621
Title: Summaries for patients. Sirolimus therapy in patients with lymphangioleiomyomatosis.
Journal: Annals of internal medicine 20110621
Title: Changes in lung function and chylous effusions in patients with lymphangioleiomyomatosis treated with sirolimus.
Journal: Annals of internal medicine 20110621
Title: Tuberous sclerosis complex and lymphangioleiomyomatosis: miles to go, promises to keep.
Journal: Annals of internal medicine 20110621
Title: Mammalian target of rapamycin: a central node of complex signaling cascades.
Journal: International journal of clinical and experimental pathology 20110620
Title: A proof of concept phase II non-inferiority criterion.
Journal: Statistics in medicine 20110615
Title: Outcomes after unrestricted use of everolimus-eluting stent compared to paclitaxel- and sirolimus-eluting stents.
Journal: The American journal of cardiology 20110615
Title: Sirolimus therapy for angiomyolipoma in tuberous sclerosis and sporadic lymphangioleiomyomatosis: a phase 2 trial.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110615
Title: Comparison of everolimus-eluting stent with paclitaxel-eluting stent in long chronic total occlusions.
Journal: The American journal of cardiology 20110615
Title: mTOR kinase inhibitor AZD8055 enhances the immunotherapeutic activity of an agonist CD40 antibody in cancer treatment.
Journal: Cancer research 20110615
Title: Persistent long-term synaptic plasticity requires activation of a new signaling pathway by additional stimuli.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110615
Title: Intestinal absorption and intestinal lymphatic transport of sirolimus from self-microemulsifying drug delivery systems assessed using the single-pass intestinal perfusion (SPIP) technique and a chylomicron flow blocking approach: linear correlation with oral bioavailabilities in rats.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110614
Title: [Role of rapamycin in cholangiocytes regeneration after liver transplantation].
Journal: Zhonghua yi xue za zhi 20110614
Title: Cell signaling. New mTOR targets Grb attention.
Journal: Science (New York, N.Y.) 20110610
Title: The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.
Journal: Science (New York, N.Y.) 20110610
Title: Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling.
Journal: Science (New York, N.Y.) 20110610
Title: Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling.
Journal: Cell metabolism 20110608
Title: Late asymptomatic sirolimus-eluting stent fracture in a female with systemic lupus erythematosus.
Journal: International journal of cardiology 20110602
Title: Leucine promotes leptin receptor expression in mouse C2C12 myotubes through the mTOR pathway.
Journal: Molecular biology reports 20110601
Title: Thrombotic thrombocytopenic purpura associated with everolimus use in a renal transplant patient.
Journal: International urology and nephrology 20110601
Title: The selective VEGFR1-3 inhibitor axitinib (AG-013736) shows antitumor activity in human neuroblastoma xenografts.
Journal: International journal of cancer 20110601
Title: Retinoic acid induces autophagosome maturation through redistribution of the cation-independent mannose-6-phosphate receptor.
Journal: Antioxidants & redox signaling 20110601
Title: Four-year clinical follow-up of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with de novo coronary artery lesions: the SPIRIT II trial.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110601
Title: Extended follow-up safety and effectiveness of the Endeavor zotarolimus-eluting stent in real-world clinical practice: two-year follow-up from the E-Five Registry.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110601
Title: Prophylaxis with sirolimus and tacrolimus ± antithymocyte globulin reduces the risk of acute graft-versus-host disease without an overall survival benefit following allogeneic stem cell transplantation.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110601
Title: Donor pre-treatment with everolimus or cyclosporine does not reduce ischaemia-reperfusion injury in a rat kidney transplant model.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110601
Title: Decrease in transient receptor potential melastatin 6 mRNA stability caused by rapamycin in renal tubular epithelial cells.
Journal: Biochimica et biophysica acta 20110601
Title: Expansion of CD4(+)CD25 (+) regulatory T cells from cord blood CD4(+) cells using the common γ-chain cytokines (IL-2 and IL-15) and rapamycin.
Journal: Annals of hematology 20110601
Title: Clinical and molecular insights into tuberous sclerosis complex renal disease.
Journal: Pediatric nephrology (Berlin, Germany) 20110601
Title: Endothelium-dependent coronary vasomotor response and neointimal coverage of zotarolimus-eluting stents 3 months after implantation.
Journal: Heart (British Cardiac Society) 20110601
Title: Poly(ethylene glycol)-block-poly(2-methyl-2-benzoxycarbonyl-propylene carbonate) micelles for rapamycin delivery: in vitro characterization and biodistribution.
Journal: Journal of pharmaceutical sciences 20110601
Title: Recent developments in drug-eluting stents.
Journal: Journal of molecular medicine (Berlin, Germany) 20110601
Title: Temsirolimus in advanced leiomyosarcomas: patterns of response and correlation with the activation of the mammalian target of rapamycin pathway.
Journal: Anti-cancer drugs 20110601
Title: Targeting glycolysis in leukemia: a novel inhibitor 3-BrOP in combination with rapamycin.
Journal: Leukemia research 20110601
Title: PDGF-induced vascular smooth muscle cell proliferation is associated with dysregulation of insulin receptor substrates.
Journal: American journal of physiology. Cell physiology 20110601
Title: Five-year experience using sirolimus-based, calcineurin inhibitor-free immunosuppression in pediatric renal transplantation.
Journal: Pediatric transplantation 20110601
Title: Growth of kidney-transplanted pediatric patients treated with sirolimus.
Journal: Pediatric nephrology (Berlin, Germany) 20110601
Title: Efficacy of ganitumab (AMG 479), alone and in combination with rapamycin, in Ewing's and osteogenic sarcoma models.
Journal: The Journal of pharmacology and experimental therapeutics 20110601
Title: Complete induction of autophagy is essential for cardioprotection in sepsis.
Journal: Annals of surgery 20110601
Title: Dramatic tumor response to everolimus for malignant epithelioid angiomyolipoma.
Journal: Japanese journal of clinical oncology 20110601
Title: mTOR complex 2 activation by reconstituted high-density lipoprotein prevents senescence in circulating angiogenic cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20110601
Title: Autophagy protects against aminochrome-induced cell death in substantia nigra-derived cell line.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110601
Title: mTOR inhibition, a potential novel approach for bronchial carcinoids.
Journal: Endocrine-related cancer 20110601
Title: The real world experience of the everolimus-eluting coronary stent system: audit of everolimus-eluting coronary stents.
Journal: Journal of interventional cardiology 20110601
Title: Effects of rapamycin and TOR on aging and memory: implications for Alzheimer's disease.
Journal: Journal of neurochemistry 20110601
Title: [Collecting duct renal cell carcinoma].
Journal: Actas urologicas espanolas 20110601
Title: Impact of combined HDAC and mTOR inhibition on adhesion, migration and invasion of prostate cancer cells.
Journal: Clinical & experimental metastasis 20110601
Title: Adiponectin induces vascular smooth muscle cell differentiation via repression of mammalian target of rapamycin complex 1 and FoxO4.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20110601
Title: The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells.
Journal: Cancer biology & therapy 20110601
Title: Mammalian target of rapamycin expression in poorly differentiated endocrine carcinoma: clinical and therapeutic future challenges.
Journal: Targeted oncology 20110601
Title: Acid β-glucosidase mutants linked to Gaucher disease, Parkinson disease, and Lewy body dementia alter α-synuclein processing.
Journal: Annals of neurology 20110601
Title: Treatment of metastatic renal cell carcinoma and renal pelvic cancer.
Journal: Clinical and experimental nephrology 20110601
Title: Management of adverse events associated with the use of everolimus in patients with advanced renal cell carcinoma.
Journal: European journal of cancer (Oxford, England : 1990) 20110601
Title: Impaired autophagy: a link between neurodegenerative diseases and progressive myoclonus epilepsies.
Journal: Trends in molecular medicine 20110601
Title: Everolimus induces rapid plasma glucose normalization in insulinoma patients by effects on tumor as well as normal tissues.
Journal: The oncologist 20110601
Title: Ridaforolimus (AP23573; MK-8669), a potent mTOR inhibitor, has broad antitumor activity and can be optimally administered using intermittent dosing regimens.
Journal: Molecular cancer therapeutics 20110601
Title: Everolimus augments the effects of sorafenib in a syngeneic orthotopic model of hepatocellular carcinoma.
Journal: Molecular cancer therapeutics 20110601
Title: An intein-cassette integration approach used for the generation of a split TEV protease activated by conditional protein splicing.
Journal: Molecular bioSystems 20110601
Title: Chemotherapy-related bilateral dermatitis associated with eccrine squamous syringometaplasia: reappraisal of epidemiological, clinical, and pathological features.
Journal: Journal of the American Academy of Dermatology 20110601
Title: Common toxicities of mammalian target of rapamycin inhibitors.
Journal: Targeted oncology 20110601
Title: Bone healing after secondary surgery on hand allografts under sirolimus-based maintenance immunosuppression.
Journal: Annals of plastic surgery 20110601
Title: Predictive biomarkers for the activity of mammalian target of rapamycin (mTOR) inhibitors.
Journal: Targeted oncology 20110601
Title: Long-term outcomes of sirolimus-eluting stents vs. paclitaxel-eluting stents in unprotected left main coronary artery bifurcation lesions.
Journal: Clinical cardiology 20110601
Title: Clinical activity of mammalian target of rapamycin inhibitors in solid tumors.
Journal: Targeted oncology 20110601
Title: Targeting phosphatidylinositol 3 kinase (PI3K)-Akt beyond rapalogs.
Journal: Targeted oncology 20110601
Title: Generation and large-scale expansion of human inducible regulatory T cells that suppress graft-versus-host disease.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110601
Title: mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry.
Journal: Genes & development 20110601
Title: Impact of polymer formulations on neointimal proliferation after zotarolimus-eluting stent with different polymers: insights from the RESOLUTE trial.
Journal: Circulation. Cardiovascular interventions 20110601
Title: The role of sirolimus in the prevention of cutaneous squamous cell carcinoma in organ transplant recipients.
Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20110601
Title: Role of mTOR in podocyte function and diabetic nephropathy in humans and mice.
Journal: The Journal of clinical investigation 20110601
Title: mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice.
Journal: The Journal of clinical investigation 20110601
Title: The targeted podocyte.
Journal: The Journal of clinical investigation 20110601
Title: Hypoxia-induced ROS signaling is required for LOX up-regulation in endothelial cells.
Journal: Frontiers in bioscience (Elite edition) 20110601
Title: Sirolimus: not so sparing in the Spare-the-Nephron trial.
Journal: Kidney international 20110601
Title: Temsirolimus in relapsed and/or refractory mantle cell lymphoma†: profile report.
Journal: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20110601
Title: Posttransplant distal limb syndrome.
Journal: The Journal of orthopaedic and sports physical therapy 20110601
Title: No role for early IGF-1 signalling in stimulating acute 'muscle building' responses.
Journal: The Journal of physiology 20110601
Title: The isomerase Rrd1 mediates rapid loss of the Sgs1 helicase in response to rapamycin.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20110601
Title: The possibility of delayed arterial healing 5 years after implantation of sirolimus-eluting stents: serial observations by coronary angioscopy.
Journal: American heart journal 20110601
Title: Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling.
Journal: The American journal of pathology 20110601
Title: Are we ready to move away from nature?: the rapamycin story.
Journal: Targeted oncology 20110601
Title: Enhanced efficacy of sirolimus-eluting bioabsorbable magnesium alloy stents in the prevention of restenosis.
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20110601
Title: Commentary: Deliver the drug and disappear: is the bioabsorbable magnesium stent growing up or still shrinking?
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20110601
Title: Sirolimus therapy predisposes to new-onset diabetes mellitus after renal transplantation: a long-term analysis of various treatment regimens.
Journal: Transplantation proceedings 20110601
Title: Vascular endothelial function of sirolimus maintenance regimen in renal transplant recipients.
Journal: Transplantation proceedings 20110601
Title: Laparoscopic incisional hernia repair after solid-organ transplantation.
Journal: Transplantation proceedings 20110601
Title: Everolimus plus dosage reduction of cyclosporine in cardiac transplant recipients with chronic kidney disease: a two-year follow-up study.
Journal: Transplantation proceedings 20110601
Title: Calcineurin inhibitor-free immunosuppression using everolimus (Certican) after heart transplantation: 2 years' follow-up from the University Hospital Münster.
Journal: Transplantation proceedings 20110601
Title: Efficacy and safety of sirolimus and everolimus in heart transplant patients: a retrospective analysis.
Journal: Transplantation proceedings 20110601
Title: Long-term maintenance therapy for post-cardiac transplant monoclonal lymphoproliferative disorder: caveat mammalian target of rapamycin.
Journal: Transplantation proceedings 20110601
Title: Local application of rapamycin inhibits vein graft restenosis in rabbits.
Journal: Transplantation proceedings 20110601
Title: Comparison of titanium-nitride-oxide-coated stents with zotarolimus-eluting stents for coronary revascularization a randomized controlled trial.
Journal: JACC. Cardiovascular interventions 20110601
Title: Paclitaxel-eluting balloons for sirolimus-eluting stent restenosis.
Journal: JACC. Cardiovascular interventions 20110601
Title: In-stent restenosis after revascularization of myocardium with drug-eluting stents is accompanied by elevated level of blood plasma eosinophil cationic protein.
Journal: Canadian journal of physiology and pharmacology 20110601
Title: Incidence, risk factors, and clinical sequelae of angiographic peri-stent contrast staining after sirolimus-eluting stent implantation.
Journal: Circulation 20110531
Title: The impact of patient and lesion complexity on clinical and angiographic outcomes after revascularization with zotarolimus- and everolimus-eluting stents: a substudy of the RESOLUTE All Comers Trial (a randomized comparison of a zotarolimus-eluting stent with an everolimus-eluting stent for percutaneous coronary intervention).
Journal: Journal of the American College of Cardiology 20110531
Title: Hormonally active vitamin D3 (1alpha,25-dihydroxycholecalciferol) triggers autophagy in human macrophages that inhibits HIV-1 infection.
Journal: The Journal of biological chemistry 20110527
Title: Prospective study of everolimus with calcineurin inhibitor-free immunosuppression in maintenance heart transplant patients: results at 2 years.
Journal: Transplantation 20110527
Title: Everolimus and minimization of cyclosporine in renal transplantation: 24-month follow-up of the EVEREST study.
Journal: Transplantation 20110527
Title: Genetic and clinical risk factors of new-onset diabetes after transplantation in Hispanic kidney transplant recipients.
Journal: Transplantation 20110527
Title: Long-term comparison of everolimus-eluting and sirolimus-eluting stents for coronary revascularization.
Journal: Journal of the American College of Cardiology 20110524
Title: Akt/mammalian target of rapamycin signaling pathway regulates neurite outgrowth in cerebellar granule neurons stimulated by methylcobalamin.
Journal: Neuroscience letters 20110520
Title: The long and winding road to rational treatment of cancer associated with LKB1/AMPK/TSC/mTORC1 signaling.
Journal: Oncogene 20110519
Title: Combination of direct and adjusted indirect comparisons of sirolimus- versus paclitaxel-eluting stents for ST-segment elevation myocardial infarction.
Journal: International journal of cardiology 20110519
Title: [Effects of sirolimus upon endothelial thrombotic function of human umbilical vein endothelial cells].
Journal: Zhonghua yi xue za zhi 20110517
Title: Targeting the JNK signaling pathway potentiates the antiproliferative efficacy of rapamycin in LS174T colon cancer cells.
Journal: The Journal of surgical research 20110515
Title: Sirolimus and proteinuria in renal transplant patients: evidence for a dose-dependent effect on slit diaphragm-associated proteins.
Journal: Transplantation 20110515
Title: Successful pregnancy in a living-related kidney transplant recipient who received sirolimus throughout the whole gestation.
Journal: Transplantation 20110515
Title: Advances in pancreatic neuroendocrine tumor treatment.
Journal: The New England journal of medicine 20110512
Title: Everolimus- and temsirolimus-associated enteritis: report of three cases.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110510
Title: Phosphomimetic substitution of heterogeneous nuclear ribonucleoprotein A1 at serine 199 abolishes AKT-dependent internal ribosome entry site-transacting factor (ITAF) function via effects on strand annealing and results in mammalian target of rapamycin complex 1 (mTORC1) inhibitor sensitivity.
Journal: The Journal of biological chemistry 20110506
Title: Randomized trial of stents versus bypass surgery for left main coronary artery disease.
Journal: The New England journal of medicine 20110505
Title: Everolimus interferes with the inflammatory phase of healing in experimental colonic anastomoses.
Journal: The Journal of surgical research 20110501
Title: Biodegradable sirolimus-loaded poly(lactide) nanoparticles as drug delivery system for the prevention of in-stent restenosis in coronary stent application.
Journal: Journal of biomaterials applications 20110501
Title: Rapamycin suppresses ROS-dependent apoptosis caused by selenomethionine in A549 lung carcinoma cells.
Journal: Cancer chemotherapy and pharmacology 20110501
Title: Therapy of sclerodermatous chronic graft-versus-host disease with mammalian target of rapamycin inhibitors.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110501
Title: Double umbilical cord blood transplantation with reduced intensity conditioning and sirolimus-based GVHD prophylaxis.
Journal: Bone marrow transplantation 20110501
Title: Strategies to prevent EBV reactivation and posttransplant lymphoproliferative disorders (PTLD) after allogeneic stem cell transplantation in high-risk patients.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110501
Title: Evaluation of sphingolipid metabolism in renal cortex of rats with streptozotocin-induced diabetes and the effects of rapamycin.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110501
Title: The 5352 A allele of the pro-inflammatory caspase-1 gene predicts late-acquired stent malapposition in STEMI patients treated with sirolimus stents.
Journal: Heart and vessels 20110501
Title: Adoptive transfer of CD4+CD25+ regulatory cells combined with low-dose sirolimus and anti-thymocyte globulin delays acute rejection of renal allografts in Cynomolgus monkeys.
Journal: International immunopharmacology 20110501
Title: Generation of human regulatory T cells de novo with suppressive function prevent xenogeneic graft versus host disease.
Journal: International immunopharmacology 20110501
Title: Somatostatin analogues for treatment of polycystic liver disease.
Journal: Current opinion in gastroenterology 20110501
Title: Predictors of long-term renal function after conversion to proliferation signal inhibitors in long-term heart transplant recipients.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20110501
Title: GSK3β inactivation in podocytes results in decreased phosphorylation of p70S6K accompanied by cytoskeletal rearrangements and inhibited motility.
Journal: American journal of physiology. Renal physiology 20110501
Title: Differential effects of rapamycin on rods and cones during light-induced stress in albino mice.
Journal: Investigative ophthalmology & visual science 20110501
Title: Costimulatory blockade with mTor inhibition abrogates effector T-cell responses allowing regulatory T-cell survival in renal transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20110501
Title: Visfatin exerts angiogenic effects on human umbilical vein endothelial cells through the mTOR signaling pathway.
Journal: Biochimica et biophysica acta 20110501
Title: Targeted inhibition of mTORC1 and mTORC2 by active-site mTOR inhibitors has cytotoxic effects in T-cell acute lymphoblastic leukemia.
Journal: Leukemia 20110501
Title: Lack of compensatory pAKT activation and eIF4E phosphorylation of lymphoma cells towards mTOR inhibitor, RAD001.
Journal: European journal of cancer (Oxford, England : 1990) 20110501
Title: Rapamycin treatment augments both protein ubiquitination and Akt activation in pressure-overloaded rat myocardium.
Journal: American journal of physiology. Heart and circulatory physiology 20110501
Title: Rapamycin inhibits hydrogen peroxide-induced loss of vascular contractility.
Journal: American journal of physiology. Heart and circulatory physiology 20110501
Title: Temsirolimus inhibits malignant pleural mesothelioma growth in vitro and in vivo: synergism with chemotherapy.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110501
Title: AMPK and substrate availability regulate creatine transport in cultured cardiomyocytes.
Journal: American journal of physiology. Endocrinology and metabolism 20110501
Title: The antagonist of the JAK-1/STAT-1 signaling pathway improves the severity of cerulein-stimulated pancreatic injury via inhibition of NF-κB activity.
Journal: International journal of molecular medicine 20110501
Title: Five-year clinical follow-up after sirolimus-eluting stent implantation for the treatment of coronary in-stent restenosis.
Journal: Coronary artery disease 20110501
Title: Effects of mTOR inhibitor everolimus (RAD001) on bladder cancer cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110501
Title: The mTOR-targeting drug temsirolimus enhances the growth-inhibiting effects of the cetuximab-bevacizumab-irradiation combination on head and neck cancer xenografts.
Journal: Oral oncology 20110501
Title: The potential benefits and risks of the use of dual antiplatelet therapy beyond 6 months following sirolimus-eluting stent implantation for low-risk patients.
Journal: Journal of cardiology 20110501
Title: Drug-related pneumonitis in patients with advanced renal cell carcinoma treated with temsirolimus.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110501
Title: Patient-reported outcomes in a phase iii study of everolimus versus placebo in patients with metastatic carcinoma of the kidney that has progressed on vascular endothelial growth factor receptor tyrosine kinase inhibitor therapy.
Journal: The oncologist 20110501
Title: Secreted factors from brain endothelial cells maintain glioblastoma stem-like cell expansion through the mTOR pathway.
Journal: EMBO reports 20110501
Title: Regression of a cardiac rhabdomyoma in a patient receiving everolimus.
Journal: Pediatrics 20110501
Title: Clinical outcomes by geographic region for patients implanted with the zotarolimus-eluting stent.
Journal: Arquivos brasileiros de cardiologia 20110501
Title: Everolimus for the treatment of advanced renal cell carcinoma.
Journal: Expert opinion on pharmacotherapy 20110501
Title: The cutaneous effects of post-transplant immunosuppression with cyclosporine in Muir-Torre syndrome.
Journal: Journal of the American Academy of Dermatology 20110501
Title: Efficacy and comparative effectiveness of sirolimus as an anticancer drug.
Journal: The Laryngoscope 20110501
Title: CD40-specific costimulation blockade enhances neonatal porcine islet survival in nonhuman primates.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110501
Title: Ex vivo transfer of adenovirus-mediated CTLA4Ig gene combined with a short course of rapamycin therapy prolongs free flap allograft survival.
Journal: Plastic and reconstructive surgery 20110501
Title: Rapamycin-loaded nanoparticles for inhibition of neointimal hyperplasia in experimental vein grafts.
Journal: Annals of vascular surgery 20110501
Title: Predictors of death or myocardial infarction, ischaemic-driven revascularisation, and major adverse cardiovascular events following everolimus-eluting or paclitaxel-eluting stent deployment: pooled analysis from the SPIRIT II, III, IV and COMPARE trials.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501
Title: PLATINUM QCA: a prospective, multicentre study assessing clinical, angiographic, and intravascular ultrasound outcomes with the novel platinum chromium thin-strut PROMUS Element everolimus-eluting stent in de novo coronary stenoses.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501
Title: Impact of drug-eluting stent type on periprocedural myocardial necrosis.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501
Title: Rationale and design of the clinical evaluation of the Resolute Zotarolimus-Eluting Coronary Stent System in the treatment of de novo lesions in native coronary arteries (the RESOLUTE US clinical trial).
Journal: American heart journal 20110501
Title: Late-term clinical outcomes with zotarolimus- and sirolimus-eluting stents. 5-year follow-up of the ENDEAVOR III (A Randomized Controlled Trial of the Medtronic Endeavor Drug [ABT-578] Eluting Coronary Stent System Versus the Cypher Sirolimus-Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions).
Journal: JACC. Cardiovascular interventions 20110501
Title: My stent is better than your stent...Or is it?
Journal: JACC. Cardiovascular interventions 20110501
Title: Usefulness of rotational atherectomy in preventing polymer damage of everolimus-eluting stent in calcified coronary artery.
Journal: JACC. Cardiovascular interventions 20110501
Title: Experimental study of the anticancer effect of gemcitabine combined with sirolimus on chemically induced urothelial lesions.
Journal: Anticancer research 20110501
Title: Once-a-day administration of everolimus is safe in de novo renal transplant recipients: 1-year results of a pilot study.
Journal: Transplantation proceedings 20110501
Title: University of Modena experience in HIV-positive patients undergoing liver transplantation.
Journal: Transplantation proceedings 20110501
Title: Causes of sirolimus discontinuation in 97 liver transplant recipients.
Journal: Transplantation proceedings 20110501
Title: Incisional hernia after simultaneous pancreas kidney tranplantation: a single-center experience from Budapest.
Journal: Transplantation proceedings 20110501
Title: Coactivation of receptor tyrosine kinases in malignant mesothelioma as a rationale for combination targeted therapy.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110501
Title: Optical coherence tomography (OCT) in PCI for in-stent restenosis (ISR): rationale and design of the SEDUCE (Safety and Efficacy of a Drug elUting balloon in Coronary artery rEstenosis) study.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501
Title: Local drug delivery - the early Berlin experience: single drug administration versus sustained release.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501
Title: Paclitaxel and sirolimus differentially affect growth and motility of endothelial progenitor cells and coronary artery smooth muscle cells.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501
Title: A prospective randomised study using optical coherence tomography to assess endothelial coverage and neointimal proliferation at 6-months after implantation of a coronary everolimus-eluting stent compared with a bare metal stent postdilated with a paclitaxel-eluting balloon (OCTOPUS Trial): rationale, design and methods.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501
Title: Patient organizations and research on rare diseases.
Journal: The New England journal of medicine 20110428
Title: Efficacy and safety of sirolimus in lymphangioleiomyomatosis.
Journal: The New England journal of medicine 20110428
Title: Clinical evaluation of the Resolute zotarolimus-eluting coronary stent system in the treatment of de novo lesions in native coronary arteries: the RESOLUTE US clinical trial.
Journal: Journal of the American College of Cardiology 20110426
Title: Isolation and structure of homotemsirolimuses A, B, and C.
Journal: Journal of natural products 20110425
Title: [Novelties in the treatment for advanced renal-cell cancer].
Journal: Orvosi hetilap 20110424
Title: The inhibition of MAPK potentiates the anti-angiogenic efficacy of mTOR inhibitors.
Journal: Biochemical and biophysical research communications 20110422
Title: Inhibition of mTOR blocks the anti-inflammatory effects of glucocorticoids in myeloid immune cells.
Journal: Blood 20110421
Title: Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection.
Journal: Cell host & microbe 20110421
Title: Response of lymphangioleiomyomatosis to a mammalian target of rapamycin inhibitor (temsirolimus) -based treatment.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110420
Title: Recent studies show promise for treating rare pancreatic tumors.
Journal: Journal of the National Cancer Institute 20110420
Title: A prospective, randomized evaluation of a novel everolimus-eluting coronary stent: the PLATINUM (a Prospective, Randomized, Multicenter Trial to Assess an Everolimus-Eluting Coronary Stent System [PROMUS Element] for the Treatment of Up to Two de Novo Coronary Artery Lesions) trial.
Journal: Journal of the American College of Cardiology 20110419
Title: Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure.
Journal: Biological psychiatry 20110415
Title: Comparison of three-year clinical outcomes after sirolimus-eluting stent implantation among insulin-treated diabetic, non-insulin-treated diabetic, and non-diabetic patients from j-Cypher registry.
Journal: The American journal of cardiology 20110415
Title: Rapamycin impairs proliferation of transplanted islet β cells.
Journal: Transplantation 20110415
Title: Generation of adaptive regulatory T cells by alloantigen is required for some but not all transplant tolerance protocols.
Journal: Transplantation 20110415
Title: Ex vivo rapamycin treatment of human cord blood CD34+ cells enhances their engraftment of NSG mice.
Journal: Blood cells, molecules & diseases 20110415
Title: Th17 cells in alemtuzumab-treated patients: the effect of long-term maintenance immunosuppressive therapy.
Journal: Transplantation 20110415
Title: Identification and elimination of ion suppression in the quantitative analysis of sirolimus in human blood by LC/ESI-MS/MS.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110415
Title: An accurate quantitative LC/ESI-MS/MS method for sirolimus in human whole blood.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110415
Title: Clinical outcome, angiographic outcome, and coronary endothelial function after drug-eluting stent implantation.
Journal: Journal of the American College of Cardiology 20110412
Title: Unrestricted randomised use of two new generation drug-eluting coronary stents: 2-year patient-related versus stent-related outcomes from the RESOLUTE All Comers trial.
Journal: Lancet (London, England) 20110409
Title: Long-term safety and efficacy of drug-eluting stents.
Journal: Lancet (London, England) 20110409
Title: WIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition.
Journal: The Journal of biological chemistry 20110408
Title: A phase II study of everolimus in combination with imatinib for previously treated advanced renal carcinoma.
Journal: Investigational new drugs 20110401
Title: Melanoma: from darkness to promise.
Journal: American journal of clinical oncology 20110401
Title: Complete fracture and migration of a coronary sirolimus-eluting stent.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20110401
Title: An investigation of reversal of imatinib resistance in the Bcr-Abl positive imatinib-resistant cell line K562r by dasatinib, nilotinib, rapamycin and bortezomib.
Journal: International journal of laboratory hematology 20110401
Title: The pharmacokinetics of Biolimus A9 after elution from the BioMatrix II stent in patients with coronary artery disease: the Stealth PK Study.
Journal: European journal of clinical pharmacology 20110401
Title: A high-throughput fluorescence chemical denaturation assay as a general screen for protein-ligand binding.
Journal: Analytical biochemistry 20110401
Title: Bfl-1/A1 acts as a negative regulator of autophagy in mycobacteria infected macrophages.
Journal: The international journal of biochemistry & cell biology 20110401
Title: Development and characterization of clinically relevant tumor models from patients with renal cell carcinoma.
Journal: European urology 20110401
Title: Hot topics in aging research: protein translation and TOR signaling, 2010.
Journal: Aging cell 20110401
Title: Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein.
Journal: Autophagy 20110401
Title: Mycophenolate mofetil-based immunosuppression with sirolimus in renal transplantation: a randomized, controlled Spare-the-Nephron trial.
Journal: Kidney international 20110401
Title: Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
Journal: Autophagy 20110401
Title: Comparison of haemodialysis patients and non-haemodialysis patients with respect to clinical characteristics and 3-year clinical outcomes after sirolimus-eluting stent implantation: insights from the Japan multi-centre post-marketing surveillance registry.
Journal: European heart journal 20110401
Title: Late catch-up phenomenon associated with stent fracture after sirolimus-eluting stent implantation: incidence and outcome.
Journal: Journal of interventional cardiology 20110401
Title: Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin.
Journal: Human molecular genetics 20110401
Title: Volumetric analysis of MRI data monitoring the treatment of polycystic kidney disease in a mouse model.
Journal: Magma (New York, N.Y.) 20110401
Title: Zymosan suppresses leukotriene C₄ synthase activity in differentiating monocytes: antagonism by aspirin and protein kinase inhibitors.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110401
Title: Oleate-mediated activation of phospholipase D and mammalian target of rapamycin (mTOR) regulates proliferation and rapamycin sensitivity of hepatocarcinoma cells.
Journal: Diabetologia 20110401
Title: Evaluation of QMS everolimus assay using Hitachi 917 Analyzer: comparison with liquid chromatography/mass spectrometry.
Journal: Therapeutic drug monitoring 20110401
Title: Targeting of active mTOR inhibits primary leukemia T cells and synergizes with cytotoxic drugs and signaling inhibitors.
Journal: Experimental hematology 20110401
Title: Secretion of three enzymes for fatty acid synthesis into mouse milk in association with fat globules, and rapid decrease of the secreted enzymes by treatment with rapamycin.
Journal: Archives of biochemistry and biophysics 20110401
Title: Rapamycin reverses splenomegaly and inhibits tumor development in a transgenic model of Epstein-Barr virus-related Burkitt's lymphoma.
Journal: Molecular cancer therapeutics 20110401
Title: The Akt-specific inhibitor MK2206 selectively inhibits thyroid cancer cells harboring mutations that can activate the PI3K/Akt pathway.
Journal: The Journal of clinical endocrinology and metabolism 20110401
Title: Microstructure and drug-release studies of sirolimus-containing poly(lactide-co-glycolide) films.
Journal: Journal of biomedical materials research. Part B, Applied biomaterials 20110401
Title: Inhibition by rapamycin of the lipoteichoic acid-induced granulocyte-colony stimulating factor expression in mouse macrophages.
Journal: Archives of biochemistry and biophysics 20110401
Title: The novel Raf inhibitor Raf265 decreases Bcl-2 levels and confers TRAIL-sensitivity to neuroendocrine tumour cells.
Journal: Endocrine-related cancer 20110401
Title: The identification of raptor as a substrate for p44/42 MAPK.
Journal: Endocrinology 20110401
Title: Targeting the mTOR kinase domain: the second generation of mTOR inhibitors.
Journal: Drug discovery today 20110401
Title: Imidazo[1,5-a]pyrazines: orally efficacious inhibitors of mTORC1 and mTORC2.
Journal: Bioorganic & medicinal chemistry letters 20110401
Title: Novel approaches for preventing or limiting events in diabetic patients (Naples-diabetes) trial: a randomized comparison of 3 drug-eluting stents in diabetic patients.
Journal: Circulation. Cardiovascular interventions 20110401
Title: Comparison of zotarolimus-eluting stents with sirolimus-eluting and paclitaxel-eluting stents: intimal hyperplasia and vascular changes assessed by volumetric intravascular ultrasound analysis.
Journal: Circulation. Cardiovascular interventions 20110401
Title: Rapamycin-mediated mTOR inhibition attenuates survivin and sensitizes glioblastoma cells to radiation therapy.
Journal: Acta biochimica et biophysica Sinica 20110401
Title: Intravascular ultrasound results from the NEVO ResElution-I trial: a randomized, blinded comparison of sirolimus-eluting NEVO stents with paclitaxel-eluting TAXUS Liberté stents in de novo native coronary artery lesions.
Journal: Circulation. Cardiovascular interventions 20110401
Title: The physiology and pathophysiology of rapamycin resistance: implications for cancer.
Journal: Cell cycle (Georgetown, Tex.) 20110401
Title: A brief history of TOR.
Journal: Biochemical Society transactions 20110401
Title: Differing effects of rapamycin and mTOR kinase inhibitors on protein synthesis.
Journal: Biochemical Society transactions 20110401
Title: Blocking the mTOR pathway: a drug discovery perspective.
Journal: Biochemical Society transactions 20110401
Title: Benefits of mTOR kinase targeting in oncology: pre-clinical evidence with AZD8055.
Journal: Biochemical Society transactions 20110401
Title: A critical role for non-coding RNA GAS5 in growth arrest and rapamycin inhibition in human T-lymphocytes.
Journal: Biochemical Society transactions 20110401
Title: Fragile X mental retardation protein regulates heterosynaptic plasticity in the hippocampus.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20110401
Title: Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: a phase 2 study.
Journal: The Lancet. Oncology 20110401
Title: New combinations for mantle cell lymphoma: concerted action needed.
Journal: The Lancet. Oncology 20110401
Title: Paradoxical aspects of rapamycin immunobiology in transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110401
Title: Two drug interaction studies of sirolimus in combination with sorafenib or sunitinib in patients with advanced malignancies.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110401
Title: Can the nephron be spared?
Journal: Kidney international 20110401
Title: [Treatment of metastatic renal cell carcinoma].
Journal: Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20110401
Title: Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy.
Journal: The Journal of clinical investigation 20110401
Title: Vulnerable plaque inside stent.
Journal: JACC. Cardiovascular imaging 20110401
Title: Restenosis: delineating the numerous causes of drug-eluting stent restenosis.
Journal: Circulation. Cardiovascular interventions 20110401
Title: The prognostic utility of the SYNTAX score on 1-year outcomes after revascularization with zotarolimus- and everolimus-eluting stents: a substudy of the RESOLUTE All Comers Trial.
Journal: JACC. Cardiovascular interventions 20110401
Title: Randomized comparison of a polymer-free sirolimus-eluting stent versus a polymer-based paclitaxel-eluting stent in patients with diabetes mellitus: the LIPSIA Yukon trial.
Journal: JACC. Cardiovascular interventions 20110401
Title: Five-year outcomes of percutaneous coronary intervention compared to bypass surgery in patients with multivessel disease involving the proximal left anterior descending artery: an ARTS-II sub-study.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110401
Title: Comparison between the first and second generation bioresorbable vascular scaffolds: a six month virtual histology study.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110401
Title: [Late thrombosis of sirolimus-eluting stent occurring in the perioperative period].
Journal: Masui. The Japanese journal of anesthesiology 20110401
Title: [Use of mTOR-inhibitors in solid tumors].
Journal: Medizinische Monatsschrift fur Pharmazeuten 20110401
Title: Comparison of long-term clinical outcome after successful implantation of FIREBIRD and CYPHER sirolimus-eluting stents in daily clinical practice: analysis of a large single-center registry.
Journal: Chinese medical journal 20110401
Title: Technical difficulty in stenting Supralimus in radial artery graft.
Journal: Arquivos brasileiros de cardiologia 20110401
Title: [Effect of rapamycin combined with cisplatin on head and neck squamous cancer cells regulated by CCL19].
Journal: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20110401
Title: mTOR inhibitors in the treatment of subependymal giant-cell astrocytomas associated with tuberous sclerosis.
Journal: Neurosurgery 20110401
Title: Ribosomal protein S6 is highly expressed in non-Hodgkin lymphoma and associates with mRNA containing a 5' terminal oligopyrimidine tract.
Journal: Oncogene 20110331
Title: Targeting the autophagy pathway using ectopic expression of Beclin 1 in combination with rapamycin in drug-resistant v-Ha-ras-transformed NIH 3T3 cells.
Journal: Molecules and cells 20110331
Title: Stent thrombosis and bleeding complications after implantation of sirolimus-eluting coronary stents in an unselected worldwide population: a report from the e-SELECT (Multi-Center Post-Market Surveillance) registry.
Journal: Journal of the American College of Cardiology 20110329
Title: Paclitaxel/sirolimus combination coated drug-eluting stent: in vitro and in vivo drug release studies.
Journal: Journal of pharmaceutical and biomedical analysis 20110325
Title: Drug-eluting or bare-metal stents in large coronary arteries.
Journal: The New England journal of medicine 20110324
Title: Chromophobe renal cell carcinoma with prolonged response to sequential sunitinib and everolimus.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110320
Title: Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation.
Journal: The Journal of biological chemistry 20110318
Title: Translational medicine: Cancer lessons from mice to humans.
Journal: Nature 20110317
Title: Long-term (three-year) safety and efficacy of everolimus-eluting stents compared to paclitaxel-eluting stents (from the SPIRIT III Trial).
Journal: The American journal of cardiology 20110315
Title: Three-year results of safety and efficacy of the everolimus-eluting coronary stent in women (from the SPIRIT III randomized clinical trial).
Journal: The American journal of cardiology 20110315
Title: MAP kinase-interacting kinase 1 regulates SMAD2-dependent TGF-β signaling pathway in human glioblastoma.
Journal: Cancer research 20110315
Title: Engineering the ABA plant stress pathway for regulation of induced proximity.
Journal: Science signaling 20110315
Title: [Rapamycin-mediated interaction of spleen γδT lymphocytes and lung macrophages in acute lung injury of mice induced by lipopolysaccharide].
Journal: Zhonghua yi xue za zhi 20110315
Title: Sindbis virus replication, is insensitive to rapamycin and torin1, and suppresses Akt/mTOR pathway late during infection in HEK cells.
Journal: Biochemical and biophysical research communications 20110311
Title: Pancreatic neuroendocrine tumors: role of novel agents. Highlights from the '2011 ASCO Gastrointestinal Cancers Symposium'. San Francisco, CA, USA. January 20-22, 2011.
Journal: JOP : Journal of the pancreas 20110309
Title: Everolimus-based, calcineurin-inhibitor-free regimen in recipients of de-novo kidney transplants: an open-label, randomised, controlled trial.
Journal: Lancet (London, England) 20110305
Title: Immunosuppression without calcineurin inhibition: by ZEUS.
Journal: Lancet (London, England) 20110305
Title: Stent fracture and restenosis after zotarolimus-eluting stent implantation.
Journal: International journal of cardiology 20110303
Title: Long-term safety and efficacy of sirolimus- vs. paclitaxel-eluting stent implantation for acute ST-elevation myocardial infarction: 3-year follow-up of the PROSIT trial.
Journal: International journal of cardiology 20110303
Title: Autophagy modification augmented the treatment effects initiated by arsenic trioxide in NB4 cells.
Journal: Medical oncology (Northwood, London, England) 20110301
Title: Leucine supplementation in rats induced a delay in muscle IR/PI3K signaling pathway associated with overall impaired glucose tolerance.
Journal: The Journal of nutritional biochemistry 20110301
Title: Comparative assessment of mammalian target of rapamycin inhibitor-eluting stents in the treatment of coronary artery bifurcation lesions: the CASTOR-Bifurcation registry.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110301
Title: Hypoxia-inducible factor and mammalian target of rapamycin pathway markers in urothelial carcinoma of the bladder: possible therapeutic implications.
Journal: BJU international 20110301
Title: Radiologic complete response with sirolimus and sorafenib in a hepatocellular carcinoma patient who relapsed after orthotopic liver transplantation.
Journal: Journal of gastrointestinal cancer 20110301
Title: Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic β-cells: protective role of p62-positive cytoplasmic inclusions.
Journal: Cell death and differentiation 20110301
Title: Leukemias induced by altered TRK-signaling are sensitive to mTOR inhibitors in preclinical models.
Journal: Annals of hematology 20110301
Title: Five-year clinical outcomes of sirolimus-eluting versus paclitaxel-eluting stents in high-risk patients.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110301
Title: Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin.
Journal: Disease models & mechanisms 20110301
Title: Long-term angiographic outcomes of post-sirolimus-eluting stent restenosis in Japanese patients.
Journal: Heart and vessels 20110301
Title: mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression.
Journal: Kidney international 20110301
Title: Rapamycin increases the yield and effector function of human γδ T cells stimulated in vitro.
Journal: Cancer immunology, immunotherapy : CII 20110301
Title: Angiographic late lumen loss at the site of overlap of multiple Cypher™ sirolimus-eluting stents: ALSOCE study.
Journal: Journal of cardiology 20110301
Title: Diaphragm rupture in a liver transplant patient under chronic immunosuppressive therapy with sirolimus: rare complication after liver transplantation.
Journal: Updates in surgery 20110301
Title: Pushing the envelope in the mTOR pathway: the second generation of inhibitors.
Journal: Molecular cancer therapeutics 20110301
Title: Heat stress enhances mTOR signaling after resistance exercise in human skeletal muscle.
Journal: The journal of physiological sciences : JPS 20110301
Title: The double-faced metabolic and inflammatory effects of standard drug therapy in patients after percutaneous treatment with drug-eluting stent.
Journal: Atherosclerosis 20110301
Title: mTOR inhibitors show promising in vitro activity in bladder cancer and head and neck squamous cell carcinoma.
Journal: Oncology reports 20110301
Title: mTOR couples cellular nutrient sensing to organismal metabolic homeostasis.
Journal: Trends in endocrinology and metabolism: TEM 20110301
Title: Regulatory T cells require mammalian target of rapamycin signaling to maintain both homeostasis and alloantigen-driven proliferation in lymphocyte-replete mice.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20110301
Title: Current and future directions in mammalian target of rapamycin inhibitors development.
Journal: Expert opinion on investigational drugs 20110301
Title: Biolimus-eluting biodegradable polymer-coated stent versus bare metal stent in acute ST-elevation and non-ST elevation myocardial infarction: Justification for biodegradable polymer-coated stent in acute coronary syndrome (JANICE) registry.
Journal: Acute cardiac care 20110301
Title: Cyclosporin A, but not everolimus, inhibits DNA repair mediated by calcineurin: implications for tumorigenesis under immunosuppression.
Journal: Experimental dermatology 20110301
Title: The outcome of bifurcation lesion stenting using a biolimus-eluting stent with a bio-degradable polymer compared to a sirolimus-eluting stent with a durable polymer.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110301
Title: Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation.
Journal: The Journal of clinical investigation 20110301
Title: Analytical and pharmacological aspects of therapeutic drug monitoring of mTOR inhibitors.
Journal: Current drug metabolism 20110301
Title: Sirolimus enhances the magnitude and quality of viral-specific CD8+ T-cell responses to vaccinia virus vaccination in rhesus macaques.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110301
Title: Weekly bortezomib in combination with temsirolimus in relapsed or relapsed and refractory multiple myeloma: a multicentre, phase 1/2, open-label, dose-escalation study.
Journal: The Lancet. Oncology 20110301
Title: If I've heard it once, I've heard it (not yet) a hundred times.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110301
Title: Primary percutaneous coronary intervention of an unprotected left main using mini-crush drug-eluting stents facilitated by intracoronary reteplase.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110301
Title: Noninfectious pneumonitis in a patient with renal cell carcinoma treated with everolimus.
Journal: Oncology nursing forum 20110301
Title: Reduced VEGF production, angiogenesis, and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors.
Journal: Cancer research 20110301
Title: Ruptured-plaque-like appearance of restenotic tissue following sirolimus-eluting stent implantation: an optical coherence tomography case study.
Journal: The Journal of invasive cardiology 20110301
Title: CYP3A5 genotype does not influence everolimus in vitro metabolism and clinical pharmacokinetics in renal transplant recipients.
Journal: Transplantation 20110301
Title: Potential of mTOR inhibitors for the treatment of subependymal giant cell astrocytomas in tuberous sclerosis complex.
Journal: Aging 20110301
Title: A randomized comparison of sirolimus- versus paclitaxel-eluting stent implantation in patients with diabetes mellitus: 4-year clinical outcomes of DES-DIABETES (drug-eluting stent in patients with DIABETES mellitus) trial.
Journal: JACC. Cardiovascular interventions 20110301
Title: Prospective randomized comparison of sirolimus- or everolimus-eluting stent to treat bifurcated lesions by provisional approach.
Journal: JACC. Cardiovascular interventions 20110301
Title: Steroid and calcineurin inhibitor-sparing protocols in kidney transplantation.
Journal: Transplantation proceedings 20110301
Title: Conversion to low-dose tacrolimus or rapamycin 3 months after kidney transplantation: a prospective, protocol biopsy-guided study.
Journal: Transplantation proceedings 20110301
Title: Rapamycin prevents interstitial fibrosis in renal allografts through decreasing angiogenesis and inflammation.
Journal: Transplantation proceedings 20110301
Title: Exploring long-term protection of normal human fibroblasts and epithelial cells from chemotherapy in cell culture.
Journal: Oncotarget 20110301
Title: Future directions of mammalian target of rapamycin (mTOR) inhibitor therapy in renal cell carcinoma.
Journal: Targeted oncology 20110301
Title: Spatial distribution of neo-intimal hyperplasia 6 months after zotarolimus-eluting stent implantation, analysed by optical coherence tomography.
Journal: Archives of cardiovascular diseases 20110301
Title: Mammalian target of rapamycin as a target in hematological malignancies.
Journal: Targeted oncology 20110301
Title: A prospective multicenter parallel-controlled trial of TIVOLI biodegradable-polymer-based sirolimus-eluting stent compared to ENDEAVOR zotarolimus-eluting stent for the treatment of coronary artery disease: 8-month angiographic and 2-year clinical follow-up results.
Journal: Chinese medical journal 20110301
Title: Efficacy and safety of Firebird sirolimus-eluting stent in treatment of complex coronary lesions in Chinese patients: one-year clinical and eight-month angiographic outcomes from the FIREMAN registry.
Journal: Chinese medical journal 20110301
Title: Six-month clinical outcomes of Firebird 2TM sirolimus-eluting stent implantation in real-world patients with coronary artery diseases.
Journal: Chinese medical journal 20110301
Title: Long-term effects of biodegradable versus durable polymer-coated sirolimus-eluting stents on coronary arterial wall morphology assessed by virtual histology intravascular ultrasound.
Journal: Chinese medical journal 20110301
Title: Targeting the target of rapamycin (TOR): looking to mother nature.
Journal: Targeted oncology 20110301
Title: The emerging role of mammalian target of rapamycin inhibitors in the treatment of sarcomas.
Journal: Targeted oncology 20110301
Title: [Effect of daunorubicin and rapamycin combination on the proliferation of acute leukemia cells].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110301
Title: Mechanisms of mTOR inhibitor resistance in cancer therapy.
Journal: Targeted oncology 20110301
Title: [Current status in molecular-targeted therapy and IFNα for renal cell carcinoma in Japan].
Journal: Hinyokika kiyo. Acta urologica Japonica 20110301
Title: [Determination of the content of zotarolimus on the drug eluting stents by HPLC].
Journal: Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation 20110301
Title: Resveratrol enhances the anti-tumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling.
Journal: Cancer letters 20110227
Title: Embryonic pig pancreatic tissue for the treatment of diabetes: potential role of immune suppression with 'off-the-shelf' third-party regulatory T cells.
Journal: Transplantation 20110227
Title: Inhibitory effects of the HDAC inhibitor valproic acid on prostate cancer growth are enhanced by simultaneous application of the mTOR inhibitor RAD001.
Journal: Life sciences 20110227
Title: mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells.
Journal: The Journal of biological chemistry 20110225
Title: A randomized clinical study comparing double kissing crush with provisional stenting for treatment of coronary bifurcation lesions: results from the DKCRUSH-II (Double Kissing Crush versus Provisional Stenting Technique for Treatment of Coronary Bifurcation Lesions) trial.
Journal: Journal of the American College of Cardiology 20110222
Title: mTOR inhibitor treatment of pancreatic cancer in a patient With Peutz-Jeghers syndrome.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110220
Title: Use of drug-eluting stents for chronic total occlusions: a systematic review and meta-analysis.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110215
Title: FOXO3a reactivation mediates the synergistic cytotoxic effects of rapamycin and cisplatin in oral squamous cell carcinoma cells.
Journal: Toxicology and applied pharmacology 20110215
Title: Combination mTOR and IGF-1R inhibition: phase I trial of everolimus and figitumumab in patients with advanced sarcomas and other solid tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110215
Title: Two-year safety and effectiveness of sirolimus-eluting stents (from a prospective registry).
Journal: The American journal of cardiology 20110215
Title: Temsirolimus, an mTOR inhibitor, enhances anti-tumour effects of heat shock protein cancer vaccines.
Journal: British journal of cancer 20110215
Title: Calcineurin inhibitor-free monotherapy in human leukocyte antigen–identical live donor renal transplantation.
Journal: Transplantation 20110215
Title: Perivascular sirolimus-delivery system.
Journal: International journal of pharmaceutics 20110214
Title: Everolimus for advanced pancreatic neuroendocrine tumors.
Journal: The New England journal of medicine 20110210
Title: Promising advances in the treatment of malignant pancreatic endocrine tumors.
Journal: The New England journal of medicine 20110210
Title: Everolimus and giant-cell astrocytomas in tuberous sclerosis.
Journal: The New England journal of medicine 20110210
Title: Everolimus and giant-cell astrocytomas in tuberous sclerosis.
Journal: The New England journal of medicine 20110210
Title: Spinal phosphinositide 3-kinase-Akt-mammalian target of rapamycin signaling cascades in inflammation-induced hyperalgesia.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110209
Title: Rapamycin suppresses mossy fiber sprouting but not seizure frequency in a mouse model of temporal lobe epilepsy.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110209
Title: Sirolimus eluting stent restenosis: impact of angiographic patterns and the treatment factors on angiographic outcomes in contemporary practice.
Journal: International journal of cardiology 20110203
Title: Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20110202
Title: Early graft dysfunction in a child with renal transplantation.
Journal: Pediatric nephrology (Berlin, Germany) 20110201
Title: mTOR partly mediates insulin resistance by phosphorylation of insulin receptor substrate-1 on serine(307) residues after burn.
Journal: Burns : journal of the International Society for Burn Injuries 20110201
Title: Integrating bevacizumab, everolimus, and lapatinib into current neoadjuvant chemotherapy regimen for primary breast cancer. Safety results of the GeparQuinto trial.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20110201
Title: The PI3K/Akt/mTOR pathway is activated in murine lupus nephritis and downregulated by rapamycin.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110201
Title: Comparison of sirolimus with azathioprine in a tacrolimus-based immunosuppressive regimen in lung transplantation.
Journal: American journal of respiratory and critical care medicine 20110201
Title: National Cancer Institute pediatric preclinical testing program: model description for in vitro cytotoxicity testing.
Journal: Pediatric blood & cancer 20110201
Title: Increased risk of venous thromboembolism with a sirolimus-based immunosuppression regimen in lung transplantation.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20110201
Title: Aging and TOR: interwoven in the fabric of life.
Journal: Cellular and molecular life sciences : CMLS 20110201
Title: Comparison of blood sirolimus, tacrolimus and everolimus concentrations measured by LC-MS/MS, HPLC-UV and immunoassay methods.
Journal: Clinical biochemistry 20110201
Title: Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20110201
Title: Beta cell function during rapamycin monotherapy in long-term type 1 diabetes.
Journal: Diabetologia 20110201
Title: Vertical inhibition of the mTORC1/mTORC2/PI3K pathway shows synergistic effects against melanoma in vitro and in vivo.
Journal: The Journal of investigative dermatology 20110201
Title: Antagonistic interactions between the cAMP-dependent protein kinase and Tor signaling pathways modulate cell growth in Saccharomyces cerevisiae.
Journal: Genetics 20110201
Title: A phase I study of bevacizumab (B) in combination with everolimus (E) and erlotinib (E) in advanced cancer (BEE).
Journal: Cancer chemotherapy and pharmacology 20110201
Title: Evidence for the involvement of mTOR inhibition and basal autophagy in familial Mediterranean fever phenotype.
Journal: Human immunology 20110201
Title: Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition.
Journal: Autophagy 20110201
Title: Dissecting the dynamic turnover of GFP-LC3 in the autolysosome.
Journal: Autophagy 20110201
Title: mTOR inhibitors and sorafenib for recurrent heptocellular carcinoma after orthotopic liver transplantation.
Journal: Journal of hepatology 20110201
Title: Rapamycin for treating Tuberous sclerosis and Autism spectrum disorders.
Journal: Trends in molecular medicine 20110201
Title: Combined targeting of the VEGFr/EGFr and the mammalian target of rapamycin (mTOR) signaling pathway delays cell cycle progression and alters adhesion behavior of prostate carcinoma cells.
Journal: Cancer letters 20110201
Title: A comparative assessment by optical coherence tomography of the performance of the first and second generation of the everolimus-eluting bioresorbable vascular scaffolds.
Journal: European heart journal 20110201
Title: Autophagy aids membrane expansion by neuropathic Schwann cells.
Journal: Autophagy 20110201
Title: A phase II trial of the oral mTOR inhibitor everolimus in relapsed aggressive lymphoma.
Journal: Leukemia 20110201
Title: Clinical safety and efficacy of everolimus-eluting stents compared to paclitaxel-eluting stents in patients with coronary artery disease.
Journal: Annals of medicine 20110201
Title: Loss of canonical insulin signaling accelerates vascular smooth muscle cell proliferation and migration through changes in p27Kip1 regulation.
Journal: Endocrinology 20110201
Title: Systemic influence of immunosuppressive drugs on small and large bowel transport and barrier function.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20110201
Title: Interpreting mammalian target of rapamycin and cell growth inhibition in a genetically engineered mouse model of Nf1-deficient astrocytes.
Journal: Molecular cancer therapeutics 20110201
Title: Influence of age on the clinical outcomes of coronary revascularisation for the treatment of patients with multivessel de novo coronary artery lesions: sirolimus-eluting stent vs. coronary artery bypass surgery and bare metal stent, insight from the multicentre randomised Arterial Revascularisation Therapy Study Part I (ARTS-I) and Part II (ARTS-II).
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110201
Title: Infected coronary artery pseudoaneurysm after repeated percutaneous coronary intervention.
Journal: The Annals of thoracic surgery 20110201
Title: Protein synthesis in plasma cells is regulated by crosstalk between endoplasmic reticulum stress and mTOR signaling.
Journal: European journal of immunology 20110201
Title: The mTOR inhibitor rapamycin suppresses DNA double-strand break repair.
Journal: Radiation research 20110201
Title: Randomized comparison of percutaneous coronary intervention with sirolimus-eluting stents versus coronary artery bypass grafting in unprotected left main stem stenosis.
Journal: Journal of the American College of Cardiology 20110201
Title: Total recall of radiotherapy with mTOR inhibitors: a novel and potentially frequent side-effect?
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20110201
Title: Very late thrombosis of sirolimus-eluting stent despite dual antiplatelet therapy for 4 years in a patient with lung cancer.
Journal: Minerva cardioangiologica 20110201
Title: Tailoring immunosuppressive therapy for lung transplantation: moving beyond hand-me-down data.
Journal: American journal of respiratory and critical care medicine 20110201
Title: Procedural and clinical evaluation of the novel zotarolimus-eluting resolute stent in patients with unselected bifurcated coronary stenosis treated by provisional approach: a multicenter registry.
Journal: The Journal of invasive cardiology 20110201
Title: Resolute™ drug-eluting stent: a resolution for bifurcation lesions?
Journal: The Journal of invasive cardiology 20110201
Title: Primary everolimus-eluting stenting versus balloon angioplasty with bailout bare metal stenting of long infrapopliteal lesions for treatment of critical limb ischemia.
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20110201
Title: Targeted therapies for the treatment of metastatic renal cell carcinoma: clinical evidence.
Journal: The oncologist 20110201
Title: Beyond traditional outcomes: improving quality of life in patients with renal cell carcinoma.
Journal: The oncologist 20110201
Title: Treatment-associated adverse event management in the advanced renal cell carcinoma patient treated with targeted therapies.
Journal: The oncologist 20110201
Title: Effectiveness of paclitaxel-eluting balloon catheter in patients with sirolimus-eluting stent restenosis.
Journal: JACC. Cardiovascular interventions 20110201
Title: The SPIRIT V study: a clinical evaluation of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with de novo coronary artery lesions.
Journal: JACC. Cardiovascular interventions 20110201
Title: Signaling to the ribosome in cancer--It is more than just mTORC1.
Journal: IUBMB life 20110201
Title: [Types and characteristic features of drug-eluting stents].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20110201
Title: Ten-month laryngeal allograft survival with use of pulsed everolimus and anti-alphabeta T-cell receptor antibody immunosuppression.
Journal: The Annals of otology, rhinology, and laryngology 20110201
Title: Conversion from cyclosporine to sirolimus in chronic renal allograft dysfunction: a 4-year prospective study.
Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20110201
Title: Immunosuppressive therapy in children.
Journal: Journal of the Indian Medical Association 20110201
Title: Rapamycin treatment causes developmental delay, pigmentation defects, and gastrointestinal malformation on Xenopus embryogenesis.
Journal: Biochemical and biophysical research communications 20110128
Title: Allospecific regulatory effects of sirolimus and tacrolimus in the human mixed lymphocyte reaction.
Journal: Transplantation 20110127
Title: Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP.
Journal: Journal of the American Chemical Society 20110126
Title: Coronary responses and differential mechanisms of late stent thrombosis attributed to first-generation sirolimus- and paclitaxel-eluting stents.
Journal: Journal of the American College of Cardiology 20110125
Title: Sirolimus- versus paclitaxel-eluting stents in patients with acute myocardial infarction: a meta-analysis of randomized trials.
Journal: International journal of cardiology 20110121
Title: Randomized study on provisional stenting with sirolimus-eluting stent vs. bare metal stent for the treatment of true coronary bifurcations: the PROSUMER (PROvisional with sirolimus-eluting vs. bare metal stents in truE bifuRcations) study.
Journal: International journal of cardiology 20110121
Title: Translation of 5' terminal oligopyrimidine tract (5'TOP) mRNAs in Aplysia Californica is regulated by the target of rapamycin (TOR).
Journal: Biochemical and biophysical research communications 20110121
Title: mTOR inhibitors and autosomal dominant polycystic kidney disease.
Journal: The New England journal of medicine 20110120
Title: mTOR inhibitors and autosomal dominant polycystic kidney disease.
Journal: The New England journal of medicine 20110120
Title: mTOR inhibitors and autosomal dominant polycystic kidney disease.
Journal: The New England journal of medicine 20110120
Title: Protective effect of immunosuppressive treatment before orthotopic kidney autotransplantation.
Journal: Transplant immunology 20110115
Title: Adoptive transfer of DNT cells induces long-term cardiac allograft survival and augments recipient CD4(+)Foxp3(+) Treg cell accumulation.
Journal: Transplant immunology 20110115
Title: Haplotypic arrangement in CYP3A locus is associated with side effects of proliferative signal inhibitors in renal transplant recipients.
Journal: Transplantation 20110115
Title: Mean glomerular volume after renal transplantation in patients receiving sirolimus and cyclosporine a compared with elimination of cyclosporine a at 3 months.
Journal: Transplantation 20110115
Title: Switching to sirolimus-based immune suppression after liver transplantation is safe and effective: a single-center experience.
Journal: Transplantation 20110115
Title: Multi-timescale dynamics study of FKBP12 along the rapamycin-mTOR binding coordinate.
Journal: Journal of molecular biology 20110114
Title: Inhibition of the mammalian target of rapamycin pathway by rapamycin blocks cocaine-induced locomotor sensitization.
Journal: Neuroscience 20110113
Title: Pipecolic acid derivatives as small-molecule inhibitors of the Legionella MIP protein.
Journal: Journal of medicinal chemistry 20110113
Title: A photocleavable rapamycin conjugate for spatiotemporal control of small GTPase activity.
Journal: Journal of the American Chemical Society 20110112
Title: Identification of FUSE-binding protein 1 as a regulatory mRNA-binding protein that represses nucleophosmin translation.
Journal: Oncogene 20110106
Title: α-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways.
Journal: British journal of cancer 20110104
Title: mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice.
Journal: The Journal of clinical investigation 20110104
Title: Coronary angiography and computed tomography angiography in the diagnosis of extrinsic compression of left internal mammary artery.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20110101
Title: The role of CYP3A5 genotypes in dose requirements of tacrolimus and everolimus after heart transplantation.
Journal: Clinical transplantation 20110101
Title: Inhibitors of phosphatidylinositol 3-kinase and mTOR but not Akt enhance replication of bovine ephemeral fever virus.
Journal: Veterinary journal (London, England : 1997) 20110101
Title: Randomized, double-blind, placebo-controlled, single intravenous dose-escalation study to evaluate the safety, tolerability, and pharmacokinetics of the novel coronary smooth muscle cell proliferation inhibitor Biolimus A9 in healthy individuals.
Journal: Journal of clinical pharmacology 20110101
Title: Inhibition of bladder tumour growth by sirolimus in an experimental carcinogenesis model.
Journal: BJU international 20110101
Title: Impressive response to temsirolimus in a patient with chemotherapy refractory diffuse large B-cell non-Hodgkin's lymphoma.
Journal: Annals of hematology 20110101
Title: Steroid minimization for sirolimus-treated renal transplant recipients.
Journal: Clinical transplantation 20110101
Title: First nine-month complete invasive assessment (angiography, IVUS, and OCT) of the novel NEVO sirolimus-eluting stent with biodegradable polymer.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101
Title: Sirolimus versus paclitaxel coronary stents in clinical practice.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101
Title: Everolimus and PTK/ZK show synergistic growth inhibition in the orthotopic BL16/BL6 murine melanoma model.
Journal: Cancer chemotherapy and pharmacology 20110101
Title: Temsirolimus in VEGF-refractory metastatic renal cell carcinoma.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20110101
Title: Inhibition of mTOR with sirolimus does not attenuate progression of liver and kidney disease in PCK rats.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110101
Title: Calcineurin inhibitor sparing regimens using m-target of rapamycin inhibitors: an opportunity to improve cardiovascular risk following kidney transplantation?
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20110101
Title: Regression of subependymal giant cell astrocytomas with RAD001 (Everolimus) in tuberous sclerosis complex.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20110101
Title: Activation of mTOR and RhoA is a major mechanism by which Ceramide 1-phosphate stimulates macrophage proliferation.
Journal: Cellular signalling 20110101
Title: Mammalian target of rapamycin (mTOR) phosphorylates inositol 1,4,5-trisphosphate receptor type 2 and increases its Ca(2+) release activity.
Journal: Cellular signalling 20110101
Title: Select nutrients in the ovine uterine lumen. VII. Effects of arginine, leucine, glutamine, and glucose on trophectoderm cell signaling, proliferation, and migration.
Journal: Biology of reproduction 20110101
Title: Differential modulation of the cytokine-induced MMP-9/TIMP-1 protease-antiprotease system by the mTOR inhibitor rapamycin.
Journal: Biochemical pharmacology 20110101
Title: Vitamin K3 attenuates cerulein-induced acute pancreatitis through inhibition of the autophagic pathway.
Journal: Pancreas 20110101
Title: Evaluation of the mTOR inhibitor, everolimus, in combination with cytotoxic antitumor agents using human tumor models in vitro and in vivo.
Journal: Anti-cancer drugs 20110101
Title: Angiographic and intravascular ultrasound follow up of paclitaxel- and sirolimus-eluting stent after poststent high-pressure balloon dilation: from the poststent optimal stent expansion trial.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101
Title: Oral sirolimus after bare metal stent implantation: a glimpse to the future.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101
Title: Activation of STAT1 is required for interferon-alpha-mediated cell death.
Journal: Experimental cell research 20110101
Title: mTORC1/2 and rapamycin in female Han:SPRD rats with polycystic kidney disease.
Journal: American journal of physiology. Renal physiology 20110101
Title: Enhanced sensitivity to rapamycin following long-term oestrogen deprivation in MCF-7, T-47-D and ZR-75-1 human breast cancer cells.
Journal: The Journal of endocrinology 20110101
Title: The mammalian target of rapamycin inhibitor RAD001 (everolimus) synergizes with chemotherapeutic agents, ionizing radiation and proteasome inhibitors in pre-B acute lymphocytic leukemia.
Journal: Haematologica 20110101
Title: Sirolimus damages podocytes in rats with protein overload nephropathy.
Journal: Journal of nephrology 20110101
Title: Phase III trial of everolimus in metastatic renal cell carcinoma: subgroup analysis of Japanese patients from RECORD-1.
Journal: Japanese journal of clinical oncology 20110101
Title: Identification of clinically used drugs that activate pregnane X receptors.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110101
Title: Long-term outcome of sirolimus-eluting stent implantation for left main coronary artery stenosis in infancy.
Journal: Pediatric cardiology 20110101
Title: Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase.
Journal: Autophagy 20110101
Title: Deciphering the signaling pathways of cancer stem cells of glioblastoma multiforme: role of Akt/mTOR and MAPK pathways.
Journal: Advances in enzyme regulation 20110101
Title: Partial graft recovery following eradication of hepatitis E virus infection after successful islet allograft transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20110101
Title: Assessment by optical coherence tomography of stent struts across side branch. -Comparison of bare-metal stents and drug-elution stents.-.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: Age and sex differences in the effects of the immunosuppressants cyclosporine, sirolimus and everolimus on rat brain metabolism.
Journal: Neurotoxicology 20110101
Title: Albuminuria after renal transplantation: maintenance with sirolimus/low-dose tacrolimus vs. mycophenolate mofetil/high-dose tacrolimus.
Journal: Clinical transplantation 20110101
Title: Drug-eluting stents for the treatment of pulmonary vein stenosis after atrial fibrillation ablation.
Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110101
Title: Impact of cytochrome P450 2C19*2 polymorphism on intra-stent thrombus after drug-eluting stent implantation in Japanese patients receiving clopidogrel.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: Predictors of stent fracture in patients treated with closed-cell design stents: sirolimus-eluting stent and its bare-metal counterpart, the BX velocity stent.
Journal: Coronary artery disease 20110101
Title: Phase I trial of oral mTOR inhibitor everolimus in combination with trastuzumab and vinorelbine in pre-treated patients with HER2-overexpressing metastatic breast cancer.
Journal: Breast cancer research and treatment 20110101
Title: Rapamycin inhibits lipopolysaccharide induction of granulocyte-colony stimulating factor and inducible nitric oxide synthase expression in macrophages by reducing the levels of octamer-binding factor-2.
Journal: The FEBS journal 20110101
Title: Immunosuppression with belatacept-based, corticosteroid-avoiding regimens in de novo kidney transplant recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110101
Title: The relationship between late lumen loss and restenosis among various drug-eluting stents: a systematic review and meta-regression analysis of randomized clinical trials.
Journal: Atherosclerosis 20110101
Title: Mechanisms mediating the cardioprotective effects of rapamycin in ischaemia-reperfusion injury.
Journal: Clinical and experimental pharmacology & physiology 20110101
Title: Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway.
Journal: The FEBS journal 20110101
Title: AP-1 regulates cyclin D1 and c-MYC transcription in an AKT-dependent manner in response to mTOR inhibition: role of AIP4/Itch-mediated JUNB degradation.
Journal: Molecular cancer research : MCR 20110101
Title: Evaluation of the novel protein kinase C inhibitor sotrastaurin as immunosuppressive therapy after renal transplantation.
Journal: Expert opinion on drug metabolism & toxicology 20110101
Title: Retrospective comparison of clinical and angiographic outcomes after primary stenting using sirolimus-eluting and bare-metal stents in nonrandomized consecutive 568 patients with first ST-segment elevated myocardial infarctions.
Journal: Journal of cardiology 20110101
Title: Tolerability of everolimus-based immunosuppression in maintenance liver transplant recipients.
Journal: Clinical transplantation 20110101
Title: Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology.
Journal: European journal of heart failure 20110101
Title: Control of carcinoid syndrome with everolimus.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20110101
Title: Clinical and angiographic outcomes with sirolimus-eluting stent for coronary bifurcation lesions. The J-PMS study.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: Drug-eluting stents vs. bare metal stents in saphenous vein graft disease. Insights from a meta-analysis of 7,090 patients.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: Neointimal coverage over coronary stent struts crossing the side branch Ostia.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: Prolonged survival in renal transplant recipient with advanced renal cell carcinoma by everolimus and sorafenib.
Journal: Nephrology (Carlton, Vic.) 20110101
Title: Everolimus: a new mammalian target of rapamycin inhibitor for the treatment of advanced renal cell carcinoma.
Journal: The Annals of pharmacotherapy 20110101
Title: Sirolimus- versus paclitaxel-eluting stents for unselected patients with coronary artery disease.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101
Title: Nevo stent: a successful stent makeover.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101
Title: Tuberous sclerosis complex: tumors and tumorigenesis.
Journal: International journal of dermatology 20110101
Title: Protein kinase B/Akt regulation in diabetic kidney disease.
Journal: Frontiers in bioscience (Scholar edition) 20110101
Title: Drug interaction between rifampicin and sirolimus in transplant patients.
Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20110101
Title: Medical management of skin disease: recent advances and future directions.
Journal: Journal of drugs in dermatology : JDD 20110101
Title: Sirolimus-eluting stent implantation versus beta-irradiation for the treatment of in-stent restenotic lesions: clinical and ultrasound results from a randomised trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110101
Title: Drug eluting stents for the treatment of bare metal in-stent restenosis: long-term outcomes in real world practice.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110101
Title: Clinical usefulness of drug-eluting stents in the treatment of dialysis patients with coronary artery disease.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110101
Title: The mTOR kinase inhibitor rapamycin decreases iNOS mRNA stability in astrocytes.
Journal: Journal of neuroinflammation 20110101
Title: Clinical characteristics of coronary drug-eluting stent fracture: insights from a two-center des registry.
Journal: Journal of Korean medical science 20110101
Title: Therapeutic targeting the loss of the birt-hogg-dube suppressor gene.
Journal: Molecular cancer therapeutics 20110101
Title: Targeting the PI3K/mTOR pathway in murine endocrine cell lines: in vitro and in vivo effects on tumor cell growth.
Journal: The American journal of pathology 20110101
Title: Conditional depletion of nuclear proteins by the Anchor Away system.
Journal: Current protocols in molecular biology 20110101
Title: The final answer? For the treatment of saphenous vein graft disease, drug-eluting stents vs. bare-metal stents.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: Two-dose-level confirmatory study of the pharmacokinetics and tolerability of everolimus in Chinese patients with advanced solid tumors.
Journal: Journal of hematology & oncology 20110101
Title: Two-year outcome of Turkish patients treated with Zotarolimus versus Paclitaxel eluting stents in an unselected population with coronary artery disease in the real world: a prospective non-randomized registry in southern Turkey.
Journal: International journal of medical sciences 20110101
Title: Selective inhibition of cyclooxygenase-2 suppresses metastatic disease without affecting primary tumor growth in a murine model of Ewing sarcoma.
Journal: Journal of pediatric surgery 20110101
Title: Good outcomes with cyclosporine very low exposure with everolimus high exposure in renal transplant patients.
Journal: Journal of nephrology 20110101
Title: Late stent thrombosis secondary to carbon monoxide poisoning.
Journal: Cardiovascular revascularization medicine : including molecular interventions 20110101
Title: Everolimus resolving hypoglycemia, producing hyperglycemia, and necessitating insulin use in a patient with diabetes and nonresectable malignant insulinoma.
Journal: Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20110101
Title: Four-year follow-up of TYPHOON (trial to assess the use of the CYPHer sirolimus-eluting coronary stent in acute myocardial infarction treated with BallOON angioplasty).
Journal: JACC. Cardiovascular interventions 20110101
Title: Very late stent thrombosis after primary percutaneous coronary intervention with bare-metal and drug-eluting stents for ST-segment elevation myocardial infarction: a 15-year single-center experience.
Journal: JACC. Cardiovascular interventions 20110101
Title: Long-term follow-up of drug-eluting stents placed in the setting of ST-segment elevation myocardial infarction.
Journal: JACC. Cardiovascular interventions 20110101
Title: Persistent coronary no flow after wire insertion is an early and readily available mortality risk factor despite successful mechanical intervention in acute myocardial infarction: a pooled analysis from the STRATEGY (Single High-Dose Bolus Tirofiban and Sirolimus-Eluting Stent Versus Abciximab and Bare-Metal Stent in Acute Myocardial Infarction) and MULTISTRATEGY (Multicenter Evaluation of Single High-Dose Bolus Tirofiban Versus Abciximab With Sirolimus-Eluting Stent or Bare-Metal Stent in Acute Myocardial
Journal: JACC. Cardiovascular interventions 20110101
Title: Prediction of 1-year clinical outcomes using the SYNTAX score in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a substudy of the STRATEGY (Single High-Dose Bolus Tirofiban and Sirolimus-Eluting Stent Versus Abciximab and Bare-Metal Stent in Acute Myocardial Infarction) and MULTISTRATEGY (Multicenter Evaluation of Single High-Dose Bolus Tirofiban Versus Abciximab With Sirolimus-Eluting Stent or Bare-Metal Stent in Acute Myocardial Infarc
Journal: JACC. Cardiovascular interventions 20110101
Title: Late restenosis following sirolimus-eluting stent implantation.
Journal: JACC. Cardiovascular interventions 20110101
Title: Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells.
Journal: PloS one 20110101
Title: The impact of sirolimus on hepatitis C recurrence after liver transplantation.
Journal: Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20110101
Title: Rapamycin blocks production of KSHV/HHV8: insights into the anti-tumor activity of an immunosuppressant drug.
Journal: PloS one 20110101
Title: Initial experience with temsirolimus in 2nd-, 3rd- and 4th-line therapy for metastatic renal cell cancer: good clinical response.
Journal: Urologia internationalis 20110101
Title: Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma.
Journal: PloS one 20110101
Title: Clinical evidence on the use of anti-mTOR drugs in renal transplantation.
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101
Title: Temsirolimus in metastatic chromophobe renal cell carcinoma after interferon and sorafenib therapy.
Journal: Anticancer research 20110101
Title: Response to mTOR inhibition: activity of eIF4E predicts sensitivity in cell lines and acquired changes in eIF4E regulation in breast cancer.
Journal: Molecular cancer 20110101
Title: The incidence of cancer and potential role of sirolimus immunosuppression conversion on mortality among a single-center renal transplantation cohort of 1,816 patients.
Journal: Transplantation proceedings 20110101
Title: Sirolimus prevents short-term renal changes induced by ischemia-reperfusion injury in rats.
Journal: American journal of nephrology 20110101
Title: Retrospective analyses of patient characteristics having predictive impact on survival under everolimus.
Journal: Onkologie 20110101
Title: Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer.
Journal: Breast cancer research : BCR 20110101
Title: The clinical evaluation of the Endeavor zotarolimus-eluting coronary stent in Japanese patients with de novo native coronary artery lesions: primary results and 3-year follow-up of the Endeavor Japan study.
Journal: Cardiovascular revascularization medicine : including molecular interventions 20110101
Title: Late regression of Cypher in-stent restenosis.
Journal: Cardiovascular revascularization medicine : including molecular interventions 20110101
Title: [Immunosuppressive agents in kidney transplantation].
Journal: Nihon Jinzo Gakkai shi 20110101
Title: [Autosomal dominant polycystic kidney disease].
Journal: Nihon Jinzo Gakkai shi 20110101
Title: Efficacy of paclitaxel-eluting stent in patients with impaired glucose tolerance--comparison with sirolimus-eluting stent.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: Candesartan with pioglitazone protects against endothelial dysfunction and inflammatory responses in porcine coronary arteries implanted with sirolimus-eluting stents.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: Angioscopic assessment of arterial repair following biodegradable polymer-coated biolimus A9-eluting stent implantation. - Comparison with durable polymer-coated sirolimus-eluting stent-.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: Rapamycin potentiates cytotoxicity by docetaxel possibly through downregulation of Survivin in lung cancer cells.
Journal: Journal of experimental & clinical cancer research : CR 20110101
Title: Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis.
Journal: Nature communications 20110101
Title: Inverse probability weighting to control for censoring in a post hoc analysis of quality-adjusted survival data from a clinical trial of temsirolimus for renal cell carcinoma.
Journal: Journal of medical economics 20110101
Title: Conversion from sirolimus to everolimus in kidney transplant recipients receiving a calcineurin-free regimen.
Journal: Clinical transplantation 20110101
Title: Targeting FK506 binding proteins to fight malarial and bacterial infections: current advances and future perspectives.
Journal: Current medicinal chemistry 20110101
Title: Combined therapeutic strategy to improve vascular endothelial function after implantation of sirolimus-eluting stents.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: Protective role of autophagy in AGE-induced early injury of human vascular endothelial cells.
Journal: Molecular medicine reports 20110101
Title: Regression of Kaposi's sarcoma in a Sudanese kidney transplant recipient after conversion to sirolimus: a focus on a common clinical problem.
Journal: Arab journal of nephrology and transplantation 20110101
Title: The impact of new generation drug-eluting stent implantation on patients with chronic kidney disease and a single lesion in the proximal segment of the left anterior descending artery.
Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20110101
Title: Tuberous sclerosis complex-1 deficiency attenuates diet-induced hepatic lipid accumulation.
Journal: PloS one 20110101
Title: Retrospective comparison of clinical and angiographic outcomes after sirolimus-eluting and bare-metal stent implantation in 312 consecutive, nonrandomized severely calcified lesions using a rotablator.
Journal: International heart journal 20110101
Title: Switching to sirolimus monotherapy for de novo tumors after liver transplantation. A preliminary experience.
Journal: Hepato-gastroenterology 20110101
Title: Amino acid signaling in TOR activation.
Journal: Annual review of biochemistry 20110101
Title: Host-based Th2 cell therapy for prolongation of cardiac allograft viability.
Journal: PloS one 20110101
Title: Rapid estimation of whole blood everolimus concentrations using architect sirolimus immunoassay and mathematical equations: comparison with everolimus values determined by liquid chromatography/mass spectrometry.
Journal: Journal of clinical laboratory analysis 20110101
Title: Rapamycin-loaded nanoparticles for inhibition of neointimal hyperplasia in experimental vein grafts.
Journal: Journal of cardiothoracic surgery 20110101
Title: Antigen-independent IFN-γ production by human naïve CD4 T cells activated by IL-12 plus IL-18.
Journal: PloS one 20110101
Title: Rapamycin-induced impaired wound healing is associated with compromised tissue lactate accumulation and extracellular matrix remodeling.
Journal: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20110101
Title: Sex difference in long-term clinical outcome after sirolimus-eluting stent implantation.
Journal: Coronary artery disease 20110101
Title: [Breast cancer therapy with combination of endocrine and target drugs].
Journal: Voprosy onkologii 20110101
Title: Is sirolimus a therapeutic option for patients with progressive pulmonary lymphangioleiomyomatosis?
Journal: Respiratory research 20110101
Title: Immunosuppressant cytoprotection correlates with HMGB1 suppression in primary astrocyte cultures exposed to combined oxygen-glucose deprivation.
Journal: Pharmacological reports : PR 20110101
Title: Efficacy of temsirolimus after previous treatment with sunitinib, sorafenib or everolimus in advanced renal cell cancer.
Journal: Oncology 20110101
Title: Rapamycin ameliorates dystrophic phenotype in mdx mouse skeletal muscle.
Journal: Molecular medicine (Cambridge, Mass.) 20110101
Title: Characterization of the metabolic phenotype of rapamycin-treated CD8+ T cells with augmented ability to generate long-lasting memory cells.
Journal: PloS one 20110101
Title: Drug-eluting stent: importance of clinico-pathological correlations.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: [Changes of content of regulatory lymphocytes and concentration of soluble interleukine-2 receptor in blood of patients with ischemic heart disease after coronary artery angioplasty with implantation of stents with rapamycin covering].
Journal: Kardiologiia 20110101
Title: Morphological and quantitative analysis of vascular wall and neointimal hyperplasia after coronary stenting: comparison of bare-metal and sirolimus-eluting stents using optical coherence tomography.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: Origin of restenosis after drug-eluting stent implantation in hyperglycemia is inflammatory cells and thrombus.
Journal: Journal of atherosclerosis and thrombosis 20110101
Title: The role of mTOR inhibitors in renal diseases.
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101
Title: Effects of rapamycin on angiomyolipomas in patients with tuberous sclerosis.
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101
Title: Monitoring sirolimus levels: how does it affect the immunoassay used?
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101
Title: Revascularization of left main coronary artery disease.
Journal: Cardiology in review 20110101
Title: Estimating the threshold surface density of Gp120-CCR5 complexes necessary for HIV-1 envelope-mediated cell-cell fusion.
Journal: PloS one 20110101
Title: Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in cancer stem cells.
Journal: Current medicinal chemistry 20110101
Title: Targeting mTOR signaling pathway in ovarian cancer.
Journal: Current medicinal chemistry 20110101
Title: Comparative study of clinical grade human tolerogenic dendritic cells.
Journal: Journal of translational medicine 20110101
Title: Sirolimus may be associated with early recurrence of biliary obstruction in liver transplant patients undergoing endoscopic stenting of biliary strictures.
Journal: Annals of hepatology 20110101
Title: Effects of cyclosporine, tacrolimus and rapamycin on renal calcium transport and vitamin D metabolism.
Journal: American journal of nephrology 20110101
Title: The combination of RAD001 and NVP-BEZ235 exerts synergistic anticancer activity against non-small cell lung cancer in vitro and in vivo.
Journal: PloS one 20110101
Title: Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN.
Journal: PloS one 20110101
Title: Rapamycin-based inducible translocation systems for studying phagocytosis.
Journal: Methods in molecular biology (Clifton, N.J.) 20110101
Title: Calcineurin inhibitor-based and free regimens have distinct gene expression patterns in subclinical graft fibrosis.
Journal: Annals of transplantation 20110101
Title: Collapsing glomerulopathy in a renal transplant recipient: potential molecular mechanisms.
Journal: Annals of transplantation 20110101
Title: [Rapamycin effect on senescence and autophagy processes in human cell lines].
Journal: Medicina 20110101
Title: mTOR controls ovarian follicle growth by regulating granulosa cell proliferation.
Journal: PloS one 20110101
Title: Determination of blood everolimus concentrations in kidney and liver transplant recipients using the sirolimus antibody conjugated magnetic immunoassay (ACMIA).
Journal: Clinical laboratory 20110101
Title: Comparison of paclitaxel-, sirolimus-, and zotarolimus-eluting stents in patients with acute ST-segment elevation myocardial infarction and metabolic syndrome.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: Impact of acute gain on clinical outcomes of patients treated with sirolimus-eluting stent. - A sub-analysis study from the STLLR trial-.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: Very late sirolimus-eluting stent thrombosis due to stent fracture and late-acquired incomplete stent apposition detected on multislice computed tomography.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101
Title: Direct microscopic observation of striations in a fractured section of a sirolimus-eluting stent (Cypher Bx Velocity®) indicates induction of stent fracture by continuous shear stress.
Journal: International heart journal 20110101
Title: Rapamycin inhibits the proliferation and apoptosis of gastric cancer cells by down regulating the expression of survivin.
Journal: Hepato-gastroenterology 20110101
Title: Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer.
Journal: Journal of translational medicine 20110101
Title: A periadventitial sirolimus-releasing mesh decreased intimal hyperplasia in a rabbit model.
Journal: Physiological research 20110101
Title: Involvement of mTOR signaling in sphingosylphosphorylcholine-induced hypopigmentation effects.
Journal: Journal of biomedical science 20110101
Title: Evolution of glomerular filtration rate, renal injury markers, anemia, and angiotensin blockers use after change from calcineurin inhibitors to sirolimus in transplant patients with neoplasia versus chronic allograft nephropathy.
Journal: Transplantation proceedings 20110101
Title: Everolimus in clinical practice in long-term liver transplantation: an observational study.
Journal: Transplantation proceedings 20110101
Title: Effectiveness and safety of everolimus in the treatment of autoimmune hepatitis related to anti-hepatitis C virus therapy after liver transplant: three case reports.
Journal: Transplantation proceedings 20110101
Title: Conversion to everolimus in liver transplant patients with renal dysfunction.
Journal: Transplantation proceedings 20110101
Title: Long-term use of everolimus in lung transplant patients.
Journal: Transplantation proceedings 20110101
Title: Cutaneous and mucosal aphthosis during temsirolimus therapy for advanced renal cell carcinoma: review of cutaneous and mucosal side effects of mTOR inhibitors.
Journal: Dermatology (Basel, Switzerland) 20110101
Title: SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition.
Journal: PloS one 20110101
Title: Endothelial-like cells in chronic thromboembolic pulmonary hypertension: crosstalk with myofibroblast-like cells.
Journal: Respiratory research 20110101
Title: Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis.
Journal: BMC cancer 20110101
Title: [Mass spectrometry-based quantitative analysis and biomarker discovery].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101
Title: Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1.
Journal: PloS one 20110101
Title: Calcineurin inhibitor-induced and Ras-mediated overexpression of VEGF in renal cancer cells involves mTOR through the regulation of PRAS40.
Journal: PloS one 20110101
Title: The peptidyl prolyl isomerase Rrd1 regulates the elongation of RNA polymerase II during transcriptional stresses.
Journal: PloS one 20110101
Title: Inhibition of radiation induced migration of human head and neck squamous cell carcinoma cells by blocking of EGF receptor pathways.
Journal: BMC cancer 20110101
Title: c-Myc dependent expression of pro-apoptotic Bim renders HER2-overexpressing breast cancer cells dependent on anti-apoptotic Mcl-1.
Journal: Molecular cancer 20110101
Title: Chikungunya triggers an autophagic process which promotes viral replication.
Journal: Virology journal 20110101
Title: Molecular mechanisms of l-DOPA-induced dyskinesia.
Journal: International review of neurobiology 20110101
Title: Economic evaluation of everolimus versus sorafenib for the treatment of metastatic renal cell carcinoma after failure of first-line sunitinib.
Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20110101
Title: Multicenter phase 2 trial of sirolimus for tuberous sclerosis: kidney angiomyolipomas and other tumors regress and VEGF- D levels decrease.
Journal: PloS one 20110101
Title: Involvement of mTOR in CXCL12 mediated T cell signaling and migration.
Journal: PloS one 20110101
Title: The activation of the p53 pathway by the AMP mimetic AICAR is reduced by inhibitors of the ATM or mTOR kinases.
Journal: Mechanisms of ageing and development 20110101
Title: Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells.
Journal: PloS one 20110101
Title: The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation.
Journal: Molecular systems biology 20110101
Title: Ezetimibe in sirolimus-associated hyperlipidemia: to add or not to add to statins?
Journal: Annals of transplantation 20110101
Title: The combination of gefitinib and RAD001 inhibits growth of HER2 overexpressing breast cancer cells and tumors irrespective of trastuzumab sensitivity.
Journal: BMC cancer 20110101
Title: Temporal regulation of rapamycin on memory CTL programming by IL-12.
Journal: PloS one 20110101
Title: Anti-proliferation effects of Sirolimus sustained delivery film in rabbit glaucoma filtration surgery.
Journal: Molecular vision 20110101
Title: Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits.
Journal: PloS one 20110101
Title: Human glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 mouse model of ALS.
Journal: PloS one 20110101
Title: Elimination of proliferating cells unmasks the shift from senescence to quiescence caused by rapamycin.
Journal: PloS one 20110101
Title: A mechanism for synergy with combined mTOR and PI3 kinase inhibitors.
Journal: PloS one 20110101
Title: Retrospective comparison of the clinical and angiographic outcomes of the sirolimus-eluting stent and the bare-metal stent in 2031 nonrandomized consecutive de novo native coronary lesions.
Journal: Internal medicine (Tokyo, Japan) 20110101
Title: Neoadjuvant chemotherapy and targeted therapies: a promising strategy.
Journal: Journal of the National Cancer Institute. Monographs 20110101
Title: Combined treatment with antioxidants and immunosuppressants on cytokine release by human peripheral blood mononuclear cells - chemically injured keratocyte reaction.
Journal: Molecular vision 20110101
Title: Mapping the interaction of Snf1 with TORC1 in Saccharomyces cerevisiae.
Journal: Molecular systems biology 20110101
Title: [Metastatic renal cell carcinoma treated with everolimus--data from the RENIS Clinical Registry].
Journal: Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20110101
Title: Targeting notch pathway enhances rapamycin antitumor activity in pancreas cancers through PTEN phosphorylation.
Journal: Molecular cancer 20110101
Title: Concurrent HDAC and mTORC1 inhibition attenuate androgen receptor and hypoxia signaling associated with alterations in microRNA expression.
Journal: PloS one 20110101
Title: Everolimus and long acting octreotide as a volume reducing treatment of polycystic livers (ELATE): study protocol for a randomized controlled trial.
Journal: Trials 20110101
Title: S6K1 and 4E-BP1 are independent regulated and control cellular growth in bladder cancer.
Journal: PloS one 20110101
Title: Giant bilateral renal angiomyolipomas and lymphangioleiomyomatosis presenting after two successive pregnancies successfully treated with surgery and rapamycin.
Journal: TheScientificWorldJournal 20110101
Title: Phase I-II study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell cancer.
Journal: BMC cancer 20110101
Title: Evaluation of an AAV2-based rapamycin-regulated glial cell line-derived neurotrophic factor (GDNF) expression vector system.
Journal: PloS one 20110101
Title: Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with paclitaxel infusion.
Journal: PloS one 20110101
Title: Transient mTOR inhibition facilitates continuous growth of liver tumors by modulating the maintenance of CD133+ cell populations.
Journal: PloS one 20110101
Title: Therapy for aplastic anemia.
Journal: Hematology. American Society of Hematology. Education Program 20110101
Title: Enhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent process.
Journal: International journal of nanomedicine 20110101
Title: Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation.
Journal: PloS one 20110101
Title: Two cases of everolimus-associated interstitial pneumonia in patients with renal cell carcinoma.
Journal: Internal medicine (Tokyo, Japan) 20110101
Title: Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway.
Journal: PloS one 20110101
Title: Progressive lymphangiomatosis and Gorham's disease: case report and clinical implications.
Journal: Lymphatic research and biology 20110101
Title: Pulmonary embolism and reactivation of tuberculosis during everolimus therapy in a kidney transplant recipient.
Journal: Annals of transplantation 20110101
Title: Sensitivity of global translation to mTOR inhibition in REN cells depends on the equilibrium between eIF4E and 4E-BP1.
Journal: PloS one 20110101
Title: Rapamycin prevents endothelial cell migration by inhibiting the endothelial-to-mesenchymal transition and matrix metalloproteinase-2 and -9: an in vitro study.
Journal: Molecular vision 20110101
Title: Procedure for determination of immunosuppressive drugs in whole blood with liquid chromatography-isotope dilution mass spectrometry.
Journal: Clinical laboratory 20110101
Title: Resveratrol inhibits protein translation in hepatic cells.
Journal: PloS one 20110101
Title: Compassionate use of everolimus in a patient with a neuroendocrine tumor: a case report and discussion of the literature.
Journal: Oncology research 20110101
Title: Combination effects of paclitaxel with signaling inhibitors in endometrial cancer cells.
Journal: Asian Pacific journal of cancer prevention : APJCP 20110101
Title: [Efficiency of medical versus endovascular treatment using drug-eluting stents in coronary heart disease patients with extensive lesion of the coronary bed].
Journal: Vestnik rentgenologii i radiologii 20110101
Title: [Post transplant lymphoproliferative disorder (PTLD)--10 years follow-up].
Journal: Przeglad lekarski 20110101
Title: Acute thrombosis of drug eluting stent following protamine: a case report.
Journal: Indian heart journal 20110101
Title: Two-year outcomes in thoracic transplant recipients after conversion to everolimus with reduced calcineurin inhibitor within a multicenter, open-label, randomized trial.
Journal: Transplantation 20101227
Title: The International Registry on Hand and Composite Tissue Transplantation.
Journal: Transplantation 20101227
Title: Anti-BK virus mechanisms of sirolimus and leflunomide alone and in combination: toward a new therapy for BK virus infection.
Journal: Transplantation 20101227
Title: Hsp90 and environmental stress transform the adaptive value of natural genetic variation.
Journal: Science (New York, N.Y.) 20101224
Title: Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways.
Journal: Blood 20101223
Title: RAD001 shows activity against gastric cancer cells and overcomes 5-FU resistance by downregulating thymidylate synthase.
Journal: Cancer letters 20101218
Title: Development of a dot-blot assay for screening monoclonal antibodies to low-molecular-mass drugs.
Journal: Analytical biochemistry 20101215
Title: Treatment of childhood kaposiform hemangioendothelioma with sirolimus.
Journal: Pediatric blood & cancer 20101215
Title: Temsirolimus for metastatic desmoplastic small round cell tumor.
Journal: Pediatric blood & cancer 20101215
Title: Immunosuppression involving soluble CD83 induces tolerogenic dendritic cells that prevent cardiac allograft rejection.
Journal: Transplantation 20101215
Title: Prolidase-dependent regulation of TGF β (corrected) and TGF β receptor expressions in human skin fibroblasts.
Journal: European journal of pharmacology 20101215
Title: Unequal in the absence of death: a novel screen identifies cytotoxic compounds selective for cells with activated Akt.
Journal: Cancer biology & therapy 20101215
Title: Identification of Akt-selective cytotoxic compounds that enhance cytotoxic responses to rapamycin.
Journal: Cancer biology & therapy 20101215
Title: Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process.
Journal: Cancer research 20101215
Title: Isolation and expansion of human natural T regulatory cells for cellular therapy.
Journal: Journal of immunological methods 20101215
Title: Mammalian target of rapamycin: biological function and target for novel anticancer agents.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101215
Title: Increasing healthy lifespan by suppressing aging in our lifetime: preliminary proposal.
Journal: Cell cycle (Georgetown, Tex.) 20101215
Title: Pemetrexed indirectly activates the metabolic kinase AMPK in human carcinomas.
Journal: Cancer research 20101215
Title: BRAF mutation-selective inhibition of thyroid cancer cells by the novel MEK inhibitor RDEA119 and genetic-potentiated synergism with the mTOR inhibitor temsirolimus.
Journal: International journal of cancer 20101215
Title: Outcomes in diabetic and nondiabetic patients treated with everolimus- or paclitaxel-eluting stents: results from the SPIRIT IV clinical trial (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System).
Journal: Journal of the American College of Cardiology 20101214
Title: An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness.
Journal: Immunity 20101214
Title: C60(Nd) nanoparticles enhance chemotherapeutic susceptibility of cancer cells by modulation of autophagy.
Journal: Nanotechnology 20101210
Title: GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28- CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression.
Journal: Blood 20101209
Title: Drug-eluting versus bare-metal stents in large coronary arteries.
Journal: The New England journal of medicine 20101209
Title: Combinations of mTORC1 inhibitor RAD001 with gemcitabine and paclitaxel for treating non-Hodgkin lymphoma.
Journal: Cancer letters 20101208
Title: Copper-doxorubicin as a nanoparticle cargo retains efficacy with minimal toxicity.
Journal: Molecular pharmaceutics 20101206
Title: Targeted drug delivery to lymphocytes: a route to site-specific immunomodulation?
Journal: Molecular pharmaceutics 20101206
Title: Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity.
Journal: The Journal of biological chemistry 20101203
Title: Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells.
Journal: Nature 20101202
Title: Reflex sympathetic dystrophy in patients with metastatic renal cell carcinoma treated with everolimus.
Journal: Investigational new drugs 20101201
Title: TAE226-mediated inhibition of focal adhesion kinase interferes with tumor angiogenesis and vasculogenesis.
Journal: Investigational new drugs 20101201
Title: Pharmacodynamic evaluation of temsirolimus in patients with newly diagnosed advanced-stage head and neck squamous cell carcinoma.
Journal: Head & neck 20101201
Title: Mammalian target of rapamycin signaling in the spinal cord is required for neuronal plasticity and behavioral hypersensitivity associated with neuropathy in the rat.
Journal: The journal of pain : official journal of the American Pain Society 20101201
Title: Intrinsic and extrinsic mechanisms of oocyte loss.
Journal: Molecular human reproduction 20101201
Title: Quantitative determination of sirolimus in dog blood using liquid chromatography-tandem mass spectrometry, and its applications to pharmacokinetic studies.
Journal: Journal of pharmaceutical and biomedical analysis 20101201
Title: A phase 2 study of the oral mammalian target of rapamycin inhibitor, everolimus, in patients with recurrent endometrial carcinoma.
Journal: Cancer 20101201
Title: TORC1 kinase and the S-phase cyclin Clb5 collaborate to promote mitotic spindle assembly and DNA replication in S. cerevisiae.
Journal: Current genetics 20101201
Title: Sirolimus for calcineurin inhibitors in organ transplantation: contra.
Journal: Kidney international 20101201
Title: Dysregulation of epithelial Na+ absorption induced by inhibition of the kinases TORC1 and TORC2.
Journal: British journal of pharmacology 20101201
Title: Autosomal dominant polycystic kidney disease and mTOR inhibitors: the narrow road between hope and disappointment.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101201
Title: Mammalian target of rapamycin inhibition abrogates insulin-mediated mammary tumor progression in type 2 diabetes.
Journal: Endocrine-related cancer 20101201
Title: Regulation of gastric hormones by systemic rapamycin.
Journal: Peptides 20101201
Title: Comparison of three-year clinical outcomes between sirolimus-versus paclitaxel-eluting stents in diabetic patients: prospective randomized multicenter trial.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101201
Title: Mammalian target of rapamycin signaling activation patterns in neuroendocrine tumors of the lung.
Journal: Endocrine-related cancer 20101201
Title: Silymarin inhibits endothelial progenitor cells' senescence and protects against the antiproliferative activity of rapamycin: preliminary study.
Journal: Journal of cardiovascular pharmacology 20101201
Title: Curcumin inhibits carcinogen and nicotine-induced Mammalian target of rapamycin pathway activation in head and neck squamous cell carcinoma.
Journal: Cancer prevention research (Philadelphia, Pa.) 20101201
Title: mTOR inhibitor rapamycin suppresses striatal post-ischemic LTP.
Journal: Experimental neurology 20101201
Title: Crush stenting with drug-eluting stents: relevance of coronary bifurcation lesion location on angiographic and clinical outcomes.
Journal: Clinical cardiology 20101201
Title: Dual blocking of mTor and PI3K elicits a prodifferentiation effect on glioblastoma stem-like cells.
Journal: Neuro-oncology 20101201
Title: The potential benefits of rapamycin on renal function, tolerance, fibrosis, and malignancy following transplantation.
Journal: Kidney international 20101201
Title: Rapamycin inhibits cell proliferation in type I and type II endometrial carcinomas: a search for biomarkers of sensitivity to treatment.
Journal: Gynecologic oncology 20101201
Title: Third-line sorafenib after sequential therapy with sunitinib and mTOR inhibitors in metastatic renal cell carcinoma.
Journal: European urology 20101201
Title: Inhibition of voltage-gated K+ channels in dendritic cells by rapamycin.
Journal: American journal of physiology. Cell physiology 20101201
Title: mTOR-inhibition in metastatic renal cell carcinoma. Focus on temsirolimus: a review.
Journal: Minerva urologica e nefrologica = The Italian journal of urology and nephrology 20101201
Title: Mechanical stretch activates signaling events for protein translation initiation and elongation in C2C12 myoblasts.
Journal: Molecules and cells 20101201
Title: Phase I study of everolimus plus weekly paclitaxel and trastuzumab in patients with metastatic breast cancer pretreated with trastuzumab.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101201
Title: Cellular and molecular changes associated with inhibitory effect of pioglitazone on neointimal growth in patients with type 2 diabetes after zotarolimus-eluting stent implantation.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20101201
Title: Determination of cyclosporine, tacrolimus, sirolimus and everolimus by liquid chromatography coupled to electrospray ionization and tandem mass spectrometry: assessment of matrix effects and assay performance.
Journal: Scandinavian journal of clinical and laboratory investigation 20101201
Title: mTORC1 inhibition via rapamycin promotes triacylglycerol lipolysis and release of free fatty acids in 3T3-L1 adipocytes.
Journal: Lipids 20101201
Title: Phase II study of everolimus (RAD001) in previously treated small cell lung cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20101201
Title: Six-month results of the NEVO Res-Elution I (NEVO RES-I) trial: a randomized, multicenter comparison of the NEVO sirolimus-eluting coronary stent with the TAXUS Liberté paclitaxel-eluting stent in de novo native coronary artery lesions.
Journal: Circulation. Cardiovascular interventions 20101201
Title: Lysosomal accumulation of mTOR is enhanced by rapamycin.
Journal: Histochemistry and cell biology 20101201
Title: Developmental pharmacogenetics of immunosuppressants in pediatric organ transplantation.
Journal: Therapeutic drug monitoring 20101201
Title: Development of a validated high-throughput LC-ESI-MS method for determination of sirolimus on dried blood spots.
Journal: Biomedical chromatography : BMC 20101201
Title: Protein kinase Mzeta is essential for the induction and maintenance of dopamine-induced long-term potentiation in apical CA1 dendrites.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20101201
Title: The Kounis syndrome in everolimus-eluting stents and paclitaxel-eluting stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101201
Title: Safety and efficacy of sirolimus-eluting stent implantation in patients with acute coronary syndrome in the real world.
Journal: The American journal of cardiology 20101201
Title: Effect of FKBP65, a putative elastin chaperone, on the coacervation of tropoelastin in vitro.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20101201
Title: High glycemic stenting menu.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101201
Title: Do mTOR inhibitors still have a future in ADPKD?
Journal: Nature reviews. Nephrology 20101201
Title: Sirolimus and kidney transplantation: unraveling an inflammatory affair.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101201
Title: Comparative transcriptional and phenotypic peripheral blood analysis of kidney recipients under cyclosporin A or sirolimus monotherapy.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101201
Title: Recurrent stent fracture: first reported image of everolimus-eluting stent fracture leading to recurrent restenosis in cardiac allograft vasculopathy.
Journal: The Journal of invasive cardiology 20101201
Title: Proteinuria among primarily sirolimus treated live-donor renal transplant recipients' long-term experience.
Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20101201
Title: Rapamycin inhibits anal carcinogenesis in two preclinical animal models.
Journal: Cancer prevention research (Philadelphia, Pa.) 20101201
Title: mTOR and its link to the picture of Dorian Gray - re-activation of mTOR promotes aging.
Journal: Aging 20101201
Title: Intracellular amino acid sensing and mTORC1-regulated growth: new ways to block an old target?
Journal: Current opinion in investigational drugs (London, England : 2000) 20101201
Title: Long-term outcome of very early cyclosporine minimization and de novo everolimus therapy in kidney transplant recipients: a pharmacokinetic guided approach.
Journal: Transplantation proceedings 20101201
Title: Conversion from calcineurin inhibitor to either mycophenolate mofetil or sirolimus improves renal function in liver transplant recipients with chronic kidney disease: results of a prospective randomized trial.
Journal: Transplantation proceedings 20101201
Title: Individualizing early use of sirolimus in renal transplantation.
Journal: Transplantation proceedings 20101201
Title: Potential use of rapamycin in HIV infection.
Journal: British journal of clinical pharmacology 20101201
Title: Unilateral upper limb lympatic obstruction and severe lymphoedema in a patient on long-term sirolimus.
Journal: Nephrology (Carlton, Vic.) 20101201
Title: [Effect of rapamycin on proliferation of acute myeloid leukemia cell lines HL-60 and HL-60/VCR].
Journal: Zhongguo shi yan xue ye xue za zhi 20101201
Title: [mTOR, the mammalian target of rapamycin].
Journal: Medecine sciences : M/S 20101201
Title: More than 4 years of progression-free survival in a patient with metastatic renal cell carcinoma treated sequentially with sunitinib, everolimus, sorafenib, and temsirolimus.
Journal: Anticancer research 20101201
Title: DNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescence.
Journal: Aging 20101201
Title: [A case report of very late thrombosis in two sirolimus-eluting stents].
Journal: Zhonghua xin xue guan bing za zhi 20101201
Title: [Down-regulation of mTOR activity and survivin expression during tamoxifen-induced apoptosis in hepatoblastoma cells].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20101201
Title: Clinical follow-up 3 years after everolimus- and paclitaxel-eluting stents: a pooled analysis from the SPIRIT II (A Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System in the Treatment of Patients With De Novo Native Coronary Artery Lesions) and SPIRIT III (A Clinical Evaluation of the Investigational Device XIENCE V Everolimus Eluting Coronary Stent System [EECSS] in the Treatment of Subjects With De Novo Native Coronary Artery Lesions) randomized trials.
Journal: JACC. Cardiovascular interventions 20101201
Title: Comparison of everolimus-eluting and paclitaxel-eluting coronary stents in patients undergoing multilesion and multivessel intervention: the SPIRIT III (A Clinical Evaluation of the Investigational Device XIENCE V Everolimus Eluting Coronary Stent System [EECSS] in the Treatment of Subjects With De Novo Native Coronary Artery Lesions) and SPIRIT IV (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System in the Treatment of Subjects With De Novo Native Coronary Artery Lesions) randomize
Journal: JACC. Cardiovascular interventions 20101201
Title: Long-term clinical outcomes with zotarolimus-eluting versus bare-metal coronary stents.
Journal: JACC. Cardiovascular interventions 20101201
Title: Temsirolimus and mantle cell lymphoma. Highly toxic, limited efficacy.
Journal: Prescrire international 20101201
Title: High entrapment efficiency of chitosan/polylactic acid/tripolyphotspate nanosized microcapsules for rapamycin by an emulsion-evaporation approach.
Journal: Journal of biomedical nanotechnology 20101201
Title: The AXXESS™ self-expanding biolimus A9™ eluting stent system for coronary bifurcation lesions.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101201
Title: Dedicated everolimus-eluting side branch access system: XIENCE SBA.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101201
Title: Side branch occlusion with everolimus-eluting and paclitaxel-eluting stents: three-year results from the SPIRIT III randomised trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101201
Title: Intracoronary optical coherence tomography and histology at 1 month and 2, 3, and 4 years after implantation of everolimus-eluting bioresorbable vascular scaffolds in a porcine coronary artery model: an attempt to decipher the human optical coherence tomography images in the ABSORB trial.
Journal: Circulation 20101130
Title: Evaluation of the second generation of a bioresorbable everolimus drug-eluting vascular scaffold for treatment of de novo coronary artery stenosis: six-month clinical and imaging outcomes.
Journal: Circulation 20101130
Title: Activation of phosphatidylinositol 3-kinase/Akt-mammalian target of Rapamycin signaling pathway in the hippocampus is essential for the acquisition of morphine-induced place preference in rats.
Journal: Neuroscience 20101124
Title: Sirolimus plus sorafenib in treating HCC recurrence after liver transplantation: a case report.
Journal: World journal of gastroenterology 20101121
Title: Bevacizumab and everolimus in renal cancer: a rational way forward.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101120
Title: Sirolimus- vs. paclitaxel-eluting stents in patients undergoing off-label percutaneous coronary intervention.
Journal: International journal of cardiology 20101119
Title: Multiple cellular proteins modulate the dynamics of K-ras association with the plasma membrane.
Journal: Biophysical journal 20101117
Title: Roles of autophagy in cetuximab-mediated cancer therapy against EGFR.
Journal: Autophagy 20101116
Title: B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer.
Journal: Cancer cell 20101116
Title: A collection of caged compounds for probing roles of local translation in neurobiology.
Journal: Bioorganic & medicinal chemistry 20101115
Title: Sex-specific outcomes following revascularization with zotarolimus-eluting stents: comparison of angiographic and late-term clinical results.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101115
Title: Combination of temsirolimus (CCI-779) with chemoradiation in newly diagnosed glioblastoma multiforme (GBM) (NCCTG trial N027D) is associated with increased infectious risks.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20101115
Title: Comparison of five-year outcome of octogenarians undergoing percutaneous coronary intervention with drug-eluting versus bare-metal stents (from the RESEARCH and T-SEARCH Registries).
Journal: The American journal of cardiology 20101115
Title: Impact of moderate renal insufficiency on restenosis and adverse clinical events after sirolimus-eluting and bare metal stent implantation (from the SIRIUS trials).
Journal: The American journal of cardiology 20101115
Title: Mammalian target of rapamycin-dependent acinar cell neoplasia after inactivation of Apc and Pten in the mouse salivary gland: implications for human acinic cell carcinoma.
Journal: Cancer research 20101115
Title: Gender medicine and drug eluting coronary stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101115
Title: A stress-responsive system for mitochondrial protein degradation.
Journal: Molecular cell 20101112
Title: Akt and autophagy cooperate to promote survival of drug-resistant glioma.
Journal: Science signaling 20101109
Title: Sirolimus-eluting versus bare-metal stent implantation in patients with ostial lesions.
Journal: International journal of cardiology 20101105
Title: Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis.
Journal: The New England journal of medicine 20101104
Title: Precise control of protein concentration in living cells.
Journal: Angewandte Chemie (International ed. in English) 20101102
Title: Inducible somatic oocyte destruction in response to rapamycin requires wild-type regulation of follicle cell epithelial polarity.
Journal: Cell death and differentiation 20101101
Title: Cyclin D1 and cyclin D3 show divergent responses to distinct mitogenic stimulation.
Journal: Journal of cellular physiology 20101101
Title: Evidence for cell cycle-dependent, rapamycin-resistant phosphorylation of ribosomal protein S6 at S240/244.
Journal: Amino acids 20101101
Title: Bortezomib and sirolimus inhibit the chronic active antibody-mediated rejection in experimental renal transplantation in the rat.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101101
Title: Supplementing L-leucine to a low-protein diet increases tissue protein synthesis in weanling pigs.
Journal: Amino acids 20101101
Title: Efficacy and safety of de novo or early everolimus with low cyclosporine in deceased-donor kidney transplant recipients at specified risk of delayed graft function: 12-month results of a randomized, multicenter trial.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20101101
Title: Evaluation of the effects of everolimus-eluting and paclitaxel-eluting stents on target lesions with jailed side branches: 2-year results from the SPIRIT III randomized trial.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101
Title: Comparative effects of sirolimus and cyclosporin on conduit arteries endothelial function in kidney recipients.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20101101
Title: Posttranslational regulation of membrane type 1-matrix metalloproteinase (MT1-MMP) in mouse PTEN null prostate cancer cells: Enhanced surface expression and differential O-glycosylation of MT1-MMP.
Journal: Biochimica et biophysica acta 20101101
Title: Low-dose rapamycin reduces kidney volume angiomyolipomas and prevents the loss of renal function in a patient with tuberous sclerosis complex.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101101
Title: Efficacy of everolimus eluting stent implantation in patients with calcified coronary culprit lesions: two-year angiographic and three-year clinical results from the SPIRIT II study.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101
Title: Maintenance immunosuppressive therapy with everolimus preserves humoral immune responses.
Journal: Kidney international 20101101
Title: Sirolimus immunosuppression for graft-versus-host disease prophylaxis and therapy: an update.
Journal: Current opinion in hematology 20101101
Title: Usefulness of sirolimus-based immunosuppression in ameliorating pre-transplant renal dysfunction in patients with Chagas' heart disease.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20101101
Title: Concurrent involved field radiation therapy and temsirolimus in refractory mantle cell lymphoma (MCL).
Journal: American journal of hematology 20101101
Title: Efficacy and safety/toxicity study of recombinant vaccinia virus JX-594 in two immunocompetent animal models of glioma.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20101101
Title: Lipids and renal cystic disease.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101101
Title: Childhood rhabdomyosarcoma: new insight on biology and treatment.
Journal: Current oncology reports 20101101
Title: Maintenance and consolidation strategies in non-Hodgkin's lymphoma: A review of the data.
Journal: Current oncology reports 20101101
Title: Increased levels of p70S6 phosphorylation in the G93A mouse model of Amyotrophic Lateral Sclerosis and in valine-exposed cortical neurons in culture.
Journal: Experimental neurology 20101101
Title: Temsirolimus has activity in non-mantle cell non-Hodgkin's lymphoma subtypes: The University of Chicago phase II consortium.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101101
Title: An MHC-defined primate model reveals significant rejection of bone marrow after mixed chimerism induction despite full MHC matching.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101101
Title: Antitumor effect of temsirolimus against oral squamous cell carcinoma associated with bone destruction.
Journal: Molecular cancer therapeutics 20101101
Title: Comparisons of the effects of stent eccentricity on the neointimal hyperplasia between sirolimus-eluting stent versus paclitaxel-eluting stent.
Journal: Yonsei medical journal 20101101
Title: Repeated sirolimus-eluting stent implantation to treat sirolimus-eluting stent and bare-metal stent restenosis.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20101101
Title: Comparison of vascular response to zotarolimus-eluting stent vs paclitaxel-eluting stent implantation: pooled IVUS results from the ZoMaxx I and II trials.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20101101
Title: Distinct patterns of autophagy evoked by two benzoxazine derivatives in vascular endothelial cells.
Journal: Autophagy 20101101
Title: STAT3 transcriptional factor activated by reactive oxygen species induces IL6 in starvation-induced autophagy of cancer cells.
Journal: Autophagy 20101101
Title: Inhibition of the mammalian target of rapamycin promotes cyclic AMP-induced differentiation of NG108-15 cells.
Journal: Autophagy 20101101
Title: Three-month dual antiplatelet therapy after implantation of zotarolimus-eluting stents: the DATE (Duration of Dual Antiplatelet Therapy AfterImplantation of Endeavor Stent) registry.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20101101
Title: The use of sirolimus as a rescue therapy in pediatric intestinal transplant recipients.
Journal: Pediatric transplantation 20101101
Title: Activation of Atg1 kinase in autophagy by regulated phosphorylation.
Journal: Autophagy 20101101
Title: Autophagy: a target for retinoic acids.
Journal: Autophagy 20101101
Title: Bevacizumab for metastatic renal cell carcinoma: a monoclonal antibody in a sea of small molecules.
Journal: Expert opinion on biological therapy 20101101
Title: Pharmacologic eigenvalues: beating the rap on bone marrow failure.
Journal: The Journal of clinical investigation 20101101
Title: Phase I study of the oral mammalian target of rapamycin inhibitor everolimus (RAD001) in Japanese patients with relapsed or refractory non-Hodgkin lymphoma.
Journal: International journal of hematology 20101101
Title: Warning: this report does not address heavily calcified coronary arteries.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101
Title: More openness and a little less strut: two good ideas for stents and the people who implant them.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101
Title: Mammalian target of rapamycin complex 1 is involved in differentiation of regenerating myofibers in vivo.
Journal: Muscle & nerve 20101101
Title: Transplantation: can sirolimus prevent skin cancer in transplant recipients?
Journal: Nature reviews. Nephrology 20101101
Title: Comparison of outcomes in patients with insulin-dependent versus non-insulin dependent diabetes mellitus receiving drug-eluting stents (from the first phase of the prospective multicenter German DES.DE registry).
Journal: The American journal of cardiology 20101101
Title: Lack of effect of oral beta-blocker therapy at discharge on long-term clinical outcomes of ST-segment elevation acute myocardial infarction after primary percutaneous coronary intervention.
Journal: The American journal of cardiology 20101101
Title: Could Paclitaxel-eluting stents be superior to sirolimus-eluting stents for the treatment of saphenous vein graft lesions?
Journal: The American journal of cardiology 20101101
Title: Conditionally controlling nuclear trafficking in yeast by chemical-induced protein dimerization.
Journal: Nature protocols 20101101
Title: Differing effects of systemically administered rapamycin on consolidation and reconsolidation of context vs. cued fear memories.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20101101
Title: Impact of insulin-treated diabetes and hemodialysis on long-term clinical outcomes following sirolimus-eluting stent deployment. Insights from a sub-study of the Cypher Stent Japan Post-Marketing Surveillance(Cypher J-PMS) Registry.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20101101
Title: Long-term follow-up of the randomised controlled trial to evaluate the safety and efficacy of the zotarolimus-eluting driver coronary stent in de novo native coronary artery lesions: five year outcomes in the ENDEAVOR II study.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101101
Title: Strut tissue coverage and endothelial cell coverage: a comparison between bare metal stent platforms and platinum chromium stents with and without everolimus-eluting coating.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101101
Title: A phase I dose-escalation study to evaluate safety and tolerability of sorafenib combined with sirolimus in patients with advanced solid cancer.
Journal: British journal of cancer 20101101
Title: The effect of shear stress on neointimal response following sirolimus- and paclitaxel-eluting stent implantation compared with bare-metal stents in humans.
Journal: JACC. Cardiovascular interventions 20101101
Title: A comparison of the conformability of everolimus-eluting bioresorbable vascular scaffolds to metal platform coronary stents.
Journal: JACC. Cardiovascular interventions 20101101
Title: In vivo assessment of local intravascular hemodynamics and arterial morphology to investigate vascular outcomes: a growing field coming of age.
Journal: JACC. Cardiovascular interventions 20101101
Title: Neovascular microchannels in sirolimus-eluting stent occlusion at late phase.
Journal: JACC. Cardiovascular interventions 20101101
Title: Low-dose calcineurin inhibitor regimen combined with mammalian target of rapamycin inhibitors preserves kidney functions in renal transplant recipients without allograft nephropathy.
Journal: Transplantation proceedings 20101101
Title: Malignancies after heart transplantation: incidence, risk factors, and effects of calcineurin inhibitor withdrawal.
Journal: Transplantation proceedings 20101101
Title: Common occurrence of everolimus-associated aphthous stomatitis in Japanese heart transplant recipients.
Journal: Transplantation proceedings 20101101
Title: Use of genetically modified allograft to deliver local immunomodulatory molecule with minimal systemic toxicity in a rat model of allogeneic skin flap transplantation.
Journal: Transplantation proceedings 20101101
Title: Recurrent non-melanoma skin cancer: remission of field cancerization after conversion from calcineurin inhibitor- to proliferation signal inhibitor-based immunosuppression in a cardiac transplant recipient.
Journal: Transplantation proceedings 20101101
Title: Immunoregulation and tolerance.
Journal: Transplantation proceedings 20101101
Title: Can we eliminate both calcineurin inhibitors and steroids?
Journal: Transplantation proceedings 20101101
Title: Rationale for using belatacept in combination with sirolimus.
Journal: Transplantation proceedings 20101101
Title: Can immunosuppressive strategies be used to reduce cancer risk in renal transplant patients?
Journal: Transplantation proceedings 20101101
Title: Clinical insights for cancer outcomes in renal transplant patients.
Journal: Transplantation proceedings 20101101
Title: Regression of left ventricular hypertrophy in kidney transplant recipients: the potential role for inhibition of mammalian target of rapamycin.
Journal: Transplantation proceedings 20101101
Title: Impact of mammalian target of rapamycin inhibition on autosomal-dominant polycystic kidney disease.
Journal: Transplantation proceedings 20101101
Title: The therapy of kidney cancer with biomolecular drugs.
Journal: Cancer treatment reviews 20101101
Title: Biological targeted therapies in patients with advanced enteropancreatic neuroendocrine carcinomas.
Journal: Cancer treatment reviews 20101101
Title: FK506 binding proteins as targets in anticancer therapy.
Journal: Anti-cancer agents in medicinal chemistry 20101101
Title: Ras homolog enriched in brain (Rheb) enhances apoptotic signaling.
Journal: The Journal of biological chemistry 20101029
Title: Descending serotonergic facilitation mediated by spinal 5-HT3 receptors engages spinal rapamycin-sensitive pathways in the rat.
Journal: Neuroscience letters 20101029
Title: Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling.
Journal: Immunity 20101029
Title: mTOR inhibition by everolimus counteracts VEGF induction by sunitinib and improves anti-tumor activity against gastric cancer in vivo.
Journal: Cancer letters 20101028
Title: Assessment of efficacy and safety of FK778 in comparison with standard care in renal transplant recipients with untreated BK nephropathy.
Journal: Transplantation 20101027
Title: [New possibilities of targeted therapy in the treatment of hepatocellular carcinoma with the help of molecular biology].
Journal: Orvosi hetilap 20101024
Title: Phase I studies of drug combinations.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101020
Title: Phase IB study of the mTOR inhibitor ridaforolimus with capecitabine.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101020
Title: Generation of high rapamycin producing strain via rational metabolic pathway-based mutagenesis and further titer improvement with fed-batch bioprocess optimization.
Journal: Biotechnology and bioengineering 20101015
Title: Rapamycin suppresses the expansion and differentiation of porcine neonatal pancreas cell clusters.
Journal: Transplantation 20101015
Title: Combined administration of a mutant TGF-beta1/Fc and rapamycin promotes induction of regulatory T cells and islet allograft tolerance.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20101015
Title: Survival benefit with proapoptotic molecular and pathologic responses from dual targeting of mammalian target of rapamycin and epidermal growth factor receptor in a preclinical model of pancreatic neuroendocrine carcinogenesis.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101010
Title: Small tumors, intermediate models, big hopes.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101010
Title: Steady-state kinetic and inhibition studies of the mammalian target of rapamycin (mTOR) kinase domain and mTOR complexes.
Journal: Biochemistry 20101005
Title: Comparison of zotarolimus-eluting stents with sirolimus- and paclitaxel-eluting stents for coronary revascularization: the ZEST (comparison of the efficacy and safety of zotarolimus-eluting stent with sirolimus-eluting and paclitaxel-eluting stent for coronary lesions) randomized trial.
Journal: Journal of the American College of Cardiology 20101005
Title: Tacrolimus-eluting carbon-coated stents versus sirolimus-eluting stents for prevention of symptom-driven clinical end points.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20101001
Title: Rapamycin sensitizes Akt inhibition in malignant human breast epithelial cells.
Journal: Cancer letters 20101001
Title: Autoimmune cytopaenia after paediatric intestinal transplantation: a case series.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20101001
Title: Early withdrawal of calcineurin inhibitors and everolimus monotherapy in de novo liver transplant recipients preserves renal function.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101001
Title: A phase I-II study of everolimus (RAD001) in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20101001
Title: Sirolimus oral ulcer with Cedecea davisae superinfection.
Journal: Transplant infectious disease : an official journal of the Transplantation Society 20101001
Title: Sirolimus addition to tacrolimus-based immunosuppression induces complete remission of post-transplant lymphoproliferative disorder in a liver transplant recipient.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20101001
Title: Amyloid-beta oligomers impair fear conditioned memory in a calcineurin-dependent fashion in mice.
Journal: Journal of neuroscience research 20101001
Title: Immunosuppressive therapy and infection after kidney transplantation.
Journal: Transplant infectious disease : an official journal of the Transplantation Society 20101001
Title: Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy.
Journal: Neurobiology of disease 20101001
Title: Influence of combined treatment of low dose rapamycin and cyclosporin A on corneal allograft survival.
Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20101001
Title: Activation of mammalian target of rapamycin signaling in spatial learning.
Journal: Neuroscience research 20101001
Title: Gingival overgrowth in subjects under immunosuppressive regimens based on cyclosporine, tacrolimus, or sirolimus.
Journal: Journal of clinical periodontology 20101001
Title: Novel mechanism of reducing tumourigenesis: upregulation of the DNA repair enzyme OGG1 by rapamycin-mediated AMPK activation and mTOR inhibition.
Journal: European journal of cancer (Oxford, England : 1990) 20101001
Title: Evaluation of two sirolimus assays using the ARCHITECT-i1000(®) CMIA or RxL(®) ACMIA methods in comparison with the IMx(®) MEIA method.
Journal: Clinical chemistry and laboratory medicine 20101001
Title: β-Amyloid regulates leptin expression and tau phosphorylation through the mTORC1 signaling pathway.
Journal: Journal of neurochemistry 20101001
Title: Activation of the mammalian target of rapamycin signaling pathway in hepatocellular carcinoma.
Journal: Hepatology (Baltimore, Md.) 20101001
Title: Sirolimus attenuates disease progression in an orthologous mouse model of human autosomal dominant polycystic kidney disease.
Journal: Kidney international 20101001
Title: Short- and mid-term intravascular ultrasound analysis of the new zotarolimus-eluting stent with durable polymer – results from the RESOLUTE trial –.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20101001
Title: Biological agents in kidney transplantation: belatacept is entering the field.
Journal: Expert opinion on biological therapy 20101001
Title: Angiographic, IVUS and OCT evaluation of the long-term impact of coronary disease severity at the site of overlapping drug-eluting and bare metal stents: a substudy of the ODESSA trial.
Journal: Heart (British Cardiac Society) 20101001
Title: Effect of rapamycin, an mTOR inhibitor, on radiation sensitivity of lung cancer cells having different p53 gene status.
Journal: International journal of oncology 20101001
Title: Use of sirolimus in liver transplant recipients with renal insufficiency: a systematic review and meta-analysis.
Journal: Hepatology (Baltimore, Md.) 20101001
Title: Autophagy-induced regression of hyaloid vessels in early ocular development.
Journal: Autophagy 20101001
Title: Late vascular responses from 2 to 4 years after implantation of sirolimus-eluting stents: serial observations by intracoronary optical coherence tomography.
Journal: Circulation. Cardiovascular interventions 20101001
Title: Temsirolimus: In relapsed and/or refractory mantle cell lymphoma.
Journal: Drugs 20101001
Title: De novo therapy with everolimus, low-dose ciclosporine A, basiliximab and steroid elimination in pediatric kidney transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101001
Title: Loss of nephrin expression in glomeruli of kidney-transplanted patients under m-TOR inhibitor therapy.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101001
Title: 18F-FLT PET as a surrogate marker of drug efficacy during mTOR inhibition by everolimus in a preclinical cisplatin-resistant ovarian tumor model.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20101001
Title: Intravascular ultrasound findings of stent fractures in patients with Sirolimus- and Paclitaxel-eluting stents.
Journal: The American journal of cardiology 20101001
Title: Monitoring molecular-specific pharmacodynamics of rapamycin in vivo with inducible Gal4->Fluc transgenic reporter mice.
Journal: Molecular cancer therapeutics 20101001
Title: Phase II trial of gefitinib and everolimus in advanced non-small cell lung cancer.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20101001
Title: Everolimus: a proliferation signal inhibitor with clinical applications in organ transplantation, oncology, and cardiology.
Journal: Pharmacotherapy 20101001
Title: Rapamycin regulates stearoyl CoA desaturase 1 expression in breast cancer.
Journal: Molecular cancer therapeutics 20101001
Title: Effect of sirolimus on renal injury induced by bile duct ligation in rats.
Journal: Acta cirurgica brasileira 20101001
Title: Diaphragm rupture in a liver transplant patient receiving chronic immunosuppressive therapy with sirolimus.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20101001
Title: Rapamycin as an alternative to surgical treatment of subependymal giant cell astrocytomas in a patient with tuberous sclerosis complex.
Journal: Journal of neurosurgery. Pediatrics 20101001
Title: Dramatic improvement in pulmonary hypertension with rapamycin.
Journal: Chest 20101001
Title: Does early (CNI) conversion lead to eternal (renal) salvation?
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101001
Title: Rapid adoption of drug-eluting stents: clinical practices and outcomes from the early drug-eluting stent era.
Journal: American heart journal 20101001
Title: Serial angiographic findings and prognosis of stent fracture site without early restenosis after sirolimus-eluting stent implantation.
Journal: American heart journal 20101001
Title: Oct1 is required for mTOR-induced G1 cell cycle arrest via the control of p27(Kip1) expression.
Journal: Cell cycle (Georgetown, Tex.) 20101001
Title: Current status of the Xience V® everolimus-eluting coronary stent system.
Journal: Expert review of cardiovascular therapy 20101001
Title: Paclitaxel-coated balloons - Survey of preclinical data.
Journal: Minerva cardioangiologica 20101001
Title: Two-year clinical outcomes after large coronary stent (4.0 mm) placement: comparison of bare-metal stent versus drug-eluting stent.
Journal: Clinical cardiology 20101001
Title: Improved late clinical safety with zotarolimus-eluting stents compared with paclitaxel-eluting stents in patients with de novo coronary lesions: 3-year follow-up from the ENDEAVOR IV (Randomized Comparison of Zotarolimus- and Paclitaxel-Eluting Stents in Patients With Coronary Artery Disease) trial.
Journal: JACC. Cardiovascular interventions 20101001
Title: The unrestricted use of sirolimus- and paclitaxel-eluting stents results in better clinical outcomes during 6-year follow-up than bare-metal stents: an analysis of the RESEARCH (Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital) and T-SEARCH (Taxus-Stent Evaluated At Rotterdam Cardiology Hospital) registries.
Journal: JACC. Cardiovascular interventions 20101001
Title: Different patterns of vascular response between patients with or without diabetes mellitus after drug-eluting stent implantation: optical coherence tomographic analysis.
Journal: JACC. Cardiovascular interventions 20101001
Title: Late conversion to mammalian target of rapamycin inhibitor/proliferation signal inhibitors in kidney transplant patients: clinical experience in the last 5 years.
Journal: Transplantation proceedings 20101001
Title: Proliferation signal inhibitors in heart transplantation: a 5-year experience.
Journal: Transplantation proceedings 20101001
Title: Temporal trends in the use of proliferation signal inhibitors in maintenance heart transplantation: a Spanish multicenter study.
Journal: Transplantation proceedings 20101001
Title: Evaluation of a fully automated method for the determination of sirolimus.
Journal: Transplantation proceedings 20101001
Title: Comparative analysis of adverse events requiring suspension of mTOR inhibitors: everolimus versus sirolimus.
Journal: Transplantation proceedings 20101001
Title: Pneumonitis associated with mammalian target of rapamycin inhibitors in renal transplant recipients: a single-center experience.
Journal: Transplantation proceedings 20101001
Title: Clinical outcomes and cost-utility after sirolimus-eluting versus bare metal stent implantation.
Journal: Chinese medical journal 20101001
Title: Androgen receptor-mTOR crosstalk is regulated by testosterone availability: implication for prostate cancer cell survival.
Journal: Anticancer research 20101001
Title: Antiproliferative effects of rapamycin and celecoxib in angiosarcoma cell lines.
Journal: Anticancer research 20101001
Title: Everolimus for the second-line treatment of advanced and/or metastatic renal cell cancer: a critique of the submission from Novartis.
Journal: Health technology assessment (Winchester, England) 20101001
Title: Modulation of ghrelin O-acyltransferase expression in pancreatic islets.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20101001
Title: Comment on 'Infantile spasms: a U.S. consensus report'.
Journal: Epilepsia 20101001
Title: Rapamycin protects heart from ischemia/reperfusion injury independent of autophagy by activating PI3 kinase-Akt pathway and mitochondria K(ATP) channel.
Journal: Die Pharmazie 20101001
Title: [Efficacy comparison of primary percutaneous coronary intervention with biodegradable polymer- and durable polymer-based sirolimus-eluting stents for patients with acute myocardial infarction].
Journal: Zhonghua xin xue guan bing za zhi 20101001
Title: Combination therapy in patients with metastatic renal cell carcinoma.
Journal: Clinical advances in hematology & oncology : H&O 20101001
Title: Recent advances in the discovery of small molecule mTOR inhibitors.
Journal: Future medicinal chemistry 20101001
Title: Prolonging hormone sensitivity in prostate cancer xenografts through dual inhibition of AR and mTOR.
Journal: British journal of cancer 20100928
Title: Improvement in renal function after late conversion to sirolimus-based immunosuppression in composite tissue allotransplantation.
Journal: Transplantation 20100927
Title: Clinical outcomes after implantation of small diameter (=2.5 mm) sirolimus- versus paclitaxel-eluting stents.
Journal: International journal of cardiology 20100924
Title: Dual-color click beetle luciferase heteroprotein fragment complementation assays.
Journal: Chemistry & biology 20100924
Title: [Everolimus-associated pneumonitis in adult liver transplant recipient].
Journal: Medicina clinica 20100918
Title: Phase 3 trial of everolimus for metastatic renal cell carcinoma : final results and analysis of prognostic factors.
Journal: Cancer 20100915
Title: Visceral Kaposi's sarcoma remission after intestinal transplant. First case report and systematic literature review.
Journal: Transplantation 20100915
Title: Effect of coronary target lesion revascularization on late cardiac events after insertion of sirolimus-eluting or bare metal stents.
Journal: The American journal of cardiology 20100915
Title: Safety and efficacy of the combination of erlotinib and sirolimus for the treatment of metastatic renal cell carcinoma after failure of sunitinib or sorafenib.
Journal: British journal of cancer 20100907
Title: Treatment of prostate and breast tumors employing mono- and bi-specific antisense oligonucleotides targeting apoptosis inhibitory proteins clusterin and bcl-2.
Journal: Medical oncology (Northwood, London, England) 20100901
Title: Spontaneous pyopneumothorax in patients treated with mTOR inhibitors for subpleural pulmonary metastases.
Journal: Medical oncology (Northwood, London, England) 20100901
Title: Targeted agents in metastatic Xp11 translocation/TFE3 gene fusion renal cell carcinoma (RCC): a report from the Juvenile RCC Network.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20100901
Title: Combination of clopidogrel and everolimus dramatically reduced the development of transplant arteriosclerosis in murine aortic allografts.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100901
Title: Phosphorylated mTOR expression is associated with poor prognosis for patients with esophageal squamous cell carcinoma.
Journal: Annals of surgical oncology 20100901
Title: Compensatory activation of Akt in response to mTOR and Raf inhibitors - a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease.
Journal: Cancer letters 20100901
Title: Rapamycin-induced phosphaturia.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100901
Title: Cell-type- and cell-cycle-specific anti-mitogenesis by cicaprost.
Journal: Prostaglandins & other lipid mediators 20100901
Title: Severe sirolimus-induced acute hepatitis in a renal transplant recipient.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100901
Title: Identification of p27/KIP1 expression level as a candidate biomarker of response to rapalogs therapy in human cancer.
Journal: Journal of molecular medicine (Berlin, Germany) 20100901
Title: Everolimus as a new potential antiproliferative agent in aggressive human bronchial carcinoids.
Journal: Endocrine-related cancer 20100901
Title: Rapamycin induces growth retardation by disrupting angiogenesis in the growth plate.
Journal: Kidney international 20100901
Title: Bevacizumab and everolimus in the treatment of patients with metastatic melanoma: a phase 2 trial of the Sarah Cannon Oncology Research Consortium.
Journal: Cancer 20100901
Title: Antiproliferation of cardamonin is involved in mTOR on aortic smooth muscle cells in high fructose-induced insulin resistance rats.
Journal: European journal of pharmacology 20100901
Title: Coronary microvascular endothelial function deteriorates late (12 months) after sirolimus-eluting stent implantation.
Journal: Journal of cardiology 20100901
Title: Choice of stenting strategy in true coronary artery bifurcation lesions.
Journal: Coronary artery disease 20100901
Title: Cutaneous T-cell lymphoma cells are sensitive to rapamycin.
Journal: Experimental dermatology 20100901
Title: Pilot study: rapamycin in advanced hepatocellular carcinoma.
Journal: Alimentary pharmacology & therapeutics 20100901
Title: Human chorionic gonadotropin stimulates theca-interstitial cell proliferation and cell cycle regulatory proteins by a cAMP-dependent activation of AKT/mTORC1 signaling pathway.
Journal: Molecular endocrinology (Baltimore, Md.) 20100901
Title: Everolimus: efficacy and safety in cardiac transplantation.
Journal: Expert opinion on drug safety 20100901
Title: Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens.
Journal: EMBO molecular medicine 20100901
Title: Autophagy induction with RAD001 enhances chemosensitivity and radiosensitivity through Met inhibition in papillary thyroid cancer.
Journal: Molecular cancer research : MCR 20100901
Title: Rapamycin and thalidomide treatment of a patient with refractory metastatic gastroesophageal adenocarcinoma: a case report.
Journal: The oncologist 20100901
Title: [Second line AUO study AB35/09 of metastasized urothelial cell carcinoma].
Journal: Der Urologe. Ausg. A 20100901
Title: Can autophagy promote longevity?
Journal: Nature cell biology 20100901
Title: Updates of mTOR inhibitors.
Journal: Anti-cancer agents in medicinal chemistry 20100901
Title: Vulnerable disease may induce neointimal coverage after sirolimus-eluting stent implantation.
Journal: American heart journal 20100901
Title: Everolimus-eluting stents: insights from the SPIRIT IV and COMPARE trials.
Journal: Expert review of cardiovascular therapy 20100901
Title: Percutaneous coronary intervention for small-vessel coronary disease: highlight on the everolimus-eluting stent.
Journal: Expert review of cardiovascular therapy 20100901
Title: Bone disease in renal transplantation and pleotropic effects of vitamin D therapy.
Journal: Transplantation proceedings 20100901
Title: Sirolimus-induced isometric tubular vacuolization: a new sirolimus histopathologic manifestation.
Journal: Transplantation proceedings 20100901
Title: Timing of conversion to mammalian target of rapamycin inhibitors is crucial in liver transplant recipients with impaired renal function at transplantation.
Journal: Transplantation proceedings 20100901
Title: Sirolimus in liver transplant recipients: a large single-center experience.
Journal: Transplantation proceedings 20100901
Title: Influence of immunosuppressive drugs on the development of CD4(+)CD25(high) Foxp3(+) T cells in liver transplant recipients.
Journal: Transplantation proceedings 20100901
Title: Sirolimus is associated with impaired hematopoiesis in heart transplant patients? A retrospective analysis.
Journal: Transplantation proceedings 20100901
Title: American Society of Clinical Oncology 2010: report of selected studies from the CNS tumors section.
Journal: Expert review of anticancer therapy 20100901
Title: Comparison of sirolimus- and paclitaxel-eluting stents in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction: a meta-analysis of randomized trials.
Journal: Clinical cardiology 20100901
Title: mTOR pathway inhibitors in cancer therapy: moving past rapamycin.
Journal: Pharmacogenomics 20100901
Title: Rapamycin and MPA, but not CsA, impair human NK cell cytotoxicity due to differential effects on NK cell phenotype.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100901
Title: Comparison of everolimus-eluting and paclitaxel-eluting coronary stents in patients with two treated vessels: 2-year results from the SPIRIT III randomised trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100901
Title: Three-year results of clinical follow-up after a bioresorbable everolimus-eluting scaffold in patients with de novo coronary artery disease: the ABSORB trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100901
Title: Impact of arterial injury on neointimal hyperplasia after implantation of drug-eluting stents in coronary arteries: an intravascular ultrasound study.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100901
Title: Vascular response to a third generation everolimus-eluting stent.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100901
Title: Differential expression of mTOR signalling components in drug resistance in ovarian cancer.
Journal: Anticancer research 20100901
Title: Ridaforolimus.
Journal: Drugs in R&D 20100901
Title: Inflammation inhibitory effects of sirolimus and paclitaxel-eluting stents on interleukin-1β-induced coronary artery in-stent restenosis in pigs.
Journal: Chinese medical journal 20100901
Title: [Inhibition of cell growth by rapamycin through targeting mammalian target of rapamycin signaling pathway in nasopharyngeal carcinoma].
Journal: Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20100901
Title: Antihyperalgesic and antiallodynic effect of sirolimus in neuropathic pain and the role of cytokines in this effect.
Journal: Neuroscience letters 20100830
Title: Murine cytomegalovirus infection leads to increased levels of transplant arteriosclerosis in a murine aortic allograft model.
Journal: Transplantation 20100827
Title: Sirolimus and kidney growth in autosomal dominant polycystic kidney disease.
Journal: The New England journal of medicine 20100826
Title: Everolimus in patients with autosomal dominant polycystic kidney disease.
Journal: The New England journal of medicine 20100826
Title: mTOR inhibitors in polycystic kidney disease.
Journal: The New England journal of medicine 20100826
Title: Rapamycin activates autophagy and improves myelination in explant cultures from neuropathic mice.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100825
Title: Integrated preclinical and clinical development of mTOR inhibitors in pancreatic cancer.
Journal: British journal of cancer 20100824
Title: Dual inhibition of EGFR and mTOR pathways in small cell lung cancer.
Journal: British journal of cancer 20100824
Title: Regulation of the autophagy protein LC3 by phosphorylation.
Journal: The Journal of cell biology 20100823
Title: Resistance to mammalian target of rapamycin inhibitor therapy in perivascular epithelioid cell tumors.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100820
Title: Neuroscience. A glutamate pathway to faster-acting antidepressants?
Journal: Science (New York, N.Y.) 20100820
Title: mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists.
Journal: Science (New York, N.Y.) 20100820
Title: Correlation of tissue drug concentrations with in vivo magnetic resonance images of polymer drug depot around arteriovenous graft.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20100817
Title: Early and late effects of the immunosuppressants rapamycin and mycophenolate mofetil on UV carcinogenesis.
Journal: International journal of cancer 20100815
Title: Phase 1 and pharmacokinetic study of everolimus, a mammalian target of rapamycin inhibitor, in combination with docetaxel for recurrent/refractory nonsmall cell lung cancer.
Journal: Cancer 20100815
Title: Intermittent antibody-based combination therapy removes alloantibodies and achieves indefinite heart transplant survival in presensitized recipients.
Journal: Transplantation 20100815
Title: Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20100815
Title: Manipulating signal delivery - plasma-membrane ERK activation in aPKC-dependent migration.
Journal: Journal of cell science 20100815
Title: Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer.
Journal: Cancer research 20100815
Title: Comparison of everolimus- versus paclitaxel-eluting stents implanted in patients with diabetes mellitus as evaluated by three-dimensional intravascular ultrasound analysis.
Journal: The American journal of cardiology 20100815
Title: Three-year outcomes following sirolimus- versus paclitaxel-eluting stent implantation in an unselected population with coronary artery disease (from the REWARDS Registry).
Journal: The American journal of cardiology 20100815
Title: A novel clinically relevant approach to tip the balance toward regulation in stringent transplant model.
Journal: Transplantation 20100815
Title: Revisiting the antagonistic pleiotropy theory of aging: TOR-driven program and quasi-program.
Journal: Cell cycle (Georgetown, Tex.) 20100815
Title: Altered VEGF mRNA stability following treatments with immunosuppressive agents: implications for cancer development.
Journal: The Journal of biological chemistry 20100813
Title: A novel Ca2+/calmodulin antagonist HBC inhibits angiogenesis and down-regulates hypoxia-inducible factor.
Journal: The Journal of biological chemistry 20100813
Title: MLK3 is critical for breast cancer cell migration and promotes a malignant phenotype in mammary epithelial cells.
Journal: Oncogene 20100805
Title: Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus.
Journal: The Journal of clinical investigation 20100802
Title: PIK3CA and KRAS mutations predict for response to everolimus therapy: now that's RAD001.
Journal: The Journal of clinical investigation 20100802
Title: The activity of mTOR inhibitor RAD001 (everolimus) in nasopharyngeal carcinoma and cisplatin-resistant cell lines.
Journal: Investigational new drugs 20100801
Title: Large-scale expansion of pluripotent human embryonic stem cells in stirred-suspension bioreactors.
Journal: Tissue engineering. Part C, Methods 20100801
Title: Sirolimus attenuates reduced-size liver ischemia-reperfusion injury but impairs liver regeneration in rats.
Journal: Digestive diseases and sciences 20100801
Title: Enzastaurin (LY317615), a protein kinase C beta selective inhibitor, enhances antiangiogenic effect of radiation.
Journal: International journal of radiation oncology, biology, physics 20100801
Title: Effect of everolimus on skin cancers in calcineurin inhihitor-treated heart transplant recipients.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100801
Title: Fatal diffuse alveolar hemorrhage associated with sirolimus after allogeneic hematopoietic cell transplantation.
Journal: Bone marrow transplantation 20100801
Title: Sirolimus for treatment of steroid-refractory acute graft-versus-host disease.
Journal: Bone marrow transplantation 20100801
Title: Sirolimus in renal transplant recipients with tuberous sclerosis complex: clinical effectiveness and implications for innate immunity.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100801
Title: Combination of tipifarnib and rapamycin synergistically inhibits the growth of leukemia cells and overcomes resistance to tipifarnib via alteration of cellular signaling pathways.
Journal: Leukemia research 20100801
Title: Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells.
Journal: Breast cancer research and treatment 20100801
Title: Noninfectious pneumonitis after everolimus therapy for advanced renal cell carcinoma.
Journal: American journal of respiratory and critical care medicine 20100801
Title: Neoadjuvant temsirolimus effectiveness in downstaging advanced non-clear cell renal cell carcinoma.
Journal: European urology 20100801
Title: IGFBP-2 expression in MCF-7 cells is regulated by the PI3K/AKT/mTOR pathway through Sp1-induced increase in transcription.
Journal: Growth factors (Chur, Switzerland) 20100801
Title: Surface characterization of poly(lactic acid)/everolimus and poly(ethylene vinyl alcohol)/everolimus stents.
Journal: Drug delivery 20100801
Title: Inhibition of mTORC1 by RAD001 (everolimus) potentiates the effects of 1,25-dihydroxyvitamin D(3) to induce growth arrest and differentiation of AML cells in vitro and in vivo.
Journal: Experimental hematology 20100801
Title: Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice.
Journal: Gastroenterology 20100801
Title: A spectrophotometric assay for routine measurement of mammalian target of rapamycin activity in cell lysates.
Journal: Analytical biochemistry 20100801
Title: A Phase 1 clinical study of temsirolimus (CCI-779) in Japanese patients with advanced solid tumors.
Journal: Japanese journal of clinical oncology 20100801
Title: Drug-eluting stents ameliorate pulmonary vein stenotic changes in pigs in vivo.
Journal: Pediatric cardiology 20100801
Title: Sirolimus has a potential to influent viral recurrence in HCV positive liver transplant candidates.
Journal: International immunopharmacology 20100801
Title: Pulmonary alveolar proteinosis in a kidney transplant: a rare complication of sirolimus.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100801
Title: Endocrine control of oleic acid and glucose metabolism in rainbow trout (Oncorhynchus mykiss) muscle cells in culture.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100801
Title: Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis.
Journal: Arthritis and rheumatism 20100801
Title: Treatment with rapamycin prevents fibrosis in tight-skin and bleomycin-induced mouse models of systemic sclerosis.
Journal: Arthritis and rheumatism 20100801
Title: Increased serum vWF and sVCAM-1 levels are associated with late or very late angiographic stent thrombosis after sirolimus-eluting stent implantation.
Journal: Coronary artery disease 20100801
Title: Intravascular ultrasound criteria for determination of optimal longitudinal positioning of sirolimus-eluting stents.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20100801
Title: Liquid chromatography-tandem mass spectrometry outperforms fluorescence polarization immunoassay in monitoring everolimus therapy in renal transplantation.
Journal: Therapeutic drug monitoring 20100801
Title: Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined with rapamycin.
Journal: Leukemia 20100801
Title: Effects of sirolimus alone or in combination with cyclosporine A on renal ischemia/reperfusion injury.
Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20100801
Title: Protein denaturation and protein:drugs interactions from intrinsic protein fluorescence measurements at the nanolitre scale.
Journal: Protein science : a publication of the Protein Society 20100801
Title: Inhibition of glycogen biosynthesis via mTORC1 suppression as an adjunct therapy for Pompe disease.
Journal: Molecular genetics and metabolism 20100801
Title: Beclin 1 self-association is independent of autophagy induction by amino acid deprivation and rapamycin treatment.
Journal: Journal of cellular biochemistry 20100801
Title: Comparison of sirolimus-eluting and bare metal stent for treatment of patients with total coronary occlusions: results of the GISSOC II-GISE multicentre randomized trial.
Journal: European heart journal 20100801
Title: New inhibitors of the mammalian target of rapamycin signaling pathway for cancer.
Journal: Expert opinion on investigational drugs 20100801
Title: Sirolimus and mycophenolate as combination prophylaxis in corneal transplant recipients at high rejection risk.
Journal: American journal of ophthalmology 20100801
Title: TSC1/2 tumour suppressor complex maintains Drosophila germline stem cells by preventing differentiation.
Journal: Development (Cambridge, England) 20100801
Title: The application of the National Institute of Clinical Excellence guidelines for treatment of metastatic renal cell carcinoma in the United Kingdom: friend or foe?
Journal: BJU international 20100801
Title: Biosynthesis of rapamycin and its regulation: past achievements and recent progress.
Journal: The Journal of antibiotics 20100801
Title: Differential proteome and phosphoproteome signatures in human T-lymphoblast cells induced by sirolimus.
Journal: Cell proliferation 20100801
Title: In vitro effects of everolimus and intravenous immunoglobulin on cell proliferation and apoptosis induction in the mixed lymphocyte reaction.
Journal: Transplant immunology 20100801
Title: Do drug elution components increase the risk of fracture of sirolimus-eluting stents?
Journal: Coronary artery disease 20100801
Title: Conversion to sirolimus in renal transplant recipients: a single-center experience.
Journal: Artificial organs 20100801
Title: Everolimus in the treatment of renal cell carcinoma and neuroendocrine tumors.
Journal: Advances in therapy 20100801
Title: Rapamycin-conditioned donor dendritic cells differentiate CD4CD25Foxp3 T cells in vitro with TGF-beta1 for islet transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100801
Title: Incidence and risk factors of late target lesion revascularization after sirolimus-eluting stent implantation (3-year follow-up of the j-Cypher Registry).
Journal: The American journal of cardiology 20100801
Title: Comparison of sirolimus-eluting stents with paclitaxel-eluting stents in saphenous vein graft intervention (from a multicenter Southern California Registry).
Journal: The American journal of cardiology 20100801
Title: The combination of multiple receptor tyrosine kinase inhibitor and mammalian target of rapamycin inhibitor overcomes erlotinib resistance in lung cancer cell lines through c-Met inhibition.
Journal: Molecular cancer research : MCR 20100801
Title: Progeria syndromes and ageing: what is the connection?
Journal: Nature reviews. Molecular cell biology 20100801
Title: Islet transplantation in type 1 diabetics using an immunosuppressive protocol based on the anti-LFA-1 antibody efalizumab.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100801
Title: Off-label prescribing: a matter of trust.
Journal: Nature reviews. Nephrology 20100801
Title: Elevated high sensitive C-reactive protein and apelin levels after percutaneous coronary intervention and drug-eluting stent implantation.
Journal: Journal of Zhejiang University. Science. B 20100801
Title: Very late thrombosis after subintimal sirolimus-eluting stent implantation during percutaneous coronary intervention for chronic total occlusion.
Journal: The Journal of invasive cardiology 20100801
Title: Primary use of sirolimus-eluting stents in the infrapopliteal arteries.
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20100801
Title: Commentary: infrapopliteal angioplasty with drug-eluting stents: from heart to toe.
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20100801
Title: Xenohormetic, hormetic and cytostatic selective forces driving longevity at the ecosystemic level.
Journal: Aging 20100801
Title: How does the mammalian target of rapamycin (mTOR) influence CD8 T cell differentiation?
Journal: Cell cycle (Georgetown, Tex.) 20100801
Title: Different patterns of BK and JC polyomavirus reactivation following renal transplantation.
Journal: Journal of clinical pathology 20100801
Title: Targeted therapy at the end of life for patients with lung cancer.
Journal: Journal of palliative medicine 20100801
Title: New drug-eluting stents: an overview on biodegradable and polymer-free next-generation stent systems.
Journal: Circulation. Cardiovascular interventions 20100801
Title: 3-Dimensional optical coherence tomography assessment of jailed side branches by bioresorbable vascular scaffolds: a proposal for classification.
Journal: JACC. Cardiovascular interventions 20100801
Title: Effect of oral sirolimus therapy on inflammatory biomarkers following coronary stenting.
Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20100801
Title: Arnold Lester Demain: a good friend, an outstanding scientist and a valuable professor.
Journal: The Journal of antibiotics 20100801
Title: Everolimus in renal cell carcinoma.
Journal: Drugs of today (Barcelona, Spain : 1998) 20100801
Title: Short and long term comparison (24 months) of an alternative sirolimus-coated stent with bioabsorbable polymer and a bare metal stent of similar design in chronic coronary occlusions: the CORACTO trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100801
Title: Intravascular ultrasound, angioscopic and histopathological characterisation of heterogeneous patterns of restenosis after sirolimus-eluting stent implantation: insights into potential 'thromborestenosis' phenomenon.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100801
Title: A quantitative coronary angiography-matched comparison between a prospective randomised multicentre cutting balloon angioplasty and bare metal stent trial (REDUCE III) and the Rapamycin-Eluting Stent Evaluation At Rotterdam Cardiology Hospital (RESEARCH) study.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100801
Title: The combination of sirolimus and rosiglitazone produces a renoprotective effect on diabetic kidney disease in rats.
Journal: Life sciences 20100731
Title: Rapamycin promotes beta-amyloid production via ADAM-10 inhibition.
Journal: Biochemical and biophysical research communications 20100730
Title: Modulation of high-voltage activated Ca(2+) channels by membrane phosphatidylinositol 4,5-bisphosphate.
Journal: Neuron 20100729
Title: Renal function, efficacy, and safety of sirolimus and mycophenolate mofetil after short-term calcineurin inhibitor-based quadruple therapy in de novo renal transplant patients: one-year analysis of a randomized multicenter trial.
Journal: Transplantation 20100727
Title: Effect of sirolimus on calcineurin inhibitor-induced nephrotoxicity using renal expression of KLOTHO, an antiaging gene.
Journal: Transplantation 20100727
Title: The TOR complex 1 is distributed in endosomes and in retrograde vesicles that form from the vacuole membrane and plays an important role in the vacuole import and degradation pathway.
Journal: The Journal of biological chemistry 20100723
Title: Identification of Pep4p as the protease responsible for formation of the SAGA-related SLIK protein complex.
Journal: The Journal of biological chemistry 20100723
Title: [Chronic renal failure is associated with worse outcome after implantation of sirolimus eluting stent].
Journal: Medicina clinica 20100717
Title: Selective induction of catalase-mediated autophagy by dihydrocapsaicin in lung cell lines.
Journal: Free radical biology & medicine 20100715
Title: Enteric-coated mycophenolate sodium versus mycophenolate mofetil maintenance immunosuppression: outcomes analysis of the United Network for Organ Sharing/Organ Procurement and Transplantation Network database.
Journal: Transplantation 20100715
Title: R1507, a fully human monoclonal antibody targeting IGF-1R, is effective alone and in combination with rapamycin in inhibiting growth of osteosarcoma xenografts.
Journal: Pediatric blood & cancer 20100715
Title: Optimal everolimus concentration is associated with risk reduction for acute rejection in de novo renal transplant recipients.
Journal: Transplantation 20100715
Title: mTORC1 signaling in Parkinson's disease and L-DOPA-induced dyskinesia: A sensitized matter.
Journal: Cell cycle (Georgetown, Tex.) 20100715
Title: The efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 compared with rapamycin in renal cell carcinoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100715
Title: Comparison of zotarolimus-eluting and everolimus-eluting coronary stents.
Journal: The New England journal of medicine 20100708
Title: Sirolimus-eluting stent versus balloon angioplasty for sirolimus-eluting stent restenosis: Insights from the j-Cypher Registry.
Journal: Circulation 20100706
Title: Comparisons of baseline demographics, clinical presentation, and long-term outcome among patients with early, late, and very late stent thrombosis of sirolimus-eluting stents: Observations from the Registry of Stent Thrombosis for Review and Reevaluation (RESTART).
Journal: Circulation 20100706
Title: Sirolimus therapy for fibromatosis and multifocal renal cell carcinoma in a child with tuberous sclerosis complex.
Journal: Pediatric blood & cancer 20100701
Title: Effect of combination treatment of rapamycin and isoflavones on mTOR pathway in human glioblastoma (U87) cells.
Journal: Neurochemical research 20100701
Title: Antiangiogenic effects and transcriptional regulation of pigment epithelium-derived factor in diabetic retinopathy.
Journal: Microvascular research 20100701
Title: Inhibition of MEK/ERK signaling induces apoptosis of acute myelogenous leukemia cells via inhibition of eukaryotic initiation factor 4E-binding protein 1 and down-regulation of Mcl-1.
Journal: Apoptosis : an international journal on programmed cell death 20100701
Title: Inhibition of mTORC1 signaling reduces tumor growth but does not prevent cancer progression in a mouse model of thyroid cancer.
Journal: Carcinogenesis 20100701
Title: Four-year clinical outcome of sirolimus- and paclitaxel-eluting stents compared to bare-metal stents for the percutaneous treatment of stable coronary artery disease.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701
Title: In vitro and in vivo changes to PLGA/sirolimus coating on drug eluting stents.
Journal: Biomaterials 20100701
Title: MTOR downregulates iodide uptake in thyrocytes.
Journal: The Journal of endocrinology 20100701
Title: Gingival overgrowth in cyclosporine, tacrolimus, or sirolimus-based immunosuppressive regimens and the single nucleotide IL-6 (-174 G/C) gene polymorphism.
Journal: Archives of oral biology 20100701
Title: Regulation of the creatine transporter by AMP-activated protein kinase in kidney epithelial cells.
Journal: American journal of physiology. Renal physiology 20100701
Title: New developments in targeted therapy for soft tissue sarcoma.
Journal: Current oncology reports 20100701
Title: Sirolimus and everolimus reduce albumin endocytosis in proximal tubule cells via an angiotensin II-dependent pathway.
Journal: Transplant immunology 20100701
Title: New drugs in neuroendocrine tumors: rising of new therapeutic philosophies?
Journal: Current opinion in oncology 20100701
Title: Gene expression profiling of response to mTOR inhibitor everolimus in pre-operatively treated post-menopausal women with oestrogen receptor-positive breast cancer.
Journal: Breast cancer research and treatment 20100701
Title: cAMP-dependent activation of mammalian target of rapamycin (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4.
Journal: Molecular endocrinology (Baltimore, Md.) 20100701
Title: Complete resolution of oral Kaposi's sarcoma achieved by changing immunosuppression: a case report.
Journal: Annals of the Royal College of Surgeons of England 20100701
Title: Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor-positive human breast cancer.
Journal: The Journal of clinical investigation 20100701
Title: Visualization of embryonic lymphangiogenesis advances the use of the zebrafish model for research in cancer and lymphatic pathologies.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20100701
Title: Outcomes after differential use of drug-eluting stents in diabetic patients: 1-year results from the DES.DE (Drug-Eluting Stent.DEutschland) registry.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701
Title: Which DES for diabetics? Round 1: A draw. Round 2: Everolimus leading?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701
Title: An everolimus-eluting stent versus a paclitaxel-eluting stent in small vessel coronary artery disease: a pooled analysis from the SPIRIT II and SPIRIT III trials.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701
Title: Another small step for small vessels.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701
Title: [Sirolimus-eluting stent in the prevention of restenosis in small coronary arteries].
Journal: La Tunisie medicale 20100701
Title: Development and performance of the zotarolimus-eluting Endeavor coronary stent.
Journal: Expert review of medical devices 20100701
Title: Effectiveness and safety of drug-eluting stents in a cardiology clinic in Curitiba, PR, Brazil.
Journal: Arquivos brasileiros de cardiologia 20100701
Title: Recent advances in the development of selective, ATP-competitive inhibitors of mTOR.
Journal: Current opinion in drug discovery & development 20100701
Title: Efficacy and safety of rapamycin as compared to paclitaxel-eluting stents: a meta-analysis.
Journal: The Journal of invasive cardiology 20100701
Title: Long-term clinical outcome of sirolimus-eluting stent implantation in metabolic syndrome and diabetes.
Journal: The Journal of invasive cardiology 20100701
Title: Three-year outcome of sirolimus-eluting versus bare-metal stents for the treatment of ST-segment elevation myocardial infarction (from the MISSION! Intervention Study).
Journal: The American journal of cardiology 20100701
Title: SPIRIT III JAPAN versus SPIRIT III USA: a comparative intravascular ultrasound analysis of the everolimus-eluting stent.
Journal: The American journal of cardiology 20100701
Title: Therapeutic approaches to epileptogenesis--hope on the horizon.
Journal: Epilepsia 20100701
Title: Modeling new therapies for infantile spasms.
Journal: Epilepsia 20100701
Title: Clinical recommendations for the use of everolimus in heart transplantation.
Journal: Transplantation reviews (Orlando, Fla.) 20100701
Title: Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes.
Journal: Aging 20100701
Title: [Current impact of natural products in the discovery of anticancer drugs].
Journal: Annales pharmaceutiques francaises 20100701
Title: Influence of immunosuppression on alloresponse, inflammation and contractile function of graft after intestinal transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100701
Title: Therapeutic mTOR inhibition in autosomal dominant polycystic kidney disease: What is the appropriate serum level?
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100701
Title: Topical rapamycin: a novel approach to facial angiofibromas in tuberous sclerosis.
Journal: Archives of dermatology 20100701
Title: Specific coronary drug-eluting stents interfere with distal microvascular function after single stent implantation in pigs.
Journal: JACC. Cardiovascular interventions 20100701
Title: [Subacute thrombosis of drug eluting stent immediately after off-pump coronary artery bypass grafting].
Journal: Kyobu geka. The Japanese journal of thoracic surgery 20100701
Title: Temsirolimus: is improved survival the correct expression of drug activity?
Journal: The oncologist 20100701
Title: Combination therapy of 5-fluorouracil with rapamycin for hormone receptor-negative human breast cancer.
Journal: Anticancer research 20100701
Title: Rapamycin treatment suppresses epileptogenic activity in conditional Pten knockout mice.
Journal: Cell cycle (Georgetown, Tex.) 20100701
Title: Thymoglobulin induction and sirolimus versus tacrolimus in kidney transplant recipients receiving mycophenolate mofetil and steroids.
Journal: Transplantation 20100627
Title: Oxidative stress changes after stent implantation: a randomized comparative study of sirolimus-eluting and bare metal stents.
Journal: International journal of cardiology 20100625
Title: Design of selective, ATP-competitive inhibitors of Akt.
Journal: Journal of medicinal chemistry 20100624
Title: Mammalian target of rapamycin (mTOR) and S6 kinase down-regulate phospholipase D2 basal expression and function.
Journal: The Journal of biological chemistry 20100618
Title: Randomized trial of paclitaxel- versus sirolimus-eluting stents for treatment of coronary restenosis in sirolimus-eluting stents: the ISAR-DESIRE 2 (Intracoronary Stenting and Angiographic Results: Drug Eluting Stents for In-Stent Restenosis 2) study.
Journal: Journal of the American College of Cardiology 20100615
Title: Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks.
Journal: Circulation research 20100611
Title: Structure of the human mTOR complex I and its implications for rapamycin inhibition.
Journal: Molecular cell 20100611
Title: Chemically controlled protein assembly: techniques and applications.
Journal: Chemical reviews 20100609
Title: 2-year clinical and angiographic outcomes from a randomized trial of polymer-free dual drug-eluting stents versus polymer-based Cypher and Endeavor [corrected] drug-eluting stents.
Journal: Journal of the American College of Cardiology 20100608
Title: Distinct phosphatase requirements and GATA factor responses to nitrogen catabolite repression and rapamycin treatment in Saccharomyces cerevisiae.
Journal: The Journal of biological chemistry 20100604
Title: Mechanisms involved in the enhancement of mammalian target of rapamycin signalling and hypertrophy in skeletal muscle of myostatin-deficient mice.
Journal: FEBS letters 20100603
Title: Feasibility of sequential use of sunitinib and temsirolimus in advanced renal cell carcinoma.
Journal: Medical oncology (Northwood, London, England) 20100601
Title: Phase I, pharmacokinetic study of temsirolimus administered orally to patients with advanced cancer.
Journal: Investigational new drugs 20100601
Title: Mammalian target of rapamycin (mTOR) is involved in the survival of cells mediated by chemokine receptor 7 through PI3K/Akt in metastatic squamous cell carcinoma of the head and neck.
Journal: The British journal of oral & maxillofacial surgery 20100601
Title: Gonadal dysfunction and infertility in kidney transplant patients receiving sirolimus.
Journal: International urology and nephrology 20100601
Title: A model of chronic lung allograft rejection in the rat.
Journal: The European respiratory journal 20100601
Title: Rapamycin enhances chemotherapy-induced cytotoxicity by inhibiting the expressions of TS and ERK in gastric cancer cells.
Journal: International journal of cancer 20100601
Title: Phase Ib study of weekly mammalian target of rapamycin inhibitor ridaforolimus (AP23573; MK-8669) with weekly paclitaxel.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20100601
Title: Sirolimus-associated acute interstitial nephritis in a renal allograft.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100601
Title: FAK mediates the activation of cardiac fibroblasts induced by mechanical stress through regulation of the mTOR complex.
Journal: Cardiovascular research 20100601
Title: The role of mTOR signaling in controlling mammalian life span: what a fungicide teaches us about longevity.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20100601
Title: Correlation between circulating endothelial progenitor cell function and allograft rejection in heart transplant patients.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100601
Title: Cyclosporine, tacrolimus and sirolimus retain their distinct toxicity profiles despite low doses in the Symphony study.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100601
Title: Switch to a sirolimus-based immunosuppression in long-term renal transplant recipients: reduced rate of (pre-)malignancies and nonmelanoma skin cancer in a prospective, randomized, assessor-blinded, controlled clinical trial.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100601
Title: Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1.
Journal: Cellular signalling 20100601
Title: Long-term complication after LM bifurcation treatment.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601
Title: Proximal protection in recanalization of totally occluded saphenous vein grafts in acute coronary syndrome.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601
Title: Update on systemic therapies of metastatic renal cell carcinoma.
Journal: World journal of urology 20100601
Title: Reversible severe synovitis associated with everolimus.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20100601
Title: Central leptin treatment modulates brain glucosensing function and peripheral energy metabolism of rainbow trout.
Journal: Peptides 20100601
Title: Substitution of corticosteroid with everolimus after lung transplantation: a pediatric case report.
Journal: Pharmacy world & science : PWS 20100601
Title: Pharmacokinetic and pharmacodynamic interactions between the immunosuppressant sirolimus and the lipid-lowering drug ezetimibe in healthy volunteers.
Journal: Clinical pharmacology and therapeutics 20100601
Title: PI3K/Akt and mTOR/p70S6K pathways mediate neuroprotectin D1-induced retinal pigment epithelial cell survival during oxidative stress-induced apoptosis.
Journal: Experimental eye research 20100601
Title: Sirolimus-based calcineurin inhibitor withdrawal immunosuppressive regimen in kidney transplantation: a single center experience.
Journal: Clinical and experimental nephrology 20100601
Title: Downregulation of Akt/mammalian target of rapamycin pathway in skeletal muscle is associated with increased REDD1 expression in response to chronic hypoxia.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20100601
Title: Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue.
Journal: Diabetes 20100601
Title: Benefit of early conversion from CNI-based to everolimus-based immunosuppression in heart transplantation.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20100601
Title: Rhabdomyolysis and acute kidney injury secondary to concomitant use of fluvastatin and rapamycin in a renal transplant recipient.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100601
Title: EP1 prostanoid receptor coupling to G i/o up-regulates the expression of hypoxia-inducible factor-1 alpha through activation of a phosphoinositide-3 kinase signaling pathway.
Journal: Molecular pharmacology 20100601
Title: The protein kinase CaSch9p is required for the cell growth, filamentation and virulence in the human fungal pathogen Candida albicans.
Journal: FEMS yeast research 20100601
Title: A phase I study of weekly temsirolimus and topotecan in the treatment of advanced and/or recurrent gynecologic malignancies.
Journal: Gynecologic oncology 20100601
Title: Sirolimus inhibits endogenous cholesterol synthesis induced by inflammatory stress in human vascular smooth muscle cells.
Journal: American journal of physiology. Heart and circulatory physiology 20100601
Title: Luteinizing hormone stimulates mammalian target of rapamycin signaling in bovine luteal cells via pathways independent of AKT and mitogen-activated protein kinase: modulation of glycogen synthase kinase 3 and AMP-activated protein kinase.
Journal: Endocrinology 20100601
Title: The fate of incomplete stent apposition with drug-eluting stents: an optical coherence tomography-based natural history study.
Journal: European heart journal 20100601
Title: Late progression after sirolimus-eluting stent implantation for de novo lesions--comparison with bare metal stent implantation.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20100601
Title: Does tacrolimus, in comparison with sirolimus, increase mycophenolic acid exposure in kidney transplant recipients?
Journal: Clinical pharmacology and therapeutics 20100601
Title: Mammalian target of rapamycin (mTOR) regulates cellular proliferation and tumor growth in urothelial carcinoma.
Journal: The American journal of pathology 20100601
Title: Emergent toxicities associated with the use of mTOR inhibitors in patients with advanced renal carcinoma.
Journal: Anti-cancer drugs 20100601
Title: Effects of vatalanib on tumor growth can be potentiated by mTOR blockade in vivo.
Journal: Cancer biology & therapy 20100601
Title: Rapamycin joins the aging fray: maybe Ponce de Leon visited Rapa Nui, not Florida.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20100601
Title: Randomized intervention studies in human polycystic kidney and liver disease.
Journal: Journal of the American Society of Nephrology : JASN 20100601
Title: Use of pharmacogenetics to optimize immunosuppressive therapy.
Journal: Therapeutic drug monitoring 20100601
Title: Development of a novel prohealing stent designed to deliver sirolimus from a biodegradable abluminal matrix.
Journal: Circulation. Cardiovascular interventions 20100601
Title: Everolimus plus reduced-exposure CsA versus mycophenolic acid plus standard-exposure CsA in renal-transplant recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100601
Title: Treatment of metastatic renal cell carcinoma.
Journal: Nature reviews. Urology 20100601
Title: [Treatment of adult patients with metastatic sarcoma: current shift in concepts].
Journal: Bulletin du cancer 20100601
Title: Sirolimus therapy to halt the progression of ADPKD.
Journal: Journal of the American Society of Nephrology : JASN 20100601
Title: Optic nerve tumor in tuberous sclerosis complex is not responsive to sirolimus.
Journal: Pediatric neurology 20100601
Title: Twelve-month outcomes in patients with diabetes implanted with a zotarolimus-eluting stent: results from the E-Five Registry.
Journal: Heart (British Cardiac Society) 20100601
Title: PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20100601
Title: Regulation of insulin-like growth factor-mammalian target of rapamycin signaling by microRNA in childhood adrenocortical tumors.
Journal: Cancer research 20100601
Title: A pharmacodynamic study of rapamycin in men with intermediate- to high-risk localized prostate cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100601
Title: Rapamycin reduces intrahepatic alpha-1-antitrypsin mutant Z protein polymers and liver injury in a mouse model.
Journal: Experimental biology and medicine (Maywood, N.J.) 20100601
Title: Rapamycin regulates Akt and ERK phosphorylation through mTORC1 and mTORC2 signaling pathways.
Journal: Molecular carcinogenesis 20100601
Title: Five-year long-term clinical follow-up of the XIENCE V everolimus eluting coronary stent system in the treatment of patients with de novo coronary artery lesions: the SPIRIT FIRST trial.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601
Title: Long-term follow-up of the First In Man experience with everolimus-eluting stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601
Title: Percutaneous UPLM revascularisation: the time has come.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601
Title: Procedure-related myonecrosis after bare and drug-eluting stent implantation.
Journal: Asian cardiovascular & thoracic annals 20100601
Title: Current progress in pharmacogenetics and individualized immunosuppressive drug dosing in organ transplantation.
Journal: Current opinion in molecular therapeutics 20100601
Title: The TOR pathway modulates the structure of cell walls in Arabidopsis.
Journal: The Plant cell 20100601
Title: Rapamycin can inhibit the development of Chlamydia pneumoniae, which might partly contribute to the prevention of in-stent restenosis.
Journal: Cardiovascular drugs and therapy 20100601
Title: [mTOR inhibitors].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20100601
Title: The importance of skin cancer prevention in organ transplant patients an editorial to paper by Salgo: 'switch to sirolimus in long-term renal transplant recipients: reduced premalignancies and nonmelanoma skin cancer in a controlled, prospective, randomized, blinded study'.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100601
Title: Clinical and angiographic outcomes of drug-eluting stents in patients with large vessel and single coronary artery lesion.
Journal: Clinical cardiology 20100601
Title: A randomised comparison of novolimus-eluting and zotarolimus-eluting coronary stents: 9-month follow-up results of the EXCELLA II study.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100601
Title: The twelve-month outcomes of a biolimus eluting stent with a biodegradable polymer compared with a sirolimus eluting stent with a durable polymer.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100601
Title: Coronary angioscopic findings eight months after sirolimus-eluting stent implantation: a comparison between ST-elevation myocardial infarction and stable angina pectoris.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100601
Title: Risk of diarrhoea in a long-term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8 2 variant allele.
Journal: British journal of clinical pharmacology 20100601
Title: Targeting multiple angiogenic pathways for the treatment of neuroblastoma.
Journal: Journal of pediatric surgery 20100601
Title: Comparison of the safety and efficacy of cyclosporine minimization versus cyclosporine elimination in de novo renal allograft patients receiving sirolimus.
Journal: Transplantation proceedings 20100601
Title: Rapamycin promotes the expansion of CD4(+) Foxp3(+) regulatory T cells after liver transplantation.
Journal: Transplantation proceedings 20100601
Title: Relationship between everolimus blood concentration assessed using the Innofluor Certican Fluorescence Polarization Immunoassay and the Architect i System sirolimus chemiluminescent microparticle immunoassay.
Journal: Transplantation proceedings 20100601
Title: Rapamycin inhibits activator protein-1 but not nuclear factor-kappaB activity of mature bone marrow-derived dendritic cells.
Journal: Transplantation proceedings 20100601
Title: Posttransplantation therapeutic rapamycin concentration protects nitric oxide-related vascular endothelial function: comparative effects in rat thoracic aorta and coronary endothelial cell culture.
Journal: Transplantation proceedings 20100601
Title: Long-term clinical results following stenting of the left main stem: insights from RESEARCH (Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital) and T-SEARCH (Taxus-Stent Evaluated at Rotterdam Cardiology Hospital) Registries.
Journal: JACC. Cardiovascular interventions 20100601
Title: Strut coverage and vessel wall response to zotarolimus-eluting and bare-metal stents implanted in patients with ST-segment elevation myocardial infarction: the OCTAMI (Optical Coherence Tomography in Acute Myocardial Infarction) Study.
Journal: JACC. Cardiovascular interventions 20100601
Title: A status report on drug-associated acne and acneiform eruptions.
Journal: Journal of drugs in dermatology : JDD 20100601
Title: The phosphatidylinositol 3-kinase/Akt/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients.
Journal: Oncotarget 20100601
Title: mTOR-mediated activation of p70 S6K induces differentiation of pluripotent human embryonic stem cells.
Journal: Cellular reprogramming 20100601
Title: Hyperglycemia induced by tacrolimus and sirolimus is reversible in normal sprague-dawley rats.
Journal: Endocrine 20100601
Title: Autism spectrum disorder is related to endoplasmic reticulum stress induced by mutations in the synaptic cell adhesion molecule, CADM1.
Journal: Cell death & disease 20100601
Title: Initial experience with an everolimus-eluting, second-generation drug-eluting stent for treatment of intracranial atherosclerosis.
Journal: Journal of neurointerventional surgery 20100601
Title: Involvement of heterogeneous ribonucleoprotein F in the regulation of cell proliferation via the mammalian target of rapamycin/S6 kinase 2 pathway.
Journal: The Journal of biological chemistry 20100528
Title: mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs.
Journal: Science (New York, N.Y.) 20100528
Title: Thrombotic microangiopathy after GVHD prophylaxis with tacrolimus/sirolimus: a call for use of consensus definition in reporting.
Journal: Blood 20100527
Title: Late airway anastomotic dehiscence associated with sirolimus and migratory staples in a lung transplant recipient.
Journal: Transplantation 20100527
Title: Smooth muscle cells orchestrate the endothelial cell response to flow and injury.
Journal: Circulation 20100525
Title: Phosphatidic acid is a leukocyte chemoattractant that acts through S6 kinase signaling.
Journal: The Journal of biological chemistry 20100521
Title: FOXO3a regulates glycolysis via transcriptional control of tumor suppressor TSC1.
Journal: The Journal of biological chemistry 20100521
Title: [18F]Fluorodeoxyglucose positron emission tomography for outcome prediction of mammalian target of rapamycin inhibitor therapy.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100520
Title: Rapamycin and quasi-programmed aging: four years later.
Journal: Cell cycle (Georgetown, Tex.) 20100515
Title: Conversion to sirolimus in African American renal allograft recipients undergoing early steroid withdrawal: intermediate-term risks and benefits.
Journal: Transplantation 20100515
Title: Long-term vascular changes after drug-eluting stent implantation assessed by serial volumetric intravascular ultrasound analysis.
Journal: The American journal of cardiology 20100515
Title: Quality of life in patients with advanced renal cell carcinoma treated with temsirolimus or interferon-alpha.
Journal: British journal of cancer 20100511
Title: Single amino-acid changes that confer constitutive activation of mTOR are discovered in human cancer.
Journal: Oncogene 20100506
Title: Everolimus-eluting versus paclitaxel-eluting stents in coronary artery disease.
Journal: The New England journal of medicine 20100506
Title: Second-generation drug-eluting coronary stents.
Journal: The New England journal of medicine 20100506
Title: Mammalian target of rapamycin signaling modulates photic entrainment of the suprachiasmatic circadian clock.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100505
Title: Everolimus and pazopanib: two new drugs for renal cell cancer.
Journal: The Medical letter on drugs and therapeutics 20100503
Title: Late stent malapposition risk is higher after drug-eluting stent compared with bare-metal stent implantation and associates with late stent thrombosis.
Journal: European heart journal 20100501
Title: mTOR inhibitor RAD001 (Everolimus) enhances the effects of imatinib in chronic myeloid leukemia by raising the nuclear expression of c-ABL protein.
Journal: Leukemia research 20100501
Title: Combined treatment with cisplatin and sirolimus to enhance cell death in human mesothelioma.
Journal: The Journal of thoracic and cardiovascular surgery 20100501
Title: Sirolimus and everolimus clearance in maintenance kidney and liver transplant recipients: diagnostic efficiency of the concentration/dose ratio for the prediction of trough steady-state concentrations.
Journal: Upsala journal of medical sciences 20100501
Title: Effects of the novel protein kinase C inhibitor AEB071 (Sotrastaurin) on rat cardiac allograft survival using single agent treatment or combination therapy with cyclosporine, everolimus or FTY720.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100501
Title: Identification of functional FKB protein in Echinococcus granulosus: its involvement in the protoscolicidal action of rapamycin derivates and in calcium homeostasis.
Journal: International journal for parasitology 20100501
Title: Intrarenal vascular resistance parameters in kidney transplant patients receiving calcineurin inhibitor-based or sirolimus-based regimens.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100501
Title: Anaemia, microcytosis and sirolimus--is iron the missing link?
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100501
Title: Methylglyoxal activates Gcn2 to phosphorylate eIF2alpha independently of the TOR pathway in Saccharomyces cerevisiae.
Journal: Applied microbiology and biotechnology 20100501
Title: IVUS radiofrequency analysis in the evaluation of the polymeric struts of the bioabsorbable everolimus-eluting device during the bioabsorption process.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100501
Title: Randomized comparison of everolimus- and paclitaxel-eluting stents: pooled analysis of the 2-year clinical follow-up from the SPIRIT II and III trials.
Journal: European heart journal 20100501
Title: Mammalian target of rapamycin regulates vascular endothelial growth factor-dependent liver cyst growth in polycystin-2-defective mice.
Journal: Hepatology (Baltimore, Md.) 20100501
Title: Histology of highly echolucent regions in optical coherence tomography images from two patients with sirolimus-eluting stent restenosis.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100501
Title: Sirolimus versus paclitaxel-eluting stents in small coronary vessels: long-term outcomes from a single-center registry.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20100501
Title: Regulation of the autophagic machinery in human neutrophils.
Journal: European journal of immunology 20100501
Title: Therapies for the medical management of persistent hypoglycaemia in two cases of inoperable malignant insulinoma.
Journal: European journal of endocrinology 20100501
Title: The treatment of recurrent/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL) with everolimus results in clinical responses and mobilization of CLL cells into the circulation.
Journal: Cancer 20100501
Title: Delayed re-endothelialization with rapamycin-coated stents is rescued by the addition of a glycogen synthase kinase-3beta inhibitor.
Journal: Cardiovascular research 20100501
Title: In vitro and in vivo performance of a dual drug-eluting stent (DDES).
Journal: Biomaterials 20100501
Title: Exendin-4 protects pancreatic beta cells from the cytotoxic effect of rapamycin by inhibiting JNK and p38 phosphorylation.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20100501
Title: Indications, tolerance and complications of a sirolimus and calcineurin inhibitor immunosuppression regimen: intermediate experience in pediatric heart transplantation recipients.
Journal: Pediatric transplantation 20100501
Title: Treatment with the mTOR inhibitor temsirolimus in patients with malignant PEComa.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20100501
Title: Comparison by optical coherence tomography of paclitaxel-eluting stents with sirolimus-eluting stents implanted in one coronary artery in one procedure. - 6-month follow-up -.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20100501
Title: Natural products in structure-assisted design of molecular cancer therapeutics.
Journal: Current pharmaceutical design 20100501
Title: A Phase II trial of the oral mTOR inhibitor everolimus in relapsed Hodgkin lymphoma.
Journal: American journal of hematology 20100501
Title: MCF-7 breast cancer cells selected for tamoxifen resistance acquire new phenotypes differing in DNA content, phospho-HER2 and PAX2 expression, and rapamycin sensitivity.
Journal: Cancer biology & therapy 20100501
Title: Papillary renal cell carcinoma with cutaneous metastases.
Journal: The American journal of the medical sciences 20100501
Title: Impact of angiographic and intravascular ultrasound features on clinical outcome after sirolimus-eluting stent implantation for de-novo lesions in nondiabetic and type 2 diabetic patients.
Journal: Coronary artery disease 20100501
Title: Transforming growth factor beta 1 (TGF-beta1) and rapamycin synergize to effectively suppress human T cell responses via upregulation of FoxP3+ Tregs.
Journal: Transplant immunology 20100501
Title: Giant warts in a kidney transplant patient: regression with sirolimus.
Journal: The British journal of dermatology 20100501
Title: Personalized molecular targeted therapy in advanced, recurrent hepatocellular carcinoma after liver transplantation: a proof of principle.
Journal: Journal of hepatology 20100501
Title: Predictor of subsequent target lesion revascularization in patients with drug-eluting stent restenosis undergoing percutaneous coronary intervention.
Journal: Journal of cardiology 20100501
Title: Rapamycin extends maximal lifespan in cancer-prone mice.
Journal: The American journal of pathology 20100501
Title: How to interpret phase II data for everolimus plus bevacizumab in renal cell carcinoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100501
Title: Phase II trial of bevacizumab and everolimus in patients with advanced renal cell carcinoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100501
Title: The initial extent of malapposition in ST-elevation myocardial infarction treated with drug-eluting stent: the usefulness of optical coherence tomography.
Journal: Yonsei medical journal 20100501
Title: Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.
Journal: Nature neuroscience 20100501
Title: Mutant protein kinase C gamma that causes spinocerebellar ataxia type 14 (SCA14) is selectively degraded by autophagy.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20100501
Title: A functional link between polo-like kinase 1 and the mammalian target-of-rapamycin pathway?
Journal: Cell cycle (Georgetown, Tex.) 20100501
Title: Preferential increase in memory and regulatory subsets during T-lymphocyte immune reconstitution after Thymoglobulin induction therapy with maintenance sirolimus vs cyclosporine.
Journal: Transplant immunology 20100501
Title: Calcineurin inhibitor-related cholestasis complicating lung transplantation.
Journal: The Annals of thoracic surgery 20100501
Title: Novel immunosuppressive agents in kidney transplantation.
Journal: Clinical nephrology 20100501
Title: Addition of induction therapy offsets the hazard of marked calcineurin minimization among renal transplant recipients treated with sirolimus.
Journal: Clinical nephrology 20100501
Title: True comparison of different stents in the same coronary artery.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20100501
Title: Vascular response to overlapping everolimus-eluting stents. - Comparison with paclitaxel-eluting stents -.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20100501
Title: Everolimus in relapsed Hodgkin's lymphoma: something exciting or a case of caveat mTOR?
Journal: American journal of hematology 20100501
Title: High incidence of thrombus formation at 18 months after paclitaxel-eluting stent implantation: angioscopic comparison with sirolimus-eluting stent.
Journal: American heart journal 20100501
Title: Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy.
Journal: Cell cycle (Georgetown, Tex.) 20100501
Title: Long-interval T2-weighted subtraction magnetic resonance imaging: a powerful new outcome measure in multiple sclerosis trials.
Journal: Annals of neurology 20100501
Title: Longer-term outcomes of paclitaxel stent implantation as an initial treatment strategy for sirolimus-eluting stent restenosis.
Journal: The Journal of invasive cardiology 20100501
Title: Sirolimus and tuberous sclerosis-associated renal angiomyolipomas.
Journal: Archives of disease in childhood 20100501
Title: [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma].
Journal: Aktuelle Urologie 20100501
Title: [Gingival hyperplasia secondary to everolimus therapy].
Journal: Actas dermo-sifiliograficas 20100501
Title: Paclitaxel- versus sirolimus-eluting stents for treatment of ST-segment elevation myocardial infarction: with analyses for diabetic and nondiabetic subpopulation.
Journal: JACC. Cardiovascular interventions 20100501
Title: Optical coherence tomography assessment of in vivo vascular response after implantation of overlapping bare-metal and drug-eluting stents.
Journal: JACC. Cardiovascular interventions 20100501
Title: 10-year follow-up of the first Cypher stent implanted in human: an invasive evaluation with angiography, intravascular ultrasound, and optical coherence tomography.
Journal: JACC. Cardiovascular interventions 20100501
Title: Calorie restriction: what recent results suggest for the future of ageing research.
Journal: European journal of clinical investigation 20100501
Title: Immunosuppressive agents and bone disease in renal transplant patients with hypercalcemia.
Journal: Transplantation proceedings 20100501
Title: De novo everolimus-based therapy in renal transplant recipients: effect on proteinuria and renal prognosis.
Journal: Transplantation proceedings 20100501
Title: Once-a-day administration of everolimus, cyclosporine, and steroid after renal transplantation: a review of the rationale.
Journal: Transplantation proceedings 20100501
Title: Once daily everolimus is safe and effective in de novo renal transplant recipients: six-month results of a pilot study.
Journal: Transplantation proceedings 20100501
Title: Conversion of stable kidney transplant recipients from a twice-daily to once-daily everolimus regimen.
Journal: Transplantation proceedings 20100501
Title: Conversion to rapamycin immunosuppression for malignancy after kidney transplantation.
Journal: Transplantation proceedings 20100501
Title: Effects of sirolimus on human mesangial cells.
Journal: Transplantation proceedings 20100501
Title: Liver transplantation due to iatrogenic injuries: two case reports.
Journal: Transplantation proceedings 20100501
Title: Liver resection associated with mini porto-caval shunt as salvage treatment in patients with progression of hepatocellular carcinoma before liver transplantation: a case report.
Journal: Transplantation proceedings 20100501
Title: Lower homocysteine levels in renal transplant recipients treated with everolimus: a possible link with a decreased cardiovascular risk?
Journal: Transplantation proceedings 20100501
Title: Eighteen-month clinical safety and efficacy outcomes of sirolimus-, paclitaxel- and zotarolimus-drug eluting stents in diabetic patients undergoing percutaneous coronary intervention for complex coronary artery stenosis.
Journal: Annals of the Academy of Medicine, Singapore 20100501
Title: The role of mTOR in memory CD8 T-cell differentiation.
Journal: Immunological reviews 20100501
Title: A randomised comparison between everolimus-eluting stent and sirolimus-eluting stent in chronic coronary total occlusions. Rationale and design of the CIBELES (non-acute Coronary occlusion treated by EveroLimus-Eluting Stent) trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100501
Title: Endothelial function rather than endothelial restoration is altered in paclitaxel- as compared to bare metal-, sirolimusand tacrolimus-eluting stents.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100501
Title: Neuroendocrine gastroenteropancreatic tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20100501
Title: Present state of target therapy for disseminated renal cell carcinoma.
Journal: Immunotherapy 20100501
Title: Regulation of survivin by PI3K/Akt/p70S6K1 pathway.
Journal: Biochemical and biophysical research communications 20100430
Title: mTOR inhibitor rapamycin alone or combined with cisplatin inhibits growth of esophageal squamous cell carcinoma in nude mice.
Journal: Cancer letters 20100428
Title: Impact of immunosuppressants on the therapeutic efficacy of in vitro-expanded CD4+CD25+Foxp3+ regulatory T cells in allotransplantation.
Journal: Transplantation 20100427
Title: Interaction between everolimus and tacrolimus in renal transplant recipients: a pharmacokinetic controlled trial.
Journal: Transplantation 20100427
Title: Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments.
Journal: The Journal of biological chemistry 20100423
Title: Sirolimus- versus paclitaxel-eluting stents for the treatment of coronary bifurcations results: from the COBIS (Coronary Bifurcation Stenting) Registry.
Journal: Journal of the American College of Cardiology 20100420
Title: Rapamycin regulates endothelial cell migration through regulation of the cyclin-dependent kinase inhibitor p27Kip1.
Journal: The Journal of biological chemistry 20100416
Title: Ribosomal protein S6 kinase is a critical downstream effector of the target of rapamycin complex 1 for long-term facilitation in Aplysia.
Journal: The Journal of biological chemistry 20100416
Title: Long-term follow-up of patients with sirolimus-eluting stents for treatment of bare-metal in-stent restenosis.
Journal: International journal of cardiology 20100415
Title: Long-term outcome after drug eluting stenting in patients with ST-segment elevation myocardial infarction: data from the REAL registry.
Journal: International journal of cardiology 20100415
Title: Everolimus with reduced calcineurin inhibitor in thoracic transplant recipients with renal dysfunction: a multicenter, randomized trial.
Journal: Transplantation 20100415
Title: Sensitive quantification of sirolimus and everolimus by LC-MS/MS with online sample cleanup.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100415
Title: Comparison by meta-analysis of drug-eluting stents and bare metal stents for saphenous vein graft intervention.
Journal: The American journal of cardiology 20100415
Title: Multicenter phase II study of everolimus in patients with previously treated metastatic gastric cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100410
Title: Late and very late stent thrombosis after polymer-based sirolimus- or paclitaxel-eluting stent implantation in real-world clinical practice.
Journal: Chinese medical journal 20100405
Title: Gender difference in patients with acute myocardial infarction treated by primary percutaneous coronary intervention in drug-eluting stent era.
Journal: Chinese medical journal 20100405
Title: Absence of gender disparity in short-term clinical outcomes in patients with acute ST-segment elevation myocardial infarction undergoing sirolimus-eluting stent based primary coronary intervention: a report from Shanghai Acute Coronary Event (SACE) Registry.
Journal: Chinese medical journal 20100405
Title: Comparison of long-term clinical outcome after successful implantation of Firebird sirolimus- and Taxus paclitaxel-eluting stents in Chinese population: analysis of a large single center registry.
Journal: Chinese medical journal 20100405
Title: CD4+Foxp3+ regulatory T cells converted by rapamycin from peripheral CD4+CD25(-) naive T cells display more potent regulatory ability in vitro.
Journal: Chinese medical journal 20100405
Title: Everolimus-eluting versus paclitaxel-eluting stents.
Journal: Lancet (London, England) 20100403
Title: Everolimus-eluting versus paclitaxel-eluting stents.
Journal: Lancet (London, England) 20100403
Title: The autophagy-lysosome pathway: a novel mechanism involved in the processing of oxidized LDL in human vascular endothelial cells.
Journal: Biochemical and biophysical research communications 20100402
Title: Treatment of vertebral artery origin stenosis with anti-proliferative drug-eluting stents.
Journal: Journal of neuroimaging : official journal of the American Society of Neuroimaging 20100401
Title: Fracture of a paclitaxol-eluting stent implanted for in-stent restenosis at the site of sirolimus-eluting stent fracture.
Journal: International journal of cardiology 20100401
Title: Death caused by simultaneous subacute stent thrombosis of sirolimus-eluting stents in left anterior descending artery and left circumflex artery.
Journal: International journal of cardiology 20100401
Title: Rapamycin inhibits proliferation and migration of hepatoma cells in vitro.
Journal: The Journal of surgical research 20100401
Title: Rapamycin promotes the osteoblastic differentiation of human embryonic stem cells by blocking the mTOR pathway and stimulating the BMP/Smad pathway.
Journal: Stem cells and development 20100401
Title: Involvement of mTOR and survivin inhibition in tamoxifen-induced apoptosis in human hepatoblastoma cell line HepG2.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100401
Title: Increase in proteinuria >200 mg/g after late rejection is associated with poor graft survival.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100401
Title: Impact of Cyclin B2 and Cell division cycle 2 on tubular hyperplasia in progressive chronic renal failure rats.
Journal: American journal of physiology. Renal physiology 20100401
Title: Tuberous sclerosis complex: a brave new world?
Journal: Current opinion in neurology 20100401
Title: A clinical and angiographic study of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with multivessel coronary artery disease. Study design and rationale of the EXECUTIVE trial.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20100401
Title: Activation of mTOR signaling pathway contributes to survival of cervical cancer cells.
Journal: Gynecologic oncology 20100401
Title: Targeting of VEGF-dependent transendothelial migration of cancer cells by bevacizumab.
Journal: Molecular oncology 20100401
Title: Inhibition of target of rapamycin signaling and stress activate autophagy in Chlamydomonas reinhardtii.
Journal: Plant physiology 20100401
Title: Implication of RICTOR in the mTOR inhibitor-mediated induction of insulin-like growth factor-I receptor (IGF-IR) and human epidermal growth factor receptor-2 (Her2) expression in gastrointestinal cancer cells.
Journal: Biochimica et biophysica acta 20100401
Title: In vitro interaction of posaconazole with calcineurin inhibitors and sirolimus against zygomycetes.
Journal: The Journal of antimicrobial chemotherapy 20100401
Title: Inhibition of glycolysis enhances cisplatin-induced apoptosis in ovarian cancer cells.
Journal: American journal of obstetrics and gynecology 20100401
Title: A 3-year clinical outcome after percutaneous coronary intervention using sirolimus-eluting stent and off-pump coronary artery bypass grafting for the treatment of diabetic patients with multivessel disease.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20100401
Title: Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: an in vivo bioluminescence imaging study.
Journal: European journal of cancer (Oxford, England : 1990) 20100401
Title: Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective effect of rapamycin in neonatal hypoxia-ischemia.
Journal: Autophagy 20100401
Title: Sirolimus-based immunosuppression is associated with increased survival after liver transplantation for hepatocellular carcinoma.
Journal: Hepatology (Baltimore, Md.) 20100401
Title: 4-Substituted-7-azaindoles bearing a ureidobenzofuranone moiety as potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR).
Journal: Bioorganic & medicinal chemistry letters 20100401
Title: New drug-eluting stent concepts.
Journal: Nature reviews. Cardiology 20100401
Title: Long-term clinical outcome of chronic total occlusive lesions treated with drug-eluting stents: comparison of sirolimus-eluting and paclitaxel-eluting stents.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20100401
Title: RAD001 offers a therapeutic intervention through inhibition of mTOR as a potential strategy for esophageal cancer.
Journal: Oncology reports 20100401
Title: Relevance of the mTOR signaling pathway in the pathophysiology of splenomegaly in rats with chronic portal hypertension.
Journal: Journal of hepatology 20100401
Title: mTOR signaling and drug development in cancer.
Journal: Nature reviews. Clinical oncology 20100401
Title: Real world, long-term outcomes comparison between paclitaxel-eluting and sirolimus-eluting stent platforms.
Journal: Journal of interventional cardiology 20100401
Title: Two-year clinical registry follow-up of endothelial progenitor cell capture stent versus sirolimus-eluting bioabsorbable polymer-coated stent versus bare metal stents in patients undergoing primary percutaneous coronary intervention for ST elevation myocardial infarction.
Journal: Journal of interventional cardiology 20100401
Title: Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20100401
Title: FDA approval summary: temsirolimus as treatment for advanced renal cell carcinoma.
Journal: The oncologist 20100401
Title: Periadventitial rapamycin-eluting microbeads promote vein graft disease in long-term pig vein-into-artery interposition grafts.
Journal: Circulation. Cardiovascular interventions 20100401
Title: In-hospital and 12-month postprocedural clinical outcome of coronary bifurcational lesion treatment with the endeavor stent.
Journal: Journal of interventional cardiology 20100401
Title: Drug-eluting stents versus bare-metal stents in acute ST-segment elevation myocardial infarction. a single-center experience with long-term follow up.
Journal: The Journal of invasive cardiology 20100401
Title: Drug-eluting stent versus bare-metal stent in acute ST-segment elevation myocardial infarction: a word of caution.
Journal: The Journal of invasive cardiology 20100401
Title: Percutaneous interventions below the knee in patients with critical limb ischemia using drug eluting stents.
Journal: The Journal of cardiovascular surgery 20100401
Title: Drug eluting stents versus PTA with GP IIb/IIIa blockade below the knee in patients with current ulcers--The BELOW Study.
Journal: The Journal of cardiovascular surgery 20100401
Title: Missing data in repeated measures study.
Journal: Heart (British Cardiac Society) 20100401
Title: Increased restenosis rates 12 months after coronary implantation of the sirolimus-eluting YUKON-choice stent compared to the paclitaxel-eluting TAXUS Stent.
Journal: Clinical cardiology 20100401
Title: Thrombus in sirolimus-eluting stent identified by optical coherence tomography.
Journal: Clinical cardiology 20100401
Title: Palliative chemotherapy for pancreatic malignancies.
Journal: The Surgical clinics of North America 20100401
Title: Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.
Journal: Molecular cancer therapeutics 20100401
Title: Evaluation of a rapamycin-regulated serotype 2 adeno-associated viral vector in macaque parotid glands.
Journal: Oral diseases 20100401
Title: Sirolimus- versus paclitaxel-eluting stents for the treatment of cardiac allograft vasculopathy.
Journal: JACC. Cardiovascular interventions 20100401
Title: Monitoring in vivo absorption of a drug-eluting bioabsorbable stent with intravascular ultrasound-derived parameters a feasibility study.
Journal: JACC. Cardiovascular interventions 20100401
Title: Catheter-induced stent occlusion: uncommon complication during diagnostic angiography.
Journal: JACC. Cardiovascular interventions 20100401
Title: Polymer-free biolimus a9-coated stent demonstrates more sustained intimal inhibition, improved healing, and reduced inflammation compared with a polymer-coated sirolimus-eluting cypher stent in a porcine model.
Journal: Circulation. Cardiovascular interventions 20100401
Title: A case of lipid core plaque progression and rupture at the edge of a coronary stent: elucidating the mechanisms of drug-eluting stent failure.
Journal: Circulation. Cardiovascular interventions 20100401
Title: [Effect of rapamycin on apoptosis in human myelodysplastic syndrome cell line MUTZ-1 and its possible mechanisms].
Journal: Zhongguo shi yan xue ye xue za zhi 20100401
Title: Can cyclosporine blood level be reduced to half after heart transplantation?
Journal: Transplantation proceedings 20100401
Title: Combined sirolimus-calcineurin inhibitor immunosuppressive therapy in simultaneous heart and kidney transplantation: a retrospective analysis of a single hospital's experience.
Journal: Transplantation proceedings 20100401
Title: The survival of heart transplant recipients using cyclosporine and everolimus is not inferior to that using cyclosporine and mycophenolate.
Journal: Transplantation proceedings 20100401
Title: Sunitinib, sorafenib, temsirolimus or bevacizumab in the treatment of metastatic renal cell carcinoma: a review of health economic evaluations.
Journal: Journal of chemotherapy (Florence, Italy) 20100401
Title: [Mammalian target of rapamycin inhibitors for the targeted therapy of non-small cell lung cancer].
Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20100401
Title: [Neuroendocrine carcinoma of the lung: a diagnostic and therapeutic challenge].
Journal: Medizinische Klinik (Munich, Germany : 1983) 20100401
Title: Effect and mechanism of panaxoside Rg1 on neovascularization in myocardial infarction rats.
Journal: Chinese journal of integrative medicine 20100401
Title: Stem cell marker upregulation in normal cutaneous vessels following pulsed-dye laser exposure and its abrogation by concurrent rapamycin administration: implications for treatment of port-wine stain birthmarks.
Journal: Journal of cutaneous pathology 20100401
Title: [Everolimus (RAD001/Afinitor) in the treatment of metastatic cell carcinoma].
Journal: Revue medicale de Liege 20100401
Title: Paclitaxel and sirolimus eluting stents versus bare metal stents: long-term risk of stent thrombosis and other outcomes. From the Western Denmark Heart Registry.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100401
Title: In vivo evaluation of stent strut distribution patterns in the bioabsorbable everolimus-eluting device: an OCT ad hoc analysis of the revision 1.0 and revision 1.1 stent design in the ABSORB clinical trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100401
Title: Short- and long-term health related quality-of-life and anginal status of the Arterial Revascularisation Therapies Study part II, ARTS-II; sirolimus-eluting stents for the treatment of patients with multivessel coronary artery disease.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100401
Title: Identification of annexin A13 as a regulator of chemotherapy resistance using random homozygous gene perturbation.
Journal: Analytical and quantitative cytology and histology 20100401
Title: [Effect of sirolimus on capacity of splenic dendritic cells from traumatized mice in inducing T cell responses ex vivo].
Journal: Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20100401
Title: Rapamycin inhibits relapsing experimental autoimmune encephalomyelitis by both effector and regulatory T cells modulation.
Journal: Journal of neuroimmunology 20100330
Title: First report on a series of HIV patients undergoing rapamycin monotherapy after liver transplantation.
Journal: Transplantation 20100327
Title: Comparing an early corticosteroid/late calcineurin-free immunosuppression protocol to a sirolimus-, cyclosporine A-, and prednisone-based regimen for pancreas-kidney transplantation.
Journal: Transplantation 20100327
Title: Efficacy and safety of zotarolimus-eluting and sirolimus-eluting coronary stents in routine clinical care (SORT OUT III): a randomised controlled superiority trial.
Journal: Lancet (London, England) 20100327
Title: Sorting out drug-eluting stents.
Journal: Lancet (London, England) 20100327
Title: Bafilomycins produced in culture by Streptomyces spp. isolated from marine habitats are potent inhibitors of autophagy.
Journal: Journal of natural products 20100326
Title: Letter by Virmani et al regarding article, 'Drug-eluting stents in animals and patients: where do we stand today?'.
Journal: Circulation 20100323
Title: An expeditious route to fluorinated rapamycin analogues by utilising mutasynthesis.
Journal: Chembiochem : a European journal of chemical biology 20100322
Title: Lesion complexity determines arterial drug distribution after local drug delivery.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20100319
Title: Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation.
Journal: Oncogene 20100318
Title: TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity.
Journal: Oncogene 20100318
Title: 5-year clinical outcomes of the ARTS II (Arterial Revascularization Therapies Study II) of the sirolimus-eluting stent in the treatment of patients with multivessel de novo coronary artery lesions.
Journal: Journal of the American College of Cardiology 20100316
Title: Immunosuppressant neurotoxicity in rat brain models: oxidative stress and cellular metabolism.
Journal: Chemical research in toxicology 20100315
Title: Comparison of outcomes between Zotarolimus- and sirolimus-eluting stents in patients with ST-segment elevation acute myocardial infarction.
Journal: The American journal of cardiology 20100315
Title: Rapamycin for Kaposi's sarcoma and graft-versus-host disease in bone marrow transplant recipient.
Journal: Transplantation 20100315
Title: Pregnancy restores the regenerative capacity of the aged liver via activation of an mTORC1-controlled hyperplasia/hypertrophy switch.
Journal: Genes & development 20100315
Title: mTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of action.
Journal: The Journal of biological chemistry 20100312
Title: Rapamycin inhibits oncogenic intestinal ion channels and neoplasia in APC(Min/+) mice.
Journal: Oncogene 20100311
Title: Stem-cell transplantation for sickle cell disease.
Journal: The New England journal of medicine 20100311
Title: Phase II trial of the oral mammalian target of rapamycin inhibitor everolimus in relapsed or refractory Waldenstrom macroglobulinemia.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100310
Title: Nocardiopsins: new FKBP12-binding macrolide polyketides from an Australian marine-derived actinomycete, Nocardiopsis sp.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20100308
Title: Neuroendocrine tumors of the pancreas: what's new. Highlights from the '2010 ASCO Gastrointestinal Cancers Symposium'. Orlando, FL, USA. January 22-24, 2010.
Journal: JOP : Journal of the pancreas 20100305
Title: Liquid chromatography-tandem mass spectrometry method for determination of Sirolimus coated drug eluting nano porous carbon stents.
Journal: Biomedical chromatography : BMC 20100301
Title: Rapamycin potentiates the effects of paclitaxel in endometrial cancer cells through inhibition of cell proliferation and induction of apoptosis.
Journal: International journal of cancer 20100301
Title: Comparative pharmacokinetics of RAD001 (everolimus) in normal and tumor-bearing rodents.
Journal: Cancer chemotherapy and pharmacology 20100301
Title: Increased frequency of regulatory T cells and selection of highly potent CD62L+ cells during treatment of human lung transplant recipients with rapamycin.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100301
Title: Sirolimus monotherapy as maintenance immunosuppression: a multicenter experience.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100301
Title: Rapamycin (sirolimus) in tuberous sclerosis associated pediatric central nervous system tumors.
Journal: Pediatric blood & cancer 20100301
Title: Rapamycin, unlike cyclosporine A, enhances suppressive functions of in vitro-induced CD4+CD25+ Tregs.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100301
Title: Autophagy is involved in starvation response and cell death in Blastocystis.
Journal: Microbiology (Reading, England) 20100301
Title: [Impact of immunotherapy in metastatic kidney cancer in Germany after introduction of new target therapy--results of a telephone survey of the German Society of Immuno- and Targeted Therapy (DGFIT)].
Journal: Aktuelle Urologie 20100301
Title: Rapamycin and the transcription factor C/EBPbeta as a switch in osteoclast differentiation: implications for lytic bone diseases.
Journal: Journal of molecular medicine (Berlin, Germany) 20100301
Title: Sirolimus and cyclosporine A alter barrier function in renal proximal tubular cells through stimulation of ERK1/2 signaling and claudin-1 expression.
Journal: American journal of physiology. Renal physiology 20100301
Title: Dissecting the role of mTOR: lessons from mTOR inhibitors.
Journal: Biochimica et biophysica acta 20100301
Title: Cytocidal amino acid starvation of Saccharomyces cerevisiae and Candida albicans acetolactate synthase (ilv2{Delta}) mutants is influenced by the carbon source and rapamycin.
Journal: Microbiology (Reading, England) 20100301
Title: Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1.
Journal: Journal of the American Society of Nephrology : JASN 20100301
Title: AZD6244 (ARRY-142886) enhances the antitumor activity of rapamycin in mouse models of human hepatocellular carcinoma.
Journal: Cancer 20100301
Title: The release kinetics of drug eluting stents containing sirolimus as coated drug: role of release media.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100301
Title: Fission yeast TORC1 regulates phosphorylation of ribosomal S6 proteins in response to nutrients and its activity is inhibited by rapamycin.
Journal: Journal of cell science 20100301
Title: Bioequivalence testing of immunosuppressants: concepts and misconceptions.
Journal: Kidney international. Supplement 20100301
Title: Effects of aging and gender on muscle mass and regulation of Akt-mTOR-p70s6k related signaling in the F344BN rat model.
Journal: Mechanisms of ageing and development 20100301
Title: Simulation of sirolimus exposures and population variability immediately post renal transplantation: importance of the patient's CYP3A5 genotype in tailoring treatment.
Journal: Biopharmaceutics & drug disposition 20100301
Title: Protection from rapamycin-induced apoptosis by insulin-like growth factor-I is partially dependent on protein kinase C signaling.
Journal: Cancer research 20100301
Title: Everolimus.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100301
Title: Recent advances and future directions in the management of metastatic renal cell carcinoma.
Journal: Anti-cancer agents in medicinal chemistry 20100301
Title: Restenosis rates following vertebral artery origin stenting: does stent type make a difference?
Journal: The Journal of invasive cardiology 20100301
Title: Conversion of cyclosporine to sirolimus before 12 months is associated with marked improvement in renal function and low proteinuria in a South African renal transplant population.
Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20100301
Title: [Recent progress in the molecular-targeting treatment of neuroendocrine tumors].
Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20100301
Title: Molecular basis of different outcomes for drug-eluting stents that release sirolimus or tacrolimus.
Journal: Current opinion in drug discovery & development 20100301
Title: Treatment of non-left main bifurcation lesions using the sirolimus-eluting stent: A comparison of chronic outcomes of cross-over single stenting and crush stenting.
Journal: Journal of cardiology 20100301
Title: Rapamycin and tacrolimus differentially modulate acute graft-versus-host disease in rats after liver transplantation.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20100301
Title: Does 'late catch-up' exist in drug-eluting stents: insights from a serial quantitative coronary angiography analysis of sirolimus versus paclitaxel-eluting stents.
Journal: American heart journal 20100301
Title: Long-term outcome of percutaneous catheter intervention for de novo coronary bifurcation lesions with drug-eluting stents or bare-metal stents.
Journal: American heart journal 20100301
Title: Everolimus (RAD001) in the treatment of advanced renal cell carcinoma: a review.
Journal: The oncologist 20100301
Title: Treatment strategies and clinical trial design in ADPKD.
Journal: Advances in chronic kidney disease 20100301
Title: Predictive value of C-reactive protein after drug-eluting stent implantation.
Journal: Future cardiology 20100301
Title: Use of tacrolimus and the development of posttransplant diabetes mellitus: a Brazilian single-center, observational study.
Journal: Transplantation proceedings 20100301
Title: Recovery of renal function in heart transplantation patients after conversion from a calcineurin inhibitor-based therapy to sirolimus.
Journal: Transplantation proceedings 20100301
Title: Cell phenotype evaluation at various sites after skin transplantation and FTY720 plus sirolimus therapy.
Journal: Transplantation proceedings 20100301
Title: Sirolimus in combination with FTY720: analysis of urinary and serum parameters.
Journal: Transplantation proceedings 20100301
Title: Rescue immunosuppression with mammalian target of rapamycin inhibitor drugs in liver transplantation.
Journal: Transplantation proceedings 20100301
Title: mTOR signaling: a central pathway to pathogenesis in systemic lupus erythematosus?
Journal: Discovery medicine 20100301
Title: Long-term clinical outcomes after sirolimus-eluting stent implantation in dialysis patients.
Journal: International heart journal 20100301
Title: Rapamycin-mediated FOXO1 inactivation reduces the anticancer efficacy of rapamycin.
Journal: Anticancer research 20100301
Title: [Recent advance in tuberous sclerosis-related genes and their expression].
Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology 20100301
Title: [Vessel response evaluation by optical coherence tomography after drug-eluting stent implantation in the left main coronary artery].
Journal: Giornale italiano di cardiologia (2006) 20100301
Title: Sirolimus-induced severe hypertriglyceridemia in a lung transplant recipient.
Journal: Transplantation 20100227
Title: StatBite: FDA oncology drug product approvals in 2009.
Journal: Journal of the National Cancer Institute 20100224
Title: Maintenance of long-term clinical benefit with sirolimus-eluting stents in patients with ST-segment elevation myocardial infarction 3-year results of the SESAMI (sirolimus-eluting stent versus bare-metal stent in acute myocardial infarction) trial.
Journal: Journal of the American College of Cardiology 20100223
Title: Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice.
Journal: Blood 20100218
Title: Rapid inactivation of proteins by rapamycin-induced rerouting to mitochondria.
Journal: Developmental cell 20100216
Title: Long-term effectiveness and safety of sirolimus stent implantation for coronary in-stent restenosis results of the TRUE (Tuscany Registry of sirolimus for unselected in-stent restenosis) registry at 4 years.
Journal: Journal of the American College of Cardiology 20100216
Title: Three-year outcome of drug-eluting stent implantation for coronary artery bifurcation lesions.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100215
Title: Comparison of 2-year clinical outcomes with sirolimus and paclitaxel-eluting stents for patients with diabetes: results of the Registro Regionale AngiopLastiche Emilia-Romagna Registry.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100215
Title: Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube.
Journal: Developmental biology 20100215
Title: Systemic rapamycin without loading dose for restenosis prevention after coronary bare metal stent implantation.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100215
Title: Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy.
Journal: Cancer research 20100215
Title: Supplemental islet infusions restore insulin independence after graft dysfunction in islet transplant recipients.
Journal: Transplantation 20100215
Title: The impact of body mass index on the one year outcomes of patients treated by percutaneous coronary intervention with Biolimus- and Sirolimus-eluting stents (from the LEADERS Trial).
Journal: The American journal of cardiology 20100215
Title: Mammalian target of rapamycin signaling and autophagy: roles in lymphangioleiomyomatosis therapy.
Journal: Proceedings of the American Thoracic Society 20100215
Title: Systemic rapamycin to prevent restenosis: a glimpse to the past?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100215
Title: Is diabetes a leveler of efficacy of DES types?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100215
Title: Sirolimus and temsirolimus for epithelioid angiomyolipoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100210
Title: Clinical activity of mTOR inhibition with sirolimus in malignant perivascular epithelioid cell tumors: targeting the pathogenic activation of mTORC1 in tumors.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100210
Title: A randomized comparison of the Endeavor zotarolimus-eluting stent versus the TAXUS paclitaxel-eluting stent in de novo native coronary lesions 12-month outcomes from the ENDEAVOR IV trial.
Journal: Journal of the American College of Cardiology 20100209
Title: Autophagy impairment inhibits differentiation of glioma stem/progenitor cells.
Journal: Brain research 20100208
Title: The rapamycin-derivative RAD001 (everolimus) inhibits cell viability and interacts with the Akt-mTOR-p70S6K pathway in human medullary thyroid carcinoma cells.
Journal: Molecular and cellular endocrinology 20100205
Title: p70 S6 kinase limits tumor necrosis factor-alpha-induced interleukin-6 synthesis in osteoblast-like cells.
Journal: Molecular and cellular endocrinology 20100205
Title: Insulin-stimulated interaction with 14-3-3 promotes cytoplasmic localization of lipin-1 in adipocytes.
Journal: The Journal of biological chemistry 20100205
Title: Rapamycin enhances the susceptibility of both androgen-dependent and -independent prostate carcinoma cells to docetaxel.
Journal: Chinese medical journal 20100205
Title: A phase II pilot study of tacrolimus/sirolimus GVHD prophylaxis for sibling donor hematopoietic stem cell transplantation using 3 conditioning regimens.
Journal: Blood 20100204
Title: Steroid avoidance using sirolimus and cyclosporine in pediatric renal transplantation: one year analysis.
Journal: Pediatric transplantation 20100201
Title: Cost-effectiveness of immunosuppressive regimens in renal transplant recipients in Germany: a model approach.
Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20100201
Title: Rapamycin-insensitive up-regulation of MMP2 and other genes in tuberous sclerosis complex 2-deficient lymphangioleiomyomatosis-like cells.
Journal: American journal of respiratory cell and molecular biology 20100201
Title: Metabolic control of antifungal drug resistance.
Journal: Fungal genetics and biology : FG & B 20100201
Title: Novel mechanism of rapamycin in GVHD: increase in interstitial regulatory T cells.
Journal: Bone marrow transplantation 20100201
Title: Lower incidence of cytomegalovirus infection with everolimus versus mycophenolate mofetil in de novo cardiac transplant recipients: a randomized, multicenter study.
Journal: Transplant infectious disease : an official journal of the Transplantation Society 20100201
Title: Rapamycin or tacrolimus alone fails to resist cardiac allograft accelerated rejection mediated by alloreactive CD4(+) memory T cells in mice.
Journal: Transplant immunology 20100201
Title: Multicentric outcome analysis of sirolimus-based immunosuppression in 252 liver transplant recipients.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100201
Title: Improved outcomes using tacrolimus/sirolimus for graft-versus-host disease prophylaxis with a reduced-intensity conditioning regimen for allogeneic hematopoietic cell transplant as treatment of myelofibrosis.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20100201
Title: Treatment of renal artery in-stent restenosis with sirolimus-eluting stents.
Journal: Vascular medicine (London, England) 20100201
Title: Rapamycin: the cure for all that ails.
Journal: Journal of molecular cell biology 20100201
Title: Clinical and angiographic outcomes with an everolimus-eluting stent in large coronary arteries: the SPIRIT III 4.0 mm registry.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100201
Title: Coronary stenting with the sirolimus-eluting stent in patients with restenosis after intracoronary brachytherapy: results from the prospective multicentre German Cypher Stent Registry.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20100201
Title: Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species.
Journal: Free radical research 20100201
Title: Bim is the key mediator of glucocorticoid-induced apoptosis and of its potentiation by rapamycin in human myeloma cells.
Journal: Biochimica et biophysica acta 20100201
Title: Calcineurin inhibitors affect B cell antibody responses indirectly by interfering with T cell help.
Journal: Clinical and experimental immunology 20100201
Title: Rapamycin inhibits lung metastasis of B16 melanoma cells through down-regulating alphav integrin expression and up-regulating apoptosis signaling.
Journal: Cancer science 20100201
Title: Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle.
Journal: American journal of physiology. Cell physiology 20100201
Title: Tubular toxicity in sirolimus- and cyclosporine-based transplant immunosuppression strategies: an ancillary study from a randomized controlled trial.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20100201
Title: Delayed correlation of mRNA and protein expression in rapamycin-treated cells and a role for Ggc1 in cellular sensitivity to rapamycin.
Journal: Molecular & cellular proteomics : MCP 20100201
Title: Quantitative nuclear proteomics identifies mTOR regulation of DNA damage response.
Journal: Molecular & cellular proteomics : MCP 20100201
Title: Potential role of everolimus in inducing cholestasis.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20100201
Title: Effect of everolimus on cell viability in nonfunctioning pituitary adenomas.
Journal: The Journal of clinical endocrinology and metabolism 20100201
Title: Coronary stenting with the sirolimus-eluting stent in clinical practice: final results from the prospective multicenter German Cypher Stent Registry.
Journal: Journal of interventional cardiology 20100201
Title: Ultra fast liquid chromatography-tandem mass spectrometry routine method for simultaneous determination of cyclosporin A, tacrolimus, sirolimus, and everolimus in whole blood using deuterated internal standards for cyclosporin A and everolimus.
Journal: Therapeutic drug monitoring 20100201
Title: RAD 001 (everolimus) prevents mTOR and Akt late re-activation in response to imatinib in chronic myeloid leukemia.
Journal: Journal of cellular biochemistry 20100201
Title: Tubular epithelial cell and podocyte apoptosis with de novo sirolimus based immunosuppression in renal allograft recipients with DGF.
Journal: Histology and histopathology 20100201
Title: Comparison of neointimal coverage of sirolimus-eluting stents and paclitaxel-eluting stents using optical coherence tomography at 9 months after implantation.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20100201
Title: Drug-eluting stent fracture: incidence, contributing factors, and clinical implications.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100201
Title: MYC activity mitigates response to rapamycin in prostate cancer through 4EBP1-mediated inhibition of autophagy.
Journal: Autophagy 20100201
Title: Experience with everolimus (RAD001), an oral mammalian target of rapamycin inhibitor, in patients with systemic mastocytosis.
Journal: Leukemia & lymphoma 20100201
Title: Pharmacokinetic sub-study in the SPIRIT III Randomized and Controlled Trial of XIENCE V everolimus eluting coronary stent system.
Journal: Journal of interventional cardiology 20100201
Title: Clinical predictors of proteinuria after conversion to sirolimus in kidney transplant recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100201
Title: Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.
Journal: Nature medicine 20100201
Title: A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer.
Journal: Molecular endocrinology (Baltimore, Md.) 20100201
Title: Broadening the therapeutic scope for rapamycin treatment.
Journal: Autophagy 20100201
Title: New Drugs2010, PART 1.
Journal: Nursing 20100201
Title: Resveratrol and rapamycin: are they anti-aging drugs?
Journal: BioEssays : news and reviews in molecular, cellular and developmental biology 20100201
Title: Surgical biology for the clinician: vascular effects of immunosuppression.
Journal: Canadian journal of surgery. Journal canadien de chirurgie 20100201
Title: Major adverse cardiac events in patients with moderate to severe renal insufficiency treated with first-generation drug-eluting stents.
Journal: The American journal of cardiology 20100201
Title: Augmentation of autophagy by mTOR-inhibition in myocardial infarction: When size matters.
Journal: Autophagy 20100201
Title: Rapamycin inhibits cholangiocyte regeneration by blocking interleukin-6-induced activation of signal transducer and activator of transcription 3 after liver transplantation.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20100201
Title: Rapid improvement of nephrogenic systemic fibrosis with rapamycin therapy: possible role of phospho-70-ribosomal-S6 kinase.
Journal: Journal of the American Academy of Dermatology 20100201
Title: Why do patients develop proteinuria with sirolimus? Do we have the answer?
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20100201
Title: Paclitaxel-eluting versus sirolimus-eluting stents in diabetes mellitus: a report from the National Heart, Lung, and Blood Institute Dynamic Registry.
Journal: Circulation. Cardiovascular interventions 20100201
Title: Dependence on phosphoinositide 3-kinase and RAS-RAF pathways drive the activity of RAF265, a novel RAF/VEGFR2 inhibitor, and RAD001 (Everolimus) in combination.
Journal: Molecular cancer therapeutics 20100201
Title: Outcomes of unselected recipients of sirolimus-eluting stents: the Cypher stent U.S. post-marketing surveillance registry.
Journal: The Journal of invasive cardiology 20100201
Title: Outcomes of overlapping bare-metal stents with sirolimus-eluting stents for long lesions in small coronary vessels.
Journal: The Journal of invasive cardiology 20100201
Title: Diffuse alveolar hemorrhage induced by everolimus.
Journal: Chest 20100201
Title: Sotrastaurin and everolimus pharmacokinetics after single-dose coadministration.
Journal: International journal of clinical pharmacology and therapeutics 20100201
Title: A pooled gender based analysis comparing the XIENCE V(R) everolimus-eluting stent and the TAXUS paclitaxel-eluting stent in male and female patients with coronary artery disease, results of the SPIRIT II and SPIRIT III studies: two-year analysis.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100201
Title: Cost-effectiveness of the Endeavor stent in de novo native coronary artery lesions updated with contemporary data.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100201
Title: A comparison of clinical presentations, angiographic patterns and outcomes of in-stent restenosis between bare metal stents and drug eluting stents.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100201
Title: Effect of drug-eluting stents in patients with acute ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention: a meta-analysis of randomised trials and an adjusted indirect comparison.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100201
Title: Comments on the article by Routledge et al 'Three-year clinical outcome of percutaneous treatment of bifurcation lesions in multivessel coronary artery disease with the sirolimus-eluting stent: insights from the Arterial Revascularisation Therapies Study, part II (ARTS II)'.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100201
Title: Rapamycin inhibits VEGF-induced microvascular hyperpermeability in vivo.
Journal: Microcirculation (New York, N.Y. : 1994) 20100201
Title: Long-term blood vessel removal with combined laser and topical rapamycin antiangiogenic therapy: implications for effective port wine stain treatment.
Journal: Lasers in surgery and medicine 20100201
Title: Impact of multiple and long sirolimus-eluting stent implantation on 3-year clinical outcomes in the j-Cypher Registry.
Journal: JACC. Cardiovascular interventions 20100201
Title: Impact of drug-eluting stent length on outcomes less is more...more or less.
Journal: JACC. Cardiovascular interventions 20100201
Title: Difference of neointimal formational pattern and incidence of thrombus formation among 3 kinds of stents: an angioscopic study.
Journal: JACC. Cardiovascular interventions 20100201
Title: [Effects of rapamycin-loaded poly(lactic-co-glycolic) acid nanoparticles on distribution of cell cycle, expression of p27 protein, and proliferation of human umbilical arterial vascular smooth muscle cell in vitro].
Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20100201
Title: Comparison of long-term results of drug-eluting stent and bare metal stent implantation in heart transplant recipients with coronary artery disease.
Journal: Kardiologia polska 20100201
Title: Influence of drug-eluting stent on inflammation during restenosis in a porcine coronary model.
Journal: Acta cardiologica 20100201
Title: The pathophysiology of tuberous sclerosis complex.
Journal: Epilepsia 20100201
Title: [Intravascular ultrasound evaluation on the efficacy of national made Firebird stents comparing with Cypher stents].
Journal: Zhonghua xin xue guan bing za zhi 20100201
Title: [Treatment of locally advanced renal tumors].
Journal: Actas urologicas espanolas 20100201
Title: Sirolimus-eluting stents versus paclitaxel-eluting stents in patients with chronic renal insufficiency.
Journal: Journal of interventional cardiology 20100201
Title: Resolvin E1 receptor activation signals phosphorylation and phagocytosis.
Journal: The Journal of biological chemistry 20100129
Title: Effect of different immunosuppressive schedules on recurrence-free survival after liver transplantation for hepatocellular carcinoma.
Journal: Transplantation 20100127
Title: Cyclosporine lowering with everolimus or mycophenolate to preserve renal function in heart recipients: a randomized study.
Journal: Transplantation 20100127
Title: Sirolimus-eluting stent implantation in small coronary arteries: a three dimensional intravascular ultrasound study from the SIRIUS trial.
Journal: International journal of cardiology 20100121
Title: Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100120
Title: [mTOR and non-small cell lung cancer].
Journal: Zhongguo fei ai za zhi = Chinese journal of lung cancer 20100120
Title: Second-generation everolimus-eluting and paclitaxel-eluting stents in real-life practice (COMPARE): a randomised trial.
Journal: Lancet (London, England) 20100116
Title: Everolimus or paclitaxel stents in real life: go COMPARE.
Journal: Lancet (London, England) 20100116
Title: Preclinical in vivo evaluation of rapamycin in human malignant peripheral nerve sheath explant xenograft.
Journal: International journal of cancer 20100115
Title: Omega-3 polyunsaturated fatty acids affect sirolimus exposure in kidney transplant recipients on calcineurin inhibitor-free regimen.
Journal: Transplantation 20100115
Title: Myxoma virus virotherapy for glioma in immunocompetent animal models: optimizing administration routes and synergy with rapamycin.
Journal: Cancer research 20100115
Title: The somatostatin analogue octreotide confers sensitivity to rapamycin treatment on pituitary tumor cells.
Journal: Cancer research 20100115
Title: Beyond rapalog therapy: preclinical pharmacology and antitumor activity of WYE-125132, an ATP-competitive and specific inhibitor of mTORC1 and mTORC2.
Journal: Cancer research 20100115
Title: Outcome of undersized drug-eluting stents for percutaneous coronary intervention of saphenous vein graft lesions.
Journal: The American journal of cardiology 20100115
Title: Hybrid inhibitors of phosphatidylinositol 3-kinase (PI3K) and the mammalian target of rapamycin (mTOR): design, synthesis, and superior antitumor activity of novel wortmannin-rapamycin conjugates.
Journal: Journal of medicinal chemistry 20100114
Title: Dysregulation of mTOR signaling in fragile X syndrome.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20100113
Title: Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster.
Journal: Cell metabolism 20100106
Title: Depletion of mammalian target of rapamycin (mTOR) via siRNA mediated knockdown leads to stabilization of beta-catenin and elicits distinct features of cardiomyocyte hypertrophy.
Journal: FEBS letters 20100104
Title: Oral ulcers after a transplant.
Journal: The British journal of oral & maxillofacial surgery 20100101
Title: Everolimus-induced pneumonitis: report of the first case in a liver transplant recipient and review of treatment options.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100101
Title: Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma.
Journal: Journal of neuro-oncology 20100101
Title: Rapamycin promotes arterial thrombosis in vivo: implications for everolimus and zotarolimus eluting stents.
Journal: European heart journal 20100101
Title: Celecoxib reduces the effects of acute and chronic UVB exposure in mice treated with therapeutically relevant immunosuppressive drugs.
Journal: International journal of cancer 20100101
Title: Late conversion of tacrolimus to sirolimus in a prednisone-free immunosuppression regimen in renal transplant patients.
Journal: Clinical transplantation 20100101
Title: mTOR inhibitor everolimus ameliorates progressive tubular dysfunction in chronic renal failure rats.
Journal: Biochemical pharmacology 20100101
Title: The PI3K/Akt and mTOR/P70S6K signaling pathways in human uveal melanoma cells: interaction with B-Raf/ERK.
Journal: Investigative ophthalmology & visual science 20100101
Title: Acute rejection after paediatric heart transplantation: far less common and less severe.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100101
Title: Repeat renal allografts treated with sirolimus, cyclosporine, anti-thymocyte globulin induction and continuous steroids achieve similar immunosuppressive efficacy as primary transplants.
Journal: Clinical transplantation 20100101
Title: Long-term results after conversion from calcineurin inhibitors to sirolimus in renal transplant patients.
Journal: Clinical transplantation 20100101
Title: Acute rejection in low-toxicity regimens: clinical impact and risk factors in the Symphony study.
Journal: Clinical transplantation 20100101
Title: Phase I clinical and pharmacokinetic study of RAD001 (everolimus) administered daily to Japanese patients with advanced solid tumors.
Journal: Japanese journal of clinical oncology 20100101
Title: The sensing of essential amino acid deficiency in the anterior piriform cortex, that requires the uncharged tRNA/GCN2 pathway, is sensitive to wortmannin but not rapamycin.
Journal: Pharmacology, biochemistry, and behavior 20100101
Title: Cost-effectiveness of temsirolimus for first line treatment of advanced renal cell carcinoma.
Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20100101
Title: Rapamycin inhibits yeast nucleotide excision repair independently of tor kinases.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20100101
Title: Rapamycin impairs metabolism-secretion coupling in rat pancreatic islets by suppressing carbohydrate metabolism.
Journal: The Journal of endocrinology 20100101
Title: Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: From tuberous sclerosis to common acquired epilepsies.
Journal: Epilepsia 20100101
Title: Glucocorticoids increase NPY gene expression in the arcuate nucleus by inhibiting mTOR signaling in rat hypothalamic organotypic cultures.
Journal: Peptides 20100101
Title: Rapamycin and CCI-779 inhibit the mammalian target of rapamycin signalling in hepatocellular carcinoma.
Journal: Liver international : official journal of the International Association for the Study of the Liver 20100101
Title: Noncanonical TGF-beta pathways, mTORC1 and Abl, in renal interstitial fibrogenesis.
Journal: American journal of physiology. Renal physiology 20100101
Title: Preliminary characterization of oral lesions associated with inhibitors of mammalian target of rapamycin in cancer patients.
Journal: Cancer 20100101
Title: Aortic dissection in a patient treated by sunitinib for metastatic renal cell carcinoma.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20100101
Title: A novel mTOR activating protein protects dopamine neurons against oxidative stress by repressing autophagy related cell death.
Journal: Journal of neurochemistry 20100101
Title: Expression of metabolically targeted biomarkers in endometrial carcinoma.
Journal: Gynecologic oncology 20100101
Title: Systemic drugs for restenosis prevention: old idea, new drugs.
Journal: Cardiology 20100101
Title: Preventing restenosis after implantation of bare stents with oral rapamycin: a randomized angiographic and intravascular ultrasound study with a 5-year clinical follow-up.
Journal: Cardiology 20100101
Title: Failed rescue therapy with rapamycin after paraquat intoxication.
Journal: Clinical toxicology (Philadelphia, Pa.) 20100101
Title: An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study.
Journal: European heart journal 20100101
Title: Transcription factor GATA4 inhibits doxorubicin-induced autophagy and cardiomyocyte death.
Journal: The Journal of biological chemistry 20100101
Title: The application of electrostatic dry powder deposition technology to coat drug-eluting stents.
Journal: Pharmaceutical research 20100101
Title: A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1.
Journal: Molecular and cellular biology 20100101
Title: Sirolimus-induced signaling modifications in Kaposi's sarcoma with resolution in a liver transplant recipient.
Journal: Clinical transplantation 20100101
Title: Proteinuria after conversion to sirolimus in kidney transplant recipients: impact of pre-existing proteinuria, graft function, and angiotensin-converting enzyme inhibitors/angiotensin-receptor antagonists.
Journal: Clinical transplantation 20100101
Title: Unravelling the endovascular microenvironment by optical coherence tomography.
Journal: European heart journal 20100101
Title: Daily oral everolimus activity in patients with metastatic pancreatic neuroendocrine tumors after failure of cytotoxic chemotherapy: a phase II trial.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100101
Title: Pharmacological modification of dendritic cells to promote their tolerogenicity in transplantation.
Journal: Methods in molecular biology (Clifton, N.J.) 20100101
Title: Recent progress in percutaneous coronary intervention: evolution of the drug-eluting stents, focus on the XIENCE V drug-eluting stent.
Journal: Coronary artery disease 20100101
Title: Treatment of mild-moderate calcified coronary lesions with sirolimus-eluting stent: real world data from a single center.
Journal: Coronary artery disease 20100101
Title: The impact of sirolimus on hepatocyte proliferation after living donor liver transplantation.
Journal: Clinical transplantation 20100101
Title: Anthropogenic factors and the risk of highly pathogenic avian influenza H5N1: prospects from a spatial-based model.
Journal: Veterinary research 20100101
Title: Influence of selective immunosuppressive drugs on the healing of exposed dogs' dental pulp capped with mineral trioxide aggregate.
Journal: Journal of endodontics 20100101
Title: Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3.
Journal: Brain : a journal of neurology 20100101
Title: Pharmacological inhibition of phosphoinositide 3 and TOR kinases improves survival of Drosophila melanogaster.
Journal: Rejuvenation research 20100101
Title: Mammalian target of rapamycin (mTOR) induces proliferation and de-differentiation responses to three coordinate pathophysiologic stimuli (mechanical strain, hypoxia, and extracellular matrix remodeling) in rat bladder smooth muscle.
Journal: The American journal of pathology 20100101
Title: Drug-eluting stents for the treatment of acute myocardial infarction: the view to the HORIZONS.
Journal: Heart, lung & circulation 20100101
Title: Bevacizumab, sorafenib tosylate, sunitinib and temsirolimus for renal cell carcinoma: a systematic review and economic evaluation.
Journal: Health technology assessment (Winchester, England) 20100101
Title: The role of the Akt/mTOR pathway in tobacco carcinogen-induced lung tumorigenesis.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100101
Title: Vorinostat enhances the activity of temsirolimus in renal cell carcinoma through suppression of survivin levels.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20100101
Title: Small-molecule inhibitors of phosphatidylinositol 3-kinase/Akt signaling inhibit Wnt/beta-catenin pathway cross-talk and suppress medulloblastoma growth.
Journal: Cancer research 20100101
Title: Early (fifth day) vs. late (sixth month) steroid withdrawal in renal transplant recipients treated with Neoral(®) plus Rapamune(®): four-yr results of a randomized monocenter study.
Journal: Clinical transplantation 20100101
Title: Reduction of cyclosporine following the introduction of everolimus in maintenance heart transplant recipients: a pilot study.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20100101
Title: Stage 2 combination testing of rapamycin with cytotoxic agents by the Pediatric Preclinical Testing Program.
Journal: Molecular cancer therapeutics 20100101
Title: The ATM inhibitor KU-55933 suppresses cell proliferation and induces apoptosis by blocking Akt in cancer cells with overactivated Akt.
Journal: Molecular cancer therapeutics 20100101
Title: Management of chronic allograft dysfunction by switch over to rapamycin.
Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20100101
Title: Temsirolimus.
Journal: Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20100101
Title: Quantitation of sirolimus using liquid chromatography-tandem mass spectrometry (LC-MS-MS).
Journal: Methods in molecular biology (Clifton, N.J.) 20100101
Title: Persistent effects of everolimus on strength of experimental wounds in intestine and fascia.
Journal: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20100101
Title: Progress in the management of advanced renal cell carcinoma (RCC).
Journal: Aktuelle Urologie 20100101
Title: Long-term laryngeal allograft survival using low-dose everolimus.
Journal: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20100101
Title: Lingual angioedema associated with everolimus.
Journal: Acta oncologica (Stockholm, Sweden) 20100101
Title: Effect of rapamycin on lifespan in Drosophila.
Journal: Geriatrics & gerontology international 20100101
Title: Meta-analysis of five randomized clinical trials comparing sirolimus- versus paclitaxel-eluting stents in patients with diabetes mellitus.
Journal: The American journal of cardiology 20100101
Title: Sirolimus-eluting stent implantation for ostial stenosis of left main coronary artery after Bentall operation in aortitis syndrome.
Journal: Journal of cardiology 20100101
Title: Incidence and predictors of very late (>or=4 years) major cardiac adverse events in the DESIRE (Drug-Eluting Stents in the Real World)-Late registry.
Journal: JACC. Cardiovascular interventions 20100101
Title: First clinical experience of 'flower petal stenting': a novel technique for the treatment of coronary bifurcation lesions.
Journal: JACC. Cardiovascular interventions 20100101
Title: The artisan approach for stenting bifurcation lesions.
Journal: JACC. Cardiovascular interventions 20100101
Title: Anti-CD34 antibodies immobilized on the surface of sirolimus-eluting stents enhance stent endothelialization.
Journal: JACC. Cardiovascular interventions 20100101
Title: Drug-eluting stent endothelium: presence or dysfunction.
Journal: JACC. Cardiovascular interventions 20100101
Title: Increased restenosis rate after implantation of drug-eluting stents in patients with elevated serum activity of matrix metalloproteinase-2 and -9.
Journal: JACC. Cardiovascular interventions 20100101
Title: Regulation of gene expression in hepatic cells by the mammalian Target of Rapamycin (mTOR).
Journal: PloS one 20100101
Title: Lkb1 inactivation is sufficient to drive endometrial cancers that are aggressive yet highly responsive to mTOR inhibitor monotherapy.
Journal: Disease models & mechanisms 20100101
Title: [Stromal progenitor cells and blood leukocytes after implantation of drug-eluting stents].
Journal: Kardiologiia 20100101
Title: Comparison of three rapamycin dosing schedules in A/J Tsc2+/- mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous sclerosis related tumors.
Journal: Journal of translational medicine 20100101
Title: [First-line therapy of metastatic renal cell carcinoma--update 2009].
Journal: Onkologie 20100101
Title: [Current aspects of second-line and sequence therapy of metastatic renal cell carcinoma].
Journal: Onkologie 20100101
Title: [Outlook: Future therapy of renal cell carcinoma].
Journal: Onkologie 20100101
Title: Thrombotic microangiopathy following intestinal transplantation: a single center experience.
Journal: Transplantation proceedings 20100101
Title: Effects of immunosuppressive drugs on rat renal ischemia reperfusion injury.
Journal: Transplantation proceedings 20100101
Title: Everolimus versus azathioprine in a cyclosporine and ketoconazole-based immunosuppressive therapy in kidney transplant: 3-year follow-up of an open-label, prospective, cohort, comparative clinical trial.
Journal: Transplantation proceedings 20100101
Title: Results of the conversion to everolimus in renal transplant recipients with posttransplantation malignancies.
Journal: Transplantation proceedings 20100101
Title: Effectiveness and cost of replacing a calcineurin inhibitor with sirolimus to slow the course of chronic kidney disease in renal allografts.
Journal: Transplantation proceedings 20100101
Title: Conversion to sirolimus allows preservation of renal function in kidney and kidney-pancreas allograft recipients.
Journal: Transplantation proceedings 20100101
Title: South American Heart Transplantation Registry of patients receiving everolimus in their immunosuppressive regimens.
Journal: Transplantation proceedings 20100101
Title: Everolimus in lung transplantation in Chile.
Journal: Transplantation proceedings 20100101
Title: Sirolimus in kidney transplant donors and clinical and histologic improvement in recipients: rat model.
Journal: Transplantation proceedings 20100101
Title: In vitro and in vivo characterization of novel biodegradable polymers for application as drug-eluting stent coatings.
Journal: Journal of biomaterials science. Polymer edition 20100101
Title: mTOR inhibitor-associated dermatologic and mucosal problems.
Journal: Clinical transplantation 20100101
Title: Toxic tacrolimus blood levels with rifampin administration in a renal transplant recipient.
Journal: Annals of transplantation 20100101
Title: Sirolimus-eluting stent fractures leading to restenosis in cardiac allograft vasculopathy.
Journal: Cardiovascular revascularization medicine : including molecular interventions 20100101
Title: Rapamycin induces autophagy and exacerbates metabolism associated complications in a mouse model of type 1 diabetes.
Journal: Indian journal of experimental biology 20100101
Title: New therapeutic strategies for renal cell carcinoma.
Journal: Urologic nursing 20100101
Title: Evaluation of the firebird sirololimus eluting stent in all comers with coronary artery stenosis.
Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20100101
Title: [Toxic effect of immunosuppression agent Everolimus on insuloma cells and pancreatic islets of SD rat].
Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100101
Title: Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease.
Journal: PloS one 20100101
Title: A therapeutic exploratory study to determine the efficacy and safety of calcineurin-inhibitor-free de-novo immunosuppression after liver transplantation: CILT.
Journal: BMC surgery 20100101
Title: VEGF secretion by neuroendocrine tumor cells is inhibited by octreotide and by inhibitors of the PI3K/AKT/mTOR pathway.
Journal: Neuroendocrinology 20100101
Title: Sirolimus-based immunosuppression in kidney transplantation for type 2 diabetic nephropathy.
Journal: Urologia internationalis 20100101
Title: Pulmonary toxicity associated with sirolimus following kidney transplantation: computed tomography findings.
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20100101
Title: Rapamycin inhibits re-endothelialization after percutaneous coronary intervention by impeding the proliferation and migration of endothelial cells and inducing apoptosis of endothelial progenitor cells.
Journal: Texas Heart Institute journal 20100101
Title: [Renal cell carcinoma management and therapies in 2010].
Journal: Bulletin du cancer 20100101
Title: [mTOR inhibitors: temsirolimus and everolimus in the treatment of renal cell carcinoma].
Journal: Bulletin du cancer 20100101
Title: [Targeted therapies: sequential and combined treatments].
Journal: Bulletin du cancer 20100101
Title: [Management of side effects associated with antiangiogenic treatment in renal cell carcinoma].
Journal: Bulletin du cancer 20100101
Title: [Advanced renal carcinomas with special situations. How to treat them?].
Journal: Bulletin du cancer 20100101
Title: [Signalling pathways in renal-cell carcinoma: from the molecular biology to the future therapy].
Journal: Bulletin du cancer 20100101
Title: Epidermal growth factor induces HCCR expression via PI3K/Akt/mTOR signaling in PANC-1 pancreatic cancer cells.
Journal: BMC cancer 20100101
Title: Anti-CD154 mAb and rapamycin induce T regulatory cell mediated tolerance in rat-to-mouse islet transplantation.
Journal: PloS one 20100101
Title: A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma.
Journal: BMC cancer 20100101
Title: Severe aphthous stomatitis associated with oral calcineurin and mTOR inhibitors.
Journal: International journal of dermatology 20100101
Title: Significant sirolimus and dronedarone interaction in a kidney transplant recipient.
Journal: The Annals of pharmacotherapy 20100101
Title: Different immunosuppressive combinations on T-cell regulation in renal transplant recipients.
Journal: American journal of nephrology 20100101
Title: Rapamycin inhibits IGF-1 stimulated cell motility through PP2A pathway.
Journal: PloS one 20100101
Title: Accelerated wound healing by mTOR activation in genetically defined mouse models.
Journal: PloS one 20100101
Title: [Change in regulations for dispensing immunosuppressants to patients who have undergone a kidney transplant].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20100101
Title: Xenotransplantation of hepatocytes in rats with acute liver failure using sirolimus for immunosuppression.
Journal: The Journal of international medical research 20100101
Title: mTOR regulates the invasive properties of synovial fibroblasts in rheumatoid arthritis.
Journal: Molecular medicine (Cambridge, Mass.) 20100101
Title: Rationale and design of a randomized clinical comparison of everolimus-eluting (Xience v/Promus) and sirolimus-eluting (cypher select+) coronary stents in unselected patients with coronary heart disease.
Journal: Cardiology 20100101
Title: mTOR signaling in cancer cell motility and tumor metastasis.
Journal: Critical reviews in eukaryotic gene expression 20100101
Title: Rapamycin pharmacokinetic and pharmacodynamic relationships in osteosarcoma: a comparative oncology study in dogs.
Journal: PloS one 20100101
Title: Drug-eluting stent thrombosis 1,659 days after stent deployment: case report and literature review.
Journal: Texas Heart Institute journal 20100101
Title: New inhibitors of the PI3K-Akt-mTOR pathway: insights into mTOR signaling from a new generation of Tor Kinase Domain Inhibitors (TORKinibs).
Journal: Current topics in microbiology and immunology 20100101
Title: Q-TWiST analysis of patients receiving temsirolimus or interferon alpha for treatment of advanced renal cell carcinoma.
Journal: PharmacoEconomics 20100101
Title: Rapamycin in combination with donor-specific CD4+CD25+Treg cells amplified in vitro might be realize the immune tolerance in clinical organ transplantation.
Journal: Cellular immunology 20100101
Title: Choice of immunosuppression influences cytomegalovirus DNAemia in cynomolgus monkey (Macaca fascicularis) islet allograft recipients.
Journal: Cell transplantation 20100101
Title: Comparison of the effect of preinterventional arterial remodeling on intimal hyperplasia after implantation of a sirolimus- or paclitaxel-eluting stent.
Journal: Cardiology 20100101
Title: Efficacy of sirolimus-eluting stents compared with paclitaxel-eluting stents in an unselected population with coronary artery disease: 24-month outcomes of patients in a prospective non-randomized registry in Southern Turkey.
Journal: International journal of medical sciences 20100101
Title: [Percutaneous copronary intervention using sirolimus-eluting stents may improve long-term prognosis of elderly women].
Journal: Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20100101
Title: Development of encapsulating peritoneal sclerosis in a renal transplant recipient on sirolimus immunotherapy.
Journal: Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20100101
Title: Inhibition of the mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: results of two phase II studies.
Journal: BMC cancer 20100101
Title: Peripheral blood T regulatory cell counts may not predict transplant rejection.
Journal: BMC immunology 20100101
Title: Combination of rapamycin and IL-2 do not affect antigen presentation ability of rat B cell and could promote Tregs proliferation and inhibitory activity.
Journal: Cellular immunology 20100101
Title: [Interstitial pneumonitis from everolimus].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20100101
Title: HIV-1 inhibits autophagy in bystander macrophage/monocytic cells through Src-Akt and STAT3.
Journal: PloS one 20100101
Title: Severe stomatitis complicating immune-suppressive switch after cardiac transplantation.
Journal: Acta chirurgica Belgica 20100101
Title: Similar early complication rate in simultaneous pancreas and kidney recipients on tacrolimus/mycophenolate mofetil versus tacrolimus/sirolimus immunosuppressive regimens.
Journal: Transplantation proceedings 20100101
Title: Calcineurin inhibitors in renal transplantation still needed but in reduced doses: a review.
Journal: Transplantation proceedings 20100101
Title: Antivascular endothelial growth factor in diabetic retinopathy.
Journal: Developments in ophthalmology 20100101
Title: Mammalian target of rapamycin (mTOR) regulates TLR3 induced cytokines in human oral keratinocytes.
Journal: Molecular immunology 20100101
Title: The effects of rapamycin on lens epithelial cell proliferation, migration, and matrix formation: an in vitro study.
Journal: Molecular vision 20100101
Title: Cytostatic and anti-angiogenic effects of temsirolimus in refractory mantle cell lymphoma.
Journal: Journal of hematology & oncology 20100101
Title: Study protocol: a pilot study to determine the safety and efficacy of induction-therapy, de novo MPA and delayed mTOR-inhibition in liver transplant recipients with impaired renal function. PATRON-study.
Journal: BMC nephrology 20100101
Title: Asymptomatic migration of a sirolimus-eluting stent into the aorta.
Journal: Internal medicine (Tokyo, Japan) 20100101
Title: A randomized pilot study of systemic immunosuppression in the treatment of age-related macular degeneration with choroidal neovascularization.
Journal: Retina (Philadelphia, Pa.) 20100101
Title: Metabolic engineering of resveratrol and other longevity boosting compounds.
Journal: BioFactors (Oxford, England) 20100101
Title: Life span extension by resveratrol, rapamycin, and metformin: The promise of dietary restriction mimetics for an healthy aging.
Journal: BioFactors (Oxford, England) 20100101
Title: The DTH effector response and IL-2 are unaffected by cyclosporine A in autoimmune B6D2F1 mice.
Journal: Cellular immunology 20100101
Title: Rationale and design of EXPLORE: a randomized, prospective, multicenter trial investigating the impact of recanalization of a chronic total occlusion on left ventricular function in patients after primary percutaneous coronary intervention for acute ST-elevation myocardial infarction.
Journal: Trials 20100101
Title: Antitumour activity of a potent MEK inhibitor RDEA119/BAY 869766 combined with rapamycin in human orthotopic primary pancreatic cancer xenografts.
Journal: BMC cancer 20100101
Title: Activated mammalian target of rapamycin is a potential therapeutic target in gastric cancer.
Journal: BMC cancer 20100101
Title: Thrombogenicity of sirolimus-eluting stents and bare metal stents: evaluation in the early phase after stent implantation.
Journal: In vivo (Athens, Greece) 20100101
Title: Rapamycin therapy for renal, brain, and skin lesions in a tuberous sclerosis patient.
Journal: Renal failure 20100101
Title: Pretreatment with intraluminal rapamycin nanoparticle perfusion inhibits neointimal hyperplasia in a rabbit vein graft model.
Journal: International journal of nanomedicine 20100101
Title: Small coronary vessel angioplasty: outcomes and technical considerations.
Journal: Vascular health and risk management 20100101
Title: Rapamycin sensitizes T-ALL cells to dexamethasone-induced apoptosis.
Journal: Journal of experimental & clinical cancer research : CR 20100101
Title: Improved outcome after 'bottom-up' immunosuppression in liver transplant recipients with preoperative renal impairment.
Journal: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20100101
Title: Targeted therapy in lymphoma.
Journal: Journal of hematology & oncology 20100101
Title: Rrd1 isomerizes RNA polymerase II in response to rapamycin.
Journal: BMC molecular biology 20100101
Title: Teaching an old drug new tricks: metformin as a targeted therapy for lung cancer.
Journal: Seminars in thoracic and cardiovascular surgery 20100101
Title: A comprehensive map of the mTOR signaling network.
Journal: Molecular systems biology 20100101
Title: Primary PCI for acute anterior wall MI with pulmonary edema and left anterior descending artery ostial stenosis.
Journal: Indian heart journal 20100101
Title: Preclinical evaluation of KIT/PDGFRA and mTOR inhibitors in gastrointestinal stromal tumors using small animal FDG PET.
Journal: Journal of experimental & clinical cancer research : CR 20100101
Title: Niclosamide prevents the formation of large ubiquitin-containing aggregates caused by proteasome inhibition.
Journal: PloS one 20100101
Title: Clinical studies with sirolimus, zotarolimus, everolimus, and biolimus A9 drug-eluting stent systems.
Journal: Current pharmaceutical design 20100101
Title: Sirolimus and its analogs and its effects on vascular diseases.
Journal: Current pharmaceutical design 20100101
Title: The Drosophila FoxA ortholog Fork head regulates growth and gene expression downstream of Target of rapamycin.
Journal: PloS one 20100101
Title: Is it possible to optimize the use of targeted therapies in the treatment of renal cell carcinoma?
Journal: Tumori 20100101
Title: Perspectives in the development of novel treatment approaches.
Journal: Tumori 20100101
Title: Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy.
Journal: Cell death & disease 20100101
Title: [Financial justification of investments into special diet for patients with phenylketonuria].
Journal: Medicinski pregled 20100101
Title: [Long-term follow-up use of 'cypher' sirolimus-eluting stents in patients with coronary heart disease after coronary artery bypass grafting with occlusive lesions of the coronary artery].
Journal: Vestnik rentgenologii i radiologii 20100101
Title: Rapamycin increases the p53/MDM2 protein ratio and p53-dependent apoptosis by translational inhibition of mdm2 in cancer cells.
Journal: Cancer letters 20091228
Title: Impact of reduced nephron mass on cyclosporine- and/or sirolimus-induced nephrotoxicity.
Journal: Transplantation 20091227
Title: Bortezomib can suppress activation of rapamycin-resistant memory T cells without affecting regulatory T-cell viability in non-human primates.
Journal: Transplantation 20091227
Title: A chemical genetic screen for mTOR pathway inhibitors based on 4E-BP-dependent nuclear accumulation of eIF4E.
Journal: Chemistry & biology 20091224
Title: Coronary aneurysm and very late stent thrombosis formation associated with sirolimus-eluting stent implantation.
Journal: Chinese medical journal 20091220
Title: Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction.
Journal: The Journal of biological chemistry 20091218
Title: Breakthrough of the year. The runners-up.
Journal: Science (New York, N.Y.) 20091218
Title: [Autosomal dominant polycystic kidney disease (ADPKD): rapamycin as a new treatment option].
Journal: Praxis 20091216
Title: Pharmacologic induction of CD8+ T cell memory: better living through chemistry.
Journal: Science translational medicine 20091216
Title: Three-dimensional time-of-flight secondary ion mass spectrometry imaging of a pharmaceutical in a coronary stent coating as a function of elution time.
Journal: Analytical chemistry 20091215
Title: TOR-driven aging: speeding car without brakes.
Journal: Cell cycle (Georgetown, Tex.) 20091215
Title: Pseudo-DNA damage response in senescent cells.
Journal: Cell cycle (Georgetown, Tex.) 20091215
Title: Histopathology of clinical coronary restenosis in drug-eluting versus bare metal stents.
Journal: The American journal of cardiology 20091215
Title: Prolonged survival of composite facial allografts in non-human primates associated with posttransplant lymphoproliferative disorder.
Journal: Transplantation 20091215
Title: EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy.
Journal: Science signaling 20091215
Title: Beneficial effects of Mammalian target of rapamycin inhibition on left ventricular remodeling after myocardial infarction.
Journal: Journal of the American College of Cardiology 20091215
Title: Assimilating the current clinical data of fully bioabsorbable stents.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215
Title: Novel fully bioabsorbable salicylate-based sirolimus-eluting stent.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215
Title: OrbusNeich fully absorbable coronary stent platform incorporating dual partitioned coatings.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215
Title: NEVO™: a new generation of sirolimus-eluting coronary stent.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215
Title: Everolimus-eluting bioabsorbable stent--Abbot Vascular programme.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215
Title: Allogeneic hematopoietic stem-cell transplantation for sickle cell disease.
Journal: The New England journal of medicine 20091210
Title: Hematopoietic stem-cell transplantation for adults with sickle cell disease.
Journal: The New England journal of medicine 20091210
Title: Structural identification and characterization of potential degradants of zotarolimus on zotarolimus-coated drug-eluting stents.
Journal: Journal of pharmaceutical and biomedical analysis 20091205
Title: Blockade of Hsp20 phosphorylation exacerbates cardiac ischemia/reperfusion injury by suppressed autophagy and increased cell death.
Journal: Circulation research 20091204
Title: Limited sampling strategies for sirolimus after pediatric renal transplantation.
Journal: Pediatric transplantation 20091201
Title: Optical coherence tomography evaluation of zotarolimus-eluting stents at 9-month follow-up: comparison with sirolimus-eluting stents.
Journal: Heart (British Cardiac Society) 20091201
Title: Phosphorylation of translation factors in response to anoxia in turtles, Trachemys scripta elegans: role of the AMP-activated protein kinase and target of rapamycin signalling pathways.
Journal: Molecular and cellular biochemistry 20091201
Title: Rapid regression of lymphadenopathy upon rapamycin treatment in a child with autoimmune lymphoproliferative syndrome.
Journal: Pediatric blood & cancer 20091201
Title: Treatment with sirolimus ameliorates tacrolimus-induced autoimmune cytopenias after solid organ transplant.
Journal: Pediatric blood & cancer 20091201
Title: Quantitative coronary angiography in the current era: principles and applications.
Journal: Journal of interventional cardiology 20091201
Title: Rapamycin impairs trabecular bone acquisition from high-dose but not low-dose intermittent parathyroid hormone treatment.
Journal: Journal of cellular physiology 20091201
Title: Rapamycin induces the TGFbeta1/Smad signaling cascade in renal mesangial cells upstream of mTOR.
Journal: Cellular signalling 20091201
Title: Transfer from ciclosporin to mycophenolate-sirolimus immunosuppression for chronic renal disease after heart transplantation: safety and efficacy of two regimens.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091201
Title: Rapamycin has dual opposing effects on proteinuric experimental nephropathies: is it a matter of podocyte damage?
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091201
Title: Rapamycin protects against rotenone-induced apoptosis through autophagy induction.
Journal: Neuroscience 20091201
Title: Quality of life in patients with metastatic renal cell carcinoma: the importance of patient-reported outcomes.
Journal: Cancer treatment reviews 20091201
Title: The carina angle-new geometrical parameter associated with periprocedural side branch compromise and the long-term results in coronary bifurcation lesions with main vessel stenting only.
Journal: Journal of interventional cardiology 20091201
Title: Emerging drugs for coronary restenosis: the role of systemic oral agents the in stent era.
Journal: Expert opinion on emerging drugs 20091201
Title: A phase I/II study of the safety and efficacy of the addition of sirolimus to tacrolimus/methotrexate graft versus host disease prophylaxis after allogeneic haematopoietic cell transplantation in paediatric acute lymphoblastic leukaemia (ALL).
Journal: British journal of haematology 20091201
Title: CDKs as therapeutic targets for the human genetic disease tuberous sclerosis?
Journal: European journal of clinical investigation 20091201
Title: Five-year clinical outcomes after coronary stenting of chronic total occlusion using sirolimus-eluting stents: insights from the rapamycin-eluting stent evaluated at Rotterdam Cardiology Hospital-(Research) Registry.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091201
Title: Exploring mammalian target of rapamycin (mTOR) inhibition for treatment of mantle cell lymphoma and other hematologic malignancies.
Journal: Leukemia & lymphoma 20091201
Title: Rapamycin enhances lifespan: at last, an advantage for transplant recipients?
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091201
Title: Pulse mTOR inhibitor treatment effectively controls cyst growth but leads to severe parenchymal and glomerular hypertrophy in rat polycystic kidney disease.
Journal: American journal of physiology. Renal physiology 20091201
Title: The multifunctional role of mTOR in innate immunity: implications for transplant immunity.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20091201
Title: Long-term follow-up of neointimal coverage of sirolimus-eluting stents--evaluation with optical coherence tomography.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20091201
Title: Lack of clinical benefit of improved angiographic results with sirolimus-eluting stents compared with paclitaxel and zotarolimus-eluting stents in patients with acute myocardial infarction undergoing percutaneous coronary intervention.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20091201
Title: Effect of itraconazole on the pharmacokinetics of everolimus administered by different routes in rats.
Journal: Biopharmaceutics & drug disposition 20091201
Title: mTOR regulates skeletal muscle regeneration in vivo through kinase-dependent and kinase-independent mechanisms.
Journal: American journal of physiology. Cell physiology 20091201
Title: Effects of chronic overload on muscle hypertrophy and mTOR signaling in young adult and aged rats.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20091201
Title: Significance and management of proteinuria in kidney transplant recipients.
Journal: Journal of the American Society of Nephrology : JASN 20091201
Title: Five-year clinical follow-up after implantation of the Endeavor zotarolimus-eluting stent: ENDEAVOR I, first-in-human study.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091201
Title: TOR complex 2: a signaling pathway of its own.
Journal: Trends in biochemical sciences 20091201
Title: Characterization of p70 S6 kinase 1 in early development of mouse embryos.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20091201
Title: Mammalian target of rapamycin is a critical regulator of cardiac hypertrophy in spontaneously hypertensive rats.
Journal: Hypertension (Dallas, Tex. : 1979) 20091201
Title: The rationale for mTOR inhibition in epithelial ovarian cancer.
Journal: Expert opinion on investigational drugs 20091201
Title: Low toxicity regimens in renal transplantation: a country subset analysis of the Symphony study.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20091201
Title: Evaluation of in vivo antineoplastic effects of rapamycin in patients with chemotherapy-refractory AML.
Journal: European journal of internal medicine 20091201
Title: Pharmacological retention of oral mucosa progenitor/stem cells.
Journal: Journal of dental research 20091201
Title: Oral rapamycin attenuates atherosclerosis without affecting the arterial responsiveness of resistance vessels in apolipoprotein E-deficient mice.
Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20091201
Title: Targeting mTOR globally in cancer: thinking beyond rapamycin.
Journal: Cell cycle (Georgetown, Tex.) 20091201
Title: Emerging treatment combinations: integrating therapy into clinical practice.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20091201
Title: Targeting translation in acute myeloid leukemia: a new paradigm for therapy?
Journal: Cell cycle (Georgetown, Tex.) 20091201
Title: Impact of sirolimus on the recurrence of hepatocellular carcinoma after liver transplantation.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091201
Title: Improvement of renal function after the switch from a calcineurin inhibitor to everolimus in liver transplant recipients with chronic renal dysfunction.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091201
Title: Delayed neointimalization on drug-eluting stents--speculation from optical coherence tomography.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20091201
Title: Metastatic renal cell carcinoma: current standards of care.
Journal: Clinical journal of oncology nursing 20091201
Title: Management of mTOR inhibitor side effects.
Journal: Clinical journal of oncology nursing 20091201
Title: The role of mTOR in bladder cancer.
Journal: Cancer biology & therapy 20091201
Title: Comparison of sirolimus and paclitaxel-eluting stents for complex coronary lesions: an intravascular ultrasound study.
Journal: The Korean journal of internal medicine 20091201
Title: Rapamycin versus methotrexate in early diffuse systemic sclerosis: results from a randomized, single-blind pilot study.
Journal: Arthritis and rheumatism 20091201
Title: Intravesical delivery of rapamycin suppresses tumorigenesis in a mouse model of progressive bladder cancer.
Journal: Cancer prevention research (Philadelphia, Pa.) 20091201
Title: The molecular, the bad, and the ugly: preventing bladder cancer via mTOR inhibition.
Journal: Cancer prevention research (Philadelphia, Pa.) 20091201
Title: Are we totally clear?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091201
Title: The long-term results of the 'Endeavor' stent.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091201
Title: Rationale and design of the Patient Related OuTcomes with Endeavor versus Cypher stenting Trial (PROTECT): randomized controlled trial comparing the incidence of stent thrombosis and clinical events after sirolimus or zotarolimus drug-eluting stent implantation.
Journal: American heart journal 20091201
Title: Clinical and angiographic comparison of everolimus-eluting and paclitaxel-eluting stents in small coronary arteries: a post hoc analysis of the SPIRIT III randomized trial.
Journal: American heart journal 20091201
Title: Clinical development of temsirolimus, a novel mTOR inhibitor, for treatment of advanced malignancies.
Journal: Seminars in oncology 20091201
Title: Intravenous temsirolimus in cancer patients: clinical pharmacology and dosing considerations.
Journal: Seminars in oncology 20091201
Title: Clinical trial experience with temsirolimus in patients with advanced renal cell carcinoma.
Journal: Seminars in oncology 20091201
Title: Mammalian target of rapamycin: discovery of rapamycin reveals a signaling pathway important for normal and cancer cell growth.
Journal: Seminars in oncology 20091201
Title: Temsirolimus in mantle cell lymphoma and other non-Hodgkin lymphoma subtypes.
Journal: Seminars in oncology 20091201
Title: Evaluating temsirolimus activity in multiple tumors: a review of clinical trials.
Journal: Seminars in oncology 20091201
Title: Preprocedural inflammation does not affect neointimal hyperplasia following everolimus-eluting stent implantation.
Journal: The Journal of invasive cardiology 20091201
Title: Late-acquired stent malapposition after sirolimus-eluting stent implantation following acute coronary syndrome: angiographic, IVUS, OCT and coronary angioscopic observation.
Journal: The Journal of invasive cardiology 20091201
Title: Chinese 'Firebird' brand sirolimus-eluting stent fracture.
Journal: The Journal of invasive cardiology 20091201
Title: Very late subacute thrombosis of a sirolimus-eluting stent after 57 months.
Journal: The Journal of invasive cardiology 20091201
Title: Translational modulation of proteins expressed from bicistronic vectors.
Journal: Molecular imaging 20091201
Title: Effects of delayed rapamycin treatment on renal fibrosis and inflammation in experimental ischemia reperfusion injury.
Journal: Transplantation proceedings 20091201
Title: Potential differences in kidney allograft outcomes between ethnicities when converting to sirolimus base immunosuppression.
Journal: Transplantation proceedings 20091201
Title: Renal function outcomes in kidney transplant recipients after conversion to everolimus-based immunosuppression regimen with CNI reduction or elimination.
Journal: Transplantation proceedings 20091201
Title: Improved 24-hour blood pressure control with sirolimus versus calcineurin inhibitor based immunosuppression in renal transplant recipients.
Journal: Transplantation proceedings 20091201
Title: Immunosuppression using the mammalian target of rapamycin (mTOR) inhibitor everolimus: pilot study shows significant cognitive and affective improvement.
Journal: Transplantation proceedings 20091201
Title: Three year follow-up of the sirolimus-eluting stent and the paclitaxel-eluting stent in daily practice.
Journal: Clinical cardiology 20091201
Title: Prognostic values of C-reactive protein levels on clinical outcome after implantation of sirolimus-eluting stents in patients on hemodialysis.
Journal: Circulation. Cardiovascular interventions 20091201
Title: In-hospital and mid-term clinical outcomes after percutaneous coronary intervention with the use of sirolimus- or paclitaxel-eluting stents.
Journal: Kardiologia polska 20091201
Title: Inhibition of mammalian target of rapamycin as a therapeutic strategy in the management of bladder cancer.
Journal: Cancer biology & therapy 20091201
Title: [Benefits of proliferation signal inhibitors beyond immunosuppression. Vascular protection and experience in heart transplantation].
Journal: Nephrologie & therapeutique 20091201
Title: [Proliferation signal inhibitors: what therapeutic protocols are followed in 2009?].
Journal: Nephrologie & therapeutique 20091201
Title: [Replacing calcineurin inhibitors with proliferation signal inhibitors after kidney transplantation: indications, results, and disadvantages].
Journal: Nephrologie & therapeutique 20091201
Title: The first-generation drug-eluting stents and coronary endothelial dysfunction.
Journal: JACC. Cardiovascular interventions 20091201
Title: 3-year clinical follow-up of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with de novo coronary artery lesions: the SPIRIT II trial (Clinical Evaluation of the Xience V Everolimus Eluting Coronary Stent System in the Treatment of Patients with de novo Native Coronary Artery Lesions).
Journal: JACC. Cardiovascular interventions 20091201
Title: Long-term clinical and economic analysis of the Endeavor zotarolimus-eluting stent versus the cypher sirolimus-eluting stent: 3-year results from the ENDEAVOR III trial (Randomized Controlled Trial of the Medtronic Endeavor Drug [ABT-578] Eluting Coronary Stent System Versus the Cypher Sirolimus-Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions).
Journal: JACC. Cardiovascular interventions 20091201
Title: Late safety, efficacy, and cost-effectiveness of a zotarolimus-eluting stent compared with a paclitaxel-eluting stent in patients with de novo coronary lesions: 2-year follow-up from the ENDEAVOR IV trial (Randomized, Controlled Trial of the Medtronic Endeavor Drug [ABT-578] Eluting Coronary Stent System Versus the Taxus Paclitaxel-Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions).
Journal: JACC. Cardiovascular interventions 20091201
Title: Clinical outcomes after unrestricted implantation of everolimus-eluting stents.
Journal: JACC. Cardiovascular interventions 20091201
Title: Safety and effectiveness of the Endeavor zotarolimus-eluting stent in real-world clinical practice: 12-month data from the E-Five registry.
Journal: JACC. Cardiovascular interventions 20091201
Title: Evaluation in 3 months duration of neointimal coverage after zotarolimus-eluting stent implantation by optical coherence tomography: the ENDEAVOR OCT trial.
Journal: JACC. Cardiovascular interventions 20091201
Title: Progression of late stent malapposition beyond 2 years after sirolimus-eluting stent implantation.
Journal: JACC. Cardiovascular interventions 20091201
Title: Quantifying pharmacologic suppression of cellular senescence: prevention of cellular hypertrophy versus preservation of proliferative potential.
Journal: Aging 20091201
Title: [Are stents eluting sirolimus and paclitaxel equally efficacious?].
Journal: Kardiologia polska 20091201
Title: Rationale and design for the PAINT randomized trial.
Journal: Arquivos brasileiros de cardiologia 20091201
Title: Temsirolimus for the treatment of mantle cell lymphoma.
Journal: Expert review of hematology 20091201
Title: Drug repositioning using in silico compound profiling.
Journal: Future medicinal chemistry 20091201
Title: Cyclin D1 induction by benzo[a]pyrene-7,8-diol-9,10-epoxide via the phosphatidylinositol 3-kinase/Akt/MAPK- and p70s6k-dependent pathway promotes cell transformation and tumorigenesis.
Journal: The Journal of biological chemistry 20091127
Title: Fibrogenesis in kidney transplantation: potential targets for prevention and therapy.
Journal: Transplantation 20091127
Title: Everolimus with very low-exposure cyclosporine a in de novo kidney transplantation: a multicenter, randomized, controlled trial.
Journal: Transplantation 20091127
Title: Discovery of potent and selective inhibitors of the mammalian target of rapamycin (mTOR) kinase.
Journal: Journal of medicinal chemistry 20091126
Title: A rapamycin-sensitive signaling pathway is essential for the full expression of persistent pain states.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20091125
Title: Regulation of SREBP1c expression by mTOR signaling in hepatocytes.
Journal: The Kobe journal of medical sciences 20091124
Title: If mammalian target of metformin indirectly is mammalian target of rapamycin, then the insulin-like growth factor-1 receptor axis will audit the efficacy of metformin in cancer clinical trials.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091120
Title: The role of mTORC1 pathway in intestinal tumorigenesis.
Journal: Cell cycle (Georgetown, Tex.) 20091115
Title: Clinical outcomes after sirolimus-eluting, paclitaxel-eluting, and bare metal stents (from the first phase of the prospective multicenter German DES.DE Registry).
Journal: The American journal of cardiology 20091115
Title: Comparison of the efficacy and safety of zotarolimus-, sirolimus-, and paclitaxel-eluting stents in patients with ST-elevation myocardial infarction.
Journal: The American journal of cardiology 20091115
Title: Rapamycin for refractory acute graft-versus-host disease.
Journal: Transplantation 20091115
Title: [The effect of the different immunosuppression therapy on CD4(+)Foxp3(+) Treg cells in kidney recipients].
Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20091115
Title: Three-year outcomes after sirolimus-eluting stent implantation for unprotected left main coronary artery disease: insights from the j-Cypher registry.
Journal: Circulation 20091110
Title: The 5-year clinical outcomes after a randomized comparison of sirolimus-eluting versus bare-metal stent implantation in patients with ST-segment elevation myocardial infarction.
Journal: Journal of the American College of Cardiology 20091110
Title: Differential healing after sirolimus, paclitaxel, and bare metal stent placement in combination with peroxisome proliferator-activator receptor gamma agonists: requirement for mTOR/Akt2 in PPARgamma activation.
Journal: Circulation research 20091106
Title: Conversion to sirolimus of patients with chronic allograft nephropathy--a retrospective analysis of outcome and influencing factors.
Journal: Langenbeck's archives of surgery 20091101
Title: Therapeutic drug monitoring of everolimus using the dried blood spot method in combination with liquid chromatography-mass spectrometry.
Journal: Journal of pharmaceutical and biomedical analysis 20091101
Title: Variations in the effects on synthesis of amyloid beta protein in modulated autophagic conditions.
Journal: Neurological research 20091101
Title: Rapamycin prevents transforming growth factor-alpha-induced pulmonary fibrosis.
Journal: American journal of respiratory cell and molecular biology 20091101
Title: Phase II trial of temsirolimus in patients with relapsed or refractory multiple myeloma.
Journal: Leukemia research 20091101
Title: Safety and tolerability of sirolimus treatment in patients with autosomal dominant polycystic kidney disease.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091101
Title: Gender-based evaluation of the XIENCE V everolimus-eluting coronary stent system: clinical and angiographic results from the SPIRIT III randomized trial.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091101
Title: Response to imatinib plus sirolimus in advanced chordoma.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20091101
Title: Involvement of mTOR kinase in cytokine-dependent microglial activation and cell proliferation.
Journal: Biochemical pharmacology 20091101
Title: Tumour flare during interruption of temsirolimus treatment for metastatic renal cell cancer.
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20091101
Title: Randomized evaluation of two drug-eluting stents with identical metallic platform and biodegradable polymer but different agents (paclitaxel or sirolimus) compared against bare stents: 1-year results of the PAINT trial.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091101
Title: Critical roles for the TSC-mTOR pathway in β-cell function.
Journal: American journal of physiology. Endocrinology and metabolism 20091101
Title: Rapamycin selectively inhibits expression of an inducible keratin (K6a) in human keratinocytes and improves symptoms in pachyonychia congenita patients.
Journal: Journal of dermatological science 20091101
Title: Predictors and prognosis of stent fracture after sirolimus-eluting stent implantation.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20091101
Title: Cryptosporidiosis in paediatric renal transplantation.
Journal: Pediatric nephrology (Berlin, Germany) 20091101
Title: Spreading of mesothelioma cells is rapamycin-sensitive and requires continuing translation.
Journal: Journal of cellular biochemistry 20091101
Title: Insulin resistance without elevated mammalian target of rapamycin complex 1 activity in muscles of mice fed a high-fat diet.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20091101
Title: Characterization of pneumonitis in patients with advanced non-small cell lung cancer treated with everolimus (RAD001).
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20091101
Title: Distinct subsets of Sit4 holophosphatases are required for inhibition of Saccharomyces cerevisiae growth by rapamycin and zymocin.
Journal: Eukaryotic cell 20091101
Title: Clinical outcomes of sirolimus-eluting stenting after rotational atherectomy.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20091101
Title: Development and validation of a semi-automated assay for the highly sensitive quantification of Biolimus A9 in human whole blood using high-performance liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091101
Title: Morbus Crohn--a disease of failing macroautophagy in the immune system?
Journal: International immunology 20091101
Title: Everolimus but not mycophenolate mofetil therapy is associated with soluble HLA-G expression in heart transplant patients.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20091101
Title: Sirolimus-eluting stent placement for refractory renal artery in-stent restenosis: sustained patency and clinical benefit at 24 months.
Journal: Vascular medicine (London, England) 20091101
Title: The stent-eluting drugs sirolimus and paclitaxel suppress healing of the endothelium by induction of autophagy.
Journal: The American journal of pathology 20091101
Title: Balancing needs and means: the dilemma of the beta-cell in the modern world.
Journal: Diabetes, obesity & metabolism 20091101
Title: Downregulation of 18F-FDG uptake in PET as an early pharmacodynamic effect in treatment of non-small cell lung cancer with the mTOR inhibitor everolimus.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20091101
Title: Interstitial fibrosis quantification in renal transplant recipients randomized to continue cyclosporine or convert to sirolimus.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20091101
Title: A phase I study of the mammalian target of rapamycin inhibitor sirolimus and MEC chemotherapy in relapsed and refractory acute myelogenous leukemia.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20091101
Title: Transplantation: time to rethink immunosuppression by mTOR inhibitors?
Journal: Nature reviews. Nephrology 20091101
Title: HOTLINE II, ISAR-TEST-4 trial, biodegradable stent coatings show promise.
Journal: European heart journal 20091101
Title: Covered stent for the treatment of coronary aneurysm after sirolimus-eluting stent implantation in a patient with Takayasu's arteritis.
Journal: The Journal of invasive cardiology 20091101
Title: Sirolimus therapy for patients with adult polycystic kidney disease: a pilot study.
Journal: Transplantation proceedings 20091101
Title: Rapamycin as a therapy of choice after renal transplantation in a patient with tuberous sclerosis complex.
Journal: Transplantation proceedings 20091101
Title: Usefulness of sirolimus as rescue therapy in heart transplant recipients with renal failure: analysis of the Spanish Multicenter Observational Study (RAPACOR).
Journal: Transplantation proceedings 20091101
Title: [Conversion to rapamycin in liver transpant recipients with renal insufficiency].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20091101
Title: Sirolimus: a novel immunosuppressive drug in heart transplantation.
Journal: Recent patents on cardiovascular drug discovery 20091101
Title: Long-term risk of adverse outcomes and new malignancies in patients treated with oral sirolimus for prevention of restenosis.
Journal: JACC. Cardiovascular interventions 20091101
Title: No association of chromosome 9p21.3 variation with clinical and angiographic outcomes after placement of drug-eluting stents.
Journal: JACC. Cardiovascular interventions 20091101
Title: Comparison of long-term outcomes following sirolimus-eluting stent vs paclitaxel-eluting stent implantation in patients with long calcified coronary lesions.
Journal: Clinical cardiology 20091101
Title: Cost analysis of sirolimus-eluting stents in the Japanese health insurance system.
Journal: International heart journal 20091101
Title: Long-term effects of novel biodegradable, polymer-coated, sirolimus-eluting stents on neointimal formation in a porcine coronary model.
Journal: International heart journal 20091101
Title: [Indications of mTOR inhibitors in liver transplantation].
Journal: Gastroenterologie clinique et biologique 20091101
Title: Everolimus de novo in liver transplantation.
Journal: Gastroenterologie clinique et biologique 20091101
Title: [Minimize kidney failure in transplantation patients with proliferation signal inhibitors].
Journal: Gastroenterologie clinique et biologique 20091101
Title: [Liver transplantation for hepatocellular carcinoma and potential application of PSI].
Journal: Gastroenterologie clinique et biologique 20091101
Title: [Antitumoral effect of proliferation signal inhibitors].
Journal: Gastroenterologie clinique et biologique 20091101
Title: [Side effects of proliferation signal inhibitors and their management].
Journal: Gastroenterologie clinique et biologique 20091101
Title: Impact of sirolimus-eluting stent implantation compared to bare-metal stent implantation for acute myocardial infarction on coronary plaque composition at nine months follow-up: a Virtual Histology intravascular ultrasound analysis. Results from the Leiden MISSION! intervention study.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091101
Title: How should I treat a complex Post-CABG patient?
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091101
Title: Prospective observational study of sirolimus as primary immunosuppression after renal transplantation.
Journal: Transplantation 20091027
Title: Everolimus: in advanced renal cell carcinoma.
Journal: Drugs 20091022
Title: Synergistic anti-cancer effects of immunotoxin and cyclosporin in vitro and in vivo.
Journal: British journal of cancer 20091020
Title: Preparation and in vitro release profiles of drug-eluting controlled biodegradable polymer coating stents.
Journal: Colloids and surfaces. B, Biointerfaces 20091015
Title: A novel PTEN-dependent link to ubiquitination controls FLIPS stability and TRAIL sensitivity in glioblastoma multiforme.
Journal: Cancer research 20091015
Title: Gastric cancer: trastuzumab trial results spur search for other targets.
Journal: Journal of the National Cancer Institute 20091007
Title: mTOR signaling in epileptogenesis: too much of a good thing?
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20091007
Title: Recurrent acute myocardial infarction after 32 months: very late stent thrombosis after sirolimus-eluting stent implantation.
Journal: Chinese medical journal 20091005
Title: Specification of neuronal polarity regulated by local translation of CRMP2 and Tau via the mTOR-p70S6K pathway.
Journal: The Journal of biological chemistry 20091002
Title: Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability.
Journal: The Journal of biological chemistry 20091002
Title: Cell signaling. Aging is RSKy business.
Journal: Science (New York, N.Y.) 20091002
Title: Antitumoral activity of rapamycin mediated through inhibition of HIF-1alpha and VEGF in hepatocellular carcinoma.
Journal: Digestive diseases and sciences 20091001
Title: Pathological finding of sirolimus-eluting stent (SES) restenosis lesion with black hole appearance on intravascular ultrasound.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20091001
Title: Activation of the mammalian target of rapamycin signalling pathway in prostate cancer and its association with patient clinicopathological characteristics.
Journal: BJU international 20091001
Title: Inhibition of mammalian target of rapamycin (mTOR) signalling in C2C12 myoblasts prevents myogenic differentiation without affecting the hyperphosphorylation of 4E-BP1.
Journal: Cellular signalling 20091001
Title: Distribution of angiographic measures of restenosis after drug-eluting stent implantation.
Journal: Heart (British Cardiac Society) 20091001
Title: Growth failure associated with sirolimus: case report.
Journal: Pediatric nephrology (Berlin, Germany) 20091001
Title: Rapamycin-treated mature dendritic cells have a unique cytokine secretion profile and impaired allostimulatory capacity.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20091001
Title: Inhibition of mammalian target of rapamycin signaling potentiates the effects of all-trans retinoic acid to induce growth arrest and differentiation of human acute myelogenous leukemia cells.
Journal: International journal of cancer 20091001
Title: Role of the novel mTOR inhibitor RAD001 (everolimus) in anaplastic thyroid cancer.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20091001
Title: Efficacy of everolimus (RAD001) in patients with advanced NSCLC previously treated with chemotherapy alone or with chemotherapy and EGFR inhibitors.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20091001
Title: Targeting the mammalian target of Rapamycin to inhibit VEGF and cytokines for the treatment of primary effusion lymphoma.
Journal: Leukemia 20091001
Title: Multi-site analytical evaluation of a chemiluminescent magnetic microparticle immunoassay (CMIA) for sirolimus on the Abbott ARCHITECT analyzer.
Journal: Clinical biochemistry 20091001
Title: Effective treatment of advanced colorectal cancer by rapamycin and 5-FU/oxaliplatin monitored by TIMP-1.
Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20091001
Title: Mammalian target of rapamycin is activated in association with myometrial proliferation during pregnancy.
Journal: Endocrinology 20091001
Title: Mechanical properties, drug eluting characteristics and in vivo performance of a genipin-crosslinked chitosan polymeric stent.
Journal: Biomaterials 20091001
Title: Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis.
Journal: Molecular pharmacology 20091001
Title: Increased mycophenolic acid exposure in stable kidney transplant recipients on tacrolimus as compared with those on sirolimus: implications for pharmacokinetics.
Journal: Clinical pharmacology and therapeutics 20091001
Title: Effects of prostaglandin D2 on Na-dependent phosphate transport activity and its intracellular signaling mechanism in osteoblast-like cells.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20091001
Title: Lipopolysaccharide directly alters renal tubule transport through distinct TLR4-dependent pathways in basolateral and apical membranes.
Journal: American journal of physiology. Renal physiology 20091001
Title: The short-term effect on restenosis and thrombosis of a cobalt-chromium stent eluting two drugs in a porcine coronary artery model.
Journal: Journal of interventional cardiology 20091001
Title: Targeted epidermal growth factor receptor nanoparticle bioconjugates for breast cancer therapy.
Journal: Biomaterials 20091001
Title: Inhibition of mTOR attenuates store-operated Ca2+ entry in cells from endarterectomized tissues of patients with chronic thromboembolic pulmonary hypertension.
Journal: American journal of physiology. Lung cellular and molecular physiology 20091001
Title: AMP-activated protein kinase enhances the expression of muscle-specific ubiquitin ligases despite its activation of IGF-1/Akt signaling in C2C12 myotubes.
Journal: Journal of cellular biochemistry 20091001
Title: Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2.
Journal: Blood 20091001
Title: Identification of novel autophagy regulators by a luciferase-based assay for the kinetics of autophagic flux.
Journal: Autophagy 20091001
Title: Cyclosporine and sirolimus pharmacokinetics and drug-to-drug interactions in kidney transplant recipients.
Journal: Fundamental & clinical pharmacology 20091001
Title: Rosiglitazone prevents sirolimus-induced hypomagnesemia, hypokalemia, and downregulation of NKCC2 protein expression.
Journal: American journal of physiology. Renal physiology 20091001
Title: Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo.
Journal: Journal of hepatology 20091001
Title: Immunosuppressive drugs and Tregs: a critical evaluation!
Journal: Clinical journal of the American Society of Nephrology : CJASN 20091001
Title: Expression and mechanism of mammalian target of rapamycin in age-related renal cell senescence and organ aging.
Journal: Mechanisms of ageing and development 20091001
Title: Long-term clinical outcomes and stent thrombosis of sirolimus-eluting versus bare metal stents in patients with end-stage renal disease: results of Korean multicenter angioplasty team (KOMATE) Registry.
Journal: Journal of interventional cardiology 20091001
Title: Significant association of coronary artery calcification in stent delivery route with restenosis after sirolimus-eluting stent implantation.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20091001
Title: Percutaneous treatment with drug-eluting stent vs bypass surgery in patients suffering from chronic stable angina with multivessel disease involving significant proximal stenosis in left anterior descending artery.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20091001
Title: Randomized, non-inferiority trial of three limus agent-eluting stents with different polymer coatings: the Intracoronary Stenting and Angiographic Results: Test Efficacy of 3 Limus-Eluting Stents (ISAR-TEST-4) Trial.
Journal: European heart journal 20091001
Title: Sirolimus-containing graft-versus-host disease prophylaxis in patients with lymphoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091001
Title: Dual inhibition of mitogen-activated protein kinase kinase and mammalian target of rapamycin in differentiated and anaplastic thyroid cancer.
Journal: The Journal of clinical endocrinology and metabolism 20091001
Title: Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility.
Journal: International journal of oncology 20091001
Title: Red blood cells carry out T cell growth and survival bioactivities that are sensitive to cyclosporine A.
Journal: Cellular and molecular life sciences : CMLS 20091001
Title: Focal brain malformations: seizures, signaling, sequencing.
Journal: Epilepsia 20091001
Title: Animal models of focal cortical dysplasia and tuberous sclerosis complex: recent progress toward clinical applications.
Journal: Epilepsia 20091001
Title: Combined Bcl-2/mammalian target of rapamycin inhibition leads to enhanced radiosensitization via induction of apoptosis and autophagy in non-small cell lung tumor xenograft model.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20091001
Title: MYC activity mitigates response to rapamycin in prostate cancer through eukaryotic initiation factor 4E-binding protein 1-mediated inhibition of autophagy.
Journal: Cancer research 20091001
Title: Benefits of drug-eluting stents as compared to bare metal stent in ST-segment elevation myocardial infarction: four year results of the PaclitAxel or Sirolimus-Eluting stent vs bare metal stent in primary angiOplasty (PASEO) randomized trial.
Journal: American heart journal 20091001
Title: SPIRIT IV trial design: a large-scale randomized comparison of everolimus-eluting stents and paclitaxel-eluting stents in patients with coronary artery disease.
Journal: American heart journal 20091001
Title: Significantly lower incidence of early definite stent thrombosis of drug-eluting stents after unrestricted use in Japan using ticlopidine compared to western countries using clopidogrel: a retrospective comparison with western mega-studies.
Journal: Journal of cardiology 20091001
Title: A combined, rational approach towards inhibition of the MEK-ERK and mTOR pathways in pancreatic ductal adenocarcinoma: promise or deja vu?
Journal: Cancer biology & therapy 20091001
Title: Regulation by FK506 and rapamycin of Ca2+ release from the sarcoplasmic reticulum in vascular smooth muscle: the role of FK506 binding proteins and mTOR.
Journal: British journal of pharmacology 20091001
Title: The insulin-like growth factor-1 receptor-targeting antibody, CP-751,871, suppresses tumor-derived VEGF and synergizes with rapamycin in models of childhood sarcoma.
Journal: Cancer research 20091001
Title: Conversion from a calcineurin inhibitor to everolimus therapy in maintenance liver transplant recipients: a prospective, randomized, multicenter trial.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091001
Title: Rapamycin inhibits hepatic fibrosis in rats by attenuating multiple profibrogenic pathways.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091001
Title: Long-term safety and efficacy of sirolimus-eluting stents in Japanese patients: a single-center cohort study.
Journal: The Journal of invasive cardiology 20091001
Title: Rotational atherectomy is useful to treat restenosis lesions due to crushing of a sirolimus-eluting stent implanted in severely calcified lesions: experimental study and initial clinical experience.
Journal: The Journal of invasive cardiology 20091001
Title: Pentagalloylglucose induces autophagy and caspase-independent programmed deaths in human PC-3 and mouse TRAMP-C2 prostate cancer cells.
Journal: Molecular cancer therapeutics 20091001
Title: Relationship between expression of mutant type glutathione S-transferase theta-1 gene and reactivity of rapamycin in myelodysplastic syndrome.
Journal: Hematology (Amsterdam, Netherlands) 20091001
Title: Clinical and angiographic outcomes in diabetics from the ENDEAVOR IV trial: randomized comparison of zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease.
Journal: JACC. Cardiovascular interventions 20091001
Title: Clinical and angiographic results with the next-generation resolute stent system: a prospective, multicenter, first-in-human trial.
Journal: JACC. Cardiovascular interventions 20091001
Title: A generation 2.5 drug-eluting stent?
Journal: JACC. Cardiovascular interventions 20091001
Title: Optimal stent-sizing with intravascular ultrasound contributes to complete neointimal coverage after sirolimus-eluting stent implantation assessed by angioscopy.
Journal: JACC. Cardiovascular interventions 20091001
Title: Optimal stent expansion and complete neointimal coverage: does this association make sense?
Journal: JACC. Cardiovascular interventions 20091001
Title: Current approaches to the use of sirolimus in renal transplantation.
Journal: Transplantation proceedings 20091001
Title: Conversion from calcineurin inhibitors to sirolimus in kidney transplant recipients: a retrospective cohort study.
Journal: Transplantation proceedings 20091001
Title: Human mesenchymal stem cells and immunosuppressive drug interactions in allogeneic responses: an in vitro study using human cells.
Journal: Transplantation proceedings 20091001
Title: [Recent progress in the diagnosis and treatment of aplastic anemia in children].
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20091001
Title: [The role of intracellular signal pathway of mTOR/S6 in CD3+ T lymphocytes of refractory/relapsed aplastic anemia patients].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20091001
Title: Effects of combined inhibition of MEK and mTOR on downstream signaling and tumor growth in pancreatic cancer xenograft models.
Journal: Cancer biology & therapy 20091001
Title: Treatment of acute myocardial infarction with sirolimus-eluting stents results in chronic endothelial dysfunction in the infarct-related coronary artery.
Journal: Circulation. Cardiovascular interventions 20091001
Title: Frontline therapy in mantle cell lymphoma: the role of high-dose therapy and integration of new agents.
Journal: Current hematologic malignancy reports 20091001
Title: DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212.
Journal: Neuron 20090924
Title: Pore-filling nanoporous templates from degradable block copolymers for nanoscale drug delivery.
Journal: ACS nano 20090922
Title: Randomized phase II study comparing two schedules of everolimus in patients with recurrent/metastatic breast cancer: NCIC Clinical Trials Group IND.163.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090920
Title: Triple antiplatelet therapy for clopidogrel resistance with stent malapposition: a case report.
Journal: Chinese medical journal 20090920
Title: Genetic alterations in the phosphoinositide 3-kinase/Akt signaling pathway confer sensitivity of thyroid cancer cells to therapeutic targeting of Akt and mammalian target of rapamycin.
Journal: Cancer research 20090915
Title: Long-Term outcome of drug-eluting stents compared with bare metal stents in ST-segment elevation myocardial infarction: results of the paclitaxel- or sirolimus-eluting stent versus bare metal stent in Primary Angioplasty (PASEO) Randomized Trial.
Journal: Circulation 20090915
Title: Renal cell carcinoma with an emphasis on drug therapy of advanced disease, part 2.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090915
Title: mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells.
Journal: Cancer research 20090915
Title: Inhibition of tumor growth progression by antiandrogens and mTOR inhibitor in a Pten-deficient mouse model of prostate cancer.
Journal: Cancer research 20090915
Title: Mammalian target of rapamycin inhibition prevents glomerular hypertrophy in a model of renal mass reduction.
Journal: Transplantation 20090915
Title: Outcomes with conversion from calcineurin inhibitors to sirolimus after renal transplantation in the context of steroid withdrawal or steroid continuation.
Journal: Transplantation 20090915
Title: [Effects of Rapamycin on angiogenesis and tumor progression in human hepatocellular carcinoma implantation mice].
Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20090915
Title: Sirolimus, bevacizumab, 5-Fluorouracil and irinotecan for advanced colorectal cancer: a pilot study.
Journal: World journal of gastroenterology 20090914
Title: Impact of drug-eluting stent selection on long-term clinical outcomes in patients treated for unprotected left main coronary artery disease: the sirolimus vs paclitaxel drug-eluting stent for left main registry (SP-DELFT).
Journal: International journal of cardiology 20090911
Title: The Vam6 GEF controls TORC1 by activating the EGO complex.
Journal: Molecular cell 20090911
Title: Mutation of a phosphorylatable residue in Put3p affects the magnitude of rapamycin-induced PUT1 activation in a Gat1p-dependent manner.
Journal: The Journal of biological chemistry 20090904
Title: mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging.
Journal: Cell stem cell 20090904
Title: Ribavirin enhances interferon signaling via stimulation of mTOR and p53 activities.
Journal: FEBS letters 20090903
Title: Silent very late thrombotic occlusion of sirolimus-eluting stent confirmed by directional coronary atherectomy.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20090901
Title: Effective inhibition of xenografts of hepatocellular carcinoma (HepG2) by rapamycin and bevacizumab in an intrahepatic model.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20090901
Title: The effect of rapamycin on bone growth in rabbits.
Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20090901
Title: Calcineurin inhibitor minimization in pediatric liver allograft recipients.
Journal: Pediatric transplantation 20090901
Title: Novel and evolving therapies in the treatment of malignant phaeochromocytoma: experience with the mTOR inhibitor everolimus (RAD001).
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090901
Title: Everolimus restores gefitinib sensitivity in resistant non-small cell lung cancer cell lines.
Journal: Biochemical pharmacology 20090901
Title: Molecular mechanisms of pancreatic dysfunction induced by protein malnutrition.
Journal: Gastroenterology 20090901
Title: Oral rapamycin reduces tumour burden and vascularization in Lkb1(+/-) mice.
Journal: The Journal of pathology 20090901
Title: Monotherapy rapamycin allows an increase of CD4 CD25 FoxP3 T cells in renal recipients.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20090901
Title: S6 kinase 1 knockout inhibits uninephrectomy- or diabetes-induced renal hypertrophy.
Journal: American journal of physiology. Renal physiology 20090901
Title: Synergistic effect of rapamycin and cisplatin in endometrial cancer cells.
Journal: Cancer 20090901
Title: Sirolimus-related dyspnoea, airway obstruction and pleural effusion after lung transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20090901
Title: Long-term administration of rapamycin reduces adiposity, but impairs glucose tolerance in high-fat diet-fed KK/HlJ mice.
Journal: Basic & clinical pharmacology & toxicology 20090901
Title: Calcineurin-mediated GABA(A) receptor dephosphorylation in rats after kainic acid-induced status epilepticus.
Journal: Seizure 20090901
Title: Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer.
Journal: Gastroenterology 20090901
Title: Twenty-four months clinical outcomes of sirolimus-eluting stents for the treatment of small coronary arteries: the long-term SES-SMART clinical study.
Journal: European heart journal 20090901
Title: Mammalian target of rapamycin inhibitors rapamycin and RAD001 (everolimus) induce anti-proliferative effects in GH-secreting pituitary tumor cells in vitro.
Journal: Endocrine-related cancer 20090901
Title: Inhibition of PKHD1 may cause S-phase entry via mTOR signaling pathway.
Journal: Cell biology international 20090901
Title: Management of sorafenib, sunitinib, and temsirolimus toxicity in metastatic renal cell carcinoma.
Journal: Current opinion in supportive and palliative care 20090901
Title: Rapamycin inhibits hepatectomy-induced stimulation of metastatic tumor growth by reduction of angiogenesis, microvascular blood perfusion, and tumor cell proliferation.
Journal: Annals of surgical oncology 20090901
Title: An imbalance in Akt/mTOR is involved in the apoptotic and acantholytic processes in a mouse model of pemphigus vulgaris.
Journal: Experimental dermatology 20090901
Title: Successful control of intractable hypoglycemia using rapamycin in an 86-year-old man with a pancreatic insulin-secreting islet cell tumor and metastases.
Journal: The Journal of clinical endocrinology and metabolism 20090901
Title: The growing importance of mTORC1-S6K1 signaling in kidney.
Journal: American journal of physiology. Renal physiology 20090901
Title: Rapamycin by itself and additively in combination with carboplatin inhibits the growth of ovarian cancer cells.
Journal: Gynecologic oncology 20090901
Title: Prophylactic immune tolerance induced by changing the ratio of antigen-specific effector to regulatory T cells.
Journal: Journal of thrombosis and haemostasis : JTH 20090901
Title: Rapamycin, the mTOR kinase inhibitor, sensitizes acute myeloid leukemia cells, HL-60 cells, to the cytotoxic effect of arabinozide cytarabine.
Journal: Anti-cancer drugs 20090901
Title: Randomised trial of three rapamycin-eluting stents with different coating strategies for the reduction of coronary restenosis: 2-year follow-up results.
Journal: Heart (British Cardiac Society) 20090901
Title: A small GTPase, human Rab32, is required for the formation of autophagic vacuoles under basal conditions.
Journal: Cellular and molecular life sciences : CMLS 20090901
Title: Quantification of nuclear protein transport using induced heterodimerization.
Journal: Traffic (Copenhagen, Denmark) 20090901
Title: Infrapopliteal application of sirolimus-eluting versus bare metal stents for critical limb ischemia: analysis of long-term angiographic and clinical outcome.
Journal: Journal of vascular and interventional radiology : JVIR 20090901
Title: Three-year prognosis of Japanese patients with ST-elevation myocardial infarction treated with sirolimus-eluting stents.
Journal: Coronary artery disease 20090901
Title: Posttransplantation hypomagnesemia and its relation with immunosuppression as predictors of new-onset diabetes after transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090901
Title: Influence of sirolimus on cyclosporine-induced pancreas islet dysfunction in rats.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090901
Title: Treatment with rapamycin ameliorates clinical and histological signs of protracted relapsing experimental allergic encephalomyelitis in Dark Agouti rats and induces expansion of peripheral CD4+CD25+Foxp3+ regulatory T cells.
Journal: Journal of autoimmunity 20090901
Title: Rapamycin enhances platelet aggregation induced by adenosine diphosphate in vitro.
Journal: Platelets 20090901
Title: Systematic gene expression profile of hypothalamus in calorie-restricted mice implicates the involvement of mTOR signaling in neuroprotective activity.
Journal: Mechanisms of ageing and development 20090901
Title: Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling.
Journal: Nature neuroscience 20090901
Title: CCR5 blockade in combination with rapamycin prolongs cardiac allograft survival in mice.
Journal: Clinical and experimental immunology 20090901
Title: Advanced neointimal growth is not associated with a low risk of in-stent thrombus. Optical coherence tomographic findings after first-generation drug-eluting stent implantation.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20090901
Title: CD137 ligand-mediated reverse signals increase cell viability and cytokine expression in murine myeloid cells: involvement of mTOR/p70S6 kinase and Akt.
Journal: European journal of immunology 20090901
Title: Increasing longevity through caloric restriction or rapamycin feeding in mammals: common mechanisms for common outcomes?
Journal: Aging cell 20090901
Title: Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss.
Journal: Nature neuroscience 20090901
Title: mTOR is a promising therapeutic target both in cisplatin-sensitive and cisplatin-resistant clear cell carcinoma of the ovary.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090901
Title: Insulin-like growth factor-1 receptor inhibition induces a resistance mechanism via the epidermal growth factor receptor/HER3/AKT signaling pathway: rational basis for cotargeting insulin-like growth factor-1 receptor and epidermal growth factor receptor in hepatocellular carcinoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090901
Title: Concurrent and sequential administration of chemotherapy and the Mammalian target of rapamycin inhibitor temsirolimus in human cancer cells and xenografts.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090901
Title: 5-year clinical outcomes after sirolimus-eluting stent implantation insights from a patient-level pooled analysis of 4 randomized trials comparing sirolimus-eluting stents with bare-metal stents.
Journal: Journal of the American College of Cardiology 20090901
Title: Rapamycin--rather than FK506--might promote allograft tolerance induced by CD4+CD25+ regulatory T cells.
Journal: Surgery 20090901
Title: Images in cardiovascular medicine: Late abnormal vessel wall reaction 3 years after sirolimus-eluting stent implantation.
Journal: Circulation 20090901
Title: Very late stent thrombosis of sirolimus-eluting stent combined with late stent malapposition and aneurysm formation.
Journal: The Journal of invasive cardiology 20090901
Title: Long-term follow-up after drug eluting stent implantation in left main trifurcations.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090901
Title: Bifurcation stenting with drug-eluting stents: a systematic review and meta-analysis of randomised trials.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090901
Title: Scanning electron microscopic assessment of the biodegradable coating on expanded biolimus-eluting stents.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090901
Title: Proliferation signal inhibitors for the treatment of refractory autoimmune rheumatic diseases: a new therapeutic option.
Journal: Annals of the New York Academy of Sciences 20090901
Title: Early sirolimus therapy in renal transplant recipients at high risk: is it justified?
Journal: Transplantation proceedings 20090901
Title: Conversion to sirolimus for chronic allograft nephropathy and calcineurin inhibitor toxicity and the adverse effects of sirolimus after conversion.
Journal: Transplantation proceedings 20090901
Title: Impact of vessel size on angiographic and clinical outcomes of revascularization with biolimus-eluting stent with biodegradable polymer and sirolimus-eluting stent with durable polymer the LEADERS trial substudy.
Journal: JACC. Cardiovascular interventions 20090901
Title: Effect of balloon inflation time on expansion of sirolimus-eluting stent.
Journal: Heart and vessels 20090901
Title: Resolution of late sirolimus-eluting stent thrombosis after tirofiban treatment.
Journal: Heart and vessels 20090901
Title: [Bemusement and strategy on the efficacy of clinical application of targeted anticancer drugs].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20090901
Title: [Effect of signal transduction inhibitors on human endometrial carcinoma cells with differential PTEN gene expression].
Journal: Zhonghua fu chan ke za zhi 20090901
Title: [Clinical study of application of sirolimus with dose-reduced or discontinued cyclosporine A for prevention of acute rejection after kidney transplantation].
Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20090901
Title: Cell signaling. Blocking Akt-ivity.
Journal: Science (New York, N.Y.) 20090828
Title: Indirect antitumor effects of mammalian target of rapamycin inhibitors against Kaposi sarcoma in transplant patients.
Journal: Transplantation 20090827
Title: Long-term clinical outcomes of sirolimus- versus paclitaxel-eluting stents for patients with unprotected left main coronary artery disease: analysis of the MAIN-COMPARE (revascularization for unprotected left main coronary artery stenosis: comparison of percutaneous coronary angioplasty versus surgical revascularization) registry.
Journal: Journal of the American College of Cardiology 20090825
Title: Letter by Movahed regarding article, 'Randomized Study of the Crush Technique Versus Provisional Side-Branch Stenting in True Coronary Bifurcations: The CACTUS (Coronary Bifurcations: Application of the Crushing Technique Using Sirolimus-Eluting Stents) Study'.
Journal: Circulation 20090825
Title: Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia.
Journal: Blood 20090820
Title: Sirolimus-eluting stent treatment at high-volume centers confers lower mortality at 6-month follow-up: results from the prospective multicenter German Cypher Registry.
Journal: Circulation 20090818
Title: Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells.
Journal: Autophagy 20090816
Title: Targeted inhibition of mammalian target of rapamycin for the treatment of advanced renal cell carcinoma.
Journal: Cancer 20090815
Title: Analysis of PTEN and HIF-1alpha and correlation with efficacy in patients with advanced renal cell carcinoma treated with temsirolimus versus interferon-alpha.
Journal: Cancer 20090815
Title: Pirfenidone inhibits T-cell activation, proliferation, cytokine and chemokine production, and host alloresponses.
Journal: Transplantation 20090815
Title: Minimization of maintenance immunosuppression early after renal transplantation: an interim analysis.
Journal: Transplantation 20090815
Title: Increased interleukin-10 production without expansion of CD4+CD25+ T-regulatory cells in early stable renal transplant patients on calcineurin inhibitors.
Journal: Transplantation 20090815
Title: Is the intracellular ATP concentration of CD4+ T-Cells a predictive biomarker of immune status in stable transplant recipients?
Journal: Transplantation 20090815
Title: Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.
Journal: Genes & development 20090815
Title: A Rab escort protein integrates the secretion system with TOR signaling and ribosome biogenesis.
Journal: Genes & development 20090815
Title: Opposing role of condensin and radiation-sensitive gene RAD52 in ribosomal DNA stability regulation.
Journal: The Journal of biological chemistry 20090814
Title: Rapamycin inhibits poly(ADP-ribosyl)ation in intact cells.
Journal: Biochemical and biophysical research communications 20090814
Title: Phase III study to evaluate temsirolimus compared with investigator's choice therapy for the treatment of relapsed or refractory mantle cell lymphoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090810
Title: The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20090804
Title: Use of a novel anti-proliferative compound coated on a biopolymer to mitigate platelet-derived growth factor-induced proliferation in human aortic smooth muscle cells: comparison with sirolimus.
Journal: Glycoconjugate journal 20090801
Title: Participation of mammalian target of rapamycin complex 1 in Toll-like receptor 2- and 4-induced neutrophil activation and acute lung injury.
Journal: American journal of respiratory cell and molecular biology 20090801
Title: Short and long-term benefits of sirolimus-eluting stent in ST-segment elevation myocardial infarction: a meta-analysis of randomized trials.
Journal: Journal of thrombosis and thrombolysis 20090801
Title: Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma.
Journal: Journal of cellular and molecular medicine 20090801
Title: Rapamycin for focal segmental glomerulosclerosis: a report of 3 cases.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20090801
Title: Long-term rapamycin therapy in the Han:SPRD rat model of polycystic kidney disease (PKD).
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090801
Title: Clinical impact of sirolimus-eluting stent in ST-segment elevation myocardial infarction: a meta-analysis of randomized clinical trials.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090801
Title: Therapeutic role of sirolimus in non-transplant kidney disease.
Journal: Pharmacology & therapeutics 20090801
Title: Everolimus, a promising medical therapy for coronary heart disease?
Journal: Medical hypotheses 20090801
Title: Clinical and angiographic outcomes following percutaneous coronary intervention with sirolimus-eluting stents versus bare-metal stents in hemodialysis patients.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20090801
Title: Gastric mammalian target of rapamycin signaling regulates ghrelin production and food intake.
Journal: Endocrinology 20090801
Title: The role of MTOR in mouse uterus during embryo implantation.
Journal: Reproduction (Cambridge, England) 20090801
Title: Rapamycin inhibition of the Akt/mTOR pathway blocks select stages of VEGF-A164-driven angiogenesis, in part by blocking S6Kinase.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20090801
Title: In vitro interactions between antifungals and immunosuppressive drugs against zygomycetes.
Journal: Antimicrobial agents and chemotherapy 20090801
Title: Autophagy is required for extension of yeast chronological life span by rapamycin.
Journal: Autophagy 20090801
Title: Effect of rapamycin on cue-induced drug craving in abstinent heroin addicts.
Journal: European journal of pharmacology 20090801
Title: Testosterone induces cardiomyocyte hypertrophy through mammalian target of rapamycin complex 1 pathway.
Journal: The Journal of endocrinology 20090801
Title: Rapamycin prevents concanavalin A-induced liver injury by inhibiting lymphocyte activation.
Journal: Journal of gastroenterology and hepatology 20090801
Title: Clinical grade preparation of human natural regulatory T-cells encoding the thymidine kinase suicide gene as a safety gene: authors' reponse.
Journal: The journal of gene medicine 20090801
Title: Posttransplant anemia: the role of sirolimus.
Journal: Kidney international 20090801
Title: Infusion of mesenchymal stem cells and rapamycin synergize to attenuate alloimmune responses and promote cardiac allograft tolerance.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090801
Title: Performance of the new mycophenolate assay based on IMPDH enzymatic activity for pharmacokinetic investigations and setup of Bayesian estimators in different populations of allograft recipients.
Journal: Therapeutic drug monitoring 20090801
Title: Biochemical, cellular, and in vivo activity of novel ATP-competitive and selective inhibitors of the mammalian target of rapamycin.
Journal: Cancer research 20090801
Title: Enhanced interaction between Hsp90 and raptor regulates mTOR signaling upon T cell activation.
Journal: Molecular immunology 20090801
Title: Quiz page August 2009: Respiratory distress 5 years after kidney transplantation.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20090801
Title: Are drug-eluting stents safe?: Definitely! Or probably... possibly? Or maybe not yet...
Journal: Clinical pharmacology and therapeutics 20090801
Title: A spontaneous acinar cell carcinoma model for monitoring progression of pancreatic lesions and response to treatment through noninvasive bioluminescence imaging.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090801
Title: Comparison of radiosensitizing effects of the mammalian target of rapamycin inhibitor CCI-779 to cisplatin in experimental models of head and neck squamous cell carcinoma.
Journal: Molecular cancer therapeutics 20090801
Title: A fractured sirolimus-eluting stent with a coronary aneurysm.
Journal: The Annals of thoracic surgery 20090801
Title: Mid-term angiographic benefit of sirolimus-eluting stents compared with paclitaxel-eluting stents in patients with acute myocardial infarction.
Journal: Journal of cardiology 20090801
Title: Coronary aneurysm associated with coronary perforation after sirolimus-eluting stents implantation: close follow-up exceeding 2 years by coronary 3-dimensional computed tomography.
Journal: Journal of cardiology 20090801
Title: A case of a newly developed yellow neointima at stent implanted site 1 year after sirolimus-eluting stent placement: angioscopic findings.
Journal: Journal of cardiology 20090801
Title: Rapamycin delays tumor development in murine livers by inhibiting proliferation of hepatocytes with DNA damage.
Journal: Hepatology (Baltimore, Md.) 20090801
Title: SES for AMI: moving in the right direction.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090801
Title: Black hole phenomenon observed on IVUS after late restenosis following sirolimus-eluting stent implantation.
Journal: The Journal of invasive cardiology 20090801
Title: The effects of sirolimus on urothelial lesions chemically induced in ICR mice by BBN.
Journal: Anticancer research 20090801
Title: [Effects of rapamycin on prostate cancer PC-3 cells].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20090801
Title: Incomplete stent apposition after coronary stent implantation: myth or reality?
Journal: Journal of interventional cardiology 20090801
Title: Predictive factors of re-restenosis after repeated sirolimus-eluting stent implantation for SES restenosis and clinical outcomes after percutaneous coronary intervention for SES restenosis.
Journal: Journal of interventional cardiology 20090801
Title: Eosinophilic rash secondary to temsirolimus.
Journal: Clinical genitourinary cancer 20090801
Title: In-hospital and 1-year outcomes among unselected percutaneous coronary intervention patients treated with either sirolimus- or paclitaxel-eluting stents: results from the EVENT (Evaluation of Drug Eluting Stents and Ischemic Events) registry.
Journal: JACC. Cardiovascular interventions 20090801
Title: Angiographic restenosis and clinical recurrence after sirolimus- and paclitaxel-eluting stent implantation.
Journal: JACC. Cardiovascular interventions 20090801
Title: Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease.
Journal: JACC. Cardiovascular interventions 20090801
Title: Stent expansion at the segment with thrombus.
Journal: JACC. Cardiovascular interventions 20090801
Title: [Effect of rapamycin on leukemia cell lines].
Journal: Zhongguo shi yan xue ye xue za zhi 20090801
Title: Effect of coadministered HIV-protease inhibitors on tacrolimus and sirolimus blood concentrations in a kidney transplant recipient.
Journal: Fundamental & clinical pharmacology 20090801
Title: Live fast, die young: new lessons in mammalian longevity.
Journal: Rejuvenation research 20090801
Title: Biolimus-eluting biodegradable polymer versus sirolimus-eluting permanent polymer stent performance in long lesions: results from the LEADERS multicentre trial substudy.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090801
Title: Angiographic and intravascular ultrasound findings following implantation of the Endeavor zotarolimus-eluting stents in patients from the real-world clinical practice.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090801
Title: Immunosuppressants: JC virus encephalopathy. Rare but fatal.
Journal: Prescrire international 20090801
Title: Novel role for the Saccharomyces cerevisiae oligopeptide transporter Opt2 in drug detoxification.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20090801
Title: [Bronchiolitis obliterans with organizing pneumonia associated with sirolimus in a patient after liver transplantation].
Journal: Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20090801
Title: Comparison of temsirolimus pharmacokinetics in patients with renal cell carcinoma not receiving dialysis and those receiving hemodialysis: a case series.
Journal: Clinical therapeutics 20090801
Title: Two-year clinical, angiographic, and intravascular ultrasound follow-up of the XIENCE V everolimus-eluting stent in the treatment of patients with de novo native coronary artery lesions: the SPIRIT II trial.
Journal: Circulation. Cardiovascular interventions 20090801
Title: Contrast enhanced sonography shows superior microvascular renal allograft perfusion in patients switched from cyclosporine A to everolimus.
Journal: Transplantation 20090727
Title: The use of intra-coronary optical coherence tomography for the assessment of sirolimus-eluting stent fracture.
Journal: International journal of cardiology 20090724
Title: Infectious tolerance via the consumption of essential amino acids and mTOR signaling.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20090721
Title: Extracellular matrix binding mixed micelles for drug delivery applications.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20090720
Title: Different edge effects of paclitaxel- and sirolimus-eluting stents on proximal and distal edges in patients with unstable angina: serial intravascular ultrasound analysis.
Journal: Chinese medical journal 20090720
Title: Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
Journal: Nature 20090716
Title: Ageing: A midlife longevity drug?
Journal: Nature 20090716
Title: Comparison of rapamycin- and paclitaxel-eluting stents in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction.
Journal: The American journal of cardiology 20090715
Title: Incidence of delayed graft function and wound healing complications after deceased-donor kidney transplantation is not affected by de novo everolimus.
Journal: Transplantation 20090715
Title: Everolimus with reduced cyclosporine versus MMF with standard cyclosporine in de novo heart transplant recipients.
Journal: Transplantation 20090715
Title: Comparison of inflammatory response after implantation of sirolimus- and paclitaxel-eluting stents in porcine coronary arteries.
Journal: Circulation 20090714
Title: The everolimus-eluting stent in real-world patients: 6-month follow-up of the X-SEARCH (Xience V Stent Evaluated at Rotterdam Cardiac Hospital) registry.
Journal: Journal of the American College of Cardiology 20090714
Title: The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential.
Journal: Biochemical and biophysical research communications 20090710
Title: Sirolimus can reverse resistance to gemcitabine, capecitabine and docetaxel combination therapy in pancreatic cancer.
Journal: JOP : Journal of the pancreas 20090706
Title: mTOR regulates memory CD8 T-cell differentiation.
Journal: Nature 20090702
Title: Immunology: A metabolic switch to memory.
Journal: Nature 20090702
Title: RAD001 (everolimus) inhibits tumour growth in xenograft models of human hepatocellular carcinoma.
Journal: Journal of cellular and molecular medicine 20090701
Title: Disposition of desipramine, a sensitive cytochrome P450 2D6 substrate, when coadministered with intravenous temsirolimus.
Journal: Cancer chemotherapy and pharmacology 20090701
Title: Phospho-mTOR and phospho-4EBP1 in endometrial adenocarcinoma: association with stage and grade in vivo and link with response to rapamycin treatment in vitro.
Journal: Journal of cancer research and clinical oncology 20090701
Title: Rapamycin-induced proteinuria following allogeneic hematopoietic stem cell transplantation.
Journal: Bone marrow transplantation 20090701
Title: Amniotic membrane transplantation induces apoptosis in T lymphocytes in murine corneas with experimental herpetic stromal keratitis.
Journal: Investigative ophthalmology & visual science 20090701
Title: Microarray analyses of the effects of NF-kappaB or PI3K pathway inhibitors on the LPS-induced gene expression profile in RAW264.7 cells: synergistic effects of rapamycin on LPS-induced MMP9-overexpression.
Journal: Cellular signalling 20090701
Title: Performance characteristics of a no-pretreatment, random access sirolimus assay for the Dimension RxL clinical chemistry system.
Journal: Clinical biochemistry 20090701
Title: Sirolimus-eluting stents, bare metal stents or coronary artery bypass grafting for patients with multivessel disease including involvement of the proximal left anterior descending artery: analysis of the Arterial Revascularization Therapies study part 2 (ARTS-II).
Journal: Heart (British Cardiac Society) 20090701
Title: A novel role for the Drosophila epsin (lqf): involvement in autophagy.
Journal: Autophagy 20090701
Title: An insight into the mechanistic role of p53-mediated autophagy induction in response to proteasomal inhibition-induced neurotoxicity.
Journal: Autophagy 20090701
Title: The pharmacokinetics of mycophenolate mofetil in renal transplant recipients receiving standard-dose or low-dose cyclosporine, low-dose tacrolimus or low-dose sirolimus: the Symphony pharmacokinetic substudy.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090701
Title: Long-term clinical and angiographic outcomes after implantation of sirolimus-eluting stents with a 'modified mini-crush' technique in coronary bifurcation lesions.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090701
Title: The incidence and predictors of postprocedural incomplete stent apposition after angiographically successful drug-eluting stent implantation.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090701
Title: RAD001 (Everolimus) induces autophagy in acute lymphoblastic leukemia.
Journal: Autophagy 20090701
Title: Practical recommendations for the early use of m-TOR inhibitors (sirolimus) in renal transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20090701
Title: Optimal management of metastatic renal cell carcinoma: an algorithm for treatment.
Journal: BJU international 20090701
Title: Rapamycin inhibits mTORC1, but not completely.
Journal: Autophagy 20090701
Title: Improved long-term prognosis of elderly women in the era of sirolimus-eluting stents.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20090701
Title: Regulation and function of proline oxidase under nutrient stress.
Journal: Journal of cellular biochemistry 20090701
Title: Late progression of renal pathology and cyst enlargement is reduced by rapamycin in a mouse model of nephronophthisis.
Journal: Kidney international 20090701
Title: Rapamycin enhances LPS induction of tissue factor and tumor necrosis factor-alpha expression in macrophages by reducing IL-10 expression.
Journal: Molecular immunology 20090701
Title: FK506 and rapamycin neuroprotect erection and involve different immunophilins in a rat model of cavernous nerve injury.
Journal: The journal of sexual medicine 20090701
Title: The impact of everolimus versus mycophenolate on blood and lymphocyte cyclosporine exposure in heart-transplant recipients.
Journal: European journal of clinical pharmacology 20090701
Title: Limited sampling strategies for the estimation of sirolimus daily exposure in kidney transplant recipients on a calcineurin inhibitor-free regimen.
Journal: Journal of clinical pharmacology 20090701
Title: Rapamycin enhances aplaviroc anti-HIV activity: implications for the clinical development of novel CCR5 antagonists.
Journal: Antiviral research 20090701
Title: Effect of autophagy on multiple myeloma cell viability.
Journal: Molecular cancer therapeutics 20090701
Title: Considerations in sirolimus use in the early and late post-transplant periods.
Journal: Expert opinion on drug safety 20090701
Title: (18)F-FDG and (18)F-FLT uptake early after cyclophosphamide and mTOR inhibition in an experimental lymphoma model.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090701
Title: The 'mini-crush' technique for managing bifurcation lesions.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090701
Title: Comparison of Tacrolimus and Sirolimus (Tac/Sir) versus Tacrolimus, Sirolimus, and mini-methotrexate (Tac/Sir/MTX) as acute graft-versus-host disease prophylaxis after reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090701
Title: Sirolimus as primary treatment of acute graft-versus-host disease following allogeneic hematopoietic cell transplantation.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090701
Title: Relationship between severity of renal impairment and 2-year outcomes after sirolimus-eluting stent implantation.
Journal: American heart journal 20090701
Title: Relationship between neointimal coverage of sirolimus-eluting stents and lesion characteristics: a study with serial coronary angioscopy.
Journal: American heart journal 20090701
Title: Transplantation: To convert or not to convert: lessons from the CONVERT trial.
Journal: Nature reviews. Nephrology 20090701
Title: 'Rapping' on the door of drug resistance.
Journal: Leukemia & lymphoma 20090701
Title: Targeting mammalian target of rapamycin to both downregulate and disable the P-glycoprotein pump in multidrug-resistant B-cell lymphoma cell lines.
Journal: Leukemia & lymphoma 20090701
Title: [Renal epithelioid angiomyolipoma].
Journal: Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20090701
Title: Everolimus.
Journal: Nature reviews. Drug discovery 20090701
Title: Long-term outcomes comparison of different types of DES in elderly patients from a real-world experience.
Journal: The Journal of invasive cardiology 20090701
Title: Defining the optimal treatment for elderly patients: lessons from real-world data.
Journal: The Journal of invasive cardiology 20090701
Title: Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates.
Journal: Nature medicine 20090701
Title: [Mammalian target of rapamycin, its mode of action and clinical response in metastatic clear cell carcinoma].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20090701
Title: Late stent malapposition with marked positive vascular remodeling observed only at the site of drug-eluting stents after multivessel coronary stenting.
Journal: Heart and vessels 20090701
Title: Different vascular response to concurrent implantation of sirolimus- and zotarolimus-eluting stents in the same vessel.
Journal: Heart and vessels 20090701
Title: Impact of sex on 3-year outcome after percutaneous coronary intervention using bare-metal and drug-eluting stents in previously untreated coronary artery disease: insights from the RESEARCH (Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital) and T-SEARCH (Taxus-Stent Evaluated at Rotterdam Cardiology Hospital) Registries.
Journal: JACC. Cardiovascular interventions 20090701
Title: The efficacy of drug-eluting stents in women: a window of opportunity.
Journal: JACC. Cardiovascular interventions 20090701
Title: Population pharmacokinetics of sirolimus in de novo Chinese adult renal transplant patients.
Journal: British journal of clinical pharmacology 20090701
Title: [The mTOR inhibitor enhances chemosensitivity of androgen-independent prostate cancer cell line].
Journal: Zhonghua nan ke xue = National journal of andrology 20090701
Title: Use of a cocktail regimen consisting of soluble galectin-1, rapamycin and histone deacetylase inhibitor may effectively prevent type 1 diabetes.
Journal: Archives of medical research 20090701
Title: New mTOR inhibitor for renal cell cancer.
Journal: Oncology (Williston Park, N.Y.) 20090701
Title: The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1.
Journal: Aging 20090701
Title: Overproduction of cyclin D1 is dependent on activated mTORC1 signal in nasopharyngeal carcinoma: implication for therapy.
Journal: Cancer letters 20090628
Title: A novel accelerated in vitro release method for biodegradable coating of drug eluting stents: Insight to the drug release mechanisms.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628
Title: Mesenchymal stem cell and immunosuppressive drug interactions.
Journal: Transplantation 20090627
Title: Distribution pattern of neointimal hyperplasia following sirolimus-eluting stent implantation assessed by 3-dimensional intravascular ultrasound.
Journal: International journal of cardiology 20090626
Title: GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer.
Journal: Nature 20090625
Title: Inhibition of the mammalian target of rapamycin signaling pathway suppresses dentate granule cell axon sprouting in a rodent model of temporal lobe epilepsy.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090624
Title: Randomized comparison of minimally invasive direct coronary artery bypass surgery versus sirolimus-eluting stenting in isolated proximal left anterior descending coronary artery stenosis.
Journal: Journal of the American College of Cardiology 20090623
Title: Down-regulation of mTOR leads to up-regulation of osteoprotegerin in bone marrow cells.
Journal: Biochemical and biophysical research communications 20090619
Title: m(en)TOR(ing) differentiating T helper cells.
Journal: Immunity 20090619
Title: Sirolimus and everolimus induce endothelial cellular senescence via sirtuin 1 down-regulation: therapeutic implication of cilostazol after drug-eluting stent implantation.
Journal: Journal of the American College of Cardiology 20090616
Title: Aging-suppressants: cellular senescence (hyperactivation) and its pharmacologic deceleration.
Journal: Cell cycle (Georgetown, Tex.) 20090615
Title: Rapamycin decelerates cellular senescence.
Journal: Cell cycle (Georgetown, Tex.) 20090615
Title: Forever young, slim and fit: rapamycin to the rescue.
Journal: Cell cycle (Georgetown, Tex.) 20090615
Title: Pharmacologic inhibition of MEK and PI-3K converges on the mTOR/S6 pathway to decelerate cellular senescence.
Journal: Cell cycle (Georgetown, Tex.) 20090615
Title: TORC1 controls degradation of the transcription factor Stp1, a key effector of the SPS amino-acid-sensing pathway in Saccharomyces cerevisiae.
Journal: Journal of cell science 20090615
Title: Tacrolimus/sirolimus versus tacrolimus/mycophenolate in kidney transplantation: improved 3-year graft and patient survival in recent era.
Journal: Transplantation 20090615
Title: Fluvastatin accelerates re-endothelialization impaired by local sirolimus treatment.
Journal: European journal of pharmacology 20090610
Title: Biphasic activation of the mTOR pathway in the gustatory cortex is correlated with and necessary for taste learning.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090610
Title: Deregulation of mTOR signaling is involved in thymic lymphoma development in Atm-/- mice.
Journal: Biochemical and biophysical research communications 20090605
Title: FDG uptake is a surrogate marker for defining the optimal biological dose of the mTOR inhibitor everolimus in vivo.
Journal: British journal of cancer 20090602
Title: Comparison of inflammatory markers and angiographic outcomes after implantation of sirolimus and paclitaxel-eluting stents.
Journal: Heart (British Cardiac Society) 20090601
Title: Apoptosis of CD4(+)CD25(high) T cells in response to Sirolimus requires activation of T cell receptor and is modulated by IL-2.
Journal: Cancer immunology, immunotherapy : CII 20090601
Title: Polylactide-glycoli acid and rapamycin coating intraocular lens prevent posterior capsular opacification in rabbit eyes.
Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20090601
Title: Monitoring kidney and renal cyst volumes applying MR approaches on a rapamycin treated mouse model of ADPKD.
Journal: Magma (New York, N.Y.) 20090601
Title: High prevalence of ovarian cysts in premenopausal women receiving sirolimus and tacrolimus after clinical islet transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20090601
Title: Rapamycin, but not cyclosporine A, inhibits vascularization and incorporation of implanted surgical meshes.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20090601
Title: Combined inhibition of Dnmt and mTOR signaling inhibits formation and growth of colorectal cancer.
Journal: International journal of colorectal disease 20090601
Title: Combination of immunosuppressive drugs leaves specific 'fingerprint' on gene expression in vitro.
Journal: Immunopharmacology and immunotoxicology 20090601
Title: Generation of high-yield rapamycin-producing strains through protoplasts-related techniques.
Journal: Applied microbiology and biotechnology 20090601
Title: Lung cavitation due to Mycobacterium xenopi in a renal transplant recipient.
Journal: Transplant infectious disease : an official journal of the Transplantation Society 20090601
Title: Sirolimus-associated lymphoedema: eight new cases and a proposed mechanism.
Journal: The British journal of dermatology 20090601
Title: Intracellular parasitism with Toxoplasma gondii stimulates mammalian-target-of-rapamycin-dependent host cell growth despite impaired signalling to S6K1 and 4E-BP1.
Journal: Cellular microbiology 20090601
Title: A phase 2 study with a daily regimen of the oral mTOR inhibitor RAD001 (everolimus) in patients with metastatic clear cell renal cell cancer.
Journal: Cancer 20090601
Title: Mammalian target of rapamycin inhibitors and their potential role in therapy in leukaemia and other haematological malignancies.
Journal: British journal of haematology 20090601
Title: Rapamycin selectively reduces the association of transcripts containing complex 5' UTRs with ribosomes in C4-2B prostate cancer cells.
Journal: Journal of cellular biochemistry 20090601
Title: Immunosuppressive therapy in lung transplantation: state of the art.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20090601
Title: Severe multivessel coronary spasm after sirolimus-eluting stent implantation.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20090601
Title: Intervention for jailed diagonal branch is not necessary while stenting the left anterior descending artery.
Journal: Journal of interventional cardiology 20090601
Title: Delayed neointimalization on sirolimus-eluting stents: 6-month and 12-month follow up by optical coherence tomography.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20090601
Title: Assessment of sirolimus-eluting coronary stent implantation with aspirin plus low dose ticlopidine administration: one year results from CYPHER Stent Japan Post-Marketing Surveillance Registry (J-PMS).
Journal: Circulation journal : official journal of the Japanese Circulation Society 20090601
Title: Comparison of low vs moderate dose of atorvastatin in clopidogrel resistance after coronary stenting in Korean patients with acute coronary syndrome.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20090601
Title: Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090601
Title: [18F]fluorodeoxyglucose positron emission tomography correlates with Akt pathway activity but is not predictive of clinical outcome during mTOR inhibitor therapy.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090601
Title: Sirolimus as primary immunosuppression is associated with improved coronary vasomotor function compared with calcineurin inhibitors in stable cardiac transplant recipients.
Journal: European heart journal 20090601
Title: Leucine restriction inhibits chondrocyte proliferation and differentiation through mechanisms both dependent and independent of mTOR signaling.
Journal: American journal of physiology. Endocrinology and metabolism 20090601
Title: Antagonism of the mammalian target of rapamycin selectively mediates metabolic effects of epidermal growth factor receptor inhibition and protects human malignant glioma cells from hypoxia-induced cell death.
Journal: Brain : a journal of neurology 20090601
Title: Expression of mTOR pathway proteins in human amniotic fluid stem cells.
Journal: International journal of molecular medicine 20090601
Title: The methylation of the TSC2 promoter underlies the abnormal growth of TSC2 angiomyolipoma-derived smooth muscle cells.
Journal: The American journal of pathology 20090601
Title: Black and white: rapamycin as a regulator of cardiac mTOR signaling.
Journal: Cell cycle (Georgetown, Tex.) 20090601
Title: Let it be, let it be.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090601
Title: Strategies for drug-eluting stent treatment of bifurcation coronary artery disease in the United States: insights from the e-Cypher S.T.L.L.R.trial.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090601
Title: Combined inhibition of MEK and mammalian target of rapamycin abolishes phosphorylation of cyclin-dependent kinase 4 in glioblastoma cell lines and prevents their proliferation.
Journal: Cancer research 20090601
Title: Improved cardiac function after sirolimus-eluting stent placement in diabetic patients by pioglitazone: combination therapy with statin.
Journal: Journal of cardiology 20090601
Title: Absence of proteinuria predicts improvement in renal function after conversion to sirolimus-based immunosuppressive regimens in lung transplant survivors with chronic kidney disease.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20090601
Title: Adverse effects of nicotine and immunosuppression on proximal tubular epithelial cell viability, tissue repair and oxidative stress gene expression.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20090601
Title: Rapamycin down-regulates inducible nitric oxide synthase by inducing proteasomal degradation.
Journal: Biological & pharmaceutical bulletin 20090601
Title: Overexpression of thymosin beta4 increases pseudopodia formation in LNCaP prostate cancer cells.
Journal: Biological & pharmaceutical bulletin 20090601
Title: Long-term clinical follow-up after sirolimus-eluting stent versus bare metal stent implantation in patients with acute coronary syndrome.
Journal: Journal of interventional cardiology 20090601
Title: Everolimus (RAD001): an mTOR inhibitor for the treatment of metastatic renal cell carcinoma.
Journal: Expert review of anticancer therapy 20090601
Title: First-in-man use of polymer-free valsartan-eluting stents in small coronary vessels: a comparison to polymer-free rapamycin (2%)-eluting stents.
Journal: Journal of the renin-angiotensin-aldosterone system : JRAAS 20090601
Title: Validation of the type 1 insulin-like growth factor receptor as a therapeutic target in renal cancer.
Journal: Molecular cancer therapeutics 20090601
Title: Simultaneous blockade of the epidermal growth factor receptor/mammalian target of rapamycin pathway by epidermal growth factor receptor inhibitors and rapamycin results in reduced cell growth and survival in biliary tract cancer cells.
Journal: Molecular cancer therapeutics 20090601
Title: Cyclooxygenase 2 mediates the antiangiogenic effect of rapamycin in Ewing sarcoma.
Journal: Journal of pediatric surgery 20090601
Title: Infarct size is increased in female post-MI rats treated with rapamycin.
Journal: Canadian journal of physiology and pharmacology 20090601
Title: Impact of stent length on restenosis in patients with acute myocardial infarction treated with primary percutaneous coronary intervention: analysis based on data from the Trial to Assess the Use of the Cypher Stent in Acute Myocardial Infarction Treated with Balloon Angioplasty (TYPHOON).
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601
Title: Reproducibility of quantitative optical coherence tomography for stent analysis.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601
Title: Treatment of refractory chronic urticaria with sirolimus.
Journal: Archives of dermatology 20090601
Title: Conversion from calcineurin inhibitors to sirolimus reduces vascularization and thickness of post-transplant cutaneous squamous cell carcinomas.
Journal: Anticancer research 20090601
Title: Inhibition of IGF-I receptor signaling in combination with rapamycin or temsirolimus increases MYC-N phosphorylation.
Journal: Anticancer research 20090601
Title: The role of antiangiogenesis therapy: bevacizumab and beyond.
Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20090601
Title: Efficacy of combined inhibition of mTOR and ERK/MAPK pathways in treating a tuberous sclerosis complex cell model.
Journal: Journal of genetics and genomics = Yi chuan xue bao 20090601
Title: Impact of target lesion and nontarget lesion cardiac events on 5-year clinical outcomes after sirolimus-eluting or bare-metal stenting.
Journal: JACC. Cardiovascular interventions 20090601
Title: The PASEO (PaclitAxel or Sirolimus-Eluting Stent Versus Bare Metal Stent in Primary Angioplasty) Randomized Trial.
Journal: JACC. Cardiovascular interventions 20090601
Title: The risk of stent thrombosis in patients with acute coronary syndromes treated with bare-metal and drug-eluting stents.
Journal: JACC. Cardiovascular interventions 20090601
Title: Clinical impact of polymorphisms of transport proteins and enzymes involved in the metabolism of immunosuppressive drugs.
Journal: Transplantation proceedings 20090601
Title: Long-term follow-up of 100 high-risk renal transplant recipients converted from calcineurin inhibitors to sirolimus: a single center experience.
Journal: Transplantation proceedings 20090601
Title: The effect of Malononitrilamides (FK778) on phenotypic properties of human peripheral dendritic cells.
Journal: Transplantation proceedings 20090601
Title: Effect of cyclosporine and sirolimus on fatty acid desaturase activities in cultured HEPG2 cells.
Journal: Transplantation proceedings 20090601
Title: [Effects of sirolimus on the growth of transplanted hepatocellular carcinoma].
Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090601
Title: Two-year outcomes of the sirolimus-eluting stent according to unprotected left main lesion.
Journal: Clinical cardiology 20090601
Title: [The MULTISTRATEGY study].
Journal: Giornale italiano di cardiologia (2006) 20090601
Title: Decreased acute rejection and improved renal allograft survival using sirolimus and low-dose calcineurin inhibitors without induction therapy.
Journal: The International journal of artificial organs 20090601
Title: [Combined rapamycin eye drop in nanometer vector and poly (lactic acid) wafers of cyclosporine A effectively prevents high-risk corneal allograft rejection in rabbits].
Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20090601
Title: Randomized comparison of the Nobori Biolimus A9-eluting coronary stent with the Taxus Liberté paclitaxel-eluting coronary stent in patients with stenosis in native coronary arteries: the NOBORI 1 trial--Phase 2.
Journal: Circulation. Cardiovascular interventions 20090601
Title: Bioabsorbable coronary stents.
Journal: Circulation. Cardiovascular interventions 20090601
Title: 'Intracoronary whirling current phenomenon' and thrombus formation after sirolimus-eluting stent implantation visualized by optical coherence tomography.
Journal: Circulation. Cardiovascular interventions 20090601
Title: Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy.
Journal: Aging 20090601
Title: Three-year clinical outcome of percutaneous treatment of bifurcation lesions in multivessel coronary artery disease with the sirolimus-eluting stent: insights from the Arterial Revascularisation Therapies Study, part II (ARTS II).
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601
Title: Long-term outcome after the V stenting technique in de novo bifurcation lesions using drug-eluting stents.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601
Title: Percutaneous coronary intervention with oral sirolimus and bare metal stents has comparable safety and efficacy to treatment with drug eluting stents, but with significant cost saving: long-term follow-up results from the randomised, controlled ORAR III (Oral Rapamycin in ARgentina) study.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601
Title: Impact of plasma and whole-blood anticoagulant counter ion choice on drug stability and matrix effects during bioanalysis.
Journal: Bioanalysis 20090601
Title: Impressive sirolimus-eluting stent fracture immediately after stent implantation: a case report.
Journal: International journal of cardiology 20090529
Title: Changes in sodium pump expression dictate the effects of ouabain on cell growth.
Journal: The Journal of biological chemistry 20090529
Title: Mammalian target of rapamycin complex 1 (mTORC1) activity is associated with phosphorylation of raptor by mTOR.
Journal: The Journal of biological chemistry 20090529
Title: Akt signals through the mammalian target of rapamycin pathway to regulate CNS myelination.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090527
Title: The mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsy.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090527
Title: [Monitoring and adjustment of immunosuppression after heart transplantation].
Journal: Revue medicale suisse 20090527
Title: Fluorescent probes to characterise FK506-binding proteins.
Journal: Chembiochem : a European journal of chemical biology 20090525
Title: Multimodal dynamic imaging of therapeutic biomedical coatings in aqueous medium.
Journal: Langmuir : the ACS journal of surfaces and colloids 20090519
Title: Chemopreventive efficacy of rapamycin on Peutz-Jeghers syndrome in a mouse model.
Journal: Cancer letters 20090518
Title: Acute myocardial infarction as a consequence of stent fracture and plaque rupture after sirolimus-eluting stent implantation.
Journal: International journal of cardiology 20090515
Title: Various optical coherence tomographic findings in restenotic lesions after sirolimus-eluting stent implantation.
Journal: International journal of cardiology 20090515
Title: Use of multiple overlapping sirolimus-eluting stents for treatment of long coronary artery lesions: results from a single-center registry in 318 consecutive patients.
Journal: International journal of cardiology 20090515
Title: Targeting mTOR in renal cell carcinoma.
Journal: Cancer 20090515
Title: Acute liver transplant rejection upon immunosuppression withdrawal in a tolerance induction trial: potential role of IFN-gamma-secreting CD8+ T cells.
Journal: Transplantation 20090515
Title: Long-term treatment of sirolimus but not cyclosporine ameliorates diabetic nephropathy in the rat.
Journal: Transplantation 20090515
Title: The challenge of achieving target drug concentrations in clinical trials: experience from the Symphony study.
Journal: Transplantation 20090515
Title: Disposition of everolimus in mdr1a-/1b- mice and after a pre-treatment of lapatinib in Swiss mice.
Journal: Biochemical pharmacology 20090515
Title: Predictors of heightened platelet reactivity despite dual-antiplatelet therapy in patients undergoing percutaneous coronary intervention.
Journal: The American journal of cardiology 20090515
Title: Rapamycin prevents early onset of tumorigenesis in an oral-specific K-ras and p53 two-hit carcinogenesis model.
Journal: Cancer research 20090515
Title: Paclitaxel- versus sirolimus-eluting stents for unprotected left main coronary artery disease.
Journal: Journal of the American College of Cardiology 20090512
Title: Left main coronary artery stenting: crossing the Rubicon.
Journal: Journal of the American College of Cardiology 20090512
Title: Regulation of RNA polymerase III transcription involves SCH9-dependent and SCH9-independent branches of the target of rapamycin (TOR) pathway.
Journal: The Journal of biological chemistry 20090508
Title: XAP2 inhibits glucocorticoid receptor activity in mammalian cells.
Journal: FEBS letters 20090506
Title: A prospective, randomized, 6-month comparison of the coronary vasomotor response associated with a zotarolimus- versus a sirolimus-eluting stent: differential recovery of coronary endothelial dysfunction.
Journal: Journal of the American College of Cardiology 20090505
Title: Differences in restenosis rate with different drug-eluting stents in patients with and without diabetes mellitus: a report from the SCAAR (Swedish Angiography and Angioplasty Registry).
Journal: Journal of the American College of Cardiology 20090505
Title: Successful treatment of a child having generalized Kaposi's sarcoma after living donor liver transplantation with conversion to sirolimus.
Journal: Pediatric transplantation 20090501
Title: Experiences and practical conclusions concerning temsirolimus use and adverse event management in advanced renal cell carcinoma within a compassionate use program in Germany.
Journal: Cancer chemotherapy and pharmacology 20090501
Title: Sirolimus inhibits the growth and metastatic progression of hepatocellular carcinoma.
Journal: Journal of cancer research and clinical oncology 20090501
Title: PTEN deficiency is a common defect in juvenile myelomonocytic leukemia.
Journal: Leukemia research 20090501
Title: Calcineurin inhibitor-free GVHD prophylaxis with sirolimus, mycophenolate mofetil and ATG in Allo-SCT for leukemia patients with high relapse risk: an observational cohort study.
Journal: Bone marrow transplantation 20090501
Title: Decrease in sirolimus-induced proteinuria after switch to everolimus in a liver transplant recipient with diabetic nephropathy.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20090501
Title: Impact of clopidogrel resistance on thrombotic events after percutaneous coronary intervention with drug-eluting stent.
Journal: Thrombosis research 20090501
Title: Induction of iodide uptake in transformed thyrocytes: a compound screening in cell lines.
Journal: European journal of nuclear medicine and molecular imaging 20090501
Title: Suppression of mTOR complex 2-dependent AKT phosphorylation in melanoma cells by combined treatment with rapamycin and LY294002.
Journal: The British journal of dermatology 20090501
Title: Ready for a comeback of natural products in oncology.
Journal: Biochemical pharmacology 20090501
Title: Differential effects of immunosuppressive drugs on COX-2 activity in vitro and in kidney transplant patients in vivo.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090501
Title: Assaying autophagic activity in transgenic GFP-Lc3 and GFP-Gabarap zebrafish embryos.
Journal: Autophagy 20090501
Title: Novel agents for renal cell carcinoma require novel selection paradigms to optimise first-line therapy.
Journal: Cancer treatment reviews 20090501
Title: The eIF4E-binding proteins are modifiers of cytoplasmic eIF4E relocalization during the heat shock response.
Journal: American journal of physiology. Cell physiology 20090501
Title: LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.
Journal: Acta physiologica (Oxford, England) 20090501
Title: Tolerability of first-line therapy for metastatic renal cell carcinoma.
Journal: Cancer treatment reviews 20090501
Title: Recent advances in molecular targeted therapy for metastatic renal cell carcinoma.
Journal: International journal of urology : official journal of the Japanese Urological Association 20090501
Title: [Targeted therapies and their indications in solid neoplasias].
Journal: La Revue de medecine interne 20090501
Title: Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters.
Journal: Autophagy 20090501
Title: Comparative healing response after sirolimus- and paclitaxel-eluting stent implantation in a pig model of restenosis.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090501
Title: Targeting of mTOR is associated with decreased growth and decreased VEGF expression in acute myeloid leukaemia cells.
Journal: European journal of clinical investigation 20090501
Title: Long-term small molecule and protein elution from TiO2 nanotubes.
Journal: Nano letters 20090501
Title: Rapamycin reduces high-amplitude, mechanical stretch-induced apoptosis in pulmonary microvascular endothelial cells.
Journal: Microvascular research 20090501
Title: Targeting the mTOR signaling network for cancer therapy.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090501
Title: Progress in the treatment of neuroendocrine tumors.
Journal: Current oncology reports 20090501
Title: Targeted therapies in metastatic renal cancer in 2009.
Journal: BJU international 20090501
Title: Early and limited use of tacrolimus to avoid rejection in an alemtuzumab and sirolimus regimen for kidney transplantation: clinical results and immune monitoring.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090501
Title: Ultra-performance hydrophilic interaction liquid chromatography/tandem mass spectrometry for the determination of everolimus in mouse plasma.
Journal: Rapid communications in mass spectrometry : RCM 20090501
Title: Re-restenosis and target lesion revascularization after treatment of sirolimus-eluting stent restenosis: retrospective analysis of 4 Japanese hospitals.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20090501
Title: Adenovirus-mediated eukaryotic initiation factor 4E binding protein-1 in combination with rapamycin inhibits tumor growth of pancreatic ductal adenocarcinoma in vivo.
Journal: International journal of oncology 20090501
Title: Atg17 recruits Atg9 to organize the pre-autophagosomal structure.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20090501
Title: Efficacy of Xience/promus versus Cypher in rEducing Late Loss after stENTing (EXCELLENT) trial: study design and rationale of a Korean multicenter prospective randomized trial.
Journal: American heart journal 20090501
Title: Relationship of deregulated signaling converging onto mTOR with prognosis and classification of lung adenocarcinoma shown by two independent in silico analyses.
Journal: Cancer research 20090501
Title: Transplantation: sirolimus plus calcineurin inhibitors in transplantation.
Journal: Nature reviews. Nephrology 20090501
Title: New oral treatment for kidney cancer approved.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090501
Title: Combination of C-reactive protein and cardiac troponin I for predicting adverse cardiac events after sirolimus-eluting stent implantation.
Journal: Coronary artery disease 20090501
Title: Recent advances in the chemistry, biosynthesis and pharmacology of rapamycin analogs.
Journal: Natural product reports 20090501
Title: Significant response after treatment with the mTOR inhibitor sirolimus in combination with carboplatin and paclitaxel in metastatic melanoma patients.
Journal: Journal of the American Academy of Dermatology 20090501
Title: PTEN deficiency is fully penetrant for prostate adenocarcinoma in C57BL/6 mice via mTOR-dependent growth.
Journal: The American journal of pathology 20090501
Title: Comparison of medium-term outcomes obtained with drug-eluting stents and coronary artery bypass grafts in an unselected population of diabetic patients with multivessel coronary disease. Propensity score analysis.
Journal: Revista espanola de cardiologia 20090501
Title: Beyond monoclonal antibodies: new therapeutic agents in non-Hodgkin's lymphomas.
Journal: The oncologist 20090501
Title: Intravascular ultrasound guidance of multiple drug-eluting stent implantation in lesions associated with coronary aneurysms.
Journal: The Journal of invasive cardiology 20090501
Title: Percutaneous revascularization of chronic total occlusion of left anterior descending artery using contralateral injection via isolated conus artery.
Journal: The Journal of invasive cardiology 20090501
Title: Dual targeting of AKT and mammalian target of rapamycin: a potential therapeutic approach for malignant peripheral nerve sheath tumor.
Journal: Molecular cancer therapeutics 20090501
Title: Xience V everolimus-eluting coronary stent.
Journal: Expert review of medical devices 20090501
Title: Efficacy on renal function of early conversion from cyclosporine to sirolimus 3 months after renal transplantation: concept study.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090501
Title: The applicability of mTOR inhibition in solid tumors.
Journal: Current cancer drug targets 20090501
Title: Atherosclerotic and thrombogenic neointima formed over sirolimus drug-eluting stent: an angioscopic study.
Journal: JACC. Cardiovascular imaging 20090501
Title: One step forward and two steps back with drug-eluting-stents: from preventing restenosis to causing late thrombosis and nouveau atherosclerosis.
Journal: JACC. Cardiovascular imaging 20090501
Title: Prospective clinical trial comparing two immunosuppressive regimens, tacrolimus and mycophenolate mofetil versus everolimus and low-dose cyclosporine, in de novo renal transplant recipients: results at 6 months follow-up.
Journal: Transplantation proceedings 20090501
Title: Cardiovascular risk profile in kidney transplant recipients treated with two immunosuppressive regimens: tacrolimus and mycophenolate mofetil versus everolimus and low-dose cyclosporine.
Journal: Transplantation proceedings 20090501
Title: Immunosuppressive agents and metabolic factors of cardiovascular risk in renal transplant recipients.
Journal: Transplantation proceedings 20090501
Title: Posttransplant proteinuria associated with everolimus.
Journal: Transplantation proceedings 20090501
Title: Immunosuppressive switch to sirolimus in renal dysfunction after liver transplantation.
Journal: Transplantation proceedings 20090501
Title: The impact of everolimus on renal function in maintenance liver transplantation.
Journal: Transplantation proceedings 20090501
Title: Does everolimus associated with a low dose of cyclosporine in long-term cardiac transplant recipients improve renal function? Initial experience.
Journal: Transplantation proceedings 20090501
Title: Rapamycin reduces proteinuria and renal damage in the rat remnant kidney model.
Journal: Transplantation proceedings 20090501
Title: 1-year results of the hydroxyapatite polymer-free sirolimus-eluting stent for the treatment of single de novo coronary lesions: the VESTASYNC I trial.
Journal: JACC. Cardiovascular interventions 20090501
Title: A randomized optical coherence tomography study of coronary stent strut coverage and luminal protrusion with rapamycin-eluting stents.
Journal: JACC. Cardiovascular interventions 20090501
Title: Incomplete stent apposition and delayed tissue coverage are more frequent in drug-eluting stents implanted during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction than in drug-eluting stents implanted for stable/unstable angina: insights from optical coherence tomography.
Journal: JACC. Cardiovascular interventions 20090501
Title: Local determinants of thrombus formation following sirolimus-eluting stent implantation assessed by optical coherence tomography.
Journal: JACC. Cardiovascular interventions 20090501
Title: From a foggy sight to a clear vision.
Journal: JACC. Cardiovascular interventions 20090501
Title: Biodegradable polymer films for releasing nanovehicles containing sirolimus.
Journal: Drug delivery 20090501
Title: [Drug-eluting stents - new standard of restenosis treatment].
Journal: Kardiologia polska 20090501
Title: Combined therapy of CD4(+)CD25(+) regulatory T cells with low-dose sirolimus, but not calcineurin inhibitors, preserves suppressive function of regulatory T cells and prolongs allograft survival in mice.
Journal: International immunopharmacology 20090501
Title: In vitro induced CD4(+)CD25(+)Foxp3(+) Tregs attenuate hepatic ischemia-reperfusion injury.
Journal: International immunopharmacology 20090501
Title: [Intravascular ultrasound assessment of sirolimus-eluting stent restenosis or thrombosis after stent implantation].
Journal: Zhonghua xin xue guan bing za zhi 20090501
Title: Five-year follow-up after sirolimus-eluting stent implantation results of the SIRIUS (Sirolimus-Eluting Stent in De-Novo Native Coronary Lesions) Trial.
Journal: Journal of the American College of Cardiology 20090428
Title: Sirolimus in kidney transplantation indications and practical guidelines: de novo sirolimus-based therapy without calcineurin inhibitors.
Journal: Transplantation 20090427
Title: Sirolimus-based therapy for kidney transplantation from expanded criteria donors.
Journal: Transplantation 20090427
Title: Minimizing the risk of posttransplant malignancy.
Journal: Transplantation 20090427
Title: Management of side effects of sirolimus therapy.
Journal: Transplantation 20090427
Title: Inhibitors of the mammalian target of rapamycin and transplant tolerance.
Journal: Transplantation 20090427
Title: Review of symposium. Sirolimus in kidney transplantation.
Journal: Transplantation 20090427
Title: Protocol conversion from a calcineurin inhibitor based therapy to sirolimus.
Journal: Transplantation 20090427
Title: Rapamycin-eluting stents in the arterial duct: experimental observations in the pig model.
Journal: Circulation 20090421
Title: Focus Issue: demystifying mTOR signaling.
Journal: Science signaling 20090421
Title: The pharmacology of mTOR inhibition.
Journal: Science signaling 20090421
Title: Immune regulation by rapamycin: moving beyond T cells.
Journal: Science signaling 20090421
Title: Frequency, predictors and outcome of stent fracture after sirolimus-eluting stent implantation.
Journal: International journal of cardiology 20090417
Title: Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090415
Title: Efficacy of systemically administered oncolytic vaccinia virotherapy for malignant gliomas is enhanced by combination therapy with rapamycin or cyclophosphamide.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090415
Title: Serial intravascular ultrasound analysis of peri-stent remodeling and proximal and distal edge effects after sirolimus-eluting or paclitaxel-eluting stent implantation in patients with diabetes mellitus.
Journal: The American journal of cardiology 20090415
Title: Activating transcription factor 4 and CCAAT/enhancer-binding protein-beta negatively regulate the mammalian target of rapamycin via Redd1 expression in response to oxidative and endoplasmic reticulum stress.
Journal: Free radical biology & medicine 20090415
Title: Sirolimus to replace calcineurin inhibitors? Too early yet.
Journal: Lancet (London, England) 20090411
Title: Potentiating effects of RAD001 (Everolimus) on vincristine therapy in childhood acute lymphoblastic leukemia.
Journal: Blood 20090402
Title: The role of mTOR in the management of solid tumors: an overview.
Journal: Cancer treatment reviews 20090401
Title: Comparison of changes in early inflammatory markers between sirolimus- and paclitaxel-eluting stent implantation.
Journal: Cardiovascular drugs and therapy 20090401
Title: Safe conversion of mycophenolate mofetil to azathioprine in kidney transplant recipients with sirolimus-based immunosuppression.
Journal: Nephrology (Carlton, Vic.) 20090401
Title: The evaluation of primary stenting of sirolimus-eluting versus bare-metal stents in the treatment of atherosclerotic lesions of crural arteries.
Journal: European radiology 20090401
Title: S6K1 is involved in polyploidization through its phosphorylation at Thr421/Ser424.
Journal: Journal of cellular physiology 20090401
Title: Early systemic inflammatory response to drug-eluting stents implantation: the heart of the difference? Editorial to: 'Comparison of changes in early inflammatory markers between sirolimus- and paclitaxel-eluting stent implantation' by Li et al.
Journal: Cardiovascular drugs and therapy 20090401
Title: Role of the Botrytis cinerea FKBP12 ortholog in pathogenic development and in sulfur regulation.
Journal: Fungal genetics and biology : FG & B 20090401
Title: Rapamycin prevents and breaks the anti-CD3-induced tolerance in NOD mice.
Journal: Diabetes 20090401
Title: Rapamycin reduces seizure frequency in tuberous sclerosis complex.
Journal: Journal of child neurology 20090401
Title: Everolimus and sirolimus antagonize tacrolimus based calcineurin inhibition via competition for FK-binding protein 12.
Journal: Biochemical pharmacology 20090401
Title: Autophagy in coxsackievirus-infected neurons.
Journal: Autophagy 20090401
Title: Relevance of cytotoxic alloreactivity under different immunosuppressive regimens in clinical islet cell transplantation.
Journal: Clinical and experimental immunology 20090401
Title: Uremic cardiac hypertrophy is reversed by rapamycin but not by lowering of blood pressure.
Journal: Kidney international 20090401
Title: The prolyl isomerase Pin1 interacts with a ribosomal protein S6 kinase to enhance insulin-induced AP-1 activity and cellular transformation.
Journal: Carcinogenesis 20090401
Title: Correlation between quantitative angiographic and intravascular ultrasound parameters in patients treated with sirolimus analogous-eluting stents.
Journal: The international journal of cardiovascular imaging 20090401
Title: Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis.
Journal: The Journal of physiology 20090401
Title: Both tacrolimus and sirolimus decrease Th1/Th2 ratio, and increase regulatory T lymphocytes in the liver after ischemia/reperfusion.
Journal: Laboratory investigation; a journal of technical methods and pathology 20090401
Title: Amino acid-sensing mTOR signaling is involved in modulation of lipolysis by chronic insulin treatment in adipocytes.
Journal: American journal of physiology. Endocrinology and metabolism 20090401
Title: PI3K and mTOR inhibitors: a new generation of targeted anticancer agents.
Journal: Current opinion in cell biology 20090401
Title: Treatment with sirolimus results in complete responses in patients with autoimmune lymphoproliferative syndrome.
Journal: British journal of haematology 20090401
Title: Differential control of allo-antigen-specific regulatory T cells and effector T cells by anti-CD4 and other agents in establishing transplantation tolerance.
Journal: International immunology 20090401
Title: Tubers and tumors: rapamycin therapy for benign and malignant tumors.
Journal: Current opinion in cell biology 20090401
Title: A polymer-free dual drug-eluting stent in patients with coronary artery disease: a randomized trial vs. polymer-based drug-eluting stents.
Journal: European heart journal 20090401
Title: Myeloma cell growth inhibition is augmented by synchronous inhibition of the insulin-like growth factor-1 receptor by NVP-AEW541 and inhibition of mammalian target of rapamycin by Rad001.
Journal: Anti-cancer drugs 20090401
Title: Comparison of the systemic levels of inflammatory markers after percutaneous coronary intervention with bare metal versus sirolimus-eluting stents.
Journal: Journal of interventional cardiology 20090401
Title: Repetitive stretch suppresses denervation-induced atrophy of soleus muscle in rats.
Journal: Muscle & nerve 20090401
Title: Targeting mTOR with rapamycin: one dose does not fit all.
Journal: Cell cycle (Georgetown, Tex.) 20090401
Title: Combining sirolimus-eluting stents and external irradiation in cholesterol-fed rabbits increased incomplete stent apposition and decreased re-endothelialization.
Journal: Journal of cardiovascular pharmacology 20090401
Title: Novel neointimal formation over sirolimus-eluting stents identified by coronary angioscopy and optical coherence tomography.
Journal: Journal of cardiology 20090401
Title: A qualitative and quantitative angiographic analysis of stent fracture late following sirolimus-eluting stent implantation.
Journal: The American journal of cardiology 20090401
Title: One-year outcomes from the TAXUS express stent versus cypher stent.
Journal: The American journal of cardiology 20090401
Title: Sirolimus and mTORC1: centre stage in the story of what makes muscles bigger?
Journal: The Journal of physiology 20090401
Title: Management of chronic allograft nephropathy: a systematic review.
Journal: Clinical journal of the American Society of Nephrology : CJASN 20090401
Title: No major neurologic complications with sirolimus use in heart transplant recipients.
Journal: Mayo Clinic proceedings 20090401
Title: The HER-2 receptor and breast cancer: ten years of targeted anti-HER-2 therapy and personalized medicine.
Journal: The oncologist 20090401
Title: Neuroendocrine tumors: nursing implications for oral targeted agents and patient management: Part II.
Journal: Clinical journal of oncology nursing 20090401
Title: Critical role for hypothalamic mTOR activity in energy balance.
Journal: Cell metabolism 20090401
Title: The toxicities of modern targeted therapies: learning from the price of progress.
Journal: Targeted oncology 20090401
Title: Zotarolimus for the treatment of coronary artery disease: pathophysiology, DES design, clinical evaluation and future perspective.
Journal: Expert opinion on pharmacotherapy 20090401
Title: Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition.
Journal: Molecular cancer therapeutics 20090401
Title: Targeting melanoma with dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitors.
Journal: Molecular cancer research : MCR 20090401
Title: Rapamycin protects against high fat diet-induced obesity in C57BL/6J mice.
Journal: Journal of pharmacological sciences 20090401
Title: Prospects for mTOR targeting in adult T cell leukemia.
Journal: Leukemia & lymphoma 20090401
Title: Rapamycin and curcumin induce apoptosis in primary resting B chronic lymphocytic leukemia cells.
Journal: Leukemia & lymphoma 20090401
Title: mTOR inhibition and adult T-cell leukemia.
Journal: Leukemia & lymphoma 20090401
Title: Targeting the mTOR pathway using deforolimus in cancer therapy.
Journal: Future oncology (London, England) 20090401
Title: Hypertension induced by immunosuppressive drugs: a comparative analysis between sirolimus and cyclosporine.
Journal: Transplantation proceedings 20090401
Title: Sirolimus in pediatric liver transplantation: a single-center experience.
Journal: Transplantation proceedings 20090401
Title: Sirolimus-induced drug fever in a renal transplant patient: a case report.
Journal: Transplantation proceedings 20090401
Title: Mucosa-associated lymphoid tissue gastric lymphoma regression in a renal transplant patient after conversion of the immunosuppression to sirolimus: a case report.
Journal: Transplantation proceedings 20090401
Title: Safety of an immunosuppressant protocol based on sirolimus in liver transplant recipients with malignancies or high risk of tumor recurrence.
Journal: Transplantation proceedings 20090401
Title: Right adrenal metastases of hepatocarcinoma after liver transplantation: case report and literature review.
Journal: Transplantation proceedings 20090401
Title: mTOR in renal cell cancer: modulator of tumor biology and therapeutic target.
Journal: Expert review of molecular diagnostics 20090401
Title: Novel side branch ostial stent.
Journal: Journal of interventional cardiology 20090401
Title: [Effect of rapamycin on proliferation, apoptosis and regulation of chemokine receptor CXCR4 in RPMI8226 cells].
Journal: Zhongguo shi yan xue ye xue za zhi 20090401
Title: The emerging safety profile of mTOR inhibitors, a novel class of anticancer agents.
Journal: Targeted oncology 20090401
Title: Drug-eluting stents versus bare-metal stents in diabetic patients with ST-segment elevation acute myocardial infarction: a pooled analysis of individual patient data from seven randomized trials.
Journal: Revista espanola de cardiologia 20090401
Title: RAD001 (Everolimus) Can prevent tamoxifen-related endometrial and stromal hyperplasia.
Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20090401
Title: Rapamycin effects on mTOR signaling in benign, premalignant and malignant human breast epithelial cells.
Journal: Anticancer research 20090401
Title: Treatment for the recurrence of hepatocellular carcinoma following liver transplantation: what is the best strategy?
Journal: Cancer biology & therapy 20090401
Title: Cost-effectiveness of the real-world use of drug-eluting stents at 9-month follow-up: results from the Sicilian DES Registry.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20090401
Title: Lowering the dose of sirolimus, released from a nonpolymeric hydroxyapatite coated coronary stent, reduces signs of delayed healing.
Journal: JACC. Cardiovascular interventions 20090401
Title: Durability of antirestenotic efficacy in drug-eluting stents with and without permanent polymer.
Journal: JACC. Cardiovascular interventions 20090401
Title: Temporal course of neointimal formation after drug-eluting stent placement: is our understanding of restenosis changing?
Journal: JACC. Cardiovascular interventions 20090401
Title: Safety and efficacy of biodegradable polymer-coated sirolimus-eluting stents in 'real-world' practice: 18-month clinical and 9-month angiographic outcomes.
Journal: JACC. Cardiovascular interventions 20090401
Title: The excel stent: a good DES, but can we really stop clopidogrel after 6 months?
Journal: JACC. Cardiovascular interventions 20090401
Title: Rare diseases offer insights into autism spectrum disorders. Preliminary laboratory studies suggest new biological targets for intervention.
Journal: The Harvard mental health letter 20090401
Title: Drug-eluting coronary stents: many meta-analyses, little benefit.
Journal: Prescrire international 20090401
Title: Frequency and clinical consequences associated with sidebranch occlusion during stent implantation using zotarolimus-eluting and paclitaxel-eluting coronary stents.
Journal: Circulation. Cardiovascular interventions 20090401
Title: Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling.
Journal: Molecular cell 20090327
Title: 9-month clinical, angiographic, and intravascular ultrasound results of a prospective evaluation of the Axxess self-expanding biolimus A9-eluting stent in coronary bifurcation lesions: the DIVERGE (Drug-Eluting Stent Intervention for Treating Side Branches Effectively) study.
Journal: Journal of the American College of Cardiology 20090324
Title: Molecular events in the activation of B cells and macrophages by a non-microbial TLR4 agonist, G1-4A from Tinospora cordifolia.
Journal: Immunology letters 20090324
Title: mTORC1 activation regulates beta-cell mass and proliferation by modulation of cyclin D2 synthesis and stability.
Journal: The Journal of biological chemistry 20090320
Title: An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1.
Journal: The Journal of biological chemistry 20090320
Title: Evaluation of neointimal coverage of overlapping sirolimus-eluting stents by optical coherence tomography.
Journal: Chinese medical journal 20090320
Title: Long-term clinical outcomes after bioabsorbable polymer- and durable polymer-based sirolimus-eluting stents implantation: two-year follow-up results from a large single-center database.
Journal: Chinese medical journal 20090320
Title: Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR.
Journal: Science signaling 20090317
Title: Aberrant hyperactivation of akt and Mammalian target of rapamycin complex 1 signaling in sporadic chordomas.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090315
Title: CDC25B mediates rapamycin-induced oncogenic responses in cancer cells.
Journal: Cancer research 20090315
Title: A novel JAK3 inhibitor, R348, attenuates chronic airway allograft rejection.
Journal: Transplantation 20090315
Title: Mycophenolate and sirolimus as calcineurin inhibitor-free immunosuppression improves renal function better than calcineurin inhibitor-reduction in late cardiac transplant recipients with chronic renal failure.
Journal: Transplantation 20090315
Title: A bioabsorbable everolimus-eluting coronary stent system (ABSORB): 2-year outcomes and results from multiple imaging methods.
Journal: Lancet (London, England) 20090314
Title: Clinical outcome of patients with chronic total occlusion treated with drug-eluting stents.
Journal: International journal of cardiology 20090306
Title: S6 kinase 1 regulates estrogen receptor alpha in control of breast cancer cell proliferation.
Journal: The Journal of biological chemistry 20090306
Title: Rapamycin induces transactivation of the EGFR and increases cell survival.
Journal: Oncogene 20090305
Title: Targeting mTOR: something old, something new.
Journal: Journal of the National Cancer Institute 20090304
Title: A randomized comparison of sirolimus- versus paclitaxel-eluting stent implantation in patients with diabetes mellitus 2-year clinical outcomes of the DES-DIABETES trial.
Journal: Journal of the American College of Cardiology 20090303
Title: Nanoscale mechanical measurement determination of the glass transition temperature of poly(lactic acid)/everolimus coated stents in air and dissolution media.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090302
Title: Phosphorylation of p70S6 kinase predicts overall survival in patients with clear margin-resected hepatocellular carcinoma.
Journal: Liver international : official journal of the International Association for the Study of the Liver 20090301
Title: The effect of switching from calcineurin inhibitor to sirolimus on the incidence of skin cancers in kidney transplant recipients.
Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20090301
Title: Activation of interleukin-6/STAT3 in rat cholangiocyte proliferation induced by lipopolysaccharide.
Journal: Digestive diseases and sciences 20090301
Title: A pilot trial of the mTOR (mammalian target of rapamycin) inhibitor RAD001 in patients with advanced B-CLL.
Journal: Annals of hematology 20090301
Title: Sirolimus as a potential radiosensitizer in squamous cell cancer of the head and neck.
Journal: Head & neck 20090301
Title: Negative vascular remodelling after implantation of bioabsorbable magnesium alloy stents in porcine coronary arteries: a randomised comparison with bare-metal and sirolimus-eluting stents.
Journal: Heart (British Cardiac Society) 20090301
Title: Hypersensitivity of Ph-positive lymphoid cell lines to rapamycin: Possible clinical application of mTOR inhibitor.
Journal: Leukemia research 20090301
Title: Liquid chromatographic method for the determination of sirolimus in blood using electrochemical detection.
Journal: Biomedical chromatography : BMC 20090301
Title: A pilot study of everolimus and gefitinib in the treatment of recurrent glioblastoma (GBM).
Journal: Journal of neuro-oncology 20090301
Title: Factors associated with proteinuria in renal transplant recipients treated with sirolimus.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20090301
Title: Conversion to everolimus monotherapy in maintenance liver transplantation: feasibility, safety, and impact on renal function.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20090301
Title: Sirolimus monotherapy effectiveness in liver transplant recipients with renal dysfunction due to calcineurin inhibitors.
Journal: Journal of clinical gastroenterology 20090301
Title: Rapamycin inhibits in vitro growth and release of angiogenetic factors in human bladder cancer.
Journal: Urology 20090301
Title: Nitrogen catabolite repression-sensitive transcription as a readout of Tor pathway regulation: the genetic background, reporter gene and GATA factor assayed determine the outcomes.
Journal: Genetics 20090301
Title: Immunoregulatory profiles in liver transplant recipients on different immunosuppressive agents.
Journal: Human immunology 20090301
Title: Stimulation of skeletal muscle myofibrillar protein synthesis, p70 S6 kinase phosphorylation, and ribosomal protein S6 phosphorylation by inhibition of myostatin in mature mice.
Journal: American journal of physiology. Endocrinology and metabolism 20090301
Title: Angiographic patterns of restenosis after sirolimus-eluting stent implantation.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20090301
Title: Everolimus attenuates neointimal hyperplasia in cultured human saphenous vein grafts.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20090301
Title: Treatment of severe aplastic anemia with a combination of horse antithymocyte globulin and cyclosporine, with or without sirolimus: a prospective randomized study.
Journal: Haematologica 20090301
Title: Combined inhibition of MEK and mTOR signaling inhibits initiation and progression of colorectal cancer.
Journal: Cancer investigation 20090301
Title: Effects of oral posaconazole on the pharmacokinetics of sirolimus.
Journal: Current medical research and opinion 20090301
Title: Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor.
Journal: British journal of pharmacology 20090301
Title: Trypanosome TOR complex 2 functions in cytokinesis.
Journal: Cell cycle (Georgetown, Tex.) 20090301
Title: mTOR inhibitor RAD001 (everolimus) has antiangiogenic/vascular properties distinct from a VEGFR tyrosine kinase inhibitor.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090301
Title: Phospho-p70S6K/p85S6K and cdc2/cdk1 are novel targets for diffuse large B-cell lymphoma combination therapy.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090301
Title: Percutaneous coronary intervention for a right coronary artery stent occlusion using retrograde delivery of a sirolimus-eluting stent via a septal perforator.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090301
Title: Value of drug-eluting stents in cardiac transplant recipients.
Journal: The American journal of cardiology 20090301
Title: Oral rapamycin attenuates inflammation and enhances stability of atherosclerotic plaques in rabbits independent of serum lipid levels.
Journal: British journal of pharmacology 20090301
Title: Determination of blood sirolimus concentrations in liver and kidney transplant recipients using the Innofluor fluorescence polarization immunoassay: comparison with the microparticle enzyme immunoassay and high-performance liquid chromatography-ultraviolet method.
Journal: Upsala journal of medical sciences 20090301
Title: Immunosuppressive treatment for aplastic anemia: are we hitting the ceiling?
Journal: Haematologica 20090301
Title: Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells.
Journal: Nature medicine 20090301
Title: Recommendations from the Spanish Oncology Genitourinary Group for the treatment of metastatic renal cancer.
Journal: Cancer chemotherapy and pharmacology 20090301
Title: ID2-VEGF-related pathways in the pathogenesis of Kaposi's sarcoma: a link disrupted by rapamycin.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090301
Title: Using the stochastic collocation method for the uncertainty quantification of drug concentration due to depot shape variability.
Journal: IEEE transactions on bio-medical engineering 20090301
Title: Recent advances in the systemic treatment of metastatic papillary renal cancer.
Journal: Expert review of anticancer therapy 20090301
Title: Inhibition of Janus kinase 2 and signal transduction and activator of transcription 3 protect against cecal ligation and puncture-induced multiple organ damage and mortality.
Journal: The Journal of trauma 20090301
Title: Drug exposure and perceived adverse drug events reported by liver-transplant patients.
Journal: International journal of clinical pharmacology and therapeutics 20090301
Title: Safety and efficacy of 2.5-mm sirolimus-eluting stent implantation at lower deployment pressures in very small vessels (<2.5 mm).
Journal: Coronary artery disease 20090301
Title: Prolonged dual antiplatelet therapy improves clinical outcomes in high-risk patients implanted with sirolimus-eluting stents.
Journal: Clinical cardiology 20090301
Title: Late conversion from calcineurin inhibitor-based to sirolimus-based immunosuppression due to chronic toxicity: a prospective study with protocol biopsy amendment.
Journal: Transplantation proceedings 20090301
Title: [Prevention of hepatic tumor growth and metastasis in rats with rapamycin].
Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090301
Title: Incidence of stent thrombosis in patients with drug eluting stents and short-term dual antiplatelet therapy.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090301
Title: Re-examining minimal luminal diameter relocation and quantitative coronary angiography--intravascular ultrasound correlations in stented saphenous vein grafts: methodological insights from the randomised RRISC trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090301
Title: Advances in the pathogenesis and treatment of polycystic kidney disease.
Journal: Current opinion in nephrology and hypertension 20090301
Title: Mini-crush versus T-provisional techniques in bifurcation lesions: clinical and angiographic long-term outcome after implantation of drug-eluting stents.
Journal: JACC. Cardiovascular interventions 20090301
Title: [Lymphoproliferative disorders after renal transplantation in a child].
Journal: Revista medica de Chile 20090301
Title: Paclitaxel versus sirolimus stents in diabetic and nondiabetic patients.
Journal: Circulation. Cardiovascular quality and outcomes 20090301
Title: Validation of anti-aging drugs by treating age-related diseases.
Journal: Aging 20090301
Title: Target of rapamycin (TOR) mediates the transduction of nutritional signals into juvenile hormone production.
Journal: The Journal of biological chemistry 20090227
Title: Progression of renal dysfunction in cardiac transplantation after the introduction of everolimus in the immunosuppressive regime.
Journal: Transplantation 20090227
Title: Antiplatelet therapy and stent thrombosis after sirolimus-eluting stent implantation.
Journal: Circulation 20090224
Title: 2-year clinical outcomes after implantation of sirolimus-eluting, paclitaxel-eluting, and bare-metal coronary stents: results from the WDHR (Western Denmark Heart Registry).
Journal: Journal of the American College of Cardiology 20090224
Title: Paclitaxel versus sirolimus: the battle is still ongoing.
Journal: Journal of the American College of Cardiology 20090224
Title: Highly diastereoselective desymmetrisation of cyclic meso-anhydrides and derivatisation for use in natural product synthesis.
Journal: Organic & biomolecular chemistry 20090221
Title: Zebrafish Tsc1 reveals functional interactions between the cilium and the TOR pathway.
Journal: Human molecular genetics 20090215
Title: T cell dependence on mTOR signaling.
Journal: Cell cycle (Georgetown, Tex.) 20090215
Title: Evaluation of mTOR function by a gain-of-function approach.
Journal: Cell cycle (Georgetown, Tex.) 20090215
Title: Marked activity of irinotecan and rapamycin combination toward colon cancer cells in vivo and in vitro is mediated through cooperative modulation of the mammalian target of rapamycin/hypoxia-inducible factor-1alpha axis.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090215
Title: Not all substrates are treated equally: implications for mTOR, rapamycin-resistance and cancer therapy.
Journal: Cell cycle (Georgetown, Tex.) 20090215
Title: Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20090215
Title: Long-term outcomes of left main coronary intervention with drug-eluting stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090215
Title: Long-term clinical outcomes after drug-eluting stent implantation in unprotected left main coronary artery disease.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090215
Title: AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090215
Title: A phase I trial to determine the safety, tolerability, and maximum tolerated dose of deforolimus in patients with advanced malignancies.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090215
Title: Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090211
Title: Delivery of rapamycin to dendritic cells using degradable microparticles.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20090210
Title: Randomized comparison of everolimus-eluting and paclitaxel-eluting stents: two-year clinical follow-up from the Clinical Evaluation of the Xience V Everolimus Eluting Coronary Stent System in the Treatment of Patients with de novo Native Coronary Artery Lesions (SPIRIT) III trial.
Journal: Circulation 20090210
Title: Coronary stent strut fracture after drug-eluting stent implantation: a newly recognized complication.
Journal: International journal of cardiology 20090206
Title: Investigation of the regulation of transcriptional changes in Ancylostoma caninum larvae following serum activation, with a focus on the insulin-like signalling pathway.
Journal: Veterinary parasitology 20090205
Title: Characterization of sirolimus metabolites in pediatric solid organ transplant recipients.
Journal: Pediatric transplantation 20090201
Title: Synthesis of glycose carbamides and evaluation of the induction of erythroid differentiation of human erythroleukemic K562 cells.
Journal: European journal of medicinal chemistry 20090201
Title: Complex functions of phosphatidylinositol 4,5-bisphosphate in regulation of TRPC5 cation channels.
Journal: Pflugers Archiv : European journal of physiology 20090201
Title: Rapamycin in islet transplantation: friend or foe?
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20090201
Title: Adenovirus-mediated FKBP12.6 overexpression induces hypertrophy and apoptosis in cultured neonatal cardiomyocytes.
Journal: Clinical and experimental pharmacology & physiology 20090201
Title: Sirolimus interacts with pathways essential for podocyte integrity.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090201
Title: The pre-clinical assessment of rapamycin-eluting, durable polymer-free stent coating concepts.
Journal: Biomaterials 20090201
Title: Sphingosine-1-phosphate induced mTOR-activation is mediated by the E3-ubiquitin ligase PAM.
Journal: Cellular signalling 20090201
Title: IGF-I, EGF, and sex steroids regulate autophagy in bovine mammary epithelial cells via the mTOR pathway.
Journal: European journal of cell biology 20090201
Title: Activation of the mammalian target of rapamycin signalling pathway in epidermal tumours and its correlation with cyclin-dependent kinase 2.
Journal: The British journal of dermatology 20090201
Title: mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes.
Journal: American journal of physiology. Renal physiology 20090201
Title: Inhibitory effect of rapamycin and dexamethasone on production of IL-17 and IFN-gamma in Vogt-Koyanagi-Harada patients.
Journal: The British journal of ophthalmology 20090201
Title: Everolimus inhibits monocyte/macrophage migration in vitro and their accumulation in carotid lesions of cholesterol-fed rabbits.
Journal: The Journal of pharmacology and experimental therapeutics 20090201
Title: Recent advances in neurobiology of Tuberous Sclerosis Complex.
Journal: Brain & development 20090201
Title: The autophagic induction in Helicobacter pylori-infected macrophage.
Journal: Experimental biology and medicine (Maywood, N.J.) 20090201
Title: Robust, high-throughput LC-MS/MS method for therapeutic drug monitoring of cyclosporine, tacrolimus, everolimus, and sirolimus in whole blood.
Journal: Therapeutic drug monitoring 20090201
Title: Preventing the unfolded protein response via aberrant activation of 4E-binding protein 1 by versipelostatin.
Journal: Cancer science 20090201
Title: mTOR regulates vascular smooth muscle cell differentiation from human bone marrow-derived mesenchymal progenitors.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20090201
Title: Blocking eukaryotic initiation factor 4F complex formation does not inhibit the mTORC1-dependent activation of protein synthesis in cardiomyocytes.
Journal: American journal of physiology. Heart and circulatory physiology 20090201
Title: Impact of a prolonged delivery inflation time for optimal drug-eluting stent expansion.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090201
Title: Targeting heat-shock protein 90 improves efficacy of rapamycin in a model of hepatocellular carcinoma in mice.
Journal: Hepatology (Baltimore, Md.) 20090201
Title: LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection.
Journal: American journal of physiology. Heart and circulatory physiology 20090201
Title: Belatacept as maintenance immunosuppression for postrenal transplant de novo drug-induced thrombotic microangiopathy.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090201
Title: Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathways.
Journal: The FEBS journal 20090201
Title: Pretreatment with insulin before ischaemia reduces infarct size in Langendorff-perfused rat hearts.
Journal: Acta physiologica (Oxford, England) 20090201
Title: Metallothionein: a new soldier in the fight against chronic renal hypoxia?
Journal: Kidney international 20090201
Title: Targeted therapy of human osteosarcoma with 17AAG or rapamycin: characterization of induced apoptosis and inhibition of mTOR and Akt/MAPK/Wnt pathways.
Journal: International journal of oncology 20090201
Title: Laminar and compartmental regulation of dendritic growth in mature cortex.
Journal: Nature neuroscience 20090201
Title: Inflation time and drug-eluting stent: the longer, the better..
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090201
Title: Cost-effectiveness of drug-eluting stents including the economic impact of late stent thrombosis.
Journal: The American journal of cardiology 20090201
Title: Comparison of the sirolimus-eluting versus paclitaxel-eluting coronary stent in patients with diabetes mellitus: the diabetes and drug-eluting stent (DiabeDES) randomized angiography trial.
Journal: The American journal of cardiology 20090201
Title: In early-stage diabetic retinopathy, risk of cardiac events after implantation of sirolimus-eluting stent is higher than after coronary artery bypass surgery.
Journal: Journal of cardiology 20090201
Title: Inhibition of class I phosphoinositide 3-kinase activity impairs proliferation and triggers apoptosis in acute promyelocytic leukemia without affecting atra-induced differentiation.
Journal: Cancer research 20090201
Title: The protein kinase Tor1 regulates adhesin gene expression in Candida albicans.
Journal: PLoS pathogens 20090201
Title: Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.
Journal: PLoS biology 20090201
Title: Common variable immunodeficiency with regulatory T-cell deficiency treated with rapamycin.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20090201
Title: Activation of the AKT and mammalian target of rapamycin pathways and the inhibitory effects of rapamycin on those pathways in canine malignant melanoma cell lines.
Journal: American journal of veterinary research 20090201
Title: Multiple spontaneous coronary artery dissection associated with a left main coronary artery lesion treated by stenting. Late multiple stent fractures detected by multislice CT.
Journal: Revista espanola de cardiologia 20090201
Title: FKBP12 depletion leads to loss of sarcoplasmic reticulum Ca(2+) stores in rat vas deferens.
Journal: Journal of pharmacological sciences 20090201
Title: mTOR-blocking agents in advanced renal cancer: an emerging therapeutic option.
Journal: Expert opinion on investigational drugs 20090201
Title: Interaction with phosphoinositides confers adaptation onto the TRPV1 pain receptor.
Journal: PLoS biology 20090201
Title: Tacrolimus pharmacokinetic drug interactions: effect of prednisone, mycophenolic acid or sirolimus.
Journal: Fundamental & clinical pharmacology 20090201
Title: Optical coherence tomography to diagnose under-expansion of a drug-eluting stent.
Journal: JACC. Cardiovascular imaging 20090201
Title: Clinical and angiographic outcomes with sirolimus-eluting stents in total coronary occlusions: the ACROSS/TOSCA-4 (Approaches to Chronic Occlusions With Sirolimus-Eluting Stents/Total Occlusion Study of Coronary Arteries-4) trial.
Journal: JACC. Cardiovascular interventions 20090201
Title: [The effect of rapamycin liposome gutta inhibiting rat corneal neovascularization].
Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20090201
Title: Randomized comparison of coronary bifurcation stenting with the crush versus the culotte technique using sirolimus eluting stents: the Nordic stent technique study.
Journal: Circulation. Cardiovascular interventions 20090201
Title: Novel role of the CXC chemokine receptor 3 in inflammatory response to arterial injury: involvement of mTORC1.
Journal: Circulation research 20090130
Title: The Rheb-mTOR pathway is upregulated in reactive astrocytes of the injured spinal cord.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090128
Title: Safety and pharmacokinetics of paclitaxel and the oral mTOR inhibitor everolimus in advanced solid tumours.
Journal: British journal of cancer 20090127
Title: Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53.
Journal: British journal of cancer 20090127
Title: What does the CONVERT trial really tell us about conversion from calcineurin inhibitors to sirolimus?
Journal: Transplantation 20090127
Title: Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial.
Journal: Transplantation 20090127
Title: A systematic approach to minimizing wound problems for de novo sirolimus-treated kidney transplant recipients.
Journal: Transplantation 20090127
Title: LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition.
Journal: British journal of cancer 20090127
Title: One year clinical and six month angiographic results of drug eluting stents for ST elevation acute myocardial infarction: 'real world' comparison between sirolimus- and paclitaxel-eluting stents.
Journal: International journal of cardiology 20090124
Title: Rapamycin-induced Gln3 dephosphorylation is insufficient for nuclear localization: Sit4 and PP2A phosphatases are regulated and function differently.
Journal: The Journal of biological chemistry 20090123
Title: [SORT OUT II--a randomized study of drug-eluting coronary stents--secondary publication].
Journal: Ugeskrift for laeger 20090119
Title: Three-year survival following multivessel percutaneous coronary intervention with bare-metal or drug-eluting stents in unselected patients.
Journal: The American journal of cardiology 20090115
Title: Inhibition of mTOR radiosensitizes soft tissue sarcoma and tumor vasculature.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090115
Title: Oral mTOR inhibitor everolimus in patients with gemcitabine-refractory metastatic pancreatic cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090110
Title: Clinical characteristics of stent fracture after sirolimus-eluting stent implantation.
Journal: International journal of cardiology 20090109
Title: Biomedicine. A new view on--and hope for--an old disease.
Journal: Science (New York, N.Y.) 20090109
Title: Biomedicine. A discriminating killer.
Journal: Science (New York, N.Y.) 20090109
Title: New uracil dimers showing erythroid differentiation inducing activities.
Journal: Journal of medicinal chemistry 20090108
Title: Glycemic control in patients with insulinoma treated with everolimus.
Journal: The New England journal of medicine 20090108
Title: Randomized study of the crush technique versus provisional side-branch stenting in true coronary bifurcations: the CACTUS (Coronary Bifurcations: Application of the Crushing Technique Using Sirolimus-Eluting Stents) Study.
Journal: Circulation 20090106
Title: SP600125 negatively regulates the mammalian target of rapamycin via ATF4-induced Redd1 expression.
Journal: FEBS letters 20090105
Title: Rapamycin instead of mycophenolate mofetil or azathioprine in treatment of post-renal transplantation urothelial carcinoma.
Journal: Chinese medical journal 20090105
Title: Clinical outcomes of serolimus-eluting stents versus bare metal stents in ST-segment elevation myocardial infarction patients: a meta-analysis.
Journal: Chinese medical journal 20090105
Title: [Current concepts and treatment advances in systemic mastocytosis].
Journal: La Revue de medecine interne 20090101
Title: Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies.
Journal: Cell death and differentiation 20090101
Title: Moderate-severe renal insufficiency is a risk factor for sirolimus-eluting stent thrombosis. The RIFT study.
Journal: Cardiology 20090101
Title: Multigene targeting of signal transduction pathways for the treatment of breast and prostate tumors: comparison between combination therapies employing bispecific oligonucleotides with either Rapamycin or Paclitaxel.
Journal: Medical oncology (Northwood, London, England) 20090101
Title: Minimization protocols in pancreas transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20090101
Title: Immunosuppression without calcineurin inhibition: optimization of renal function in expanded criteria donor renal transplantation.
Journal: Clinical transplantation 20090101
Title: Metabolic control of T cell activation and death in SLE.
Journal: Autoimmunity reviews 20090101
Title: Steroid withdrawal five days after renal transplantation allows for the prevention of wound-healing complications associated with sirolimus therapy.
Journal: Clinical transplantation 20090101
Title: Influence of HLA disparity, immunosuppressive regimen used, and type of kidney allograft on production of anti-HLA class-I antibodies after transplant and occurrence of rejection.
Journal: Immunopharmacology and immunotoxicology 20090101
Title: Activation of HIF-1alpha in exponentially growing cells via hypoxic stimulation is independent of the Akt/mTOR pathway.
Journal: Journal of cellular physiology 20090101
Title: Different profile of gene expression of cytokines in peripheral blood mononuclear cells of transplant recipients treated with m-TOR inhibitor and calcineurin inhibitor.
Journal: Transplant immunology 20090101
Title: The characteristics and in vivo suppression of neointimal formation with sirolimus-eluting polymeric stents.
Journal: Biomaterials 20090101
Title: The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway.
Journal: Human molecular genetics 20090101
Title: Rapamycin attenuates the severity of murine adriamycin nephropathy.
Journal: American journal of nephrology 20090101
Title: Calcineurin-inhibitor minimization protocols in heart transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20090101
Title: Portal venous donor-specific transfusion in conjunction with sirolimus prolongs renal allograft survival in nonhuman primates.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090101
Title: Mechanisms behind the synergistic effect of sirolimus and imatinib in preventing restenosis after intimal injury.
Journal: Journal of vascular research 20090101
Title: Regulation of placental amino acid transporter activity by mammalian target of rapamycin.
Journal: American journal of physiology. Cell physiology 20090101
Title: Treatment of refractory oral erosive lichen planus with topical rapamycin: 7 cases.
Journal: Dermatology (Basel, Switzerland) 20090101
Title: Significant association of coronary stent fracture with in-stent restenosis in sirolimus-eluting stents.
Journal: Coronary artery disease 20090101
Title: Limited utility of rapamycin in severe, refractory Wegener's granulomatosis.
Journal: The Journal of rheumatology 20090101
Title: Impact of direct sirolimus-eluting stent implantation on the early systemic inflammatory response compared with complementary stent implantation.
Journal: Coronary artery disease 20090101
Title: Use of rapamycin in the induction of tolerogenic dendritic cells.
Journal: Handbook of experimental pharmacology 20090101
Title: Inhibition of human immunodeficiency virus (HIV-1) infection in human peripheral blood leucocytes-SCID reconstituted mice by rapamycin.
Journal: Clinical and experimental immunology 20090101
Title: Three-year clinical outcome after primary stenting of totally occluded native coronary arteries: a randomized comparison of bare-metal stent implantation with sirolimus-eluting stent implantation for the treatment of total coronary occlusions (Primary Stenting of Totally Occluded Native Coronary Arteries [PRISON] II study).
Journal: American heart journal 20090101
Title: Multicenter international registry of unprotected left main coronary artery percutaneous coronary intervention with drug-eluting stents in patients with myocardial infarction.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101
Title: Percutaneous revascularization of the 'unprotected' left main during acute myocardial infarction: 'Dare to struggle! Dare to win!'.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101
Title: Analysis of left main coronary artery bifurcation lesions treated with biolimus-eluting DEVAX AXXESS plus nitinol self-expanding stent: intravascular ultrasound results of the AXXENT trial.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101
Title: Treating the left main bifurcation lesion: the 'three stent solution'.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101
Title: Multiple stent fractures at the site of coronary artery bypass insertion.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101
Title: Coronary stent fracture: the hidden truth of a problem more common than stent thrombosis.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101
Title: Assessment with optical coherence tomography of a new strategy for bifurcational lesion treatment: the Tryton Side-Branch Stent.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101
Title: Step-by-step StentBoost-guided small vessel stenting using the self-expandable Sparrow stent-in-wire.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101
Title: Urine metabolites reflect time-dependent effects of cyclosporine and sirolimus on rat kidney function.
Journal: Chemical research in toxicology 20090101
Title: Sirolimus treatment for recurrent lymphangioleiomyomatosis after lung transplantation.
Journal: The Annals of thoracic surgery 20090101
Title: Characterization of the effects and functions of sumoylation through rapamycin-mediated heterodimerization.
Journal: Methods in molecular biology (Clifton, N.J.) 20090101
Title: San Antonio Breast Cancer Symposium.
Journal: The Lancet. Oncology 20090101
Title: Distinct roles for mammalian target of rapamycin complexes in the fibroblast response to transforming growth factor-beta.
Journal: Cancer research 20090101
Title: Therapeutic strategy targeting the mTOR-HIF-1alpha-VEGF pathway in ovarian clear cell adenocarcinoma.
Journal: Pathology international 20090101
Title: Photodynamic therapy targets the mTOR signaling network in vitro and in vivo.
Journal: Molecular pharmaceutics 20090101
Title: [Effect of Rapamycin and Cyclosporin A on the expression of TLR5 and Foxp3 in allorejection].
Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20090101
Title: Effect of sirolimus on urinary bladder cancer T24 cell line.
Journal: Journal of experimental & clinical cancer research : CR 20090101
Title: Sera from patients with diabetes do not alter the effect of mammalian target of rapamycin inhibition on smooth muscle cell proliferation.
Journal: Journal of cardiovascular pharmacology 20090101
Title: Everolimus-associated pneumonitis in 3 heart transplant recipients.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20090101
Title: Graft-versus-host disease prophylaxis with everolimus and tacrolimus is associated with a high incidence of sinusoidal obstruction syndrome and microangiopathy: results of the EVTAC trial.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090101
Title: Rapamycin for chemoprevention of upper aerodigestive tract cancers.
Journal: Cancer prevention research (Philadelphia, Pa.) 20090101
Title: Targeting mammalian target of rapamycin by rapamycin prevents tumor progression in an oral-specific chemical carcinogenesis model.
Journal: Cancer prevention research (Philadelphia, Pa.) 20090101
Title: Regulation of D-cyclin translation inhibition in myeloma cells treated with mammalian target of rapamycin inhibitors: rationale for combined treatment with extracellular signal-regulated kinase inhibitors and rapamycin.
Journal: Molecular cancer therapeutics 20090101
Title: Bone growth during rapamycin therapy in young rats.
Journal: BMC pediatrics 20090101
Title: mTOR in growth and protection of hypertrophying myocardium.
Journal: Cardiovascular & hematological agents in medicinal chemistry 20090101
Title: Recent patents and patent applications relating to mTOR pathway.
Journal: Recent patents on DNA & gene sequences 20090101
Title: Inhibition of autophagy causes tau proteolysis by activating calpain in rat brain.
Journal: Journal of Alzheimer's disease : JAD 20090101
Title: Conditional nuclear import and export of yeast proteins using a chemical inducer of dimerization.
Journal: Cell biochemistry and biophysics 20090101
Title: The pharmacodynamic effect of sirolimus: individual variation of cytokine mRNA expression profiles in human whole blood samples.
Journal: Immunobiology 20090101
Title: Comparison of bare metal stent with pioglitazone versus sirolimus-eluting stent for percutaneous coronary intervention in patients with Type 2 diabetes mellitus.
Journal: Cardiovascular revascularization medicine : including molecular interventions 20090101
Title: Extremely late drug-eluting stent thrombosis: 2037 days after deployment.
Journal: Cardiovascular revascularization medicine : including molecular interventions 20090101
Title: [Assessment of the course of ischemic heart disease after placement of stents with drug covering and uncovered metal stents: data of 3 years follow-up].
Journal: Kardiologiia 20090101
Title: Temsirolimus in patients with advanced renal cell carcinoma: an overview.
Journal: Advances in therapy 20090101
Title: Metastatic renal cell cancer treatments: an indirect comparison meta-analysis.
Journal: BMC cancer 20090101
Title: [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma].
Journal: Aktuelle Urologie 20090101
Title: Sirolimus-based rescue therapy after rejection in liver transplantation.
Journal: Clinical transplantation 20090101
Title: Cyclosporin A, but not everolimus, inhibits DNA repair in human fibroblasts and lymphoblasts.
Journal: International journal of clinical pharmacology and therapeutics 20090101
Title: Total synthesis of rapamycin.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20090101
Title: Conversion to sirolimus with calcineurin inhibitor elimination vs. dose minimization and renal outcome in heart and lung transplant recipients.
Journal: Clinical transplantation 20090101
Title: [Topics in mTOR pathway and its inhibitors].
Journal: Bulletin du cancer 20090101
Title: Temsirolimus-induced glomerulopathy.
Journal: Oncology 20090101
Title: Phase I study combining treatment with temsirolimus and sunitinib malate in patients with advanced renal cell carcinoma.
Journal: Clinical genitourinary cancer 20090101
Title: Chest pain without significant coronary stenosis after implantation of sirolimus-eluting stents.
Journal: Internal medicine (Tokyo, Japan) 20090101
Title: Effect of temsirolimus versus interferon-alpha on outcome of patients with advanced renal cell carcinoma of different tumor histologies.
Journal: Medical oncology (Northwood, London, England) 20090101
Title: Depletion of kinesin 5B affects lysosomal distribution and stability and induces peri-nuclear accumulation of autophagosomes in cancer cells.
Journal: PloS one 20090101
Title: No in vivo infection of triple immunosuppressed non-human primates after inoculation with high titers of porcine endogenous retroviruses.
Journal: Xenotransplantation 20090101
Title: Survival benefit in heart transplant recipients who have coronary artery disease confirmed using angiography and are receiving sirolimus.
Journal: Transplantation proceedings 20090101
Title: Rapamycin induces autophagy in islets: relevance in islet transplantation.
Journal: Transplantation proceedings 20090101
Title: Effects of systemic immunosuppression on islet engraftment and function into a subcutaneous biocompatible device.
Journal: Transplantation proceedings 20090101
Title: Effect of low-dose rapamycin on tumor growth in two human hepatocellular cancer cell lines.
Journal: Transplantation proceedings 20090101
Title: Effect of liver regeneration on the pharmacokinetics of immunosuppressive drugs.
Journal: Transplantation proceedings 20090101
Title: Rapamycin promotes the enrichment of CD4(+)CD25(hi)FoxP3(+) T regulatory cells from naïve CD4(+) T cells of baboon that suppress antiporcine xenogenic response in vitro.
Journal: Transplantation proceedings 20090101
Title: Sirolimus for rescue of steroid and anti-thymocyte globulin-resistant recurrent acute rejection after liver transplantation: report of one case.
Journal: Transplantation proceedings 20090101
Title: Late conversion to everolimus complicated with necrotizing glomerulonephritis in a renal allograft recipient: case report.
Journal: Transplantation proceedings 20090101
Title: Activated mammalian target of rapamycin is associated with T regulatory cell insufficiency in nasal polyps.
Journal: Respiratory research 20090101
Title: [A case of Kaposi's sarcoma in the rapamycin era].
Journal: Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20090101
Title: Low coronary flow velocity and shear stress predict restenosis after sirolimus-eluting stent implantation.
Journal: Scandinavian cardiovascular journal : SCJ 20090101
Title: Everolimus in liver and lung transplantation.
Journal: Drugs of today (Barcelona, Spain : 1998) 20090101
Title: The gender paradox.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101
Title: Observational studies of drug-eluting stents--some are more equal than others.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101
Title: Assessment of the absorption process following bioabsorbable everolimus-eluting stent implantation: temporal changes in strain values and tissue composition using intravascular ultrasound radiofrequency data analysis. A substudy of the ABSORB clinical trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101
Title: Long-term follow-up of percutaneous coronary intervention of unprotected left main lesions with drug eluting stents: predictors of clinical outcome.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101
Title: The relative safety and efficacy of bare-metal and drug-eluting stents in low and high-risk patient subsets. An epidemiological analysis of three sequential cohorts of consecutive all comers (n = 6129).
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101
Title: Effect of gender differences on early and mid-term clinical outcome after percutaneous or surgical coronary revascularisation in patients with multivessel coronary artery disease: insights from ARTS I and ARTS II.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101
Title: In vivo evaluation of a biolimus eluting nickel titanium self expanding stent with overlapping balloon expandable drug eluting and bare metal stents in a porcine coronary model.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101
Title: Metabolic profiles in urine reflect nephrotoxicity of sirolimus and cyclosporine following rat kidney transplantation.
Journal: Nephron. Experimental nephrology 20090101
Title: Conditional protein stabilization via the small molecules Shld-1 and rapamycin increases the signal-to-noise ratio with tet-inducible gene expression.
Journal: BioTechniques 20090101
Title: Glucose amplifies fatty acid-induced endoplasmic reticulum stress in pancreatic beta-cells via activation of mTORC1.
Journal: PloS one 20090101
Title: A rapid HPLC-MS/MS method for the simultaneous quantification of cyclosporine A, tacrolimus, sirolimus and everolimus in human blood samples.
Journal: Nature protocols 20090101
Title: A central role for Foxp3+ regulatory T cells in K-Ras-driven lung tumorigenesis.
Journal: PloS one 20090101
Title: Testing intravitreal toxicity of rapamycin in rabbit eyes.
Journal: Arquivos brasileiros de oftalmologia 20090101
Title: Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models.
Journal: BMC pharmacology 20090101
Title: Ligand-regulated peptide aptamers.
Journal: Methods in molecular biology (Clifton, N.J.) 20090101
Title: Systemic chemoprevention.
Journal: Cancer treatment and research 20090101
Title: Larger dosage required for everolimus than sirolimus to maintain same blood concentration in two pancreatic islet transplant patients with tacrolimus.
Journal: Drug metabolism and pharmacokinetics 20090101
Title: Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosis.
Journal: The international journal of biochemistry & cell biology 20090101
Title: [Targeting of the AKT-mTOR pathway in head and neck and lung cancer].
Journal: Bulletin du cancer 20090101
Title: Diabetes mellitus: a prothrombotic state implications for outcomes after coronary revascularization.
Journal: Vascular health and risk management 20090101
Title: Interferon-alpha-induced mTOR activation is an anti-hepatitis C virus signal via the phosphatidylinositol 3-kinase-Akt-independent pathway.
Journal: Journal of gastroenterology 20090101
Title: Rapamycin inhibits growth of cholangiocarcinoma cells.
Journal: Hepato-gastroenterology 20090101
Title: A kinase-dead knock-in mutation in mTOR leads to early embryonic lethality and is dispensable for the immune system in heterozygous mice.
Journal: BMC immunology 20090101
Title: Sirolimus-eluting stents or vascular brachytherapy for in-stent restenosis after 3-year follow-up of the SISR (Sirolimus-Eluting Stent Versus Vascular Brachytherapy for In-Stent Restenosis) trial: a call for caution?
Journal: JACC. Cardiovascular interventions 20090101
Title: Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia.
Journal: Disease models & mechanisms 20090101
Title: Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells.
Journal: BMC cancer 20090101
Title: Relationship between renal resistance index and renal function in liver transplant recipients after cessation of calcineurin inhibitor.
Journal: Clinical transplantation 20090101
Title: The influence of commonly used immunosuppressive drugs on the small bowel functions - a comparative experimental study.
Journal: Annals of transplantation 20090101
Title: Current status and challenges associated with targeting mTOR for cancer therapy.
Journal: BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20090101
Title: Management of metabolic cytochrome P450 3A4 drug-drug interaction between everolimus and azole antifungals in a renal transplant patient.
Journal: Clinical drug investigation 20090101
Title: Formalin-induced behavioural hypersensitivity and neuronal hyperexcitability are mediated by rapid protein synthesis at the spinal level.
Journal: Molecular pain 20090101
Title: Different effects of FK506, rapamycin, and mycophenolate mofetil on glucose-stimulated insulin release and apoptosis in human islets.
Journal: Cell transplantation 20090101
Title: Equivalent benefit of mTORC1 blockade and combined PI3K-mTOR blockade in a mouse model of tuberous sclerosis.
Journal: Molecular cancer 20090101
Title: [Long-term results of coronary endovascular revascularisation with sirolimus-eluting stents in patients with ischemic heart disease comorbid with type-2 diabetes mellitus: data from 18-month prospective study].
Journal: Terapevticheskii arkhiv 20090101
Title: Differential responses of human regulatory T cells (Treg) and effector T cells to rapamycin.
Journal: PloS one 20090101
Title: New approach for local delivery of rapamycin by bioadhesive PLGA-carbopol nanoparticles.
Journal: Drug delivery 20090101
Title: Noninvasive evaluation of coronary endothelial function following sirolimus-eluting stent implantation by using positron emission tomography.
Journal: Cardiology 20090101
Title: There is a choice for immunosuppressive drug nephrotoxicity: Is it time to change?
Journal: Journal of nephrology 20090101
Title: Cost effectiveness of sirolimus-eluting stents compared with bare metal stents in acute myocardial infarction: insights from the TYPHOON trial.
Journal: Applied health economics and health policy 20090101
Title: Methods for analysis of brain tumor stem cell and neural stem cell self-renewal.
Journal: Methods in molecular biology (Clifton, N.J.) 20090101
Title: Transport-metabolism interplay: LXRalpha-mediated induction of human ABC transporter ABCC2 (cMOAT/MRP2) in HepG2 cells.
Journal: Molecular pharmaceutics 20090101
Title: Human protein phosphatase PP6 regulatory subunits provide Sit4-dependent and rapamycin-sensitive sap function in Saccharomyces cerevisiae.
Journal: PloS one 20090101
Title: [Economic evaluation and budget impact analysis of the Endeavor drug-eluting stent in Spain].
Journal: Gaceta sanitaria 20090101
Title: Optimizing immunosuppression with sirolimus in the first year posttransplantation: experience in the United States.
Journal: Transplantation proceedings 20090101
Title: Where did we leave off in 2008? Conclusions from the 8th International Symposium.
Journal: Transplantation proceedings 20090101
Title: Reducing the risk of left ventricular hypertrophy in kidney transplant recipients: the potential role of mammalian target of rapamycin.
Journal: Transplantation proceedings 20090101
Title: New approaches to de novo immunosuppression and steroid elimination.
Journal: Transplantation proceedings 20090101
Title: De novo immunosuppression with mammalian target of rapamycin inhibitors and posttransplantation malignancy in focus.
Journal: Transplantation proceedings 20090101
Title: [Association between late incomplete stent apposition after sirolimus eluting stent implantation and clinical outcomes in patients with acute coronary syndrome].
Journal: Zhonghua xin xue guan bing za zhi 20090101
Title: Timing of sirolimus conversion influences recovery of renal function in liver transplant recipients.
Journal: Clinical transplantation 20090101
Title: Combination of everolimus and tacrolimus in kidney transplant patients with intolerance to mycophenolate mofetil/mycophenolic acid.
Journal: Transplantation proceedings 20090101
Title: De novo kidney transplant recipients need higher doses of Advagraf compared with Prograf to get therapeutic levels.
Journal: Transplantation proceedings 20090101
Title: Conversion to everolimus in kidney transplant recipients with decreased renal function.
Journal: Transplantation proceedings 20090101
Title: Evaluation of the efficacy and safety of conversion to sirolimus in 85 renal transplant recipients.
Journal: Transplantation proceedings 20090101
Title: Sirolimus and everolimus induced pneumonitis in adult renal allograft recipients: experience in a center.
Journal: Transplantation proceedings 20090101
Title: Indications and management of everolimus after liver transplantation.
Journal: Transplantation proceedings 20090101
Title: Efficacy, tolerance, and safety of mammalian target of rapamycin inhibitors as rescue immunosuppressants in liver transplantation.
Journal: Transplantation proceedings 20090101
Title: Everolimus represents an advance in immunosuppression for patients who have developed cancer after renal transplantation.
Journal: Transplantation proceedings 20090101
Title: Switching to sirolimus in renal transplant recipients with hepatitis C virus: a safe option.
Journal: Transplantation proceedings 20090101
Title: Similar lipid profile but improved long-term outcomes with sirolimus after cyclosporine withdrawal compared to sirolimus with continuous cyclosporine.
Journal: Transplantation proceedings 20090101
Title: Complete switch to everolimus in long-term kidney transplants: evolution of the renal function.
Journal: Transplantation proceedings 20090101
Title: Clinical implications of proteinuria in renal transplant recipients switching to rapamycin for chronic allograft dysfunction.
Journal: Transplantation proceedings 20090101
Title: Monotherapy rapamycin in renal transplant recipients with lymphoma successfully treated with rituximab.
Journal: Transplantation proceedings 20090101
Title: FTY720 and everolimus in de novo renal transplant patients at risk for delayed graft function: results of an exploratory one-yr multicenter study.
Journal: Clinical transplantation 20090101
Title: Chronic allograft nephropathy--a clinical syndrome: early detection and the potential role of proliferation signal inhibitors.
Journal: Clinical transplantation 20090101
Title: Stent thrombosis four and a half years after implantation of a sirolimus-eluting stent.
Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20090101
Title: Post-transplantation malignancy: a cell autonomous mechanism with implications for therapy.
Journal: Transactions of the American Clinical and Climatological Association 20090101
Title: Interstitial pneumonitis in the transplant patient: consider sirolimus-associated pulmonary toxicity.
Journal: The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society 20090101
Title: The rapamycin-regulated gene expression signature determines prognosis for breast cancer.
Journal: Molecular cancer 20090101
Title: Comparative analysis of neointimal coverage with paclitaxel and zotarolimus drug-eluting stents, using optical coherence tomography 6 months after implantation.
Journal: Archives of cardiovascular diseases 20090101
Title: New therapeutic approaches in the management of metastatic renal cell carcinoma.
Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20090101
Title: Can proliferation signal inhibitor-induced Tregs really reflect transplantation tolerance in clinical solid organ transplantation?
Journal: International reviews of immunology 20090101
Title: Effects of everolimus on cytokines, oxidative stress, and renal histology in ischemia-reperfusion injury of the kidney.
Journal: Renal failure 20090101
Title: Multiple coronary artery aneurysm formation one year and four years after sirolimus-eluting coronary stent implantation.
Journal: Cardiovascular revascularization medicine : including molecular interventions 20090101
Title: Rapamycin response in tumorigenic and non-tumorigenic hepatic cell lines.
Journal: PloS one 20090101
Title: Limited sampling models and Bayesian estimation for mycophenolic acid area under the curve prediction in stable renal transplant patients co-medicated with ciclosporin or sirolimus.
Journal: Clinical pharmacokinetics 20090101
Title: [Pneumonitis caused by sirolimus: improvement after switching to everolimus].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20090101
Title: [The influence of coronary stenting with rapamycin-eluting stents on the number of circulating CD4+CD25high+regulatory T-cells].
Journal: Terapevticheskii arkhiv 20090101
Title: Rapid modification of proteins using a rapamycin-inducible tobacco etch virus protease system.
Journal: PloS one 20090101
Title: Malignant epithelioid angiomyolipoma in the kidney and liver of a patient with pulmonary lymphangioleiomyomatosis: lack of response to sirolimus.
Journal: Internal medicine (Tokyo, Japan) 20090101
Title: Development and characterization of liposomal formulations for rapamycin delivery and investigation of their antiproliferative effect on MCF7 cells.
Journal: Journal of liposome research 20090101
Title: Induction of granzyme B expression in T-cell receptor/CD28-stimulated human regulatory T cells is suppressed by inhibitors of the PI3K-mTOR pathway.
Journal: BMC immunology 20090101
Title: Conversion from cyclosporin A to sirolimus retards the progression of chronic allograft nephropathy in the long term in a rat kidney transplantation model.
Journal: The Journal of international medical research 20090101
Title: mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells.
Journal: Science signaling 20090101
Title: [Acute renal failure in a patient with renal carcinoma treated with temsirolimus].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20090101
Title: Adherence must always be considered: is everolimus really ineffective as a treatment for atopic dermatitis?
Journal: The Journal of dermatological treatment 20090101
Title: Severe atopic dermatitis treated with everolimus.
Journal: The Journal of dermatological treatment 20090101
Title: Repeated plaque prolapse after sirolimus-eluting stent implantation in the treatment of chronic total occlusion lesion.
Journal: Acute cardiac care 20090101
Title: Inhibition of mTOR Activates the MAPK Pathway in Glioblastoma Multiforme.
Journal: Cancer genomics & proteomics 20090101
Title: Controversies in breast cancer: the mammalian target of rapamycin as a target for breast cancer therapy.
Journal: Breast cancer research : BCR 20090101
Title: Update on the everolimus-eluting coronary stent system: results and implications from the SPIRIT clinical trial program.
Journal: Vascular health and risk management 20090101
Title: Combined effect of rapamycin and cisplatin on survival of Hep-2 cells in vitro.
Journal: Oncology research 20090101
Title: Fracture of zotarolimus-eluting stent after implantation.
Journal: Texas Heart Institute journal 20090101
Title: Mycophenolate mofetil versus Rapamycin in Han: SPRD rats with Polycystic Kidney Disease.
Journal: Biological research 20090101
Title: Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density.
Journal: Aging 20090101
Title: Rapamycin does not adversely affect intrahepatic islet engraftment in mice and improves early islet engraftment in humans.
Journal: Islets 20090101
Title: Islet transplantation with alemtuzumab induction and calcineurin-free maintenance immunosuppression results in improved short- and long-term outcomes.
Journal: Transplantation 20081227
Title: Safety and efficacy of statin therapy in patients switched from cyclosporine a to sirolimus after cardiac transplantation.
Journal: Transplantation 20081227
Title: Rapamycin reverses TLR4 signaling-triggered tumor apoptosis resistance by disrupting Akt-mediated Bcl-xL upregulation.
Journal: International immunopharmacology 20081220
Title: Acute coronary syndrome is an independent risk factor for late incomplete stent apposition after sirolimus-eluting stent implantation.
Journal: Chinese medical journal 20081220
Title: Treatment of diffuse in-stent restenosis with drug-eluting stents vs. intracoronary beta-radiation therapy: INDEED Study.
Journal: International journal of cardiology 20081217
Title: Endothelialization and late stent thrombosis in diabetics.
Journal: Journal of the American College of Cardiology 20081216
Title: mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).
Journal: The Biochemical journal 20081215
Title: Mass balance in rapamycin autoxidation.
Journal: Journal of pharmaceutical and biomedical analysis 20081215
Title: Overview of the 2007 Food and Drug Administration Circulatory System Devices Panel meeting on the Xience V Everolimus-Eluting Coronary Stent.
Journal: The American journal of cardiology 20081215
Title: Inhibition of Mammalian target of rapamycin by rapamycin causes the regression of carcinogen-induced skin tumor lesions.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20081215
Title: Deconstructing feedback-signaling networks to improve anticancer therapy with mTORC1 inhibitors.
Journal: Cell cycle (Georgetown, Tex.) 20081215
Title: Differential dependence of hypoxia-inducible factors 1 alpha and 2 alpha on mTORC1 and mTORC2.
Journal: The Journal of biological chemistry 20081212
Title: Improved survival in lymphoma patients receiving sirolimus for graft-versus-host disease prophylaxis after allogeneic hematopoietic stem-cell transplantation with reduced-intensity conditioning.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081210
Title: Multivessel coronary revascularization in patients with and without diabetes mellitus: 3-year follow-up of the ARTS-II (Arterial Revascularization Therapies Study-Part II) trial.
Journal: Journal of the American College of Cardiology 20081209
Title: Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis.
Journal: Cancer cell 20081209
Title: Recovery of tacrolimus-associated brachial neuritis after conversion to everolimus in a pediatric renal transplant recipient--case report and review of the literature.
Journal: Pediatric transplantation 20081201
Title: Involvement of the TGF-beta and mTOR/p70S6Kinase pathways in the transformation process induced by v-ErbA.
Journal: Leukemia research 20081201
Title: Induction of HIF-1alpha expression by intermittent hypoxia: involvement of NADPH oxidase, Ca2+ signaling, prolyl hydroxylases, and mTOR.
Journal: Journal of cellular physiology 20081201
Title: Low viral load post-transplant lymphoproliferative disease localized within the tongue.
Journal: Transplant infectious disease : an official journal of the Transplantation Society 20081201
Title: Sirolimus in unmanipulated haploidentical cell transplantation.
Journal: Bone marrow transplantation 20081201
Title: Rheb activates protein synthesis and growth in adult rat ventricular cardiomyocytes.
Journal: Journal of molecular and cellular cardiology 20081201
Title: Genome-wide expression analysis reveals TORC1-dependent and -independent functions of Sch9.
Journal: FEMS yeast research 20081201
Title: Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury.
Journal: Neurobiology of disease 20081201
Title: Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation.
Journal: Blood 20081201
Title: Blockade of mTOR signaling potentiates the ability of histone deacetylase inhibitor to induce growth arrest and differentiation of acute myelogenous leukemia cells.
Journal: Leukemia 20081201
Title: Exploring the role of novel agents in the treatment of renal cell carcinoma.
Journal: Cancer treatment reviews 20081201
Title: ERK and p38 pathways regulate amino acid signalling.
Journal: Biochimica et biophysica acta 20081201
Title: Phosphorylation of eIF4E by MNKs supports protein synthesis, cell cycle progression and proliferation in prostate cancer cells.
Journal: Carcinogenesis 20081201
Title: Ethylenecarbodiimide-coupled allogeneic antigen presenting cells induce human CD4+ regulatory T cells.
Journal: Clinical immunology (Orlando, Fla.) 20081201
Title: Randomized trial on routine vs. provisional T-stenting in the treatment of de novo coronary bifurcation lesions.
Journal: European heart journal 20081201
Title: The effect of sirolimus on prostate-specific antigen (PSA) levels in male renal transplant recipients without prostate cancer.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20081201
Title: CD8+ T-Cell depletion and rapamycin synergize with combined coreceptor/stimulation blockade to induce robust limb allograft tolerance in mice.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20081201
Title: ABT-869, a multi-targeted tyrosine kinase inhibitor, in combination with rapamycin is effective for subcutaneous hepatocellular carcinoma xenograft.
Journal: Journal of hepatology 20081201
Title: Laryngeal transplantation in the setting of cancer: a rat model.
Journal: The Laryngoscope 20081201
Title: Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase.
Journal: Rapid communications in mass spectrometry : RCM 20081201
Title: Temsirolimus in patients with renal cancer on hemodialysis.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081201
Title: Overcoming mTOR inhibition-induced paradoxical activation of survival signaling pathways enhances mTOR inhibitors' anticancer efficacy.
Journal: Cancer biology & therapy 20081201
Title: Ocular toxicity and distribution of subconjunctival and intravitreal rapamycin in horses.
Journal: Journal of veterinary pharmacology and therapeutics 20081201
Title: Culotte stenting technique in coronary bifurcation disease: angiographic follow-up using dedicated quantitative coronary angiographic analysis and 12-month clinical outcomes.
Journal: European heart journal 20081201
Title: Deforolimus (AP23573) a novel mTOR inhibitor in clinical development.
Journal: Expert opinion on investigational drugs 20081201
Title: Regulation of adiponectin secretion by insulin and amino acids in 3T3-L1 adipocytes.
Journal: Metabolism: clinical and experimental 20081201
Title: The pharmacokinetics of Biolimus A9 after elution from the Nobori stent in patients with coronary artery disease: the NOBORI PK study.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081201
Title: Inhibition of the alloimmune response through the generation of regulatory T cells by a MHC class II-derived peptide.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20081201
Title: CD40-induced signaling in human endothelial cells results in mTORC2- and Akt-dependent expression of vascular endothelial growth factor in vitro and in vivo.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20081201
Title: Insulin-like growth factor stimulation increases radiosensitivity of a pancreatic cancer cell line through endoplasmic reticulum stress under hypoxic conditions.
Journal: Cancer science 20081201
Title: LC3-I conversion to LC3-II does not necessarily result in complete autophagy.
Journal: International journal of molecular medicine 20081201
Title: Is there a preferable DES in diabetic patients? A critical appraisal of the evidence.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081201
Title: Sirolimus ameliorated post lung transplant chylothorax in lymphangioleiomyomatosis.
Journal: The Annals of thoracic surgery 20081201
Title: Treatment for genetic diseases.
Journal: Current opinion in pediatrics 20081201
Title: Incidence of bleeding and compliance on prolonged dual antiplatelet therapy (aspirin + thienopyridine) following drug-eluting stent implantation.
Journal: The American journal of cardiology 20081201
Title: Very late thrombosis of sirolimus-eluting stent due to late malapposition: serial observations with optical coherence tomography.
Journal: Journal of cardiology 20081201
Title: A whole-animal microplate assay for metabolic rate using zebrafish.
Journal: Journal of biomolecular screening 20081201
Title: Autophagy-induced tumor dormancy in ovarian cancer.
Journal: The Journal of clinical investigation 20081201
Title: The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells.
Journal: The Journal of clinical investigation 20081201
Title: Rapamycin shows anticancer activity in primary chronic lymphocytic leukemia cells in vitro, as single agent and in drug combination.
Journal: Leukemia & lymphoma 20081201
Title: Formalin can alter the intracellular localization of some transcription factors in Saccharomyces cerevisiae.
Journal: FEMS yeast research 20081201
Title: Endothelialization of sirolimus-eluting stents with slow and extended drug release in the porcine overstretch model.
Journal: The Journal of invasive cardiology 20081201
Title: Proliferation signal inhibitor-induced decrease of vascular endothelial cadherin expression and increase of endothelial permeability in vitro are prevented by an anti-oxidant.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20081201
Title: Epstein-Barr virus, rapamycin, and host immune responses.
Journal: Current opinion in organ transplantation 20081201
Title: In vivo characterization of a polymeric nanoparticle platform with potential oral drug delivery capabilities.
Journal: Molecular cancer therapeutics 20081201
Title: Re: 'midterm results of a sirolimus-eluting stent implanted for recurrent carotid in-stent restenosis'.
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20081201
Title: [Everolimus (RAD001) and solid tumours: a 2008 summary].
Journal: Bulletin du cancer 20081201
Title: Therapeutic effect of Tripterygium wilfordii on proteinuria associated with sirolimus in renal transplant recipients.
Journal: Transplantation proceedings 20081201
Title: Sirolimus-based immunosuppression therapy in liver transplantation for patients with hepatocellular carcinoma exceeding the Milan criteria.
Journal: Transplantation proceedings 20081201
Title: Conversion to sirolimus in kidney-pancreas and pancreas transplantation.
Journal: Transplantation proceedings 20081201
Title: A combination of donor specific transfusion and rapamycin prolongs cardiac allograft survival in mice.
Journal: Transplantation proceedings 20081201
Title: Treatment of chronic allograft nephropathy at late stages using everolimus or FTY720 in combination with cyclosporine.
Journal: Transplantation proceedings 20081201
Title: Severe sirolimus-related inflammatory state anemia in an HIV+ liver transplant patient with calcineurin inhibitor renal insufficiency: a case report.
Journal: Transplantation proceedings 20081201
Title: Fifteen years of clinical studies and clinical practice in renal transplantation: reviewing outcomes with de novo use of sirolimus in combination with cyclosporine.
Journal: Transplantation proceedings 20081201
Title: Modern approaches to combining sirolimus with calcineurin inhibitors.
Journal: Transplantation proceedings 20081201
Title: Reviewing the evidence for de novo immunosuppression with sirolimus.
Journal: Transplantation proceedings 20081201
Title: Optimizing early de novo immunosuppression with sirolimus.
Journal: Transplantation proceedings 20081201
Title: The impact of mTOR inhibitors on the development of malignancy.
Journal: Transplantation proceedings 20081201
Title: Temsirolimus in renal cell carcinoma.
Journal: Transplantation proceedings 20081201
Title: Minimizing the risk of posttransplant malignancy.
Journal: Transplantation proceedings 20081201
Title: New approaches to de novo immunosuppression and steroid elimination.
Journal: Transplantation proceedings 20081201
Title: Stratifying risk and targeting immunosuppressive strategies.
Journal: Transplantation proceedings 20081201
Title: Treatment of saphenous vein graft lesions with paclitaxel- and sirolimus-eluting stents: comparison of short- and long-term clinical outcomes.
Journal: Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20081201
Title: Rapamycin inhibits growth factor-induced cell cycle regulation in pancreatic beta cells.
Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20081201
Title: [Outcome of patients implanted with bioabsorbable polymer sirolimus-eluting stent (Excel) and the durable polymer sirolimus-eluting stent (Cypher)].
Journal: Zhonghua xin xue guan bing za zhi 20081201
Title: Comparison of vasa vasorum after intravascular stent placement with sirolimis drug-eluting and bare metal stents.
Journal: Journal of medical imaging and radiation oncology 20081201
Title: Effects of rapamycin on intracellular cholesterol homeostasis of glomerular mesangial cell in the presence of interleukin-1 beta.
Journal: Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20081201
Title: [Expression of mammalian target of rapamycin and p70 S6 kinase in rabbit periodontal tissues remodeling during orthodontic tooth movement].
Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20081201
Title: Temsirolimus: new drug. Metastatic kidney cancer: more assessment needed.
Journal: Prescrire international 20081201
Title: Common corruption of the mTOR signaling network in human tumors.
Journal: Oncogene 20081201
Title: Interference of drug-eluting stents with endothelium-dependent coronary vasomotion: evidence for device-specific responses.
Journal: Circulation. Cardiovascular interventions 20081201
Title: Inhibition of apoptosis through localized delivery of rapamycin-loaded nanoparticles prevented neointimal hyperplasia and reendothelialized injured artery.
Journal: Circulation. Cardiovascular interventions 20081201
Title: Regulation of androgen receptor transcriptional activity by rapamycin in prostate cancer cell proliferation and survival.
Journal: Oncogene 20081127
Title: Sirolimus as primary immunosuppressant reduces left ventricular mass and improves diastolic function of the cardiac allograft.
Journal: Transplantation 20081127
Title: Comparison of sirolimus plus tacrolimus versus sirolimus plus cyclosporine in high-risk renal allograft recipients: results from an open-label, randomized trial.
Journal: Transplantation 20081115
Title: Susceptibility of human mesenchymal stem cells to tacrolimus, mycophenolic acid, and rapamycin.
Journal: Transplantation 20081115
Title: Effects of immunosuppressive drugs on purified human B cells: evidence supporting the use of MMF and rapamycin.
Journal: Transplantation 20081115
Title: Serial angiographic and intravascular ultrasound analysis of late stent strut fracture of sirolimus-eluting stents in native coronary arteries.
Journal: International journal of cardiology 20081112
Title: Fracture of a sirolimus-eluting stent with migration.
Journal: International journal of cardiology 20081112
Title: Thrombus causes fluctuations in arterial drug delivery from intravascular stents.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20081112
Title: Late stent recoil of the bioabsorbable everolimus-eluting coronary stent and its relationship with plaque morphology.
Journal: Journal of the American College of Cardiology 20081111
Title: Long-term clinical benefit of sirolimus-eluting stents in patients with in-stent restenosis results of the RIBS-II (Restenosis Intra-stent: Balloon angioplasty vs. elective sirolimus-eluting Stenting) study.
Journal: Journal of the American College of Cardiology 20081111
Title: A mathematical model for predicting drug release from a biodurable drug-eluting stent coating.
Journal: Journal of biomedical materials research. Part A 20081101
Title: Tacrolimus withdrawal and conversion to sirolimus at three months post-pediatric renal transplantation.
Journal: Pediatric transplantation 20081101
Title: Dopaminergic modulation of auditory cortex-dependent memory consolidation through mTOR.
Journal: Cerebral cortex (New York, N.Y. : 1991) 20081101
Title: Cyclin B synthesis and rapamycin-sensitive regulation of protein synthesis during starfish oocyte meiotic divisions.
Journal: Molecular reproduction and development 20081101
Title: [Primary chronic autoimmune neutropenia successfully treated with sirolimus].
Journal: La Revue de medecine interne 20081101
Title: Reactive oxygen species in tumor necrosis factor-alpha-activated primary human keratinocytes: implications for psoriasis and inflammatory skin disease.
Journal: The Journal of investigative dermatology 20081101
Title: mTOR mediates survival signals in malignant mesothelioma grown as tumor fragment spheroids.
Journal: American journal of respiratory cell and molecular biology 20081101
Title: Conversion to sirolimus for chronic renal allograft dysfunction: risk factors for graft loss and severe side effects.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081101
Title: Restoration of renal function in zebrafish models of ciliopathies.
Journal: Pediatric nephrology (Berlin, Germany) 20081101
Title: Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism.
Journal: Amino acids 20081101
Title: Dentritic cell derived IL-18 production is inhibited by rapamycin and sanglifehrin A, but not cyclosporine A.
Journal: Transplant immunology 20081101
Title: Differential promotion of hematopoietic chimerism and inhibition of alloreactive T cell proliferation by combinations of anti-CD40Ligand, anti-LFA-1, everolimus, and deoxyspergualin.
Journal: Transplant immunology 20081101
Title: Rapamycin reverses NPM-ALK-induced glucocorticoid resistance in lymphoid tumor cells by inhibiting mTOR signaling pathway, enhancing G1 cell cycle arrest and apoptosis.
Journal: Leukemia 20081101
Title: [Molecular basis of targeted therapy in metastatic renal cancer].
Journal: Der Pathologe 20081101
Title: Rapamycin does not improve insulin sensitivity despite elevated mammalian target of rapamycin complex 1 activity in muscles of ob/ob mice.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20081101
Title: Comparison of four different immunosuppression protocols without long-term steroid therapy in kidney recipients monitored by surveillance biopsy: five-year outcomes.
Journal: Transplant immunology 20081101
Title: Sirolimus affects cardiomyocytes to reduce left ventricular mass in heart transplant recipients.
Journal: European heart journal 20081101
Title: Sirolimus-based, calcineurin-inhibitor sparing immunotherapy, long-term (6-year) results.
Journal: Transplant immunology 20081101
Title: Prolonged insulin independence after islet allotransplants in recipients with type 1 diabetes.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20081101
Title: Pharmacokinetic interaction between everolimus and antifungal triazoles in a liver transplant patient.
Journal: The Annals of pharmacotherapy 20081101
Title: Targeting the mammalian target of rapamycin in myxoid chondrosarcoma.
Journal: Anti-cancer drugs 20081101
Title: Neointimal hyperplasia after sirolimus-eluting and paclitaxel-eluting stent implantation in diabetic patients: the Randomized Diabetes and Drug-Eluting Stent (DiabeDES) Intravascular Ultrasound Trial.
Journal: European heart journal 20081101
Title: [Myocardial revascularization: the point in 2008].
Journal: Presse medicale (Paris, France : 1983) 20081101
Title: Immediate and long-term results of treatment of complex lesions of the left anterior descending coronary artery involving a large diagonal branch with drug-eluting stents.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20081101
Title: Switch of immunosuppression from cyclosporine A to everolimus: impact on pulse wave velocity in stable de-novo renal allograft recipients.
Journal: Journal of hypertension 20081101
Title: Mechanism of action of rapalogues: the antiangiogenic hypothesis.
Journal: Expert opinion on investigational drugs 20081101
Title: Drug-eluting stents for the treatment of ostial coronary lesions: comparison of sirolimus-eluting stent with paclitaxel-eluting stent.
Journal: Coronary artery disease 20081101
Title: Minimization of immunosuppression: transplant immunology.
Journal: Transplant immunology 20081101
Title: Sirolimus treatment of left ventricular hypertrophy: who, and when?
Journal: European heart journal 20081101
Title: Comparison of sirolimus-eluting stent and paclitaxel-eluting stent for long-term cardiac adverse events in diabetic patients: the Korean Multicenter Angioplasty Team (KOMATE) Registry.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081101
Title: Clinical presentation of patients with late target lesion revascularization.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081101
Title: Growth stimulation leads to cellular senescence when the cell cycle is blocked.
Journal: Cell cycle (Georgetown, Tex.) 20081101
Title: A randomized comparison of sirolimus-eluting versus bare metal stents in the treatment of diabetic patients with native coronary artery lesions: the DECODE study.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081101
Title: Regression of pulmonary lymphangioleiomyomatosis (PLAM)-associated retroperitoneal angiomyolipoma post-lung transplantation with rapamycin treatment.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20081101
Title: Gingival status of Brazilian renal transplant recipients under sirolimus-based regimens.
Journal: Journal of periodontology 20081101
Title: Intractable Prinzmetal's angina three months after implantation of sirolimus-eluting stent.
Journal: The Journal of invasive cardiology 20081101
Title: Systemic immunosuppressive therapy with oral Sirolimus after bare metal stent implantation: the missing alternative in the prevention of coronary restenosis after percutaneous coronary interventions.
Journal: Recent patents on cardiovascular drug discovery 20081101
Title: Systemic therapy for metastatic renal cell carcinoma.
Journal: The Urologic clinics of North America 20081101
Title: [Treatment of drug-eluting stent restenosis with another drug-eluting stent: do not fail the second time!].
Journal: Revista espanola de cardiologia 20081101
Title: [Treatment of Paclitaxel-eluting stent restenosis with sirolimus-eluting stent implantation: angiographic and clinical outcomes].
Journal: Revista espanola de cardiologia 20081101
Title: [67-year-old patient with speech disorder and dysphagia].
Journal: Deutsche medizinische Wochenschrift (1946) 20081101
Title: Tolerance profile of the proliferation signal inhibitors everolimus and sirolimus in heart transplantation.
Journal: Transplantation proceedings 20081101
Title: Preliminary experience with conversion from calcineurin inhibitors to everolimus in cardiac transplantation maintenance therapy.
Journal: Transplantation proceedings 20081101
Title: Conversion to rapamycin in a renal transplant patient with von Hippel-Lindau disease: encouraging results-a case report.
Journal: Transplantation proceedings 20081101
Title: Use of everolimus in de novo renal recipients: initial experience in the Greek population.
Journal: Transplantation proceedings 20081101
Title: Metabolic changes following conversion from an anticalcineurin-based therapy to an everolimus-based one: a single-center experience.
Journal: Transplantation proceedings 20081101
Title: Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration.
Journal: Cell metabolism 20081101
Title: [Oral ulcers in kidney allograft recipients treated with sirolimus].
Journal: Annales de dermatologie et de venereologie 20081101
Title: Percutaneous coronary implantation of sirolimus-eluting stents in unselected patients and lesions: clinical results and multiple outcome predictors.
Journal: American heart journal 20081101
Title: Long-term coronary endothelial function after zotarolimus-eluting stent implantation. A 9 month comparison between zotarolimus-eluting and sirolimus-eluting stents.
Journal: International heart journal 20081101
Title: Four-year safety and efficacy of the unrestricted use of sirolimus- and paclitaxel-eluting stents in coronary artery bypass grafts.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20081101
Title: Very late thrombosis in acute myocardial infarction: drug-eluting versus uncoated stents.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20081101
Title: Long-term safety and efficacy are observed after implantation of Zotarolimus-Eluting stent in real-world clinical practice.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20081101
Title: [Benefit-risk ratio of coronary drug-eluting stents: 2nd part: evaluation in the diabetic population].
Journal: Revue medicale de Liege 20081101
Title: The changing face of angiographic patterns of restenosis after drug-eluting stent placement: sirolimus versus paclitaxel-eluting stent.
Journal: International journal of cardiology 20081030
Title: Simultaneous subacute stent thrombosis of two sirolimus-eluting stents in a patient treated by ReoPro, thrombus aspiration and triple anti-platelet agents.
Journal: International journal of cardiology 20081030
Title: Rapamycin downregulates the inhibitory receptors ILT2, ILT3, ILT4 on human dendritic cells and yet induces T cell hyporesponsiveness independent of FoxP3 induction.
Journal: Immunology letters 20081030
Title: One year follow-up of steroid-free immunosuppression plus everolimus in isolated pancreas transplantation.
Journal: Transplantation 20081027
Title: mTORC1 inhibitors: is temsirolimus in renal cancer telling us how they really work?
Journal: British journal of cancer 20081021
Title: [Effects of constant magnetic fields on proliferation and migration of endothelial progenitor cells under rapamycin intervention: experiment with rats].
Journal: Zhonghua yi xue za zhi 20081021
Title: [Sirolimus inhibits the expression of type I collagen and fibronectin in cultured renal cortical myofibroblasts].
Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20081018
Title: Metabolic stress induces the lysosomal degradation of neuropilin-1 but not neuropilin-2.
Journal: The Journal of biological chemistry 20081017
Title: Melatonin prevents ischemic brain injury through activation of the mTOR/p70S6 kinase signaling pathway.
Journal: Neuroscience letters 20081017
Title: The TSC-mTOR signaling pathway regulates the innate inflammatory response.
Journal: Immunity 20081017
Title: Dual inhibition of PI3Kalpha and mTOR as an alternative treatment for Kaposi's sarcoma.
Journal: Cancer research 20081015
Title: Shp2 negatively regulates growth in cardiomyocytes by controlling focal adhesion kinase/Src and mTOR pathways.
Journal: Circulation research 20081010
Title: Very late stent fracture associated with a sirolimus-eluting stent.
Journal: Heart, lung & circulation 20081001
Title: An investigation of adhesion in drug-eluting stent layers.
Journal: Journal of biomedical materials research. Part A 20081001
Title: Lack of antileukemic activity of rapamycin in elderly patients with acute myeloid leukemia evolving from a myelodysplastic syndrome.
Journal: Leukemia research 20081001
Title: Sirolimus reduces the incidence and progression of UVB-induced skin cancer in SKH mice even with co-administration of cyclosporine A.
Journal: The Journal of investigative dermatology 20081001
Title: Different renal toxicity profiles in the association of cyclosporine and tacrolimus with sirolimus in rats.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081001
Title: Thrombin induces osteoprotegerin synthesis via phosphatidylinositol 3'-kinase/mammalian target of rapamycin pathway in human periodontal ligament cells.
Journal: Journal of periodontal research 20081001
Title: [Value of targeted therapy for prostate cancer].
Journal: Der Urologe. Ausg. A 20081001
Title: [Value of targeted therapies for renal cell cancer].
Journal: Der Urologe. Ausg. A 20081001
Title: Effects of peroxisome proliferator-activated receptor alpha (PPARalpha) agonists on leucine-induced phosphorylation of translational targets in C2C12 cells.
Journal: Biochimica et biophysica acta 20081001
Title: Mechanisms of Disease: survival benefit of temsirolimus validates a role for mTOR in the management of advanced RCC.
Journal: Nature clinical practice. Oncology 20081001
Title: Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1.
Journal: Human molecular genetics 20081001
Title: Phospho-proteomic approach to identify new targets of leucine deprivation in muscle cells.
Journal: Analytical biochemistry 20081001
Title: Simultaneous islet and kidney transplantation in seven patients with type 1 diabetes and end-stage renal disease using a glucocorticoid-free immunosuppressive regimen with alemtuzumab induction.
Journal: Diabetes 20081001
Title: Randomized comparison of early inflammatory response after sirolimus-eluting stent vs bare metal stent implantation in native coronary lesions.
Journal: Clinica chimica acta; international journal of clinical chemistry 20081001
Title: Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement.
Journal: Neurobiology of disease 20081001
Title: Prolonged response to temsirolimus in a pre-treated patient with metastatic renal cell carcinoma and poor performance status.
Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20081001
Title: Kaposi sarcoma in transplantation.
Journal: Transplantation reviews (Orlando, Fla.) 20081001
Title: Effect of mTOR inhibitor on body weight: from an experimental rat model to human transplant patients.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20081001
Title: Severe everolimus-associated pneumonitis in a renal transplant recipient.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081001
Title: Bioabsorbable drug-eluting stents: the future of coronary angioplasty?
Journal: Nature clinical practice. Cardiovascular medicine 20081001
Title: Leucine stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing mTORC1 activation.
Journal: American journal of physiology. Endocrinology and metabolism 20081001
Title: [Targeted therapy - point blank or single shot].
Journal: Der Urologe. Ausg. A 20081001
Title: Prolongation of corneal allograft survival by topical application of everolimus in experimental keratoplasty.
Journal: Ophthalmic research 20081001
Title: Everolimus- and zotarolimus-eluting stents for bare metal stent in-stent restenosis treatment: a prospective study.
Journal: Journal of interventional cardiology 20081001
Title: Morphological and biochemical characterization of basal and starvation-induced autophagy in isolated adult rat cardiomyocytes.
Journal: American journal of physiology. Heart and circulatory physiology 20081001
Title: Impact of current transplantation management on the development of cytomegalovirus disease after renal transplantation.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20081001
Title: TOR regulates the subcellular distribution of DIM2, a KH domain protein required for cotranscriptional ribosome assembly and pre-40S ribosome export.
Journal: RNA (New York, N.Y.) 20081001
Title: Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway.
Journal: Nature immunology 20081001
Title: Prevention of cancer by inhibiting aging.
Journal: Cancer biology & therapy 20081001
Title: Persistent clinical impact of cytomegalovirus in organ transplantation.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20081001
Title: Sirolimus: a potential chemopreventive agent.
Journal: The Journal of investigative dermatology 20081001
Title: Insulin induces monocytic CXCL8 secretion by the mitogenic signalling pathway.
Journal: Cytokine 20081001
Title: Impact of mammalian target of rapamycin inhibition on lymphoid homing and tolerogenic function of nanoparticle-labeled dendritic cells following allogeneic hematopoietic cell transplantation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20081001
Title: Suboptimal percutaneous coronary intervention.
Journal: The American journal of cardiology 20081001
Title: Prognostic value of lesion classification for the clinical outcome after stent placement.
Journal: The American journal of cardiology 20081001
Title: Novel drugs for renal cell carcinoma.
Journal: Expert opinion on investigational drugs 20081001
Title: Complete versus incomplete revascularization in patients with multivessel disease undergoing percutaneous coronary intervention with drug-eluting stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081001
Title: Sirolimus-eluting stents versus bare-metal stents in patients with in-stent restenosis: results of a pooled analysis of two randomized studies.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081001
Title: Letter by Kounis et al regarding article, 'sirolimus-eluting stents suppress neointimal formation irrespective of metallic allergy'.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20081001
Title: 'Neither horseshoes nor hand grenades'--does close count in percutaneous coronary revascularization?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081001
Title: Repetita iuvant.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081001
Title: [Systemic therapy of metastasizing renal cell carcinoma].
Journal: Der Urologe. Ausg. A 20081001
Title: Recent advances in the treatment of renal cell carcinoma and the role of targeted therapies.
Journal: European journal of cancer (Oxford, England : 1990) 20081001
Title: Unprotected left main coronary artery bifurcation stenosis: impact of plaque debulking prior to single sirolimus-eluting stent implantation.
Journal: The Journal of invasive cardiology 20081001
Title: [Recent therapeutic progress in non-Hodgkin lymphoma: focusing on diffuse large B-cell lymphoma and follicular lymphoma].
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20081001
Title: Targeted therapies for metastatic renal cell carcinoma: an overview of toxicity and dosing strategies.
Journal: The oncologist 20081001
Title: Robust and systematic drug screening method using chemical arrays and the protein library: identification of novel inhibitors of carbonic anhydrase II.
Journal: Bioscience, biotechnology, and biochemistry 20081001
Title: ABT-263 and rapamycin act cooperatively to kill lymphoma cells in vitro and in vivo.
Journal: Molecular cancer therapeutics 20081001
Title: Size matters (but so does time), and it's OK to be different.
Journal: Developmental cell 20081001
Title: The TOR pathway couples nutrition and developmental timing in Drosophila.
Journal: Developmental cell 20081001
Title: Systemic exposure of everolimus after stent implantation: a pharmacokinetic study.
Journal: American heart journal 20081001
Title: Avoidance of calcineurin inhibitors with use of proliferation signal inhibitors in de novo heart transplantation with renal failure.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20081001
Title: Heart transplantation under cyclosporine or tacrolimus combined with mycophenolate mofetil or everolimus.
Journal: Transplantation proceedings 20081001
Title: Rapamycin-induced cytotoxic signal transduction pathway.
Journal: Transplantation proceedings 20081001
Title: Rapamycin and cyclosporine have different effects on expression of Ang-1 and Ang-2 and Tie2 in rat renal allograft with chronic allograft nephropathy.
Journal: Transplantation proceedings 20081001
Title: Sirolimus-eluting and paclitaxel-eluting stents for the treatment of coronary bifurcations.
Journal: American heart journal 20081001
Title: Regression of subependymal giant cell astrocytoma with rapamycin in tuberous sclerosis complex.
Journal: Journal of child neurology 20081001
Title: [Effect of chemotherapy with cisplatin and rapamycin against Hep-2 cells in vitro].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20081001
Title: Combination treatment with plasmapheresis and sirolimus does not seem to benefit nephrogenic systemic fibrosis.
Journal: The International journal of artificial organs 20081001
Title: mTOR inhibition reverses acquired endocrine therapy resistance of breast cancer cells at the cell proliferation and gene-expression levels.
Journal: Cancer science 20081001
Title: Status of drug-eluting coronary stents.
Journal: Medicine and health, Rhode Island 20081001
Title: Out with the old, in with the new: immunosuppression minimization in children.
Journal: Current opinion in organ transplantation 20081001
Title: Therapies for interstitial lung disease: past, present and future.
Journal: Therapeutic advances in respiratory disease 20081001
Title: [Blockage of mTOR signaling pathway by rapamycin contributes to inhibition of tumor cell proliferation in ALK-positive lymphoid cell strains].
Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20081001
Title: A randomized, controlled, multicenter trial to evaluate the safety and efficacy of zotarolimus- versus paclitaxel-eluting stents in de novo occlusive lesions in coronary arteries The ZoMaxx I trial.
Journal: JACC. Cardiovascular interventions 20081001
Title: The process of bringing new drug-eluting stents to market will they see the light of day?
Journal: JACC. Cardiovascular interventions 20081001
Title: Differential healing responses in polymer- and nonpolymer-based sirolimus-eluting stents.
Journal: JACC. Cardiovascular interventions 20081001
Title: Preliminary results of the hydroxyapatite nonpolymer-based sirolimus-eluting stent for the treatment of single de novo coronary lesions a first-in-human analysis of a third-generation drug-eluting stent system.
Journal: JACC. Cardiovascular interventions 20081001
Title: Tissue sirolimus levels of distal vessel, stented myocardium, and distal myocardium.
Journal: JACC. Cardiovascular interventions 20081001
Title: Primary percutaneous coronary intervention with drug-eluting stents: another chapter in the stent controversy.
Journal: Circulation. Cardiovascular interventions 20081001
Title: Primary percutaneous coronary intervention for acute myocardial infarction: long-term outcome after bare metal and drug-eluting stent implantation.
Journal: Circulation. Cardiovascular interventions 20081001
Title: Incidence and correlates of drug-eluting stent thrombosis in routine clinical practice. 4-year results from a large 2-institutional cohort study.
Journal: Journal of the American College of Cardiology 20080930
Title: Biolimus-eluting stent with biodegradable polymer versus sirolimus-eluting stent with durable polymer for coronary revascularisation (LEADERS): a randomised non-inferiority trial.
Journal: Lancet (London, England) 20080927
Title: Drug-eluting stents: is new necessarily better?
Journal: Lancet (London, England) 20080927
Title: Calcineurin inhibitor sparing in renal transplantation.
Journal: Transplantation 20080927
Title: The anchor-away technique: rapid, conditional establishment of yeast mutant phenotypes.
Journal: Molecular cell 20080926
Title: Angioscopic findings of delayed healing at sites of sirolimus-eluting stent overlap after 21-month implantation.
Journal: International journal of cardiology 20080916
Title: Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation.
Journal: Blood 20080915
Title: Defects in skin gamma delta T cell function contribute to delayed wound repair in rapamycin-treated mice.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20080915
Title: Safety of drug-eluting stents in patients with left ventricular dysfunction undergoing percutaneous coronary intervention.
Journal: The American journal of cardiology 20080915
Title: Enhancing mammalian target of rapamycin (mTOR)-targeted cancer therapy by preventing mTOR/raptor inhibition-initiated, mTOR/rictor-independent Akt activation.
Journal: Cancer research 20080915
Title: FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression.
Journal: Science (New York, N.Y.) 20080912
Title: Efficacy of RAD001 (everolimus) and octreotide LAR in advanced low- to intermediate-grade neuroendocrine tumors: results of a phase II study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080910
Title: Rapamycin down-regulates LDL-receptor expression independently of SREBP-2.
Journal: Biochemical and biophysical research communications 20080905
Title: CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation.
Journal: The Journal of biological chemistry 20080905
Title: Long-term efficacy and safety of Chinese made sirolimus eluting stents: results, including off label usage, from two centres over three years.
Journal: Chinese medical journal 20080905
Title: Inhibition of mTOR restores cisplatin sensitivity through down-regulation of growth and anti-apoptotic proteins.
Journal: European journal of pharmacology 20080904
Title: Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer.
Journal: European journal of pharmacology 20080904
Title: Rapamycin reduces VEGF expression in retinal pigment epithelium (RPE) and inhibits RPE-induced sprouting angiogenesis in vitro.
Journal: FEBS letters 20080903
Title: Major treatment improvements encourage kidney cancer researchers to seek further gains.
Journal: Journal of the National Cancer Institute 20080903
Title: SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth.
Journal: Cell metabolism 20080903
Title: Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer.
Journal: The Journal of clinical investigation 20080902
Title: The impact of lesion length and vessel size on outcomes after sirolimus-eluting stent implantation for in-stent restenosis.
Journal: Heart (British Cardiac Society) 20080901
Title: Introducing the first polymer-free leflunomide eluting stent.
Journal: Atherosclerosis 20080901
Title: Combination antifungal therapy involving amphotericin B, rapamycin and 5-fluorocytosine using PEG-phospholipid micelles.
Journal: Pharmaceutical research 20080901
Title: Rapamycin attenuates the severity of established nephritis in lupus-prone NZB/W F1 mice.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080901
Title: Use of sirolimus in IPEX and IPEX-like children.
Journal: Journal of clinical immunology 20080901
Title: Kaposi's sarcoma and mTOR: a crossroad between viral infection neoangiogenesis and immunosuppression.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20080901
Title: The alpha4-containing form of protein phosphatase 2A in liver and hepatic cells.
Journal: Journal of cellular biochemistry 20080901
Title: Rapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-cells.
Journal: Diabetes 20080901
Title: Maternal protein restriction during early lactation induces GLUT4 translocation and mTOR/Akt activation in adipocytes of adult rats.
Journal: American journal of physiology. Endocrinology and metabolism 20080901
Title: Lifetime cost-effectiveness of calcineurin inhibitor withdrawal after de novo renal transplantation.
Journal: Journal of the American Society of Nephrology : JASN 20080901
Title: Late and very late stent thrombosis following drug-eluting stent implantation in unprotected left main coronary artery: a multicentre registry.
Journal: European heart journal 20080901
Title: Autophagy-inducing agents augment the antitumor effect of telerase-selve oncolytic adenovirus OBP-405 on glioblastoma cells.
Journal: Gene therapy 20080901
Title: Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin.
Journal: Molecular and cellular neurosciences 20080901
Title: Huntington's disease: degradation of mutant huntingtin by autophagy.
Journal: The FEBS journal 20080901
Title: A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression.
Journal: American journal of physiology. Cell physiology 20080901
Title: Late drug-eluting stent thrombosis in unprotected left main coronary artery lesions--sometimes possible, but rarely definite or probable.
Journal: European heart journal 20080901
Title: Targeted therapy in renal cell carcinoma.
Journal: Current opinion in urology 20080901
Title: Positive reasons for publishing negative findings.
Journal: The American journal of gastroenterology 20080901
Title: A multicenter, randomized, double-blind trial of everolimus versus azathioprine and placebo to maintain steroid-induced remission in patients with moderate-to-severe active Crohn's disease.
Journal: The American journal of gastroenterology 20080901
Title: Strut fracture: a further concern with drug-eluting stents.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20080901
Title: Small molecule enhancers of autophagy for neurodegenerative diseases.
Journal: Molecular bioSystems 20080901
Title: Everolimus (RAD001) and anti-angiogenic cyclophosphamide show long-term control of gastric cancer growth in vivo.
Journal: Cancer biology & therapy 20080901
Title: Sirolimus-induced aphthous ulcers which disappeared with conversion to everolimus.
Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20080901
Title: Use of sirolimus (rapamycin) to treat refractory Crohn's disease.
Journal: Gut 20080901
Title: Ras-mediated up-regulation of survivin expression in cytokine-dependent murine pro-B lymphocytic cells.
Journal: The Tohoku journal of experimental medicine 20080901
Title: One-year clinical outcomes of dialysis patients after implantation with sirolimus-eluting coronary stents.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20080901
Title: Urothelial carcinoma in kidney transplant recipients: conversion from calcineurin inhibitor to proliferation signal inhibitor?
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20080901
Title: Involvement of insulin in early development of mouse one-cell stage embryos.
Journal: Science in China. Series C, Life sciences 20080901
Title: Pharmacodynamic-guided modified continuous reassessment method-based, dose-finding study of rapamycin in adult patients with solid tumors.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080901
Title: Chemoprevention and treatment of experimental Cowden's disease by mTOR inhibition with rapamycin.
Journal: Cancer research 20080901
Title: Safety of drug-coated stents.
Journal: Expert opinion on drug safety 20080901
Title: Late unilateral pulmonary edema in single lung transplant recipients.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080901
Title: mTOR inhibitors and unilateral edema.
Journal: Revista espanola de cardiologia 20080901
Title: Novel therapeutic options in metastatic renal cancer - review and post ASCO 2007 update.
Journal: Reviews on recent clinical trials 20080901
Title: Symptomatic pulmonary allograft Kaposi's sarcoma in two lung transplant recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080901
Title: Impact of variability of sirolimus trough level on chronic allograft nephropathy.
Journal: Transplantation proceedings 20080901
Title: De novo sirolimus-based regimen in Thai renal transplant recipients.
Journal: Transplantation proceedings 20080901
Title: Sirolimus conversion experience in a single center.
Journal: Transplantation proceedings 20080901
Title: Everolimus with reduced-dose cyclosporine in de novo renal transplant recipients: Philippine experience.
Journal: Transplantation proceedings 20080901
Title: Possible mechanism by which rapamycin increases cyclosporine nephrotoxicity.
Journal: Transplantation proceedings 20080901
Title: Sirolimus does not absolutely abolish the occurrence/recurrence of urothelial carcinoma in renal transplant recipients.
Journal: Transplantation proceedings 20080901
Title: Late spontaneous kidney graft decapsulation after administration of sirolimus in a recipient with chronic hepatitis B and C infection: a case report.
Journal: Transplantation proceedings 20080901
Title: Sirolimus used during pregnancy in a living related renal transplant recipient: a case report.
Journal: Transplantation proceedings 20080901
Title: Long-term efficacy and safety of sirolimus-eluting vs bare-metal stents.
Journal: Connecticut medicine 20080901
Title: [Renal cell carcinoma].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20080901
Title: Pilot study of rapamycin in patients with hormone-refractory prostate cancer.
Journal: Clinical genitourinary cancer 20080901
Title: NCCN Task Force Report: mTOR inhibition in solid tumors.
Journal: Journal of the National Comprehensive Cancer Network : JNCCN 20080901
Title: Clinical investigations in T-cell and NK-cell non-Hodgkin lymphoma.
Journal: Clinical advances in hematology & oncology : H&O 20080901
Title: Use of sirolimus in a case of severe paraquat poisoning.
Journal: Clinical toxicology (Philadelphia, Pa.) 20080901
Title: Complete fracture and restenosis of sirolimus-eluting stent in ostial saphenous vein graft.
Journal: International journal of cardiology 20080829
Title: Drug eluting stents in patients with diabetes.
Journal: BMJ (Clinical research ed.) 20080829
Title: Rapamycin inhibits F-actin reorganization and phosphorylation of focal adhesion proteins.
Journal: Oncogene 20080828
Title: Reduction in erythropoietin resistance after conversion from sirolimus to enteric coated mycophenolate sodium.
Journal: Transplantation 20080827
Title: Improved renal function, with similar proteinuria, after two years of early tacrolimus withdrawal from a regimen of sirolimus plus tacrolimus.
Journal: Transplantation 20080827
Title: A randomized comparison of sirolimus- versus Paclitaxel-eluting stent implantation in patients with diabetes mellitus.
Journal: Journal of the American College of Cardiology 20080826
Title: Angioscopic comparison of neointimal coverage between zotarolimus- and sirolimus-eluting stents.
Journal: Journal of the American College of Cardiology 20080826
Title: Heterogeneous nuclear ribonucleoprotein A1 regulates cyclin D1 and c-myc internal ribosome entry site function through Akt signaling.
Journal: The Journal of biological chemistry 20080822
Title: Firebird and cypher sirolimus-eluting stents and bare metal stents in treatment of very long coronary lesions.
Journal: Chinese medical journal 20080820
Title: Quantitation of autophagy by luciferase release assay.
Journal: Autophagy 20080816
Title: Frequency modulation of synchronized Ca(2+) spikes in cultured hippocampal networks through mTOR.
Journal: Neuroscience letters 20080815
Title: Effect of rapamycin alone and in combination with sorafenib in an orthotopic model of human hepatocellular carcinoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080815
Title: Prolongation of cardiac allograft survival by rapamycin and the invariant natural killer T cell glycolipid agonist OCH.
Journal: Transplantation 20080815
Title: S6K1 plays a key role in glial transformation.
Journal: Cancer research 20080815
Title: Tumorigenic activity and therapeutic inhibition of Rheb GTPase.
Journal: Genes & development 20080815
Title: Watchdog set to reject four drugs for kidney cancer on the NHS.
Journal: BMJ (Clinical research ed.) 20080814
Title: Progression-free survival as endpoint in metastatic RCC?
Journal: Lancet (London, England) 20080809
Title: Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial.
Journal: Lancet (London, England) 20080809
Title: A strategy to offset the extra cost of sirolimus-eluting stent in patients undergoing intervention for acute myocardial infarction.
Journal: International journal of cardiology 20080801
Title: Activation of the mTOR signaling pathway in breast cancer and its correlation with the clinicopathologic variables.
Journal: Breast cancer research and treatment 20080801
Title: Everolimus in patients with rheumatoid arthritis receiving concomitant methotrexate: a 3-month, double-blind, randomised, placebo-controlled, parallel-group, proof-of-concept study.
Journal: Annals of the rheumatic diseases 20080801
Title: Sirolimus and regression of Kaposi's sarcoma in immunosuppressed transplant patient.
Journal: Journal of the European Academy of Dermatology and Venereology : JEADV 20080801
Title: Antineoplastic effect of rapamycin is potentiated by inhibition of IRS-1 signaling in prostate cancer cells xenografts.
Journal: Journal of cancer research and clinical oncology 20080801
Title: Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells.
Journal: The Journal of investigative dermatology 20080801
Title: The PI 3-kinase and mTOR signaling pathways are important modulators of epithelial tubule formation.
Journal: Journal of cellular physiology 20080801
Title: Temsirolimus safety profile and management of toxic effects in patients with advanced renal cell carcinoma and poor prognostic features.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20080801
Title: Hypoxia-inducible factor-2alpha: effect on radiation sensitivity and differential regulation by an mTOR inhibitor.
Journal: BJU international 20080801
Title: The macrolide everolimus forms an unusual metabolite in animals and humans: identification of a phosphocholine ester.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080801
Title: mTOR in squamous cell carcinoma of the oesophagus: a potential target for molecular therapy?
Journal: Journal of clinical pathology 20080801
Title: Differential effects of rapamycin in anti-GBM glomerulonephritis.
Journal: Journal of the American Society of Nephrology : JASN 20080801
Title: Stimulation of autophagy suppresses the intracellular survival of Burkholderia pseudomallei in mammalian cell lines.
Journal: Autophagy 20080801
Title: What controls TOR?
Journal: IUBMB life 20080801
Title: Localization of autophagy-related proteins in yeast using a versatile plasmid-based resource of fluorescent protein fusions.
Journal: Autophagy 20080801
Title: Temsirolimus in metastatic renal cell carcinoma.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20080801
Title: mTOR inhibitor monotherapy is insufficient to suppress viremia and disease progression in Epstein-Barr virus-driven lymphoproliferative disorders (EBV-LPD).
Journal: American journal of hematology 20080801
Title: Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: a phase 2 trial in the North Central Cancer Treatment Group.
Journal: Cancer 20080801
Title: The mTOR inhibitor rapamycin significantly improves facial angiofibroma lesions in a patient with tuberous sclerosis.
Journal: The British journal of dermatology 20080801
Title: Randomized trial of three rapamycin-eluting stents with different coating strategies for the reduction of coronary restenosis.
Journal: European heart journal 20080801
Title: The potential clinical utility of intravascular ultrasound guidance in patients undergoing percutaneous coronary intervention with drug-eluting stents.
Journal: European heart journal 20080801
Title: The effect of rapamycin on DNA synthesis in multiple tissues from late gestation fetal and postnatal rats.
Journal: American journal of physiology. Cell physiology 20080801
Title: Vascular endothelial growth factor protein levels and gene expression in peripheral monocytes after stenting: a randomized comparative study of sirolimus-eluting and bare-metal stents.
Journal: European heart journal 20080801
Title: Patient selection critical for calcineurin inhibitor withdrawal in pediatric kidney transplantation.
Journal: Pediatric transplantation 20080801
Title: Hepatic translation control in the late-gestation fetal rat.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20080801
Title: Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis.
Journal: Nature medicine 20080801
Title: Effect of sirolimus on left ventricular hypertrophy in kidney transplant recipients: a 1-year nonrandomized controlled trial.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20080801
Title: Biodegradable coating for drug-eluting stents--more than a facelift?
Journal: European heart journal 20080801
Title: Combination of rapamycin and 17-allylamino-17-demethoxygeldanamycin abrogates Akt activation and potentiates mTOR blockade in breast cancer cells.
Journal: Anti-cancer drugs 20080801
Title: In-vitro synergism of m-TOR inhibitors, statins, and classical chemotherapy: potential implications in acute leukemia.
Journal: Anti-cancer drugs 20080801
Title: Sirolimus-eluting stent implantation for bare-metal in-stent restenosis: is there any evidence for a late catch-up phenomenon?
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20080801
Title: Clinical-grade preparation of human natural regulatory T-cells encoding the thymidine kinase suicide gene as a safety gene.
Journal: The journal of gene medicine 20080801
Title: The MAP kinase-activated protein kinase Rck2p plays a role in rapamycin sensitivity in Saccharomyces cerevisiae and Candida albicans.
Journal: FEMS yeast research 20080801
Title: Nutrient content of diet affects the signaling activity of the insulin/target of rapamycin/p70 S6 kinase pathway in the African malaria mosquito Anopheles gambiae.
Journal: Journal of insect physiology 20080801
Title: Two-year outcome of patients treated with sirolimus- versus paclitaxel-eluting stents in an unselected population with coronary artery disease (from the REWARDS Registry).
Journal: The American journal of cardiology 20080801
Title: Intravascular ultrasound evaluation of optimal drug-eluting stent expansion after poststent balloon dilation using a noncompliant balloon versus a semicompliant balloon (from the Poststent Optimal Stent Expansion Trial [POET]).
Journal: The American journal of cardiology 20080801
Title: Angiographic patterns of drug-eluting stent restenosis and one-year outcomes after treatment with repeated percutaneous coronary intervention.
Journal: The American journal of cardiology 20080801
Title: Sirolimus, tacrolimus, and low-dose methotrexate as graft-versus-host disease prophylaxis in related and unrelated donor reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080801
Title: Sirolimus in combination with tacrolimus in allogeneic stem cell transplantation--timing and conditioning regimen may be crucial.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080801
Title: Development of a predictive limited sampling strategy for estimation of mycophenolic acid area under the concentration time curve in patients receiving concomitant sirolimus or cyclosporine.
Journal: Therapeutic drug monitoring 20080801
Title: Biodegradable polymers--are they the answer to late stent thrombosis? Too early to tell.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080801
Title: Novel bioabsorbable salicylate-based polymer as a drug-eluting stent coating.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080801
Title: Early days of an ingenious aspirin and sirolimus-eluting stent.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080801
Title: Long-term clinical, angiographic, and intravascular ultrasound outcomes of biodegradable polymer-coated sirolimus-eluting stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080801
Title: Optical coherence tomography: high resolution intravascular imaging to evaluate vascular healing after coronary stenting.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080801
Title: Sirolimus amelioration of clinical symptoms of recurrent lymphangioleiomyomatosis after living-donor lobar lung transplantation.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080801
Title: Evaluation of a deuterium-labeled internal standard for the measurement of sirolimus by high-throughput HPLC electrospray ionization tandem mass spectrometry.
Journal: Clinical chemistry 20080801
Title: Corneal permeation studies of everolimus microemulsion.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20080801
Title: A small molecule-directed approach to control protein localization and function.
Journal: Yeast (Chichester, England) 20080801
Title: Evaluation of the mammalian target of rapamycin pathway and the effect of rapamycin on target expression and cellular proliferation in osteosarcoma cells from dogs.
Journal: American journal of veterinary research 20080801
Title: Temsirolimus, an mTOR inhibitor for treatment of patients with advanced renal cell carcinoma.
Journal: Clinical journal of oncology nursing 20080801
Title: Two-year intravascular ultrasound observations in diabetic patients treated with single and double dose sirolimus-eluting stents: results of the double dose diabetes (3D) study.
Journal: The Journal of invasive cardiology 20080801
Title: Coexistent in-stent restenosis, late incomplete stent apposition and mural thrombus in a zotarolimus-eluting stent.
Journal: The Journal of invasive cardiology 20080801
Title: 'Black hole' restenosis after sirolimus-eluting stent implantation.
Journal: The Journal of invasive cardiology 20080801
Title: Oral sirolimus for prevention of recurrent infrainguinal arterial obstructions after surgical and endovascular revascularizations.
Journal: VASA. Zeitschrift fur Gefasskrankheiten 20080801
Title: Rapamycin modulates the maturation of rat bone marrow-derived dendritic cells.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20080801
Title: [Can defective TGF-Beta signaling be an Achilles heel in human cancer?].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20080801
Title: In-stent restenosis in bare metal stents versus sirolimus-eluting stents after primary coronary intervention for acute myocardial infarction and subsequent transcoronary transplantation of autologous stem cells.
Journal: Clinical cardiology 20080801
Title: Aging, stem cells, and mammalian target of rapamycin: a prospect of pharmacologic rejuvenation of aging stem cells.
Journal: Rejuvenation research 20080801
Title: Cotylenin A, a new differentiation inducer, and rapamycin cooperatively inhibit growth of cancer cells through induction of cyclin G2.
Journal: Cancer science 20080801
Title: Inference of protein complex activities from chemical-genetic profile and its applications: predicting drug-target pathways.
Journal: PLoS computational biology 20080801
Title: What the similarities of specific polycystic liver and kidney diseases can teach us about both.
Journal: Nephrology news & issues 20080801
Title: Conversion from sirolimus to everolimus in maintenance renal transplant recipients within a calcineurin inhibitor-free regimen: results of a 6-month pilot study.
Journal: Clinical nephrology 20080801
Title: [Effect of rapamycin in inducing naïve murine effector T cell convert to regulatory T cell].
Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20080801
Title: [Rapamycin-loaded poly (lactic-co-glycolic) acid nanoparticles for intraarterial local drug delivery: preparation, characterization, and in vitro/in vivo release].
Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20080801
Title: Clinical outcomes of sirolimus with eluting stent implantation in coronary artery disease.
Journal: JPMA. The Journal of the Pakistan Medical Association 20080801
Title: One year results of a new in situ length-adjustable stent platform with a biodegradable biolimus A9 eluting polymer: results of the CUSTOM-II trial.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080801
Title: Safety in simple versus complex stenting of coronary artery bifurcation lesions. The nordic bifurcation study 14-month follow-up results.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080801
Title: Elective implantation of sirolimus-eluting stents for bifurcated and non-bifurcated unprotected left main coronary artery lesions: clinical outcomes at one year.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080801
Title: 3-year follow-up of the SISR (Sirolimus-Eluting Stents Versus Vascular Brachytherapy for In-Stent Restenosis) trial.
Journal: JACC. Cardiovascular interventions 20080801
Title: Lack of association between large angiographic late loss and low risk of in-stent thrombus: angioscopic comparison between paclitaxel- and sirolimus-eluting stents.
Journal: Circulation. Cardiovascular interventions 20080801
Title: Antidepressive-like effects of rapamycin in animal models: Implications for mTOR inhibition as a new target for treatment of affective disorders.
Journal: Brain research bulletin 20080730
Title: Endothelial cell recovery between comparator polymer-based drug-eluting stents.
Journal: Journal of the American College of Cardiology 20080729
Title: Beneficial effect of omega-3 fatty acids on sirolimus- or everolimus-induced hypertriglyceridemia in heart transplant recipients.
Journal: Transplantation 20080727
Title: Clinical trials probe new therapies for some difficult-to-treat cancers.
Journal: JAMA 20080723
Title: Anti-proinflammatory effects of sirolimus on human islet preparations.
Journal: Transplantation 20080715
Title: Chronic kidney disease--a common and serious complication after intestinal transplantation.
Journal: Transplantation 20080715
Title: Prolongation of cardiac and islet allograft survival by a blocking hamster anti-mouse CXCR3 monoclonal antibody.
Journal: Transplantation 20080715
Title: Sirolimus (rapamycin) induced proteinuria in a patient undergoing allogeneic hematopoietic stem cell transplant.
Journal: Transplantation 20080715
Title: Sirolimus in metatastic renal cell carcinoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080710
Title: [Effects of sirolimus-eluting stent and the paclitaxel-eluting stent: a three-year follow-up study].
Journal: Zhonghua yi xue za zhi 20080708
Title: Simultaneous subacute stent thrombosis after implantation of sirolimus-eluting stent and bare-metal stent.
Journal: International journal of cardiology 20080704
Title: Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors.
Journal: Oncogene 20080703
Title: Localization of polypyrimidine-tract-binding protein is involved in the regulation of albumin synthesis by branched-chain amino acids in HepG2 cells.
Journal: The Journal of nutritional biochemistry 20080701
Title: Antiproliferative effects of rapamycin as a single agent and in combination with carboplatin and paclitaxel in head and neck cancer cell lines.
Journal: Cancer chemotherapy and pharmacology 20080701
Title: Sirolimus enhances the effect of apoptotic cell infusion on hematopoietic engraftment and tolerance induction.
Journal: Leukemia 20080701
Title: Incisional surgical site infection in kidney transplantation.
Journal: Urology 20080701
Title: Systemic inhibition of mammalian target of rapamycin inhibits fear memory reconsolidation.
Journal: Neurobiology of learning and memory 20080701
Title: Treatment of in-stent restenosis with sirolimus-eluting-stents: results from the prospective German Cypher stent registry.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20080701
Title: Introduction: new insights, treatments, and management strategies for ADPKD.
Journal: Clinical journal of the American Society of Nephrology : CJASN 20080701
Title: Sirolimus is associated with new-onset diabetes in kidney transplant recipients.
Journal: Journal of the American Society of Nephrology : JASN 20080701
Title: Prospective randomized comparison of sirolimus- versus paclitaxel-eluting stents for the treatment of acute ST-elevation myocardial infarction: pROSIT trial.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080701
Title: Fluvastatin synergistically improves the antiproliferative effect of everolimus on rat smooth muscle cells by altering p27Kip1/cyclin E expression.
Journal: Molecular pharmacology 20080701
Title: Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer.
Journal: Autophagy 20080701
Title: Caveolin-1 increases basal and TGF-beta1-induced expression of type I procollagen through PI-3 kinase/Akt/mTOR pathway in human dermal fibroblasts.
Journal: Cellular signalling 20080701
Title: Leucine induces phosphorylation and activation of p70S6K in cortical neurons via the system L amino acid transporter.
Journal: Journal of neurochemistry 20080701
Title: Rapamycin affects early fracture healing in mice.
Journal: British journal of pharmacology 20080701
Title: Phase I, pharmacokinetic and pharmacodynamic study of the anti-insulinlike growth factor type 1 Receptor monoclonal antibody CP-751,871 in patients with multiple myeloma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080701
Title: Inhibition of mTOR in combination with doxorubicin in an experimental model of hepatocellular carcinoma.
Journal: Journal of hepatology 20080701
Title: Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma.
Journal: Journal of hepatology 20080701
Title: Glibenclamide activates translation in rat pancreatic beta cells through calcium-dependent mTOR, PKA and MEK signalling pathways.
Journal: Diabetologia 20080701
Title: Multivariate analysis applied to the study of spatial distributions found in drug-eluting stent coatings by confocal Raman microscopy.
Journal: Analytical chemistry 20080701
Title: Mammalian target of rapamycin inhibitor dyslipidemia in kidney transplant recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080701
Title: Sirolimus may reduce fertility in male renal transplant recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080701
Title: Caffeine extends yeast lifespan by targeting TORC1.
Journal: Molecular microbiology 20080701
Title: Evaluation of the variables characterized by significant discriminating power in the application of SIMCA classification method to proteomic studies.
Journal: Journal of proteome research 20080701
Title: Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model.
Journal: The Journal of clinical investigation 20080701
Title: Sirolimus-associated pneumonitis in heart transplant recipients.
Journal: The Annals of pharmacotherapy 20080701
Title: Drug-eluting stents in ST elevation myocardial infarction: In light of the PROSIT trial.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080701
Title: IL-1beta-driven ST2L expression promotes maturation resistance in rapamycin-conditioned dendritic cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20080701
Title: Intravascular ultrasound assessment of expansion of the sirolimus-eluting (cypher select) and paclitaxel-eluting (Taxus Express-2) stent in patients with diabetes mellitus.
Journal: The American journal of cardiology 20080701
Title: Comparison of neointimal coverage by optical coherence tomography of a sirolimus-eluting stent versus a bare-metal stent three months after implantation.
Journal: The American journal of cardiology 20080701
Title: Safety and efficacy of sirolimus-eluting stent in patients with acute coronary syndrome undergoing emergency procedure.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20080701
Title: Very late stent thrombosis associated with multiple stent fractures and peri-stent aneurysm formation after sirolimus-eluting stent implantation.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20080701
Title: Diabetes after transplantation and sirolimus: what's the connection?
Journal: Journal of the American Society of Nephrology : JASN 20080701
Title: De-novo [corrected] post renal transplantation inflammatory bowel disease.
Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20080701
Title: New drugs08, part 2.
Journal: Nursing 20080701
Title: Everolimus-related pulmonary toxicity in heart transplant recipients.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080701
Title: Renal cell carcinoma: the translation of molecular biology into new treatments, new patient outcomes, and nursing implications.
Journal: Oncology nursing forum 20080701
Title: Corticosteroid interactions with cyclosporine, tacrolimus, mycophenolate, and sirolimus: fact or fiction?
Journal: The Annals of pharmacotherapy 20080701
Title: [Targeted therapy for locally advanced and/or metastatic bladder cancer].
Journal: Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20080701
Title: Genetic interactions of MAF1 identify a role for Med20 in transcriptional repression of ribosomal protein genes.
Journal: PLoS genetics 20080701
Title: Angiographic time course of in-stent restenosis with zotarolimus drug-eluting stents.
Journal: The Canadian journal of cardiology 20080701
Title: Formation of tissue factor-factor VIIa-factor Xa complex induces activation of the mTOR pathway which regulates migration of human breast cancer cells.
Journal: Thrombosis and haemostasis 20080701
Title: Variability in the prevalence of acute bronchoresponsiveness in different populations of patients with lymphangioleiomyomatosis.
Journal: Chest 20080701
Title: Favorable results of concomitant tacrolimus and sirolimus therapy in Taiwanese renal transplant recipients at 12 months.
Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20080701
Title: [Effeet of rapamycin on mTOR and eIF-4E expression in coxsackievirus B3-induced rat myocardial cells].
Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20080701
Title: Drug eluting stents: friend or foe? A review of cellular mechanisms behind the effects of Paclitaxel and sirolimus eluting stents.
Journal: Current drug metabolism 20080701
Title: Oral everolimus inhibits neointimal proliferation in prosthetic pulmonary valved stents in pigs.
Journal: The Journal of heart valve disease 20080701
Title: [Comparison of different drug-eluting stents in the treatment of coronary artery disease: a single center four-year clinical follow-up].
Journal: Zhonghua nei ke za zhi 20080701
Title: Comparison of vascular response after sirolimus-eluting stent implantation between patients with unstable and stable angina pectoris: a serial optical coherence tomography study.
Journal: JACC. Cardiovascular imaging 20080701
Title: Does underlying plaque morphology play a role in vessel healing after drug-eluting stent implantation?
Journal: JACC. Cardiovascular imaging 20080701
Title: Cyclosporine A and Rapamycin induce in vitro cholesteryl ester transfer protein activity, and suppress lipoprotein lipase activity in human plasma.
Journal: International journal of pharmaceutics 20080624
Title: Clinical efficacy of drug-eluting stents in diabetic patients: a meta-analysis.
Journal: Journal of the American College of Cardiology 20080624
Title: Novel genetically encoded biosensors using firefly luciferase.
Journal: ACS chemical biology 20080620
Title: Delivery of rapamycin-loaded nanoparticle down regulates ICAM-1 expression and maintains an immunosuppressive profile in human CD34+ progenitor-derived dendritic cells.
Journal: Journal of biomedical materials research. Part A 20080615
Title: Development of a novel biocompatible polymer system for extended drug release in a next-generation drug-eluting stent.
Journal: Journal of biomedical materials research. Part A 20080615
Title: Impact of stent deployment procedural factors on long-term effectiveness and safety of sirolimus-eluting stents (final results of the multicenter prospective STLLR trial).
Journal: The American journal of cardiology 20080615
Title: Protein phosphatase 2A and rapamycin regulate the nuclear localization and activity of the transcription factor GLI3.
Journal: Cancer research 20080615
Title: PTEN loss does not predict for response to RAD001 (Everolimus) in a glioblastoma orthotopic xenograft test panel.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080615
Title: The forgotten player of in-stent restenosis: endothelial dysfunction.
Journal: International journal of cardiology 20080606
Title: Reduced exposure to calcineurin inhibitors in renal transplantation.
Journal: The New England journal of medicine 20080605
Title: Differential effects of ketoconazole on exposure to temsirolimus following intravenous infusion of temsirolimus.
Journal: British journal of cancer 20080603
Title: Differential effects of drug-eluting stents on local endothelium-dependent coronary vasomotion.
Journal: Journal of the American College of Cardiology 20080603
Title: Sirolimus-induced vascular dysfunction. Increased mitochondrial and nicotinamide adenosine dinucleotide phosphate oxidase-dependent superoxide production and decreased vascular nitric oxide formation.
Journal: Journal of the American College of Cardiology 20080603
Title: Endothelial dysfunction associated with drug-eluting stents what, where, when, and how?
Journal: Journal of the American College of Cardiology 20080603
Title: Contribution of organized thrombus to in-stent restenosis after sirolimus-eluting stent implantation: optical coherence tomography findings.
Journal: European heart journal 20080601
Title: Sirolimus and intraoperative hyperthermic peritoneal chemoperfusion with mitomycin-C do not impair healing of bowel anastomoses.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20080601
Title: In human endothelial cells rapamycin causes mTORC2 inhibition and impairs cell viability and function.
Journal: Cardiovascular research 20080601
Title: Immunosuppressive medications, clinical and metabolic parameters in new-onset diabetes mellitus after kidney transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20080601
Title: Everolimus for refractory Crohn's disease: a case report.
Journal: Inflammatory bowel diseases 20080601
Title: Inhibition of mTOR by sirolimus induces remission of post-transplant lymphoproliferative disorders.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20080601
Title: Combination of rapamycin and IL-2 increases de novo induction of human CD4(+)CD25(+)FOXP3(+) T cells.
Journal: Journal of autoimmunity 20080601
Title: Response of human renal tubular cells to cyclosporine and sirolimus: a toxicogenomic study.
Journal: Toxicology and applied pharmacology 20080601
Title: Long-term efficacy and safety of a calcineurin inhibitor-free regimen in live-donor renal transplant recipients.
Journal: Journal of the American Society of Nephrology : JASN 20080601
Title: Effect of Paclitaxel-eluting versus sirolimus-eluting stents on coronary restenosis in Korean diabetic patients.
Journal: Journal of interventional cardiology 20080601
Title: Graft rejection: pharmacogenetic analysis or drug anamnesis?
Journal: British journal of clinical pharmacology 20080601
Title: Simultaneous quantification of cyclosporine, tacrolimus, sirolimus and everolimus in whole blood by liquid chromatography-electrospray mass spectrometry.
Journal: Clinical biochemistry 20080601
Title: RAD001 (Everolimus) inhibits growth of prostate cancer in the bone and the inhibitory effects are increased by combination with docetaxel and zoledronic acid.
Journal: The Prostate 20080601
Title: Lithium-mediated suppression of morphogenesis and growth in Candida albicans.
Journal: FEMS yeast research 20080601
Title: Difficult stent delivery: use of an aspiration catheter as a 'sheath'.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080601
Title: Comparison of Akt/mTOR signaling in primary breast tumors and matched distant metastases.
Journal: Cancer 20080601
Title: Long-term clinical outcomes of real-world experience using sirolimus-eluting stents in saphenous vein graft disease.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080601
Title: Safety of drug-eluting stents.
Journal: Nature clinical practice. Cardiovascular medicine 20080601
Title: Rapamycin conditionally inhibits Hsp90 but not Hsp70 mRNA translation in Drosophila: implications for the mechanisms of Hsp mRNA translation.
Journal: Cell stress & chaperones 20080601
Title: Regulated insulin delivery from human epidermal cells reverses hyperglycemia.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20080601
Title: Rapamycin treatment for a child with germline PTEN mutation.
Journal: Nature clinical practice. Oncology 20080601
Title: Pharmacodynamic effects of everolimus on anti-CD3 antibody-stimulated T-lymphocyte proliferation and interleukin-10 synthesis in stable kidney-transplant patients.
Journal: Cytokine 20080601
Title: Expression of c-Kit isoforms in multiple myeloma: differences in signaling and drug sensitivity.
Journal: Haematologica 20080601
Title: An Epstein-Barr virus positive natural killer lymphoma xenograft derived for drug testing.
Journal: Leukemia & lymphoma 20080601
Title: Autophagy activation by rapamycin eliminates mouse Mallory-Denk bodies and blocks their proteasome inhibitor-mediated formation.
Journal: Hepatology (Baltimore, Md.) 20080601
Title: Multicenter trial of everolimus in pediatric renal transplant recipients: results at three year.
Journal: Pediatric transplantation 20080601
Title: Study comparing the double kissing (DK) crush with classical crush for the treatment of coronary bifurcation lesions: the DKCRUSH-1 Bifurcation Study with drug-eluting stents.
Journal: European journal of clinical investigation 20080601
Title: Impact of body mass index on the one-year clinical outcome of patients undergoing multivessel revascularization with sirolimus-eluting stents (from the Arterial Revascularization Therapies Study Part II).
Journal: The American journal of cardiology 20080601
Title: Comparison of effectiveness and safety of sirolimus-eluting stents versus bare-metal stents in patients with diabetes mellitus (from the Italian Multicenter Randomized DESSERT Study).
Journal: The American journal of cardiology 20080601
Title: Differential involvement of IkappaB kinases alpha and beta in cytokine- and insulin-induced mammalian target of rapamycin activation determined by Akt.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20080601
Title: Drug reactions - new observations.
Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20080601
Title: Drug-eluting stent in saphenous vein graft lesions.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080601
Title: Platelet glycoprotein IIb/IIIa receptor inhibitors: is their future as bright as their past?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080601
Title: Impact of platelet glycoprotein IIb/IIIa receptor inhibitors on outcomes of diabetic patients undergoing percutaneous coronary interventions using sirolimus-eluting stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080601
Title: Angiographic and clinical outcomes after sirolimus-eluting stent implantation to de novo ostial lesion of the right coronary artery: a retrospective study.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20080601
Title: Sirolimus-eluting stents suppress neointimal formation irrespective of metallic allergy.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20080601
Title: Concurrent administration of sirolimus and voriconazole: a pilot study assessing safety and approaches to appropriate management.
Journal: Pharmacotherapy 20080601
Title: Preliminary study of the use of drug-eluting stents in atherosclerotic renal artery stenoses 4 mm in diameter or smaller.
Journal: Journal of vascular and interventional radiology : JVIR 20080601
Title: Safety and efficacy of overlapping sirolimus-eluting versus paclitaxel-eluting stents.
Journal: American heart journal 20080601
Title: Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK.
Journal: Genes & development 20080601
Title: Human melanoma cytolysis by combined inhibition of mammalian target of rapamycin and vascular endothelial growth factor/vascular endothelial growth factor receptor-2.
Journal: Cancer research 20080601
Title: Changes in tumor metabolism as readout for Mammalian target of rapamycin kinase inhibition by rapamycin in glioblastoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080601
Title: Combination strategy targeting the hypoxia inducible factor-1 alpha with mammalian target of rapamycin and histone deacetylase inhibitors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080601
Title: Very late sirolimus-eluting stent displaced fracture in the mid-left anterior descending artery.
Journal: The Journal of invasive cardiology 20080601
Title: Midterm results of a sirolimus-eluting stent implanted for recurrent carotid in-stent restenosis.
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20080601
Title: A novel bioengineered small-caliber vascular graft incorporating heparin and sirolimus: excellent 6-month patency.
Journal: The Journal of thoracic and cardiovascular surgery 20080601
Title: Failure of immunosuppressive drug levels to predict T-cell reactivity in pediatric transplant patients.
Journal: Journal of pediatric surgery 20080601
Title: Mammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignancies.
Journal: Molecular cancer therapeutics 20080601
Title: Intrinsically lower AKT, mammalian target of rapamycin, and hypoxia-inducible factor activity correlates with increased sensitivity to 2-deoxy-D-glucose under hypoxia in lung cancer cell lines.
Journal: Molecular cancer therapeutics 20080601
Title: Reduced risk of cytomegalovirus infection in solid organ transplant recipients treated with sirolimus: a pooled analysis of clinical trials.
Journal: Transplantation proceedings 20080601
Title: Observation of efficacy and safety of converting the calcineurin inhibitor to sirolimus in renal transplant recipients with chronic allograft nephropathy.
Journal: Transplantation proceedings 20080601
Title: The impact of conversion from mycophenolate mofetil to mycophenolate sodium among renal transplant recipients on a sirolimus-based regimen.
Journal: Transplantation proceedings 20080601
Title: Sirolimus-based immunosuppressive therapy in liver transplant recipient with tacrolimus-related chronic renal insufficiency.
Journal: Transplantation proceedings 20080601
Title: Demyelinating sensorimotor polyneuropathy associated with the use of sirolimus: a case report.
Journal: Transplantation proceedings 20080601
Title: Rapamycin, mycophenolate mofetil, methylprednisolone, and cytotoxic T-lymphocyte-associated antigen 4 immunoglobulin-based conditioning regimen to induce partial tolerance to hind limb allografts without cytoreductive conditioning.
Journal: Transplantation proceedings 20080601
Title: Antiproliferative and overadditive effects of rapamycin and FTY720 in pancreatic cancer cells in vitro.
Journal: Transplantation proceedings 20080601
Title: Case report: successful treatment of posttransplant lymphoproliferative disorder and quiescence of dermatomyositis with rituximab and sirolimus.
Journal: Transplantation proceedings 20080601
Title: Chylous ascites in a renal transplant recipient under sirolimus (rapamycin) treatment.
Journal: Transplantation proceedings 20080601
Title: Everolimus: an update on the mechanism of action, pharmacokinetics and recent clinical trials.
Journal: Expert opinion on drug metabolism & toxicology 20080601
Title: Short-term Efficacy of Topical Immunosuppressive Agents on the Survival of Cultivated Allo-Conjunctival Equivalents.
Journal: Korean journal of ophthalmology : KJO 20080601
Title: A retrospective study of conversion from tacrolimus-based to sirolimus-based immunosuppression in orthotopic liver transplant recipients.
Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20080601
Title: [Recent progress in the study on antitumor drugs targeting hypoxia-inducible factor-1].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080601
Title: [Side branch occlusion rate at sites of overlapping sirolimus- or paclitaxel-eluting stents for treating long coronary lesions].
Journal: Zhonghua xin xue guan bing za zhi 20080601
Title: Abnormal vasomotor function of porcine coronary arteries distal to sirolimus-eluting stents.
Journal: JACC. Cardiovascular interventions 20080601
Title: AMP-activated protein kinase is essential for survival in chronic hypoxia.
Journal: Biochemical and biophysical research communications 20080530
Title: Randomized trial of single-dose versus divided-dose rabbit anti-thymocyte globulin induction in renal transplantation: an interim report.
Journal: Transplantation 20080527
Title: Long-term outcome in patients treated with sirolimus-eluting stents in complex coronary artery lesions: 3-year results of the SCANDSTENT (Stenting Coronary Arteries in Non-Stress/Benestent Disease) trial.
Journal: Journal of the American College of Cardiology 20080527
Title: Aminoacyl-tRNA synthetase inhibitors as potent and synergistic immunosuppressants.
Journal: Journal of medicinal chemistry 20080522
Title: DTCA for PTCA--crossing the line in consumer health education?
Journal: The New England journal of medicine 20080522
Title: Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080521
Title: Mammalian target of rapamycin contributes to the acquired apoptotic resistance of human mesothelioma multicellular spheroids.
Journal: The Journal of biological chemistry 20080509
Title: Synthesis and drug release properties of poly(ethylene oxide) segmented polysulfone copolymers.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20080508
Title: [Drug-eluting stent-associated thrombosis: clinical relevance of impaired vessel-wall healing].
Journal: Postepy higieny i medycyny doswiadczalnej (Online) 20080508
Title: Study power in the SORT OUT II trial.
Journal: JAMA 20080507
Title: Epstein Barr virus induced lymphoma in a child with IPEX syndrome.
Journal: Pediatric blood & cancer 20080501
Title: Low dose rapamycin does not modulate p-glycoprotein function in acute myeloid leukaemia.
Journal: Leukemia research 20080501
Title: Neointimal coverage of bare-metal and sirolimus-eluting stents evaluated with optical coherence tomography.
Journal: Heart (British Cardiac Society) 20080501
Title: Prevention of atherosclerosis by the mTOR inhibitor everolimus in LDLR-/- mice despite severe hypercholesterolemia.
Journal: Atherosclerosis 20080501
Title: Selective inhibition of SCLC growth by the A12 anti-IGF-1R monoclonal antibody correlates with inhibition of Akt.
Journal: Lung cancer (Amsterdam, Netherlands) 20080501
Title: Inhibitors of mammalian target of rapamycin downregulate MYCN protein expression and inhibit neuroblastoma growth in vitro and in vivo.
Journal: Oncogene 20080501
Title: Insulin-like growth factor-1 (IGF-1) and leucine activate pig myogenic satellite cells through mammalian target of rapamycin (mTOR) pathway.
Journal: Molecular reproduction and development 20080501
Title: Toxicities associated with the administration of sorafenib, sunitinib, and temsirolimus and their management in patients with metastatic renal cell carcinoma.
Journal: European urology 20080501
Title: Effects of stem cell therapy with G-CSF on coronary artery after drug-eluting stent implantation in patients with acute myocardial infarction.
Journal: Heart (British Cardiac Society) 20080501
Title: Accuracy and variability of equations to estimate glomerular filtration rates in renal transplant patients receiving sirolimus and/or calcineurin inhibitor immunosuppression.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20080501
Title: Nitric oxide mediates NMDA-induced persistent inhibition of protein synthesis through dephosphorylation of eukaryotic initiation factor 4E-binding protein 1 and eukaryotic initiation factor 4G proteolysis.
Journal: The Biochemical journal 20080501
Title: Autophagy plays a protective role during zVAD-induced necrotic cell death.
Journal: Autophagy 20080501
Title: Combined treatment with triptolide and rapamycin prolongs graft survival in a mouse model of cardiac transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20080501
Title: Induction of transplantation tolerance by combining non-myeloablative conditioning with delivery of alloantigen by T cells.
Journal: Clinical immunology (Orlando, Fla.) 20080501
Title: Intramural delivery of rapamycin with alphavbeta3-targeted paramagnetic nanoparticles inhibits stenosis after balloon injury.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20080501
Title: Sirolimus-based immunosuppression following liver transplantation for hepatocellular carcinoma.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20080501
Title: Rapamycin suppresses TLR4-triggered IL-6 and PGE(2) production of colon cancer cells by inhibiting TLR4 expression and NF-kappaB activation.
Journal: Molecular immunology 20080501
Title: Renal cell carcinoma.
Journal: Current opinion in oncology 20080501
Title: Novel targets for Huntington's disease in an mTOR-independent autophagy pathway.
Journal: Nature chemical biology 20080501
Title: Impact of rapamycin on liver regeneration.
Journal: Virchows Archiv : an international journal of pathology 20080501
Title: Leucine-enriched nutrients and the regulation of mammalian target of rapamycin signalling and human skeletal muscle protein synthesis.
Journal: Current opinion in clinical nutrition and metabolic care 20080501
Title: Sirolimus in combination with cyclosporine or tacrolimus plus methotrexate for prevention of graft-versus-host disease following hematopoietic cell transplantation from unrelated donors.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080501
Title: Incidence of PTLD in pediatric renal transplant recipients receiving basiliximab, calcineurin inhibitor, sirolimus and steroids.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080501
Title: Amelioration of protein misfolding disease by rapamycin: translation or autophagy?
Journal: Autophagy 20080501
Title: Nanomedicine captures cardiovascular disease.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20080501
Title: Cutting edge: Foxp3-mediated induction of pim 2 allows human T regulatory cells to preferentially expand in rapamycin.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20080501
Title: Constitutive activation of p70 S6 kinase is associated with intrinsic resistance to cisplatin.
Journal: International journal of oncology 20080501
Title: Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells.
Journal: The Journal of clinical investigation 20080501
Title: Sirolimus conversion for renal preservation in liver transplantation: not so fast.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20080501
Title: Sirolimus in liver transplant recipients with renal dysfunction offers no advantage over low-dose calcineurin inhibitor regimens.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20080501
Title: Overproduction of non-translatable mRNA silences. The transcription of Ty1 retrotransposons in S. cerevisiae via functional inactivation of the nuclear cap-binding complex and subsequent hyperstimulation of the TORC1 pathway.
Journal: Yeast (Chichester, England) 20080501
Title: Outcomes after sirolimus- and paclitaxel-eluting stent implantation in patients with insulin-treated diabetes mellitus.
Journal: The American journal of cardiology 20080501
Title: Effect of rapamycin therapy on coronary artery physiology early after cardiac transplantation.
Journal: American heart journal 20080501
Title: Sirolimus for lymphangioleiomyomatosis lesions.
Journal: The New England journal of medicine 20080501
Title: Loss of tuberous sclerosis complex-2 function and activation of mammalian target of rapamycin signaling in endometrial carcinoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080501
Title: A phase 2 clinical trial of deforolimus (AP23573, MK-8669), a novel mammalian target of rapamycin inhibitor, in patients with relapsed or refractory hematologic malignancies.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080501
Title: Coronary aneurysm formation in a patient early after everolimus-eluting stent implantation.
Journal: The Journal of invasive cardiology 20080501
Title: [Coronary artery bypass grafting for simultaneous subacute stent thrombosis after sirolimus-eluting stent implantation].
Journal: Kyobu geka. The Japanese journal of thoracic surgery 20080501
Title: Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors.
Journal: Molecular cancer therapeutics 20080501
Title: Kaposi's sarcoma resolves after sirolimus therapy in a patient with pemphigus vulgaris.
Journal: Archives of dermatology 20080501
Title: Classic Mediterranean Kaposi's sarcoma regression with sirolimus treatment.
Journal: Archives of dermatology 20080501
Title: Molecular target therapies in endometrial cancer: from the basic research to the clinic.
Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20080501
Title: Polycystic kidney disease: will it become treatable?
Journal: Polskie Archiwum Medycyny Wewnetrznej 20080501
Title: [Use of Sirolimus in five pediatric patients undergoing solid organ transplantation].
Journal: Revista medica de Chile 20080501
Title: EXCELLA First-in-Man (FIM) study: safety and efficacy of novolimus-eluting stent in de novo coronary lesions.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080501
Title: Biodegradable-polymer-based, sirolimus-eluting Supralimus stent: 6-month angiographic and 30-month clinical follow-up results from the series I prospective study.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080501
Title: Novel drug eluting stent system for customised treatment of coronary lesions: CUSTOM I feasibility trial 24 month results.
Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080501
Title: Kidney transplant histology after one year of continuous therapy with sirolimus compared with tacrolimus.
Journal: Transplantation 20080427
Title: The incidence and clinical impact of stent strut fractures developed after drug-eluting stent implantation.
Journal: International journal of cardiology 20080425
Title: Safety and efficacy of the CYPHER Select Sirolimus-eluting stent in the 'Real World'--clinical and angiographic results from the China CYPHER Select registry.
Journal: International journal of cardiology 20080425
Title: Comparison of an everolimus-eluting stent and a paclitaxel-eluting stent in patients with coronary artery disease: a randomized trial.
Journal: JAMA 20080423
Title: Next-generation drug-eluting stents: a spirited step forward or more of the same.
Journal: JAMA 20080423
Title: Four-year clinical follow-up of the rapamycin-eluting stent evaluated at Rotterdam Cardiology Hospital registry.
Journal: The American journal of cardiology 20080415
Title: Carcinoma 'en Cuirasse' from cutaneous squamous cell carcinoma in a renal transplant patient.
Journal: Transplantation 20080415
Title: Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma.
Journal: Cancer research 20080415
Title: A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis.
Journal: Cancer research 20080415
Title: Tor pathway control of the nitrogen-responsive DAL5 gene bifurcates at the level of Gln3 and Gat1 regulation in Saccharomyces cerevisiae.
Journal: The Journal of biological chemistry 20080404
Title: The PtdIns(4,5)P2 ligand itself influences the localization of PKCalpha in the plasma membrane of intact living cells.
Journal: Journal of molecular biology 20080404
Title: Initial testing (stage 1) of the mTOR inhibitor rapamycin by the pediatric preclinical testing program.
Journal: Pediatric blood & cancer 20080401
Title: Quantitative spatial distribution of sirolimus and polymers in drug-eluting stents using confocal Raman microscopy.
Journal: Journal of biomedical materials research. Part A 20080401
Title: mTOR is activated in the majority of malignant melanomas.
Journal: The Journal of investigative dermatology 20080401
Title: Drug-eluting stents in renal artery stenosis.
Journal: European radiology 20080401
Title: GLN3 encodes a global regulator of nitrogen metabolism and virulence of C. albicans.
Journal: Fungal genetics and biology : FG & B 20080401
Title: Assessment of potential relationship between wall shear stress and arterial wall response after bare metal stent and sirolimus-eluting stent implantation in patients with diabetes mellitus.
Journal: The international journal of cardiovascular imaging 20080401
Title: [Renal cell carcinoma and antiangiogenic therapies].
Journal: Presse medicale (Paris, France : 1983) 20080401
Title: Evaluation of the dedicated Frontier coronary bifurcation stent: A matched pair analysis with drug-eluting and bare metal stents.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20080401
Title: Sirolimus-eluting stents in the treatment of chronic total coronary occlusions: results from the prospective multi-center German Cypher Stent Registry.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20080401
Title: Rapamycin modulates the eNOS vs. shear stress relationship.
Journal: Cardiovascular research 20080401
Title: mTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes.
Journal: Diabetes 20080401
Title: The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes.
Journal: Traffic (Copenhagen, Denmark) 20080401
Title: Modulation of Na+-Ca2+ exchanger expression by immunosuppressive drugs is isoform-specific.
Journal: Molecular pharmacology 20080401
Title: Rapamycin inhibits polyglutamine aggregation independently of autophagy by reducing protein synthesis.
Journal: Molecular pharmacology 20080401
Title: Roles of autophagy and mTOR signaling in neuronal differentiation of mouse neuroblastoma cells.
Journal: Cellular signalling 20080401
Title: Hypoxia stimulus: An adaptive immune response during dendritic cell maturation.
Journal: Kidney international 20080401
Title: Strategies to induce marked prolongation of secondary skin allograft survival in alloantigen-primed mice.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080401
Title: Development of proteinuria after switch to sirolimus-based immunosuppression in long-term cardiac transplant patients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080401
Title: CD4+ CD25+ FOXP3+ regulatory T cells increase de novo in kidney transplant patients after immunodepletion with Campath-1H.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080401
Title: Long-term effects of rapamycin treatment on insulin mediated phosphorylation of Akt/PKB and glycogen synthase activity.
Journal: Experimental cell research 20080401
Title: Trends in adult post-kidney transplant immunosuppressive use in Australia, 1991-2005.
Journal: Nephrology (Carlton, Vic.) 20080401
Title: Long-term clinical outcomes after sirolimus-eluting stent implantation for treatment of restenosis within bare-metal versus drug-eluting stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401
Title: Identifying optimal biologic doses of everolimus (RAD001) in patients with cancer based on the modeling of preclinical and clinical pharmacokinetic and pharmacodynamic data.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080401
Title: Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: a phase I tumor pharmacodynamic study in patients with advanced solid tumors.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080401
Title: Phase I pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080401
Title: Evaluation and management of steroid-unresponsive nephrotic syndrome.
Journal: Current opinion in pediatrics 20080401
Title: Very very late thrombosis of a sirolimus-eluting stent: does suboptimal stent expansion take its toll even after three years?
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20080401
Title: Simultaneous subacute coronary drug-eluting stent thrombosis in two different vessels of a patient with factor V Leiden mutation.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20080401
Title: Short-period hypoxia increases mouse embryonic stem cell proliferation through cooperation of arachidonic acid and PI3K/Akt signalling pathways.
Journal: Cell proliferation 20080401
Title: Acute allograft rejection and immunosuppression: influence on endogenous melatonin secretion.
Journal: Journal of pineal research 20080401
Title: Temsirolimus downregulates p21 without altering cyclin D1 expression and induces autophagy and synergizes with vorinostat in mantle cell lymphoma.
Journal: Experimental hematology 20080401
Title: Activation and function of the mTORC1 pathway in mast cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20080401
Title: Antiproliferative effect of rapamycin on human T-cell leukemia cell line Jurkat by cell cycle arrest and telomerase inhibition.
Journal: Acta pharmacologica Sinica 20080401
Title: Long-term (>3 Years) outcome and predictors of clinical events after insertion of sirolimus-eluting stent in one or more native coronary arteries (from the Israeli arm of the e-Cypher registry).
Journal: The American journal of cardiology 20080401
Title: Rapamycin and tuberous sclerosis complex: from Easter Island to epilepsy.
Journal: Annals of neurology 20080401
Title: Treatment of drug-eluting stent restenosis: a sandwich may not be the best combo.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401
Title: Stent fracture, an incidental finding or a significant marker of clinical in-stent restenosis?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401
Title: Stent strut fracture: seeing is believing.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401
Title: Survival advantage in Medicare patients receiving drug-eluting stents compared with bare metal stents: real or artefactual?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401
Title: DES editorial. Is there a survival benefit?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401
Title: Effect of lumen narrowing within sirolimus-eluting stents on proximal and distal vessel segments.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20080401
Title: Pharmacokinetics of mycophenolate mofetil and sirolimus in children.
Journal: Therapeutic drug monitoring 20080401
Title: Role of pharmacogenetics of immunosuppressive drugs in organ transplantation.
Journal: Therapeutic drug monitoring 20080401
Title: Toxicodynamic therapeutic drug monitoring of immunosuppressants: promises, reality, and challenges.
Journal: Therapeutic drug monitoring 20080401
Title: The effect of drug-eluting stents on intermediate angiographic and clinical outcomes in diabetic patients: insights from randomized clinical trials.
Journal: American heart journal 20080401
Title: P70 S6 kinase negatively regulates fibroblast growth factor 2-stimulated interleukin-6 synthesis in osteoblasts: function at a point downstream from protein kinase C.
Journal: The Journal of endocrinology 20080401
Title: Effects of cyclosporine, tacrolimus and sirolimus on vascular changes related to immune response.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080401
Title: Regression of pulmonary lymphangioleiomyomatosis (PLAM)-associated retroperitoneal angiomyolipoma post-lung transplantation with rapamycin treatment.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080401
Title: Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy.
Journal: Cancer research 20080401
Title: Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex.
Journal: Annals of neurology 20080401
Title: Rapid activation of Akt2 is sufficient to stimulate GLUT4 translocation in 3T3-L1 adipocytes.
Journal: Cell metabolism 20080401
Title: Treatment options for metastatic renal cell carcinoma: a review.
Journal: The Canadian journal of urology 20080401
Title: Rapamycin prevents the development of nephritis in lupus-prone NZB/W F1 mice.
Journal: Lupus 20080401
Title: Preclinical evidences suggest new treatment options for endocrine disorders: Pasireotide (SOM230) and Everolimus (RAD001).
Journal: Annales d'endocrinologie 20080401
Title: Conversion therapy to everolimus in renal transplant recipients: results after one year.
Journal: Transplantation proceedings 20080401
Title: Drug-eluting stents: present and future.
Journal: Cardiovascular & hematological agents in medicinal chemistry 20080401
Title: Polypyrimidine tract-binding protein is involved in regulation of albumin synthesis in response to food intake.
Journal: Journal of nutritional science and vitaminology 20080401
Title: Results of provisional stenting with a Sirolimus-eluting stent for bifurcation lesion: multicenter study in Japan.
Journal: Journal of cardiology 20080401
Title: [Coronary angioplasty in the real world: the RESTEM registry. Outcome of patients treated with sirolimus-eluting stents].
Journal: Giornale italiano di cardiologia (2006) 20080401
Title: mToR inhibitors-induced proteinuria: mechanisms, significance, and management.
Journal: Transplantation reviews (Orlando, Fla.) 20080401
Title: Drug-eluting versus bare-metal stents in the treatment of patients with ST-segment elevation myocardial infarction.
Journal: JACC. Cardiovascular interventions 20080401
Title: Should we routinely use drug-eluting stents for acute myocardial infarction? Let's wait and see.
Journal: JACC. Cardiovascular interventions 20080401
Title: Stent malapposition after sirolimus-eluting and bare-metal stent implantation in patients with ST-segment elevation myocardial infarction: acute and 9-month intravascular ultrasound results of the MISSION! intervention study.
Journal: JACC. Cardiovascular interventions 20080401
Title: Drug essentials mTOR inhibitors.
Journal: Oncology (Williston Park, N.Y.) 20080401
Title: Human immunodeficiency virus type-1 infection inhibits autophagy.
Journal: AIDS (London, England) 20080330
Title: Intravascular ultrasound findings in patients with restenosis of sirolimus- and paclitaxel-eluting stents.
Journal: International journal of cardiology 20080328
Title: Impact of significant chronic kidney disease on long-term clinical outcomes after drug-eluting stent versus bare metal stent implantation.
Journal: International journal of cardiology 20080328
Title: Impact of immunosuppressive drugs on CD4+CD25+FOXP3+ regulatory T cells: does in vitro evidence translate to the clinical setting?
Journal: Transplantation 20080327
Title: Multicenter, randomized study of the use of everolimus with tacrolimus after renal transplantation demonstrates its effectiveness.
Journal: Transplantation 20080327
Title: Asymmetric dimethylarginine and cardiac allograft vasculopathy progression: modulation by sirolimus.
Journal: Transplantation 20080327
Title: Novel immunosuppression: R348, a JAK3- and Syk-inhibitor attenuates acute cardiac allograft rejection.
Journal: Transplantation 20080327
Title: Overview of the 2007 Food and Drug Administration Circulatory System Devices Panel meeting on the endeavor zotarolimus-eluting coronary stent.
Journal: Circulation 20080325
Title: Sirolimus-eluting cobalt-chromium stents: two-year clinical results from first-in-man study on the Firebird 2 stent.
Journal: Chinese medical journal 20080320
Title: Neointimal coverage of sirolimus-eluting stents 6 months and 12 months after implantation: evaluation by optical coherence tomography.
Journal: Chinese medical journal 20080320
Title: Crush stenting in treating coronary bifurcate lesions: paclitaxel eluting stents versus sirolimus eluting stents.
Journal: Chinese medical journal 20080320
Title: Inflammatory response, drug-eluting stent and restenosis.
Journal: Chinese medical journal 20080320
Title: Delivery of rapamycin by PLGA nanoparticles enhances its suppressive activity on dendritic cells.
Journal: Journal of biomedical materials research. Part A 20080315
Title: Effectiveness of drug-eluting stent implantation for patients with unprotected left main coronary artery stenosis.
Journal: The American journal of cardiology 20080315
Title: Mammalian target of rapamycin repression by 3,3'-diindolylmethane inhibits invasion and angiogenesis in platelet-derived growth factor-D-overexpressing PC3 cells.
Journal: Cancer research 20080315
Title: Biodegradable drug-eluting stents: promises and pitfalls.
Journal: Lancet (London, England) 20080315
Title: Decision time for pancreatic islet-cell transplantation.
Journal: Lancet (London, England) 20080315
Title: A bioabsorbable everolimus-eluting coronary stent system for patients with single de-novo coronary artery lesions (ABSORB): a prospective open-label trial.
Journal: Lancet (London, England) 20080315
Title: Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis.
Journal: Molecular cell 20080314
Title: Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugs.
Journal: British journal of cancer 20080311
Title: Drug-eluting stent thrombosis: results from the multicenter Spanish registry ESTROFA (Estudio ESpañol sobre TROmbosis de stents FArmacoactivos).
Journal: Journal of the American College of Cardiology 20080311
Title: Long-term follow-up evaluation after sirolimus-eluting stent implantation by optical coherence tomography: do uncovered struts persist?
Journal: Journal of the American College of Cardiology 20080304
Title: Chemical imaging of drug eluting coatings: combining surface analysis and confocal Raman microscopy.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20080303
Title: Impact of late incomplete stent apposition after sirolimus-eluting stent implantation on 4-year clinical events: intravascular ultrasound analysis from the multicentre, randomised, RAVEL, E-SIRIUS and SIRIUS trials.
Journal: Heart (British Cardiac Society) 20080301
Title: Subversion of cellular autophagy by Anaplasma phagocytophilum.
Journal: Cellular microbiology 20080301
Title: Components of the Vid30c are needed for the rapamycin-induced degradation of the high-affinity hexose transporter Hxt7p in Saccharomyces cerevisiae.
Journal: FEMS yeast research 20080301
Title: On the participation of mTOR in recognition memory.
Journal: Neurobiology of learning and memory 20080301
Title: Mitogen-stimulated and rapamycin-sensitive glucose transporter 12 targeting and functional glucose transport in renal epithelial cells.
Journal: Endocrinology 20080301
Title: Sirolimus ameliorates the enhanced expression of metalloproteinases in a rat model of autosomal dominant polycystic kidney disease.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080301
Title: Immunosuppression and tumor development in organ transplant recipients: the emerging dualistic role of rapamycin.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20080301
Title: Synergistic effect of mTOR inhibitor rapamycin and fluorouracil in inducing apoptosis and cell senescence in hepatocarcinoma cells.
Journal: Cancer biology & therapy 20080301
Title: Targeting 14-3-3 sensitizes native and mutant BCR-ABL to inhibition with U0126, rapamycin and Bcl-2 inhibitor GX15-070.
Journal: Leukemia 20080301
Title: Interferon beta augments tuberous sclerosis complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human lymphangioleiomyomatosis-derived cell proliferation.
Journal: Molecular pharmacology 20080301
Title: Phospho-S6 ribosomal protein: a potential new predictive sarcoma marker for targeted mTOR therapy.
Journal: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20080301
Title: Synergic antiproliferative and antiangiogenic effects of EGFR and mTor inhibitors on pancreatic cancer cells.
Journal: Biochemical pharmacology 20080301
Title: Sirolimus reduces polycystic liver volume in ADPKD patients.
Journal: Journal of the American Society of Nephrology : JASN 20080301
Title: Pharmacokinetics of sirolimus (rapamycin) in subjects with severe hepatic impairment.
Journal: Journal of clinical pharmacology 20080301
Title: Delta-24-RGD in combination with RAD001 induces enhanced anti-glioma effect via autophagic cell death.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20080301
Title: Human herpesvirus-8 (HHV-8)-associated primary effusion lymphoma in two renal transplant recipients receiving rapamycin.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080301
Title: mTOR signaling contributes to chondrocyte differentiation.
Journal: Developmental dynamics : an official publication of the American Association of Anatomists 20080301
Title: STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25- effector T cells.
Journal: International immunology 20080301
Title: Two-year clinical outcome after implantation of sirolimus-eluting and paclitaxel-eluting stents in diabetic patients.
Journal: European heart journal 20080301
Title: Late incomplete stent apposition after drug-eluting stent implantation: a true risk factor or 'an innocent bystander'?
Journal: Heart (British Cardiac Society) 20080301
Title: Luminal narrowing after sirolimus-eluting stent implantation for in-stent restenosis using intravascular ultrasound.
Journal: American heart journal 20080301
Title: Immediate and long-term outcomes of drug-eluting stent implantation for unprotected left main coronary artery disease: comparison with bare-metal stent implantation.
Journal: American heart journal 20080301
Title: Biological action of rapamycin in renal transplantation.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20080301
Title: Clinical safety of drug-eluting stents in the Korea acute myocardial infarction registry.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20080301
Title: Inflammation and delayed endothelization with overlapping drug-eluting stents in a porcine model of in-stent restenosis.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20080301
Title: Higher incidence and serum levels of minor cardiac biomarker elevation in sirolimus-eluting stent (Cypher) than bare metal stent implantations.
Journal: Coronary artery disease 20080301
Title: Differential outcomes after sirolimus-eluting stent implantation: comparing on-label versus off-label patients in the 'real world'.
Journal: Coronary artery disease 20080301
Title: Exploiting the mammalian target of rapamycin pathway in hematologic malignancies.
Journal: Current opinion in hematology 20080301
Title: Vascular endothelial growth factor protein levels and gene expression in peripheral monocytes after stenting: a randomized comparative study of sirolimus: eluting and bare metal stents.
Journal: European heart journal 20080301
Title: Unprotected left main disease managed with drug-eluting stents: long-term outcome of 100 patients with increased surgical risk.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080301
Title: Outcomes of nonagenarians who undergo percutaneous coronary intervention with drug-eluting stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080301
Title: Percutaneous coronary intervention in nonagenarians: age before beauty?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080301
Title: Stenting unprotected left main: the outcome is not always favorable.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080301
Title: Antitumor activity of rapamycin and octreotide as single agents or in combination in neuroendocrine tumors.
Journal: Endocrine-related cancer 20080301
Title: Temsirolimus, an inhibitor of mammalian target of rapamycin.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080301
Title: Preclinical cancer therapy in a mouse model of neurofibromatosis-1 optic glioma.
Journal: Cancer research 20080301
Title: Damage to polymer of undelivered sirolimus-eluting stents.
Journal: The Journal of invasive cardiology 20080301
Title: Intervention of stenosed right coronary artery and anomalous left main coronary artery: single main coronary trunk.
Journal: The Journal of invasive cardiology 20080301
Title: FK506 binding protein mediates glioma cell growth and sensitivity to rapamycin treatment by regulating NF-kappaB signaling pathway.
Journal: Neoplasia (New York, N.Y.) 20080301
Title: A new trick for an old drug: mTOR inhibitor rapamycin augments the effect of fluorouracil on hepatocellular carcinoma by inducing cell senescence.
Journal: Cancer biology & therapy 20080301
Title: Pharmacological characterization of purified recombinant mTOR FRB-kinase domain using fluorescence-based assays.
Journal: Journal of biomolecular screening 20080301
Title: [Rapamycin combined with donor bone marrow-derived immature dendritic cells induces mouse skin allograft tolerance].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080301
Title: Therapeutic interventions for autosomal dominant polycystic kidney disease.
Journal: Nephrology news & issues 20080301
Title: Rapamycin impairs beta-cell proliferation in vivo.
Journal: Transplantation proceedings 20080301
Title: Influence of rapamycin on rat macrophage viability and chemotaxis toward allogenic pancreatic islet supernates.
Journal: Transplantation proceedings 20080301
Title: Can we maintain immunosuppression avoiding nephrotoxic agents in pancreas transplantation?
Journal: Transplantation proceedings 20080301
Title: Effects of drug-eluting stents on systemic inflammatory response in patients with unstable angina pectoris undergoing percutaneous coronary intervention.
Journal: Heart and vessels 20080301
Title: Impact of sirolimus treatment in kidney allograft recipients with prolonged cold ischemia times: 5-year outcomes.
Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20080301
Title: Fourteen month follow-up angioscopic findings of a sirolimus-eluting stent implanted in a 15-year-old saphenous vein graft.
Journal: International heart journal 20080301
Title: Successful percutaneous treatment of an intraprocedural left main stent thrombosis with the support of an automatic mechanical chest compression device.
Journal: International journal of cardiology 20080227
Title: Poor tolerance of sirolimus in a steroid avoidance regimen for renal transplantation.
Journal: Transplantation 20080227
Title: Pericardial effusion coincident with sirolimus therapy: a review of Wyeth's safety database.
Journal: Transplantation 20080227
Title: Safety and effectiveness of sirolimus-eluting stent implantation for in-stent restenosis of the unprotected left main coronary artery.
Journal: International journal of cardiology 20080220
Title: Two-year clinical outcomes with drug-eluting stents for diabetic patients with de novo coronary lesions: results from a real-world multicenter registry.
Journal: Circulation 20080219
Title: Safe use of raltegravir and sirolimus in an HIV-infected patient with renal impairment after orthotopic liver transplantation.
Journal: AIDS (London, England) 20080219
Title: [Angiogenesis inhibitors for the systemic treatment of metastatic renal cell carcinoma: sunitinib, sorafenib, bevacizumab and temsirolimus].
Journal: Nederlands tijdschrift voor geneeskunde 20080216
Title: Late target lesion revascularization after implantation of sirolimus-eluting stent.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080215
Title: IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes.
Journal: Blood 20080215
Title: A critical role for Lyn in acute myeloid leukemia.
Journal: Blood 20080215
Title: A retroinhibition approach reveals a tumor cell-autonomous response to rapamycin in head and neck cancer.
Journal: Cancer research 20080215
Title: Suppression of Peutz-Jeghers polyposis by targeting mammalian target of rapamycin signaling.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080215
Title: Comparison of a polymer-free rapamycin-eluting stent (YUKON) with a polymer-based paclitaxel-eluting stent (TAXUS) in real-world coronary artery lesions.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080215
Title: Late target lesion revascularization following drug-eluting stents - looking back and forward to success.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080215
Title: Drug for a while, polymer for life: Is it a good solution?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080215
Title: Drug-eluting stenting of unprotected left main coronary artery stenosis in patients with orthotopic heart transplantation: Initial clinical experience.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080215
Title: Prospective comparison of the use of sirolimus and cyclosporine in recipients of a kidney from an expanded criteria donor.
Journal: Transplantation 20080215
Title: Prognostic value of the modified American College of Cardiology/American Heart Association lesion morphology classification for clinical outcome after sirolimus-eluting stent placement (results of the prospective multicenter German Cypher Registry).
Journal: The American journal of cardiology 20080215
Title: Defective TGF-beta signaling sensitizes human cancer cells to rapamycin.
Journal: Oncogene 20080214
Title: Regulation of cyclin D1 expression by mTORC1 signaling requires eukaryotic initiation factor 4E-binding protein 1.
Journal: Oncogene 20080214
Title: Preparation of rapamycin-loaded chitosan/PLA nanoparticles for immunosuppression in corneal transplantation.
Journal: International journal of pharmaceutics 20080212
Title: 'Off-label' stent therapy 2-year comparison of drug-eluting versus bare-metal stents.
Journal: Journal of the American College of Cardiology 20080212
Title: Sirolimus-eluting stents versus bare-metal stents in patients with ST-segment elevation myocardial infarction: 9-month angiographic and intravascular ultrasound results and 12-month clinical outcome results from the MISSION! Intervention Study.
Journal: Journal of the American College of Cardiology 20080212
Title: Development of Kaposi's sarcoma under sirolimus-based immunosuppression and successful treatment with imiquimod.
Journal: Transplant infectious disease : an official journal of the Transplantation Society 20080201
Title: Rhodococcus lung abscess complicating kidney transplantation: successful management by combination antibiotic therapy.
Journal: Transplant infectious disease : an official journal of the Transplantation Society 20080201
Title: Rapamycin inhibits osteoblast proliferation and differentiation in MC3T3-E1 cells and primary mouse bone marrow stromal cells.
Journal: Journal of cellular biochemistry 20080201
Title: Angiographic and 3D intravascular ultrasound assessment of overlapping bare metal stent and three different formulations of drug-eluting stents in patients with diabetes mellitus.
Journal: The international journal of cardiovascular imaging 20080201
Title: Pulmonary lymphangioleiomyomatosis (LAM): progress and current challenges.
Journal: Journal of cellular biochemistry 20080201
Title: Role of ICOS pathway in autoimmune and alloimmune responses in NOD mice.
Journal: Clinical immunology (Orlando, Fla.) 20080201
Title: A randomized exploratory trial of steroid avoidance in renal transplant patients treated with everolimus and low-dose cyclosporine.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080201
Title: Mechanical stimuli of skeletal muscle: implications on mTOR/p70s6k and protein synthesis.
Journal: European journal of applied physiology 20080201
Title: Activation or inactivation of cardiac Akt/mTOR signaling diverges physiological from pathological hypertrophy.
Journal: Journal of cellular physiology 20080201
Title: Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation.
Journal: Blood 20080201
Title: Renal cortex neuronal nitric oxide synthase in response to rapamycin in kidney transplantation.
Journal: Nitric oxide : biology and chemistry 20080201
Title: Amplification at 7q22 targets cyclin-dependent kinase 6 in T-cell lymphoma.
Journal: Leukemia 20080201
Title: Induction of autophagy promotes fusion of multivesicular bodies with autophagic vacuoles in k562 cells.
Journal: Traffic (Copenhagen, Denmark) 20080201
Title: Conversion to sirolimus for chronic allograft dysfunction: long-term results confirm predictive value of proteinuria.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20080201
Title: Effect of calcineurin inhibitors on posaconazole blood levels as measured by the MVista microbiological assay.
Journal: Antimicrobial agents and chemotherapy 20080201
Title: EMAP-II downregulation contributes to the beneficial effects of rapamycin after vascular injury.
Journal: Cardiovascular research 20080201
Title: mTORC1 signaling can regulate growth factor activation of p44/42 mitogen-activated protein kinases through protein phosphatase 2A.
Journal: The Journal of biological chemistry 20080201
Title: Sirolimus eluting stent (Cypher) in patients with diabetes mellitus: results from the German Cypher Stent Registry.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20080201
Title: Coronary in-stent restenosis in diabetic patients after implantation of sirolimus or paclitaxel drug-eluting coronary stents.
Journal: Diabetes & metabolism 20080201
Title: Reduced positive affect (anhedonia) predicts major clinical events following implantation of coronary-artery stents.
Journal: Journal of internal medicine 20080201
Title: The effects of sirolimus on wound healing in dermatologic surgery.
Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20080201
Title: Low-dose mTOR inhibition by rapamycin attenuates progression in anti-thy1-induced chronic glomerulosclerosis of the rat.
Journal: American journal of physiology. Renal physiology 20080201
Title: Rapamycin-conditioned, alloantigen-pulsed dendritic cells promote indefinite survival of vascularized skin allografts in association with T regulatory cell expansion.
Journal: Transplant immunology 20080201
Title: The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model.
Journal: The Journal of clinical investigation 20080201
Title: Three-dimensional compositional analysis of drug eluting stent coatings using cluster secondary ion mass spectrometry.
Journal: Analytical chemistry 20080201
Title: Lentiviral vectors mediate nonimmunosuppressive rapamycin analog-induced production of secreted therapeutic factors in the brain: regulation at the level of transcription and exocytosis.
Journal: Human gene therapy 20080201
Title: Transplantation: it may take two to tango and to treat.
Journal: Immunology and cell biology 20080201
Title: Upregulation of tissue factor expression and thrombogenic activity in human aortic smooth muscle cells by irradiation, rapamycin and paclitaxel.
Journal: International immunopharmacology 20080201
Title: Sicilian DES Registry: prospective in-hospital and 9-month clinical and angiographic follow-up in selected high restenosis risk patients.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20080201
Title: Recurrent restenosis after implantation of sirolimus-eluting stents in aorto-ostial lesions: successful treatment with polytetrafluoroethylene-covered stents.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20080201
Title: Sirolimus-based triple immunosupression with antithymocyte globulin induction in expanded criteria donor kidney transplantation.
Journal: Nephrology (Carlton, Vic.) 20080201
Title: Antiproliferative and proapoptotic effects of rapamycin and celecoxib in malignant melanoma cell lines.
Journal: Oncology reports 20080201
Title: Sirolimus associated pneumonitis after nonmyeloablative peripheral blood stem cell transplant for sickle cell disease.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080201
Title: Incidence of premature discontinuation of antiplatelet therapy after sirolimus-eluting stent implantation.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20080201
Title: Everolimus exposure in cardiac transplant recipients is influenced by concomitant calcineurin inhibitor.
Journal: Therapeutic drug monitoring 20080201
Title: Inhibition of the mammalian target of rapamycin (mTOR) in a case of refractory primary cutaneous anaplastic large cell lymphoma.
Journal: Leukemia & lymphoma 20080201
Title: Effects of rapamycin in liver transplantation.
Journal: Hepatobiliary & pancreatic diseases international : HBPD INT 20080201
Title: Increased expression of the glioma-associated antigen ARF4L after loss of the tumor suppressor PTEN. Laboratory investigation.
Journal: Journal of neurosurgery 20080201
Title: Antiangiogenic therapy with mammalian target of rapamycin inhibitor RAD001 (Everolimus) increases radiosensitivity in solid cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080201
Title: Lymphangioleiomyomatosis: a clinical update.
Journal: Chest 20080201
Title: Pulmonary complications of novel antineoplastic agents for solid tumors.
Journal: Chest 20080201
Title: Multidisciplinary insights on clinical guidance for the use of proliferation signal inhibitors in heart transplantation.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080201
Title: Cyclosporine reduction in the presence of everolimus: 3-month data from a Canadian pilot study of maintenance cardiac allograft recipients.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080201
Title: Expression of signaling mediators downstream of EGF-receptor predict sensitivity to small molecule inhibitors directed against the EGF-receptor pathway.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080201
Title: The potential role of mTOR inhibitors in non-small cell lung cancer.
Journal: The oncologist 20080201
Title: Effects of the mTOR inhibitor sirolimus in patients with hepatocellular and cholangiocellular cancer.
Journal: International journal of clinical oncology 20080201
Title: Drug-eluting stents: a review of current evidence on clinical effectiveness and late complications.
Journal: Scottish medical journal 20080201
Title: Towards defining the role of drug eluting stents.
Journal: Minerva cardioangiologica 20080201
Title: Sirolimus, Tacrolimus and Zotarolimus eluting stents to treat bifurcated lesions: a 7-month clinical outcome comparison.
Journal: Minerva cardioangiologica 20080201
Title: Percutaneous coronary intervention with everolimus-eluting stents (Xience V): systematic review and direct-indirect comparison meta-analyses with paclitaxel-eluting stents (Taxus) and sirolimus-eluting stents (Cypher).
Journal: Minerva cardioangiologica 20080201
Title: Future stent drug delivery systems.
Journal: Minerva cardioangiologica 20080201
Title: Primary and mid-term outcome of sirolimus-eluting stent implantation with angiographic guidance alone.
Journal: Journal of cardiology 20080201
Title: Medial necrosis due to sirolimus-eluting stent implantation in human coronary artery.
Journal: Journal of cardiology 20080201
Title: Late giant coronary aneurysm associated with a fracture of sirolimus eluting stent: a case report.
Journal: Journal of cardiology 20080201
Title: Next-generation drug-eluting stents in coronary artery disease: focus on everolimus-eluting stent (Xience V).
Journal: Vascular health and risk management 20080201
Title: Advances in immunosuppression for pancreas transplantation.
Journal: Current opinion in organ transplantation 20080201
Title: [Long-term efficacy of sirolimus-eluting stents (Cypher) versus bare metal stents for patients with ST-segment elevation myocardial infarction].
Journal: Zhonghua xin xue guan bing za zhi 20080201
Title: [Effects of mTOR inhibitor rapamycin on Smad 3 protein and collagen type I expression in rat myocardial fibroblasts infected with coxsackie virus B 3].
Journal: Zhonghua xin xue guan bing za zhi 20080201
Title: Six-month comparison of coronary endothelial dysfunction associated with sirolimus-eluting stent versus Paclitaxel-eluting stent.
Journal: JACC. Cardiovascular interventions 20080201
Title: Comparison of paclitaxel- and sirolimus-eluting stents in everyday clinical practice: the SORT OUT II randomized trial.
Journal: JAMA 20080130
Title: Effectiveness of drug-eluting stents in real-world patients.
Journal: JAMA 20080130
Title: Long-term survival of limb allografts induced by pharmacologically conditioned, donor alloantigen-pulsed dendritic cells without maintenance immunosuppression.
Journal: Transplantation 20080127
Title: Comparison of sirolimus alone with sirolimus plus tacrolimus in type 1 diabetic recipients of cultured islet cell grafts.
Journal: Transplantation 20080127
Title: Sympathetic dystrophy associated with sirolimus therapy.
Journal: Transplantation 20080127
Title: Angioplasty for the late stent thrombosis, the new technical challenge: a single centre experience.
Journal: International journal of cardiology 20080124
Title: Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR.
Journal: Oncogene 20080124
Title: Concerns in the SESAMI trial.
Journal: Journal of the American College of Cardiology 20080122
Title: mTOR: the mammalian target of replication.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080120
Title: Phase I trial of the novel mammalian target of rapamycin inhibitor deforolimus (AP23573; MK-8669) administered intravenously daily for 5 days every 2 weeks to patients with advanced malignancies.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080120
Title: Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys.
Journal: Journal of the National Cancer Institute 20080116
Title: Surface immobilization of chondroitin 6-sulfate/heparin multilayer on stainless steel for developing drug-eluting coronary stents.
Journal: Colloids and surfaces. B, Biointerfaces 20080115
Title: A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin.
Journal: Human molecular genetics 20080115
Title: Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival.
Journal: Blood 20080115
Title: Rapamycin inhibits PAI-1 expression and reduces interstitial fibrosis and glomerulosclerosis in chronic allograft nephropathy.
Journal: Transplantation 20080115
Title: Rapamycin, but not cyclosporine or FK506, alters natural killer cell function.
Journal: Transplantation 20080115
Title: Mammalian target of rapamycin is the key effector of phosphatidylinositol-3-OH-initiated proliferative signals in the thyroid follicular epithelium.
Journal: Cancer research 20080115
Title: Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway.
Journal: The Journal of biological chemistry 20080111
Title: Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis.
Journal: The New England journal of medicine 20080110
Title: Efficacy of sirolimus in treating tuberous sclerosis and lymphangioleiomyomatosis.
Journal: The New England journal of medicine 20080110
Title: Sirolimus therapy in tuberous sclerosis or sporadic lymphangioleiomyomatosis.
Journal: The New England journal of medicine 20080110
Title: TORC1 is essential for NF1-associated malignancies.
Journal: Current biology : CB 20080108
Title: Effects of sirolimus-eluting stent on calcified coronary lesions.
Journal: Chinese medical journal 20080105
Title: Coupling of mammalian target of rapamycin with phosphoinositide 3-kinase signaling pathway regulates protein phosphatase 2A- and glycogen synthase kinase-3 -dependent phosphorylation of Tau.
Journal: The Journal of biological chemistry 20080104
Title: Refeeding and insulin activate the AKT/p70S6 kinase pathway without affecting IRS1 tyrosine phosphorylation in chicken muscle.
Journal: Domestic animal endocrinology 20080101
Title: Pharmacometrics and delivery of novel nanoformulated PEG-b-poly(epsilon-caprolactone) micelles of rapamycin.
Journal: Cancer chemotherapy and pharmacology 20080101
Title: Can mTOR inhibitors reduce the risk of late kidney allograft failure?
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20080101
Title: Plasticity of ovarian cancer cell SKOV3ip and vasculogenic mimicry in vivo.
Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20080101
Title: Are impaired endothelial progenitor cells involved in the processes of late in-stent thrombosis and re-endothelialization of drug-eluting stents?
Journal: Medical hypotheses 20080101
Title: Mammalian target of rapamycin (mTOR) inhibition activates phosphatidylinositol 3-kinase/Akt by up-regulating insulin-like growth factor-1 receptor signaling in acute myeloid leukemia: rationale for therapeutic inhibition of both pathways.
Journal: Blood 20080101
Title: Adjuvant conversion to sirolimus in liver transplant patients with recurrent hepatocellular carcinoma - preliminary results.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20080101
Title: The role of cell signaling in poxvirus tropism: the case of the M-T5 host range protein of myxoma virus.
Journal: Biochimica et biophysica acta 20080101
Title: Head-to-head comparison of sirolimus- and paclitaxel-eluting stent in the same diabetic patient with multiple coronary artery lesions: a prospective, randomized, multicenter study.
Journal: Diabetes care 20080101
Title: Role of mTOR in physiology and pathology of the nervous system.
Journal: Biochimica et biophysica acta 20080101
Title: Association study of ABCB1 and CYP3A5 gene polymorphisms with sirolimus trough concentration and dose requirements in Chinese renal transplant recipients.
Journal: Biopharmaceutics & drug disposition 20080101
Title: Translational activation of 5'-TOP mRNA in pressure overload myocardium.
Journal: Basic research in cardiology 20080101
Title: Neointimal expression of rapamycin receptor FK506-binding protein FKBP12: postinjury animal and human in-stent restenosis tissue characteristics.
Journal: Journal of vascular research 20080101
Title: Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells.
Journal: Blood 20080101
Title: Simultaneous hybrid coronary revascularization using totally endoscopic left internal mammary artery bypass grafting and placement of rapamycin eluting stents in the same interventional session. The COMBINATION pilot study.
Journal: Cardiology 20080101
Title: Myxoma virus oncolysis of primary and metastatic B16F10 mouse tumors in vivo.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20080101
Title: Octreotide and the mTOR inhibitor RAD001 (everolimus) block proliferation and interact with the Akt-mTOR-p70S6K pathway in a neuro-endocrine tumour cell Line.
Journal: Neuroendocrinology 20080101
Title: The oral mTOR inhibitor RAD001 (everolimus) in combination with letrozole in patients with advanced breast cancer: results of a phase I study with pharmacokinetics.
Journal: European journal of cancer (Oxford, England : 1990) 20080101
Title: Novel methods for tracking long-term maintenance immunosuppression regimens.
Journal: Clinical journal of the American Society of Nephrology : CJASN 20080101
Title: Comparison of vascular response to zotarolimus-eluting stent versus sirolimus-eluting stent: intravascular ultrasound results from ENDEAVOR III.
Journal: American heart journal 20080101
Title: Insulin and IGF-1 enhance the expression of the neuronal monocarboxylate transporter MCT2 by translational activation via stimulation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin pathway.
Journal: The European journal of neuroscience 20080101
Title: Restenosis of the CYPHER-Select, TAXUS-Express, and Polyzene-F nanocoated cobalt-chromium stents in the minipig coronary artery model.
Journal: Cardiovascular and interventional radiology 20080101
Title: Ex vivo rapamycin generates apoptosis-resistant donor Th2 cells that persist in vivo and prevent hemopoietic stem cell graft rejection.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20080101
Title: Huge right atrial thrombus 6 years after heart transplantation.
Journal: The Annals of thoracic surgery 20080101
Title: Clinical outcomes after heterogeneous overlap stenting with drug-eluting stents and bare-metal stents for de novo coronary artery narrowings.
Journal: The American journal of cardiology 20080101
Title: Short- and long-term outcomes after stent-assisted percutaneous treatment of saphenous vein grafts in the drug-eluting stent era.
Journal: The American journal of cardiology 20080101
Title: Results of percutaneous coronary intervention of the unprotected left main coronary artery in 143 patients and comparison of 30-day mortality to results of coronary artery bypass grafting.
Journal: The American journal of cardiology 20080101
Title: Sirolimus-eluting stents vs bare metal stents for coronary intervention in Japanese patients with renal failure on hemodialysis.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20080101
Title: Late stent thrombosis in patients receiving ticlopidine and aspirin after sirolimus-eluting stent implantation.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20080101
Title: Evaluation of antileukaemic effects of rapamycin in patients with imatinib-resistant chronic myeloid leukaemia.
Journal: European journal of clinical investigation 20080101
Title: Changes in CCR2 chemokine receptor expression and plasma MCP-1 concentration after the implantation of bare metal stents versus sirolimus-eluting stents in patients with stable angina.
Journal: Internal medicine (Tokyo, Japan) 20080101
Title: Sirolimus-induced inflammatory papules with acquired reactive perforating collagenosis.
Journal: Dermatology (Basel, Switzerland) 20080101
Title: San Antonio Breast Cancer Symposium.
Journal: The Lancet. Oncology 20080101
Title: Impact of lesion calcification on clinical and angiographic outcome after sirolimus-eluting stent implantation in real-world patients.
Journal: Cardiovascular revascularization medicine : including molecular interventions 20080101
Title: Drug-eluting stents are associated with similar cardiovascular outcomes when compared to bare metal stents in the setting of acute myocardial infarction.
Journal: Cardiovascular revascularization medicine : including molecular interventions 20080101
Title: Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma.
Journal: PLoS medicine 20080101
Title: Incorporating molecular tools into early-stage clinical trials.
Journal: PLoS medicine 20080101
Title: Calcineurin inhibitor-sparing regimens in solid organ transplantation: focus on improving renal function and nephrotoxicity.
Journal: Clinical transplantation 20080101
Title: A sensitive high-throughput HPLC assay for simultaneous determination of everolimus and clobetasol propionate.
Journal: Journal of chromatographic science 20080101
Title: Can the wound healing response of human skin be modulated after laser treatment and the effects of exposure extended? Implications on the combined use of the pulsed dye laser and a topical angiogenesis inhibitor for treatment of port wine stain birthmarks.
Journal: Lasers in surgery and medicine 20080101
Title: Tuberous sclerosis: a primary pathology of astrocytes?
Journal: Epilepsia 20080101
Title: Topical rapamycin inhibits tuberous sclerosis tumor growth in a nude mouse model.
Journal: BMC dermatology 20080101
Title: [Molecular targeted therapy for renal cell carcinoma].
Journal: Hinyokika kiyo. Acta urologica Japonica 20080101
Title: The effect of sirolimus in the development of chronic allograft nephropathy.
Journal: Transplantation proceedings 20080101
Title: The mTOR inhibitor everolimus attenuates the time course of chronic anti-Thy1 nephritis in the rat.
Journal: Nephron. Experimental nephrology 20080101
Title: Hsf1 activation inhibits rapamycin resistance and TOR signaling in yeast revealed by combined proteomic and genetic analysis.
Journal: PloS one 20080101
Title: Comparison of long-term angiographic follow-up after sirolimus-eluting stent and bare-metal stent implantation.
Journal: Internal medicine (Tokyo, Japan) 20080101
Title: Obesity following kidney transplantation and steroid avoidance immunosuppression.
Journal: Clinical transplantation 20080101
Title: Early, abrupt conversion of de novo renal transplant patients from cyclosporine to everolimus: results of a pilot study.
Journal: Clinical transplantation 20080101
Title: mTOR inhibitors and calcineurin inhibitors do not affect adhesion molecule expression of human macro- and microvascular endothelial cells.
Journal: Journal of vascular research 20080101
Title: SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts.
Journal: PloS one 20080101
Title: Mycophenolate mofetil vs. sirolimus in kidney transplant recipients receiving tacrolimus-based immunosuppressive regimen.
Journal: Clinical transplantation 20080101
Title: Use of low dose tacrolimus, mycophenolate mofetil and maintenance IL-2 receptor blockade in an islet transplant recipient.
Journal: Clinical transplantation 20080101
Title: Generalized lymphedema in a sirolimus-treated renal transplant patient.
Journal: Clinical transplantation 20080101
Title: The combination of sirolimus and cyclosporine does not delay initial renal graft function recovery.
Journal: Renal failure 20080101
Title: [Rapamycin and lymphangiogenesis: side effect or treatment result?].
Journal: Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20080101
Title: Solution structure of the Legionella pneumophila Mip-rapamycin complex.
Journal: BMC structural biology 20080101
Title: Pathobiology and prognosis of chromophobe renal cell carcinoma.
Journal: Urologic oncology 20080101
Title: Temsirolimus: in advanced renal cell carcinoma.
Journal: Drugs 20080101
Title: The PI-3kinase pathway in hematopoietic stem cells and leukemia-initiating cells: a mechanistic difference between normal and cancer stem cells.
Journal: Blood cells, molecules & diseases 20080101
Title: Crush stenting with paclitaxel-eluting or sirolimus-eluting stents for the treatment of coronary bifurcation lesions.
Journal: Angiology 20080101
Title: Characterization of the Rheb-mTOR signaling pathway in mammalian cells: constitutive active mutants of Rheb and mTOR.
Journal: Methods in enzymology 20080101
Title: Total synthesis studies on macrocyclic pipecolic acid natural products: FK506, the antascomicins and rapamycin.
Journal: Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques 20080101
Title: Drug-eluting stents - what should be improved?
Journal: Annals of medicine 20080101
Title: Persistent peritoneal dialysis catheter exit-site leak in a patient receiving maintenance immunosuppression with sirolimus.
Journal: Clinical transplantation 20080101
Title: The evolution of immunosuppressant therapy in renal transplantation.
Journal: Drugs 20080101
Title: Malignancy in kidney transplant recipients.
Journal: Drugs 20080101
Title: Mechanisms and management of proteinuria in kidney transplant patients.
Journal: Drugs 20080101
Title: Sirolimus use in recipients of expanded criteria donor kidneys.
Journal: Drugs 20080101
Title: Better understanding of ADPKD results in potential new treatment options: ready for the cure?
Journal: Journal of nephrology 20080101
Title: Comparison of bare-metal and sirolimus- or paclitaxel-eluting stents for aorto-ostial coronary disease.
Journal: Cardiology 20080101
Title: A preliminary experience report: Drug-eluting stents versus coronary artery bypass surgery in patients with a single lesion in the proximal left anterior descending artery suffering from diabetes mellitus and chronic stable angina.
Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20080101
Title: The mTOR signaling network: insights from its role during embryonic development.
Journal: Current medicinal chemistry 20080101
Title: Pharmacokinetics of mycophenolic acid, tacrolimus and sirolimus after gastric bypass surgery in end-stage renal disease and transplant patients: a pilot study.
Journal: Clinical transplantation 20080101
Title: Neovascular age-related macular degeneration: potential therapies.
Journal: Drugs 20080101
Title: Successful treatment of a coronary cameral fistula secondary to elective sirolimus-eluting stent implantation.
Journal: Cardiovascular revascularization medicine : including molecular interventions 20080101
Title: Efficacy and safety of drug-eluting stents in long-term follow-up.
Journal: Internal medicine (Tokyo, Japan) 20080101
Title: Stability of sirolimus and everolimus measured by immunoassay techniques in whole blood samples from kidney transplant patients.
Journal: International journal of immunopathology and pharmacology 20080101
Title: Activation of the mammalian target of rapamycin complex 1 is both necessary and sufficient to stimulate eukaryotic initiation factor 2Bvarepsilon mRNA translation and protein synthesis.
Journal: The international journal of biochemistry & cell biology 20080101
Title: Resistance exercise biology: manipulation of resistance exercise programme variables determines the responses of cellular and molecular signalling pathways.
Journal: Sports medicine (Auckland, N.Z.) 20080101
Title: Sirolimus induced dyslipidemia in tacrolimus based vs. tacrolimus free immunosuppressive regimens in renal transplant recipients.
Journal: Annals of transplantation 20080101
Title: Meta-analysis shows similar risk of thrombosis after drug-eluting stent, bare-metal stent, or angioplasty.
Journal: Endothelium : journal of endothelial cell research 20080101
Title: Rapamycin delays growth of Wnt-1 tumors in spite of suppression of host immunity.
Journal: BMC cancer 20080101
Title: On the action of cyclosporine A, rapamycin and tacrolimus on M. avium including subspecies paratuberculosis.
Journal: PloS one 20080101
Title: Effect of rifampicin to inhibit rapamycin-induced autophagy via the suppression of protein phosphatase 2A activity.
Journal: Immunopharmacology and immunotoxicology 20080101
Title: An update on the medical therapy of advanced metastatic renal cell carcinoma.
Journal: Scandinavian journal of urology and nephrology 20080101
Title: Comparison between a liquid chromatography-tandem mass spectrometry assay and a fluorescent polarization immunoassay to measure whole blood everolimus concentration in heart and renal transplantations.
Journal: Journal of clinical laboratory analysis 20080101
Title: IGF-I receptor inhibition combined with rapamycin or temsirolimus inhibits neuroblastoma cell growth.
Journal: Anticancer research 20080101
Title: Nonimmunosuppressive effects of mammalian target of rapamycin inhibitors.
Journal: Transplantation reviews (Orlando, Fla.) 20080101
Title: Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer.
Journal: BMC genomics 20080101
Title: Negative inotropic effect of rapamycin on isolated human cardiomyocytes.
Journal: The Journal of international medical research 20080101
Title: Mammalian target of rapamycin as a target in hematological malignancies.
Journal: Current problems in cancer 20080101
Title: Selective corticosteroid and calcineurin-inhibitor withdrawal after pancreas-kidney transplantation utilizing thymoglobulin induction and sirolimus maintenance therapy.
Journal: Clinical transplantation 20080101
Title: [To stay immature: the first step to tolerate?].
Journal: Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20080101
Title: Effects of everolimus monotherapy on hematological parameters and iron homeostasis in de novo liver transplant recipients: preliminary results.
Journal: Transplantation proceedings 20080101
Title: Sirolimus therapy in liver transplant patients: an initial experience at a single center.
Journal: Transplantation proceedings 20080101
Title: [Role of PTEN protein in multidrug resistance of prostate cancer cells].
Journal: Molekuliarnaia biologiia 20080101
Title: Current management of tuberous sclerosis complex.
Journal: Paediatric drugs 20080101
Title: TOR signaling in fission yeast.
Journal: Critical reviews in biochemistry and molecular biology 20080101
Title: Drug eluting and bare metal stents in people with and without diabetes: collaborative network meta-analysis.
Journal: BMJ (Clinical research ed.) 20080101
Title: The South African branch of the Crossroads Institute celebrates it second birthday.
Journal: Cardiovascular journal of Africa 20080101
Title: [Tirofiban or abciximab and sirolimus-eluting or bare metal uncoated stents in primary percutaneous coronary intervention for acute myocardial infarction: results of MULTISTRATEGY trial].
Journal: Kardiologiia 20080101
Title: Clinical results of drug eluting stents compared to bare metal stents for patients with ST elevation acute myocardial infarction.
Journal: Acute cardiac care 20080101
Title: Influence of interactions between immunosuppressive drugs on therapeutic drug monitoring.
Journal: Annals of transplantation 20080101
Title: Orally administered rapamycin, dacarbazine or both for treatment of human melanoma evaluated in severe combined immunodeficiency mice.
Journal: Pharmacology 20080101
Title: Monotherapy with anti-LFA-1 monoclonal antibody promotes long-term survival of rat islet xenografts.
Journal: Cell transplantation 20080101
Title: Quantification of sirolimus and everolimus by immunoassay techniques: test specificity and cross-reactivity evaluation.
Journal: International journal of immunopathology and pharmacology 20080101
Title: Signaling inhibitors in metastatic renal cell carcinoma.
Journal: Cancer journal (Sudbury, Mass.) 20080101
Title: From Easter Island to coated coronary stents: a remarkable saga.
Journal: Journal of the Medical Association of Georgia 20080101
Title: A rapid liquid chromatography-tandem mass spectrometry analysis of whole blood sirolimus using turbulent flow technology for online extraction.
Journal: Clinical chemistry and laboratory medicine 20080101
Title: TOR regulates cell death induced by telomere dysfunction in budding yeast.
Journal: PloS one 20080101
Title: Efficacy of rapamycin in scleroderma: a case study.
Journal: Lymphatic research and biology 20080101
Title: Effects of everolimus as an antiproliferative agent on regression of encapsulating peritoneal sclerosis in a rat model.
Journal: Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20080101
Title: Failure of systematic error detection with internal quality control program.
Journal: Annals of clinical and laboratory science 20080101
Title: [Chronic allograft dysfunction: role of immunosuppressive treatment].
Journal: Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20080101
Title: Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability.
Journal: Molecular cancer 20080101
Title: [ASCO 2008. Bevacizumab in advanced renal carcinoma].
Journal: Tumori 20080101
Title: PTEN and rapamycin inhibiting the growth of K562 cells through regulating mTOR signaling pathway.
Journal: Journal of experimental & clinical cancer research : CR 20080101
Title: Effect of intestinal and hepatic first-pass extraction on the pharmacokinetics of everolimus in rats.
Journal: Drug metabolism and pharmacokinetics 20080101
Title: [Experience with primary coronary angioplasty in management of patients suffering from acute myocardial infarction].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20080101
Title: [Problem of restenosis inside stents with an antiproliferative coating].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20080101
Title: Methods to investigate autophagy during starvation and regeneration in hydra.
Journal: Methods in enzymology 20080101
Title: mTOR inhibition sensitizes gastric cancer to alkylating chemotherapy in vivo.
Journal: Anticancer research 20080101
Title: A case of complete revascularization with nine sirolimus eluting stents.
Journal: Indian heart journal 20080101
Title: Sirolimus-loaded polyurethane graft for hemodialysis access in sheep.
Journal: Vascular 20080101
Title: Two-year (mid-term) results for unprotected left main coronary artery percutaneous interventions with drug-eluting stents.
Journal: Indian heart journal 20080101
Title: Preclinical and early clinical experience with a biodegradable polymer-based, rapamycin-eluting, Indian drug-eluting coronary stent: the BIO-RAPID study.
Journal: Indian heart journal 20080101
Title: [Experience in using stents with an antiproliferative coating in treatment of stenoses and occlusions of coronary arteries. Review of the literature].
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20080101
Title: Chemically induced and light-independent cryptochrome photoreceptor activation.
Journal: Molecular plant 20080101
Title: Rapamycin impairs in vivo proliferation of islet beta-cells.
Journal: Transplantation 20071227
Title: Long-term limb allograft survival using a short course of anti-CD45RB monoclonal antibody, LF 15-0195, and rapamycin in a mouse model.
Journal: Transplantation 20071227
Title: Apoptosis and autophagy as mechanisms of dinoflagellate symbiont release during cnidarian bleaching: every which way you lose.
Journal: Proceedings. Biological sciences 20071222
Title: Targeted drugs for metastatic renal cell carcinoma.
Journal: Lancet (London, England) 20071222
Title: Safety of drug-eluting stents: demystifying network meta-analysis.
Journal: Lancet (London, England) 20071222
Title: The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells.
Journal: The Journal of biological chemistry 20071221
Title: Reduced exposure to calcineurin inhibitors in renal transplantation.
Journal: The New England journal of medicine 20071220
Title: Balancing efficacy and toxicity in kidney-transplant immunosuppression.
Journal: The New England journal of medicine 20071220
Title: Advancing the knowledge base on the efficacy-safety ratio with drug-eluting stents contributions from the European Society of Cardiology Congress, Vienna, Austria, September 1-5, 2007.
Journal: Journal of the American College of Cardiology 20071218
Title: Temsirolimus (Torisel) for advanced renal cell carcinoma.
Journal: The Medical letter on drugs and therapeutics 20071217
Title: Angiographic and intravascular ultrasound study of the effects of overlapping sirolimus- and paclitaxel-eluting stents: comparison with same drug-eluting overlapping stents.
Journal: International journal of cardiology 20071215
Title: Comparison of bypass surgery with drug-eluting stents for diabetic patients with multivessel disease.
Journal: International journal of cardiology 20071215
Title: Determination of the rate constants for the FK506 binding protein/rapamycin interaction using surface plasmon resonance: an alternative sensor surface for Ni2+-nitrilotriacetic acid immobilization of His-tagged proteins.
Journal: Analytical biochemistry 20071215
Title: The selectivity of protein kinase inhibitors: a further update.
Journal: The Biochemical journal 20071215
Title: Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells.
Journal: International immunopharmacology 20071215
Title: A lower incidence of cytomegalovirus infection in de novo heart transplant recipients randomized to everolimus.
Journal: Transplantation 20071215
Title: The mTOR inhibitor everolimus induces proteinuria and renal deterioration in the remnant kidney model in the rat.
Journal: Transplantation 20071215
Title: Pharmacokinetic and tumor distribution characteristics of temsirolimus in patients with recurrent malignant glioma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20071215
Title: Rapamycin promotes vascular smooth muscle cell differentiation through insulin receptor substrate-1/phosphatidylinositol 3-kinase/Akt2 feedback signaling.
Journal: The Journal of biological chemistry 20071207
Title: Minor contribution of an internal ribosome entry site in the 5'-UTR of ornithine decarboxylase mRNA on its translation.
Journal: Biochemical and biophysical research communications 20071207
Title: Sirolimus-induced drug fever and ciclosporin-induced leukencephalopathia with seizures in one liver transplant recipient.
Journal: World journal of gastroenterology 20071207
Title: Conversion to sirolimus as primary immunosuppression attenuates the progression of allograft vasculopathy after cardiac transplantation.
Journal: Circulation 20071204
Title: Sirolimus and cardiac transplantation: is it the 'magic bullet'?
Journal: Circulation 20071204
Title: Decreased levels of hypoxic cells in gefitinib treated ER+ HER-2 overexpressing MCF-7 breast cancer tumors are associated with hyperactivation of the mTOR pathway: therapeutic implications for combination therapy with rapamycin.
Journal: Breast cancer research and treatment 20071201
Title: Pharmacokinetics, safety, and efficacy of mycophenolate mofetil in combination with sirolimus or ciclosporin in renal transplant patients.
Journal: British journal of clinical pharmacology 20071201
Title: Sirolimus (rapamycin): from the soil of Easter Island to a bright future.
Journal: Journal of the American Academy of Dermatology 20071201
Title: Pneumonitis associated with sirolimus: clinical characteristics, risk factors and outcome--a single-centre experience and review of the literature.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20071201
Title: Efficacy of reduced-dose sirolimus-eluting stents in the human coronary artery: serial IVUS analysis of neointimal hyperplasia and luminal dimension.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071201
Title: Long-term clinical follow-up of sirolimus-eluting (CYPHER) coronary stents in the treatment of instent restenosis in an unselected population.
Journal: Heart, lung & circulation 20071201
Title: Functional and phenotypic characteristics of CD4+CD25highFoxp3+ Treg clones obtained from peripheral blood of patients with cancer.
Journal: International journal of cancer 20071201
Title: Proteinuria after kidney transplantation, relationship to allograft histology and survival.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071201
Title: Clinically relevant immunosuppressants influence UVB-induced tumor size through effects on inflammation and angiogenesis.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071201
Title: Immunosuppressant pharmacokinetics and dosing modifications in HIV-1 infected liver and kidney transplant recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071201
Title: Genetically encoded molecules for inducibly inactivating CaV channels.
Journal: Nature chemical biology 20071201
Title: Effects of rapamycin on gene expression, morphology, and electrophysiological properties of rat hippocampal neurons.
Journal: Epilepsy research 20071201
Title: Immunosuppressive agents: effects on glucose and lipid metabolism.
Journal: Endocrinology and metabolism clinics of North America 20071201
Title: Regulation of elongation phase of mRNA translation in diabetic nephropathy: amelioration by rapamycin.
Journal: The American journal of pathology 20071201
Title: Serial long-term evaluation of neointimal stent coverage and thrombus after sirolimus-eluting stent implantation by use of coronary angioscopy.
Journal: Heart (British Cardiac Society) 20071201
Title: Strut fracture of a sirolimus-eluting stent at the ostium of the right coronary artery.
Journal: Heart (British Cardiac Society) 20071201
Title: Impact of metabolic syndrome on clinical and angiographic outcome after sirolimus-eluting stent implantation.
Journal: Coronary artery disease 20071201
Title: RESTEM: a percutaneous coronary intervention 'real world' registry in the drug-eluting stent era.
Journal: Coronary artery disease 20071201
Title: Chemical genetic modification of Ca2+ channel activity.
Journal: Nature chemical biology 20071201
Title: Cost-effectiveness of sirolimus-eluting stents compared with vascular brachytherapy for the treatment of in-stent restenosis.
Journal: American heart journal 20071201
Title: Comparison of effects of telmisartan and valsartan on late lumen loss and inflammatory markers after sirolimus-eluting stent implantation in hypertensive patients.
Journal: The American journal of cardiology 20071201
Title: Long-term clinical benefit of sirolimus-eluting stents compared to bare metal stents in the treatment of saphenous vein graft disease.
Journal: Journal of interventional cardiology 20071201
Title: Crossreactivity of isolated everolimus metabolites with the Innofluor Certican immunoassay for therapeutic drug monitoring of everolimus.
Journal: Therapeutic drug monitoring 20071201
Title: A randomized controlled trial of late conversion from calcineurin inhibitor (CNI)-based to sirolimus-based immunosuppression in liver transplant recipients with impaired renal function.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20071201
Title: Analysis of bifurcation lesions treated with novel drug-eluting dedicated bifurcation stent system: intravascular ultrasound results of the AXXESS PLUS trial.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071201
Title: Percutaneous coronary intervention in the 21st century - making surgeons irrelevant?
Journal: Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine 20071201
Title: Targeting protein translation in human non small cell lung cancer via combined MEK and mammalian target of rapamycin suppression.
Journal: Cancer research 20071201
Title: Pravastatin induces rat aortic endothelial cell proliferation and migration via activation of PI3K/Akt/mTOR/p70 S6 kinase signaling.
Journal: Journal of pharmacological sciences 20071201
Title: Small-molecule and antibody approaches to molecular chemotherapy of primary brain tumors.
Journal: Current opinion in investigational drugs (London, England : 2000) 20071201
Title: Sirolimus-eluting versus bare-metal stents for the reduction of coronary restenosis: 18-month angiographic results from the GERSHWIN Study.
Journal: Herz 20071201
Title: Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20071201
Title: [mTOR signal pathway and its inhibitors in antitumor therapy: a review].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20071201
Title: [Rapamycin affects eIF- 4E expression in rat myocardial fibroblasts infected by Coxsackievirus B3].
Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20071201
Title: Proliferation signal inhibitors in transplantation: questions at the cutting edge of everolimus therapy.
Journal: Transplantation proceedings 20071201
Title: Statins benefit outcomes of renal transplant recipients on a sirolimus-cyclosporine regimen.
Journal: Transplantation proceedings 20071201
Title: Posttransplantation conversion to sirolimus-based immunosuppression: a single center experience.
Journal: Transplantation proceedings 20071201
Title: Economic evaluation of everolimus and mycophenolate mofetil versus azathioprine in de novo heart transplantation.
Journal: Transplantation proceedings 20071201
Title: Anti-CD25 mAb, anti-IL2 mAb, and IL2 block tolerance induction through anti-CD154 mAb and rapamycin in xenogeneic islet transplantation.
Journal: Transplantation proceedings 20071201
Title: An unusual presentation of sirolimus associated cough in a renal transplant recipient.
Journal: Transplantation proceedings 20071201
Title: Interstitial pneumonitis associated with sirolimus in liver transplantation: a case report.
Journal: Transplantation proceedings 20071201
Title: Switch to everolimus for sirolimus-induced pneumonitis in a liver transplant recipient--not all proliferation signal inhibitors are the same: a case report.
Journal: Transplantation proceedings 20071201
Title: [Therapeutic effect of sirolimus against chronic allograft nephropathy in kidney transplant recipients].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20071201
Title: Acute thrombosis of a mesenteric artery drug-eluting stent following clopidogrel cessation.
Journal: Vascular and endovascular surgery 20071201
Title: Characterization of late incomplete stent apposition: a comparison among bare-metal stents, intracoronary radiation and sirolimus-eluting stents.
Journal: The Journal of invasive cardiology 20071201
Title: The Cairo kidney center protocol for rapamycin-based sequential immunosuppression in kidney transplant recipients: 2-year outcomes.
Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20071201
Title: New strategies for the treatment of metastatic bone disease.
Journal: Clinical breast cancer 20071201
Title: [Synergistic effect of rapamycin (RPM) and PD98059 on cell cycle and mTOR signal transduction in human colorectal cancer cells].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20071201
Title: Clinically significant proteinuria following the administration of sirolimus to renal transplant recipients.
Journal: Drug metabolism letters 20071201
Title: mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.
Journal: Nature 20071129
Title: Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53.
Journal: The EMBO journal 20071128
Title: Gender-specific outcomes after sirolimus-eluting stent implantation.
Journal: Journal of the American College of Cardiology 20071127
Title: Peeling-off labels mounting evidence for benefit of drug-eluting stents with off-label use.
Journal: Journal of the American College of Cardiology 20071120
Title: Sirolimus-eluting stent treatment as buffer for inflamed lesions identified by serum marker estimation. The STABILISE pilot study.
Journal: International journal of cardiology 20071115
Title: Steroid-free maintenance immunosuppression with rapamune and low-dose neoral in pancreas transplant recipients.
Journal: Transplantation 20071115
Title: Drug eluting stents versus coronary artery bypass surgery in patients with isolated proximal lesion in left anterior descending artery suffering from chronic stable angina.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071115
Title: Cell signaling. mTOR, unleashed.
Journal: Science (New York, N.Y.) 20071109
Title: Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38.
Journal: Science (New York, N.Y.) 20071109
Title: Intravascular drug release kinetics dictate arterial drug deposition, retention, and distribution.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20071106
Title: Cost-effectiveness of drug-eluting stents in patients at high or low risk of major cardiac events in the Basel Stent KostenEffektivitäts Trial (BASKET): an 18-month analysis.
Journal: Lancet (London, England) 20071103
Title: Sirolimus blocks the accumulation of hyaluronan (HA) by arterial smooth muscle cells and reduces monocyte adhesion to the ECM.
Journal: Atherosclerosis 20071101
Title: Preparation and characterization of rapamycin-loaded PLGA coating stent.
Journal: Journal of materials science. Materials in medicine 20071101
Title: Blockade of chronic graft-versus-host disease by alloantigen-induced CD4+CD25+Foxp3+ regulatory T cells in nonlymphopenic hosts.
Journal: Journal of leukocyte biology 20071101
Title: A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase.
Journal: Cell death and differentiation 20071101
Title: Everolimus-associated interstitial pneumonitis in a patient with a heart transplant.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20071101
Title: Sirolimus versus cyclosporine in kidney recipients receiving thymoglobulin, mycophenolate mofetil and a 6-month course of steroids.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071101
Title: Molecular targeted therapy of head and neck cancer: review and clinical development challenges.
Journal: European journal of cancer (Oxford, England : 1990) 20071101
Title: Sirolimus in chronic allograft nephropathy in pediatric recipients.
Journal: Pediatric transplantation 20071101
Title: Pharmacokinetic profile of temsirolimus with concomitant administration of cytochrome p450-inducing medications.
Journal: Journal of clinical pharmacology 20071101
Title: Randomized trial of rapamycin- and paclitaxel-eluting stents with identical biodegradable polymeric coating and design.
Journal: European heart journal 20071101
Title: RyR1-specific requirement for depolarization-induced Ca2+ sparks in urinary bladder smooth muscle.
Journal: Journal of cell science 20071101
Title: Implantation of sirolimus-eluting stents in saphenous vein grafts is associated with high clinical follow-up event rates compared with treatment of native vessels.
Journal: Coronary artery disease 20071101
Title: Serial long-term evaluation of neointimal stent coverage and thrombus after sirolimus-eluting stent implantation by use of coronary angioscopy.
Journal: Heart (British Cardiac Society) 20071101
Title: Distinctive expression and functional regulation of the maize (Zea mays L.) TOR kinase ortholog.
Journal: Molecular bioSystems 20071101
Title: Impact of the metabolic syndrome on angiographic and clinical events after coronary intervention using bare-metal or sirolimus-eluting stents.
Journal: The American journal of cardiology 20071101
Title: Post-renal transplant hemolytic uremic syndrome following combination therapy with tacrolimus and everolimus.
Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20071101
Title: Successful treatment of post-renal transplant gastric and pulmonary Kaposi's sarcoma with conversion to rapamycin treatment.
Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20071101
Title: TOR signalling regulates mitotic commitment through the stress MAP kinase pathway and the Polo and Cdc2 kinases.
Journal: Nature cell biology 20071101
Title: Coronary artery bypass grafting versus coronary implantation of sirolimus-eluting stents in patients with diabetic retinopathy.
Journal: The Annals of thoracic surgery 20071101
Title: Three-year clinical outcomes after coronary stenting of chronic total occlusion using sirolimus-eluting stents: insights from the rapamycin-eluting stent evaluated at Rotterdam cardiology hospital-(RESEARCH) registry.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071101
Title: Why do DES not alter long-term outcomes? Why would they, after all, it's a chronic disease.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071101
Title: Sirolimus inhibits human pancreatic carcinoma cell proliferation by a mechanism linked to the targeting of mTOR/HIF-1 alpha/VEGF signaling.
Journal: IUBMB life 20071101
Title: Laparoscopic incisional hernia repair after liver transplantation.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20071101
Title: A randomized, phase II trial of two dose levels of temsirolimus (CCI-779) in patients with extensive-stage small-cell lung cancer who have responding or stable disease after induction chemotherapy: a trial of the Eastern Cooperative Oncology Group (E1500).
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20071101
Title: Treatment of restenotic drug-eluting stents: an intravascular ultrasound analysis.
Journal: The Journal of invasive cardiology 20071101
Title: The influence of immuosuppressive therapy on the development of CD4+CD25+ T cells after renal transplantation.
Journal: Transplantation proceedings 20071101
Title: Anticancer effect of sirolimus in renal allograft recipients with de novo malignancies.
Journal: Transplantation proceedings 20071101
Title: Comparison of long-term results of drug-eluting stent and bare metal stent implantation in heart transplant recipients with coronary artery disease.
Journal: Transplantation proceedings 20071101
Title: Bevacizumab and rapamycin inhibit tumor growth in peritoneal model of human ovarian cancer.
Journal: Molecular cancer therapeutics 20071101
Title: Autophagy in cardiovascular disease.
Journal: Trends in molecular medicine 20071101
Title: Cancer after renal transplantation.
Journal: Current opinion in nephrology and hypertension 20071101
Title: Comparison of long-term clinical outcome after sirolimus-eluting stent implantation in patients with and without hemodialysis.
Journal: International heart journal 20071101
Title: Late multiple stent fractures following deployment of sirolimus-eluting stents for diffuse right coronary artery stenosis.
Journal: International heart journal 20071101
Title: Temsirolimus for advanced renal cell carcinoma.
Journal: Clinical advances in hematology & oncology : H&O 20071101
Title: A randomized phase II study of pemetrexed or RAD001 as second-line treatment of advanced non-small-cell lung cancer in elderly patients: treatment rationale and protocol dynamics.
Journal: Clinical lung cancer 20071101
Title: [Clinical features of late stent thrombosis after successful sirolimus-eluting stent implantation].
Journal: Zhonghua xin xue guan bing za zhi 20071101
Title: Sirolimus versus cyclosporine therapy increases circulating regulatory T cells, but does not protect renal transplant patients given alemtuzumab induction from chronic allograft injury.
Journal: Transplantation 20071027
Title: Sirolimus modifies cholesterol homeostasis in hepatic cells: a potential molecular mechanism for sirolimus-associated dyslipidemia.
Journal: Transplantation 20071027
Title: One-year results of the SCORPIUS study: a German multicenter investigation on the effectiveness of sirolimus-eluting stents in diabetic patients.
Journal: Journal of the American College of Cardiology 20071023
Title: Features and parameters of drug-eluting stent deployment discoverable by intravascular ultrasound.
Journal: The American journal of cardiology 20071022
Title: The significance of preclinical evaluation of sirolimus-, paclitaxel-, and zotarolimus-eluting stents.
Journal: The American journal of cardiology 20071022
Title: Zotarolimus-eluting stents in patients with native coronary artery disease: clinical and angiographic outcomes in 1,317 patients.
Journal: The American journal of cardiology 20071022
Title: Four-year clinical follow-up after implantation of the endeavor zotarolimus-eluting stent: ENDEAVOR I, the first-in-human study.
Journal: The American journal of cardiology 20071022
Title: The relation between clinical features, angiographic findings, and the target lesion revascularization rate in patients receiving the endeavor zotarolimus-eluting stent for treatment of native coronary artery disease: an analysis of ENDEAVOR I, ENDEAVOR II, ENDEAVOR II Continued Access Registry, and ENDEAVOR III.
Journal: The American journal of cardiology 20071022
Title: Intravascular ultrasound findings in ENDEAVOR II and ENDEAVOR III.
Journal: The American journal of cardiology 20071022
Title: Real-world safety and efficacy of the endeavor zotarolimus-eluting stent: early data from the E-Five Registry.
Journal: The American journal of cardiology 20071022
Title: Phase I study of everolimus in pediatric patients with refractory solid tumors.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071020
Title: Basal activation of p70S6K results in adipose-specific insulin resistance in protein-tyrosine phosphatase 1B -/- mice.
Journal: The Journal of biological chemistry 20071019
Title: Rapamycin regulates the phosphorylation of rictor.
Journal: Biochemical and biophysical research communications 20071019
Title: Normal phase and reverse phase HPLC-UV-MS analysis of process impurities for rapamycin analog ABT-578: application to active pharmaceutical ingredient process development.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071015
Title: Comparison of outcomes using sirolimus-eluting stenting in diabetic versus nondiabetic patients with comparison of insulin versus non-insulin therapy in the diabetic patients.
Journal: The American journal of cardiology 20071015
Title: Thymic stromal-derived lymphopoietin induces proliferation of pre-B leukemia and antagonizes mTOR inhibitors, suggesting a role for interleukin-7Ralpha signaling.
Journal: Cancer research 20071015
Title: Sirolimus-related pulmonary toxicity mimicking 'asthma like' symptoms.
Journal: World journal of gastroenterology 20071014
Title: Posttransplant Epstein-Barr virus related lymphoproliferative disorder with a primary cutaneous presentation.
Journal: Dermatology online journal 20071013
Title: S6K1-mediated disassembly of mitochondrial URI/PP1gamma complexes activates a negative feedback program that counters S6K1 survival signaling.
Journal: Molecular cell 20071012
Title: [Impact of sirolimus on collagen synthesis in vascular smooth muscle cells: experiment with rat].
Journal: Zhonghua yi xue za zhi 20071009
Title: mTOR is the rapamycin-sensitive kinase that confers mechanically-induced phosphorylation of the hydrophobic motif site Thr(389) in p70(S6k).
Journal: FEBS letters 20071002
Title: Long-term clinical outcomes with sirolimus-eluting coronary stents: five-year results of the RAVEL trial.
Journal: Journal of the American College of Cardiology 20071002
Title: Sirolimus-eluting stent implantation aggravates endothelial vasomotor dysfunction in the infarct-related coronary artery in patients with acute myocardial infarction.
Journal: Journal of the American College of Cardiology 20071002
Title: A meta-analysis of 16 randomized trials of sirolimus-eluting stents versus paclitaxel-eluting stents in patients with coronary artery disease.
Journal: Journal of the American College of Cardiology 20071002
Title: The Emperor's new clothes: another cypher versus taxus post-hoc meta-analysis.
Journal: Journal of the American College of Cardiology 20071002
Title: Reduced systemic inflammatory response to implantation of sirolimus-eluting stents in patients with stable coronary artery disease.
Journal: Atherosclerosis 20071001
Title: PIM-2 is an independent regulator of chondrocyte survival and autophagy in the epiphyseal growth plate.
Journal: Journal of cellular physiology 20071001
Title: Multiple sirolimus eluting stent fractures.
Journal: European heart journal 20071001
Title: Comparison of in vivo acute stent recoil between the bioabsorbable everolimus-eluting coronary stent and the everolimus-eluting cobalt chromium coronary stent: insights from the ABSORB and SPIRIT trials.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001
Title: Late vascular response at the edges of sirolimus analogous-eluting stents in diabetic patients: An intravascular ultrasound study.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001
Title: Comparison of a treatment strategy combining CCI-779 plus DTIC versus DTIC monotreatment in human melanoma in SCID mice.
Journal: The Journal of investigative dermatology 20071001
Title: Steroid and oxygen effects on eIF4F complex, mTOR, and ENaC translation in fetal lung epithelia.
Journal: American journal of respiratory cell and molecular biology 20071001
Title: Determination of sirolimus in rabbit arteries using liquid chromatography separation and tandem mass spectrometric detection.
Journal: Biomedical chromatography : BMC 20071001
Title: Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver.
Journal: Blood 20071001
Title: The application of ink-jet technology for the coating and loading of drug-eluting stents.
Journal: Annals of biomedical engineering 20071001
Title: Translational control of nrf2 protein in activation of antioxidant response by oxidants.
Journal: Molecular pharmacology 20071001
Title: Reversal of portal hypertension and hyperdynamic splanchnic circulation by combined vascular endothelial growth factor and platelet-derived growth factor blockade in rats.
Journal: Hepatology (Baltimore, Md.) 20071001
Title: Initial clinical impact of drug eluting stents on coronary artery bypass graft surgery.
Journal: Interactive cardiovascular and thoracic surgery 20071001
Title: Early experience with conversion to sirolimus in a pediatric renal transplant population.
Journal: Pediatric nephrology (Berlin, Germany) 20071001
Title: Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study.
Journal: American journal of physiology. Lung cellular and molecular physiology 20071001
Title: Methanol-associated matrix effects in electrospray ionization tandem mass spectrometry.
Journal: Clinical chemistry 20071001
Title: Azoospermia in a renal transplant recipient during sirolimus (rapamycin) treatment.
Journal: Andrologia 20071001
Title: Rapamycin: something old, something new, sometimes borrowed and now renewed.
Journal: Clinical pharmacology and therapeutics 20071001
Title: Mammalian target of rapamycin inhibition halts the progression of proteinuria in a rat model of reduced renal mass.
Journal: Journal of the American Society of Nephrology : JASN 20071001
Title: Sirolimus-associated infertility: case report and literature review of possible mechanisms.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071001
Title: Three-year health-related quality-of-life outcomes for sirolimus-treated kidney transplant patients after elimination of cyclosporine.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20071001
Title: The role of mTOR inhibition in augmenting radiation induced autophagy.
Journal: Technology in cancer research & treatment 20071001
Title: Effects of ciclosporin A, tacrolimus and sirolimus on cytokine production in neonatal immune cells.
Journal: Acta paediatrica (Oslo, Norway : 1992) 20071001
Title: Comparison of triple versus dual antiplatelet therapy after drug-eluting stent implantation (from the DECLARE-Long trial).
Journal: The American journal of cardiology 20071001
Title: Rapamycin reduces CCR5 mRNA levels in macaques: potential applications in HIV-1 prevention and treatment.
Journal: AIDS (London, England) 20071001
Title: Sirolimus-eluting stent treatment for unprotected versus protected left main coronary artery disease in widespread clinical routine: 6-month and 3-year clinical follow-up results from the prospective multicentre German Cypher Registry.
Journal: Heart (British Cardiac Society) 20071001
Title: Outcome in the elderly undergoing percutaneous coronary intervention with sirolimus-eluting stents: results from the prospective multicenter German Cypher Stent Registry.
Journal: American heart journal 20071001
Title: Impact of diabetes mellitus on long-term outcomes in the drug-eluting stent era.
Journal: American heart journal 20071001
Title: Impact of drug-eluting stents on clinical and angiographic outcomes in dialysis patients.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20071001
Title: Polymeric stents: degradable but strong.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001
Title: The SIRIUS-DIRECT trial: a multi-center study of direct stenting using the sirolimus-eluting stent in patients with de novo native coronary artery lesions.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001
Title: Direct stenting in the DES era: Can we do better?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001
Title: The pros and cons of living on the edge.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001
Title: Identification of everolimus metabolite patterns in trough blood samples of kidney transplant patients.
Journal: Therapeutic drug monitoring 20071001
Title: Internal standard selection for the high-performance liquid chromatography tandem mass spectroscopy assay of everolimus in blood.
Journal: Therapeutic drug monitoring 20071001
Title: Aging increases pulmonary veins arrhythmogenesis and susceptibility to calcium regulation agents.
Journal: Heart rhythm 20071001
Title: Utility of sirolimus-eluting Cypher stents to reduce 12-month target vessel revascularization in saphenous vein graft stenoses: results of a multicenter 350-patient case-control study.
Journal: The Journal of invasive cardiology 20071001
Title: Spontaneous coronary artery perforation secondary to a sirolimus-eluting stent infection.
Journal: The Journal of invasive cardiology 20071001
Title: Preclinical testing of clinically applicable strategies for overcoming trastuzumab resistance caused by PTEN deficiency.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20071001
Title: Sirolimus-based immunosuppression after cardiac transplantation: predictors of recovery from calcineurin inhibitor-induced renal dysfunction.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20071001
Title: Treatment of unprotected left main coronary artery stenosis in a 5-year-old heart transplant patient using a sirolimus-eluting stent.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20071001
Title: Sirolimus: efficacy in liver transplant patients with nephrotoxicity and renal insufficiency.
Journal: Transplantation proceedings 20071001
Title: Drug-eluting stent implantation results in effective treatment of small coronary artery disease (DESIRE Small CAD).
Journal: Connecticut medicine 20071001
Title: Sirolimus-associated diffuse alveolar hemorrhage in a renal transplant recipient on long-term anticoagulation.
Journal: Clinical nephrology 20071001
Title: Immune responses to gene product of inducible promoters.
Journal: Current gene therapy 20071001
Title: Anti-inflammatory effect of abciximab-coated stent in a porcine coronary restenosis model.
Journal: Journal of Korean medical science 20071001
Title: Temsirolimus.
Journal: Drugs of today (Barcelona, Spain : 1998) 20071001
Title: [Long-term clinical benefits of using active stents in diabetic patients: two year follow-up of a consecutive series of 122 patients].
Journal: Archives des maladies du coeur et des vaisseaux 20071001
Title: Cancer and transplantation intersect at the mammalian target of rapamycin.
Journal: Transplantation 20070927
Title: Use of everolimus as a rescue immunosuppressive therapy in liver transplant patients with neoplasms.
Journal: Transplantation 20070927
Title: Comparative clinical outcomes of paclitaxel- and sirolimus-eluting stents: results from a large prospective multicenter registry--STENT Group.
Journal: Journal of the American College of Cardiology 20070925
Title: Detecting binding interactions using microarrays of natural product extracts.
Journal: Journal of the American Chemical Society 20070919
Title: Impact of vessel size on outcome after implantation of sirolimus-eluting and paclitaxel-eluting stents: a subgroup analysis of the SIRTAX trial.
Journal: Journal of the American College of Cardiology 20070918
Title: Drug-eluting stent update 2007: part III: Technique and unapproved/unsettled indications (left main, bifurcations, chronic total occlusions, small vessels and long lesions, saphenous vein grafts, acute myocardial infarctions, and multivessel disease).
Journal: Circulation 20070918
Title: Low-dose arsenic trioxide sensitizes glucocorticoid-resistant acute lymphoblastic leukemia cells to dexamethasone via an Akt-dependent pathway.
Journal: Blood 20070915
Title: Quantification of cyclosporine A in peripheral blood mononuclear cells by liquid chromatography-electrospray mass spectrometry using a column-switching approach.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070915
Title: Safety of drug-eluting stents in the coronary artery in ST-elevation myocardial infarction at a single high-volume medical center.
Journal: The American journal of cardiology 20070915
Title: Correlates of clinical restenosis following intracoronary implantation of drug-eluting stents.
Journal: The American journal of cardiology 20070915
Title: Drug-eluting stents and late stent thrombosis.
Journal: Lancet (London, England) 20070915
Title: Outcomes associated with drug-eluting and bare-metal stents: a collaborative network meta-analysis.
Journal: Lancet (London, England) 20070915
Title: Targeting human medulloblastoma: oncolytic virotherapy with myxoma virus is enhanced by rapamycin.
Journal: Cancer research 20070915
Title: Expansion of human T regulatory type 1 cells in the microenvironment of cyclooxygenase 2 overexpressing head and neck squamous cell carcinoma.
Journal: Cancer research 20070915
Title: Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation.
Journal: Circulation research 20070914
Title: Interferon-gamma and intimal hyperplasia.
Journal: Circulation research 20070914
Title: D-glucosamine inhibits proliferation of human cancer cells through inhibition of p70S6K.
Journal: Biochemical and biophysical research communications 20070907
Title: RB1CC1 insufficiency causes neuronal atrophy through mTOR signaling alteration and involved in the pathology of Alzheimer's diseases.
Journal: Brain research 20070907
Title: Temsirolimus for advanced renal-cell carcinoma.
Journal: The New England journal of medicine 20070906
Title: Temsirolimus for advanced renal-cell carcinoma.
Journal: The New England journal of medicine 20070906
Title: Coronary stent fracture and restenosis in the drug-eluting stent era: do we have clues of management?
Journal: International journal of cardiology 20070903
Title: Cardiogenic shock caused by simultaneous subacute stent thrombosis after implantation of sirolimus-eluting stents.
Journal: International journal of cardiology 20070903
Title: Comparison of angiographic patterns of in-stent restenosis between sirolimus- and paclitaxel-eluting stent.
Journal: International journal of cardiology 20070903
Title: Understanding the drug-eluting stent trials.
Journal: The American journal of cardiology 20070903
Title: Expansion and characteristics of human T regulatory type 1 cells in co-cultures simulating tumor microenvironment.
Journal: Cancer immunology, immunotherapy : CII 20070901
Title: Specific mTOR inhibitor rapamycin enhances cytotoxicity induced by alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU) in human U251 malignant glioma cells.
Journal: Journal of neuro-oncology 20070901
Title: Telomere 3' overhang-specific DNA oligonucleotides induce autophagy in malignant glioma cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070901
Title: Genetic and pharmacologic evidence implicating the p85 alpha, but not p85 beta, regulatory subunit of PI3K and Rac2 GTPase in regulating oncogenic KIT-induced transformation in acute myeloid leukemia and systemic mastocytosis.
Journal: Blood 20070901
Title: Improved blood compatibility of rapamycin-eluting stent by incorporating curcumin.
Journal: Colloids and surfaces. B, Biointerfaces 20070901
Title: In vitro metabolic study of temsirolimus: preparation, isolation, and identification of the metabolites.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070901
Title: Incidence of anemia in sirolimus-treated renal transplant recipients: the importance of preserving renal function.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20070901
Title: Predictors of long-term outcome following liver transplantation for hepatocellular carcinoma: a single-center experience.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20070901
Title: Reflex sympathetic dystrophy in a renal transplant patient treated with sirolimus.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070901
Title: Golgi manganese transport is required for rapamycin signaling in Saccharomyces cerevisiae.
Journal: Genetics 20070901
Title: Prevention of TGF-beta-induced apoptosis by interlukin-4 through Akt activation and p70S6K survival signaling pathways.
Journal: Apoptosis : an international journal on programmed cell death 20070901
Title: Serotonin induces memory-like, rapamycin-sensitive hyperexcitability in sensory axons of aplysia that contributes to injury responses.
Journal: Journal of neurophysiology 20070901
Title: Treatment options in steroid-refractory acute graft-versus-host disease following hematopoietic stem cell transplantation.
Journal: The Annals of pharmacotherapy 20070901
Title: Use of sirolimus-eluting stents for treatment of in-stent restenosis: long-term follow-up.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20070901
Title: Treatment of restenosis after bare-metal and drug-eluting stenting of an aorto-ostial lesion: challenges associated with excessive stent overhang.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20070901
Title: Noble gases without anesthetic properties protect myocardium against infarction by activating prosurvival signaling kinases and inhibiting mitochondrial permeability transition in vivo.
Journal: Anesthesia and analgesia 20070901
Title: A randomized comparison of sirolimus-eluting stent implantation with zotarolimus-eluting stent implantation for the treatment of total coronary occlusions: rationale and design of the PRImary Stenting of Occluded Native coronary arteries III (PRISON III) study.
Journal: American heart journal 20070901
Title: A comparison of mortality, myocardial infarction, and repeated revascularization for sirolimus-eluting and paclitaxel-eluting coronary stents.
Journal: American heart journal 20070901
Title: Nonrandomized comparison of coronary stenting under intravascular ultrasound guidance of direct stenting without predilation versus conventional predilation with a semi-compliant balloon versus predilation with a new scoring balloon.
Journal: The American journal of cardiology 20070901
Title: Detailed intravascular ultrasound analysis of Zotarolimus-eluting phosphorylcholine-coated cobalt-chromium alloy stent in de novo coronary lesions (results from the ENDEAVOR II trial).
Journal: The American journal of cardiology 20070901
Title: Stent thrombosis after sirolimus- and paclitaxel-eluting stent implantation in daily clinical practice: analysis of a single center registry.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070901
Title: Sirolimus-eluting stent implantation for treatment of proximal left anterior descending coronary artery lesions: long-term outcome and predictors of adverse cardiac events.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070901
Title: Treatment options in renal cell carcinoma: past, present and future.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20070901
Title: Phase I/II trial of temsirolimus combined with interferon alfa for advanced renal cell carcinoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070901
Title: The combination of novel low molecular weight inhibitors of RAF (LBT613) and target of rapamycin (RAD001) decreases glioma proliferation and invasion.
Journal: Molecular cancer therapeutics 20070901
Title: Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle.
Journal: Cell metabolism 20070901
Title: Fatal Epstein-Barr virus-associated lymphoproliferative disorder following treatment with a novel mTOR inhibitor for relapsed chronic lymphocytic leukemia leukemia cells.
Journal: Haematologica 20070901
Title: Prospective assessment of discontinuation and reinitiation of erlotinib or gefitinib in patients with acquired resistance to erlotinib or gefitinib followed by the addition of everolimus.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070901
Title: Outlook of drug-eluting stent implantation for unprotected left main disease: insights on long-term clinical predictors.
Journal: The Journal of invasive cardiology 20070901
Title: Sirolimus-eluting stent thrombosis several years after clopidogrel discontinuation.
Journal: The Journal of invasive cardiology 20070901
Title: Sirolimus monotherapy as maintenance immunosuppression: single-center experience in 50 kidney transplant patients.
Journal: Transplantation proceedings 20070901
Title: mTOR inhibitors: do they help preserve renal function?
Journal: Transplantation proceedings 20070901
Title: Conversion from calcineurin inhibitors to sirolimus in kidney transplant patients reduces the urinary transforming growth factor-beta1 concentration.
Journal: Transplantation proceedings 20070901
Title: Pharmacogenetics of tacrolimus and sirolimus in renal transplant patients: from retrospective analyses to prospective studies.
Journal: Transplantation proceedings 20070901
Title: Evaluation of the efficacy and safety of the conversion from a calcineurin inhibitor to an everolimus-based therapy in maintenance renal transplant patients.
Journal: Transplantation proceedings 20070901
Title: Early sirolimus use with cyclosporine elimination does not induce progressive proteinuria.
Journal: Transplantation proceedings 20070901
Title: Use of the new proliferation signal inhibitor everolimus in renal transplant patients in Spain: preliminary results of the EVERODATA registry.
Journal: Transplantation proceedings 20070901
Title: Study of anemia after late introduction of everolimus in the immunosuppressive treatment of renal transplant patients.
Journal: Transplantation proceedings 20070901
Title: Conversion to sirolimus in posttransplant renal neoplasms.
Journal: Transplantation proceedings 20070901
Title: mTOR inhibitors and their secondary effects in cardiac transplant recipients: a descriptive study.
Journal: Transplantation proceedings 20070901
Title: Impact on renal function of the use of sirolimus in cardiac transplantation.
Journal: Transplantation proceedings 20070901
Title: Sirolimus in renal transplantation.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070901
Title: Sirolimus for visceral and cutaneous Kaposi's sarcoma in a renal-transplant recipient.
Journal: Clinical and experimental nephrology 20070901
Title: New techniques and developments of stenting for infrainguinal arterial occlusive disease: are the results any better than balloon angioplasty alone?
Journal: Perspectives in vascular surgery and endovascular therapy 20070901
Title: [Relationship between plasma C-reactive protein level and neointimal hyperplasia volume in patients with zotarolimus-eluting stents. Volumetric analysis by three-dimensional intracoronary ultrasound].
Journal: Revista espanola de cardiologia 20070901
Title: Sunitinib, sorafenib and mTOR inhibitors in renal cancer.
Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20070901
Title: Etanercept therapy for severe plaque psoriasis in a patient who underwent a liver transplant.
Journal: Cutis 20070901
Title: Metastatic renal cell carcinoma: role of mammalian target of rapamycin inhibitors.
Journal: Clinical genitourinary cancer 20070901
Title: Potential histologic and molecular predictors of response to temsirolimus in patients with advanced renal cell carcinoma.
Journal: Clinical genitourinary cancer 20070901
Title: [3/3 Inhibitors of mTOR (sirolimus and everolimus)].
Journal: Soins; la revue de reference infirmiere 20070901
Title: Drug-eluting stent implantation could be associated with long-term coronary endothelial dysfunction.
Journal: International heart journal 20070901
Title: Very late stent thrombosis in late stent malapposition after sirolimus-eluting stent implantation.
Journal: International heart journal 20070901
Title: Chemical control over protein-protein interactions: beyond inhibitors.
Journal: Combinatorial chemistry & high throughput screening 20070901
Title: siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy.
Journal: The Journal of biological chemistry 20070831
Title: Replacement of calcineurin-inhibitors with sirolimus as primary immunosuppression in stable cardiac transplant recipients.
Journal: Transplantation 20070827
Title: PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex.
Journal: The Journal of biological chemistry 20070824
Title: Off-label use of drug-eluting stents.
Journal: JAMA 20070822
Title: Serial angioscopic evidence of incomplete neointimal coverage after sirolimus-eluting stent implantation: comparison with bare-metal stents.
Journal: Circulation 20070821
Title: An activated mTOR/p70S6K signaling pathway in esophageal squamous cell carcinoma cell lines and inhibition of the pathway by rapamycin and siRNA against mTOR.
Journal: Cancer letters 20070818
Title: Inhibition of mammalian target of rapamycin signaling by 2-(morpholin-1-yl)pyrimido[2,1-alpha]isoquinolin-4-one.
Journal: The Journal of biological chemistry 20070817
Title: Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
Journal: Oncogene 20070816
Title: Intravascular ultrasound parameters associated with stent thrombosis after drug-eluting stent deployment.
Journal: The American journal of cardiology 20070815
Title: Sequential quadruple immunosuppression including sirolimus in extended criteria and nonheartbeating donor kidney transplantation.
Journal: Transplantation 20070815
Title: Incidence and predictors of drug-eluting stent thrombosis during and after discontinuation of thienopyridine treatment.
Journal: Circulation 20070814
Title: Drug-eluting stents: dual antiplatelet therapy for every survivor?
Journal: Circulation 20070814
Title: The effects of mTOR-Akt interactions on anti-apoptotic signaling in vascular endothelial cells.
Journal: The Journal of biological chemistry 20070810
Title: Risk factors for stent thrombosis after implantation of sirolimus-eluting stents in diabetic and nondiabetic patients: the EVASTENT Matched-Cohort Registry.
Journal: Journal of the American College of Cardiology 20070807
Title: [Lymphocele and kidney transplantation].
Journal: Orvosi hetilap 20070805
Title: Structure of TOR and its complex with KOG1.
Journal: Molecular cell 20070803
Title: PI 3-K signaling pathway suppresses PMA-induced expression of p21WAF1/Cip1 in human leukemia cells.
Journal: Molecular and cellular biochemistry 20070801
Title: Snare extraction of a fractured coronary stent in a saphenous vein graft.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070801
Title: Bifurcation stenting with a dedicated biolimus-eluting stent: X-ray visual enhancement of the final angiographic result with 'StentBoost Subtract'.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070801
Title: Late drug-eluting stent thrombosis and erythropoietin: cause and effect?
Journal: Heart, lung & circulation 20070801
Title: Sirolimus and paclitaxel provoke different vascular pathological responses after local delivery in a murine model for restenosis on underlying atherosclerotic arteries.
Journal: Heart (British Cardiac Society) 20070801
Title: Influence of sirolimus on proteinuria in de novo kidney transplantation with expanded criteria donors: comparison of two CNI-free protocols.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070801
Title: S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover.
Journal: American journal of physiology. Cell physiology 20070801
Title: Mammalian target of rapamycin: master regulator of cell growth in the nervous system.
Journal: Histology and histopathology 20070801
Title: Comparison between sirolimus- and paclitaxel-eluting stents in complex patient and lesions subsets.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070801
Title: The Sirolimus-eluting coronary stent in daily routine practice in Germany: trends in indications over the years. Results from the prospective multi-centre German Cypher Stent Registry.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20070801
Title: Myocardial ischaemia-reperfusion injury is attenuated by intact glucagon like peptide-1 (GLP-1) in the in vitro rat heart and may involve the p70s6K pathway.
Journal: Cardiovascular drugs and therapy 20070801
Title: Late-phase, protein synthesis-dependent long-term potentiation in hippocampal CA1 pyramidal neurones with destabilized microtubule networks.
Journal: British journal of pharmacology 20070801
Title: Renoprotective effects of sirolimus in non-immune initiated focal segmental glomerulosclerosis.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070801
Title: Combination of the oncolytic adenovirus ICOVIR-5 with chemotherapy provides enhanced anti-glioma effect in vivo.
Journal: Cancer gene therapy 20070801
Title: Long-term clinical benefit of sirolimus-eluting stent implantation in diabetic patients with de novo coronary stenoses: long-term results of the DIABETES trial.
Journal: European heart journal 20070801
Title: Phase 1 trial of everolimus and gefitinib in patients with advanced nonsmall-cell lung cancer.
Journal: Cancer 20070801
Title: The effect of sirolimus therapy on vaccine responses in transplant recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070801
Title: Increased iNOS-expressing macrophage in long-term surviving rat small-bowel grafts.
Journal: American journal of surgery 20070801
Title: Three-year follow-up of the first prospective randomized comparison between paclitaxel and sirolimus stents: the TAXi-LATE trial.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070801
Title: What kind of stent for you today and how would you like it prepared?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070801
Title: Tuberous sclerosis complex: advances in diagnosis, genetics, and management.
Journal: Journal of the American Academy of Dermatology 20070801
Title: Vascular pathology as a result of drug-eluting stents.
Journal: Heart (British Cardiac Society) 20070801
Title: Parallel stenting using two sirolimus-eluting stents in an ectatic coronary artery stenosis.
Journal: Heart (British Cardiac Society) 20070801
Title: Shared signaling networks active in B cells isolated from genetically distinct mouse models of lupus.
Journal: The Journal of clinical investigation 20070801
Title: Culotte versus T-stenting in bifurcation lesions: immediate clinical and angiographic results and midterm clinical follow-up.
Journal: American heart journal 20070801
Title: Neointimal progression and luminal narrowing in sirolimus-eluting stent treatment for bare metal in-stent restenosis: a quantitative intravascular ultrasound analysis.
Journal: American heart journal 20070801
Title: Drug-eluting stents vs bare metal stents for the treatment of large coronary vessels.
Journal: American heart journal 20070801
Title: External application of rapamycin-eluting film at anastomotic sites inhibits neointimal hyperplasia in a canine model.
Journal: The Annals of thoracic surgery 20070801
Title: Modulation of cholesterol homeostasis by antiproliferative drugs in human pterygium fibroblasts.
Journal: Investigative ophthalmology & visual science 20070801
Title: Predictors of target lesion revascularization and documented stent thrombosis beyond 30 days after sirolimus-eluting stent implantation: retrospective analysis in consecutive 1,070 angiographic follow-up lesions.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20070801
Title: Comparison of six-month angiographic and three-year outcomes after sirolimus-eluting stent implantation versus brachytherapy for bare metal in-stent restenosis.
Journal: The American journal of cardiology 20070801
Title: Long-term clinical and angiographic outcomes of treatment of unprotected left main coronary artery stenosis with sirolimus-eluting stents.
Journal: The American journal of cardiology 20070801
Title: Monitoring biological action of rapamycin in renal transplantation.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20070801
Title: Analysis of programmed cell death in mouse fetal oocytes.
Journal: Reproduction (Cambridge, England) 20070801
Title: Direct stenting limits sirolimus-eluting stent edge neointimal thickening.
Journal: Journal of vascular surgery 20070801
Title: American Society of Clinical Oncology--43rd annual meeting. Translating research into practice.
Journal: IDrugs : the investigational drugs journal 20070801
Title: Rationale for a phase I trial of erlotinib and the mammalian target of rapamycin inhibitor everolimus (RAD001) for patients with relapsed non small cell lung cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070801
Title: An improved bioluminescence resonance energy transfer strategy for imaging intracellular events in single cells and living subjects.
Journal: Cancer research 20070801
Title: [The relationship of mTOR signaling pathway and histone acetylation in human gastric cancer cell lines].
Journal: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20070801
Title: Sirolimus as primary immunosuppressant for calcineurin inhibitor-related renal insufficiency after liver transplantation.
Journal: Hepatobiliary & pancreatic diseases international : HBPD INT 20070801
Title: mTOR in tuberous sclerosis and other neurological disorders.
Journal: Epilepsia 20070801
Title: Akt-induced endocrine therapy resistance is reversed by inhibition of mTOR signaling.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20070801
Title: Sirolimus-eluting versus bare-metal low-profile stent for renal artery treatment (GREAT Trial): angiographic follow-up after 6 months and clinical outcome up to 2 years.
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20070801
Title: Rapamycin inhibits multiple stages of c-Neu/ErbB2 induced tumor progression in a transgenic mouse model of HER2-positive breast cancer.
Journal: Molecular cancer therapeutics 20070801
Title: Usefulness of drug eluting stent in percutaneous coronary intervention--a single center experience in Taiwan.
Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20070801
Title: Short- and long-term clinical outcomes of coronary drug-eluting stent recipients presenting with chronic renal disease.
Journal: The Journal of invasive cardiology 20070801
Title: Phase I trial of sirolimus combined with radiation and cisplatin in non-small cell lung cancer.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20070801
Title: The biology behind mTOR inhibition in sarcoma.
Journal: The oncologist 20070801
Title: [Frequency and characteristics of incomplete stent apposition during and after sirolimus-eluting stent implantation].
Journal: Journal of cardiology 20070801
Title: Economic analysis of the use of drug-eluting stents from the perspective of Belgian health care.
Journal: Acta cardiologica 20070801
Title: [Comparison of effects between China made sirolimus-eluting stents and bare stents for treating patients with acute myocardial infarction].
Journal: Zhonghua xin xue guan bing za zhi 20070801
Title: Drug eluting stents: focus on Cypher sirolimus-eluting coronary stents in the treatment of patients with bifurcation lesions.
Journal: Vascular health and risk management 20070801
Title: Update on stents: recent studies on the TAXUS stent system in small vessels.
Journal: Vascular health and risk management 20070801
Title: Mechanisms of mammalian target of rapamycin inhibition in sarcoma: present and future.
Journal: Expert review of anticancer therapy 20070801
Title: Release profiles in drug-eluting stents: issues and uncertainties.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20070731
Title: Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy.
Journal: FEBS letters 20070724
Title: Increased late mortality after sirolimus-eluting stents versus bare-metal stents in diseased saphenous vein grafts: results from the randomized DELAYED RRISC Trial.
Journal: Journal of the American College of Cardiology 20070717
Title: 'Crying fire in a theater' or a 'confirmatory sighting?'.
Journal: Journal of the American College of Cardiology 20070717
Title: Sirolimus-based graft-versus-host disease prophylaxis protects against cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation: a cohort analysis.
Journal: Blood 20070715
Title: BK virus-associated nephropathy in sirolimus-treated renal transplant patients: incidence, course, and clinical outcomes.
Journal: Transplantation 20070715
Title: RAD001 inhibits human ovarian cancer cell proliferation, enhances cisplatin-induced apoptosis, and prolongs survival in an ovarian cancer model.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070715
Title: Hypoxia-inducible factor 1alpha is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif.
Journal: The Journal of biological chemistry 20070713
Title: Subacute stent thrombosis happening at discharge.
Journal: International journal of cardiology 20070710
Title: Two-year clinical follow-up after sirolimus-eluting versus bare-metal stent implantation assisted by systematic glycoprotein IIb/IIIa Inhibitor Infusion in patients with myocardial infarction: results from the STRATEGY study.
Journal: Journal of the American College of Cardiology 20070710
Title: Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent?
Journal: Sao Paulo medical journal = Revista paulista de medicina 20070705
Title: Differential effects of the immunosuppressive agents cyclosporin A, tacrolimus and sirolimus on drug transport by multidrug resistance proteins.
Journal: Cancer chemotherapy and pharmacology 20070701
Title: Clinical impact of in-stent late loss after drug-eluting coronary stent implantation.
Journal: European heart journal 20070701
Title: Rapamycin together with herceptin significantly increased anti-tumor efficacy compared to either alone in ErbB2 over expressing breast cancer cells.
Journal: International journal of cancer 20070701
Title: Rapamycin retards growth and causes marked alterations in the growth plate of young rats.
Journal: Pediatric nephrology (Berlin, Germany) 20070701
Title: Isolated left pulmonary artery: interventional stenting of a persistent fifth aortic arch.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701
Title: Insulin potentiates Ca2+ signaling and phosphatidylinositol 4,5-bisphosphate hydrolysis induced by Gq protein-coupled receptor agonists through an mTOR-dependent pathway.
Journal: Endocrinology 20070701
Title: Rapamycin blunts nutrient stimulation of eIF4G, but not PKCepsilon phosphorylation, in skeletal muscle.
Journal: American journal of physiology. Endocrinology and metabolism 20070701
Title: Rapamycin prevents thyroid hormone-induced cardiac hypertrophy.
Journal: Endocrinology 20070701
Title: The effect of sirolimus- or cyclosporine-based immunosuppression effects on T-cell subsets in vivo.
Journal: Kidney international 20070701
Title: The acute phase protein alpha2-macroglobulin induces rat ventricular cardiomyocyte hypertrophy via ERK1,2 and PI3-kinase/Akt pathways.
Journal: Cardiovascular research 20070701
Title: Subclinical rejection and sirolimus associated edema in renal allograft recipients.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20070701
Title: Transient sirolimus serum levels after implantation of a sirolimus eluting stent in an infant.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20070701
Title: Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted fetal growth.
Journal: The Journal of physiology 20070701
Title: Vascular endothelial growth factor as a survival factor for human islets: effect of immunosuppressive drugs.
Journal: Diabetologia 20070701
Title: Removal of FKBP12/12.6 from endothelial ryanodine receptors leads to an intracellular calcium leak and endothelial dysfunction.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20070701
Title: Rapamycin reduces CCR5 density levels on CD4 T cells, and this effect results in potentiation of enfuvirtide (T-20) against R5 strains of human immunodeficiency virus type 1 in vitro.
Journal: Antimicrobial agents and chemotherapy 20070701
Title: Vascular responses to drug eluting stents: importance of delayed healing.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20070701
Title: Contrasting effects of cyclosporine and rapamycin in de novo generation of alloantigen-specific regulatory T cells.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070701
Title: Inhibition of endogenous MHC class II-restricted antigen presentation by tacrolimus (FK506) via FKBP51.
Journal: European journal of immunology 20070701
Title: The localization of nuclear exporters of the importin-beta family is regulated by Snf1 kinase, nutrient supply and stress.
Journal: Biochimica et biophysica acta 20070701
Title: Treatment of patients with advanced soft tissue sarcoma: disappointment or challenge?
Journal: Current opinion in oncology 20070701
Title: Insulin-like growth factor-I has different effects on myogenin induction and cell cycle progression in human alveolar and embryonal rhabdomyosarcoma cells.
Journal: International journal of oncology 20070701
Title: Molecular impacts of rapamycin-based drug combinations: combining rapamycin with gemcitabine or imatinib mesylate (Gleevec) in a human leiomyosarcoma model.
Journal: International journal of oncology 20070701
Title: Possible involvement of persistent activity of the mammalian target of rapamycin pathway in the cisplatin resistance of AFP-producing gastric cancer cells.
Journal: Cancer biology & therapy 20070701
Title: Confined late stent thrombosis following clopidogrel withdrawal in a patient with multi-segment sirolimus-eluting stent implants.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20070701
Title: Tumour-derived fibroblast growth factor-2 exerts lymphangiogenic effects through Akt/mTOR/p70S6kinase pathway in rat lymphatic endothelial cells.
Journal: European journal of cancer (Oxford, England : 1990) 20070701
Title: One pathway, many products.
Journal: Nature chemical biology 20070701
Title: Risk of stent thrombosis after sirolimus or paclitaxel eluting coronary stent implantation.
Journal: British journal of clinical pharmacology 20070701
Title: Revascularization for ischemic LV dysfunction: stents or surgery?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701
Title: Comparison of drug-eluting stents with bare metal stents in unselected patients with acute myocardial infarction.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701
Title: Treatment of drug-eluting stent restenosis with the same versus different drug-eluting stent.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701
Title: Two-by-two factorial comparison of high-bolus-dose tirofiban followed by standard infusion versus abciximab and sirolimus-eluting versus bare-metal stent implantation in patients with acute myocardial infarction: design and rationale for the MULTI-STRATEGY trial.
Journal: American heart journal 20070701
Title: Sirolimus-eluting stents compared with standard stents in the treatment of patients with primary angioplasty.
Journal: American heart journal 20070701
Title: Revascularization in severe left ventricular dysfunction: outcome comparison of drug-eluting stent implantation versus coronary artery by-pass grafting.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701
Title: Modified T-stenting with intentional protrusion of the side-branch stent within the main vessel stent to ensure ostial coverage and facilitate final kissing balloon: the T-stenting and small protrusion technique (TAP-stenting). Report of bench testing and first clinical Italian-Korean two-centre experience.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701
Title: The role of mTOR inhibitors for treatment of sarcomas.
Journal: Current oncology reports 20070701
Title: Uneventful thoracic healing with everolimus after aortic valve replacement.
Journal: The Annals of thoracic surgery 20070701
Title: Therapeutics of vein graft intimal hyperplasia: 100 years on.
Journal: The Annals of thoracic surgery 20070701
Title: Duration of clopidogrel therapy after placement of drug-eluting intracoronary stent.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070701
Title: Late restenosis following sirolimus-eluting stent implantation.
Journal: The American journal of cardiology 20070701
Title: Long-term clinical outcomes and thrombosis rates of sirolimus-eluting versus paclitaxel-eluting stents in an unselected population with coronary artery disease (REWARDS registry).
Journal: The American journal of cardiology 20070701
Title: Intravascular ultrasound comparison of sirolimus-eluting stent versus bare metal stent implantation in diseased saphenous vein grafts (from the RRISC [Reduction of Restenosis In Saphenous Vein Grafts With Cypher Sirolimus-Eluting Stent] trial).
Journal: The American journal of cardiology 20070701
Title: Combined therapeutic effects of vinblastine and rapamycin on human neuroblastoma growth, apoptosis, and angiogenesis.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070701
Title: Interleukin-17 and airway inflammation: a longitudinal airway biopsy study after lung transplantation.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070701
Title: Observational study with everolimus (Certican) in combination with low-dose cyclosporine in de novo heart transplant recipients.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070701
Title: Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy.
Journal: Cancer cell 20070701
Title: Angiographic and histological assessment of successfully treated late acute stent thrombosis secondary to a sirolimus-eluting stent.
Journal: European heart journal 20070701
Title: Sensitizing HER2-overexpressing cancer cells to luteolin-induced apoptosis through suppressing p21(WAF1/CIP1) expression with rapamycin.
Journal: Molecular cancer therapeutics 20070701
Title: The influence of low (81 mg) versus high (325 mg) doses of ASA on the incidence of sirolimus-eluting stent thrombosis.
Journal: The Journal of invasive cardiology 20070701
Title: A three-dimensional intravascular ultrasound comparison between the new zotarolimus-eluting stent (ZoMaxx) and the non-drug-eluting TriMaxx stent.
Journal: The Journal of invasive cardiology 20070701
Title: Temsirolimus in the treatment of advanced renal cell carcinoma.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20070701
Title: Sirolimus toxicity and vascular endothelial growth factor release from islet and renal cell lines.
Journal: Transplantation 20070627
Title: Long-term safety and efficacy of drug-eluting stents: two-year results of the REAL (REgistro AngiopLastiche dell'Emilia Romagna) multicenter registry.
Journal: Circulation 20070626
Title: Stress-responsive Gln3 localization in Saccharomyces cerevisiae is separable from and can overwhelm nitrogen source regulation.
Journal: The Journal of biological chemistry 20070622
Title: [Present circumstance around percutaneous coronary intervention (PCI): before and after drug eluting stent (DES) introduction].
Journal: Nihon Hoshasen Gijutsu Gakkai zasshi 20070620
Title: Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis.
Journal: Journal of the American College of Cardiology 20070619
Title: Comparable clinical outcomes with paclitaxel- and sirolimus-eluting stents in unrestricted contemporary practice.
Journal: Journal of the American College of Cardiology 20070619
Title: Phosphorylation of ribosomal p70 S6 kinase and rapamycin sensitivity in human colorectal cancer.
Journal: Cancer letters 20070618
Title: Bystin in human cancer cells: intracellular localization and function in ribosome biogenesis.
Journal: The Biochemical journal 20070615
Title: Six-month clinical and angiographic results of a dedicated drug-eluting stent for the treatment of coronary bifurcation narrowings.
Journal: The American journal of cardiology 20070615
Title: The effects of granulocyte-colony stimulating factor in bare stent and sirolimus-eluting stent in pigs following myocardial infarction.
Journal: International journal of cardiology 20070612
Title: Drug eluting stent implantation for the treatment of symptomatic myocardial bridging is associated with favorable peri-procedural results and short-term outcomes.
Journal: International journal of cardiology 20070612
Title: Sch9 is a major target of TORC1 in Saccharomyces cerevisiae.
Journal: Molecular cell 20070608
Title: Sirolimus-induced posterior reversible encephalopathy.
Journal: Neurology 20070605
Title: Coronary artery stent fracture.
Journal: The international journal of cardiovascular imaging 20070601
Title: Stent fracture: an unusual cause of late restenosis after sirolimus-eluting stent placement.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070601
Title: Target lesion revascularisation in patients treated with a sirolimus-eluting or paclitaxel-eluting stent.
Journal: Heart (British Cardiac Society) 20070601
Title: The rapid activation of protein synthesis by growth hormone requires signaling through mTOR.
Journal: American journal of physiology. Endocrinology and metabolism 20070601
Title: Long-term outcomes of bifurcation lesions after implantation of drug-eluting stents with the 'mini-crush technique'.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070601
Title: Identification and characterization of a functional Candida albicans homolog of the Saccharomyces cerevisiae TCO89 gene.
Journal: FEMS yeast research 20070601
Title: Anti-atherosclerotic effects of sirolimus on human vascular smooth muscle cells.
Journal: American journal of physiology. Heart and circulatory physiology 20070601
Title: The Mammalian target of rapamycin pathway regulates nutrient-sensitive glucose uptake in man.
Journal: Diabetes 20070601
Title: Caerulein-induced intracellular pancreatic zymogen activation is dependent on calcineurin.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070601
Title: Rapamycin-induced hypokalaemic nephropathy in a middle-aged hypertensive male.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070601
Title: Late experimental amebic liver abscess in hamster is inhibited by cyclosporine and N-acetylcysteine.
Journal: Experimental and molecular pathology 20070601
Title: An antibody delivery system for regulated expression of therapeutic levels of monoclonal antibodies in vivo.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20070601
Title: Rapamycin stimulates arginine influx through CAT2 transporters in human endothelial cells.
Journal: Biochimica et biophysica acta 20070601
Title: Comparison of the CEDIA and MEIA assays for the measurement of sirolimus in organ transplant recipients.
Journal: Clinical biochemistry 20070601
Title: Physiologically based pharmacokinetic (PBPK) modeling of everolimus (RAD001) in rats involving non-linear tissue uptake.
Journal: Journal of pharmacokinetics and pharmacodynamics 20070601
Title: The influence of cyclosporin A on lymphocyte attenuator expression.
Journal: Journal of autoimmunity 20070601
Title: mTOR-inhibitors simultaneously inhibit proliferation and basal IL-6 synthesis of human coronary artery endothelial cells.
Journal: International immunopharmacology 20070601
Title: Late incomplete apposition after drug-eluting stent implantation: incidence and potential for adverse clinical outcomes.
Journal: European heart journal 20070601
Title: Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.
Journal: Nature chemical biology 20070601
Title: Is there delayed restenosis in patients with coronary artery disease treated with sirolimus-eluting stent?
Journal: Coronary artery disease 20070601
Title: Severe intimal hyperplasia after sirolimus eluting stent deployment: evaluation by optical coherence tomography.
Journal: Heart (British Cardiac Society) 20070601
Title: Stimulating the cell's appetite for itself.
Journal: Nature chemical biology 20070601
Title: Assessment and validation of the MS/MS fragmentation patterns of the macrolide immunosuppressant everolimus.
Journal: Journal of mass spectrometry : JMS 20070601
Title: Antigenic disparity impacts outcome of agonism but not blockade of costimulatory pathways in experimental transplant models.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070601
Title: Early withdrawal of calcineurin inhibitors and rescue immunosuppression with sirolimus-based therapy in renal transplant recipients with moderate to severe renal dysfunction.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070601
Title: Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20070601
Title: Compared effect of immunosuppressive drugs cyclosporine A and rapamycin on cholesterol homeostasis key enzymes CYP27A1 and HMG-CoA reductase.
Journal: Basic & clinical pharmacology & toxicology 20070601
Title: Stent fracture-unusual cause of DES restenosis.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070601
Title: Sirolimus as part of immunosuppressive therapy for refractory chronic graft-versus-host disease.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20070601
Title: Sirolimus-induced pneumonitis following liver transplantation.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20070601
Title: Subclavian-vertebral artery bifurcation stenting using drug-eluting stents: a report of two cases using different techniques.
Journal: The Journal of invasive cardiology 20070601
Title: Prevention of acute rejection and allograft vasculopathy by everolimus in cardiac transplants recipients: a 24-month analysis.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070601
Title: Low-dose tacrolimus/sirolimus and steroid withdrawal in heart recipients is highly efficacious.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070601
Title: Sirolimus-induced alveolar hemorrhage.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070601
Title: Possible everolimus-induced, severe, reversible encephalopathy after cardiac transplantation.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070601
Title: Endothelial Akt signaling is rate-limiting for rapamycin inhibition of mouse mammary tumor progression.
Journal: Cancer research 20070601
Title: Comparative characterization of cellular and molecular anti-restenotic profiles of paclitaxel and sirolimus. Implications for local drug delivery.
Journal: Thrombosis and haemostasis 20070601
Title: Sirolimus and liver transplantation: clinical implications for hepatocellular carcinoma.
Journal: Expert opinion on pharmacotherapy 20070601
Title: Is sirolimus a nephrotoxic drug? A report of five cases.
Journal: Transplantation proceedings 20070601
Title: Protective effects of sirolimus by attenuating connective tissue growth factor expression in human chronic allograft nephropathy.
Journal: Transplantation proceedings 20070601
Title: Lack of hepatotoxicity upon sirolimus addition to a calcineurin inhibitor-based regimen in hepatitis virus-positive renal transplant recipients.
Journal: Transplantation proceedings 20070601
Title: Rejection episodes and 3-year graft survival under sirolimus and tacrolimus treatment after adult intestinal transplantation.
Journal: Transplantation proceedings 20070601
Title: Comparison of stent graft, sirolimus stent, and bare metal stent implanted in patients with acute coronary syndrome: clinical and angiographic follow-up.
Journal: Croatian medical journal 20070601
Title: Formulation of sirolimus eye drops and corneal permeation studies.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20070601
Title: Progressive multifocal leukoencephalopathy: a case study.
Journal: Progress in transplantation (Aliso Viejo, Calif.) 20070601
Title: Use and long-term outcome of bare metal stent implantation in the drug-eluting stent era.
Journal: Journal of cardiology 20070601
Title: Impact of highly asymmetric stent expansion after sirolimus-eluting stent implantation on twelve-month clinical outcomes.
Journal: Journal of cardiology 20070601
Title: [Limitation on efficacy of sirolimus-eluting stent implantation in patients on hemodialysis].
Journal: Journal of cardiology 20070601
Title: Restenosis developing over one year after implantation with a sirolimus-eluting stent: two case reports.
Journal: Journal of cardiology 20070601
Title: Rational use of drug-eluting stents: a comparison of different policies.
Journal: Critical pathways in cardiology 20070601
Title: [Pilot study of a cell membrane like biomimetic drug-eluting coronary stent].
Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20070601
Title: Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma.
Journal: The New England journal of medicine 20070531
Title: Long-term renal transplant function in recipient of simultaneous kidney and pancreas transplant maintained with two prednisone-free maintenance immunosuppressive combinations: tacrolimus/mycophenolate mofetil versus tacrolimus/sirolimus.
Journal: Transplantation 20070527
Title: Sirolimus conversion in liver transplant recipients with renal dysfunction: a prospective, randomized, single-center trial.
Journal: Transplantation 20070527
Title: Firebird sirolimus eluting stent versus bare mental stent in patients with ST-segment elevation myocardial infarction.
Journal: Chinese medical journal 20070520
Title: Sirolimus eluting stent fracture following angioplasty of diffuse in-stent restenosis in the right coronary artery.
Journal: International journal of cardiology 20070516
Title: Complete fracture of sirolimus-eluting stent detected by multislice computed tomography.
Journal: International journal of cardiology 20070516
Title: Overlapping hybrid stenting with a sirolimus-eluting stent and a bare metal stent.
Journal: International journal of cardiology 20070516
Title: Engineering small molecule specificity in nearly identical cellular environments.
Journal: Bioorganic & medicinal chemistry letters 20070515
Title: Meta-analysis of randomized trials of drug-eluting stents versus bare metal stents in patients with diabetes mellitus.
Journal: The American journal of cardiology 20070515
Title: Percutaneous coronary revascularization using a trilayer metal phosphorylcholine-coated zotarolimus-eluting stent.
Journal: The American journal of cardiology 20070515
Title: De novo sirolimus-based immunosuppression after liver transplantation for hepatocellular carcinoma: long-term outcomes and side effects.
Journal: Transplantation 20070515
Title: CD154 blockade, sirolimus, and donor-specific transfusion prevents renal allograft rejection in cynomolgus monkeys despite homeostatic T-cell activation.
Journal: Transplantation 20070515
Title: Late introduction of sirolimus induces anemia in renal transplant recipients.
Journal: Transplantation 20070515
Title: Randomized trial of Sirolimus-Eluting Stent Versus Bare-Metal Stent in Acute Myocardial Infarction (SESAMI).
Journal: Journal of the American College of Cardiology 20070515
Title: Drug-eluting stents for acute myocardial infarction.
Journal: Journal of the American College of Cardiology 20070515
Title: Outcomes and complications associated with off-label and untested use of drug-eluting stents.
Journal: JAMA 20070509
Title: Clinical outcomes and stent thrombosis following off-label use of drug-eluting stents.
Journal: JAMA 20070509
Title: The enigma of drug-eluting stents: hope, hype, humility, and advancing patient care.
Journal: JAMA 20070509
Title: Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization.
Journal: Circulation 20070508
Title: What to do about late incomplete stent apposition?
Journal: Circulation 20070508
Title: Incomplete stent apposition and very late stent thrombosis after drug-eluting stent implantation.
Journal: Circulation 20070508
Title: The rapamycin-binding domain of the protein kinase mammalian target of rapamycin is a destabilizing domain.
Journal: The Journal of biological chemistry 20070504
Title: CYPHER versus TAXUS stent for bifurcation lesions beyond 30 days-long-term follow-up results.
Journal: International journal of cardiology 20070502
Title: Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells.
Journal: Leukemia research 20070501
Title: Calcineurin-independent inhibition of KV1.3 by FK-506 (tacrolimus): a novel pharmacological property.
Journal: American journal of physiology. Cell physiology 20070501
Title: Impact of renal insufficiency on clinical and angiographic outcomes following percutaneous coronary intervention with sirolimus-eluting stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070501
Title: Factors predictive of cardiac events and restenosis after sirolimus-eluting stent implantation in small coronary arteries.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070501
Title: Diagnosis of de novo localized thrombotic microangiopathy by surveillance biopsy.
Journal: Pediatric nephrology (Berlin, Germany) 20070501
Title: Simultaneous LC-MS-MS determination of cyclosporine A, tacrolimus, and sirolimus in whole blood as well as mycophenolic acid in plasma using common pretreatment procedure.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501
Title: Rapamycin-regulated control of antiangiogenic tumor therapy following rAAV-mediated gene transfer.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20070501
Title: Kidney function after islet transplant alone in type 1 diabetes: impact of immunosuppressive therapy on progression of diabetic nephropathy.
Journal: Diabetes care 20070501
Title: Randomized comparative trial of a thin-strut bare metal cobalt-chromium stent versus a sirolimus-eluting stent for coronary revascularization.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070501
Title: Sirolimus-eluting biodegradable poly-L-lactide stent for peripheral vascular application: a preliminary study in porcine carotid arteries.
Journal: The Journal of surgical research 20070501
Title: Comparison of fluorescent polarization immunoassay (FPIA) versus HPLC to measure everolimus blood concentrations in clinical transplantation.
Journal: Clinica chimica acta; international journal of clinical chemistry 20070501
Title: Vascular remodeling and antitumoral effects of mTOR inhibition in a rat model of hepatocellular carcinoma.
Journal: Journal of hepatology 20070501
Title: Incidence and predictors of target vessel revascularization after sirolimus-eluting stent treatment for proximal left anterior descending artery stenoses among 2274 patients from the prospective multicenter German Cypher Stent Registry.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20070501
Title: Rapamycin, not cyclosporine, permits thymic generation and peripheral preservation of CD4+ CD25+ FoxP3+ T cells.
Journal: Bone marrow transplantation 20070501
Title: The role of proliferation signal inhibitors in post-transplant malignancies.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501
Title: Restenosis following thin-strut bare-metal stents versus thick-strut drug-eluting stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070501
Title: Posterior reversible encephalopathy syndrome due to sirolimus.
Journal: Bone marrow transplantation 20070501
Title: Sirolimus impairs wound healing.
Journal: Langenbeck's archives of surgery 20070501
Title: Stent thrombosis with drug-eluting stents: a re-examination of the evidence.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070501
Title: An in vitro cytologic assay for evaluation of the KIT signaling pathway in gastrointestinal stromal tumors.
Journal: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20070501
Title: Rapamycin, a specific inhibitor of the mammalian target of rapamycin, suppresses lymphangiogenesis and lymphatic metastasis.
Journal: Cancer science 20070501
Title: Influence of the UGT2B7 promoter region and exon 2 polymorphisms and comedications on Acyl-MPAG production in vitro and in adult renal transplant patients.
Journal: Pharmacogenetics and genomics 20070501
Title: Reversal of loss of glomerular filtration rate in children with transplant nephropathy after switch to everolimus and low-dose cyclosporine A.
Journal: Pediatric transplantation 20070501
Title: Reversal of tacrolimus-related hypertrophic cardiomyopathy after conversion to rapamycin in a pediatric liver transplant recipient.
Journal: Pediatric transplantation 20070501
Title: Sirolimus is not always responsible for new-onset proteinuria after conversion for chronic allograft nephropathy.
Journal: Pediatric transplantation 20070501
Title: Therapeutic effect of a new immunosuppressive agent, everolimus, on interleukin-10 gene-deficient mice with colitis.
Journal: Clinical and experimental immunology 20070501
Title: Calcineurin inhibitors and rapamycin: cancer protection or promotion?
Journal: Experimental dermatology 20070501
Title: mTOR as a potential therapeutic target for treatment of keloids and excessive scars.
Journal: Experimental dermatology 20070501
Title: Meta-analysis of clinical trials on use of drug-eluting stents for treatment of acute myocardial infarction.
Journal: American heart journal 20070501
Title: Pretransplant HLA antibodies are associated with reduced graft survival after clinical islet transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070501
Title: Kaposi's sarcoma in renal transplant recipients--the impact of proliferation signal inhibitors.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501
Title: Use of proliferation signal inhibitors in non-melanoma skin cancer following renal transplantation.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501
Title: Post-transplant lymphoproliferative disorder--the potential of proliferation signal inhibitors.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501
Title: Use of proliferation signal inhibitors in the management of post-transplant malignancies--clinical guidance.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501
Title: Conversion to sirolimus-based immunosuppression in maintenance liver transplantation patients.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20070501
Title: Costimulation blockade--what will the future bring?
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501
Title: Do the results of the new trials change the standard treatment of metastatic renal cell cancer?
Journal: Onkologie 20070501
Title: Sirolimus treatment for pulmonary lymphangioleiomyomatosis.
Journal: Annals of internal medicine 20070501
Title: Uncertainty.
Journal: Nature clinical practice. Gastroenterology & hepatology 20070501
Title: Impact of the Food and Drug Administration's Public Health Notification on the adoption of drug-eluting stents.
Journal: The American journal of cardiology 20070501
Title: The Akt/mammalian target of rapamycin signal transduction pathway is activated in high-risk myelodysplastic syndromes and influences cell survival and proliferation.
Journal: Cancer research 20070501
Title: Mammalian target of rapamycin activation impairs hepatocytic differentiation and targets genes moderating lipid homeostasis and hepatocellular growth.
Journal: Cancer research 20070501
Title: Targeted therapies for soft-tissue sarcomas.
Journal: Expert review of anticancer therapy 20070501
Title: A pharmacokinetic interaction between clarithromycin and sirolimus in kidney transplant recipient.
Journal: Current drug metabolism 20070501
Title: Effect of rapamycin on wound healing: an experimental study.
Journal: Transplantation proceedings 20070501
Title: An assay for the determination of sirolimus levels in the lymphocyte of transplant patients.
Journal: Transplantation proceedings 20070501
Title: Lymphedema: an unusual complication of sirolimus therapy.
Journal: Transplantation proceedings 20070501
Title: Optimization of immunosuppressive drug monitoring in children.
Journal: Transplantation proceedings 20070501
Title: Complete regression of cutaneous B-cell lymphoma in a renal transplant patient after conversion from cyclosporin to sirolimus.
Journal: Transplantation proceedings 20070501
Title: Retinal injury as an early manifestation of posttransplant thrombotic microangiopathy: recovery with plasma exchanges and conversion to sirolimus--case report and review of the literature.
Journal: Transplantation proceedings 20070501
Title: Stent fracture and restenosis after placement of a drug-eluting device in the vertebral artery origin and treatment with the stent-in-stent technique. Report of two cases.
Journal: Journal of neurosurgery 20070501
Title: Conversion to combined therapy with sirolimus and mycophenolate mofetil improved renal function in stable renal transplant recipients.
Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20070501
Title: Sirolimus-eluting stents in real-world patients with ST-segment elevation acute myocardial infarction.
Journal: International heart journal 20070501
Title: Two cases of very late stent thrombosis after implantation of a sirolimus-eluting stent presenting as AMI.
Journal: International heart journal 20070501
Title: [Angioplasty stenting with Sirolimus (rapamycin) eluting stents in type 2 diabetic patients].
Journal: Revista medica de Chile 20070501
Title: Clinical development of mTOR inhibitors: a focus on lymphoma.
Journal: Reviews on recent clinical trials 20070501
Title: Rapamycin enhances the number of alloantigen-induced human CD103+CD8+ regulatory T cells in vitro.
Journal: Transplantation 20070427
Title: Rapamycin inhibits proliferation of Epstein-Barr virus-positive B-cell lymphomas through modulation of cell-cycle protein expression.
Journal: Transplantation 20070427
Title: Regulation of survivin expression by IGF-1/mTOR signaling.
Journal: Oncogene 20070426
Title: Clopidogrel and long-term outcomes after drug-eluting stent implantation.
Journal: JAMA 20070425
Title: Clopidogrel and long-term outcomes after drug-eluting stent implantation.
Journal: JAMA 20070425
Title: Clopidogrel and long-term outcomes after drug-eluting stent implantation.
Journal: JAMA 20070425
Title: Clopidogrel and long-term outcomes after drug-eluting stent implantation.
Journal: JAMA 20070425
Title: [Late stent thrombosis with drug eluting stents: disturbing signals on the radar].
Journal: Ugeskrift for laeger 20070423
Title: p21-activated kinase 1 is activated through the mammalian target of rapamycin/p70 S6 kinase pathway and regulates the replication of hepatitis C virus in human hepatoma cells.
Journal: The Journal of biological chemistry 20070420
Title: Distinct EBV and CMV reactivation patterns following antibody-based immunosuppressive regimens in patients with severe aplastic anemia.
Journal: Blood 20070415
Title: Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML.
Journal: Blood 20070415
Title: Mammalian target of rapamycin is activated in human gastric cancer and serves as a target for therapy in an experimental model.
Journal: International journal of cancer 20070415
Title: PI3K(p110alpha) inhibitors as anti-cancer agents: minding the heart.
Journal: Cell cycle (Georgetown, Tex.) 20070415
Title: Comparison of three-year clinical outcome of sirolimus- and paclitaxel-eluting stents versus bare metal stents in patients with ST-segment elevation myocardial infarction (from the RESEARCH and T-SEARCH Registries).
Journal: The American journal of cardiology 20070415
Title: Evaluation by optical coherence tomography of neointimal coverage of sirolimus-eluting stent three months after implantation.
Journal: The American journal of cardiology 20070415
Title: Analysis of 36 reported cases of late thrombosis in drug-eluting stents placed in coronary arteries.
Journal: The American journal of cardiology 20070415
Title: Safety of sirolimus-eluting stenting and its effect on restenosis in patients with unstable angina pectoris (a SIRIUS substudy).
Journal: The American journal of cardiology 20070415
Title: Cyphering the complexity of coronary artery disease using the syntax score to predict clinical outcome in patients with three-vessel lumen obstruction undergoing percutaneous coronary intervention.
Journal: The American journal of cardiology 20070415
Title: Therapeutic effect of rapamycin on gallbladder cancer in a transgenic mouse model.
Journal: Cancer research 20070415
Title: Kidney transplantation with sirolimus and mycophenolate mofetil-based immunosuppression: 5-year results of a randomized prospective trial compared to calcineurin inhibitor drugs.
Journal: Transplantation 20070415
Title: Sirolimus-eluting stent showed better one-year outcomes than paclitaxel-eluting stent in a real life setting of coronary intervention in Koreans.
Journal: International journal of cardiology 20070412
Title: AKT activity regulates the ability of mTOR inhibitors to prevent angiogenesis and VEGF expression in multiple myeloma cells.
Journal: Oncogene 20070405
Title: Late stent thrombosis: a not negligible issue after drug-eluting stent implantation.
Journal: Chinese medical journal 20070405
Title: Sirolimus-eluting cobalt alloyed stents in treating patients with coronary artery disease: six-month angiographic and one-year clinical follow-up result. A prospective, historically controlled, multi-center clinical study.
Journal: Chinese medical journal 20070405
Title: Long-term outcomes following drug-eluting stent implantation in unprotected left main bifurcation lesions.
Journal: Chinese medical journal 20070405
Title: Drug-eluting stent for the treatment of small coronary lesion: comparison between sirolimus- and paclitaxel-eluting stent.
Journal: Chinese medical journal 20070405
Title: A comparison of clinical and angiographic outcomes after Excel bioabsorbable polymer versus Firebird durable polymer rapamycin-eluting stent for the treatment of coronary artery disease in a 'real world' setting: six-month follow-up results.
Journal: Chinese medical journal 20070405
Title: Type-D personality predicts chronic anxiety following percutaneous coronary intervention in the drug-eluting stent era.
Journal: Journal of affective disorders 20070401
Title: A HPLC-mass spectrometric method suitable for the therapeutic drug monitoring of everolimus.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070401
Title: Neointimal coverage of sirolimus-eluting stents at 6-month follow-up: evaluated by optical coherence tomography.
Journal: European heart journal 20070401
Title: Extended follow-up of methotrexate-free immunosuppression using sirolimus and tacrolimus in related and unrelated donor peripheral blood stem cell transplantation.
Journal: Blood 20070401
Title: Mechanism of apoptosis induced by IFN-alpha in human myeloma cells: role of Jak1 and Bim and potentiation by rapamycin.
Journal: Cellular signalling 20070401
Title: A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling.
Journal: The Biochemical journal 20070401
Title: Rapamycin is a neuroprotective treatment for traumatic brain injury.
Journal: Neurobiology of disease 20070401
Title: Rapamycin: brain excitability studied in vitro.
Journal: Epilepsia 20070401
Title: Ssh4, Rcr2 and Rcr1 affect plasma membrane transporter activity in Saccharomyces cerevisiae.
Journal: Genetics 20070401
Title: Chronic alcohol consumption alters mammalian target of rapamycin (mTOR), reduces ribosomal p70s6 kinase and p4E-BP1 levels in mouse cerebral cortex.
Journal: Experimental neurology 20070401
Title: Accurate determination of an immunosuppressant in stented swine tissues with LC-MS/MS.
Journal: Analytical and bioanalytical chemistry 20070401
Title: Inhibition of the mammalian target of rapamycin impedes lymphangiogenesis.
Journal: Kidney international 20070401
Title: Mutasynthesis - uniting chemistry and genetics for drug discovery.
Journal: Trends in biotechnology 20070401
Title: Gonadal impact of target of rapamycin inhibitors (sirolimus and everolimus) in male patients: an overview.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20070401
Title: Hemolytic uremic syndrome following Campath-1H induction.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20070401
Title: No recurrence of Kaposi's sarcoma in a case of renal retransplantation under a calcineurin inhibitor free immunosuppressive regimen: first report.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20070401
Title: Differential modulation of mitogen driven proliferation and homeostasis driven proliferation of T cells by rapamycin, Ly294002 and chlorophyllin.
Journal: Molecular immunology 20070401
Title: The effect of immunosuppressive drug rapamycin on regulatory CD4+CD25+Foxp3+T cells in mice.
Journal: Transplant immunology 20070401
Title: Rapamycin inhibits cell growth by induction of apoptosis on hepatocellular carcinoma cells in vitro.
Journal: Transplant immunology 20070401
Title: Effect of sirolimus treatment on gene expression in renal transplant patients.
Journal: World journal of surgery 20070401
Title: PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr.
Journal: International immunology 20070401
Title: Limitation by p70 S6 kinase of platelet-derived growth factor-BB-induced interleukin 6 synthesis in osteoblast-like MC3T3-E1 cells.
Journal: Metabolism: clinical and experimental 20070401
Title: Drug-eluting stent-induced left anterior descending coronary artery aneurysm: repair by pericardial patch--where are we headed?
Journal: The Annals of thoracic surgery 20070401
Title: Incidence of side-effects of ticlopidine after sirolimus-eluting stent implantation.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20070401
Title: Effects of immunosuppressive drugs on in vitro neogenesis of human islets: mycophenolate mofetil inhibits the proliferation of ductal cells.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070401
Title: Diabetic retinopathy and coronary implantation of sirolimus-eluting stents.
Journal: Journal of interventional cardiology 20070401
Title: Potential therapeutic applications of autophagy.
Journal: Nature reviews. Drug discovery 20070401
Title: Recommendations for the use of everolimus (Certican) in heart transplantation: results from the second German-Austrian Certican Consensus Conference.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070401
Title: Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070401
Title: Comparison of vessel response following sirolimus-eluting stent implantation as assessed by serial 3-D intravascular ultrasound study.
Journal: The Journal of invasive cardiology 20070401
Title: Sirolimus-eluting stents for the treatment of bare-metal in-stent restenosis: long-term clinical follow up.
Journal: The Journal of invasive cardiology 20070401
Title: Late stent thrombosis associated with coronary aneurysm formation after sirolimus-eluting stent implantation.
Journal: The Journal of invasive cardiology 20070401
Title: Activation of mitogen-activated protein kinase by hepatocyte growth factor is stimulated by both alpha1- and beta2-adrenergic agonists in primary cultures of adult rat hepatocytes.
Journal: Journal of pharmacological sciences 20070401
Title: [Effect of Rapamycin on CD4(+) CD25(+) regulatory T cells in allo-transplantation tolerance model].
Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20070401
Title: How to control lymphangiogenesis: a novel role for rapamycin.
Journal: Kidney international 20070401
Title: [Induction effect of rapamycin combined paclitaxel on apoptosis of ovarian cancer cell lines A2780 and SKOV3 and the molecular mechanism].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20070401
Title: Drug-eluting stents show delayed healing: paclitaxel more pronounced than sirolimus.
Journal: European heart journal 20070401
Title: Zotarolimus, a novel sirolimus analogue with potent anti-proliferative activity on coronary smooth muscle cells and reduced potential for systemic immunosuppression.
Journal: Journal of cardiovascular pharmacology 20070401
Title: Conversion from a calcineurin inhibitor-based immunosuppressive regimen to everolimus in renal transplant recipients: effect on renal function and proteinuria.
Journal: Transplantation proceedings 20070401
Title: Case report of a kidney transplant recipient converted to everolimus due to malignancy: resolution of bronchiolitis obliterans organizing pneumonia without everolimus discontinuation.
Journal: Transplantation proceedings 20070401
Title: Sirolimus-eluting versus bare stents after suboptimal infrapopliteal angioplasty for critical limb ischemia: enduring 1-year angiographic and clinical benefit.
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20070401
Title: Participation of phosphatidyl inositol 3-kinase/protein kinase B and ERK1/2 pathways in interleukin-1beta stimulation of lactate production in Sertoli cells.
Journal: Reproduction (Cambridge, England) 20070401
Title: Cost-effectiveness of sirolimus-eluting stents in percutaneous coronary interventions in Brazil.
Journal: Arquivos brasileiros de cardiologia 20070401
Title: Sirolimus-eluting coronary stents: a review.
Journal: Vascular health and risk management 20070401
Title: [Procedural success and 10-month outcome between Cypher and TAXUS drug-eluting stents for the treatment of in-stent restenosis].
Journal: Zhonghua xin xue guan bing za zhi 20070401
Title: [Very late stent thrombosis after implantation of sirolimus eluting coronary stents].
Journal: Zhonghua xin xue guan bing za zhi 20070401
Title: [Re-occurred acute myocardial infarction caused by very late thrombosis 36 months after implantation of sirolimus eluting stent: a case report].
Journal: Zhonghua xin xue guan bing za zhi 20070401
Title: Does addition of estradiol improve the efficacy of a rapamycin-eluting stent? Results of the ISAR-PEACE randomized trial.
Journal: Journal of the American College of Cardiology 20070327
Title: Epithelial-to-mesenchymal transition of human proximal tubular epithelial cells: effects of rapamycin, mycophenolate, cyclosporin, azathioprine, and methylprednisolone.
Journal: Transplantation 20070327
Title: Dual EGFR and mTOR targeting in squamous cell carcinoma models, and development of early markers of efficacy.
Journal: British journal of cancer 20070326
Title: Silencing mammalian target of rapamycin signaling by small interfering RNA enhances rapamycin-induced autophagy in malignant glioma cells.
Journal: Oncogene 20070322
Title: Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism.
Journal: Oncogene 20070322
Title: For organ transplant recipients, cancer threatens long-term survival.
Journal: Journal of the National Cancer Institute 20070321
Title: Age-based clinical and angiographic outcomes after sirolimus-eluting stent implantation in patients with coronary artery disease.
Journal: Chinese medical journal 20070320
Title: Target of rapamycin (TOR) signaling controls epithelial morphogenesis in the vertebrate intestine.
Journal: Developmental biology 20070315
Title: Two endoplasmic reticulum-associated degradation (ERAD) systems for the novel variant of the mutant dysferlin: ubiquitin/proteasome ERAD(I) and autophagy/lysosome ERAD(II).
Journal: Human molecular genetics 20070315
Title: Results and predictors of angiographic restenosis and long-term adverse cardiac events after drug-eluting stent implantation for aorto-ostial coronary artery disease.
Journal: The American journal of cardiology 20070315
Title: Frequency of coronary arterial late angiographic stent thrombosis (LAST) in the first six months: outcomes with drug-eluting stents versus bare metal stents.
Journal: The American journal of cardiology 20070315
Title: In vivo and in vitro effect of sirolimus on insulin secretion.
Journal: Transplantation 20070315
Title: Rapamycin promotes emergence of IL-10-secreting donor lymphocyte infusion-derived T cells without compromising their graft-versus-leukemia reactivity.
Journal: Transplantation 20070315
Title: RAD001 (Everolimus) delays tumor onset and progression in a transgenic mouse model of ovarian cancer.
Journal: Cancer research 20070315
Title: [Pharmacodynamics of China-made rapamycin-polylactide-co-glycolide peripheral arterial eluting stent membrane: in vitro experiment].
Journal: Zhonghua yi xue za zhi 20070313
Title: AKT and CDK5/p35 mediate brain-derived neurotrophic factor induction of DARPP-32 in medium size spiny neurons in vitro.
Journal: The Journal of biological chemistry 20070309
Title: Stent thrombosis in randomized clinical trials of drug-eluting stents.
Journal: The New England journal of medicine 20070308
Title: Long-term outcomes with drug-eluting stents versus bare-metal stents in Sweden.
Journal: The New England journal of medicine 20070308
Title: Analysis of 14 trials comparing sirolimus-eluting stents with bare-metal stents.
Journal: The New England journal of medicine 20070308
Title: Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents.
Journal: The New England journal of medicine 20070308
Title: A pooled analysis of data comparing sirolimus-eluting stents with bare-metal stents.
Journal: The New England journal of medicine 20070308
Title: Unanswered questions--drug-eluting stents and the risk of late thrombosis.
Journal: The New England journal of medicine 20070308
Title: Late thrombosis of a drug-eluting stent overlapped in the in-stent restenotic lesion of a bare metal stent.
Journal: International journal of cardiology 20070302
Title: Regulation of translation factors eIF4GI and 4E-BP1 during recovery of protein synthesis from inhibition by p53.
Journal: Cell death and differentiation 20070301
Title: The YCR079w gene confers a rapamycin-resistant function and encodes the sixth type 2C protein phosphatase in Saccharomyces cerevisiae.
Journal: FEMS yeast research 20070301
Title: Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling.
Journal: Blood 20070301
Title: Rapamycin inhibits proliferation of estrogen-receptor-positive breast cancer cells.
Journal: The Journal of surgical research 20070301
Title: mTOR-dependent synthesis of Bcl-3 controls the retraction of fibrin clots by activated human platelets.
Journal: Blood 20070301
Title: Metabolism of sirolimus in the presence or absence of cyclosporine by genotyped human liver microsomes and recombinant cytochromes P450 3A4 and 3A5.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070301
Title: In vivo inhibition of human hepatocellular carcinoma related angiogenesis by vinblastine and rapamycin.
Journal: Histology and histopathology 20070301
Title: Sirolimus causes relaxation of human vascular smooth muscle: a novel action of sirolimus mediated via ATP-sensitive potassium channels.
Journal: The Journal of pharmacology and experimental therapeutics 20070301
Title: Modeling of degradation and drug release from a biodegradable stent coating.
Journal: Journal of biomedical materials research. Part A 20070301
Title: Role of protein tyrosine phosphatases in the regulation of interferon-{gamma}-induced macrophage nitric oxide generation: implication of ERK pathway and AP-1 activation.
Journal: Journal of leukocyte biology 20070301
Title: Opposite effects of tor1 and tor2 on nitrogen starvation responses in fission yeast.
Journal: Genetics 20070301
Title: Negative regulation by p70 S6 kinase of FGF-2-stimulated VEGF release through stress-activated protein kinase/c-Jun N-terminal kinase in osteoblasts.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20070301
Title: Utility of three-dimensional reconstruction of coronary angiography to guide percutaneous coronary intervention.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070301
Title: One-year results with extended-release tacrolimus/MMF, tacrolimus/MMF and cyclosporine/MMF in de novo kidney transplant recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070301
Title: Mycophenolate mofetil/sirolimus compared to other common immunosuppressive regimens in kidney transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070301
Title: Calcineurin inhibitor-free protocols: risks and benefits.
Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20070301
Title: Mycotic pseudoaneurysm of the left circumflex coronary artery: a fatal complication following drug-eluting stent implantation.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070301
Title: Clobetasol ameliorates aphthous ulceration in renal transplant patients on sirolimus.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070301
Title: A clickable inhibitor reveals context-dependent autoactivation of p90 RSK.
Journal: Nature chemical biology 20070301
Title: FK506 binding protein 12/12.6 depletion increases endothelial nitric oxide synthase threonine 495 phosphorylation and blood pressure.
Journal: Hypertension (Dallas, Tex. : 1979) 20070301
Title: Proliferation signal inhibitors in cardiac transplantation.
Journal: Current opinion in cardiology 20070301
Title: New advances in antirejection therapy.
Journal: Current opinion in cardiology 20070301
Title: Regulatory T cells and T cell depletion: role of immunosuppressive drugs.
Journal: Journal of the American Society of Nephrology : JASN 20070301
Title: Pulmonary alveolar proteinosis: a rare pulmonary toxicity of sirolimus.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20070301
Title: Chemical rescue of cleft palate and midline defects in conditional GSK-3beta mice.
Journal: Nature 20070301
Title: Rapamycin-mediated G1 arrest involves regulation of the Cdk inhibitor Sic1 in Saccharomyces cerevisiae.
Journal: Molecular microbiology 20070301
Title: The treatment of multifocal choroiditis associated choroidal neovascularization with sirolimus (rapamycin).
Journal: Acta ophthalmologica Scandinavica 20070301
Title: Repeated drug-eluting stent implantation for drug-eluting stent restenosis: the same or a different stent.
Journal: American heart journal 20070301
Title: Angiographic analysis of pattern of late luminal loss in sirolimus- and paclitaxel-eluting stents.
Journal: The American journal of cardiology 20070301
Title: Comparison of effectiveness of bare metal stents versus drug-eluting stents in large (> or =3.5 mm) coronary arteries.
Journal: The American journal of cardiology 20070301
Title: An anti-aging drug today: from senescence-promoting genes to anti-aging pill.
Journal: Drug discovery today 20070301
Title: Mammalian target of rapamycin inhibitors as possible adjuvant therapy for microscopic residual disease in head and neck squamous cell cancer.
Journal: Cancer research 20070301
Title: Monitoring antitumor efficacy of rapamycin in Kaposi sarcoma.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20070301
Title: Islet transplantation.
Journal: The New England journal of medicine 20070301
Title: In-stent pseudo-restenosis due to an organized thrombus six months after implantation of a sirolimus-eluting stent.
Journal: The Journal of invasive cardiology 20070301
Title: Sirolimus-eluting stent implantation outside a previous stent.
Journal: The Journal of invasive cardiology 20070301
Title: Sirolimus-associated chronic pyogenic periungual infection.
Journal: Kidney international 20070301
Title: Reduced progression of endometrial hyperplasia with oral mTOR inhibition in the Pten heterozygote murine model.
Journal: American journal of obstetrics and gynecology 20070301
Title: Calcineurin inhibitor-free immunosuppression using everolimus (Certican) in maintenance heart transplant recipients: 6 months' follow-up.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070301
Title: Acute sirolimus pulmonary toxicity in an infant heart transplant recipient: case report and literature review.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070301
Title: [Gene therapy for osteoarticular disorders].
Journal: Medecine sciences : M/S 20070301
Title: The role of immunosuppressive drugs in aggravating renal ischemia and reperfusion injury.
Journal: Transplantation proceedings 20070301
Title: A role for HO-1 in renal function impairment in animals subjected to ischemic and reperfusion injury and treated with immunosuppressive drugs.
Journal: Transplantation proceedings 20070301
Title: Proteinuria in transplant patients associated with sirolimus.
Journal: Transplantation proceedings 20070301
Title: The effects of rapamycin in the progression of renal fibrosis.
Journal: Transplantation proceedings 20070301
Title: Five-year follow-up after late conversion from calcineurin inhibitors to sirolimus in patients with chronic renal allograft dysfunction.
Journal: Transplantation proceedings 20070301
Title: Is the malononitrilamide FK778 better for the prevention of acute or chronic rejection?
Journal: Transplantation proceedings 20070301
Title: Upstream signaling inhibition enhances rapamycin effect on growth of kidney cancer cells.
Journal: Urology 20070301
Title: Left main coronary artery stenosis: state-of-the-art.
Journal: Current problems in cardiology 20070301
Title: In-stent restenosis: 3 novel solutions show promise for heart patients. Stopping regrowth of plaque inside stents is a priority in reducing the need for repeat revascularizations.
Journal: DukeMedicine healthnews 20070301
Title: Initial and long-term outcomes of sirolimus-eluting stents for calcified lesions compared with bare-metal stents.
Journal: International heart journal 20070301
Title: Chemokines and chemokine receptors in renal transplantation--from bench to bedside.
Journal: Acta physiologica Hungarica 20070301
Title: [Treatment of intrastent restenosis by drug eluting stents: experience from one cardiology centre].
Journal: Archives des maladies du coeur et des vaisseaux 20070301
Title: [Analysis of the mechanisms of thrombosis after implantation of drug-eluting stents].
Journal: Zhonghua nei ke za zhi 20070301
Title: [Short and long-term therapeutic efficacy of drug-eluting stents (Firebird) for the treatment of coronary artery disease].
Journal: Zhonghua xin xue guan bing za zhi 20070301
Title: Immunosuppression strategies in kidney transplantation.
Journal: Medicine and health, Rhode Island 20070301
Title: Sirolimus: defining nephrotoxicity in the renal transplant recipient.
Journal: Clinical journal of the American Society of Nephrology : CJASN 20070301
Title: High sirolimus levels may induce focal segmental glomerulosclerosis de novo.
Journal: Clinical journal of the American Society of Nephrology : CJASN 20070301
Title: Nanomedicines in renal transplant rejection--focus on sirolimus.
Journal: International journal of nanomedicine 20070301
Title: Effects of everolimus on cellular and humoral immune processes leading to chronic allograft nephropathy in a rat model with sensitized recipients.
Journal: Transplantation 20070227
Title: [Expression of connective tissue growth factor in renal interstitial fibrosis after ureteral obstruction and effects of rapamycin thereupon: experiment with rats].
Journal: Zhonghua yi xue za zhi 20070227
Title: Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large two-institutional cohort study.
Journal: Lancet (London, England) 20070224
Title: Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.
Journal: The Journal of biological chemistry 20070223
Title: A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation.
Journal: Oncogene 20070222
Title: [Drug eluting stents: long term results in clinical practice. Comparison between rapamycin and paclitaxel eluting stents].
Journal: Medicina clinica 20070217
Title: Rottlerin inhibits human T cell responses.
Journal: Biochemical pharmacology 20070215
Title: Incidence and clinical impact of coronary stent fracture after sirolimus-eluting stent implantation.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070215
Title: Stent fracture associated with drug-eluting stents: clinical characteristics and implications.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070215
Title: Detection of vascular endothelial growth factor (VEGF) and VEGF receptors Flt-1 and KDR in canine mastocytoma cells.
Journal: Veterinary immunology and immunopathology 20070215
Title: Treatment of recurrent pulmonary vein stenoses with endovascular stenting and adjuvant oral sirolimus.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070215
Title: A role for mammalian target of rapamycin in regulating T cell activation versus anergy.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20070215
Title: Long-term graft outcomes after steroid withdrawal in African American kidney transplant recipients receiving sirolimus and tacrolimus.
Journal: Transplantation 20070215
Title: TSC1 sets the rate of ribosome export and protein synthesis through nucleophosmin translation.
Journal: Cancer research 20070215
Title: Akt/TSC/mTOR activation by the KSHV G protein-coupled receptor: emerging insights into the molecular oncogenesis and treatment of Kaposi's sarcoma.
Journal: Cell cycle (Georgetown, Tex.) 20070215
Title: Selective clearance of macrophages in atherosclerotic plaques by autophagy.
Journal: Journal of the American College of Cardiology 20070213
Title: Amino acid limitation induces expression of ATF5 mRNA at the post-transcriptional level.
Journal: Life sciences 20070206
Title: Randomized comparison of sirolimus and paclitaxel drug-eluting stents for long lesions in the left anterior descending artery: an intravascular ultrasound study.
Journal: Journal of the American College of Cardiology 20070206
Title: Effectiveness of drug-eluting stents in patients with bare-metal in-stent restenosis: meta-analysis of randomized trials.
Journal: Journal of the American College of Cardiology 20070206
Title: Development of coronary aneurysm after drug-eluting stent implantation.
Journal: Annals of internal medicine 20070206
Title: ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.
Journal: Cell death and differentiation 20070201
Title: Case report: Corticosteroid-resistant nephrotic syndrome: treatment with rapamune.
Journal: Pediatric nephrology (Berlin, Germany) 20070201
Title: mTOR signaling in the hippocampus is necessary for memory formation.
Journal: Neurobiology of learning and memory 20070201
Title: Rapamycin inhibits the growth and muscle-sparing effects of clenbuterol.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20070201
Title: Antiproliferative activity of RAD001 (everolimus) as a single agent and combined with other agents in mantle cell lymphoma.
Journal: Leukemia 20070201
Title: Antiproliferative agents alter vascular plasminogen activator inhibitor-1 expression: a potential prothrombotic mechanism of drug-eluting stents.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20070201
Title: Aspects of mTOR biology and the use of mTOR inhibitors in non-Hodgkin's lymphoma.
Journal: Cancer treatment reviews 20070201
Title: Is late stent thrombosis in drug-eluting stents a real clinical issue? A single-center experience and review of the literature.
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20070201
Title: Short- and long-term effects of cytochalasin D, paclitaxel and rapamycin on wall thickening in experimental porcine vein grafts.
Journal: Cardiovascular research 20070201
Title: [Coronary stents and anaesthesia: it is time to have national data].
Journal: Annales francaises d'anesthesie et de reanimation 20070201
Title: Relocation of minimal luminal diameter after bare metal and drug-eluting stent implantation: incidence and impact on angiographic late loss.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070201
Title: CYP3A5 genotype markedly influences the pharmacokinetics of tacrolimus and sirolimus in kidney transplant recipients.
Journal: Clinical pharmacology and therapeutics 20070201
Title: Effectiveness and safety of the sirolimus-eluting stents coated with bioabsorbable polymer coating in human coronary arteries.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070201
Title: Late restenosis following placement of a sirolimus eluting stent for in-stent restenosis.
Journal: Heart, lung & circulation 20070201
Title: Combining an mTOR antagonist and receptor tyrosine kinase inhibitors for the treatment of prostate cancer.
Journal: Cancer biology & therapy 20070201
Title: Severe psoriasis treated with a new macrolide: everolimus.
Journal: The British journal of dermatology 20070201
Title: Pharmacodynamics of T-cell function for monitoring immunosuppression.
Journal: Cell proliferation 20070201
Title: Switching from tacrolimus to sirolimus halts the appearance of new sebaceous neoplasms in Muir-Torre syndrome.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070201
Title: Emerging thrombotic effects of drug eluting stents.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20070201
Title: Evaluation of the efficacy and safety of a slow conversion from calcineurin inhibitor- to sirolimus-based therapies in maintenance renal-transplant patients presenting with moderate renal insufficiency.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20070201
Title: Induction of chimerism in rhesus macaques through stem cell transplant and costimulation blockade-based immunosuppression.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070201
Title: Further delineation of the continuous human neoplastic enterochromaffin cell line, KRJ-I, and the inhibitory effects of lanreotide and rapamycin.
Journal: Journal of molecular endocrinology 20070201
Title: Impaired endothelial vasomotor function after sirolimus-eluting stent implantation.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20070201
Title: Late angiographic stent thrombosis after sirolimus-eluting stent implantation.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20070201
Title: Novel bioengineered small caliber vascular graft with excellent one-month patency.
Journal: The Annals of thoracic surgery 20070201
Title: Impact of pharmacometric reviews on new drug approval and labeling decisions--a survey of 31 new drug applications submitted between 2005 and 2006.
Journal: Clinical pharmacology and therapeutics 20070201
Title: Comparison of drug-eluting versus bare metal stents on later frequency of acute myocardial infarction and death.
Journal: The American journal of cardiology 20070201
Title: Outcome of overlapping heterogenous drug-eluting stents and of overlapping drug-eluting and bare metal stents.
Journal: The American journal of cardiology 20070201
Title: Sirolimus therapy of focal segmental glomerulosclerosis is associated with nephrotoxicity.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20070201
Title: The clinical outcome of percutaneous treatment of bifurcation lesions in multivessel coronary artery disease with the sirolimus-eluting stent: insights from the Arterial Revascularization Therapies Study part II (ARTS II).
Journal: European heart journal 20070201
Title: Bivalirudin versus heparin plus glycoprotein IIb/IIIa inhibitors in drug-eluting stent implantations in the absence of acute myocardial infarction: clinical and economic results.
Journal: The Journal of invasive cardiology 20070201
Title: Bivalirudin and DES: a PCI strategy that pays.
Journal: The Journal of invasive cardiology 20070201
Title: Fractured DES with a patent coronary artery: clinical implications.
Journal: The Journal of invasive cardiology 20070201
Title: Targeting mammalian target of rapamycin (mTOR) for health and diseases.
Journal: Drug discovery today 20070201
Title: Interplay of PI3K and cAMP/PKA signaling, and rapamycin-hypersensitivity in TGFbeta1 enhancement of FSH-stimulated steroidogenesis in rat ovarian granulosa cells.
Journal: The Journal of endocrinology 20070201
Title: American Society of Hematology--48th Annual Meeting and Exposition. Treatments for leukemia and lymphoma. 9-12 December 2006 Orlando, FL, USA.
Journal: IDrugs : the investigational drugs journal 20070201
Title: American Society of Hematology--48th Annual Meeting and Exposition. Updates on therapies. 9-12 December 2006 Orlando, FL, USA.
Journal: IDrugs : the investigational drugs journal 20070201
Title: Randomized, double-blind, multicenter study of the Endeavor zotarolimus-eluting phosphorylcholine-encapsulated stent for treatment of native coronary artery lesions. Clinical and angiographic results of the ENDEAVOR II Trial.
Journal: Minerva cardioangiologica 20070201
Title: Keeping a high standard in quantitative analyses, meta-analyses, and systematic reviews.
Journal: European heart journal 20070201
Title: TCT Daily: Cypher more effective for long lesions.
Journal: Journal of interventional cardiology 20070201
Title: TCT Daily: ZOMAXX I--mixed results with zotarolimus-eluting stent.
Journal: Journal of interventional cardiology 20070201
Title: Adverse clinical events in patients treated with sirolimus-eluting stents: the impact of Type D personality.
Journal: European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20070201
Title: Validation of immunological biomarkers for the pharmacodynamic monitoring of immunosuppressive drugs in humans.
Journal: Therapeutic drug monitoring 20070201
Title: Serum sickness-like reactions after placement of sirolimus-eluting stents.
Journal: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20070201
Title: Requirements of phosphatidylinositol-3 kinase and mammalian target of rapamycin for estrogen-induced proliferation in uterine leiomyoma- and myometrium-derived cell lines.
Journal: American journal of obstetrics and gynecology 20070201
Title: Optimizing the development of targeted agents in pancreatic cancer: tumor fine-needle aspiration biopsy as a platform for novel prospective ex vivo drug sensitivity assays.
Journal: Molecular cancer therapeutics 20070201
Title: Combination of sublethal concentrations of epidermal growth factor receptor inhibitor and microtubule stabilizer induces apoptosis of glioblastoma cells.
Journal: Molecular cancer therapeutics 20070201
Title: Symptomatic failure after sirolimus-eluting stent implantation: a rare but challenging condition.
Journal: The Canadian journal of cardiology 20070201
Title: Orally administered rapamycin does not modify rat aortic vascular tone.
Journal: Journal of cardiovascular pharmacology 20070201
Title: [Progress on reasech of drug-coated stent].
Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20070201
Title: Thrombotic microangiopathy in a sirolimus-treated renal transplant patient receiving gemcitabine for lung cancer.
Journal: Clinical nephrology 20070201
Title: [Janus tacrolimus-eluting carbostent. Immediate and medium-term clinical results].
Journal: Revista espanola de cardiologia 20070201
Title: The Development of rapamycin as an orphan drug.
Journal: Clinical advances in hematology & oncology : H&O 20070201
Title: Possible predictors of target lesion revascularization after drug-eluting stent implantation.
Journal: Journal of cardiology 20070201
Title: Proximal left anterior descending coronary artery revascularization with drug-eluting stents.
Journal: Arquivos brasileiros de cardiologia 20070201
Title: Impact of stable versus unstable coronary artery disease on 1-year outcome in elective patients undergoing multivessel revascularization with sirolimus-eluting stents: a subanalysis of the ARTS II trial.
Journal: Journal of the American College of Cardiology 20070130
Title: Unilateral upper extremity edema associated with sirolimus in a heart transplant patient.
Journal: Transplantation 20070127
Title: Ligand-regulated peptide aptamers that inhibit the 5'-AMP-activated protein kinase.
Journal: Journal of molecular biology 20070126
Title: A 'silent' polymorphism in the MDR1 gene changes substrate specificity.
Journal: Science (New York, N.Y.) 20070126
Title: Nutrient starvation promotes condensin loading to maintain rDNA stability.
Journal: The EMBO journal 20070124
Title: [Comparison of stenting with sirolimus eluting stent and spot stenting with small vessel stent in treatment of small vessels with long lesions].
Journal: Zhonghua yi xue za zhi 20070123
Title: Phorbol 12-myristate 13-acetate and serum synergize to promote rapamycin-insensitive cell proliferation via protein kinase C-eta.
Journal: Oncogene 20070118
Title: Coronary artery stenting in a patient with angina pectoris caused by coronary artery dissection after blunt chest trauma.
Journal: International journal of cardiology 20070118
Title: Dilemma of drug-eluting stent implantation in a patient with systemic lupus erythematosus.
Journal: International journal of cardiology 20070118
Title: Long-term outcomes after management of restenosis or thrombosis of drug-eluting stents.
Journal: Journal of the American College of Cardiology 20070116
Title: Overexpression of the mTOR alpha4 phosphoprotein activates protein phosphatase 2A and increases Stat1alpha binding to PIAS1.
Journal: Molecular and cellular endocrinology 20070115
Title: Evaluating the activity of temsirolimus in neuroendocrine cancer.
Journal: British journal of cancer 20070115
Title: Sirolimus does not reduce receptor-mediated endocytosis of albumin in proximal tubule cells.
Journal: Transplantation 20070115
Title: [Drug-eluting or bare-metal stents in interventional cardiology. Theory and practice].
Journal: Medizinische Klinik (Munich, Germany : 1983) 20070115
Title: The role of mammalian target of rapamycin inhibitors in the treatment of advanced renal cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070115
Title: Clopidogrel use and long-term clinical outcomes after drug-eluting stent implantation.
Journal: JAMA 20070110
Title: Does clopidogrel each day keep stent thrombosis away?
Journal: JAMA 20070110
Title: Direct and indirect comparison meta-analysis demonstrates the superiority of sirolimus- versus paclitaxel-eluting stents across 5854 patients.
Journal: International journal of cardiology 20070102
Title: Coronary collateral function long after drug-eluting stent implantation.
Journal: Journal of the American College of Cardiology 20070102
Title: Attenuated coronary collateral function after drug-eluting stent implantation: a new downside of drug-eluting stents?
Journal: Journal of the American College of Cardiology 20070102
Title: Reactive oxygen species regulate insulin-induced VEGF and HIF-1alpha expression through the activation of p70S6K1 in human prostate cancer cells.
Journal: Carcinogenesis 20070101
Title: Rapamycin at subimmunosuppressive levels inhibits mesangial cell proliferation and extracellular matrix production.
Journal: American journal of physiology. Renal physiology 20070101
Title: A kinetically trapped intermediate of FK506 binding protein forms in vitro: chaperone machinery dominates protein folding in vivo.
Journal: Protein expression and purification 20070101
Title: Intramural delivery of Sirolimus prevents vascular remodeling following balloon injury.
Journal: Biochimica et biophysica acta 20070101
Title: Effects of rapamycin on cell proliferation and phosphorylation of mTOR and p70(S6K) in HepG2 and HepG2 cells overexpressing constitutively active Akt/PKB.
Journal: Biochimica et biophysica acta 20070101
Title: Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells.
Journal: Experimental neurology 20070101
Title: mTOR pathway as a target in tissue hypertrophy.
Journal: Annual review of pharmacology and toxicology 20070101
Title: In silico prediction of pregnane X receptor activators by machine learning approaches.
Journal: Molecular pharmacology 20070101
Title: Determination of everolimus in whole blood using the Abbott IMx sirolimus microparticle enzyme immunoassay.
Journal: Clinical biochemistry 20070101
Title: The pharmacodynamic effects of sirolimus and sirolimus-calcineurin inhibitor combinations on macrophage scavenger and nuclear hormone receptors.
Journal: Journal of pharmaceutical sciences 20070101
Title: Inhibition of restenosis development after mechanical injury: a new field of application for malononitrilamides?
Journal: Cardiology 20070101
Title: Constitutive activation of mTOR signaling pathway in post-transplant lymphoproliferative disorders.
Journal: Laboratory investigation; a journal of technical methods and pathology 20070101
Title: Mycophenolate acid inhibits endothelial NAD(P)H oxidase activity and superoxide formation by a Rac1-dependent mechanism.
Journal: Hypertension (Dallas, Tex. : 1979) 20070101
Title: A current problem in cardiology: very late thrombosis after implantation of sirolimus eluting stent.
Journal: Cardiology 20070101
Title: Persistent donor-specific alloreactivity may portend delayed liver rejection during drug minimization in children.
Journal: Frontiers in bioscience : a journal and virtual library 20070101
Title: The long-term value of sirolimus- and paclitaxel-eluting stents over bare metal stents in patients with diabetes mellitus.
Journal: European heart journal 20070101
Title: Epithelial-mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion.
Journal: The Journal of pathology 20070101
Title: Concurrent implantation of sirolimus- and paclitaxel-eluting stents in the same vessel.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070101
Title: Intracoronary radiation therapy for multi-drug resistant in-stent restenosis: initial clinical experience.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070101
Title: First-in-human implantation of a fully bioabsorbable drug-eluting stent: the BVS poly-L-lactic acid everolimus-eluting coronary stent.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070101
Title: Incidence and predictors of recurrent restenosis following implantation of drug-eluting stents for in-stent restenosis.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070101
Title: Two-year clinical outcome after coronary stenting of small vessels using 2.25-mm sirolimus- and paclitaxel-eluting stents: insight into the RESEARCH and T-SEARCH registries.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070101
Title: Everolimus is a potent inducer of erythroid differentiation and gamma-globin gene expression in human erythroid cells.
Journal: Acta haematologica 20070101
Title: Total synthesis of rapamycin.
Journal: Angewandte Chemie (International ed. in English) 20070101
Title: Response of U87 glioma xenografts treated with concurrent rapamycin and fractionated radiotherapy: possible role for thrombosis.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20070101
Title: Sirolimus-associated desquamative interstitial pneumonia.
Journal: Respiration; international review of thoracic diseases 20070101
Title: Drug-eluting stents: preventing restenosis.
Journal: Cardiology in review 20070101
Title: Shining a light on protein expression in living organisms.
Journal: Nature chemical biology 20070101
Title: Drug-eluting stents for the treatment of bifurcation lesions: a randomized comparison between paclitaxel and sirolimus stents.
Journal: American heart journal 20070101
Title: No robust conclusions to be drawn from clinical trials in the absence of an adequate control group.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20070101
Title: 12-month safety and efficacy of everolimus with reduced exposure cyclosporine in de novo renal transplant recipients.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20070101
Title: Selective survival of naturally occurring human CD4+CD25+Foxp3+ regulatory T cells cultured with rapamycin.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20070101
Title: Success rate of implantation and mid-term outcomes of the sirolimus-eluting stent.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20070101
Title: XIENCE V everolimus-eluting coronary stent system: a novel second generation drug-eluting stent.
Journal: Expert review of medical devices 20070101
Title: Sirolimus promotes tolerance for donor and recipient antigens after MHC class II disparate bone marrow transplantation in rats.
Journal: Experimental hematology 20070101
Title: Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin.
Journal: The American journal of pathology 20070101
Title: Phosphatase targets in TOR signaling.
Journal: Methods in molecular biology (Clifton, N.J.) 20070101
Title: Effect of rapamycin on hepatocyte function and proliferation induced by growth factors.
Journal: Chemotherapy 20070101
Title: Everolimus-induced mTOR inhibition selectively depletes macrophages in atherosclerotic plaques by autophagy.
Journal: Autophagy 20070101
Title: Sirolimus improves early microcirculation, but impairs regeneration after pancreatic ischemia-reperfusion injury.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070101
Title: Changes in renal function after clinical islet transplantation: four-year observational study.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070101
Title: Very late restenosis of a sirolimus-eluting stent after left main coronary artery stenting.
Journal: The Canadian journal of cardiology 20070101
Title: Rapamycin as an inhibitor of osteogenic differentiation in bone marrow-derived mesenchymal stem cells.
Journal: Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20070101
Title: Chronic allograft nephropathy score before sirolimus rescue predicts allograft function in renal transplant patients.
Journal: Transplantation proceedings 20070101
Title: Four cases of sirolimus-associated interstitial pneumonitis: identification of risk factors.
Journal: Transplantation proceedings 20070101
Title: New immunosuppresor strategies in the treatment of murine lupus nephritis.
Journal: Lupus 20070101
Title: [Hemolytic uremic syndrome due to sirolimus in a heart transplant recipient. Case report].
Journal: Revista espanola de cardiologia 20070101
Title: Drug-eluting stent implantation in ST-elevation acute myocardial infarction: 'real world' 30-day and mid-term results.
Journal: Cardiovascular revascularization medicine : including molecular interventions 20070101
Title: The ups and downs of sirolimus in kidney transplantation, and the importance of reporting negative findings.
Journal: The Netherlands journal of medicine 20070101
Title: Inferior results with basis immunosuppression with sirolimus in kidney transplantation.
Journal: The Netherlands journal of medicine 20070101
Title: Drug-eluting stent implantation in bifurcated lesions with balloon-crushing technique and 6 fr guiding catheter: immediate and mid-term results.
Journal: The Journal of invasive cardiology 20070101
Title: Treatment of a double-bifurcation lesion with sirolimus-eluting stents using the 'sleeve technique'.
Journal: The Journal of invasive cardiology 20070101
Title: Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance.
Journal: Molecular cancer 20070101
Title: How to treat recurrences of in-stent restenosis?
Journal: Internal medicine (Tokyo, Japan) 20070101
Title: Early steroid withdrawal therapy in renal transplant recipients: a steroid-free sirolimus and CellCept-based calcineurin inhibitor-minimization protocol.
Journal: Clinical transplantation 20070101
Title: The novel mTOR inhibitor RAD001 (everolimus) induces antiproliferative effects in human pancreatic neuroendocrine tumor cells.
Journal: Neuroendocrinology 20070101
Title: New therapeutics for soft-tissue sarcomas in adults.
Journal: Oncology (Williston Park, N.Y.) 20070101
Title: Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice.
Journal: Respiratory research 20070101
Title: Use of sirolimus in solid organ transplantation.
Journal: Drugs 20070101
Title: [Percutaneous coronary intervention for the elderly patients].
Journal: Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20070101
Title: Newly approved therapies for RCC and their effect on the standard of care.
Journal: Clinical advances in hematology & oncology : H&O 20070101
Title: A novel immunosuppressive agent, sirolimus, in the treatment of Kaposi's sarcoma in a renal transplant recipient.
Journal: Renal failure 20070101
Title: Do the benefits outweigh the risks with drug-eluting stents?
Journal: Scandinavian cardiovascular journal : SCJ 20070101
Title: Amino acids and insulin act additively to regulate components of the ubiquitin-proteasome pathway in C2C12 myotubes.
Journal: BMC molecular biology 20070101
Title: Angioedema in renal transplant recipients on sirolimus.
Journal: Dermatology (Basel, Switzerland) 20070101
Title: CCI-779 plus cisplatin is highly effective against human melanoma in a SCID mouse xenotranplantation model.
Journal: Pharmacology 20070101
Title: A potential screening tool for IPEX syndrome.
Journal: Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 20070101
Title: Angiographic and clinical outcome following sirolimus-eluting stent (Cypher) implantation. A single center experience.
Journal: International heart journal 20070101
Title: Molecularly targeted therapy for Kaposi's sarcoma in a kidney transplant patient: case report, 'what worked and what did not'.
Journal: BMC nephrology 20070101
Title: [Late localized aneurysmal dilations after sirolimus-eluting stents in 4 patients].
Journal: Zhonghua xin xue guan bing za zhi 20070101
Title: Incidence of late stent thrombosis with bare-metal, sirolimus, and paclitaxel stents.
Journal: Reviews in cardiovascular medicine 20070101
Title: Rapamycin-induced inhibition of HTLV-I LTR activity is rescued by c-Myb.
Journal: Retrovirology 20070101
Title: [Stents in interventional cardiology].
Journal: Medicina (Kaunas, Lithuania) 20070101
Title: Control of apoptosis in human multiple myeloma by insulin-like growth factor I (IGF-I).
Journal: Advances in cancer research 20070101
Title: Mechanisms of TSC-mediated control of synapse assembly and axon guidance.
Journal: PloS one 20070101
Title: Manipulating regulatory T cells.
Journal: Cytotherapy 20070101
Title: Rapamycin enriches for CD4(+) CD25(+) CD27(+) Foxp3(+) regulatory T cells in ex vivo-expanded CD25-enriched products from healthy donors and patients with multiple sclerosis.
Journal: Cytotherapy 20070101
Title: [Pro- and antitumor effects of the main immunosuppressive drugs used in the clinical practice of transplantation].
Journal: Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20070101
Title: Calcineurin inhibitor substitution with sirolimus vs. reduced-dose calcineurin inhibitor plus sirolimus is associated with improved renal dysfunction in heart transplant patients.
Journal: Clinical transplantation 20070101
Title: Factors influencing glomerular filtration rate in renal transplantation after cyclosporine withdrawal using sirolimus-based therapy: a multivariate analysis of results at five years.
Journal: Clinical transplantation 20070101
Title: Effects of sirolimus vs. calcineurin inhibitors on renal dysfunction after orthotopic liver transplantation.
Journal: Clinical transplantation 20070101
Title: Sirolimus inhibits key events of restenosis in vitro/ex vivo: evaluation of the clinical relevance of the data by SI/MPL- and SI/DES-ratios.
Journal: BMC cardiovascular disorders 20070101
Title: The next generation of drug-eluting stents: what's on the horizon?
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101
Title: Rapamycin for treatment of refractory dysthyroid compressive optic neuropathy.
Journal: Ophthalmic plastic and reconstructive surgery 20070101
Title: Engineering aspects of stents design and their translation into clinical practice.
Journal: Annali dell'Istituto superiore di sanita 20070101
Title: Surgical wound-healing complications in heart transplant recipients treated with rapamycin.
Journal: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20070101
Title: Saccharomyces cerevisiae FKBP12 binds Arabidopsis thaliana TOR and its expression in plants leads to rapamycin susceptibility.
Journal: BMC plant biology 20070101
Title: Immunosuppression on the horizon.
Journal: Heart failure clinics 20070101
Title: When is retransplantation a viable option?
Journal: Heart failure clinics 20070101
Title: Advanced renal cell carcinoma: current and emerging management strategies.
Journal: Drugs 20070101
Title: Neointimal hyperplasia persists at six months after sirolimus-eluting stent implantation in diabetic porcine.
Journal: Cardiovascular diabetology 20070101
Title: The making of a queen: TOR pathway is a key player in diphenic caste development.
Journal: PloS one 20070101
Title: Effects of rapamycin on active Heymann nephritis.
Journal: American journal of nephrology 20070101
Title: Successful surgical treatment of an infected right coronary artery aneurysm-to-right ventricle fistula after sirolimus-eluting stent implantation.
Journal: Internal medicine (Tokyo, Japan) 20070101
Title: mTOR inhibitors (rapamycin and its derivatives) and nitrogen containing bisphosphonates: bi-functional compounds for the treatment of bone tumours.
Journal: Current medicinal chemistry 20070101
Title: The search for endothelium friendly stents.
Journal: Medical device technology 20070101
Title: Regulation of hepatic oval cell proliferation by adenoviral mediated hepatocyte growth factor gene transfer and signal transduction inhibitors.
Journal: Hepato-gastroenterology 20070101
Title: Everolimus retards cyst growth and preserves kidney function in a rodent model for polycystic kidney disease.
Journal: Kidney & blood pressure research 20070101
Title: Roles of mTOR and STAT3 in autophagy induced by telomere 3' overhang-specific DNA oligonucleotides.
Journal: Autophagy 20070101
Title: The role of targeted therapy in metastatic renal cell carcinoma.
Journal: TheScientificWorldJournal 20070101
Title: Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death.
Journal: Autophagy 20070101
Title: Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy.
Journal: Molecular cancer 20070101
Title: Risk factors for impaired wound healing in sirolimus-treated renal transplant recipients.
Journal: Clinical transplantation 20070101
Title: Sirolimus exposure during the early post-transplant period reduces the risk of CMV infection relative to tacrolimus in renal allograft recipients.
Journal: Clinical transplantation 20070101
Title: Clinical outcomes of renal transplant recipients treated with enteric-coated mycophenolic acid vs. mycophenolate mofetil as a switch agent using a primary steroid-free rapamune and microemulsion cyclosporine protocol.
Journal: Clinical transplantation 20070101
Title: Comparison of sirolimus and everolimus in their effects on blood lipid profiles and haematological parameters in heart transplant recipients.
Journal: Clinical transplantation 20070101
Title: [Effect of angiogenesis inhibitors on renal cell carcinoma].
Journal: Magyar onkologia 20070101
Title: Immunosuppression for lung transplantation: evidence to date.
Journal: Drugs 20070101
Title: Rapamycin prevents early steps of the development of diabetic nephropathy in rats.
Journal: American journal of nephrology 20070101
Title: Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin module for acute myelogenous leukemia therapy: from bench to bedside.
Journal: Current medicinal chemistry 20070101
Title: Higher incidence of acute rejection in renal transplant recipients with low everolimus exposure.
Journal: Transplantation proceedings 20070101
Title: Sirolimus monotherapy in liver transplantation.
Journal: Transplantation proceedings 20070101
Title: Possible role of everolimus in improving renal function in long-term heart transplantation.
Journal: Transplantation proceedings 20070101
Title: Conversion to rapamycin immunosuppression for malignancy after kidney transplantation: case reports.
Journal: Transplantation proceedings 20070101
Title: Peritoneal leiomyosarcoma in a kidney transplant patient: a case report.
Journal: Transplantation proceedings 20070101
Title: Everolimus and mycophenolate mofetil sensitize human pancreatic cancer cells to gemcitabine in vitro: a novel adjunct to standard chemotherapy?
Journal: European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20070101
Title: T-cell function monitoring in stable renal transplant patients treated with sirolimus monotherapy.
Journal: Molecular diagnosis & therapy 20070101
Title: Roles of cytokines in the pathogenesis and therapy of type 1 diabetes.
Journal: Cell biochemistry and biophysics 20070101
Title: Small molecule enhancers of rapamycin-induced TOR inhibition promote autophagy, reduce toxicity in Huntington's disease models and enhance killing of mycobacteria by macrophages.
Journal: Autophagy 20070101
Title: Immunoassay determination of rapamycin: reliability of the method with respect to liquid chromatography mass spectrometric quantification.
Journal: Clinical transplantation 20070101
Title: The use of sirolimus in ganciclovir-resistant cytomegalovirus infections in renal transplant recipients.
Journal: Clinical transplantation 20070101
Title: Promising new targeted agents in head and neck cancer.
Journal: International journal of radiation oncology, biology, physics 20070101
Title: New drugs: ambrisentan, temsirolimus, and eculizumab.
Journal: Journal of the American Pharmacists Association : JAPhA 20070101
Title: Clinical proof-of-concept trial to assess the therapeutic effect of sirolimus in patients with autosomal dominant polycystic kidney disease: SUISSE ADPKD study.
Journal: BMC nephrology 20070101
Title: Prevention of murine lupus disease in (NZBxNZW)F1 mice by sirolimus treatment.
Journal: Lupus 20070101
Title: Hematopoietic stem cell transplantation across major genetic barriers.
Journal: Immunologic research 20070101
Title: Molecule of the month. Temsirolimus.
Journal: Drug news & perspectives 20070101
Title: Effects of controlled-released sirolimus from polymer matrices on human coronary artery smooth muscle cells.
Journal: Journal of biomaterials science. Polymer edition 20070101
Title: [Angiogenesis targeting in renal carcinomas].
Journal: Bulletin du cancer 20070101
Title: RAD inhibition of sarcoma growth: implications for laryngeal transplantation.
Journal: American journal of otolaryngology 20070101
Title: Tuberous sclerosis preclinical studies: timing of treatment, combination of a rapamycin analog (CCI-779) and interferon-gamma, and comparison of rapamycin to CCI-779.
Journal: BMC pharmacology 20070101
Title: Coupled down-regulation of mTOR and telomerase activity during fluorouracil-induced apoptosis of hepatocarcinoma cells.
Journal: BMC cancer 20070101
Title: [Clinical implications of coronary stents coated with drugs].
Journal: Terapevticheskii arkhiv 20070101
Title: [Lymphangioleiomyomatosis and translational medicine].
Journal: Medicina 20070101
Title: Development of an ultra-performance liquid chromatography technique coupled with mass spectrometry for the measurement of tacrolimus in micro-samples of whole blood, and its application on a pharmacokiinetic trial.
Journal: Arzneimittel-Forschung 20070101
Title: Clinical use of sirolimus-eluting stents.
Journal: Cardiovascular drug reviews 20070101
Title: Transcriptome of angiopoietin 1-activated human umbilical vein endothelial cells.
Journal: Endothelium : journal of endothelial cell research 20070101
Title: Conditional transgenesis using Dimerizable Cre (DiCre).
Journal: PloS one 20070101
Title: Unprotected left main coronary artery intervention for acute myocardial infarction and cardiogenic shock.
Journal: Texas Heart Institute journal 20070101
Title: Rapamycin enhances the anti-tumor effect of gemcitabine in pancreatic cancer cells.
Journal: Hepato-gastroenterology 20070101
Title: [Revascularization of the myocardium in patients with ischemic heart disease. Experience of the use of sirolimus eluting stents].
Journal: Kardiologiia 20070101
Title: [Drug-eluting stent thrombosis and its pharmacological prevention].
Journal: Kardiologiia 20070101
Title: [An experience of the use of stents with drug coating in patients with long and diffuse coronary artery lesions].
Journal: Kardiologiia 20070101
Title: One-sided limb lymphedema in a liver transplant recipient receiving sirolimus.
Journal: Acta gastro-enterologica Belgica 20070101
Title: [Glioblastomas are resistant to apoptosis but less resistant to the autophagic process].
Journal: Bulletin et memoires de l'Academie royale de medecine de Belgique 20070101
Title: [Sirolimus: mechanism of action, use in combined chemotherapy of cancer].
Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20070101
Title: Delayed stent fracture and aneurysm formation after sirolimus eluting stent.
Journal: Indian heart journal 20070101
Title: Pathology of drug-eluting stents: implications for coronary intervention.
Journal: Indian heart journal 20070101
Title: Taxus vs. Cypher: making sense of the 'evidence-based' data.
Journal: Indian heart journal 20070101
Title: Newer stents: looking at the horizon.
Journal: Indian heart journal 20070101
Title: Diabetic multivessel disease: stenting vs. coronary artery bypass grafting.
Journal: Indian heart journal 20070101
Title: Revascularizing diabetics: the CARDia trial.
Journal: Indian heart journal 20070101
Title: Pregnancy outcomes in solid organ transplant recipients with exposure to mycophenolate mofetil or sirolimus.
Journal: Transplantation 20061227
Title: Conversion to sirolimus in renal transplant recipients with skin cancer.
Journal: Transplantation 20061227
Title: Comparative analysis of calcineurin inhibition by complexes of immunosuppressive drugs with human FK506 binding proteins.
Journal: Biochemistry 20061226
Title: Combination treatment of low dose Anti-Thymocyte Globulin (ATG), Rituximab and high dose Sirolimus as induction agents in immune-conditioned recipients.
Journal: International immunopharmacology 20061220
Title: Affects of immunosuppression on circulating dendritic cells: an adjunct to therapeutic drug monitoring after heart transplantation.
Journal: International immunopharmacology 20061220
Title: Reccurence of Kaposi's sarcoma after increased exposure to sirolimus.
Journal: International immunopharmacology 20061220
Title: Randomized double-blind comparison of sirolimus-eluting stent versus bare-metal stent implantation in diseased saphenous vein grafts: six-month angiographic, intravascular ultrasound, and clinical follow-up of the RRISC Trial.
Journal: Journal of the American College of Cardiology 20061219
Title: Comparison of zotarolimus-eluting and sirolimus-eluting stents in patients with native coronary artery disease: a randomized controlled trial.
Journal: Journal of the American College of Cardiology 20061219
Title: Late clinical events after clopidogrel discontinuation may limit the benefit of drug-eluting stents: an observational study of drug-eluting versus bare-metal stents.
Journal: Journal of the American College of Cardiology 20061219
Title: Drug eluting stents.
Journal: BMJ (Clinical research ed.) 20061216
Title: Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20061215
Title: Volumetric intravascular ultrasound assessment of neointimal hyperplasia and nonuniform stent strut distribution in sirolimus-eluting stent restenosis.
Journal: The American journal of cardiology 20061215
Title: Comparison of clinical outcomes of overlapping sirolimus- versus paclitaxel-eluting stents in patients undergoing percutaneous coronary intervention.
Journal: The American journal of cardiology 20061215
Title: Everolimus interferes with healing of experimental intestinal anastomoses.
Journal: Transplantation 20061215
Title: Targeting von Hippel-Lindau pathway in renal cell carcinoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20061215
Title: Translational control via the mammalian target of rapamycin pathway is critical for the formation and stability of long-term fear memory in amygdala neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20061213
Title: Targeted therapy for metastatic renal cell carcinoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061210
Title: Saccharomyces cerevisiae Sit4 phosphatase is active irrespective of the nitrogen source provided, and Gln3 phosphorylation levels become nitrogen source-responsive in a sit4-deleted strain.
Journal: The Journal of biological chemistry 20061208
Title: Drug-eluting stents in primary PCI.
Journal: The New England journal of medicine 20061207
Title: Drug-eluting stents in primary PCI.
Journal: The New England journal of medicine 20061207
Title: Drug-eluting stents in primary PCI.
Journal: The New England journal of medicine 20061207
Title: Rapamycin decreases leukocyte migration in vivo and effectively reduces experimentally induced chronic colitis.
Journal: International journal of colorectal disease 20061201
Title: Sirolimus accelerates senescence of endothelial progenitor cells through telomerase inactivation.
Journal: Atherosclerosis 20061201
Title: Requirement of androgen-dependent activation of protein kinase Czeta for androgen-dependent cell proliferation in LNCaP Cells and its roles in transition to androgen-independent cells.
Journal: Molecular endocrinology (Baltimore, Md.) 20061201
Title: Everolimus drug interactions: application of a classification system for clinical decision making.
Journal: Biopharmaceutics & drug disposition 20061201
Title: Microwave expedited synthesis of 5-aminocamptothecin analogs: Inhibitors of hypoxia inducible factor HIF-1alpha.
Journal: Bioorganic & medicinal chemistry letters 20061201
Title: Rapid chemically induced changes of PtdIns(4,5)P2 gate KCNQ ion channels.
Journal: Science (New York, N.Y.) 20061201
Title: Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling.
Journal: The Journal of biological chemistry 20061201
Title: Helicobacter pylori VacA toxin inhibits human immunodeficiency virus infection of primary human T cells.
Journal: Journal of virology 20061201
Title: Mortality in randomized controlled trials comparing drug-eluting vs. bare metal stents in coronary artery disease: a meta-analysis.
Journal: European heart journal 20061201
Title: Low-dose oral rapamycin treatment reduces fibrogenesis, improves liver function, and prolongs survival in rats with established liver cirrhosis.
Journal: Journal of hepatology 20061201
Title: Comparison of the Innofluor certican assay with HPLC-UV for the determination of everolimus concentrations in heart transplantation.
Journal: Clinical biochemistry 20061201
Title: Differential effects of immunosuppressive drugs on T-cell motility.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20061201
Title: Blocking of Akt/NF-kappaB signaling by pentoxifylline inhibits platelet-derived growth factor-stimulated proliferation in Brown Norway rat airway smooth muscle cells.
Journal: Pediatric research 20061201
Title: Sirolimus as the main immunosuppressant in the early postoperative period following liver transplantation: a report of six cases and review of the literature.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20061201
Title: Sirolimus-eluting stents and calcified coronary lesions: clinical outcomes of patients treated with and without rotational atherectomy.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20061201
Title: Sirolimus pharmacokinetic differences between children and adults.
Journal: Pediatric transplantation 20061201
Title: Sirolimus pharmacokinetics in pediatric renal transplant recipients receiving calcineurin inhibitor co-therapy.
Journal: Pediatric transplantation 20061201
Title: Premature discontinuation of antiplatelet therapy in patients with drug-eluting coronary stents.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20061201
Title: Cypher versus Taxus: the stent war.
Journal: Expert opinion on investigational drugs 20061201
Title: Cause of death with bare metal and sirolimus-eluting stents.
Journal: European heart journal 20061201
Title: Increased mortality after implantation of first generation drug-eluting stents: seeing the smoke, where is the fire?
Journal: European heart journal 20061201
Title: Cost-effectiveness of the unrestricted use of sirolimus-eluting stents vs. bare metal stents at 1 and 2-year follow-up: results from the RESEARCH Registry.
Journal: European heart journal 20061201
Title: Drug-eluting stents and stent thrombosis: a cause for concern?
Journal: Coronary artery disease 20061201
Title: Late stent thrombosis in drug-eluting stents: return of the 'VB syndrome'.
Journal: Nature clinical practice. Cardiovascular medicine 20061201
Title: Drug-eluting stent thrombosis: it's never too late.
Journal: Nature clinical practice. Cardiovascular medicine 20061201
Title: Revascularization of left anterior descending artery with drug-eluting stents: comparison with minimally invasive direct coronary artery bypass surgery.
Journal: The Annals of thoracic surgery 20061201
Title: Comparison with conventional therapies of repeated sirolimus-eluting stent implantation for the treatment of drug-eluting coronary stent restenosis.
Journal: The American journal of cardiology 20061201
Title: Safety and efficacy of the 2.25-mm sirolimus-eluting Bx Velocity stent in the treatment of patients with de novo native coronary artery lesions: the SIRIUS 2.25 trial.
Journal: The American journal of cardiology 20061201
Title: Comparison of the efficacy of direct coronary stenting with sirolimus-eluting stents versus stenting with predilation by intravascular ultrasound imaging (from the DIRECT trial).
Journal: The American journal of cardiology 20061201
Title: Conversion to sirolimus: a useful strategy for recalcitrant cutaneous viral warts in liver transplant recipient.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20061201
Title: Rapamycin-mediated inhibition of mammalian target of rapamycin in skeletal muscle cells reduces glucose utilization and increases fatty acid oxidation.
Journal: Metabolism: clinical and experimental 20061201
Title: Brief review: coronary drug-eluting stents and anesthesia.
Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20061201
Title: Late thrombosis of drug-eluting stents: a meta-analysis of randomized clinical trials.
Journal: The American journal of medicine 20061201
Title: The evolving impact of microfabrication and nanotechnology on stent design.
Journal: Journal of vascular surgery 20061201
Title: Lipid oxidation and autophagy in yeast.
Journal: Free radical biology & medicine 20061201
Title: Targeting the AIB1 oncogene through mammalian target of rapamycin inhibition in the mammary gland.
Journal: Cancer research 20061201
Title: Drug-eluting and bare nitinol stents for the treatment of atherosclerotic lesions in the superficial femoral artery: long-term results from the SIROCCO trial.
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20061201
Title: Comparison of sirolimus-eluting and bare metal stents in coronary bifurcation lesions: subgroup analysis of the Stenting Coronary Arteries in Non-Stress/Benestent Disease Trial (SCANDSTENT).
Journal: American heart journal 20061201
Title: Predictors of death or myocardial infarction during follow-up after coronary stenting with the sirolimus-eluting stent. Results from the prospective multicenter German Cypher Stent Registry.
Journal: American heart journal 20061201
Title: Angioscopic evaluation of neointima coverage: sirolimus drug-eluting stent versus bare metal stent.
Journal: American heart journal 20061201
Title: The role of therapeutic drug monitoring in individualizing immunosuppressive drug therapy: recent developments.
Journal: Therapeutic drug monitoring 20061201
Title: 12-hour area under the curve cyclosporine concentrations determined by a validated liquid chromatography-mass spectrometry procedure compared with fluorescence polarization immunoassay reveals sirolimus effect on cyclosporine pharmacokinetics.
Journal: Therapeutic drug monitoring 20061201
Title: [The role of caspase-3 in rapamycin-induced apoptosis of hepatocellular carcinoma BEL-7402 cells].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20061201
Title: Farnesyltransferase inhibitors and rapamycin in the treatment of multiple myeloma.
Journal: Current pharmaceutical biotechnology 20061201
Title: Plumbagin induces G2-M arrest and autophagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells.
Journal: Molecular cancer therapeutics 20061201
Title: Changes in abdominal wounds following treatment with sirolimus and steroids in a rat model.
Journal: Transplantation proceedings 20061201
Title: Differential pharmacokinetic interaction of tacrolimus and cyclosporine on everolimus.
Journal: Transplantation proceedings 20061201
Title: Short-term results under three different immunosuppressive regimens at one center.
Journal: Transplantation proceedings 20061201
Title: Results of a calcineurin-inhibitor-free immunosuppressive protocol in renal transplant recipients of expanded criteria deceased donors.
Journal: Transplantation proceedings 20061201
Title: Sirolimus attenuates the rate of progression of early chronic allograft nephropathy.
Journal: Transplantation proceedings 20061201
Title: Proteinuria after conversion to sirolimus in renal transplant recipients.
Journal: Transplantation proceedings 20061201
Title: Post-rapamycin proteinuria: incidence, evolution, and therapeutic handling at a single center.
Journal: Transplantation proceedings 20061201
Title: Exposure-efficacy relationships of a fingolimod-everolimus regimen in kidney transplant patients at risk for delayed graft function.
Journal: Transplantation proceedings 20061201
Title: Risk factors for wound healing complications in sirolimus-treated renal transplant recipients.
Journal: Transplantation proceedings 20061201
Title: Characteristics of neoplasm occurrence and the therapeutic effect of sirolimus in South Chinese kidney transplant recipients.
Journal: Transplantation proceedings 20061201
Title: Predictors of decline in renal function after lung transplantation.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20061201
Title: Molecularly targeted therapy in renal cell carcinoma: where do we go from here?
Journal: Expert review of anticancer therapy 20061201
Title: Targeted therapies in metastatic renal cell carcinoma: the light at the end of the tunnel.
Journal: Expert review of anticancer therapy 20061201
Title: Effects of sirolimus on proteinuria and renal function in focal segmental glomerulonephritis.
Journal: International journal of clinical pharmacology and therapeutics 20061201
Title: Successful mobilization of peripheral blood stem cells by use of granulocyte-colony stimulating factor and their transcoronary transplantation in a patient after cardiogenic shock due to acute myocardial infarction.
Journal: The Journal of invasive cardiology 20061201
Title: Late stent thrombosis mimicking focal restenosis after sirolimus stent implantation: angiographic and intravascular ultrasound appraisal.
Journal: The Journal of invasive cardiology 20061201
Title: [Pulmonary toxicity associated with sirolimus therapy in liver transplantation].
Journal: Gastroenterologia y hepatologia 20061201
Title: Apparent clearance of sirolimus in heart transplant recipients: impact of primary diagnosis and serum lipids.
Journal: Therapeutic drug monitoring 20061201
Title: Effects of tacrolimus or sirolimus on proliferation of vascular smooth muscle and endothelial cells.
Journal: Journal of cardiovascular pharmacology 20061201
Title: Temporal decline in sirolimus elimination immediately after pancreatic islet transplantation.
Journal: Drug metabolism and pharmacokinetics 20061201
Title: Renal function and histology in kidney transplant patients receiving tacrolimus and sirolimus or mycophenolate mofetil.
Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20061201
Title: [Initial and mid-term effects of > or = 30 mm long sirolimus-eluting stents in patients with diffuse long coronary lesions: comparison with bare metal stents].
Journal: Journal of cardiology 20061201
Title: The growing role of mTOR in neuronal development and plasticity.
Journal: Molecular neurobiology 20061201
Title: [The clinical efficacy of sirolimus-eluting stents versus paclitaxel-eluting stents in complex and diffuse coronary lesions].
Journal: Zhonghua nei ke za zhi 20061201
Title: Effect of rapamycin on the fate of P23H opsin associated with retinitis pigmentosa (an American Ophthalmological Society thesis).
Journal: Transactions of the American Ophthalmological Society 20061201
Title: The influence of copolymer chain microstructure on cyclosporine a (CyA) and Sirolimus prolonged and sustained release from PLA/TMC and PLA/PCL matrices.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20061128
Title: Use of the organotypic culture method to investigate drug-loaded CSF shunt.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20061128
Title: Ethoxyethyl methacrylate-based copolymers--a novel platform for drug-eluting stent coatings.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20061128
Title: Generating rapamycin analogues by directed biosynthesis: starter acid substrate specificity of mono-substituted cyclohexane carboxylic acids.
Journal: Organic & biomolecular chemistry 20061121
Title: Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin.
Journal: Blood 20061115
Title: Conversion from calcineurin inhibitors to sirolimus for chronic renal allograft dysfunction: a systematic review of the evidence.
Journal: Transplantation 20061115
Title: Combined transcriptional and translational targeting of EWS/FLI-1 in Ewing's sarcoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20061115
Title: Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20061115
Title: Early- and medium-term outcomes after paclitaxel-eluting stent implantation for sirolimus-eluting stent failure.
Journal: The American journal of cardiology 20061115
Title: Outcomes of 6906 patients undergoing percutaneous coronary intervention in the era of drug-eluting stents: report of the DEScover Registry.
Journal: Circulation 20061114
Title: Sirolimus-eluting stent versus paclitaxel-eluting stent for patients with long coronary artery disease.
Journal: Circulation 20061114
Title: Images in cardiovascular medicine. Damage to polymer of a sirolimus-eluting stent.
Journal: Circulation 20061114
Title: Recurrent restenosis in a patient with cardiac allograft vasculopathy: after angioplasty and sirolimus, paclitaxel saves the day.
Journal: International journal of cardiology 20061110
Title: Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways.
Journal: Oncogene 20061109
Title: Trading restenosis for thrombosis? New questions about drug-eluting stents.
Journal: The New England journal of medicine 20061109
Title: Connecting the dots using gene-expression profiles.
Journal: The New England journal of medicine 20061109
Title: A phase II clinical and pharmacodynamic study of temsirolimus in advanced neuroendocrine carcinomas.
Journal: British journal of cancer 20061106
Title: Modulation of collagen and MMP-1 gene expression in fibroblasts by the immunosuppressive drug rapamycin. A direct role as an antifibrotic agent?
Journal: The Journal of biological chemistry 20061103
Title: Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils.
Journal: Oncogene 20061102
Title: Safety, tolerability, and efficacy of everolimus in de novo liver transplant recipients: 12- and 36-month results.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20061101
Title: Regression of post-transplant Kaposi's sarcoma using sirolimus.
Journal: International journal of clinical practice 20061101
Title: Inclusion of MPA and in a rapid multi-drug LC-tandem mass spectrometric method for simultaneous determination of immunosuppressants.
Journal: Clinica chimica acta; international journal of clinical chemistry 20061101
Title: Controlled release of sirolimus from a multilayered PLGA stent matrix.
Journal: Biomaterials 20061101
Title: A downstream kinase of the mammalian target of rapamycin, p70S6K1, regulates human double minute 2 protein phosphorylation and stability.
Journal: Journal of cellular physiology 20061101
Title: Use of a stringent dimerizer-regulated gene expression system for controlled BMP2 delivery.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20061101
Title: Cyclosporine withdrawal improves renal function in heart transplant patients on reduced-dose cyclosporine therapy.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20061101
Title: Effects of rapamycin on accumulation of alpha-, beta- and gamma-globin mRNAs in erythroid precursor cells from beta-thalassaemia patients.
Journal: European journal of haematology 20061101
Title: Increase of proteinuria after conversion from calcineurin inhibitor to sirolimus-based treatment in kidney transplant patients with chronic allograft dysfunction.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20061101
Title: The immunosuppressant rapamycin exacerbates neurotoxicity of Abeta peptide.
Journal: Journal of neuroscience research 20061101
Title: Nitrogen availability and TOR regulate the Snf1 protein kinase in Saccharomyces cerevisiae.
Journal: Eukaryotic cell 20061101
Title: Antiangiogenic and immunomodulatory effects of rapamycin on islet endothelium: relevance for islet transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20061101
Title: PTEN in the haematopoietic system and its therapeutic indications.
Journal: Trends in molecular medicine 20061101
Title: The role of heme oxygenase 1 in rapamycin-induced renal dysfunction after ischemia and reperfusion injury.
Journal: Kidney international 20061101
Title: Outcomes at 3 years of a prospective pilot study of Campath-1H and sirolimus immunosuppression for renal transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20061101
Title: Outcome in the real-world of coronary high-risk intervention with drug-eluting stents (ORCHID) -- a single-center study comparing Cypher sirolimus-eluting with Taxus paclitaxel-eluting stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20061101
Title: Randomized trial versus registry data--comparing apples and ORCHIDs.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20061101
Title: Stent thrombosis following the STAR technique in a complex RCA chronic total occlusion.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20061101
Title: Sirolimus for below the knee lesions: mid-term results of SiroBTK study.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20061101
Title: Surfactant as a carrier: influence of immunosuppressive agents on surfactant activity.
Journal: Clinical physiology and functional imaging 20061101
Title: Chemotherapy disrupts activity of translational regulatory proteins in bone marrow stromal cells.
Journal: Experimental hematology 20061101
Title: Risk of noncardiac surgery after coronary drug-eluting stent implantation.
Journal: The American journal of cardiology 20061101
Title: Inflammatory response to drug-eluting stent placement.
Journal: The American journal of cardiology 20061101
Title: Everolimus and mTOR inhibitors in liver transplantation: opening the 'box'.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20061101
Title: Clinical and angiographic outcomes of sirolimus-eluting stents implantation in Japanese patients in daily practice.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20061101
Title: Persistent malapposition after implantation of sirolimus-eluting stent into intramural coronary hematoma: optical coherence tomography observations.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20061101
Title: Drug-eluting stents in total coronary occlusions: another piece of the puzzle solved?
Journal: American heart journal 20061101
Title: Sirolimus versus bare metal stent implantation in patients with total coronary occlusions: subgroup analysis of the Stenting Coronary Arteries in Non-Stress/Benestent Disease (SCANDSTENT) trial.
Journal: American heart journal 20061101
Title: Single-vessel versus bifurcation stenting for the treatment of distal left main coronary artery disease in the drug-eluting stenting era. Clinical and angiographic insights into the Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) and Taxus-Stent Evaluated at Rotterdam Cardiology Hospital (T-SEARCH) registries.
Journal: American heart journal 20061101
Title: Comparison between drug-eluting stents and beta-radiation for the treatment of diffuse in-stent restenosis: clinical and angiographic outcomes.
Journal: American heart journal 20061101
Title: Progressive stent technologies: new approaches for the treatment of cardiovascular diseases.
Journal: Expert opinion on drug delivery 20061101
Title: Critics say drug-eluting stents overused.
Journal: JAMA 20061101
Title: Use of sirolimus for Epstein-Barr virus-positive smooth-muscle tumour.
Journal: The Lancet. Oncology 20061101
Title: Should the left main be covered entirely with drug-eluting stents in percutaneous intervention.
Journal: The Journal of invasive cardiology 20061101
Title: Incomplete stent apposition in a left main bifurcated lesion after kissing stent implantation.
Journal: The Journal of invasive cardiology 20061101
Title: Protein kinases as drug targets in cancer.
Journal: Current cancer drug targets 20061101
Title: Use of sirolimus to facilitate steroid withdrawal from a cyclosporine regimen.
Journal: Transplantation proceedings 20061101
Title: Initial single-center experience with sirolimus after lung transplantation.
Journal: Transplantation proceedings 20061101
Title: A monoselective sphingosine-1-phosphate receptor-1 agonist prevents allograft rejection in a stringent rat heart transplantation model.
Journal: Chemistry & biology 20061101
Title: Dissecting the mechanism of T-cell anergy with immunophilin ligands.
Journal: Current opinion in investigational drugs (London, England : 2000) 20061101
Title: Rapamycin synergizes with the epidermal growth factor receptor inhibitor erlotinib in non-small-cell lung, pancreatic, colon, and breast tumors.
Journal: Molecular cancer therapeutics 20061101
Title: Drug-eluting stents--safety concerns.
Journal: Clinical cardiology 20061101
Title: [Promising efficacy of the sirolimus-eluting stent in patients with acute myocardial infarction].
Journal: Journal of cardiology 20061101
Title: [Update on clinical activity of CCI779 (temsirolimus), mTOR inhibitor].
Journal: Bulletin du cancer 20061101
Title: Case report: sirolimus associated interstitial lung disease.
Journal: South Dakota medicine : the journal of the South Dakota State Medical Association 20061101
Title: Late outcome of sirolimus-eluting stents: comparison of multidetector computed tomography with quantitative coronary angiography and intravascular ultrasound.
Journal: Arquivos brasileiros de cardiologia 20061101
Title: Very late stent thrombosis after implantation of drug eluting stent.
Journal: The Journal of the Association of Physicians of India 20061101
Title: BioMatrix Biolimus A9-eluting coronary stent: a next-generation drug-eluting stent for coronary artery disease.
Journal: Expert review of medical devices 20061101
Title: [Safety and efficacy comparison between rapamycin-eluting stent with biodegradable polymer or permanent polymer in patients with coronary artery disease].
Journal: Zhonghua xin xue guan bing za zhi 20061101
Title: [Sirolimus inhibits the differentiation, proliferation and migration of endothelial progenitor cells in vitro].
Journal: Zhonghua xin xue guan bing za zhi 20061101
Title: Beyond imatinib: second generation c-KIT inhibitors for the management of gastrointestinal stromal tumors.
Journal: Clinical colorectal cancer 20061101
Title: Randomized study on simple versus complex stenting of coronary artery bifurcation lesions: the Nordic bifurcation study.
Journal: Circulation 20061031
Title: [Drug-eluting coronary stents].
Journal: Orvosi hetilap 20061029
Title: Images in cardiovascular medicine. Hypertrophic obstructive cardiomyopathy: septal ablation with overlapping sirolimus-eluting and covered stents after failed alcoholization and concomitant coronary artery disease.
Journal: Circulation 20061024
Title: Predicted mechanisms of resistance to mTOR inhibitors.
Journal: British journal of cancer 20061023
Title: Sirolimus-eluting stents vs brachytherapy for restenosis.
Journal: JAMA 20061018
Title: [Administration of sirolimus affects vein graft neointima hyperplasia].
Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20061018
Title: Unprotected left main disease: stent or surgery?
Journal: Journal of the American College of Cardiology 20061017
Title: mTOR and cancer therapy.
Journal: Oncogene 20061016
Title: Effect of plaque volume on subsequent vessel remodeling at edges of sirolimus-eluting stents.
Journal: The American journal of cardiology 20061015
Title: Sirolimus interferes with iron homeostasis in renal transplant recipients.
Journal: Transplantation 20061015
Title: Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells.
Journal: Cancer research 20061015
Title: Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling.
Journal: Oncogene 20061012
Title: Switch from cyclosporine to sirolimus as a treatment of acute renal failure complicating cardiogenic shock in a heart transplant recipient.
Journal: International journal of cardiology 20061010
Title: Rapamycin biosynthesis: Elucidation of gene product function.
Journal: Organic & biomolecular chemistry 20061007
Title: Activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites.
Journal: Science (New York, N.Y.) 20061006
Title: Vessel size and outcome after coronary drug-eluting stent placement: results from a large cohort of patients treated with sirolimus- or paclitaxel-eluting stents.
Journal: Journal of the American College of Cardiology 20061003
Title: All drug-eluting stents are equal, but some drug-eluting stents are more equal than others.
Journal: Journal of the American College of Cardiology 20061003
Title: Clinical outcomes for sirolimus-eluting stents and polymer-coated paclitaxel-eluting stents in daily practice: results from a large multicenter registry.
Journal: Journal of the American College of Cardiology 20061003
Title: Citrus auraptene targets translation of MMP-7 (matrilysin) via ERK1/2-dependent and mTOR-independent mechanism.
Journal: FEBS letters 20061002
Title: Recurrence of proteinuria 10 years post-transplant in NPHS2-associated focal segmental glomerulosclerosis after conversion from cyclosporin A to sirolimus.
Journal: Pediatric nephrology (Berlin, Germany) 20061001
Title: Mammalian target of rapamycin regulates the growth of mammary epithelial cells through the inhibitor of deoxyribonucleic acid binding Id1 and their functional differentiation through Id2.
Journal: Molecular endocrinology (Baltimore, Md.) 20061001
Title: Combination of a rapamycin analog (CCI-779) and interferon-gamma is more effective than single agents in treating a mouse model of tuberous sclerosis complex.
Journal: Genes, chromosomes & cancer 20061001
Title: Everolimus inhibits glomerular endothelial cell proliferation and VEGF, but not long-term recovery in experimental thrombotic microangiopathy.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20061001
Title: Registry data evaluating the effectiveness of drug-eluting stents for the treatment of symptomatic in-stent restenosis.
Journal: Heart, lung & circulation 20061001
Title: The impact of the mTOR inhibitor sirolimus on the proliferation and function of pancreatic islets and ductal cells.
Journal: Diabetologia 20061001
Title: Proteinuria following conversion from azathioprine to sirolimus in renal transplant recipients.
Journal: Kidney international 20061001
Title: The proangiogenic phenotype of human tumor-derived endothelial cells depends on thrombospondin-1 downregulation via phosphatidylinositol 3-kinase/Akt pathway.
Journal: Journal of molecular medicine (Berlin, Germany) 20061001
Title: Patterns of restenosis after drug-eluting stent implantation: Insights from a contemporary and comparative analysis of sirolimus- and paclitaxel-eluting stents.
Journal: European heart journal 20061001
Title: Calcineurin-inhibitor induced pain syndrome after organ transplantation.
Journal: Kidney international 20061001
Title: Safety, feasibility, and short-term follow-up of drug-eluting stent placement in the intracranial and extracranial circulation.
Journal: Stroke 20061001
Title: Effect of rapamycin on renal ischemia-reperfusion injury in mice.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20061001
Title: Sirolimus monotherapy versus sirolimus in combination with steroids and/or MMF for immunosuppression after liver transplantation.
Journal: Digestive diseases and sciences 20061001
Title: Investigating mammalian target of rapamycin inhibitors for their anticancer properties.
Journal: Expert opinion on investigational drugs 20061001
Title: A Bayesian approach for population pharmacokinetic modelling of sirolimus.
Journal: British journal of clinical pharmacology 20061001
Title: A comparison of the effect of ciclosporin and sirolimus on the pharmokinetics of mycophenolate in renal transplant patients.
Journal: British journal of clinical pharmacology 20061001
Title: Three-year clinical follow-up of the unrestricted use of sirolimus-eluting stents as part of the Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry.
Journal: The American journal of cardiology 20061001
Title: Clinical and angiographic outcomes after placement of multiple overlapping drug-eluting stents in diffuse coronary lesions.
Journal: The American journal of cardiology 20061001
Title: Monomorphic Epstein-Barr virus (EBV)-associated large B-cell posttransplant lymphoproliferative disorder presenting as a tongue ulcer in a pancreatic transplant patient.
Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20061001
Title: Mycophenolate mofetil versus sirolimus as an adjunct to calcineurin inhibition after renal transplantation.
Journal: Nature clinical practice. Nephrology 20061001
Title: Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance.
Journal: Cancer cell 20061001
Title: Sirolimus monotherapy for Kaposi's sarcoma in an HIV-negative patient.
Journal: The Lancet. Oncology 20061001
Title: Autophagy in cancer: good, bad, or both?
Journal: Cancer research 20061001
Title: Ras-induced modulation of CXCL10 and its receptor splice variant CXCR3-B in MDA-MB-435 and MCF-7 cells: relevance for the development of human breast cancer.
Journal: Cancer research 20061001
Title: Clinical evidence on polymer-based sirolimus and paclitaxel eluting stents.
Journal: Minerva cardioangiologica 20061001
Title: How to treat diabetic patients with multivesseal disease in the DES era.
Journal: Minerva cardioangiologica 20061001
Title: Overview of pharmacology and clinical trials program with the zotarolimus-eluting endeavor stent.
Journal: Journal of interventional cardiology 20061001
Title: A phase I and pharmacokinetic study of temsirolimus (CCI-779) administered intravenously daily for 5 days every 2 weeks to patients with advanced cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20061001
Title: Role of the Fusarium fujikuroi TOR kinase in nitrogen regulation and secondary metabolism.
Journal: Eukaryotic cell 20061001
Title: A temporal switch in the insulin-signalling pathway that regulates hepatic IGF-binding protein-1 gene expression.
Journal: Journal of molecular endocrinology 20061001
Title: Sirolimus--challenging current perspectives.
Journal: Therapeutic drug monitoring 20061001
Title: Apparent clearance of sirolimus in heart transplant recipients: impact of primary diagnosis and serum lipids.
Journal: Therapeutic drug monitoring 20061001
Title: Safety and pharmacokinetics of sirolimus-eluting stents in the canine cerebral vasculature: 180 day assessment.
Journal: Neurosurgery 20061001
Title: Signaling interactions of rapamycin combined with erlotinib in cervical carcinoma xenografts.
Journal: Molecular cancer therapeutics 20061001
Title: The antitumor effects of sunitinib (formerly SU11248) against a variety of human hematologic malignancies: enhancement of growth inhibition via inhibition of mammalian target of rapamycin signaling.
Journal: Molecular cancer therapeutics 20061001
Title: Balloon alignment T-stenting for bifurcation coronary artery disease using the sirolimus-eluting stent.
Journal: The Journal of invasive cardiology 20061001
Title: Sirolimus-eluting stenting of the external carotid artery for the treatment of ocular ischemia.
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20061001
Title: Iliac anastomotic stenting with a sirolimus-eluting biodegradable poly-L-lactide stent: a preliminary study after 6 weeks.
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20061001
Title: Molecular biology of renal cell carcinoma.
Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20061001
Title: Mammalian target of rapamycin inhibitors in combination with letrozole in breast cancer.
Journal: Clinical breast cancer 20061001
Title: Calcineurin inhibitors affect circulating regulatory T cells in stable renal transplant recipients.
Journal: Transplantation proceedings 20061001
Title: Conversion to everolimus in kidney transplant recipients: a safe and simple procedure.
Journal: Transplantation proceedings 20061001
Title: Pulmonary toxicity associated with sirolimus treatment in kidney transplantation.
Journal: Transplantation proceedings 20061001
Title: Conversion to sirolimus in renal transplant patients with tumors.
Journal: Transplantation proceedings 20061001
Title: Conversion from calcineurin inhibitors to everolimus in kidney transplant recipients with malignant neoplasia.
Journal: Transplantation proceedings 20061001
Title: Sirolimus experience in heart transplantation.
Journal: Transplantation proceedings 20061001
Title: Sirolimus attenuates chronic allograft nephropathy in an experimental rat kidney transplantation model.
Journal: Transplantation proceedings 20061001
Title: [Efficacy of sirolimus-eluting stent implantation in diabetic patients with very small vessels (< or = 2.25 mm). Insights from the DIABETES trial].
Journal: Revista espanola de cardiologia 20061001
Title: Living donor islet transplantation, the alternative approach to overcome the obstacles limiting transplant.
Journal: Annals of the New York Academy of Sciences 20061001
Title: Direct versus predilatation drug-eluting stenting: a randomized clinical trial.
Journal: The Journal of invasive cardiology 20061001
Title: Generation of HSP60-specific regulatory T cell and effect on atherosclerosis.
Journal: Cellular immunology 20061001
Title: The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.
Journal: Science (New York, N.Y.) 20060929
Title: Rapamycin and dendritic cells: keep on movin'.
Journal: Transplantation 20060927
Title: Development of de novo cancer in p53 knock-out mice is dependent on the type of long-term immunosuppression used.
Journal: Transplantation 20060927
Title: Differential effects of immunosuppressive drugs on chemokine receptor CCR7 in human monocyte-derived dendritic cells: selective upregulation by rapamycin.
Journal: Transplantation 20060927
Title: mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s.
Journal: Current biology : CB 20060919
Title: Human cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexes.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20060919
Title: Characterization of plaque prolapse after drug-eluting stent implantation in diabetic patients: a three-dimensional volumetric intravascular ultrasound outcome study.
Journal: Journal of the American College of Cardiology 20060919
Title: Rapamycin improves lymphoproliferative disease in murine autoimmune lymphoproliferative syndrome (ALPS).
Journal: Blood 20060915
Title: Comparison of outcomes between bare metal stents and drug-eluting stents for percutaneous revascularization of internal mammary grafts.
Journal: The American journal of cardiology 20060915
Title: Acute renal failure following kidney transplantation associated with myoglobinuria in patients treated with rapamycin.
Journal: Transplantation 20060915
Title: Sirolimus-eluting versus uncoated stents in acute myocardial infarction.
Journal: The New England journal of medicine 20060914
Title: Drug-eluting stents in acute myocardial infarction.
Journal: The New England journal of medicine 20060914
Title: Release of anti-restenosis drugs from poly(ethylene oxide)-poly(DL-lactic-co-glycolic acid) nanoparticles.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20060912
Title: Inhibition of mammalian target of rapamycin modulates expression of adhesion molecules in endothelial cells.
Journal: Toxicology letters 20060910
Title: Targeting protein stability with a small molecule.
Journal: Cell 20060908
Title: Mind the GAP: Wnt steps onto the mTORC1 train.
Journal: Cell 20060908
Title: TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth.
Journal: Cell 20060908
Title: Three new drugs available to fight kidney cancer.
Journal: Journal of the National Cancer Institute 20060906
Title: Cyclosporin A, tacrolimus and sirolimus are potent inhibitors of the human breast cancer resistance protein (ABCG2) and reverse resistance to mitoxantrone and topotecan.
Journal: Cancer chemotherapy and pharmacology 20060901
Title: Leucine in food mediates some of the postprandial rise in plasma leptin concentrations.
Journal: American journal of physiology. Endocrinology and metabolism 20060901
Title: Fibroblasts isolated from human pterygia exhibit altered lipid metabolism characteristics.
Journal: Experimental eye research 20060901
Title: Co-administration of sirolimus alters tacrolimus pharmacokinetics in a dose-dependent manner in adult renal transplant recipients.
Journal: Pharmacological research 20060901
Title: Sirolimus conversion for patients with posttransplant Kaposi's sarcoma.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060901
Title: mTOR inhibition induces endothelial progenitor cell death.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060901
Title: Rheb inhibits C-raf activity and B-raf/C-raf heterodimerization.
Journal: The Journal of biological chemistry 20060901
Title: Prolongation of allograft survival by administration of anti-CD45RB monoclonal antibody is due to alteration of CD45RBhi: CD45RBlo T-cell proportions.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060901
Title: Role of P-glycoprotein in cyclosporine cytotoxicity in the cyclosporine-sirolimus interaction.
Journal: Kidney international 20060901
Title: ['HAART-attack' in young female HIV-patient].
Journal: Der Internist 20060901
Title: Effect of sirolimus in the prevention of adhesions around intraabdominal prosthetic graft.
Journal: World journal of surgery 20060901
Title: Mammalian target of rapamycin inhibition induces cell cycle arrest in diffuse large B cell lymphoma (DLBCL) cells and sensitises DLBCL cells to rituximab.
Journal: British journal of haematology 20060901
Title: The place of sirolimus in kidney transplantation: can we reduce calcineurin inhibitor renal toxicity?
Journal: Kidney international 20060901
Title: Akt and Mammalian target of rapamycin regulate separate systems of proteolysis in renal tubular cells.
Journal: Journal of the American Society of Nephrology : JASN 20060901
Title: Improved survival with drug-eluting stent implantation in comparison with bare metal stent in patients with severe left ventricular dysfunction.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060901
Title: Very late [corrected] thrombosis of a sirolimus-eluting stent.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060901
Title: The role of BMS in the drug eluting stent era: is still there any place for them?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060901
Title: Angioscopic differences in neointimal coverage and in persistence of thrombus between sirolimus-eluting stents and bare metal stents after a 6-month implantation.
Journal: European heart journal 20060901
Title: Rapamycin induces regression of endometriotic lesions by inhibiting neovascularization and cell proliferation.
Journal: British journal of pharmacology 20060901
Title: Delayed neointimal healing after drug-eluting stent implantation: seeing is believing.
Journal: European heart journal 20060901
Title: New treatment approaches in metastatic renal cell carcinoma.
Journal: Current opinion in urology 20060901
Title: Treatment strategies in pediatric solid organ transplant recipients with calcineurin inhibitor-induced nephrotoxicity.
Journal: Pediatric transplantation 20060901
Title: Amiodarone-sirolimus/tacrolimus interaction in a pediatric heart transplant patient.
Journal: Pediatric transplantation 20060901
Title: Effect of SU11248 on gastrointestinal stromal tumor-T1 cells: enhancement of growth inhibition via inhibition of 3-kinase/Akt/mammalian target of rapamycin signaling.
Journal: Cancer science 20060901
Title: Ex vivo rapamycin generates Th1/Tc1 or Th2/Tc2 Effector T cells with enhanced in vivo function and differential sensitivity to post-transplant rapamycin therapy.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20060901
Title: Relation of C-reactive protein level and long-term risk of death or myocardial infarction following percutaneous coronary intervention with a sirolimus-eluting stent.
Journal: The American journal of cardiology 20060901
Title: Investigating the caffeine effects in the yeast Saccharomyces cerevisiae brings new insights into the connection between TOR, PKC and Ras/cAMP signalling pathways.
Journal: Molecular microbiology 20060901
Title: Mycophenolate mofetil and sirolimus combination in renal transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060901
Title: Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20060901
Title: Sirolimus is associated with reduced islet engraftment and impaired beta-cell function.
Journal: Diabetes 20060901
Title: Constitutive phosphorylation of the S6 ribosomal protein via mTOR and ERK signaling in the peripheral blasts of acute leukemia patients.
Journal: Experimental hematology 20060901
Title: Rapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus.
Journal: Arthritis and rheumatism 20060901
Title: [Effect of rapamycin and dexamethasone on differentiation and maturation of murine bone marrow-derived dendritic cells].
Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20060901
Title: Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060901
Title: Natural Products in Drug Discovery & Development II--2nd annual Taylor & Francis conference. 21-22 June 2006, London, UK.
Journal: IDrugs : the investigational drugs journal 20060901
Title: Drug evaluation: AP-23573--an mTOR inhibitor for the treatment of cancer.
Journal: IDrugs : the investigational drugs journal 20060901
Title: Combination therapy for treating breast cancer using antiestrogen, ERA-923, and the mammalian target of rapamycin inhibitor, temsirolimus.
Journal: Endocrine-related cancer 20060901
Title: Sirolimus-associated interstitial pneumonitis in 3 heart transplant recipients.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060901
Title: [Nephrotoxicity of sirolimus: experimental and clinical data].
Journal: Nephrologie & therapeutique 20060901
Title: Therapeutic targets: MTOR and related pathways.
Journal: Cancer biology & therapy 20060901
Title: Influence of everolimus on cyclosporine Neoral pharmacokinetics in Chinese de novo cardiac transplant recipients.
Journal: Transplantation proceedings 20060901
Title: Therapeutic drug monitoring of cyclosporine Neoral in de novo Chinese cardiac transplant recipients treated with an everolimus-cyclosporine immunosuppressive regimen.
Journal: Transplantation proceedings 20060901
Title: Comparison of rapamycin versus FK506 on expression of cytoprotective genes in the rat kidney allografts undergoing chronic allograft nephropathy.
Journal: Transplantation proceedings 20060901
Title: Evaluation of an immunoassay (Abbott-IMX Analyzer) allowing routine determination of sirolimus: comparison with LC-MS method.
Journal: Transplantation proceedings 20060901
Title: Phosphatidylinositol 3-kinase/Akt plays a part in tumor necrosis factor-alpha-induced interleukin-6 synthesis in osteoblasts.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20060901
Title: Cyclin D3 is down-regulated by rapamycin in HER-2-overexpressing breast cancer cells.
Journal: Molecular cancer therapeutics 20060901
Title: Aging and immortality: quasi-programmed senescence and its pharmacologic inhibition.
Journal: Cell cycle (Georgetown, Tex.) 20060901
Title: Use of APO2L/TRAIL with mTOR inhibitors in the treatment of glioblastoma multiforme.
Journal: Expert review of anticancer therapy 20060901
Title: Stenting of unprotected left main coronary artery in patients with low preoperative risk of coronary artery bypass grafting.
Journal: Kardiologia polska 20060901
Title: Effectiveness of a sirolimus-eluting stent (Cypher) for diffuse in-stent restenosis inside a bare metal stent.
Journal: International heart journal 20060901
Title: Late angiographic stent thrombosis in a drug-eluting stent that occurred 20 months after premature discontinuation of clopidogrel administration.
Journal: International heart journal 20060901
Title: Revascularization of malignant coronary instent restenosis resulting from Takayasu's arteritis using sirolimus-eluting stents.
Journal: International heart journal 20060901
Title: The Akt/mTOR and mitogen-activated protein kinase pathways in lung cancer therapy.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20060901
Title: Steroid sparing in kidney transplantation: changing paradigms, improving outcomes, and remaining questions.
Journal: Clinical journal of the American Society of Nephrology : CJASN 20060901
Title: Sirolimus therapy following early cyclosporine withdrawal in transplant patients: mechanisms of action and clinical results.
Journal: International journal of nanomedicine 20060901
Title: Current status of clinical trials for glioblastoma.
Journal: Reviews on recent clinical trials 20060901
Title: Nutrient regulates Tor1 nuclear localization and association with rDNA promoter.
Journal: Nature 20060831
Title: Primary Stenting of Totally Occluded Native Coronary Arteries II (PRISON II): a randomized comparison of bare metal stent implantation with sirolimus-eluting stent implantation for the treatment of total coronary occlusions.
Journal: Circulation 20060829
Title: The FRB domain of mTOR: NMR solution structure and inhibitor design.
Journal: Biochemistry 20060829
Title: Tacrolimus and sirolimus cause insulin resistance in normal sprague dawley rats.
Journal: Transplantation 20060827
Title: Calcineurin inhibitors, but not rapamycin, reduce percentages of CD4+CD25+FOXP3+ regulatory T cells in renal transplant recipients.
Journal: Transplantation 20060827
Title: TOR regulates late steps of ribosome maturation in the nucleoplasm via Nog1 in response to nutrients.
Journal: The EMBO journal 20060823
Title: Randomized, double-blind, multicenter study of the Endeavor zotarolimus-eluting phosphorylcholine-encapsulated stent for treatment of native coronary artery lesions: clinical and angiographic results of the ENDEAVOR II trial.
Journal: Circulation 20060822
Title: Letter by Tsai et al regarding article, 'correlates and long-term outcomes of angiographically proven stent thrombosis with sirolimus- and Paclitaxel-eluting stents'.
Journal: Circulation 20060822
Title: PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR.
Journal: Nature 20060817
Title: A developmental transition in growth control during zebrafish caudal fin development.
Journal: Developmental biology 20060815
Title: Outcome after acute incomplete sirolimus-eluting stent apposition as assessed by serial intravascular ultrasound.
Journal: The American journal of cardiology 20060815
Title: Angiographic results of the first human experience with the Biolimus A9 drug-eluting stent for de novo coronary lesions.
Journal: The American journal of cardiology 20060815
Title: Effect of everolimus-eluting stents in different vessel sizes (from the pooled FUTURE I and II trials).
Journal: The American journal of cardiology 20060815
Title: Differences in proteinuria and graft function in de novo sirolimus-based vs. calcineurin inhibitor-based immunosuppression in live donor kidney transplantation.
Journal: Transplantation 20060815
Title: Delayed gastric ulcer healing associated with sirolimus.
Journal: Transplantation 20060815
Title: Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells.
Journal: Cancer research 20060815
Title: Patency of the left coronary artery by 64-slice multislice computed tomography following implantation of sirolimus-eluting stent.
Journal: International journal of cardiology 20060810
Title: Rapamycin activates Tap42-associated phosphatases by abrogating their association with Tor complex 1.
Journal: The EMBO journal 20060809
Title: Spatial memory formation and memory-enhancing effect of glucose involves activation of the tuberous sclerosis complex-Mammalian target of rapamycin pathway.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060802
Title: Effects of a combined treatment with mTOR inhibitor RAD001 and tamoxifen in vitro on growth and apoptosis of human cancer cells.
Journal: Gynecologic oncology 20060801
Title: Neointimal proliferation around malapposed struts of a sirolimus-eluting stent: optical coherence tomography findings.
Journal: European heart journal 20060801
Title: Switching immunosuppression medications after renal transplantation--a common practice.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801
Title: Rapamycin inhibits growth and survival of D816V-mutated c-kit mast cells.
Journal: Blood 20060801
Title: Hypoxia-inducible factor-1-dependent and -independent regulation of insulin-like growth factor-1-stimulated vascular endothelial growth factor secretion.
Journal: The Journal of pharmacology and experimental therapeutics 20060801
Title: Nephrotoxicity of ciclosporin A: short-term gain, long-term pain?
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801
Title: Rapamycin confers preconditioning-like protection against ischemia-reperfusion injury in isolated mouse heart and cardiomyocytes.
Journal: Journal of molecular and cellular cardiology 20060801
Title: Rapamycin (sirolimus): a two-edged sword?
Journal: Journal of molecular and cellular cardiology 20060801
Title: Characterisation of the lung toxicity of the cell cycle inhibitor temsirolimus.
Journal: European journal of cancer (Oxford, England : 1990) 20060801
Title: Vascularization and engraftment of a human skin substitute using circulating progenitor cell-derived endothelial cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060801
Title: Chronic inhibition of mammalian target of rapamycin signaling downregulates insulin receptor substrates 1 and 2 and AKT activation: A crossroad between cancer and diabetes?
Journal: Journal of the American Society of Nephrology : JASN 20060801
Title: Long-term effects of novel biolimus eluting DEVAX AXXESS plus nitinol self-expanding stent in a porcine coronary model.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060801
Title: Oral sirolimus after bare metal stent implantation.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060801
Title: Evaluation of the haemodynamic characteristics of drug-eluting stents at implantation and at follow-up.
Journal: European heart journal 20060801
Title: Post-transplant de novo malignancies in renal transplant recipients: the past and present.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20060801
Title: Complementary effects of sirolimus-eluting stents and glycoprotein IIb/IIIa inhibitors for percutaneous coronary intervention in diabetic patients: one-year follow up of a single-centre registry.
Journal: Heart (British Cardiac Society) 20060801
Title: Conversion from calcineurin inhibitor to sirolimus in pediatric chronic allograft nephropathy.
Journal: Pediatric transplantation 20060801
Title: SRL-based immunosuppression vs. CNI minimization in pediatric renal transplant recipients with chronic CNI nephrotoxicity.
Journal: Pediatric transplantation 20060801
Title: Comparison of bare metal stents versus drug-eluting stents on clinical decision making in patients with previous percutaneous coronary intervention admitted for suspected acute coronary syndrome.
Journal: The American journal of cardiology 20060801
Title: Frequency of and risk factors for stent thrombosis after drug-eluting stent implantation during long-term follow-up.
Journal: The American journal of cardiology 20060801
Title: Impact of sirolimus-eluting and Paclitaxel-eluting stents on outcome in patients with diabetes mellitus and stenting in more than one coronary artery.
Journal: The American journal of cardiology 20060801
Title: Neointima inhibition: comparison of effectiveness of non-stent-based local drug delivery and a drug-eluting stent in porcine coronary arteries.
Journal: Radiology 20060801
Title: Documented subacute stent thrombosis within thirty days after stenting with sirolimus-eluting stent (Cypher) for acute myocardial infarction: a Japanese single center retrospective non-randomized study.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20060801
Title: Immunosuppression using the mTOR inhibition mechanism affects replacement of rat liver with transplanted cells.
Journal: Hepatology (Baltimore, Md.) 20060801
Title: Everolimus alters imatinib blood partition in favour of the erythrocyte.
Journal: The Journal of pharmacy and pharmacology 20060801
Title: Sustained intraocular rapamycin delivery effectively prevents high-risk corneal allograft rejection and neovascularization in rabbits.
Journal: Investigative ophthalmology & visual science 20060801
Title: Frequency and determinants of black holes in sirolimus-eluting stent restenosis.
Journal: The Journal of invasive cardiology 20060801
Title: Inhibition of mTOR reduces chronic pressure-overload cardiac hypertrophy and fibrosis.
Journal: Journal of hypertension 20060801
Title: Identification of direct and indirect targets of the Gln3 and Gat1 activators by transcriptional profiling in response to nitrogen availability in the short and long term.
Journal: FEMS yeast research 20060801
Title: Sirolimus-eluting stent in chronic total occlusion: the SICTO study.
Journal: Journal of interventional cardiology 20060801
Title: Clinical and angiographic follow-up after coronary drug-eluting and bare metal stent implantation. Do drug-eluting stents hold the promise?
Journal: Journal of internal medicine 20060801
Title: Late-onset invasive aspergillosis in organ transplant recipients in the current era.
Journal: Medical mycology 20060801
Title: Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo.
Journal: Cancer research 20060801
Title: Sensitive, high throughput HPLC-MS/MS method with on-line sample clean-up for everolimus measurement.
Journal: Therapeutic drug monitoring 20060801
Title: Proteomic analysis of anti-angiogenic effects by a combined treatment with vinblastine and rapamycin in an endothelial cell line.
Journal: Proteomics 20060801
Title: Reverse diastolic intrarenal flow due to calcineurin inhibitor (CNI) toxicity.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060801
Title: Prolactin activates mammalian target-of-rapamycin through phosphatidylinositol 3-kinase and stimulates phosphorylation of p70S6K and 4E-binding protein-1 in lymphoma cells.
Journal: The Journal of endocrinology 20060801
Title: An in vivo platform for translational drug development in pancreatic cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060801
Title: Intracellular signaling in tumor and endothelial cells: The expected and, yet again, the unexpected.
Journal: Cancer cell 20060801
Title: The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor.
Journal: Cancer cell 20060801
Title: Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin.
Journal: Cancer cell 20060801
Title: New hope for RCC patients.
Journal: European journal of cancer (Oxford, England : 1990) 20060801
Title: Alleviation of renal and pulmonary injury by immunomodulation in leptospirosis: hamster model.
Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20060801
Title: Thyroid hormone stimulates protein synthesis in the cardiomyocyte by activating the Akt-mTOR and p70S6K pathways.
Journal: The Journal of biological chemistry 20060728
Title: Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting.
Journal: World journal of gastroenterology 20060728
Title: Cost analysis from two randomized trials of sirolimus-eluting stents versus paclitaxel-eluting stents in high-risk patients with coronary artery disease.
Journal: Journal of the American College of Cardiology 20060718
Title: Effectiveness and safety of sirolimus stent implantation for coronary in-stent restenosis: the TRUE (Tuscany Registry of Sirolimus for Unselected In-Stent Restenosis) Registry.
Journal: Journal of the American College of Cardiology 20060718
Title: Rapamycin-mediated enrichment of T cells with regulatory activity in stimulated CD4+ T cell cultures is not due to the selective expansion of naturally occurring regulatory T cells but to the induction of regulatory functions in conventional CD4+ T cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20060715
Title: Sirolimus-eluting stents versus Paclitaxel-eluting stents in the treatment of coronary artery disease in patients with diabetes mellitus.
Journal: The American journal of cardiology 20060715
Title: Rapamycin delays but does not prevent recovery from acute renal failure: role of acquired tubular resistance.
Journal: Transplantation 20060715
Title: Stimulation of the intestinal phosphate transporter SLC34A2 by the protein kinase mTOR.
Journal: Biochemical and biophysical research communications 20060714
Title: Trials probe new agents for kidney cancer.
Journal: JAMA 20060712
Title: A comparison of angiographic and clinical outcomes after sirolimus-eluting versus paclitaxel-eluting stents for the treatment of in-stent restenosis.
Journal: Chinese medical journal 20060705
Title: Periprocedural and late consequences of overlapping Cypher sirolimus-eluting stents: pooled analysis of five clinical trials.
Journal: Journal of the American College of Cardiology 20060704
Title: Rapid decline of collateral circulation increases susceptibility to myocardial ischemia: the trade-off of successful percutaneous recanalization of chronic total occlusions.
Journal: Journal of the American College of Cardiology 20060704
Title: Pathology of drug-eluting stents in humans: delayed healing and late thrombotic risk.
Journal: Journal of the American College of Cardiology 20060704
Title: Drug-eluting stent thrombosis: increasingly recognized but too frequently overemphasized.
Journal: Journal of the American College of Cardiology 20060704
Title: Role of endothelin-1 and nitric oxide bioavailability in transplant-related vascular injury: comparative effects of rapamycin and cyclosporine.
Journal: Circulation 20060704
Title: Post-transplantation anaemia in adult and paediatric renal allograft recipients-Guy's Hospital experience.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701
Title: Bioluminescence imaging after HSV amplicon vector delivery into brain.
Journal: The journal of gene medicine 20060701
Title: Podospora anserina target of rapamycin.
Journal: Current genetics 20060701
Title: Comparative effects of paclitaxel and rapamycin on smooth muscle migration and survival: role of AKT-dependent signaling.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20060701
Title: Query Chem: a Google-powered web search combining text and chemical structures.
Journal: Bioinformatics (Oxford, England) 20060701
Title: A patient recently transplanted with a living donor kidney develops severe neurological symptoms.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701
Title: Mammalian target of rapamycin inhibitors in sarcomas.
Journal: Current opinion in oncology 20060701
Title: Evaluation of a fluorescent polarization immunoassay for whole blood everolimus determination using samples from renal transplant recipients.
Journal: Clinical biochemistry 20060701
Title: Conversion from calcineurin inhibitor to sirolimus for renal function deterioration in kidney allograft recipients.
Journal: Archives of medical research 20060701
Title: alpha-lipoic acid regulates AMP-activated protein kinase and inhibits insulin secretion from beta cells.
Journal: Diabetologia 20060701
Title: Impact of three or more sirolimus-eluting stents versus paclitaxel-eluting stents on clinical outcomes in patients undergoing percutaneous coronary intervention.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060701
Title: Experimental efficacy of an everolimus eluting cobalt chromium stent.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060701
Title: Very late thrombosis after drug-eluting stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060701
Title: Effects of tacrolimus, cyclosporin A and sirolimus on MG63 cells.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20060701
Title: Sudden hearing loss associated with tacrolimus in a liver transplant recipient.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20060701
Title: Acne in recipients of renal transplantation treated with sirolimus: clinical, microbiologic, histologic, therapeutic, and pathogenic aspects.
Journal: Journal of the American Academy of Dermatology 20060701
Title: Sirolimus-eluting stents at two years: a pooled analysis of SIRIUS, E-SIRIUS, and C-SIRIUS with emphasis on late revascularizations and stent thromboses.
Journal: The American journal of cardiology 20060701
Title: Effects of cyclosporin A, FK506 and rapamycin on calcineurin phosphatase activity in mouse brain.
Journal: IUBMB life 20060701
Title: Everolimus: an immunosuppressive agent in transplantation.
Journal: Expert opinion on pharmacotherapy 20060701
Title: Risk factors for impaired health status differ in women and men treated with percutaneous coronary intervention in the drug-eluting stent era.
Journal: Journal of psychosomatic research 20060701
Title: CYP3A5*3 influences sirolimus oral clearance in de novo and stable renal transplant recipients.
Journal: Clinical pharmacology and therapeutics 20060701
Title: Potential role of proliferation signal inhibitors on atherosclerosis in renal transplant patients.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701
Title: Everolimus in clinical practice--renal transplantation.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701
Title: Conversion to everolimus in maintenance patients--current clinical strategies.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701
Title: Conversion to a proliferation signal inhibitor in a patient with coronary artery disease--a case report.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701
Title: Conversion to everolimus in a patient with arterial hypertension and recurrent cutaneous neoplasia--a case report.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701
Title: Long-term cardiovascular risk in transplantation--insights from the use of everolimus in heart transplantation.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701
Title: Sirolimus-induced pneumonitis presenting as acute respiratory distress syndrome.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060701
Title: Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.
Journal: Cancer research 20060701
Title: Tacrolimus and sirolimus: when bad things happen to good drugs.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060701
Title: Long-term renal allograft function on a tacrolimus-based, pred-free maintenance immunosuppression comparing sirolimus vs. MMF.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060701
Title: Regulation of mTOR by mechanically induced signaling events in skeletal muscle.
Journal: Cell cycle (Georgetown, Tex.) 20060701
Title: Inhibition of the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in hematologic malignancies.
Journal: Current treatment options in oncology 20060701
Title: Coronary artery restenosis: vascular biology and emerging therapeutic strategies.
Journal: Expert review of cardiovascular therapy 20060701
Title: [Inhibition of growth and metastasis of hepatocellular carcinoma by rapamycin: experiment with mice].
Journal: Zhonghua yi xue za zhi 20060627
Title: [Local applied slow-releasing rapamycin inhibits neointima hyperplasia in vein graft].
Journal: Zhonghua yi xue za zhi 20060627
Title: The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity.
Journal: The EMBO journal 20060621
Title: PTEN takes center stage in cancer stem cell research, works as tumor suppressor.
Journal: Journal of the National Cancer Institute 20060621
Title: Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: results from the PREMIER registry.
Journal: Circulation 20060620
Title: Drug-eluting stent restenosis the pattern predicts the outcome.
Journal: Journal of the American College of Cardiology 20060620
Title: Narrative review: drug-eluting stents for the management of restenosis: a critical appraisal of the evidence.
Journal: Annals of internal medicine 20060620
Title: A role for the mTOR pathway in surface expression of AMPA receptors.
Journal: Neuroscience letters 20060619
Title: Activation of the mTOR signalling pathway is required for pancreatic growth in protease-inhibitor-fed mice.
Journal: The Journal of physiology 20060615
Title: Images in cardiovascular medicine. Severe endothelial dysfunction after sirolimus-eluting stent implantation.
Journal: Circulation 20060613
Title: [Diffuse lung diseases].
Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20060610
Title: General repression of RNA polymerase III transcription is triggered by protein phosphatase type 2A-mediated dephosphorylation of Maf1.
Journal: Molecular cell 20060609
Title: Evaluation of rapamycin chemical stability in volatile-organic solvents by HPLC.
Journal: Journal of pharmaceutical and biomedical analysis 20060607
Title: A randomized comparison of sirolimus-eluting stent with balloon angioplasty in patients with in-stent restenosis: results of the Restenosis Intrastent: Balloon Angioplasty Versus Elective Sirolimus-Eluting Stenting (RIBS-II) trial.
Journal: Journal of the American College of Cardiology 20060606
Title: Vascular effects of sirolimus-eluting versus bare-metal stents in diabetic patients: three-dimensional ultrasound results of the Diabetes and Sirolimus-Eluting Stent (DIABETES) Trial.
Journal: Journal of the American College of Cardiology 20060606
Title: Zotarolimus (ABT-578) eluting stents.
Journal: Advanced drug delivery reviews 20060603
Title: Clinical experience and applications of drug-eluting stents in the noncoronary vasculature, bile duct and esophagus.
Journal: Advanced drug delivery reviews 20060603
Title: Countervailing effects of rapamycin (sirolimus) on nuclear factor-kappa B activities in neointimal and medial smooth muscle cells.
Journal: Atherosclerosis 20060601
Title: Sirolimus-eluting stent fracture with thrombus, visualization by optical coherence tomography.
Journal: European heart journal 20060601
Title: Insulin-facilitated increase of muscle protein synthesis after resistance exercise involves a MAP kinase pathway.
Journal: American journal of physiology. Endocrinology and metabolism 20060601
Title: Rapamycin antagonizes NF-kappaB nuclear translocation activated by TNF-alpha in primary vascular smooth muscle cells and enhances apoptosis.
Journal: American journal of physiology. Heart and circulatory physiology 20060601
Title: Increase in S6K1 phosphorylation in human skeletal muscle following resistance exercise occurs mainly in type II muscle fibers.
Journal: American journal of physiology. Endocrinology and metabolism 20060601
Title: Insulin and oxidative stress modulate proliferation of rat ovarian theca-interstitial cells through diverse signal transduction pathways.
Journal: Biology of reproduction 20060601
Title: Effect of severe short-term malnutrition on diaphragm muscle signal transduction pathways influencing protein turnover.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20060601
Title: Bifurcation stenting with drug eluting stents: illustration of the crush technique.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060601
Title: Intravascular ultrasound predictors of angiographic restenosis after sirolimus-eluting stent implantation.
Journal: European heart journal 20060601
Title: 'Head-to-head comparison between sirolimus-eluting and paclitaxel-eluting stents in patients with complex coronary artery disease: an intravascular ultrasound study'.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060601
Title: Rapamycin induces a caspase-independent cell death in human monocytes.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060601
Title: Tacrolimus with mycophenolate mofetil (MMF) or sirolimus vs. cyclosporine with MMF in cardiac transplant patients: 1-year report.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060601
Title: Everolimus and reduced cyclosporine trough levels in maintenance heart transplant recipients.
Journal: Transplant immunology 20060601
Title: Recent developments in targeting the mammalian target of rapamycin (mTOR) kinase pathway.
Journal: Anti-cancer drugs 20060601
Title: Conversion from calcineurin inhibitor to sirolimus in pediatric chronic allograft nephropathy.
Journal: Pediatric transplantation 20060601
Title: Rapamycin, an mTOR inhibitor, disrupts triglyceride metabolism in guinea pigs.
Journal: Metabolism: clinical and experimental 20060601
Title: Very late thrombosis after sirolimus-eluting stent implantation.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20060601
Title: A meta-analysis of trials comparing Cypher and Taxus stents in patients with obstructive coronary artery disease.
Journal: British journal of clinical pharmacology 20060601
Title: Rapamycin and chronic kidney disease: beyond the inhibition of inflammation.
Journal: Kidney international 20060601
Title: The fate of patients with clinical recurrence after sirolimus-eluting stent implantation (a two-year follow-up analysis from the SIRIUS trial).
Journal: The American journal of cardiology 20060601
Title: Overcoming T cell-mediated rejection of bone marrow allografts by T-regulatory cells: synergism with veto cells and rapamycin.
Journal: Experimental hematology 20060601
Title: The incidence of acute cellular rejection after lung transplantation: a comparative study of anti-thymocyte globulin and daclizumab.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060601
Title: Sirolimus for Kaposi's sarcoma.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060601
Title: Induction of tolerance in type 1 diabetes via both CD4+CD25+ T regulatory cells and T regulatory type 1 cells.
Journal: Diabetes 20060601
Title: Rapamycin attenuates unilateral ureteral obstruction-induced renal fibrosis.
Journal: Kidney international 20060601
Title: Antiangiogenic potential of the Mammalian target of rapamycin inhibitor temsirolimus.
Journal: Cancer research 20060601
Title: Perspectives in central nervous system malignancies.
Journal: IDrugs : the investigational drugs journal 20060601
Title: Antilymphoid antibody preconditioning and tacrolimus monotherapy for pediatric kidney transplantation.
Journal: The Journal of pediatrics 20060601
Title: Solitary pancreas transplantation for life-threatening allergy to human insulin.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20060601
Title: Percutaneous stenting of the left main with drug eluting stents for in-stent restenosis: immediate- and long-term results.
Journal: The Journal of invasive cardiology 20060601
Title: Sirolimus-induced pulmonary hypersensitivity associated with a CD4 T-cell infiltrate.
Journal: Chest 20060601
Title: Drug-eluting stents for infrainguinal occlusive disease: progress and challenges.
Journal: Seminars in vascular surgery 20060601
Title: Targeting mTOR for cancer treatment.
Journal: Current opinion in investigational drugs (London, England : 2000) 20060601
Title: Conversion from calcineurin inhibitors to sirolimus in patients with chronic renal allograft dysfunction.
Journal: Transplantation proceedings 20060601
Title: Sirolimus-induced intractable chronic diarrhea: a case report.
Journal: Transplantation proceedings 20060601
Title: New therapies in the treatment of breast cancer.
Journal: Seminars in oncology 20060601
Title: Molecular targeting therapy for renal cell carcinoma.
Journal: International journal of clinical oncology 20060601
Title: A comparison of measured trough levels and abbreviated AUC estimation by limited sampling strategies for monitoring mycophenolic acid exposure in stable heart transplant patients receiving cyclosporin A-containing and cyclosporin A-free immunosuppressive regimens.
Journal: Clinical therapeutics 20060601
Title: Switching immunosuppressive drugs in kidney transplant recipients: 'show me the evidence'.
Journal: Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20060601
Title: No effect of sirolimus for kaposi sarcoma in a renal transplant recipient.
Journal: Transplantation 20060527
Title: Autophagy: is it cancer's friend or foe?
Journal: Science (New York, N.Y.) 20060526
Title: Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells.
Journal: Nature 20060525
Title: Functional genomics identifies TOR-regulated genes that control growth and division.
Journal: Current biology : CB 20060523
Title: Conversion to sirolimus immunosuppression in liver transplantation recipients with hepatocellular carcinoma: Report of an initial experience.
Journal: World journal of gastroenterology 20060521
Title: Predictive factors of restenosis after coronary implantation of sirolimus- or paclitaxel-eluting stents.
Journal: Circulation 20060516
Title: Long-term outcomes after stenting of bifurcation lesions with the 'crush' technique: predictors of an adverse outcome.
Journal: Journal of the American College of Cardiology 20060516
Title: Incomplete neointimal coverage of sirolimus-eluting stents: angioscopic findings.
Journal: Journal of the American College of Cardiology 20060516
Title: Target of rapamycin inhibitors (sirolimus and everolimus) for primary immunosuppression of kidney transplant recipients: a systematic review and meta-analysis of randomized trials.
Journal: Transplantation 20060515
Title: Stm1p, a ribosome-associated protein, is important for protein synthesis in Saccharomyces cerevisiae under nutritional stress conditions.
Journal: Journal of molecular biology 20060512
Title: Neuroscience. Regulating energy balance: the substrate strikes back.
Journal: Science (New York, N.Y.) 20060512
Title: Hypothalamic mTOR signaling regulates food intake.
Journal: Science (New York, N.Y.) 20060512
Title: Predictive factors of cardiac events after implantation of sirolimus-eluting stents for treatment of in-stent restenosis.
Journal: International journal of cardiology 20060510
Title: Involvement of protein synthesis and degradation in long-term potentiation of Schaffer collateral CA1 synapses.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060503
Title: Life-threatening coronary artery spasm following sirolimus-eluting stent deployment.
Journal: Journal of the American College of Cardiology 20060502
Title: Endothelial dysfunction after drug-eluting stent was never predicted in preclinical studies.
Journal: Journal of the American College of Cardiology 20060502
Title: Limitations of crush technique.
Journal: Journal of the American College of Cardiology 20060502
Title: Drug eluting stents: an updated meta-analysis of randomised controlled trials.
Journal: Heart (British Cardiac Society) 20060501
Title: Late coronary thrombosis in a sirolimus-eluting stent due to the lack of neointimal coverage.
Journal: European heart journal 20060501
Title: Efficacy of drug eluting stents in patients with and without diabetes mellitus: indirect comparison of controlled trials.
Journal: Heart (British Cardiac Society) 20060501
Title: In vivo antitumor effect of the mTOR inhibitor CCI-779 and gemcitabine in xenograft models of human pancreatic cancer.
Journal: International journal of cancer 20060501
Title: Abnormal growth of smooth muscle-like cells in lymphangioleiomyomatosis: Role for tumor suppressor TSC2.
Journal: American journal of respiratory cell and molecular biology 20060501
Title: Interferon-gamma-induced dephosphorylation of STAT3 and apoptosis are dependent on the mTOR pathway.
Journal: Experimental cell research 20060501
Title: Role of drug eluting stents in diabetic patients.
Journal: Heart (British Cardiac Society) 20060501
Title: Drug-eluting stents studies in mice: do we need atherosclerosis to study restenosis?
Journal: Vascular pharmacology 20060501
Title: Inhibition of the mammalian target of rapamycin (mTOR) by rapamycin increases chemosensitivity of CaSki cells to paclitaxel.
Journal: European journal of cancer (Oxford, England : 1990) 20060501
Title: Locally administered antiproliferative drugs inhibit hypercontractility to serotonin in balloon-injured pig coronary artery.
Journal: Vascular pharmacology 20060501
Title: Differentiation of innovator versus generic cyclosporine via a drug interaction on sirolimus.
Journal: European journal of clinical pharmacology 20060501
Title: Mammalian target of rapamycin pathway blockade slows progression of diabetic kidney disease in rats.
Journal: Journal of the American Society of Nephrology : JASN 20060501
Title: Wound healing complications with de novo sirolimus versus mycophenolate mofetil-based regimen in cardiac transplant recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060501
Title: Sequential kidney/islet transplantation: efficacy and safety assessment of a steroid-free immunosuppression protocol.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060501
Title: Colonic perforation associated with leukocytoclastic vasculitis caused by Sirolimus toxicity following renal transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20060501
Title: Sirolimus-induced remission of posttransplantation lymphoproliferative disorder.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20060501
Title: Comparison of safety and efficacy of sirolimus-eluting stents versus bare metal stents in patients with ST-segment elevation myocardial infarction.
Journal: The American journal of cardiology 20060501
Title: C-Reactive protein, clinical outcome, and restenosis rates after implantation of different drug-eluting stents.
Journal: The American journal of cardiology 20060501
Title: A prospective registry to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions using the 'crush technique'.
Journal: The American journal of cardiology 20060501
Title: Voriconazole and sirolimus coadministration after allogeneic hematopoietic stem cell transplantation.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20060501
Title: Sirolimus-eluting coronary stents in small vessels.
Journal: American heart journal 20060501
Title: Survival signaling by Notch1: mammalian target of rapamycin (mTOR)-dependent inhibition of p53.
Journal: Cancer research 20060501
Title: Everolimus (RAD) inhibits in vivo growth of murine squamous cell carcinoma (SCC VII).
Journal: The Laryngoscope 20060501
Title: Comparison between sirolimus- and Paclitaxel-eluting stents for the treatment of chronic total occlusions.
Journal: The Journal of invasive cardiology 20060501
Title: Sirolimus or paclitaxel drug-eluting stents for treatment of chronic total occlusions of coronary arteries: much ado about very little.
Journal: The Journal of invasive cardiology 20060501
Title: Sirolimus rescue for tacrolimus-associated post-transplant autoimmune hemolytic anemia.
Journal: Pediatric transplantation 20060501
Title: Early renal benefit of rapamycin combined with reduced calcineurin inhibitor dose in pediatric heart transplantation patients.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060501
Title: Integrated coronary revascularization with drug-eluting stents: immediate and seven-month outcome.
Journal: The Journal of thoracic and cardiovascular surgery 20060501
Title: Autophagy: A protective mechanism in response to stress and inflammation.
Journal: Current opinion in investigational drugs (London, England : 2000) 20060501
Title: Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer.
Journal: Molecular cancer therapeutics 20060501
Title: Green tea extract and (-)-epigallocatechin-3-gallate inhibit hypoxia- and serum-induced HIF-1alpha protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells.
Journal: Molecular cancer therapeutics 20060501
Title: Possible molecular target therapy with rapamycin in MDS.
Journal: Leukemia & lymphoma 20060501
Title: Cutaneous leukocytoclastic vasculitis in a patient with myelodysplastic syndrome after therapy with the rapamycin analogue everolimus: case report and review of the literature.
Journal: Leukemia & lymphoma 20060501
Title: Drug eluting stents: data from a clinical registry.
Journal: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20060501
Title: Long-term results of kidney transplantation with cyclosporine- and everolimus-based immunosuppression.
Journal: Transplantation proceedings 20060501
Title: Incidence of posttransplant diabetes mellitus in kidney transplant recipients immunosuppressed with sirolimus in combination with cyclosporine.
Journal: Transplantation proceedings 20060501
Title: Lymphocele after renal transplantation: the influence of the immunosuppressive therapy.
Journal: Transplantation proceedings 20060501
Title: [Effects of rapamycin on Rho-kinase and p27 mRNA expressions in a porcine coronary intimal proliferation model induced by interleukin-1beta].
Journal: Zhonghua xin xue guan bing za zhi 20060501
Title: mTOR, Akt, S6 kinases and the control of skeletal muscle growth.
Journal: Bulletin du cancer 20060501
Title: [The PI3K/Akt/mTOR pathway: a new therapeutic target in the treatment of acute myeloid leukemia].
Journal: Bulletin du cancer 20060501
Title: CCI-779 inhibits rhabdomyosarcoma xenograft growth by an antiangiogenic mechanism linked to the targeting of mTOR/Hif-1alpha/VEGF signaling.
Journal: Neoplasia (New York, N.Y.) 20060501
Title: Sirolimus early graft nephrotoxicity: clinical and experimental data.
Journal: Current drug safety 20060501
Title: Inhibition of corneal neovascularization by rapamycin.
Journal: Experimental & molecular medicine 20060430
Title: Pancreas transplantation utilizing thymoglobulin, sirolimus, and cyclosporine.
Journal: Transplantation 20060427
Title: GATA factor translation is the final downstream step in the amino acid/target-of-rapamycin-mediated vitellogenin gene expression in the anautogenous mosquito Aedes aegypti.
Journal: The Journal of biological chemistry 20060421
Title: Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB.
Journal: Molecular cell 20060421
Title: mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin.
Journal: The EMBO journal 20060419
Title: Target of rapamycin inhibitors (TOR-I; sirolimus and everolimus) for primary immunosuppression in kidney transplant recipients.
Journal: The Cochrane database of systematic reviews 20060419
Title: Oral rapamycin after coronary bare-metal stent implantation to prevent restenosis: the Prospective, Randomized Oral Rapamycin in Argentina (ORAR II) Study.
Journal: Journal of the American College of Cardiology 20060418
Title: Distal left main coronary disease is a major predictor of outcome in patients undergoing percutaneous intervention in the drug-eluting stent era: an integrated clinical and angiographic analysis based on the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) and Taxus-Stent Evaluated At Rotterdam Cardiology Hospital (T-SEARCH) registries.
Journal: Journal of the American College of Cardiology 20060418
Title: Mechanical stimuli and nutrients regulate rapamycin-sensitive signaling through distinct mechanisms in skeletal muscle.
Journal: Journal of cellular biochemistry 20060415
Title: SUMO modification through rapamycin-mediated heterodimerization reveals a dual role for Ubc9 in targeting RanGAP1 to nuclear pore complexes.
Journal: Experimental cell research 20060415
Title: Improved renal function after conversion from tacrolimus/sirolimus to tacrolimus/mycophenolate mofetil in kidney transplant recipients.
Journal: Transplantation 20060415
Title: Comparison of sirolimus versus paclitaxel eluting stents for treatment of coronary in-stent restenosis.
Journal: The American journal of cardiology 20060415
Title: Usefulness and safety of percutaneous coronary interventions for cardiac transplant vasculopathy.
Journal: The American journal of cardiology 20060415
Title: Rapamycin inhibits growth of premalignant and malignant mammary lesions in a mouse model of ductal carcinoma in situ.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060415
Title: [Drug-eluting stents: do they keep their promises?].
Journal: Praxis 20060412
Title: Outcomes of using Firebird rapamycin eluting stents in routine coronary intervention practice: one-year results from the pilot study of Firebird in China registry.
Journal: Chinese medical journal 20060405
Title: Two-year outcomes after sirolimus-eluting stent implantation: results from the Sirolimus-Eluting Stent in de Novo Native Coronary Lesions (SIRIUS) trial.
Journal: Journal of the American College of Cardiology 20060404
Title: Sirolimus-eluting stents remain superior to bare-metal stents at two years: medium-term results from the Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry.
Journal: Journal of the American College of Cardiology 20060404
Title: Drug-eluting stents are safe and effective: right or wrong?
Journal: Journal of the American College of Cardiology 20060404
Title: Summaries for patients. Twenty-four cases of pneumonitis in kidney transplantation recipients receiving sirolimus.
Journal: Annals of internal medicine 20060404
Title: Brief communication: sirolimus-associated pneumonitis: 24 cases in renal transplant recipients.
Journal: Annals of internal medicine 20060404
Title: Identification and characterization of a constitutively T-loop phosphorylated and active recombinant S6K1: expression, purification, and enzymatic studies in a high capacity non-radioactive TR-FRET Lance assay.
Journal: Protein expression and purification 20060401
Title: mTOR pathway inhibition attenuates skeletal muscle growth induced by stretching.
Journal: Cell and tissue research 20060401
Title: Immunoglobulin G from patients with Graves' disease induces interleukin-16 and RANTES expression in cultured human thyrocytes: a putative mechanism for T-cell infiltration of the thyroid in autoimmune disease.
Journal: Endocrinology 20060401
Title: Zotarolimus-eluting stents reduce experimental coronary artery neointimal hyperplasia after 4 weeks.
Journal: European heart journal 20060401
Title: Rapamycin pre-treatment protects against apoptosis.
Journal: Human molecular genetics 20060401
Title: Impact of overlapping drug-eluting stents in patients undergoing percutaneous coronary intervention.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060401
Title: Prolonged survival of allogeneic islets in cynomolgus monkeys after short-term anti-CD154-based therapy: nonimmunologic graft failure?
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060401
Title: Rapamycin attenuates liver graft injury in cirrhotic recipient--the significance of down-regulation of Rho-ROCK-VEGF pathway.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060401
Title: Effects of rapamycin on number activity and eNOS of endothelial progenitor cells from peripheral blood.
Journal: Cell proliferation 20060401
Title: Multi-center evaluation of analytical performance of the microparticle enzyme immunoassay for sirolimus.
Journal: Clinical biochemistry 20060401
Title: Comparison of the effectiveness of sirolimus- and paclitaxel-eluting stents for small coronary artery lesions.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060401
Title: Everolimus in pulmonary transplantation: pharmacokinetics and exposure-response relationships.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060401
Title: Acute renal failure in a liver transplant patient after treatment with sirolimus.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20060401
Title: Are drug-eluting stents cost-effective when compared with bare-metal stents in a real-world setting?
Journal: Nature clinical practice. Cardiovascular medicine 20060401
Title: Percutaneous transluminal angioplasty for treatment of ''below-the-knee'' critical limb ischemia: early outcomes following the use of sirolimus-eluting stents.
Journal: The Journal of cardiovascular surgery 20060401
Title: Simultaneous corticosteroid avoidance and calcineurin inhibitor minimization in renal transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20060401
Title: Sirolimus and FK778: a comparison of two anti-proliferative immunosuppressants for prevention of experimental obliterative airway disease.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20060401
Title: How to revascularize patients with diabetes mellitus: bypass or stents and drugs?
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20060401
Title: Managing the introduction of expensive medical procedures: use of a registry.
Journal: Journal of health services research & policy 20060401
Title: [Technical evolution of the stent].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20060401
Title: Comparison of the reintroduced MEIA assay with HPLC-MS/MS for the determination of whole-blood sirolimus from transplant recipients.
Journal: Therapeutic drug monitoring 20060401
Title: Determination of mycophenolic acid plasma levels in renal transplant recipients co-administered sirolimus: comparison of an enzyme multiplied immunoassay technique (EMIT) and liquid chromatography-tandem mass spectrometry.
Journal: Therapeutic drug monitoring 20060401
Title: Resolution of sirolimus-induced pneumonitis after conversion to everolimus.
Journal: Transplantation proceedings 20060401
Title: Side effects of sirolimus.
Journal: Transplantation proceedings 20060401
Title: Antiproliferative and overadditive effects of everolimus and mycophenolate mofetil in pancreas and lung cancer cells in vitro.
Journal: Transplantation proceedings 20060401
Title: Recommendations for use of everolimus after heart transplantation: results from a Latin-American Consensus Meeting.
Journal: Transplantation proceedings 20060401
Title: Efficacy of sirolimus-eluting stents as compared to paclitaxel-eluting stents for saphenous vein graft intervention.
Journal: Journal of interventional cardiology 20060401
Title: Two-year follow-up of sirolimus-eluting stents for the treatment of proximal left anterior descending coronary artery stenosis.
Journal: Journal of interventional cardiology 20060401
Title: Novel regulatory properties of Saccharomyces cerevisiae Arp4.
Journal: Journal of biochemistry 20060401
Title: [Sirolimus-eluting stents for the treatment of stenoses in small coronary arteries: what have we learned?].
Journal: Arquivos brasileiros de cardiologia 20060401
Title: [Comparative analysis of intimal hyperplasia after sirolimus-eluting stent and thin-strut bare-metal stent implantation in small coronary arteries].
Journal: Arquivos brasileiros de cardiologia 20060401
Title: [Molecular targets in colon cancer].
Journal: Therapeutische Umschau. Revue therapeutique 20060401
Title: Long-term follow up after coronary sirolimus drug-eluting stent implantation for cardiac transplant arteriopathy.
Journal: The Journal of invasive cardiology 20060401
Title: Long-term follow up of diabetic patients treated with sirolimus-eluting stents. An angiographic and three-dimensional intravascular ultrasound study.
Journal: The Journal of invasive cardiology 20060401
Title: Future directions in the treatment of hormone-sensitive advanced breast cancer: the RAD001 (Everolimus)-letrozole clinical program.
Journal: Seminars in oncology 20060401
Title: [The femoral artery: the most complex peripheral vessel].
Journal: Herz 20060401
Title: [The impact of expansion of sirolimus eluting stent on intimal hyperplasia: an intravascular ultrasound study].
Journal: Zhonghua xin xue guan bing za zhi 20060401
Title: Future anti-catabolic therapeutic targets in bone disease.
Journal: Annals of the New York Academy of Sciences 20060401
Title: A randomized long-term trial of tacrolimus/sirolimus versus tacrolimums/mycophenolate versus cyclosporine/sirolimus in renal transplantation: three-year analysis.
Journal: Transplantation 20060327
Title: Stimulation of the creatine transporter SLC6A8 by the protein kinase mTOR.
Journal: Biochemical and biophysical research communications 20060324
Title: Successful management of left main coronary artery stenosis with a paclitaxel-eluting stent in Takayasu's arteritis.
Journal: International journal of cardiology 20060322
Title: Biosynthesis of pipecolic acid by RapL, a lysine cyclodeaminase encoded in the rapamycin gene cluster.
Journal: Journal of the American Chemical Society 20060322
Title: Safety of coronary sirolimus-eluting stents in daily clinical practice: one-year follow-up of the e-Cypher registry.
Journal: Circulation 20060321
Title: The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20060321
Title: Blockade of CD154-CD40 pathway induces interleukin-10 dependent T regulatory type 1 like cells.
Journal: Chinese medical journal 20060320
Title: A nuclear transport signal in mammalian target of rapamycin is critical for its cytoplasmic signaling to S6 kinase 1.
Journal: The Journal of biological chemistry 20060317
Title: Mammalian target of rapamycin (mTOR) regulates both proliferation of megakaryocyte progenitors and late stages of megakaryocyte differentiation.
Journal: Blood 20060315
Title: Impact of chronic renal insufficiency on clinical outcomes in patients undergoing percutaneous coronary intervention with sirolimus-eluting stents versus bare metal stents.
Journal: The American journal of cardiology 20060315
Title: Sirolimus-eluting stents vs vascular brachytherapy for in-stent restenosis within bare-metal stents: the SISR randomized trial.
Journal: JAMA 20060315
Title: Brachytherapy for in-stent restenosis: a distant second choice to drug-eluting stent placement.
Journal: JAMA 20060315
Title: Switch from calcineurin inhibitors to sirolimus-induced renal recovery in heart transplant recipients in the midterm follow-up.
Journal: Transplantation 20060315
Title: An open prospective pilot study on the use of rapamycin after penetrating high-risk keratoplasty.
Journal: Transplantation 20060315
Title: New drug application 21-628, Certican (everolimus), for the proposed indication of prophylaxis of rejection in heart transplantation: report from the Cardiovascular and Renal Drugs Advisory Committee, US Food and Drug Administration, November 16, 2005, Rockville, Md.
Journal: Circulation 20060314
Title: Clinical islet transplantation in type 1 diabetes mellitus: results of Australia's first trial.
Journal: The Medical journal of Australia 20060306
Title: Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD).
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060301
Title: Rapamycin inhibits hTERT telomerase mRNA expression, independent of cell cycle arrest.
Journal: Gynecologic oncology 20060301
Title: Molecular activity of sirolimus and its possible application in tuberous sclerosis treatment.
Journal: Medicinal research reviews 20060301
Title: Conversion from calcineurin inhibitors to sirolimus in chronic allograft nephropathy: benefits and risks.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060301
Title: [Sirolimus-associated interstitial pneumonitis in a renal transplant patient].
Journal: La Revue de medecine interne 20060301
Title: Sirolimus in de novo heart transplant recipients with severe renal impairment.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20060301
Title: Rapamycin causes regression of astrocytomas in tuberous sclerosis complex.
Journal: Annals of neurology 20060301
Title: Complete avoidance of calcineurin inhibitors in renal transplantation: a randomized trial comparing sirolimus and tacrolimus.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060301
Title: Tacrolimus combined with two different dosages of sirolimus in kidney transplantation: results of a multicenter study.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060301
Title: Restenosis of a sirolimus drug-eluting stent: aorto-ostial involvement of the proximal right coronary artery.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060301
Title: Novel apoptosis assay to analyze immunosuppression.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060301
Title: Differing responses of Gat1 and Gln3 phosphorylation and localization to rapamycin and methionine sulfoximine treatment in Saccharomyces cerevisiae.
Journal: FEMS yeast research 20060301
Title: Drug-eluting stent-supported percutaneous coronary intervention for chronic total coronary occlusion.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060301
Title: Is late luminal loss an accurate predictor of the clinical effectiveness of drug-eluting stents in the coronary arteries?
Journal: The American journal of cardiology 20060301
Title: Impact of three or more versus a single sirolimus-eluting stent on outcomes in patients who undergo percutaneous coronary intervention.
Journal: The American journal of cardiology 20060301
Title: Percutaneous coronary interventions with stents in cardiac transplant recipients.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060301
Title: Mechanistic insights into achievement of cardiac allograft long-term survival by treatment with immature dendritic cells and sub-dose sirolimus.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060301
Title: Calcium signaling stimulates translation of HIF-alpha during hypoxia.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301
Title: Perspectives in gynecologic oncology -- Third European Conference.
Journal: IDrugs : the investigational drugs journal 20060301
Title: Using 'bumps' and 'holes' to control protein activity.
Journal: Nature methods 20060301
Title: IRS-1: auditing the effectiveness of mTOR inhibitors.
Journal: Cancer cell 20060301
Title: Individualization of immunosuppressive therapy. III. Sirolimus associated with a reduced incidence of malignancy.
Journal: Transplantation proceedings 20060301
Title: Cutaneous effects of sirolimus in renal transplant recipients.
Journal: Journal of drugs in dermatology : JDD 20060301
Title: [Stroma-targeted palliative tumor therapy with biomodulators].
Journal: Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20060301
Title: Economic evaluation of drug-eluting stents in Japan.
Journal: The Keio journal of medicine 20060301
Title: [Two-year clinical follow-up in 200 patients receiving sirolimus-eluting stents in lesions at a high risk of restenosis].
Journal: Revista espanola de cardiologia 20060301
Title: Correlates and long-term outcomes of angiographically proven stent thrombosis with sirolimus- and paclitaxel-eluting stents.
Journal: Circulation 20060227
Title: Human allograft arterial injury is ameliorated by sirolimus and cyclosporine and correlates with suppression of interferon-gamma.
Journal: Transplantation 20060227
Title: Tacrolimus-associated optic neuropathy after pancreatic islet transplantation using a sirolimus/tacrolimus immunosuppressive regimen.
Journal: Transplantation 20060227
Title: Pregnancy under sirolimus-based immunosuppression.
Journal: Transplantation 20060227
Title: Sirolimus- vs paclitaxel-eluting stents in de novo coronary artery lesions: the REALITY trial: a randomized controlled trial.
Journal: JAMA 20060222
Title: Wish list and REALITY: choice of stents and end points for treatment of de novo coronary artery lesions.
Journal: JAMA 20060222
Title: Sirolimus and Paclitaxel on polymer-based drug-eluting stents: similar but different.
Journal: Journal of the American College of Cardiology 20060221
Title: Serial angiographic follow-up of sirolimus-eluting stents for unprotected left main coronary artery revascularization.
Journal: Journal of the American College of Cardiology 20060221
Title: Drug-eluting stenting for unprotected left main coronary artery disease: are we ready to replace bypass surgery?
Journal: Journal of the American College of Cardiology 20060221
Title: Late stent malapposition and marked positive vessel remodeling after sirolimus-eluting coronary stent implantation.
Journal: Chinese medical journal 20060220
Title: Effects of drug combinations on smooth muscle cell proliferation: an isobolographic analysis.
Journal: European journal of pharmacology 20060217
Title: In yeast, loss of Hog1 leads to osmosensitivity of autophagy.
Journal: The Biochemical journal 20060215
Title: A comparison of sirolimus vs. calcineurin inhibitor-based immunosuppressive therapies in liver transplantation.
Journal: Alimentary pharmacology & therapeutics 20060215
Title: Inhibition of TPO-induced MEK or mTOR activity induces opposite effects on the ploidy of human differentiating megakaryocytes.
Journal: Journal of cell science 20060215
Title: Comparison between sirolimus- and paclitaxel-eluting stent in T-cell subsets redistribution.
Journal: The American journal of cardiology 20060215
Title: Angiographic pattern of restenosis following implantation of overlapping sirolimus-eluting (Cypher) stents.
Journal: The American journal of cardiology 20060215
Title: Predictors of restenosis after placement of drug-eluting stents in one or more coronary arteries.
Journal: The American journal of cardiology 20060215
Title: Posttransplant diabetes mellitus in kidney transplant recipients receiving calcineurin or mTOR inhibitor drugs.
Journal: Transplantation 20060215
Title: Conversion to sirolimus and mycophenolate can attenuate the progression of bronchiolitis obliterans syndrome and improves renal function after lung transplantation.
Journal: Transplantation 20060215
Title: Rapamycin does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells.
Journal: Transplantation 20060215
Title: Mechanism by which mammalian target of rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced apoptosis.
Journal: Cancer research 20060215
Title: Glucose-stimulated DNA synthesis through mammalian target of rapamycin (mTOR) is regulated by KATP channels: effects on cell cycle progression in rodent islets.
Journal: The Journal of biological chemistry 20060210
Title: Sirolimus-eluting versus paclitaxel-eluting stent implantation for the percutaneous treatment of left main coronary artery disease: a combined RESEARCH and T-SEARCH long-term analysis.
Journal: Journal of the American College of Cardiology 20060207
Title: Regression of cutaneous and gastrointestinal telangiectasia with sirolimus and aspirin in a patient with hereditary hemorrhagic telangiectasia.
Journal: Annals of internal medicine 20060207
Title: Inhibition of mTOR signaling with rapamycin attenuates renal hypertrophy in the early diabetic mice.
Journal: Biochemical and biophysical research communications 20060203
Title: Coronary-artery stents.
Journal: The New England journal of medicine 20060202
Title: Simultaneous determination of everolimus and cyclosporine concentrations by HPLC with ultraviolet detection.
Journal: Clinica chimica acta; international journal of clinical chemistry 20060201
Title: The mTOR inhibitor CCI-779 induces apoptosis and inhibits growth in preclinical models of primary adult human ALL.
Journal: Blood 20060201
Title: Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells.
Journal: Blood 20060201
Title: Adaptor heat shock protein complex formation regulates trafficking of the asialoglycoprotein receptor.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20060201
Title: Conversion from calcineurin inhibitors to sirolimus in chronic allograft dysfunction: changes in glomerular haemodynamics and proteinuria.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060201
Title: The Saccharomyces cerevisiae phosphatase activator RRD1 is required to modulate gene expression in response to rapamycin exposure.
Journal: Genetics 20060201
Title: Involvement of multiple phosphatidylinositol 3-kinase-dependent pathways in the persistence of late-phase long term potentiation expression.
Journal: Neuroscience 20060201
Title: mTOR and cancer: reason for dancing at the crossroads?
Journal: Current opinion in genetics & development 20060201
Title: Rapamycin alleviates toxicity of different aggregate-prone proteins.
Journal: Human molecular genetics 20060201
Title: Individualizing combination of two antiproliferative immunosuppressants with pharmacodynamic modeling of stimulated lymphocyte responses.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060201
Title: Prevention of carotid artery restenosis after sirolimus-coated stent implantation in pigs.
Journal: Stroke 20060201
Title: Comparison of sirolimus-eluting stent, paclitaxel-eluting stent, and bare metal stent in the treatment of long coronary lesions.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060201
Title: Revisiting late loss and neointimal volumetric measurements in a drug-eluting stent trial: analysis from the SPIRIT FIRST trial.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060201
Title: Mycotic aneurysms after sirolimus-eluting coronary stenting.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060201
Title: Randomized trial of paclitaxel- and sirolimus-eluting stents in small coronary vessels.
Journal: European heart journal 20060201
Title: Microarray-based method for monitoring yeast overexpression strains reveals small-molecule targets in TOR pathway.
Journal: Nature chemical biology 20060201
Title: Pharmacokinetics and metabolic disposition of sirolimus in healthy male volunteers after a single oral dose.
Journal: Therapeutic drug monitoring 20060201
Title: Sirolimus-associated heavy proteinuria in a renal transplant recipient: evidence for a tubular mechanism.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060201
Title: Update on drug-eluting stents for prevention of restenosis.
Journal: Asian cardiovascular & thoracic annals 20060201
Title: Sirolimus- or paclitaxel-eluting stents for coronary artery revascularisation.
Journal: Expert opinion on pharmacotherapy 20060201
Title: Sirolimus therapy after early cyclosporine withdrawal reduces the risk for cancer in adult renal transplantation.
Journal: Journal of the American Society of Nephrology : JASN 20060201
Title: Role of Erk1/2, p70s6K, and eNOS in isoflurane-induced cardioprotection during early reperfusion in vivo.
Journal: Canadian journal of anaesthesia = Journal canadien d'anesthesie 20060201
Title: Renal calcium handling after rapamycin conversion in chronic allograft dysfunction.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20060201
Title: Reversible sirolimus-associated pneumonitis after heart transplantation.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060201
Title: Procedural success and 30 day outcomes between CYPHER and TAXUS stent implantation for the treatment of bifurcation lesions--a single-center experience.
Journal: The Journal of invasive cardiology 20060201
Title: mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt.
Journal: Cancer research 20060201
Title: Sirolimus-itraconazole interaction in a hematopoietic stem cell transplant recipient.
Journal: Pharmacotherapy 20060201
Title: Phase 1 trial of gefitinib plus sirolimus in adults with recurrent malignant glioma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060201
Title: Percutaneous vascular interventions in the superficial femoral artery. A review.
Journal: Minerva cardioangiologica 20060201
Title: TORgeting oncogene addiction for cancer therapy.
Journal: Cancer cell 20060201
Title: Sirolimus-versus paclitaxel-eluting stents: a comparison of two consecutive series in routine clinical practice.
Journal: Journal of interventional cardiology 20060201
Title: Editorial comment: which is the preferred drug-eluting stent?
Journal: Journal of interventional cardiology 20060201
Title: Contemporary treatment of coronary bifurcations with drug-eluting stent: part II.
Journal: Journal of interventional cardiology 20060201
Title: TCT 2005 late-breaking trials promise to influence practice patterns.
Journal: Journal of interventional cardiology 20060201
Title: [Progress in therapeutic strategy for renal cell carcinoma].
Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20060201
Title: Dutasteride, cantharidin, atopiclair, cetuximab, sirolimus, AC-11 and dimericine reviewed in brief.
Journal: Journal of drugs in dermatology : JDD 20060201
Title: Cryptogenic organizing pneumonia associated with Pneumocystis carinii infection and sirolimus therapy in a renal transplant patient.
Journal: Australasian radiology 20060201
Title: Safety and long-term efficacy of sirolimus eluting stent in ST-elevation acute myocardial infarction: the REAL (Registro REgionale AngiopLastiche Emilia-Romagna) registry.
Journal: Cardiovascular drugs and therapy 20060201
Title: [Insulin-dependent. Rapamycin-resistant?].
Journal: Revista espanola de cardiologia 20060201
Title: [Efficacy of sirolimus-eluting stents in diabetics with complex coronary lesions].
Journal: Revista espanola de cardiologia 20060201
Title: [Comparison of Rapamycin and Paclitaxel eluting stent in patients with multi-vessel coronary disease].
Journal: Zhonghua xin xue guan bing za zhi 20060201
Title: [Coronary artery atherosclerotic plaque and stent visualizations by optical coherence tomography].
Journal: Zhonghua xin xue guan bing za zhi 20060201
Title: [Effect of inhibitors of signal transducer and activator of transcription-1/3 on expression of tumor necrosis factor-alpha induced by high mobility group box-1 protein inflammatory response in rat peritoneal macrophages].
Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20060201
Title: Targeting mTOR signaling for lung cancer therapy.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20060201
Title: mTOR signaling: implications for cancer and anticancer therapy.
Journal: British journal of cancer 20060130
Title: Delayed strut fracture of sirolimus-eluting stent: a significant problem or an occasional observation?
Journal: International journal of cardiology 20060126
Title: Late stent malapposition after drug-eluting stent implantation: an intravascular ultrasound analysis with long-term follow-up.
Journal: Circulation 20060124
Title: One-year clinical outcomes of Chinese sirolimus-eluting stent in the treatment of unselected patients with coronary artery disease.
Journal: Chinese medical journal 20060120
Title: Randomized trial of a nonpolymer-based rapamycin-eluting stent versus a polymer-based paclitaxel-eluting stent for the reduction of late lumen loss.
Journal: Circulation 20060117
Title: The Stenting Coronary Arteries in Non-stress/benestent Disease (SCANDSTENT) trial.
Journal: Journal of the American College of Cardiology 20060117
Title: Hamartin, the tuberous sclerosis complex 1 gene product, interacts with polo-like kinase 1 in a phosphorylation-dependent manner.
Journal: Human molecular genetics 20060115
Title: Thrombotic microangiopathy after lung transplantation.
Journal: Transplantation 20060115
Title: Rapamycin prolongs susceptibility of responding T cells to tolerance induction by CD8+ veto cells.
Journal: Transplantation 20060115
Title: Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice.
Journal: Cancer research 20060115
Title: Rapamycin disrupts cyclin/cyclin-dependent kinase/p21/proliferating cell nuclear antigen complexes and cyclin D1 reverses rapamycin action by stabilizing these complexes.
Journal: Cancer research 20060115
Title: Early outcome of treatment of ostial de novo left anterior descending coronary artery lesions with drug-eluting stents.
Journal: The American journal of cardiology 20060115
Title: Intravascular ultrasound characterization of the 'black hole' phenomenon after drug-eluting stent implantation.
Journal: The American journal of cardiology 20060115
Title: Novel roles of Akt and mTOR in suppressing TGF-beta/ALK5-mediated Smad3 activation.
Journal: The EMBO journal 20060111
Title: In vitro release of the mTOR inhibitor rapamycin from poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20060110
Title: Phosphoinositide 3-kinase: from viral oncoprotein to drug target.
Journal: Virology 20060105
Title: Comparison of short- and mid-term outcomes between CYPHER and TAXUS stents in patients with complex lesions of the coronary arteries.
Journal: Chinese medical journal 20060105
Title: Thrombosis after implantation of drug-eluting stents.
Journal: JAMA 20060104
Title: Are drug-eluting stents the preferred treatment for multivessel coronary artery disease?
Journal: Journal of the American College of Cardiology 20060103
Title: Hypersensitivity cases associated with drug-eluting coronary stents: a review of available cases from the Research on Adverse Drug Events and Reports (RADAR) project.
Journal: Journal of the American College of Cardiology 20060103
Title: Allergic reactions after the implantation of drug-eluting stents: is it the pill or the polymer?
Journal: Journal of the American College of Cardiology 20060103
Title: Coronary stent thrombosis in the current drug-eluting stent era: insights from the ERACI III trial.
Journal: Journal of the American College of Cardiology 20060103
Title: Drug-eluting stent thrombosis: a pooled analysis.
Journal: Journal of the American College of Cardiology 20060103
Title: Cost effectiveness of drug eluting coronary artery stenting in a UK setting: cost-utility study.
Journal: Heart (British Cardiac Society) 20060101
Title: N-acetyl-cysteine abolishes hydrogen peroxide-induced modification of eukaryotic initiation factor 4F activity via distinct signalling pathways.
Journal: Cellular signalling 20060101
Title: Enhanced cytotoxicity induced by gefitinib and specific inhibitors of the Ras or phosphatidyl inositol-3 kinase pathways in non-small cell lung cancer cells.
Journal: International journal of cancer 20060101
Title: Early elevation of interleukin-1beta and interleukin-6 levels after bare or drug-eluting stent implantation in patients with stable angina.
Journal: Thrombosis research 20060101
Title: Mammalian target of rapamycin is required for thrombopoietin-induced proliferation of megakaryocyte progenitors.
Journal: Stem cells (Dayton, Ohio) 20060101
Title: Dimerizer regulation of AADC expression and behavioral response in AAV-transduced 6-OHDA lesioned rats.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20060101
Title: Patterns of pulmonary complications associated with sirolimus.
Journal: Respiration; international review of thoracic diseases 20060101
Title: Rapamycin control of transgene expression from a single AAV vector in mouse salivary glands.
Journal: Gene therapy 20060101
Title: Social inhibition modulates the effect of negative emotions on cardiac prognosis following percutaneous coronary intervention in the drug-eluting stent era.
Journal: European heart journal 20060101
Title: Indication of long-term endothelial dysfunction after sirolimus-eluting stent implantation.
Journal: European heart journal 20060101
Title: Coronary endothelial dysfunction following sirolimus-eluting stent placement: should we worry about it?
Journal: European heart journal 20060101
Title: Sirolimus PK trial: a pharmacokinetic study of the sirolimus-eluting Bx velocity stent in patients with de novo coronary lesions.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060101
Title: Heme oxygenase-1 mediates the protective effects of rapamycin in monocrotaline-induced pulmonary hypertension.
Journal: Laboratory investigation; a journal of technical methods and pathology 20060101
Title: Marked erythrocyte microcytosis under primary immunosuppression with sirolimus.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20060101
Title: Cardiac transplantation without calcineurin inhibitors. Sirolimus as first immunosuppressive line. Based on one case.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20060101
Title: Images in cardiology. Acute recoil in sirolimus eluting stent: real time, in vivo assessment with optical coherence tomography.
Journal: Heart (British Cardiac Society) 20060101
Title: From Rapa Nui to rapamycin: targeting PI3K/Akt/mTOR for cancer therapy.
Journal: Expert review of anticancer therapy 20060101
Title: Efficacy of sirolimus-eluting stents compared with bare metal stents for saphenous vein graft intervention.
Journal: The American journal of cardiology 20060101
Title: Natural killer T-cells participate in rejection of islet allografts in the liver of mice.
Journal: Diabetes 20060101
Title: Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance.
Journal: Diabetes 20060101
Title: Atrophic remodeling of the transplanted rat heart.
Journal: Cardiology 20060101
Title: Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways.
Journal: Cancer research 20060101
Title: A comparative study of sirolimus tablet versus oral solution for prophylaxis of acute renal allograft rejection.
Journal: Journal of clinical pharmacology 20060101
Title: Relationship of cyclosporin and sirolimus blood concentrations regarding the incidence and severity of hyperlipidemia after kidney transplantation.
Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20060101
Title: One year follow-up of sirolimus-eluting stent in a cardiac post-transplant patient.
Journal: The Journal of invasive cardiology 20060101
Title: Kidney cancer: identification of novel targets for therapy.
Journal: Kidney international 20060101
Title: Synergistic suppression of rat neointimal hyperplasia by rapamycin and imatinib mesylate: implications for the prevention of accelerated arteriosclerosis.
Journal: Journal of vascular research 20060101
Title: Structure-activity relationship for noncoplanar polychlorinated biphenyl congeners toward the ryanodine receptor-Ca2+ channel complex type 1 (RyR1).
Journal: Chemical research in toxicology 20060101
Title: Hypoxia-inducible factor-1alpha polymorphisms and TSC1/2 mutations are complementary in head and neck cancers.
Journal: Molecular cancer 20060101
Title: Tolerance induction by third-party 'off-the-shelf' CD4+CD25+ Treg cells.
Journal: Experimental hematology 20060101
Title: Accounting for strain-specific differences during RTG target gene regulation in Saccharomyces cerevisiae.
Journal: FEMS yeast research 20060101
Title: Rapamycin analogs with differential binding specificity permit orthogonal control of protein activity.
Journal: Chemistry & biology 20060101
Title: Apoptosis of allospecifically activated human helper T cells is blocked by calcineurin inhibition.
Journal: Transplant immunology 20060101
Title: Everolimus versus azathioprine in maintenance lung transplant recipients: an international, randomized, double-blind clinical trial.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060101
Title: Evaluation of the cost effectiveness of sirolimus versus tacrolimus for immunosuppression following renal transplantation in the UK.
Journal: PharmacoEconomics 20060101
Title: NMR assignment of the mTOR domain responsible for rapamycin binding.
Journal: Journal of biomolecular NMR 20060101
Title: Pulsed immunosuppression with everolimus and anti-alphabeta T-cell receptor: laryngeal allograft preservation at six months.
Journal: The Annals of otology, rhinology, and laryngology 20060101
Title: [In-hospital and remote results of the use of sirolimus coated coronary stent CYPHER].
Journal: Kardiologiia 20060101
Title: Successful reversal of acute vascular rejection and cyclosporine-associated nephrotoxicity in renal allograft with combined sirolimus and mycophenolate mofetil as immunotherapy.
Journal: Transplantation proceedings 20060101
Title: Individualization of immunosuppressive therapy. II. Sirolimus as a less nephrotoxic alternative to calcineurin inhibitors.
Journal: Transplantation proceedings 20060101
Title: Economic evaluation of sirolimus-based immunosuppressive regimens in kidney graft recipients.
Journal: Transplantation proceedings 20060101
Title: High-performance liquid chromatography versus immunoassay for the measurement of sirolimus: comparison of two methods.
Journal: Transplantation proceedings 20060101
Title: Conversion to sirolimus from cyclosporine may induce nephrotic proteinuria and progressive deterioration of renal function in chronic allograft nephropathy patients.
Journal: Transplantation proceedings 20060101
Title: Hypoxia-inducible factor 1alpha (HIF-1alpha) correlated with tumor growth and apoptosis in ovarian cancer.
Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101
Title: Thrombosis after implantation of drug-eluting stents.
Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20060101
Title: Efficacy of polyphenon E, red ginseng, and rapamycin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice.
Journal: Neoplasia (New York, N.Y.) 20060101
Title: Early steroid withdrawal after renal transplantation.
Journal: Nephrology nursing journal : journal of the American Nephrology Nurses' Association 20060101
Title: [Rapamycine and mTOR inhibitors: from bench to bedside].
Journal: Annales de biologie clinique 20060101
Title: mTOR inhibitors.
Journal: Clinical advances in hematology & oncology : H&O 20060101
Title: Mutual information-based feature selection in studying perturbation of dendritic structure caused by TSC2 inactivation.
Journal: Neuroinformatics 20060101
Title: Everolimus: a review of its use in renal and cardiac transplantation.
Journal: Drugs 20060101
Title: The engineering of endovascular stent technology: a review.
Journal: Vascular and endovascular surgery 20060101
Title: [Stent therapy with diabetic patients who have coronary artery disease].
Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20060101
Title: Evaluation of an immunoassay of whole blood sirolimus in pediatric transplant patients in comparison with high-performance liquid chromatography/tandem mass spectrometry.
Journal: Clinical chemistry and laboratory medicine 20060101
Title: The paclitaxel-eluting stent in percutaneous coronary intervention: Part II. Comparison with the sirolimus-eluting stent, economics, and unanswered questions.
Journal: Cardiology in review 20060101
Title: [Sustained rapamycin drug delivery system in prevention of high risk corneal allograft rejection and neovascularization in rabbits].
Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20060101
Title: The drug-eluting stent dilemma: comparing the effectiveness of Cypher versus Taxus.
Journal: Journal of cardiovascular medicine (Hagerstown, Md.) 20060101
Title: Sirolimus: friend or foe?
Journal: Respiration; international review of thoracic diseases 20060101
Title: Rheb activation of mTOR and S6K1 signaling.
Journal: Methods in enzymology 20060101
Title: The paradox of sirolimus-induced immunosuppression and tumor control.
Journal: Dermatology (Basel, Switzerland) 20060101
Title: Posttransplant Kaposi's sarcoma restricted to the site of a previous deep venous thrombosis: abrupt onset after withdrawal of sirolimus.
Journal: Dermatology (Basel, Switzerland) 20060101
Title: Cost effectiveness of the sirolimus-eluting stent in high-risk patients in Canada: an analysis from the C-SIRIUS trial.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101
Title: Renal function in renal or liver transplant recipients after conversion from a calcineurin inhibitor to sirolimus.
Journal: Clinical transplantation 20060101
Title: Role of FK778 alone or in combination with tacrolimus or mTOR inhibitors as an immunomodulator of immunofunctions: in vitro evaluation of T cell proliferation and the expression of lymphocyte surface antigens.
Journal: International journal of immunopathology and pharmacology 20060101
Title: Cluster analysis of protein array results via similarity of Gene Ontology annotation.
Journal: BMC bioinformatics 20060101
Title: Cost-effectiveness of sirolimus therapy with early cyclosporin withdrawal vs. long-term cyclosporin therapy in Australia.
Journal: Clinical transplantation 20060101
Title: The mTOR inhibitor rapamycin down-regulates the expression of the ubiquitin ligase subunit Skp2 in breast cancer cells.
Journal: Breast cancer research : BCR 20060101
Title: Role of cytomegalovirus and Epstein-Barr virus in patients with de novo colon cancer after renal transplantation.
Journal: Tumori 20060101
Title: Protective roles for induction of autophagy in multiple proteinopathies.
Journal: Autophagy 20060101
Title: Lysosomal turnover of GABARAP-phospholipid conjugate is activated during differentiation of C2C12 cells to myotubes without inactivation of the mTor kinase-signaling pathway.
Journal: Autophagy 20060101
Title: Deletion of HOG1 leads to Osmosensitivity in starvation-induced, but not rapamycin-dependent Atg8 degradation and proteolysis: further evidence for different regulatory mechanisms in yeast autophagy.
Journal: Autophagy 20060101
Title: Late acute thrombosis after implantation of sirolimus-eluting stent to treat in-stent restenosis.
Journal: Acute cardiac care 20060101
Title: [Sirolimus-induced onychopathy in renal transplant recipients].
Journal: Annales de dermatologie et de venereologie 20060101
Title: [Study of drugs against neoplastic metastasis].
Journal: Magyar onkologia 20060101
Title: The mTOR pathway in breast cancer.
Journal: Journal of mammary gland biology and neoplasia 20060101
Title: Conversion to sirolimus in pediatric renal transplantation recipients.
Journal: Transplantation proceedings 20060101
Title: Validation of using gene expression in mononuclear cells as a marker for hepatic cholesterol metabolism.
Journal: Lipids in health and disease 20060101
Title: Effect of cyclosporine and sirolimus on the expression of connective tissue growth factor in rat experimental chronic nephrotoxicity.
Journal: American journal of nephrology 20060101
Title: Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels.
Journal: BMC cell biology 20060101
Title: Is sirolimus better than paclitaxel? A review of the comparative data on drug-eluting stents.
Journal: Cardiovascular revascularization medicine : including molecular interventions 20060101
Title: Optimal dosing and duration of oral everolimus to inhibit in-stent neointimal growth in rabbit iliac arteries.
Journal: Cardiovascular revascularization medicine : including molecular interventions 20060101
Title: Morphoproteomic and pharmacoproteomic rationale for mTOR effectors as therapeutic targets in head and neck squamous cell carcinoma.
Journal: Annals of clinical and laboratory science 20060101
Title: Morphoproteomic and molecular concomitants of an overexpressed and activated mTOR pathway in renal cell carcinomas.
Journal: Annals of clinical and laboratory science 20060101
Title: Evaluation of a microparticle enzyme immunoassay for the measurement of sirolimus in whole blood (Abbott IMx sirolimus).
Journal: Clinical laboratory 20060101
Title: Oral immunosuppressive drugs.
Journal: Clinical medicine (London, England) 20060101
Title: Excellent clinical outcomes in primary kidney transplant recipients treated with steroid-free maintenance immunosuppression.
Journal: Clinical transplantation 20060101
Title: [Comparison of high-resolution liquid chromatography versus microparticle enzyme immunoassay for the measurement of sirolimus levels in renal transplantation].
Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20060101
Title: Cardiac overexpression of metallothionein rescues chronic alcohol intake-induced cardiomyocyte dysfunction: role of Akt, mammalian target of rapamycin and ribosomal p70s6 kinase.
Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20060101
Title: Sirolimus population pharmacokinetic/pharmacogenetic analysis and bayesian modelling in kidney transplant recipients.
Journal: Clinical pharmacokinetics 20060101
Title: Method development and validation for zotarolimus concentration determination in stented swine arteries by liquid chromatography/tandem mass spectrometry detection.
Journal: Rapid communications in mass spectrometry : RCM 20060101
Title: Successive, rapid recurrences of in-stent restenoses in a woman with angina pectoris.
Journal: Internal medicine (Tokyo, Japan) 20060101
Title: Drug-eluting stents.
Journal: Archivos de cardiologia de Mexico 20060101
Title: The role and value of sirolimus administration in kidney and liver transplantation.
Journal: Clinical transplantation 20060101
Title: Sirolimus-induced interstitial pneumonitis.
Journal: Journal of postgraduate medicine 20060101
Title: Switching from HPLC/UV to MEIA for whole blood sirolimus quantitation: comparison of methods.
Journal: Journal of clinical laboratory analysis 20060101
Title: Regulating cell surface glycosylation with a small-molecule switch.
Journal: Methods in enzymology 20060101
Title: Subacute thrombosis following implantation of zotarolimus-eluting stent.
Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20060101
Title: Sirolimus-associated proteinuria and renal dysfunction.
Journal: Drug safety 20060101
Title: [Efficacy of the use of sirolimus covered stents in the treatment of diffuse atherosclerotic lesions of coronary arteries].
Journal: Kardiologiia 20060101
Title: Targeting mTOR for cancer treatment.
Journal: Advances in experimental medicine and biology 20060101
Title: Promoting vascular regeneration as an alternative to conventional angioplasty-based intervention.
Journal: Endothelium : journal of endothelial cell research 20060101
Title: Comparison of paclitaxel-eluting stent and sirolimus-eluting stent expansion at incremental delivery pressures.
Journal: Cardiovascular revascularization medicine : including molecular interventions 20060101
Title: Resolution of neurotoxicity and beta-cell toxicity in an islet transplant recipient following substitution of tacrolimus with MMF.
Journal: Cell transplantation 20060101
Title: Thrombosis of drug-eluting stents: fact or fiction?
Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20060101
Title: Clinical benefits of drug-eluting stents: results from RAVEL and beyond.
Journal: The Journal of cardiovascular nursing 20060101
Title: [Lung toxicity induced by rapamycin].
Journal: Revista portuguesa de pneumologia 20060101
Title: Mammalian target of rapamycin is a promising target for novel therapeutic strategy against cancer.
Journal: Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20060101
Title: [Use of 'Cypher' sirolimus-eluting stents in coronary heart disease patients with different types of coronary arterial lesions].
Journal: Vestnik rentgenologii i radiologii 20060101
Title: Contribution of transplantation to the development of medical science. How transplantation contributes to the world of medicine.
Journal: Annals of transplantation 20060101
Title: Sirolimus-eluting stents. (The results of the five-year use for the treatment of coronary artery disease).
Journal: Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20060101
Title: A prospective, open-label trial of sirolimus in the treatment of focal segmental glomerulosclerosis.
Journal: Clinical journal of the American Society of Nephrology : CJASN 20060101
Title: Preface. Sirolimus and kidney transplantation.
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101
Title: Current trends in immunosuppression.
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101
Title: Transplantation and tumors.
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101
Title: Sirolimus, the first mTOR inhibitor.
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101
Title: Sirolimus use in de 'novo renal' transplantation.
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101
Title: Conversion to sirolimus.
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101
Title: Handling sirolimus in clinical practice. Spanish Nephrology Society.
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101
Title: [Long-term clinical efficiency of endovascular treatment using Cypher rapamycin-eluting stents in patients with coronary heart disease].
Journal: Vestnik rentgenologii i radiologii 20060101
Title: Anesthetic rejection followed by surgical salvage.
Journal: Clinical transplants 20060101
Title: Cyclosporine A, FK-506, 40-0-[2-hydroxyethyl]rapamycin and mycophenolate mofetil inhibit proliferation of human intrahepatic biliary epithelial cells in vitro.
Journal: World journal of gastroenterology 20051228
Title: Apolipoprotein E genotypes as predictors of high-risk groups for developing hyperlipidemia in kidney transplant recipients undergoing sirolimus treatment.
Journal: Transplantation 20051227
Title: Sirolimus use and de novo minimal change nephropathy following renal transplantation.
Journal: Transplantation 20051227
Title: mTOR regulates cell survival after etoposide treatment in primary AML cells.
Journal: Blood 20051215
Title: Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFkappaB activation in vivo.
Journal: Free radical biology & medicine 20051215
Title: Comparison between sirolimus-eluting stents and intracoronary catheter-based beta radiation for the treatment of in-stent restenosis.
Journal: The American journal of cardiology 20051215
Title: Clinical outcome following aleatory implantation of paclitaxel-eluting or sirolimus-eluting stents in complex coronary lesions.
Journal: The American journal of cardiology 20051215
Title: Low-dose radiation plus rapamycin promotes long-term bone marrow chimerism.
Journal: Transplantation 20051215
Title: Conversion from cyclosporine to sirolimus in stable renal transplant recipients.
Journal: Transplantation 20051215
Title: Control of dendritic arborization by the phosphoinositide-3'-kinase-Akt-mammalian target of rapamycin pathway.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20051207
Title: Local and systemic drug competition in drug-eluting stent tissue deposition properties.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20051205
Title: Superiority of sirolimus eluting stent compared with intracoronary beta radiation for treatment of in-stent restenosis: a matched comparison.
Journal: Heart (British Cardiac Society) 20051201
Title: Negative regulation of melanogenesis by phospholipase D1 through mTOR/p70 S6 kinase 1 signaling in mouse B16 melanoma cells.
Journal: Journal of cellular physiology 20051201
Title: mTOR function in skeletal muscle hypertrophy: increased ribosomal RNA via cell cycle regulators.
Journal: American journal of physiology. Cell physiology 20051201
Title: Enhancement of translation elongation in neurons by brain-derived neurotrophic factor: implications for mammalian target of rapamycin signaling.
Journal: Journal of neurochemistry 20051201
Title: Rapamycin analogs with reduced systemic exposure.
Journal: Bioorganic & medicinal chemistry letters 20051201
Title: Synergistic effect of targeting mTOR by rapamycin and depleting ATP by inhibition of glycolysis in lymphoma and leukemia cells.
Journal: Leukemia 20051201
Title: Noninvasive imaging of protein-protein interactions from live cells and living subjects using bioluminescence resonance energy transfer.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051201
Title: S6 kinase 2 potentiates interleukin-3-driven cell proliferation.
Journal: Journal of leukocyte biology 20051201
Title: Rapamycin for treatment of chronic allograft nephropathy in renal transplant patients.
Journal: Journal of the American Society of Nephrology : JASN 20051201
Title: Vascular response to sirolimus-eluting stents delivered with a nonaggressive implantation technique: comparison of intravascular ultrasound results from the multicenter, randomized E-SIRIUS, and SIRIUS trials.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20051201
Title: In smooth muscle, FK506-binding protein modulates IP3 receptor-evoked Ca2+ release by mTOR and calcineurin.
Journal: Journal of cell science 20051201
Title: Drug-eluting stents for the treatment of intracranial atherosclerosis: initial experience and midterm angiographic follow-up.
Journal: Stroke 20051201
Title: Pilot study with an intensified oral sirolimus regimen for the prevention of in-stent restenosis in de novo lesions: a serial intravascular ultrasound study.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20051201
Title: Pharmacokinetics of sirolimus (rapamycin) in subjects with mild to moderate hepatic impairment.
Journal: Journal of clinical pharmacology 20051201
Title: Inhibition of target of rapamycin signaling by rapamycin in the unicellular green alga Chlamydomonas reinhardtii.
Journal: Plant physiology 20051201
Title: Mechanisms of everolimus-induced glomerulosclerosis after glomerular injury in the rat.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051201
Title: Influence of co-medication with sirolimus or cyclosporine on mycophenolic acid pharmacokinetics in kidney transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051201
Title: Alemtuzumab induction and sirolimus plus mycophenolate mofetil maintenance for CNI and steroid-free kidney transplant immunosuppression.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051201
Title: Calcineurin inhibitor withdrawal from sirolimus-based therapy in kidney transplantation: a systematic review of randomized trials.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051201
Title: Development and validation of a high-throughput assay for quantification of the proliferation inhibitor ABT-578 using LC/LC-MS/MS in blood and tissue samples.
Journal: Therapeutic drug monitoring 20051201
Title: Technology Insight: an overview of research in drug-eluting stents.
Journal: Nature clinical practice. Cardiovascular medicine 20051201
Title: Thrombotic microangiopathy in marginal kidneys after sirolimus use.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20051201
Title: Biochemical monitoring of mTOR inhibitor-based immunosuppression following kidney transplantation: a novel approach for tailored immunosuppressive therapy.
Journal: Kidney international 20051201
Title: Rapamycin worsens renal function and intratubular cast formation in protein overload nephropathy.
Journal: Kidney international 20051201
Title: Sirolimus-induced interstitial pneumonitis in a renal transplant patient.
Journal: Respiratory care 20051201
Title: Drug-eluting coronary stents.
Journal: The New England journal of medicine 20051201
Title: Time course of release of inflammatory markers after coronary stenting: comparison between bare metal stent and sirolimus-eluting stent.
Journal: Coronary artery disease 20051201
Title: Drug-eluting coronary stents.
Journal: The New England journal of medicine 20051201
Title: Drug-eluting coronary stents.
Journal: The New England journal of medicine 20051201
Title: Drug-eluting coronary stents.
Journal: The New England journal of medicine 20051201
Title: Drug-eluting coronary stents.
Journal: The New England journal of medicine 20051201
Title: Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells.
Journal: Cancer research 20051201
Title: Cypher versus taxus: are there differences?
Journal: Journal of interventional cardiology 20051201
Title: Treatment of unprotected left main coronary artery stenosis in the drug-eluting stent era.
Journal: Journal of interventional cardiology 20051201
Title: Should degenerated saphenous vein grafts routinely be sealed with drug-eluting stents?
Journal: Journal of interventional cardiology 20051201
Title: Immunosuppressive treatment and progression of histologic lesions in kidney allografts.
Journal: Kidney international. Supplement 20051201
Title: The hypoxic microenvironment of the skin contributes to Akt-mediated melanocyte transformation.
Journal: Cancer cell 20051201
Title: Outcome of percutaneous hybrid coronary revascularization: bare metal stents jeopardize the benefit of sirolimus-eluting stents in the real world.
Journal: The Canadian journal of cardiology 20051201
Title: Sirolimus: its role in nephrology.
Journal: Nephrology (Carlton, Vic.) 20051201
Title: Sirolimus-eluting versus bare stents for bailout after suboptimal infrapopliteal angioplasty for critical limb ischemia: 6-month angiographic results from a nonrandomized prospective single-center study.
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20051201
Title: Sirolimus in cardiac transplantation: use as a primary immunosuppressant in calcineurin inhibitor-induced nephrotoxicity.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20051201
Title: Bone morphogenetic protein-2-induced transformation involves the activation of mammalian target of rapamycin.
Journal: Molecular cancer research : MCR 20051201
Title: Everolimus (certican) in heart transplantation: optimizing renal function through minimizing cyclosporine exposure.
Journal: Transplantation proceedings 20051201
Title: Sirolimus conversion after liver transplantation: improvement in measured glomerular filtration rate after 2 years.
Journal: Transplantation proceedings 20051201
Title: Late acute cardiac allograft rejection: new therapeutic options?
Journal: Transplantation proceedings 20051201
Title: Late expression of nitroreductase in an oncolytic adenovirus sensitizes colon cancer cells to the prodrug CB1954.
Journal: Human gene therapy 20051201
Title: Biomarkers for toxicodynamic monitoring of immunosuppressants: NMR-based quantitative metabonomics of the blood.
Journal: Therapeutic drug monitoring 20051201
Title: Complete regression of visceral Kaposi's sarcoma after conversion to sirolimus.
Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20051201
Title: [The safety and efficacy of Cypher drug-eluting stent: results from a six months follow-up study in patients with ST-segment elevation myocardial infarction].
Journal: Zhonghua xin xue guan bing za zhi 20051201
Title: Drug-eluting stent: a review and update.
Journal: Vascular health and risk management 20051201
Title: Glutamatergic regulation of the p70S6 kinase in primary mouse neurons.
Journal: The Journal of biological chemistry 20051118
Title: mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events.
Journal: Cell 20051118
Title: Comparison of effects of drug-eluting stents versus bare metal stents on plasma C-reactive protein levels.
Journal: The American journal of cardiology 20051115
Title: Impact of diabetes mellitus on angiographic and clinical outcomes in the drug-eluting stents era.
Journal: The American journal of cardiology 20051115
Title: Effect of sirolimus-eluting stent in diabetic patients with small coronary arteries (a SES-SMART substudy).
Journal: The American journal of cardiology 20051115
Title: Impact of asymmetric stent expansion on neointimal hyperplasia following sirolimus-eluting stent implantation.
Journal: The American journal of cardiology 20051115
Title: Proteinuria following a switch from calcineurin inhibitors to sirolimus.
Journal: Transplantation 20051115
Title: Superior outcomes in renal transplantation after early cyclosporine withdrawal and sirolimus maintenance therapy, regardless of baseline renal function.
Journal: Transplantation 20051115
Title: Anemia after late introduction of sirolimus may correlate with biochemical evidence of a chronic inflammatory state.
Journal: Transplantation 20051115
Title: Sirolimus monotherapy: feasible immunosuppression for long-term follow-up of kidney transplantation--a pilot experience.
Journal: Transplantation 20051115
Title: Post-transplantation proteinuria and sirolimus.
Journal: The New England journal of medicine 20051110
Title: Drug-eluting stents: sirolimus and paclitaxel differentially affect cultured cells and injured arteries.
Journal: European journal of pharmacology 20051107
Title: A systematic review and economic analysis of drug-eluting coronary stents available in Australia.
Journal: The Medical journal of Australia 20051107
Title: PTEN-induction in U251 glioma cells decreases the expression of insulin-like growth factor binding protein-2.
Journal: Biochemical and biophysical research communications 20051104
Title: A novel drug-eluting stent spray-coated with multi-layers of collagen and sirolimus.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20051102
Title: Role of oral rapamycin to prevent restenosis in patients with de novo lesions undergoing coronary stenting: results of the Argentina single centre study (ORAR trial).
Journal: Heart (British Cardiac Society) 20051101
Title: Reduced cardiac hypertrophy in toll-like receptor 4-deficient mice following pressure overload.
Journal: Cardiovascular research 20051101
Title: Long-term results in renal transplant patients with allograft dysfunction after switching from calcineurin inhibitors to sirolimus.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20051101
Title: LDL-cholesterol predicts negative coronary artery remodelling in diabetic patients: an intravascular ultrasound study.
Journal: European heart journal 20051101
Title: Protein turnover in cardiac cell growth and survival.
Journal: Cardiovascular research 20051101
Title: Ca2+-dependent reduction of IK1 in rat ventricular cells: a novel paradigm for arrhythmia in heart failure?
Journal: Cardiovascular research 20051101
Title: Protective effect of calcineurin inhibitors on acoustic injury of the cochlea.
Journal: Hearing research 20051101
Title: Sirolimus-induced ulceration of the small bowel in islet transplant recipients: report of two cases.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051101
Title: Impairment of renal function after islet transplant alone or islet-after-kidney transplantation using a sirolimus/tacrolimus-based immunosuppressive regimen.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20051101
Title: Sirolimus-associated hepatotoxicity in the kidney graft recipient.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20051101
Title: Inflammation and caspase activation in long-term renal ischemia/reperfusion injury and immunosuppression in rats.
Journal: Kidney international 20051101
Title: Relationships between sirolimus dosing, concentration and outcomes in renal transplant recipients.
Journal: British journal of clinical pharmacology 20051101
Title: Trimethoprim-sulphamethoxazole does not affect the pharmacokinetics of sirolimus in renal transplant recipients.
Journal: British journal of clinical pharmacology 20051101
Title: Ex vivo rapamycin generates donor Th2 cells that potently inhibit graft-versus-host disease and graft-versus-tumor effects via an IL-4-dependent mechanism.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20051101
Title: Ng-MIP, a surface-exposed lipoprotein of Neisseria gonorrhoeae, has a peptidyl-prolyl cis/trans isomerase (PPIase) activity and is involved in persistence in macrophages.
Journal: Molecular microbiology 20051101
Title: Paclitaxel-eluting stents in coronary artery disease.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20051101
Title: Inflammatory reaction after sirolimus-eluting stent implant.
Journal: The Annals of thoracic surgery 20051101
Title: Impact of intravascular ultrasound lesion characteristics on neointimal hyperplasia following sirolimus-eluting stent implantation.
Journal: The American journal of cardiology 20051101
Title: Predictors of edge stenosis following sirolimus-eluting stent deployment (a quantitative intravascular ultrasound analysis from the SIRIUS trial).
Journal: The American journal of cardiology 20051101
Title: Elevated glucose activates protein synthesis in cultured cardiac myocytes.
Journal: Metabolism: clinical and experimental 20051101
Title: Darbepoetin alfa treatment for post-renal transplantation anemia during pregnancy.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20051101
Title: Evaluation of four-year coronary artery response after sirolimus-eluting stent implantation using serial quantitative intravascular ultrasound and computer-assisted grayscale value analysis for plaque composition in event-free patients.
Journal: Journal of the American College of Cardiology 20051101
Title: Treatment of in-stent restenosis with sirolimus-eluting-stents -- a six month clinical and angiographic follow-up.
Journal: Zeitschrift fur Kardiologie 20051101
Title: Sirolimus-eluting stent treatment for complex proximal left anterior descending artery stenoses: 7-month clinical and angiographic results.
Journal: The Journal of invasive cardiology 20051101
Title: Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck.
Journal: Cancer research 20051101
Title: Rapamycin-coated expanded polytetrafluoroethylene bypass grafts exhibit decreased anastomotic neointimal hyperplasia in a porcine model.
Journal: Journal of vascular surgery 20051101
Title: Improvement of renal dysfunction by conversion from calcineurin inhibitors to sirolimus after heart transplantation.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20051101
Title: Mammalian target of rapamycin as a therapeutic target in leukemia.
Journal: Current molecular medicine 20051101
Title: Mammalian target of rapamycin promotes vincristine resistance through multiple mechanisms independent of maintained glycolytic rate.
Journal: Molecular cancer research : MCR 20051101
Title: [Six-month intravascular ultrasound follow-up of coronary bifurcation lesions treated with rapamycin-eluting stents: technical considerations].
Journal: Revista espanola de cardiologia 20051101
Title: [Coronary artery aneurysm one year and five months after sirolimus-eluting stent placement].
Journal: Arquivos brasileiros de cardiologia 20051101
Title: [Sirolimus-eluting vs paclitaxel-eluting stents -- the trials confirm differences in clinical outcome].
Journal: Kardiologia polska 20051101
Title: Evaluation of the cost-effectiveness of sirolimus versus cyclosporin for immunosuppression after renal transplantation in the United Kingdom.
Journal: Clinical therapeutics 20051101
Title: Individualization of immunosuppressive therapy: I. Sirolimus improves outcomes in African-American renal transplant recipients.
Journal: Transplantation proceedings 20051101
Title: Rapamycin at six years can exhibit normal renal function without proteinuria or neoplasia after renal transplantation. A single-center experience.
Journal: Transplantation proceedings 20051101
Title: Evolution of proteinuria after conversion from calcineurin inhibitors (CNI) to sirolimus (SRL) in renal transplant patients: a multicenter study.
Journal: Transplantation proceedings 20051101
Title: Efficacy of conversion to sirolimus in posttransplantation Kaposi's sarcoma.
Journal: Transplantation proceedings 20051101
Title: Rapamycin in lung transplantation.
Journal: Transplantation proceedings 20051101
Title: Sirolimus as an alternative to anticalcineurin therapy in heart transplantation: experience of a single center.
Journal: Transplantation proceedings 20051101
Title: [Drug eluting stents in 2005: have the initial expectations been met?].
Journal: Annales de cardiologie et d'angeiologie 20051101
Title: [Comparison of the effects of rapamycin-eluting stent implantation and coronary artery bypass grafting in treatment of patients with multi-vessel coronary disease].
Journal: Zhonghua yi xue za zhi 20051026
Title: RACK1 mRNA translation is regulated via a rapamycin-sensitive pathway and coordinated with ribosomal protein synthesis.
Journal: FEBS letters 20051024
Title: Protein synthesis-independent plasticity mediates rapid and precise recovery of deprived eye responses.
Journal: Neuron 20051020
Title: Impact of treatment of coronary artery disease with sirolimus-eluting stents on outcomes of diabetic and nondiabetic patients.
Journal: The American journal of cardiology 20051015
Title: Predictors of outcome after sirolimus-eluting stent implantation for complex in-stent restenosis.
Journal: The American journal of cardiology 20051015
Title: Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies.
Journal: Transplantation 20051015
Title: New-onset diabetes after kidney transplantation: an application of 2003 International Guidelines.
Journal: Transplantation 20051015
Title: Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids.
Journal: Transplantation 20051015
Title: Review of major clinical trials with mycophenolate mofetil in renal transplantation.
Journal: Transplantation 20051015
Title: The impact of mycophenolate mofetil on long-term outcomes in kidney transplantation.
Journal: Transplantation 20051015
Title: Malignancy after transplantation.
Journal: Transplantation 20051015
Title: Attenuation of insulin-stimulated insulin receptor substrate-1 serine 307 phosphorylation in insulin resistance of type 2 diabetes.
Journal: The Journal of biological chemistry 20051014
Title: Synergistic inhibition of human neuroblastoma-related angiogenesis by vinblastine and rapamycin.
Journal: Oncogene 20051013
Title: [Everolimus].
Journal: Deutsche medizinische Wochenschrift (1946) 20051007
Title: Tirofiban plus sirolimus-eluting stent vs abciximab plus bare-metal stent.
Journal: JAMA 20051005
Title: Tirofiban plus sirolimus-eluting stent vs abciximab plus bare-metal stent.
Journal: JAMA 20051005
Title: Randomized comparison of sirolimus-eluting stent versus standard stent for percutaneous coronary revascularization in diabetic patients: the diabetes and sirolimus-eluting stent (DIABETES) trial.
Journal: Circulation 20051004
Title: Differential regulation of the p70 S6 kinase pathway by interferon alpha (IFNalpha) and imatinib mesylate (STI571) in chronic myelogenous leukemia cells.
Journal: Blood 20051001
Title: Cell size reduction induced by inhibition of the mTOR/S6K-signaling pathway protects Jurkat cells from apoptosis.
Journal: Cell death and differentiation 20051001
Title: Altered centrosomes in ataxia-telangiectasia cells and rapamycin-treated Chinese hamster cells.
Journal: Environmental and molecular mutagenesis 20051001
Title: Insulin-like growth factor-I inhibits dexamethasone-induced proteolysis in cultured L6 myotubes through PI3K/Akt/GSK-3beta and PI3K/Akt/mTOR-dependent mechanisms.
Journal: The international journal of biochemistry & cell biology 20051001
Title: Combination of imatinib with rapamycin or RAD001 acts synergistically only in Bcr-Abl-positive cells with moderate resistance to imatinib.
Journal: Leukemia 20051001
Title: Rapamycin: an anti-cancer immunosuppressant?
Journal: Critical reviews in oncology/hematology 20051001
Title: T-cadherin protects endothelial cells from oxidative stress-induced apoptosis.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051001
Title: Glucose metabolism in renal transplant recipients: effect of calcineurin inhibitor withdrawal and conversion to sirolimus.
Journal: Journal of the American Society of Nephrology : JASN 20051001
Title: [Late thrombosis of a drug-eluting coronary stent after antiplatelet therapy discontinuation].
Journal: Annales francaises d'anesthesie et de reanimation 20051001
Title: Compensatory PI3-kinase/Akt/mTor activation regulates imatinib resistance development.
Journal: Leukemia 20051001
Title: Concentration-controlled use of sirolimus associated with reduced exposure of cyclosporine in black recipients of primarily living renal allograft donors: 12-month results.
Journal: Clinical transplantation 20051001
Title: Sirolimus-associated interstitial pneumonitis in solid organ transplant recipients.
Journal: Clinical transplantation 20051001
Title: The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis.
Journal: Apoptosis : an international journal on programmed cell death 20051001
Title: ISR II study: a long-term evaluation of sirolimus-eluting stent in the treatment of patients with in-stent restenotic native coronary artery lesions.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20051001
Title: Sirolimus-eluting stents: safe and effective in the treatment of in-stent restenosis.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20051001
Title: Comparison of pharmacokinetics of the sirolimus-eluting stent in Japanese patients with those in American patients.
Journal: Journal of cardiovascular pharmacology 20051001
Title: Rapamycin attenuates atherosclerotic plaque progression in apolipoprotein E knockout mice: inhibitory effect on monocyte chemotaxis.
Journal: Journal of cardiovascular pharmacology 20051001
Title: Involvement of c-Jun NH2 terminal kinase and p38MAPK in rapamycin-mediated inhibition of neointimal formation in rat carotid arteries.
Journal: Journal of cardiovascular pharmacology 20051001
Title: Sirolimus-induced thrombotic microangiopathy is associated with decreased expression of vascular endothelial growth factor in kidneys.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051001
Title: A randomized controlled trial of late conversion from CNI-based to sirolimus-based immunosuppression following renal transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051001
Title: Three-year efficacy and safety results from a study of everolimus versus mycophenolate mofetil in de novo renal transplant patients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051001
Title: Comparison of sirolimus with low-dose tacrolimus versus sirolimus-based calcineurin inhibitor-free regimen in live donor renal transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051001
Title: Hypoxia inducible factor-1: a novel target for cancer therapy.
Journal: Anti-cancer drugs 20051001
Title: Expression of proline-rich Akt-substrate PRAS40 in cell survival pathway and carcinogenesis.
Journal: Acta pharmacologica Sinica 20051001
Title: The role of therapeutic monitoring of everolimus in solid organ transplantation.
Journal: Therapeutic drug monitoring 20051001
Title: New drug-eluting stents, optimizing technique, and the problem of drug-eluting stent restenosis.
Journal: Minerva cardioangiologica 20051001
Title: Pharmacokinetic interaction between verapamil and everolimus in healthy subjects.
Journal: British journal of clinical pharmacology 20051001
Title: Thrombosis of sirolimus-eluting coronary stent in the postanesthesia care unit.
Journal: Anesthesia and analgesia 20051001
Title: Angiographic and clinical outcomes of a pharmacokinetic study of sirolimus-eluting stents: lesson from restenosis cases.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20051001
Title: Sirolimus-eluting stent implantation in diabetic patients with multivessel coronary artery disease.
Journal: American heart journal 20051001
Title: Pirfenidone inhibits obliterative airway disease in mouse tracheal allografts.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20051001
Title: The Candida albicans vacuole is required for differentiation and efficient macrophage killing.
Journal: Eukaryotic cell 20051001
Title: Inhibition of the mammalian target of rapamycin and the induction of cell cycle arrest in mantle cell lymphoma cells.
Journal: Haematologica 20051001
Title: Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate-1/phosphatidylinositol 3-kinase cascade.
Journal: Molecular cancer therapeutics 20051001
Title: Disruption of parallel and converging signaling pathways contributes to the synergistic antitumor effects of simultaneous mTOR and EGFR inhibition in GBM cells.
Journal: Neoplasia (New York, N.Y.) 20051001
Title: [Experimental study on the effects of rapamycin in prevention of rat corneal allograft rejection].
Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20051001
Title: Potential role of mammalian target of rapamycin inhibitors in breast cancer therapy.
Journal: Clinical breast cancer 20051001
Title: [Primary study of vasculogenic mimicry induced by hypoxia in epithelial ovarian carcinoma].
Journal: Zhonghua fu chan ke za zhi 20051001
Title: [Drug-eluting stents: indications, limits and future development].
Journal: Archives des maladies du coeur et des vaisseaux 20051001
Title: Sirolimus inhibits platelet-derived growth factor-induced collagen synthesis in rat vascular smooth muscle cells.
Journal: Transplantation proceedings 20051001
Title: A pilot study of immunosuppression minimization after pancreas-kidney transplantation utilizing thymoglobulin induction and sirolimus maintenance therapy.
Journal: Transplantation proceedings 20051001
Title: Experience with sirolimus for calcineurin minimization/elimination in pancreas-after-kidney transplantation.
Journal: Transplantation proceedings 20051001
Title: Metabolic effect of sirolimus versus mycophenolate mofetil on pancreatic graft function in the early posttransplant period.
Journal: Transplantation proceedings 20051001
Title: Diabetes and percutaneous coronary intervention in the setting of an acute coronary syndrome.
Journal: Diabetes & vascular disease research 20051001
Title: [Sirolimus for rescue of recurrent acute rejection and diabetes mellitus after liver transplantation: report of one case].
Journal: Revista medica de Chile 20051001
Title: Sirolimus: a new immunosuppressant.
Journal: The Journal of the Association of Physicians of India 20051001
Title: [Advances on PI3K/Akt/mTOR signalling pathway in malignancies].
Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology 20051001
Title: Rapamycin, but not FK-506, increases endothelial tissue factor expression: implications for drug-eluting stent design.
Journal: Circulation 20050927
Title: Low incidence of malignancy among sirolimus/cyclosporine-treated renal transplant recipients.
Journal: Transplantation 20050927
Title: Comparison of steroid avoidance in tacrolimus/mycophenolate mofetil and tacrolimus/sirolimus combination in kidney transplantation monitored by surveillance biopsy.
Journal: Transplantation 20050927
Title: mTOR inhibition and its effect on cancer in transplantation.
Journal: Transplantation 20050927
Title: Lithium induces autophagy by inhibiting inositol monophosphatase.
Journal: The Journal of cell biology 20050926
Title: Shp2 is required for protein kinase C-dependent phosphorylation of serine 307 in insulin receptor substrate-1.
Journal: The Journal of biological chemistry 20050923
Title: The FK506 binding protein Fpr3 counteracts protein phosphatase 1 to maintain meiotic recombination checkpoint activity.
Journal: Cell 20050923
Title: Late incomplete stent apposition after sirolimus-eluting stent implantation: a serial intravascular ultrasound analysis.
Journal: Journal of the American College of Cardiology 20050920
Title: Overexpression of NBS1 contributes to transformation through the activation of phosphatidylinositol 3-kinase/Akt.
Journal: The Journal of biological chemistry 20050916
Title: Tolerability of cyclosphosphamide and methotrexate induction immunosuppression in nonhuman primates.
Journal: Toxicology 20050915
Title: Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
Journal: Bioorganic & medicinal chemistry letters 20050915
Title: Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy.
Journal: Cancer research 20050915
Title: Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis.
Journal: Genes & development 20050915
Title: Late restenosis in patients receiving a polymer-coated sirolimus-eluting stent.
Journal: Annals of internal medicine 20050906
Title: Effectiveness of sirolimus-eluting stent implantation for the treatment of ostial left anterior descending artery stenosis with intravascular ultrasound guidance.
Journal: Journal of the American College of Cardiology 20050906
Title: Local perivascular delivery of anti-restenotic agents from a drug-eluting poly(epsilon-caprolactone) stent cuff.
Journal: Biomaterials 20050901
Title: One year clinical follow up of paclitaxel eluting stents for acute myocardial infarction compared with sirolimus eluting stents.
Journal: Heart (British Cardiac Society) 20050901
Title: A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein {beta} and NF-{kappa}B activity in Hodgkin and anaplastic large cell lymphomas.
Journal: Blood 20050901
Title: CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium.
Journal: Cancer 20050901
Title: Cardiovascular risk profile with the new immunosuppressive combinations after renal transplantation.
Journal: Journal of hypertension 20050901
Title: Sirolimus in combination with tacrolimus is associated with worse renal allograft survival compared to mycophenolate mofetil combined with tacrolimus.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901
Title: Proteinuria developing after clinical islet transplantation resolves with sirolimus withdrawal and increased tacrolimus dosing.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901
Title: Analysis of exposure-response relationship in everolimus-cyclosporine combination regimen.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901
Title: Therapeutic drug monitoring for everolimus in heart transplant recipients: flawed model or a model for future use?
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901
Title: Bone metabolism in renal transplant patients treated with cyclosporine or sirolimus.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050901
Title: Immune cells in a heterotopic lamb-to-pig bronchial xenograft model.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050901
Title: Recurrence of in-stent restenosis in cardiac allograft vasculopathy following implantation of a sirolimus-eluting stent.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050901
Title: lipase-catalyzed regioselective esterification of rapamycin: synthesis of temsirolimus (CCI-779).
Journal: Organic letters 20050901
Title: Simultaneous measurement of sirolimus and everolimus in whole blood by HPLC with ultraviolet detection.
Journal: Clinical chemistry 20050901
Title: Effectiveness of the concomitant use of bivalirudin and drug-eluting stents (from the prospective, multicenter BivAlirudin and Drug-Eluting STents [ADEST] study).
Journal: The American journal of cardiology 20050901
Title: Inhibition of PI-3 kinase/Akt/mTOR, but not calcineurin signaling, reverses insulin-like growth factor I-induced protection against glucose toxicity in cardiomyocyte contractile function.
Journal: The Journal of endocrinology 20050901
Title: Re-stenosis of a sirolimus-coated stent in a heart transplant recipient with allograft vasculopathy.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050901
Title: Sirolimus- and taxol-eluting stents differ towards intimal hyperplasia and re-endothelialization.
Journal: The Journal of invasive cardiology 20050901
Title: Genetic analysis of the TOR pathway in Aspergillus nidulans.
Journal: Eukaryotic cell 20050901
Title: Incremental cost-effectiveness of drug-eluting stents compared with a third-generation bare-metal stent in a real-world setting: randomised Basel Stent Kosten Effektivitäts Trial (BASKET).
Journal: Lancet (London, England) 20050901
Title: An evaluation of the Abbott IMx sirolimus assay in relation to a high-performance liquid chromatography-ultraviolet method.
Journal: Annals of clinical biochemistry 20050901
Title: Incidence and predictors of restenosis after sirolimus-eluting stent implantation in high-risk patients.
Journal: American heart journal 20050901
Title: Update on drug-eluting coronary stents.
Journal: Expert review of cardiovascular therapy 20050901
Title: How soon can a patient undergo noncardiac surgery after receiving a drug-eluting stent?
Journal: Cleveland Clinic journal of medicine 20050901
Title: [Molecular targeted therapy for malignant brain tumors].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050901
Title: Percutaneous treatment of the left main coronary artery ostial obstruction following aortic valve replacement.
Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20050901
Title: Sirolimus as primary immunosuppression agent in kidney transplant recipients: Akdeniz University experience.
Journal: Transplantation proceedings 20050901
Title: Early acute rejection episodes in renal transplantation in relation to immunosuppression protocols: an audit of 100 cases.
Journal: Transplantation proceedings 20050901
Title: Observations on quadruple immunosuppression maintenance therapy using rapamycin, low-dose cyclosporine, mycophenolate mofetil, and prednisone following ATG induction.
Journal: Transplantation proceedings 20050901
Title: [Sirolimus-eluting stent for in-stent restenosis treatment: single center results in an unselected study population].
Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20050901
Title: Active stents in diabetic patients.
Journal: Diabetes & metabolism 20050901
Title: Pharmacokinetics of sirolimus in Thai healthy volunteers.
Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20050901
Title: Kaposi's sarcoma after renal transplantation.
Journal: The New England journal of medicine 20050825
Title: Kaposi's sarcoma after renal transplantation.
Journal: The New England journal of medicine 20050825
Title: Images in cardiovascular medicine. Giant coronary aneurysm formation after sirolimus-eluting stent implantation in Kawasaki disease.
Journal: Circulation 20050823
Title: Enhanced radiation damage of tumor vasculature by mTOR inhibitors.
Journal: Oncogene 20050818
Title: Sirolimus-eluting and paclitaxel-eluting stents for coronary revascularization.
Journal: The New England journal of medicine 20050818
Title: Paclitaxel-eluting or sirolimus-eluting stents to prevent restenosis in diabetic patients.
Journal: The New England journal of medicine 20050818
Title: Healing Achilles--sirolimus versus paclitaxel.
Journal: The New England journal of medicine 20050818
Title: Sirolimus-eluting stents vs paclitaxel-eluting stents in patients with coronary artery disease: meta-analysis of randomized trials.
Journal: JAMA 20050817
Title: [Short and long-term therapeutic effects of rapamycin-eluting stent and paclitaxel-eluting stent in treatment of coronary disease with complicated lesions].
Journal: Zhonghua yi xue za zhi 20050817
Title: Bifurcation coronary lesions treated with the 'crush' technique: an intravascular ultrasound analysis.
Journal: Journal of the American College of Cardiology 20050816
Title: Clinical and angiographic outcome after implantation of drug-eluting stents in bifurcation lesions with the crush stent technique: importance of final kissing balloon post-dilation.
Journal: Journal of the American College of Cardiology 20050816
Title: Rapamycin stimulates apoptosis of childhood acute lymphoblastic leukemia cells.
Journal: Blood 20050815
Title: A prospective, randomized trial of tacrolimus in combination with sirolimus or mycophenolate mofetil in kidney transplantation: results at 1 year.
Journal: Transplantation 20050815
Title: Robust tolerance to fully allogeneic islet transplants achieved by chimerism with minimal conditioning.
Journal: Transplantation 20050815
Title: Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.
Journal: Cancer research 20050815
Title: Novel fusion protein approach for efficient high-throughput screening of small molecule-mediating protein-protein interactions in cells and living animals.
Journal: Cancer research 20050815
Title: [Treatment and prevention of restenosis after percutaneous coronary intervention. Balloons, stents, radioactive rays and drug-releasing stents].
Journal: Ugeskrift for laeger 20050815
Title: Phase II study of temsirolimus (CCI-779), a novel inhibitor of mTOR, in heavily pretreated patients with locally advanced or metastatic breast cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050810
Title: Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050810
Title: Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050810
Title: 4E-binding protein phosphorylation and eukaryotic initiation factor-4E release are required for airway smooth muscle hypertrophy.
Journal: American journal of respiratory cell and molecular biology 20050801
Title: Resolution of renal allograft-associated post-transplant lymphoproliferative disorder with the introduction of sirolimus.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050801
Title: Late thrombosis of sirolimus-eluting stents following noncardiac surgery.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050801
Title: Everolimus treatment downregulates renocortical cyclooxygenase-2 expression in the rat kidney.
Journal: British journal of pharmacology 20050801
Title: Selective versus exclusive use of sirolimus-eluting stent implantation in multivessel coronary artery disease.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050801
Title: Late thrombosis following treatment of in-stent restenosis with drug-eluting stents after discontinuation of antiplatelet therapy.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050801
Title: Prevention of restenosis by a novel drug-eluting stent system with a dose-adjustable, polymer-free, on-site stent coating.
Journal: European heart journal 20050801
Title: Impact of sirolimus-eluting stents on outcomes of patients treated for acute myocardial infarction by primary angioplasty.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050801
Title: Pre-transplant IFN-gamma ELISPOTs are associated with post-transplant renal function in African American renal transplant recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050801
Title: Adding sirolimus to tacrolimus-based immunosuppression in pediatric renal transplant recipients reduces tacrolimus exposure.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050801
Title: Islet transplantation in type 1 diabetes mellitus using cultured islets and steroid-free immunosuppression: Miami experience.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050801
Title: Use of drug-eluting stents for the treatment of in-stent restenosis in routine clinical practice.
Journal: Coronary artery disease 20050801
Title: An expanding role for mTOR in cancer.
Journal: Trends in molecular medicine 20050801
Title: Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme.
Journal: Investigational new drugs 20050801
Title: Gas6 induces Akt/mTOR-mediated mesangial hypertrophy in diabetic nephropathy.
Journal: Kidney international 20050801
Title: Mycophenolate mofetil in islet cell transplant: variable pharmacokinetics but good correlation between total and unbound concentrations.
Journal: Journal of clinical pharmacology 20050801
Title: A phase I multiple-dose escalation study characterizing pharmacokinetics and safety of ABT-578 in healthy subjects.
Journal: Journal of clinical pharmacology 20050801
Title: Generalized, pruritic, ulcerating maculopapular rash necessitating cessation of sirolimus in a liver transplantation patient.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20050801
Title: Sirolimus-related toxicity in stem cell transplantation.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050801
Title: Sirolimus in combination with tacrolimus and corticosteroids for the treatment of resistant chronic graft-versus-host disease.
Journal: British journal of haematology 20050801
Title: Sirolimus in pediatric solid organ transplantation.
Journal: Pediatric transplantation 20050801
Title: Sirolimus in pediatric patients: results in the first 6 months post-renal transplant.
Journal: Pediatric transplantation 20050801
Title: Cardiac tamponade in a pediatric renal transplant recipient on sirolimus therapy.
Journal: Pediatric transplantation 20050801
Title: Comparison of short- (one month) and long- (twelve months) term outcomes of sirolimus- versus paclitaxel-eluting stents in 293 consecutive patients with diabetes mellitus (from the RESEARCH and T-SEARCH registries).
Journal: The American journal of cardiology 20050801
Title: RAD001 (everolimus) improves the efficacy of replicating adenoviruses that target colon cancer.
Journal: Cancer research 20050801
Title: Sirolimus-eluting stents for treatment of complex bypass graft disease: insights from the SECURE registry.
Journal: The Journal of invasive cardiology 20050801
Title: Prospective native coronary artery stenosis treated with sirolimus-eluting stent (ONASSIS) registry--acute results and mid-term outcomes: a single-center experience.
Journal: The Journal of invasive cardiology 20050801
Title: One-year clinical outcome after coronary stenting of very small vessels using 2.25 mm sirolimus- and paclitaxel-eluting stents: a comparison between the RESEARCH and T-SEARCH registries.
Journal: The Journal of invasive cardiology 20050801
Title: Balloon alignment T-stenting for bifurcation coronary artery disease using the sirolimus-eluting stent.
Journal: The Journal of invasive cardiology 20050801
Title: Sirolimus-eluting stent implantation and beta-irradiation for the treatment of in-stent restenotic lesions: comparison of underlying mechanisms of acute gain and late loss as assessed by volumetric intravascular ultrasound.
Journal: American heart journal 20050801
Title: [Drug eluting stents: from evidence based medicine to clinical practice].
Journal: Annales de cardiologie et d'angeiologie 20050801
Title: Pim family kinases enhance tumor growth of prostate cancer cells.
Journal: Molecular cancer research : MCR 20050801
Title: Successful use of the new immune-suppressor sirolimus in IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome).
Journal: The Journal of pediatrics 20050801
Title: A high-throughput method for screening of rapamycin-producing strains of Streptomyces hygroscopicus by cultivation in 96-well microtiter plates.
Journal: Biotechnology letters 20050801
Title: [Improved outcome with sirolimus-cyclosporine regimen in high-risk renal transplant recipients].
Journal: Orvosi hetilap 20050731
Title: Everolimus versus mycophenolate mofetil in the prevention of rejection in de novo renal transplant recipients: a 3-year randomized, multicenter, phase III study.
Journal: Transplantation 20050727
Title: Sirolimus may not cause neurotoxicity in kidney and liver transplant recipients.
Journal: Neurology 20050726
Title: Mutasynthesis of rapamycin analogues through the manipulation of a gene governing starter unit biosynthesis.
Journal: Angewandte Chemie (International ed. in English) 20050725
Title: Methionine sulfoximine treatment and carbon starvation elicit Snf1-independent phosphorylation of the transcription activator Gln3 in Saccharomyces cerevisiae.
Journal: The Journal of biological chemistry 20050722
Title: Antiproliferative profile of sirolimus and mycophenolate mofetil: impact of the SI/MPL ratio.
Journal: International journal of cardiology 20050720
Title: Sirolimus-eluting stents associated with paradoxic coronary vasoconstriction.
Journal: Journal of the American College of Cardiology 20050719
Title: Endothelial dysfunction after sirolimus-eluting stent placement.
Journal: Journal of the American College of Cardiology 20050719
Title: Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase.
Journal: The Journal of biological chemistry 20050715
Title: Body weight alterations under early corticosteroid withdrawal and chronic corticosteroid therapy with modern immunosuppression.
Journal: Transplantation 20050715
Title: Differential effect of calcineurin inhibitors, anti-CD25 antibodies and rapamycin on the induction of FOXP3 in human T cells.
Journal: Transplantation 20050715
Title: Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050715
Title: Regulation of the phosphorylation and integrity of protein synthesis initiation factor eIF4GI and the translational repressor 4E-BP1 by p53.
Journal: Oncogene 20050714
Title: Differential response of delayed healing and persistent inflammation at sites of overlapping sirolimus- or paclitaxel-eluting stents.
Journal: Circulation 20050712
Title: Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase.
Journal: The Journal of biological chemistry 20050708
Title: Amino acid signaling through the mammalian target of rapamycin (mTOR) pathway: Role of glutamine and of cell shrinkage.
Journal: Journal of cellular physiology 20050701
Title: Drug-eluting stents compared with thin-strut bare stents for the reduction of restenosis: a prospective, randomized trial.
Journal: European heart journal 20050701
Title: Shiga toxins activate translational regulation pathways in intestinal epithelial cells.
Journal: Cellular signalling 20050701
Title: Effects of sirolimus on mesangial cell cholesterol homeostasis: a novel mechanism for its action against lipid-mediated injury in renal allografts.
Journal: American journal of physiology. Renal physiology 20050701
Title: Follicle-stimulating hormone activates p70 ribosomal protein S6 kinase by protein kinase A-mediated dephosphorylation of Thr 421/Ser 424 in primary Sertoli cells.
Journal: Molecular endocrinology (Baltimore, Md.) 20050701
Title: A novel class of dual-family immunophilins.
Journal: The Journal of biological chemistry 20050701
Title: Rapamycin ameliorates proteinuria-associated tubulointerstitial inflammation and fibrosis in experimental membranous nephropathy.
Journal: Journal of the American Society of Nephrology : JASN 20050701
Title: Modulation of insulin action by dietary proteins and amino acids: role of the mammalian target of rapamycin nutrient sensing pathway.
Journal: Current opinion in clinical nutrition and metabolic care 20050701
Title: Calcineurin inhibitor withdrawal from sirolimus-based therapy in kidney transplantation: a systematic review of randomized trials.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050701
Title: Rapamycin: a new string to the antiproteinuric bow?
Journal: Journal of the American Society of Nephrology : JASN 20050701
Title: Glycogen autophagy in the liver and heart of newborn rats. The effects of glucagon, adrenalin or rapamycin.
Journal: Histology and histopathology 20050701
Title: Phosphotidylinositol-3 kinase-mediated signals in mice immunized with the 57 kDa major antigenic outer-membrane protein of Shigella dysenteriae type 1.
Journal: Journal of medical microbiology 20050701
Title: Influence of everolimus on steady-state pharmacokinetics of cyclosporine in maintenance renal transplant patients.
Journal: Journal of clinical pharmacology 20050701
Title: Rapamycin and FK506 reduce skeletal muscle voltage sensor expression and function.
Journal: Cell calcium 20050701
Title: Roles of deletion and regulation in creating mixed chimerism and allograft tolerance using a nonlymphoablative irradiation-free protocol.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050701
Title: Stent-based delivered anti-proliferative drugs in the prevention of coronary stent restenosis.
Journal: Current medicinal chemistry. Cardiovascular and hematological agents 20050701
Title: Sirolimus and thrombotic microangiopathy after allogeneic hematopoietic stem cell transplantation.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050701
Title: The TOR and EGO protein complexes orchestrate microautophagy in yeast.
Journal: Molecular cell 20050701
Title: The efficacy of sirolimus-eluting stents versus bare metal stents for diabetic patients undergoing elective percutaneous coronary intervention.
Journal: The Journal of invasive cardiology 20050701
Title: Evolving use of drug-eluting stents in diabetic patients.
Journal: The Journal of invasive cardiology 20050701
Title: Higher exposure to mycophenolic acid with sirolimus than with cyclosporine cotreatment.
Journal: Clinical pharmacology and therapeutics 20050701
Title: [Drug-eluting stents and other anti-restenosis devices].
Journal: Revista espanola de cardiologia 20050701
Title: Cilomilast, tacrolimus and rapamycin modulate dendritic cell function in the elicitation phase of allergic contact dermatitis.
Journal: The British journal of dermatology 20050701
Title: Control of advanced and refractory acute myelogenous leukaemia with sirolimus-based non-myeloablative allogeneic stem cell transplantation.
Journal: British journal of haematology 20050701
Title: Moving beyond the cost per quality-adjusted life year: modelling the budgetary impact and clinical outcomes associated with the use of sirolimus-eluting stents.
Journal: The Canadian journal of cardiology 20050701
Title: Modulation of tissue factor expression by rapamycin and FK-506 in lipopolysaccharide-stimulated human mononuclear cells and serum-stimulated aortic smooth muscle cells.
Journal: Thrombosis and haemostasis 20050701
Title: Angiotensin IV enhances phosphorylation of 4EBP1 by multiple signaling events in lung endothelial cells.
Journal: Molecular and cellular biochemistry 20050701
Title: Late angiographic stent thrombosis (LAST) events with drug-eluting stents.
Journal: Journal of the American College of Cardiology 20050621
Title: Synergistic growth inhibition by Iressa and Rapamycin is modulated by VHL mutations in renal cell carcinoma.
Journal: British journal of cancer 20050620
Title: Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells.
Journal: Blood 20050615
Title: Activation of protein synthesis in cardiomyocytes by the hypertrophic agent phenylephrine requires the activation of ERK and involves phosphorylation of tuberous sclerosis complex 2 (TSC2).
Journal: The Biochemical journal 20050615
Title: TCR engagement increases hypoxia-inducible factor-1 alpha protein synthesis via rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050615
Title: Recombinant p21 protein inhibits lymphocyte proliferation and transcription factors.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050615
Title: Comparison of effectiveness of sirolimus-eluting stents versus bare metal stents for percutaneous coronary intervention in patients at high risk for coronary restenosis or clinical adverse events.
Journal: The American journal of cardiology 20050615
Title: Risk of thrombosis with the use of sirolimus-eluting stents for percutaneous coronary intervention (from registry and clinical trial data).
Journal: The American journal of cardiology 20050615
Title: Antitumor activity of rapamycin in a transgenic mouse model of ErbB2-dependent human breast cancer.
Journal: Cancer research 20050615
Title: A crevice adjoining the ribosome tunnel: hints for cotranslational folding.
Journal: FEBS letters 20050613
Title: Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1alpha.
Journal: The Journal of biological chemistry 20050610
Title: Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells.
Journal: The Journal of biological chemistry 20050603
Title: Rapamycin induces tumor-specific thrombosis via tissue factor in the presence of VEGF.
Journal: Blood 20050601
Title: Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival.
Journal: Blood 20050601
Title: Rapamycin inhibits fibronectin-induced migration of the human arterial smooth muscle line (E47) through the mammalian target of rapamycin.
Journal: American journal of physiology. Heart and circulatory physiology 20050601
Title: Estimation of pharmacokinetic parameters from non-compartmental variables using Microsoft Excel.
Journal: Computers in biology and medicine 20050601
Title: Long-term treatment of bile duct-ligated rats with rapamycin (sirolimus) significantly attenuates liver fibrosis: analysis of the underlying mechanisms.
Journal: The Journal of pharmacology and experimental therapeutics 20050601
Title: Identification of mTOR as a novel bifunctional target in chronic myeloid leukemia: dissection of growth-inhibitory and VEGF-suppressive effects of rapamycin in leukemic cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050601
Title: Mycotic aneurysm of left anterior descending artery after sirolimus-eluting stent implantation: a case report.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050601
Title: Immediate and mid-term outcomes of sirolimus-eluting stent implantation for chronic total occlusions.
Journal: European heart journal 20050601
Title: Drug-eluting stents for chronic total occlusions make sense, but it is too early to close the discussion.
Journal: European heart journal 20050601
Title: Effect of the immunosuppressive regime of Edmonton protocol on the long-term in vitro insulin secretion from islets of two different species and age categories.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20050601
Title: The FK506-binding protein of the malaria parasite, Plasmodium falciparum, is a FK506-sensitive chaperone with FK506-independent calcineurin-inhibitory activity.
Journal: Molecular and biochemical parasitology 20050601
Title: Activation of CREB by tauroursodeoxycholic acid protects cholangiocytes from apoptosis induced by mTOR inhibition.
Journal: Hepatology (Baltimore, Md.) 20050601
Title: Early cyclosporine a withdrawal in kidney-transplant recipients receiving sirolimus prevents progression of chronic pathologic allograft lesions.
Journal: The Journal of urology 20050601
Title: Clinical outcomes after sirolimus-eluting stent implantation for de novo saphenous vein graft lesions.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050601
Title: Rapamycin inhibits human renal epithelial cell proliferation: effect on cyclin D3 mRNA expression and stability.
Journal: Kidney international 20050601
Title: BOOP is common in cardiac transplant recipients switched from a calcineurin inhibitor to sirolimus.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050601
Title: Everolimus alters the bronchoalveolar lavage and endobronchial biopsy immunologic profile post-human lung transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050601
Title: A prospective randomized trial of steroid-free maintenance regimens in kidney transplant recipients--an interim analysis.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050601
Title: Very late thrombosis after implantation of sirolimus eluting stent.
Journal: Heart (British Cardiac Society) 20050601
Title: Fatal infection after rapamycin eluting coronary stent implantation.
Journal: Heart (British Cardiac Society) 20050601
Title: A paclitaxel coated stent used for in-stent restenosis within a sirolimus coated stent fails to protect against recurrent restenosis.
Journal: Heart (British Cardiac Society) 20050601
Title: Differential regulation of smooth muscle markers in human bone marrow-derived mesenchymal stem cells.
Journal: Journal of hypertension 20050601
Title: Who let the bugs in?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050601
Title: Underexpansion of sirolimus-eluting stents: incidence and relationship to delivery pressure.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050601
Title: Stent-based delivery of ABT-578 via a phosphorylcholine surface coating reduces neointimal formation in the porcine coronary model.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050601
Title: Incidence and predictors of target vessel revascularization and clinical event rates of the sirolimus-eluting coronary stent (results from the prospective multicenter German Cypher Stent Registry).
Journal: The American journal of cardiology 20050601
Title: CEDIA sirolimus assay compared with HPLC-MS/MS and HPLC-UV in transplant recipient specimens.
Journal: Therapeutic drug monitoring 20050601
Title: An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways.
Journal: Nature methods 20050601
Title: Sirolimus for solid organ transplantation in children.
Journal: Pediatric transplantation 20050601
Title: Replacing calcineurin inhibitors with mTOR inhibitors in children.
Journal: Pediatric transplantation 20050601
Title: Rapamycin inhibits human in stent restenosis vascular smooth muscle cells independently of pRB phosphorylation and p53.
Journal: Cardiovascular research 20050601
Title: Sirolimus-eluting stent for in-stent restenosis of left main coronary artery in takayasu arteritis.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20050601
Title: Adverse effects of local or systemic application of rapamycin for the prevention of neointimal hyperplasia.
Journal: The Annals of thoracic surgery 20050601
Title: Drug eluting stents in 2005.
Journal: Heart (British Cardiac Society) 20050601
Title: The efficacy of sirolimus in the treatment of patients with refractory uveitis.
Journal: The British journal of ophthalmology 20050601
Title: Angiographic and clinical outcome for the treatment of in-stent restenosis with sirolimus-eluting stent compared to vascular brachytherapy.
Journal: Zeitschrift fur Kardiologie 20050601
Title: Short-term rapamycin for inhibition of neointima formation after balloon-mediated aortic injury in rats: is there a window of opportunity for systemic prophylaxis of restenosis?
Journal: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20050601
Title: Farnesyltransferase inhibitors reverse altered growth and distribution of actin filaments in Tsc-deficient cells via inhibition of both rapamycin-sensitive and -insensitive pathways.
Journal: Molecular cancer therapeutics 20050601
Title: Drug coated stents for carotid intervention.
Journal: The Journal of cardiovascular surgery 20050601
Title: Delayed renal graft function: the influence of immunosuppression.
Journal: Transplantation proceedings 20050601
Title: Toward the definition of immunosuppressive regimens with antitumor activity.
Journal: Transplantation proceedings 20050601
Title: Successful use of sirolimus in a patient with bulky ovarian metastasis of hepatocellular carcinoma after liver transplantation.
Journal: Transplantation proceedings 20050601
Title: De novo immunosuppression with sirolimus and tacrolimus in heart transplant recipients compared with cyclosporine and mycophenolate mofetil: a one-year follow-up analysis.
Journal: Transplantation proceedings 20050601
Title: Cyclosporine and sirolimus interaction in a kidney transplant patient.
Journal: Transplantation proceedings 20050601
Title: [Advances in adjunctive pharmacological therapy for percutaneous coronary interventions].
Journal: Revista espanola de cardiologia 20050601
Title: Placement of a sirolimus-coated stent in the distal left internal mammary artery of an 8-year-old boy.
Journal: The Journal of invasive cardiology 20050601
Title: The present and future of drug-eluting stents.
Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20050601
Title: Restenosis treatment in the drug-eluting stent era.
Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20050601
Title: Rapamycin pre-treatment preserves viability, ATP level and catabolic capacity during carbon starvation of Saccharomyces cerevisiae.
Journal: Yeast (Chichester, England) 20050601
Title: [Experimental study of Mytrolimus-eluting stents on preventing restenosis in porcine coronary model].
Journal: Zhonghua xin xue guan bing za zhi 20050601
Title: Drug eluting stents in acute myocardial infarction.
Journal: Panminerva medica 20050601
Title: The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability.
Journal: The Journal of biological chemistry 20050527
Title: Target of rapamycin-dependent activation of S6 kinase is a central step in the transduction of nutritional signals during egg development in a mosquito.
Journal: The Journal of biological chemistry 20050527
Title: The rapamycin analog CCI-779 is a potent inhibitor of pancreatic cancer cell proliferation.
Journal: Biochemical and biophysical research communications 20050527
Title: Response to 'Exceptional circumstances and heart transplantation' letter.
Journal: The New Zealand medical journal 20050520
Title: Withdrawal of immunosuppression contributing to the remission of malignant melanoma: a case report.
Journal: Cancer immunity 20050519
Title: Multiple overlapping drug-eluting stents to treat diffuse disease of the left anterior descending coronary artery.
Journal: Journal of the American College of Cardiology 20050517
Title: Cyclosporin A and tacrolimus, but not rapamycin, inhibit MHC-restricted antigen presentation pathways in dendritic cells.
Journal: Blood 20050515
Title: Ryanodine receptor subtype 2 encodes Ca2+ oscillations activated by acetylcholine via the M2 muscarinic receptor/cADP-ribose signalling pathway in duodenum myocytes.
Journal: Journal of cell science 20050515
Title: Comparison of thrombosis and restenosis risk from stent length of sirolimus-eluting stents versus bare metal stents.
Journal: The American journal of cardiology 20050515
Title: Drug-eluting stents versus bare metal stents in percutaneous coronary interventions (a meta-analysis).
Journal: The American journal of cardiology 20050515
Title: Comparison of C-reactive protein levels before and after coronary stenting and restenosis among patients treated with sirolimus-eluting versus bare metal stents.
Journal: The American journal of cardiology 20050515
Title: Intravascular ultrasound stent area of sirolimus-eluting stents and its impact on late outcome.
Journal: The American journal of cardiology 20050515
Title: Reduction in calcineurin inhibitor exposure and maintenance of effective immunosuppression: clinical experience with everolimus (Certican).
Journal: Transplantation 20050515
Title: Introducing everolimus (Certican) in organ transplantation: an overview of preclinical and early clinical developments.
Journal: Transplantation 20050515
Title: Concentration-controlled everolimus (Certican): combination with reduced dose calcineurin inhibitors.
Journal: Transplantation 20050515
Title: Clinical experience with everolimus (Certican): optimizing dose and tolerability.
Journal: Transplantation 20050515
Title: Clinical experience with everolimus (Certican) in elderly recipients: the 'old-for-old' concept.
Journal: Transplantation 20050515
Title: Clinical experience with everolimus (Certican) in young renal transplant recipients.
Journal: Transplantation 20050515
Title: Clinical experience with everolimus (Certican): a summary.
Journal: Transplantation 20050515
Title: Sourcing a chemical succession for cyclosporin from parasites and human pathogens.
Journal: Drug discovery today 20050515
Title: The efficacy of sirolimus- and paclitaxel-eluting stents: a meta-analysis of randomized controlled trials.
Journal: The Canadian journal of cardiology 20050515
Title: Four-year angiographic and intravascular ultrasound follow-up of patients treated with sirolimus-eluting stents.
Journal: Circulation 20050510
Title: Insulin stimulates postsynaptic density-95 protein translation via the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway.
Journal: The Journal of biological chemistry 20050506
Title: Rapamycin induces apoptosis of JN-DSRCT-1 cells by increasing the Bax : Bcl-xL ratio through concurrent mechanisms dependent and independent of its mTOR inhibitory activity.
Journal: Oncogene 20050505
Title: Tirofiban and sirolimus-eluting stent vs abciximab and bare-metal stent for acute myocardial infarction: a randomized trial.
Journal: JAMA 20050504
Title: Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents.
Journal: JAMA 20050504
Title: Drug-eluting stents in acute myocardial infarction: is science catching up with practice?
Journal: JAMA 20050504
Title: Catalase induced expression of inflammatory mediators via activation of NF-kappaB, PI3K/AKT, p70S6K, and JNKs in BV2 microglia.
Journal: Cellular signalling 20050501
Title: Trans-10,cis-12 CLA increases adipocyte lipolysis and alters lipid droplet-associated proteins: role of mTOR and ERK signaling.
Journal: Journal of lipid research 20050501
Title: Sirolimus rescue of renal failure in children after combined liver-kidney transplantation.
Journal: Pediatric nephrology (Berlin, Germany) 20050501
Title: Combination therapy with sirolimus (rapamycin) and tacrolimus (FK-506) in treatment of refractory minimal change nephropathy, a clinical case report.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050501
Title: Effect of a fermented ginseng extract, BST204, on the expression of cyclooxygenase-2 in murine macrophages.
Journal: International immunopharmacology 20050501
Title: Role of mammalian target of rapamycin signaling in compensatory renal hypertrophy.
Journal: Journal of the American Society of Nephrology : JASN 20050501
Title: Simultaneous kissing drug-eluting stent technique for percutaneous treatment of bifurcation lesions in large-size vessels.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050501
Title: Warfarin or low-molecular-weight heparin therapy does not prolong pig-to-primate cardiac xenograft function.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050501
Title: IDEC-131 (anti-CD154), sirolimus and donor-specific transfusion facilitate operational tolerance in non-human primates.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050501
Title: Rapamycin successfully treats post-transplant autoimmune hepatitis.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050501
Title: Preservation of renal structure and function at 2 years without calcineurin inhibitor use.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050501
Title: Effect of different immunosuppressive therapies on the lipid pattern in kidney-transplanted rats.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050501
Title: Inter-laboratory differences in sirolimus results from six sirolimus testing centers using HPLC tandem mass spectrometry (LC/MS/MS).
Journal: Clinica chimica acta; international journal of clinical chemistry 20050501
Title: Blood concentrations of everolimus are markedly increased by ketoconazole.
Journal: Journal of clinical pharmacology 20050501
Title: IL-2 increases human telomerase reverse transcriptase activity transcriptionally and posttranslationally through phosphatidylinositol 3'-kinase/Akt, heat shock protein 90, and mammalian target of rapamycin in transformed NK cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050501
Title: Inhibition of mammalian target of rapamycin potentiates thrombin-induced intercellular adhesion molecule-1 expression by accelerating and stabilizing NF-kappa B activation in endothelial cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050501
Title: Insulin and IGF-I stimulate the formation of the eukaryotic initiation factor 4F complex and protein synthesis in C2C12 myotubes independent of availability of external amino acids.
Journal: The Journal of endocrinology 20050501
Title: PWT-458, a novel pegylated-17-hydroxywortmannin, inhibits phosphatidylinositol 3-kinase signaling and suppresses growth of solid tumors.
Journal: Cancer biology & therapy 20050501
Title: Mucositis after allogeneic hematopoietic stem cell transplantation: a cohort study of methotrexate- and non-methotrexate-containing graft-versus-host disease prophylaxis regimens.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050501
Title: A fast and simple high-performance liquid chromatography/mass spectrometry method for simultaneous measurement of whole blood tacrolimus and sirolimus.
Journal: Archives of pathology & laboratory medicine 20050501
Title: Use of a sirolimus-eluting stent to treat failure of a nonpolymer release paclitaxel-eluting stent implanted for in-stent restenosis.
Journal: The Journal of invasive cardiology 20050501
Title: Replicating oncolytic virus therapeutics - Third International Meeting.
Journal: IDrugs : the investigational drugs journal 20050501
Title: Sirolimus does double duty after organ transplantation.
Journal: The Lancet. Oncology 20050501
Title: Clinical and cost-effectiveness of newer immunosuppressive regimens in renal transplantation: a systematic review and modelling study.
Journal: Health technology assessment (Winchester, England) 20050501
Title: Effects of calcineurin inhibitors on sirolimus pharmacokinetics during staggered administration in renal transplant recipients.
Journal: Pharmacotherapy 20050501
Title: Inhibiting phosphoinositide 3-kinases.
Journal: Cancer biology & therapy 20050501
Title: Preservation of renal function after heart transplantation: initial single-center experience with sirolimus.
Journal: Transplantation proceedings 20050501
Title: Lipid metabolism in renal transplant patients receiving tacrolimus/sirolimus combination therapy.
Journal: Transplantation proceedings 20050501
Title: Effects of rapamycin on the arterial inflammatory response in atherosclerotic plaques in Apo-E knockout mice.
Journal: Transplantation proceedings 20050501
Title: Successful conversion to rapamycin for calcineurin inhibitor-related neurotoxicity following liver transplantation.
Journal: Transplantation proceedings 20050501
Title: Gonadal function and immunosuppressive therapy after renal transplantation.
Journal: Transplantation proceedings 20050501
Title: Severe hearing loss after liver transplantation.
Journal: Transplantation proceedings 20050501
Title: [Impact of coronary sirolimus-eluting stents on long-term outcome in diabetic patients].
Journal: Zhonghua xin xue guan bing za zhi 20050501
Title: [Clinical and angiographic follow-up study of sirolimus-eluting stent for treatment of in-stent restenosis].
Journal: Zhonghua xin xue guan bing za zhi 20050501
Title: [Rapamycin].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050501
Title: Rapamycin ameliorates experimental autoimmune myocarditis.
Journal: International heart journal 20050501
Title: Assessment of microvascular perfusion changes in a rat breast tumor model using SonoVue to monitor the effects of different anti-angiogenic therapies.
Journal: Academic radiology 20050501
Title: Delayed occurrence of restenosis in drug eluting stents: an evidence of delayed healing.
Journal: The Journal of the Association of Physicians of India 20050501
Title: TOR kinase pathway and 14-3-3 proteins regulate glucose-induced expression of HXT1, a yeast low-affinity glucose transporter.
Journal: Yeast (Chichester, England) 20050430
Title: Effects of immunosuppressants on induction of regulatory cells after intratracheal delivery of alloantigen.
Journal: Transplantation 20050427
Title: The effect of 2-gram versus 1-gram concentration controlled mycophenolate mofetil on renal transplant outcomes using sirolimus-based calcineurin inhibitor drug-free immunosuppression.
Journal: Transplantation 20050427
Title: Immunosuppressive therapy with everolimus can be associated with potentially life-threatening lingual angioedema.
Journal: Transplantation 20050427
Title: Impact of sirolimus on early graft function after deceased-donor kidney transplantation.
Journal: Transplantation 20050427
Title: Elucidating the substrate specificity and condensation domain activity of FkbP, the FK520 pipecolate-incorporating enzyme.
Journal: Biochemistry 20050426
Title: Letter regarding article by Sawhney et al, 'treatment of left anterior descending coronary artery disease with sirolimus-eluting stents'.
Journal: Circulation 20050426
Title: Effectiveness and safety of sirolimus-eluting stents in the treatment of restenosis after coronary stent placement.
Journal: Circulation 20050426
Title: Zinc induces neurofilament phosphorylation independent of p70 S6 kinase in N2a cells.
Journal: Neuroreport 20050425
Title: The yeast eIF4E-associated protein Eap1p attenuates GCN4 translation upon TOR-inactivation.
Journal: FEBS letters 20050425
Title: [Hemosiderophages in respiratory secretions. Biological significance and clinical utility].
Journal: Medicina clinica 20050423
Title: Activation of a phytopathogenic bacterial effector protein by a eukaryotic cyclophilin.
Journal: Science (New York, N.Y.) 20050422
Title: Pharmacokinetics of the immunosuppressant everolimus in maintenance renal transplant patients.
Journal: European journal of medical research 20050420
Title: Cost-effectiveness of drug-eluting stents: if only all things were equal.
Journal: The Medical journal of Australia 20050418
Title: Phosphorylated osteopontin promotes migration of human choriocarcinoma cells via a p70 S6 kinase-dependent pathway.
Journal: Journal of cellular biochemistry 20050415
Title: Complete remission of postransplant lung metastases from hepatocellular carcinoma under therapy with sirolimus and mycophenolate mofetil.
Journal: Transplantation 20050415
Title: Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ras.
Journal: Cancer research 20050415
Title: Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors.
Journal: Cancer research 20050415
Title: The role of p70S6K in hepatic stellate cell collagen gene expression and cell proliferation.
Journal: The Journal of biological chemistry 20050408
Title: Adjusted indirect comparison of intracoronary drug-eluting stents: evidence from a metaanalysis of randomized bare-metal-stent-controlled trials.
Journal: International journal of cardiology 20050408
Title: Characterization of the FKBP.rapamycin.FRB ternary complex.
Journal: Journal of the American Chemical Society 20050406
Title: Treatment of saphenous vein graft lesions with drug-eluting stents: immediate and midterm outcome.
Journal: Journal of the American College of Cardiology 20050405
Title: Stent underexpansion and residual reference segment stenosis are related to stent thrombosis after sirolimus-eluting stent implantation: an intravascular ultrasound study.
Journal: Journal of the American College of Cardiology 20050405
Title: The unrestricted use of paclitaxel- versus sirolimus-eluting stents for coronary artery disease in an unselected population: one-year results of the Taxus-Stent Evaluated at Rotterdam Cardiology Hospital (T-SEARCH) registry.
Journal: Journal of the American College of Cardiology 20050405
Title: Strain-induced vascular endothelial cell proliferation requires PI3K-dependent mTOR-4E-BP1 signal pathway.
Journal: American journal of physiology. Heart and circulatory physiology 20050401
Title: The impact of the introduction of drug-eluting stents on the clinical practice of surgical and percutaneous treatment of coronary artery disease.
Journal: European heart journal 20050401
Title: Inhibition of neointima formation by a novel drug-eluting stent system that allows for dose-adjustable, multiple, and on-site stent coating.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20050401
Title: The Snf1 protein kinase and Sit4 protein phosphatase have opposing functions in regulating TATA-binding protein association with the Saccharomyces cerevisiae INO1 promoter.
Journal: Genetics 20050401
Title: mTOR-targeted therapy of cancer with rapamycin derivatives.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20050401
Title: Therapeutic drug monitoring for everolimus in kidney transplantation using 12-month exposure, efficacy, and safety data.
Journal: Clinical transplantation 20050401
Title: The effect of sirolimus on sex hormone levels of male renal transplant recipients.
Journal: Clinical transplantation 20050401
Title: Rapamycin in patients with chronic renal allograft dysfunction.
Journal: Clinical transplantation 20050401
Title: Gastrointestinal hemorrhage due to complicated gastroduodenal ulcer disease in liver transplant patients taking sirolimus.
Journal: Clinical transplantation 20050401
Title: Cytomegalovirus prophylaxis with valganciclovir in African-American renal allograft recipients based on donor/recipient serostatus.
Journal: Clinical transplantation 20050401
Title: Selectin blockade plus therapy with low-dose sirolimus and cyclosporin a prevent brain death-induced renal allograft dysfunction.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050401
Title: Assessing analytical specificity in quantitative analysis using tandem mass spectrometry.
Journal: Clinical biochemistry 20050401
Title: One year cost effectiveness of sirolimus eluting stents compared with bare metal stents in the treatment of single native de novo coronary lesions: an analysis from the RAVEL trial.
Journal: Heart (British Cardiac Society) 20050401
Title: Unusual post-transplantation recurrence of focal segmental glomerulosclerosis which resolved with cyclosporine but not with sirolimus.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050401
Title: Certican (Everolimus) in heart transplantation: from clinical trial to clinical experience. Proceedings of a meeting, Vienna, Austria, September 9, 2004.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401
Title: From clinical trials to clinical practice: an overview of Certican (everolimus) in heart transplantation.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401
Title: Prevention of cardiac allograft vasculopathy with Certican (everolimus): the Stanford University experience within the Certican Phase III clinical trial.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401
Title: Recommendations for use of Certican (everolimus) after heart transplantation: results from a German and Austrian Consensus Conference.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401
Title: Clinical experience with Certican (everolimus) in de novo heart transplant patients at the Deutsches Herzzentrum Berlin.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401
Title: Clinical experience with Certican (everolimus) in maintenance heart transplant patients at the Medical University of Vienna.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401
Title: Use of sirolimus and low-dose calcineurin inhibitor in lung transplant recipients with renal impairment: results of a controlled pilot study.
Journal: Kidney international 20050401
Title: Rapid response to rituximab in a pediatric liver transplant recipient with post-transplant lymphoproliferative disease and maintenance with sirolimus monotherapy.
Journal: Pediatric transplantation 20050401
Title: Efficacy and safety of oral sirolimus to inhibit in-stent intimal hyperplasia.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050401
Title: Another attempt to deal with restenosis.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050401
Title: Drug eluting stents: case study in the acceptance of a new medical technology.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050401
Title: Results and follow-up after implantation of four or more sirolimus-eluting stents in the same patient.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050401
Title: Reversal of diabetes in pancreatectomized pigs after transplantation of neonatal porcine islets.
Journal: Diabetes 20050401
Title: Effective use of liquid chromatography-mass spectrometry (LC/MS) in the routine clinical laboratory for monitoring sirolimus, tacrolimus, and cyclosporine.
Journal: Therapeutic drug monitoring 20050401
Title: Validation of a practical liquid chomatography with ultraviolet detection method for quantification of whole-blood everolimus in a clinical TDM laboratory.
Journal: Therapeutic drug monitoring 20050401
Title: Successful use in lung transplantation of an immunosuppressive regimen aimed at reducing target blood levels of sirolimus and tacrolimus.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401
Title: Kidney transplantation under minimal immunosuppression after pretransplant lymphoid depletion with Thymoglobulin or Campath.
Journal: Journal of the American College of Surgeons 20050401
Title: Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors.
Journal: Cancer research 20050401
Title: Effects of the mammalian target of rapamycin inhibitor CCI-779 used alone or with chemotherapy on human prostate cancer cells and xenografts.
Journal: Cancer research 20050401
Title: Treatment of psoriasis with topical sirolimus: preclinical development and a randomized, double-blind trial.
Journal: The British journal of dermatology 20050401
Title: [Islet cell transplantation].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20050401
Title: Sirolimus improves renal function in cardiac transplantation.
Journal: Transplantation proceedings 20050401
Title: Graft function, cardiovascular risk factors, and sex hormones in renal transplant recipients on an immunosuppressive regimen of everolimus, reduced dose of cyclosporine, and basiliximab.
Journal: Transplantation proceedings 20050401
Title: [Research progress of the drug-coated stents].
Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20050401
Title: Right atrial thrombosis in a heart transplant recipient after initiation of sirolimus.
Journal: Acta cardiologica 20050401
Title: Drug-eluting stents. The third revolution in percutaneous coronary intervention.
Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20050401
Title: mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma.
Journal: Neoplasia (New York, N.Y.) 20050401
Title: Macrophages rapidly transfer pathogens from lipid raft vacuoles to autophagosomes.
Journal: Autophagy 20050401
Title: Sirolimus for Kaposi's sarcoma in renal-transplant recipients.
Journal: The New England journal of medicine 20050331
Title: Immunosuppressive drugs and the risk of cancer after organ transplantation.
Journal: The New England journal of medicine 20050331
Title: Effect of GLP-1 on glucose transport and its cell signalling in human myocytes.
Journal: Regulatory peptides 20050330
Title: Design of an intein that can be inhibited with a small molecule ligand.
Journal: Journal of the American Chemical Society 20050330
Title: Sirolimus-eluting stents to abolish intimal hyperplasia and improve flow in porcine arteriovenous grafts: a 4-week follow-up study.
Journal: Circulation 20050329
Title: Drug interaction between itraconazole and sirolimus in a primary renal allograft recipient.
Journal: Transplantation 20050327
Title: Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway.
Journal: The Journal of biological chemistry 20050325
Title: Characterization of a conserved C-terminal motif (RSPRR) in ribosomal protein S6 kinase 1 required for its mammalian target of rapamycin-dependent regulation.
Journal: The Journal of biological chemistry 20050325
Title: The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation.
Journal: Cell 20050325
Title: Short- and long-term clinical outcome after drug-eluting stent implantation for the percutaneous treatment of left main coronary artery disease: insights from the Rapamycin-Eluting and Taxus Stent Evaluated At Rotterdam Cardiology Hospital registries (RESEARCH and T-SEARCH).
Journal: Circulation 20050322
Title: [Study of the effects of immunosuppressive agents on human islet cells in vitro].
Journal: Zhonghua yi xue za zhi 20050316
Title: Antileukemic activity of rapamycin in acute myeloid leukemia.
Journal: Blood 20050315
Title: Comparison of C-reactive protein levels after coronary stenting with bare metal versus sirolimus-eluting stents.
Journal: The American journal of cardiology 20050315
Title: In-hospital and nine-month outcome of treatment of coronary bifurcational lesions with sirolimus-eluting stent.
Journal: The American journal of cardiology 20050315
Title: Thirty-day incidence and six-month clinical outcome of thrombotic stent occlusion after bare-metal, sirolimus, or paclitaxel stent implantation.
Journal: Journal of the American College of Cardiology 20050315
Title: Drug-eluting stent thrombosis: results from a pooled analysis including 10 randomized studies.
Journal: Journal of the American College of Cardiology 20050315
Title: Rapamycin inhibits ezrin-mediated metastatic behavior in a murine model of osteosarcoma.
Journal: Cancer research 20050315
Title: A selective small molecule c-MET Inhibitor, PHA665752, cooperates with rapamycin.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050315
Title: [Successful treatment of a severe case of idiopathic pulmonary fibrosis with rapamycin].
Journal: Medizinische Klinik (Munich, Germany : 1983) 20050315
Title: Sirolimus inhibits growth of human hepatoma cells alone or combined with tacrolimus, while tacrolimus promotes cell growth.
Journal: World journal of gastroenterology 20050314
Title: Clinical and angiographic follow-up study of sirolimus-eluting stent for treatment of in-stent restenosis.
Journal: Chinese medical journal 20050305
Title: Resistance exercise increases muscle protein synthesis and translation of eukaryotic initiation factor 2Bepsilon mRNA in a mammalian target of rapamycin-dependent manner.
Journal: The Journal of biological chemistry 20050304
Title: Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes.
Journal: Endocrinology 20050301
Title: Efficacy of a rapamycin analog (CCI-779) and IFN-gamma in tuberous sclerosis mouse models.
Journal: Genes, chromosomes & cancer 20050301
Title: HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050301
Title: Mouse embryonic stem cells and preimplantation embryos require signaling through the phosphatidylinositol 3-kinase pathway to suppress apoptosis.
Journal: Molecular reproduction and development 20050301
Title: Small molecule control of pre-mRNA splicing.
Journal: RNA (New York, N.Y.) 20050301
Title: Everolimus and basiliximab permit suppression by human CD4+CD25+ cells in vitro.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050301
Title: Consequences of genetic polymorphisms for sirolimus requirements after renal transplant in patients on primary sirolimus therapy.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050301
Title: Constitutive activation of phosphatidyl-inositide 3 kinase contributes to the survival of Hodgkin's lymphoma cells through a mechanism involving Akt kinase and mTOR.
Journal: The Journal of pathology 20050301
Title: Mechanism of zinc-induced phosphorylation of p70 S6 kinase and glycogen synthase kinase 3beta in SH-SY5Y neuroblastoma cells.
Journal: Journal of neurochemistry 20050301
Title: Immunosuppression in liver transplantation: beyond calcineurin inhibitors.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20050301
Title: Meta-analysis comparing drug-eluting stents with bare metal stents.
Journal: The American journal of cardiology 20050301
Title: Maintenance of long-term clinical benefit with sirolimus-eluting coronary stents: three-year results of the RAVEL trial.
Journal: Circulation 20050301
Title: Activity of sirolimus in patients with myelodysplastic syndrome--results of a pilot study.
Journal: British journal of haematology 20050301
Title: Clinical application of sirolimus in renal transplantation: an update.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050301
Title: Sirolimus quantification by high-performance liquid chromatography with ultraviolet detection.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050301
Title: Efficacy of rapamycin in patient with juvenile rheumatoid arthritis.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050301
Title: Firefly luciferase enzyme fragment complementation for imaging in cells and living animals.
Journal: Analytical chemistry 20050301
Title: Novel site-specific systemic delivery of Rapamycin with perfluorobutane gas microbubble carrier reduced neointimal formation in a porcine coronary restenosis model.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050301
Title: Late follow-up from RAVEL: transition from intention to observation.
Journal: Circulation 20050301
Title: Sirolimus-eluting stent treatment for isolated proximal left anterior descending artery stenoses. Results from the prospective multi-center German Cypher Registry.
Journal: Zeitschrift fur Kardiologie 20050301
Title: Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity.
Journal: Cancer research 20050301
Title: Sirolimus-eluting stents versus the superficial femoral artery: second round.
Journal: Journal of vascular and interventional radiology : JVIR 20050301
Title: Sirolimus-eluting versus bare nitinol stent for obstructive superficial femoral artery disease: the SIROCCO II trial.
Journal: Journal of vascular and interventional radiology : JVIR 20050301
Title: [Treatment of lesions with a high risk of stenosis. Comparative study in 300 patients of rapamycin- and Paclitaxel-eluting polymer-based stents, and bare metal stents].
Journal: Revista espanola de cardiologia 20050301
Title: Rapamycin and UCN-01 synergistically induce apoptosis in human leukemia cells through a process that is regulated by the Raf-1/MEK/ERK, Akt, and JNK signal transduction pathways.
Journal: Molecular cancer therapeutics 20050301
Title: Restenosis and drug-eluting stents.
Journal: The Mount Sinai journal of medicine, New York 20050301
Title: LY294002 and rapamycin co-operate to inhibit T-cell proliferation.
Journal: British journal of pharmacology 20050301
Title: Effect of multiple-dose erythromycin on everolimus pharmacokinetics.
Journal: European journal of clinical pharmacology 20050301
Title: A combination of anergic cells' adoptive transfer and rapamycin therapy prolongs cardiac allograft survival in mice.
Journal: Scandinavian journal of immunology 20050301
Title: Signal transduction pathways in androgen-dependent and -independent prostate cancer cell proliferation.
Journal: Endocrine-related cancer 20050301
Title: Sirolimus: a new option in transplantation.
Journal: Expert opinion on pharmacotherapy 20050301
Title: Recurrence of migraine with aura due to tacrolimus therapy in a liver transplant recipient successfully treated with sirolimus substitution.
Journal: Headache 20050301
Title: Sirolimus in pediatric renal transplantation.
Journal: Transplantation proceedings 20050301
Title: Sirolimus-based therapy with or without cyclosporine: long-term follow-up in renal transplant patients.
Journal: Transplantation proceedings 20050301
Title: A randomized trial of steroid avoidance in renal transplant patients treated with everolimus and cyclosporine.
Journal: Transplantation proceedings 20050301
Title: Corticosteroid avoidance ameliorates lymphocele formation and wound healing complications associated with sirolimus therapy.
Journal: Transplantation proceedings 20050301
Title: Rabbit antithymocyte globulin: a postoperative risk factor for sirolimus-treated renal transplant patients?
Journal: Transplantation proceedings 20050301
Title: Addition of sirolimus to cyclosporine in long-term kidney transplant recipients to withdraw steroid.
Journal: Transplantation proceedings 20050301
Title: The effect of rapamycin on the healing of the ureteric anastomosis and wound healing.
Journal: Transplantation proceedings 20050301
Title: Effect of rapamycin on the healing of the bile duct.
Journal: Transplantation proceedings 20050301
Title: Severe limb lymphedema in sirolimus-treated patients.
Journal: Transplantation proceedings 20050301
Title: Cyclosporine and rapamycin act in a synergistic and dose-dependent manner in a model of immunosuppressant-induced kidney damage.
Journal: Transplantation proceedings 20050301
Title: Sirolimus delays recovery from posttransplant renal failure in kidney graft recipients.
Journal: Transplantation proceedings 20050301
Title: Pharmacokinetics of mycophenolic acid in kidney transplant patients receiving sirolimus versus cyclosporine.
Journal: Transplantation proceedings 20050301
Title: No-load sirolimus with tacrolimus and steroids is safe and effective in renal transplantation.
Journal: Transplantation proceedings 20050301
Title: Regression of Kaposi's sarcoma in renal graft recipients after conversion to sirolimus treatment.
Journal: Transplantation proceedings 20050301
Title: Graft survival and immune regulation of pancreas allograft recipients induced with thymoglobulin, sirolimus, and cyclosporine.
Journal: Transplantation proceedings 20050301
Title: Impact of a sirolimus/tacrolimus-based immunosuppressive regimen on kidney function after islet transplantation.
Journal: Transplantation proceedings 20050301
Title: Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20050301
Title: Primary stenting of occluded native coronary arteries II--rationale and design of the PRISON II study: a randomized comparison of bare metal stent implantation with sirolimus-eluting stent implantation for the treatment of chronic total coronary occlusions.
Journal: American heart journal 20050301
Title: Cutaneous adverse events in renal transplant recipients receiving sirolimus-based therapy.
Journal: Transplantation 20050227
Title: High-performance liquid chromatography with ultraviolet detection for therapeutic drug monitoring of everolimus.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225
Title: Potent inhibitory effect of sirolimus on circulating vascular progenitor cells.
Journal: Circulation 20050222
Title: [Recent progress and problems in percutaneous coronary intervention].
Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20050220
Title: Specific interactions of PP2A and PP2A-like phosphatases with the yeast PTPA homologues, Ypa1 and Ypa2.
Journal: The Biochemical journal 20050215
Title: Activation of the p70 S6 kinase by all-trans-retinoic acid in acute promyelocytic leukemia cells.
Journal: Blood 20050215
Title: Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer.
Journal: Blood 20050215
Title: Intravascular ultrasound assessment of lesions with target vessel failure after sirolimus-eluting stent implantation.
Journal: The American journal of cardiology 20050215
Title: Early and mid-term results of drug-eluting stent implantation in unprotected left main.
Journal: Circulation 20050215
Title: Maintenance immunosuppression use and the associated risk of avascular necrosis after kidney transplantation in the United States.
Journal: Transplantation 20050215
Title: Drug-eluting stents for diabetes mellitus: a rush to judgment?
Journal: Journal of the American College of Cardiology 20050215
Title: Exceptional circumstances and heart transplantation.
Journal: The New Zealand medical journal 20050211
Title: REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase.
Journal: Oncogene 20050210
Title: [New generation of percutaneous coronary intervention: drug-eluting stent].
Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20050210
Title: Scientists hopeful as they uncover molecular clues to prostate cancer.
Journal: Journal of the National Cancer Institute 20050202
Title: EGF receptor transactivation mediates ANG II-stimulated mitogenesis in intestinal epithelial cells through the PI3-kinase/Akt/mTOR/p70S6K1 signaling pathway.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20050201
Title: Prevention of lethal acute GVHD with an agonistic CD28 antibody and rapamycin.
Journal: Blood 20050201
Title: Regulation of leucine uptake by tor1+ in Schizosaccharomyces pombe is sensitive to rapamycin.
Journal: Genetics 20050201
Title: Rapamycin attenuates vascular wall inflammation and progenitor cell promoters after angioplasty.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050201
Title: Application of commercial calibrators for the analysis of immunosuppressant drugs in whole blood.
Journal: Clinical chemistry 20050201
Title: Complete assignments of the 1H and 13C resonances of 40-epi-(N1-tetrazolyl)-rapamycin and revised 13C assignments for rapamycin.
Journal: Magnetic resonance in chemistry : MRC 20050201
Title: Effects of maternal starvation on hepatocyte proliferation in the late gestation fetal rat.
Journal: Pediatric research 20050201
Title: Rapamycin-treated, alloantigen-pulsed host dendritic cells induce ag-specific T cell regulation and prolong graft survival.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050201
Title: Inhibition of endogenous SHIP2 ameliorates insulin resistance caused by chronic insulin treatment in 3T3-L1 adipocytes.
Journal: Diabetologia 20050201
Title: Large coronary artery aneurysms following sirolimus eluting stent implantation.
Journal: Heart (British Cardiac Society) 20050201
Title: Economic evaluation of everolimus vs. azathioprine at one year after de novo heart transplantation.
Journal: Clinical transplantation 20050201
Title: An open-label, pilot study evaluating the safety and efficacy of converting from calcineurin inhibitors to sirolimus in established renal allograft recipients with moderate renal insufficiency.
Journal: Clinical transplantation 20050201
Title: Improved renal function in de novo renal transplant patients on sirolimus maintenance therapy following discontinuation of cyclosporine.
Journal: Therapeutic drug monitoring 20050201
Title: The portal immunosuppressive storm: relevance to islet transplantation?
Journal: Therapeutic drug monitoring 20050201
Title: Gastrointestinal leukocytoclastic vasculitis: an adverse effect of sirolimus.
Journal: Pediatric transplantation 20050201
Title: Inhibitory effect of rapamycin on corneal neovascularization in vitro and in vivo.
Journal: Investigative ophthalmology & visual science 20050201
Title: Indefinite survival of neonatal porcine islet xenografts by simultaneous targeting of LFA-1 and CD154 or CD45RB.
Journal: Diabetes 20050201
Title: Cypher drug-eluting stent treatment of tibioperoneal obstructive disease: a case report.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050201
Title: Beware the sirens' call.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050201
Title: Is overdilatation of 3.0 mm sirolimus-eluting stent associated with a higher restenosis rate?
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050201
Title: Sirolimus-eluting stent implantation for unprotected left main coronary artery stenosis: comparison with bare metal stent implantation.
Journal: Journal of the American College of Cardiology 20050201
Title: Percutaneous coronary intervention and drug-eluting stents.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050201
Title: Economic evaluation of sirolimus-eluting stents.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050201
Title: The dollars and sense of drug-eluting stents.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050201
Title: Use of everolimus-eluting stent with a bioresorbable polymer coating for treatment of recurrent in-stent restenosis.
Journal: The Journal of invasive cardiology 20050201
Title: Rotational ablation of an unexpandable sirolimus-eluting stent.
Journal: The Journal of invasive cardiology 20050201
Title: Rapamycin rescue therapy in patients after kidney transplantation: first clinical experience.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050201
Title: Rapamycin treatment is associated with an increased apoptosis rate in experimental vein grafts.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20050201
Title: Rapamycin (sirolimus) as a steroid-sparing agent in dermatomyositis.
Journal: Journal of the American Academy of Dermatology 20050201
Title: Sirolimus immunosuppression in pediatric heart transplant recipients: a single-center experience.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050201
Title: How drug-eluting stents keep coronary blood flowing.
Journal: Nursing 20050201
Title: Transcriptional profiles in peripheral blood mononuclear cells prognostic of clinical outcomes in patients with advanced renal cell carcinoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050201
Title: Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members.
Journal: Molecular cancer therapeutics 20050201
Title: Assessment of glomerular and tubular functions in renal transplant patients receiving cyclosporine A in combination with either sirolimus or everolimus.
Journal: Clinical nephrology 20050201
Title: PKB/Akt mediates radiosensitization by the signaling inhibitor LY294002 in human malignant gliomas.
Journal: Journal of neuro-oncology 20050201
Title: Stent competition helps prices.
Journal: Hospital material[dollar sign] management 20050201
Title: Patent infringement.
Journal: Nature reviews. Drug discovery 20050201
Title: Long-term inducible gene expression in the eye via adeno-associated virus gene transfer in nonhuman primates.
Journal: Human gene therapy 20050201
Title: Effects of rapamycin on the epithelial-to-mesenchymal transition of human peritoneal mesothelial cells.
Journal: The International journal of artificial organs 20050201
Title: Sirolimus-eluting stent implantation for chronic total occlusion of the left main coronary artery.
Journal: Journal of interventional cardiology 20050201
Title: Coronary restenosis after implantation of drug-eluting stents.
Journal: Minerva cardioangiologica 20050201
Title: Can oral sirolimus therapy prevent in-stent restenosis?
Journal: Nature clinical practice. Cardiovascular medicine 20050201
Title: Sirolimus and ACE-inhibitors: a note of caution.
Journal: Transplantation 20050127
Title: Relationship of late loss in lumen diameter to coronary restenosis in sirolimus-eluting stents.
Journal: Circulation 20050125
Title: Alternative phospholipase D/mTOR survival signal in human breast cancer cells.
Journal: Oncogene 20050120
Title: A prospective randomized comparison between paclitaxel and sirolimus stents in the real world of interventional cardiology: the TAXi trial.
Journal: Journal of the American College of Cardiology 20050118
Title: Altered trafficking of CD8+ memory T cells after implantation of rapamycin-eluting stents in patients with coronary artery disease.
Journal: Immunology letters 20050115
Title: Impact of sirolimus-eluting stent on the outcome of patients with chronic total occlusions.
Journal: The American journal of cardiology 20050115
Title: Impact of baseline renal function on mortality after percutaneous coronary intervention with sirolimus-eluting stents or bare metal stents.
Journal: The American journal of cardiology 20050115
Title: Interleukin-12-induced interferon-gamma production by human peripheral blood T cells is regulated by mammalian target of rapamycin (mTOR).
Journal: The Journal of biological chemistry 20050114
Title: Sirolimus-eluting stent or paclitaxel-eluting stent vs balloon angioplasty for prevention of recurrences in patients with coronary in-stent restenosis: a randomized controlled trial.
Journal: JAMA 20050112
Title: [Nephrology].
Journal: Revue medicale suisse 20050105
Title: Direct stenting of native de novo coronary artery lesions with the sirolimus-eluting stent: a post hoc subanalysis of the pooled E- and C-SIRIUS trials.
Journal: Journal of the American College of Cardiology 20050104
Title: Effects of rapamycin on cardiac and skeletal muscle contraction and crossbridge cycling.
Journal: The Journal of pharmacology and experimental therapeutics 20050101
Title: Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts.
Journal: Molecular endocrinology (Baltimore, Md.) 20050101
Title: An intramolecular ionic hydrogen bond stabilizes a cis amide bond rotamer of a ring-opened rapamycin-degradation product.
Journal: Magnetic resonance in chemistry : MRC 20050101
Title: Effects of rapamycin in the Eker rat model of tuberous sclerosis complex.
Journal: Pediatric research 20050101
Title: Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease.
Journal: Journal of the American Society of Nephrology : JASN 20050101
Title: Monitoring of immunosuppressive therapy in renal transplanted patients.
Journal: Contributions to nephrology 20050101
Title: Decreased Cytomegalovirus infection after antilymphocyte therapy in sirolimus-treated renal transplant patients.
Journal: International immunopharmacology 20050101
Title: Nonnephrotoxic immunosuppression in patients after liver transplantation.
Journal: International immunopharmacology 20050101
Title: Center experience in liver transplantation (LTX): management of dermal side effects caused by sirolimus.
Journal: International immunopharmacology 20050101
Title: Immunosuppressant drug monitoring: is the laboratory meeting clinical expectations?
Journal: The Annals of pharmacotherapy 20050101
Title: A meta-analysis of clinical trials of paclitaxel- and sirolimus-eluting stents in patients with obstructive coronary artery disease.
Journal: British journal of clinical pharmacology 20050101
Title: Immunosuppression: towards a logical approach in liver transplantation.
Journal: Clinical and experimental immunology 20050101
Title: CD28 regulates the translation of Bcl-xL via the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050101
Title: Strategies for minimizing immunosuppression in kidney transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050101
Title: Early cyclosporine withdrawal from a sirolimus-based regimen results in better renal allograft survival and renal function at 48 months after transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050101
Title: Dosing of rapamycin is critical to achieve an optimal antiangiogenic effect against cancer.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20050101
Title: Cardiovascular risk profile in patients treated with sirolimus after renal transplantation.
Journal: Kidney international. Supplement 20050101
Title: Sirolimus- and paclitaxel-eluting stents in comparison with balloon angioplasty for treatment of in-stent restenosis.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050101
Title: Angiographic results of the first human experience with everolimus-eluting stents for the treatment of coronary lesions (the FUTURE I trial).
Journal: The American journal of cardiology 20050101
Title: Mammalian target of rapamycin (mTOR) inhibition in chronic lymphocytic B-cell leukemia: a new therapeutic option.
Journal: Leukemia & lymphoma 20050101
Title: A novel technique for on-capillary preconcentration of anionic compounds applied to the trace analysis of rapamycin in human blood by capillary electrophoresis.
Journal: Electrophoresis 20050101
Title: Rapamycin (sirolimus) for treatment of chronic graft-versus-host disease.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050101
Title: Stent implantation activates RhoA in human arteries: inhibitory effect of rapamycin.
Journal: Journal of vascular research 20050101
Title: Nephrotoxicity of rapamycin: an emerging problem in clinical medicine.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050101
Title: De novo thrombotic microangiopathy following treatment with sirolimus: report of two cases.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050101
Title: Immunophilin ligands FK506 and cyclosporine A improve neurologic and histopathologic outcome after transient spinal cord ischemia in rabbits.
Journal: The Journal of thoracic and cardiovascular surgery 20050101
Title: A multicenter pilot study of early (4-day) steroid cessation in renal transplant recipients under simulect, tacrolimus and sirolimus.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050101
Title: Sirolimus impairs improvement of the gonadal function after renal transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050101
Title: Population pharmacokinetics of CCI-779: correlations to safety and pharmacogenomic responses in patients with advanced renal cancer.
Journal: Clinical pharmacology and therapeutics 20050101
Title: Sirolimus-eluting stents for the treatment of atherosclerotic ostial lesions.
Journal: The Journal of invasive cardiology 20050101
Title: Sirolimus-eluting stents for the treatment of atherosclerotic ostial lesions.
Journal: The Journal of invasive cardiology 20050101
Title: Determining sensitivity to rapamycin and its analogues in breast cancer patients.
Journal: Breast cancer research : BCR 20050101
Title: Tor and cyclic AMP-protein kinase A: two parallel pathways regulating expression of genes required for cell growth.
Journal: Eukaryotic cell 20050101
Title: The Coronary Artery Revascularisation in Diabetes (CARDia) trial: background, aims, and design.
Journal: American heart journal 20050101
Title: Effects of conversion from sirolimus oral solution to tablets in stable Taiwanese renal transplant recipients.
Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20050101
Title: Choosing a drug-eluting stent: a comparison between CYPHER and TAXUS.
Journal: Reviews in cardiovascular medicine 20050101
Title: Safety and efficacy of drug-eluting stents.
Journal: Reviews in cardiovascular medicine 20050101
Title: Coping with rejection: immunosuppressants and organ transplantation.
Journal: Drug discovery today 20050101
Title: Benefit-risk assessment of sirolimus in renal transplantation.
Journal: Drug safety 20050101
Title: Sphingosine-1-phosphate-induced smooth muscle cell migration involves the mammalian target of rapamycin.
Journal: Journal of vascular surgery 20050101
Title: Mechanisms of action of rapamycin in gliomas.
Journal: Neuro-oncology 20050101
Title: Cardiovascular device development: drug-eluting stents and implantable devices for the treatment of heart failure--the view from the Circulatory System Advisory Panel.
Journal: American journal of therapeutics 20050101
Title: [New immunodepressant drugs for the prevention and control of kidney transplant rejection].
Journal: Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20050101
Title: Protein synthesis-dependent LTP in isolated dendrites of CA1 pyramidal cells.
Journal: Hippocampus 20050101
Title: Prograf produces a molecular environment favoring antifibrosis, an effect reversed by the addition of rapamune.
Journal: Transplantation proceedings 20050101
Title: Immunological evaluation of combination therapy with tacrolimus and sirolimus on long-term allograft survival in nonhuman primates.
Journal: Transplantation proceedings 20050101
Title: Predominant inhibition of interleukin-6 synthesis in patient-specific endothelial cells by mTOR inhibitors below a concentration range where cell proliferation is affected and mitotic arrest takes place.
Journal: Transplantation proceedings 20050101
Title: Sirolimus-mediated prolongation of rat cardiac allograft survival is enhanced by beta1 integrin very late antigen-4 blockade.
Journal: Transplantation proceedings 20050101
Title: Mycophenolate mofetil inhibits intimal hyperplasia and attenuates the expression of genes favouring smooth muscle cell proliferation and migration.
Journal: Transplantation proceedings 20050101
Title: A microparticle enzyme immunoassay to measure sirolimus.
Journal: Transplantation proceedings 20050101
Title: Involvement of mitogen-stimulated p70-S6 kinase in the development of sensitization to the methamphetamine-induced rewarding effect in rats.
Journal: Neuroscience 20050101
Title: Medium-term results from the clinical and angiographic follow-up of patients after angioplasty and implantation of sirolimus-eluting stents.
Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20050101
Title: The use of drug-eluting stents in everyday clinical practice: can the results of randomised trials be achieved in the 'real world'?
Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20050101
Title: Inhibition of different intracellular signal cascades in human pancreatic cancer cells.
Journal: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20050101
Title: Inhibition of mTOR suppresses experimental liver tumours.
Journal: Anticancer research 20050101
Title: [The first experience with sirolimus (Rapamune) after kidney transplantation in Lithuania].
Journal: Medicina (Kaunas, Lithuania) 20050101
Title: Sirolimus-eluting stents for treatment of in-stent restenosis: immediate and late results.
Journal: Texas Heart Institute journal 20050101
Title: Sirolimus increases tissue factor expression but not activity in cultured human vascular smooth muscle cells.
Journal: BMC cardiovascular disorders 20050101
Title: Percutaneous therapy of bifurcation lesions with drug-eluting stent implantation: the Culotte technique revisited.
Journal: International journal of cardiovascular interventions 20050101
Title: Therapeutic targeting of multiple signaling pathways in malignant pleural mesothelioma.
Journal: Oncology 20050101
Title: Sirolimus: the evidence for clinical pharmacokinetic monitoring.
Journal: Clinical pharmacokinetics 20050101
Title: Overcoming cisplatin resistance by mTOR inhibitor in lung cancer.
Journal: Molecular cancer 20050101
Title: Impaired glomerular and tubular function as a short-term effect of sirolimus treatment in the rat.
Journal: American journal of nephrology 20050101
Title: Lack of effect of rapamycin in anti-CCP antibody production in a rheumatoid arthritis kidney allograft recipient.
Journal: Clinical and experimental rheumatology 20050101
Title: Direct stenting with sirolimus-eluting stents.
Journal: The American heart hospital journal 20050101
Title: Treatment of double vessel coronary artery disease by totally endoscopic bypass surgery and drug-eluting stent placement in one simultaneous hybrid session.
Journal: The heart surgery forum 20050101
Title: Impressive regression of primary liver cancer after treatment with sirolimus.
Journal: Acta oncologica (Stockholm, Sweden) 20050101
Title: [Acute, idiopathic, bilateral uveitis with periphlebitis--case report].
Journal: Klinika oczna 20050101
Title: Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis.
Journal: Cardiology 20050101
Title: Treating breast cancer through novel inhibitors of the phosphatidylinositol 3'-kinase pathway.
Journal: Breast cancer research : BCR 20050101
Title: Calcineurin inhibitor-free immunosuppression in renal transplantation.
Journal: Transplantation proceedings 20050101
Title: Conversion to sirolimus in a population of kidney and kidney-pancreas transplant recipients.
Journal: Transplantation proceedings 20050101
Title: Combined use of tacrolimus and sirolimus in de novo renal transplant patients: current data.
Journal: Transplantation proceedings 20050101
Title: Is sirolimus responsible for proteinuria?
Journal: Transplantation proceedings 20050101
Title: Sirolimus-associated acute respiratory distress syndrome in a renal transplant recipient.
Journal: Transplantation proceedings 20050101
Title: Evaluation of a new immunoassay to measure sirolimus blood concentrations compared to a tandem mass-spectrometric chromatographic analysis.
Journal: Transplantation proceedings 20050101
Title: Determination of rapamycin: quantification of the sodiated species by an ion trap mass spectrometer as an alternative to the ammoniated complex analysis by triple quadrupole.
Journal: Rapid communications in mass spectrometry : RCM 20050101
Title: The mammalian target of the rapamycin (mTOR) kinase pathway: its role in tumourigenesis and targeted antitumour therapy.
Journal: Cellular & molecular biology letters 20050101
Title: [Evidences in immunosuppression in the maintenance of renal transplantation].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20050101
Title: Acute and intermediate-term procedural results using cypher stenting to treat multi-vessel coronary artery disease.
Journal: International journal of cardiovascular interventions 20050101
Title: Drug-eluting stents for the treatment of in-stent restenosis: a clinical review.
Journal: Cardiovascular revascularization medicine : including molecular interventions 20050101
Title: Segmental vessel wall shear stress and neointimal formation after sirolimus-eluting stent implantation: physiological insights in a porcine coronary model.
Journal: Cardiovascular revascularization medicine : including molecular interventions 20050101
Title: Sirolimus-induced acneiform eruption.
Journal: Dermatology (Basel, Switzerland) 20050101
Title: Drug-eluting stents: immediate and long-term results.
Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20050101
Title: What is the best contemporary treatment for in-stent restenosis?
Journal: Cardiovascular revascularization medicine : including molecular interventions 20050101
Title: Drug-eluting stents for the treatment of in-stent restenosis--'real world' double centre experience in consecutive patients.
Journal: International journal of cardiovascular interventions 20050101
Title: Successful use of sirolimus-eluting stents for treatment of ST-elevation acute myocardial infarction caused by left main coronary artery occlusion.
Journal: Texas Heart Institute journal 20050101
Title: Long-term outcome after coronary angioplasty: where do we stand?
Journal: Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20050101
Title: Effects of combined treatment with rapamycin and cotylenin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenografts.
Journal: Breast cancer research : BCR 20050101
Title: A case of giant aneurysm following percutaneous coronary intervention.
Journal: Indian heart journal 20050101
Title: [Immunosuppression for kidney transplant recipients: current strategies].
Journal: Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20050101
Title: Rapamycin inhibits platelet-derived growth factor-induced collagen, but not fibronectin, synthesis in rat mesangial cells.
Journal: Yonsei medical journal 20041231
Title: A pilot study of calcineurin inhibitors (CNIs) and steroid avoidance immunosuppressive protocol among living donor kidney transplant recipients.
Journal: Yonsei medical journal 20041231
Title: TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1.
Journal: Cell 20041229
Title: Glucose-stimulated protein synthesis in pancreatic beta-cells parallels an increase in the availability of the translational ternary complex (eIF2-GTP.Met-tRNAi) and the dephosphorylation of eIF2 alpha.
Journal: The Journal of biological chemistry 20041224
Title: The serine/threonine kinase Akt Promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase.
Journal: The Journal of biological chemistry 20041224
Title: Growth-regulated recruitment of the essential yeast ribosomal protein gene activator Ifh1.
Journal: Nature 20041223
Title: [Drug-eluting stents in coronary arteries. The risk of restenosis is drastically reduced].
Journal: Lakartidningen 20041223
Title: Systemic rapamycin inhibits retinal and choroidal neovascularization in mice.
Journal: Molecular vision 20041222
Title: Quantitative assessment of angiographic restenosis after sirolimus-eluting stent implantation in native coronary arteries.
Journal: Circulation 20041221
Title: Drug therapy in the heart transplant recipient: part II: immunosuppressive drugs.
Journal: Circulation 20041221
Title: Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages.
Journal: Cell 20041217
Title: In vivo antitumor effects of the mTOR inhibitor CCI-779 against human multiple myeloma cells in a xenograft model.
Journal: Blood 20041215
Title: Combination of the mTOR inhibitor rapamycin and CC-5013 has synergistic activity in multiple myeloma.
Journal: Blood 20041215
Title: Identification of filamin C as a new physiological substrate of PKBalpha using KESTREL.
Journal: The Biochemical journal 20041215
Title: Intravascular ultrasonic comparative analysis of degree of intimal hyperplasia produced by four different stents in the coronary arteries.
Journal: The American journal of cardiology 20041215
Title: mTOR and P70 S6 kinase expression in primary liver neoplasms.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041215
Title: Conjugation of an antibody to cross-linked fibrin for targeted delivery of anti-restenotic drugs.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20041210
Title: Sirolimus-eluting vs uncoated stents for prevention of restenosis in small coronary arteries: a randomized trial.
Journal: JAMA 20041208
Title: Stenting small coronary arteries: works in progress.
Journal: JAMA 20041208
Title: PKC-eta mediates glioblastoma cell proliferation through the Akt and mTOR signaling pathways.
Journal: Oncogene 20041202
Title: Insulin facilitation of muscle protein synthesis following resistance exercise in hindlimb-suspended rats is independent of a rapamycin-sensitive pathway.
Journal: American journal of physiology. Endocrinology and metabolism 20041201
Title: Toxin-induced tail phosphorylation of hepatocellular S6 kinase: evidence for a dual involvement of the AMP-activated protein kinase in S6 kinase regulation.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20041201
Title: Apelin (65-77) activates p70 S6 kinase and is mitogenic for umbilical endothelial cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20041201
Title: Dyslipidemia during sirolimus therapy in patients after liver transplantation.
Journal: Clinical transplantation 20041201
Title: Fate of donor kidney: laparoscopic versus open technique.
Journal: The Journal of urology 20041201
Title: Which parameter should be chosen as primary endpoint for randomized drug-eluting stent studies?
Journal: Journal of interventional cardiology 20041201
Title: Clinical experiences using everolimus-eluting stents in patients with coronary artery disease.
Journal: Journal of interventional cardiology 20041201
Title: New approaches to ostial and bifurcation lesions.
Journal: Journal of interventional cardiology 20041201
Title: Vascular brachytherapy versus sirolimus eluting stents for the treatment of in-stent restenosis: a prospective registry.
Journal: Heart (British Cardiac Society) 20041201
Title: Random mutagenesis of an essential Candida albicans gene.
Journal: Current genetics 20041201
Title: New bifurcation stenting technique: shunt stenting.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20041201
Title: Recovery of chronic renal impairment with sirolimus after lung transplantation.
Journal: The Annals of thoracic surgery 20041201
Title: Rapamycin inhibits doxorubicin-induced NF-kappaB/Rel nuclear activity and enhances the apoptosis of melanoma cells.
Journal: European journal of cancer (Oxford, England : 1990) 20041201
Title: Sirolimus with neoral versus mycophenolate mofetil with neoral is associated with decreased renal allograft survival.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041201
Title: Therapeutic drug monitoring for everolimus in heart transplant recipients based on exposure-effect modeling.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041201
Title: Mammalian target of rapamycin (mTOR) inhibitors as anti-cancer agents.
Journal: Current cancer drug targets 20041201
Title: The complexity of PTEN: mutation, marker and potential target for therapeutic intervention.
Journal: Expert opinion on therapeutic targets 20041201
Title: Therapeutic potential of target of rapamycin inhibitors.
Journal: Expert opinion on therapeutic targets 20041201
Title: Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041201
Title: Treatment of coronary artery disease in dialysis patients with sirolimus-eluting stents: 1-year clinical follow-up of a consecutive series of cases.
Journal: The Journal of invasive cardiology 20041201
Title: Sirolimus-eluting stents for percutaneous coronary intervention in acute myocardial infarction Lesson from a case-controlled comparison of bare metal versus drug-eluting stents in thrombus-laden lesions.
Journal: Zeitschrift fur Kardiologie 20041201
Title: Cap-independent protein translation is initially responsible for 4-(N-methylnitrosamino)-1-(3-pyridyl)-butanone (NNK)-induced apoptosis in normal human bronchial epithelial cells.
Journal: Journal of veterinary science 20041201
Title: Pharmacokinetics of immunosuppressants: a perspective on ethnic differences.
Journal: International journal of clinical pharmacology and therapeutics 20041201
Title: [16th EORTC-NCI-AACR symposium on new molecular targets and cancer therapeutics].
Journal: Bulletin du cancer 20041201
Title: Akt up-regulation increases resistance to microtubule-directed chemotherapeutic agents through mammalian target of rapamycin.
Journal: Molecular cancer therapeutics 20041201
Title: [Percutaneous coronary angioplasty in diabetic patients: new prospects with drug-eluting stents].
Journal: Revue medicale de Liege 20041201
Title: Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase.
Journal: Molecular and cellular biochemistry 20041201
Title: Initial experience with sirolimus and mycophenolate mofetil for renal rescue from cyclosporine nephrotoxicity after heart transplantation.
Journal: Transplantation proceedings 20041201
Title: The relative proportions of sirolimus metabolites in blood using HPLC with mass-spectrometric detection.
Journal: Transplantation proceedings 20041201
Title: Clinical relevance of sirolimus drug interactions in transplant patients.
Journal: Transplantation proceedings 20041201
Title: Sirolimus upregulates aP2 expression in human monocytes and macrophages.
Journal: Transplantation proceedings 20041201
Title: Absence of teratogenicity of sirolimus used during early pregnancy in a liver transplant recipient.
Journal: Transplantation proceedings 20041201
Title: What reimbursement for coronary revascularization with drug-eluting stents?
Journal: The European journal of health economics : HEPAC : health economics in prevention and care 20041201
Title: Exposure-response relationships and drug interactions of sirolimus.
Journal: The AAPS journal 20041201
Title: Mycobacterium xenopi pulmonary infection in two renal transplant recipients under sirolimus therapy.
Journal: Transplant infectious disease : an official journal of the Transplantation Society 20041201
Title: Mammalian target of rapamycin.
Journal: Seminars in oncology 20041201
Title: Mutagenic and cytotoxic effects of immunosuppressive drugs on human lymphocyte cultures.
Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20041201
Title: Nonuniform strut distribution correlates with more neointimal hyperplasia after sirolimus-eluting stent implantation.
Journal: Circulation 20041130
Title: Everolimus (Certican) 12-month safety and efficacy versus mycophenolate mofetil in de novo renal transplant recipients.
Journal: Transplantation 20041127
Title: Sirolimus may not cause neurotoxicity in kidney and liver transplant recipients.
Journal: Neurology 20041123
Title: Memory-like alterations in Aplysia axons after nerve injury or localized depolarization.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041117
Title: Comparison of late luminal loss response pattern after sirolimus-eluting stent implantation or conventional stenting.
Journal: Circulation 20041116
Title: Comparison of clinical and angiographic outcome of sirolimus-eluting stent implantation versus cutting balloon angioplasty for coronary in-stent restenosis.
Journal: The American journal of cardiology 20041115
Title: Targeted T-cell depletion or CD154 blockade generates mixed hemopoietic chimerism and donor-specific tolerance in mice treated with sirolimus and donor bone marrow.
Journal: Transplantation 20041115
Title: Early cyclosporine a withdrawal in kidney-transplant recipients receiving sirolimus prevents progression of chronic pathologic allograft lesions.
Journal: Transplantation 20041115
Title: Everolimus and reduced-exposure cyclosporine in de novo renal-transplant recipients: a three-year phase II, randomized, multicenter, open-label study.
Journal: Transplantation 20041115
Title: Investigation of pediatric renal transplant recipients with heavy proteinuria after sirolimus rescue.
Journal: Transplantation 20041115
Title: Construction of a cyclin D1-Cdk2 fusion protein to model the biological functions of cyclin D1-Cdk2 complexes.
Journal: The Journal of biological chemistry 20041112
Title: Autocrine transforming growth factor alpha regulates cell adhesion by multiple signaling via specific phosphorylation sites of p70S6 kinase in colon cancer cells.
Journal: The Journal of biological chemistry 20041105
Title: Tor signaling and nutrient-based signals converge on Mks1p phosphorylation to regulate expression of Rtg1.Rtg3p-dependent target genes.
Journal: The Journal of biological chemistry 20041105
Title: Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041103
Title: Phase I/pharmacokinetic study of CCI-779 in patients with recurrent malignant glioma on enzyme-inducing antiepileptic drugs.
Journal: Investigational new drugs 20041101
Title: The mTOR signaling pathway mediates control of ribosomal protein mRNA translation in rat liver.
Journal: The international journal of biochemistry & cell biology 20041101
Title: Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
Journal: Nature cell biology 20041101
Title: Cyclooxygenase-2 expression in experimental post-transplant obliterative bronchiolitis.
Journal: The Journal of pathology 20041101
Title: De novo kidney transplantation without use of calcineurin inhibitors preserves renal structure and function at two years.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041101
Title: Predictors of success in conversion from calcineurin inhibitor to sirolimus in chronic allograft dysfunction.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041101
Title: Initiation of mRNA translation in oncogenesis: the role of eIF4E.
Journal: Cell cycle (Georgetown, Tex.) 20041101
Title: Targeting metastatic leiomyosarcoma by rapamycin plus gemcitabine: an intriguing clinical observation.
Journal: International journal of molecular medicine 20041101
Title: Sirolimus and angiotensin-converting enzyme inhibitors together induce tongue oedema in renal transplant recipients.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041101
Title: Sirolimus-induced pneumonitis, sinusitis and macular oedema.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041101
Title: Sirolimus- or paclitaxel-eluting stents to prevent coronary artery restenosis.
Journal: Expert opinion on pharmacotherapy 20041101
Title: Vascular restenosis - striving for therapy.
Journal: Expert opinion on pharmacotherapy 20041101
Title: Drug-eluting stents have made brachytherapy obsolete.
Journal: Current opinion in cardiology 20041101
Title: Selectin inhibitor bimosiamose prolongs survival of kidney allografts by reduction in intragraft production of cytokines and chemokines.
Journal: Journal of the American Society of Nephrology : JASN 20041101
Title: regulation of peroxisome proliferator-activated receptor-gamma activity by mammalian target of rapamycin and amino acids in adipogenesis.
Journal: Diabetes 20041101
Title: Bcl-2 and CCND1/CDK4 expression levels predict the cellular effects of mTOR inhibitors in human ovarian carcinoma.
Journal: Apoptosis : an international journal on programmed cell death 20041101
Title: Sirolimus-eluting stents for the prevention of restenosis in a worst-case scenario of diffuse and recurrent in-stent restenosis.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20041101
Title: Drug-eluting stents for secondary prevention of restenosis.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20041101
Title: Hybrid coronary revascularization in the era of drug-eluting stents.
Journal: The Annals of thoracic surgery 20041101
Title: Rapamycin-eluting stents for the treatment of bifurcated coronary lesions: a randomized comparison of a simple versus complex strategy.
Journal: American heart journal 20041101
Title: Drug-eluting stents: a mechanical and pharmacologic approach to coronary artery disease.
Journal: Pharmacotherapy 20041101
Title: Everolimus suppresses cancellous bone loss, bone resorption, and cathepsin K expression by osteoclasts.
Journal: Bone 20041101
Title: Combining targeted agents in lung cancer.
Journal: Clinical lung cancer 20041101
Title: [Consensus-recommendations for sirolimus in liver transplantation].
Journal: Zeitschrift fur Gastroenterologie 20041101
Title: Sirolimus addition is beneficial for renal allograft dysfunction due to simultaneous acute rejection episode and calcineurin inhibitor nephrotoxicity.
Journal: Transplantation proceedings 20041101
Title: Combined use of sirolimus and voriconazole in renal transplantation: a report of two cases.
Journal: Transplantation proceedings 20041101
Title: Targeting the molecular target of rapamycin (mTOR).
Journal: Current opinion in oncology 20041101
Title: Bibliography. Current world literature. Therapeutic modalities.
Journal: Current opinion in oncology 20041101
Title: Molecular cross-talk between MEK1/2 and mTOR signaling during recovery of 293 cells from hypertonic stress.
Journal: The Journal of biological chemistry 20041029
Title: Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1alpha, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling.
Journal: The Journal of biological chemistry 20041029
Title: Immunomodulatory effects of combination of pooled human gammaglobulin and rapamycin on cell proliferation and apoptosis in the mixed lymphocyte reaction.
Journal: Transplantation 20041027
Title: Sirolimus in de novo heart transplant recipients reduces acute rejection and prevents coronary artery disease at 2 years: a randomized clinical trial.
Journal: Circulation 20041026
Title: Targeting the mammalian target of rapamycin (mTOR): a new approach to treating cancer.
Journal: British journal of cancer 20041018
Title: Rapamycin causes activation of protein phosphatase-2A1 and nuclear translocation of PCNA in CD4+ T cells.
Journal: Biochemical and biophysical research communications 20041015
Title: Rapamycin inhibits proliferation and differentiation of human endothelial progenitor cells in vitro.
Journal: Experimental cell research 20041015
Title: Bivalirudin versus heparin as an antithrombotic agent in patients treated with a sirolimus-eluting stent.
Journal: The American journal of cardiology 20041015
Title: BK virus-associated nephropathy in renal allograft recipients: rescue therapy by sirolimus-based immunosuppression.
Journal: Transplantation 20041015
Title: Putting the rap on Akt.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041015
Title: Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041015
Title: Effect of rapamycin alone and in combination with antiangiogenesis therapy in an orthotopic model of human pancreatic cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041015
Title: Targeting mammalian target of rapamycin synergistically enhances chemotherapy-induced cytotoxicity in breast cancer cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041015
Title: Problems with drug-eluting coronary stents--the FDA perspective.
Journal: The New England journal of medicine 20041014
Title: Receptor activity-independent recruitment of betaarrestin2 reveals specific signalling modes.
Journal: The EMBO journal 20041013
Title: In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids.
Journal: The Journal of biological chemistry 20041008
Title: Oral rapamycin to inhibit restenosis after stenting of de novo coronary lesions: the Oral Rapamune to Inhibit Restenosis (ORBIT) study.
Journal: Journal of the American College of Cardiology 20041006
Title: Evaluation of a cyano stationary phase for the determination of tacrolimus, sirolimus and cyclosporin A in whole blood by high-performance liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041005
Title: Activation of an autoregulated protein kinase by conditional protein splicing.
Journal: Angewandte Chemie (International ed. in English) 20041004
Title: Directing flux in glycan biosynthetic pathways with a small molecule switch.
Journal: Chembiochem : a European journal of chemical biology 20041004
Title: Human placental taurine transporter in uncomplicated and IUGR pregnancies: cellular localization, protein expression, and regulation.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20041001
Title: Simple extraction protocol for analysis of immunosuppressant drugs in whole blood.
Journal: Clinical chemistry 20041001
Title: Tolerability and steady-state pharmacokinetics of everolimus in maintenance renal transplant patients.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041001
Title: Sirolimus-associated hepatotoxicity in liver transplantation.
Journal: The Annals of pharmacotherapy 20041001
Title: Alterations in glucose metabolism by cyclosporine in rat brain slices link to oxidative stress: interactions with mTOR inhibitors.
Journal: British journal of pharmacology 20041001
Title: Effect of sirolimus withdrawal in patients with deteriorating renal function.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041001
Title: What is the calcineurin inhibitor of choice for pediatric renal transplantation?
Journal: Pediatric transplantation 20041001
Title: Current immunosuppressive agents in pediatric renal transplantation: efficacy, side-effects and utilization.
Journal: Pediatric transplantation 20041001
Title: Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20041001
Title: Echolucent neointimal hyperplasia 'dark wall' after sirolimus eluting stent implantation.
Journal: Heart (British Cardiac Society) 20041001
Title: Routine sirolimus eluting stent implantation for unselected in-stent restenosis: insights from the rapamycin eluting stent evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry.
Journal: Heart (British Cardiac Society) 20041001
Title: Mammalian target of rapamycin and 3-phosphatidylinositol 3-kinase pathway inhibition enhances growth inhibition of transforming growth factor-beta1 in prostate cancer cells.
Journal: The Journal of urology 20041001
Title: Sirolimus-based immunosuppression for liver transplantation in the presence of extended criteria for hepatocellular carcinoma.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20041001
Title: Hepatocellular cancer, transplantation, and sirolimus.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20041001
Title: [Sirolimus-eluting stents for the treatment of symptomatic extracranial vertebral artery stenoses: early experience and 6-month follow-up].
Journal: RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 20041001
Title: New insights into drug absorption: studies with sirolimus.
Journal: Therapeutic drug monitoring 20041001
Title: Everolimus therapeutic concentration range defined from a prospective trial with reduced-exposure cyclosporine in de novo kidney transplantation.
Journal: Therapeutic drug monitoring 20041001
Title: Raptor protein contains a caspase-like domain.
Journal: Trends in biochemical sciences 20041001
Title: Human cytomegalovirus infection induces rapamycin-insensitive phosphorylation of downstream effectors of mTOR kinase.
Journal: Journal of virology 20041001
Title: Effectiveness of sirolimus-eluting stent implantation for the treatment of coronary artery disease in octogenarians.
Journal: The American journal of cardiology 20041001
Title: Comparison of acute and long-term results and underlying mechanisms from sirolimus-eluting stent implantation for the treatment of in-stent restenosis and recurrent in-stent restenosis in patients in whom intracoronary radiation failed as assessed by intravascular ultrasound.
Journal: The American journal of cardiology 20041001
Title: Ischemia-reperfusion induces glomerular and tubular activation of proinflammatory and antiapoptotic pathways: differential modulation by rapamycin.
Journal: Journal of the American Society of Nephrology : JASN 20041001
Title: PP2A phosphatase activity is required for stress and Tor kinase regulation of yeast stress response factor Msn2p.
Journal: Eukaryotic cell 20041001
Title: Pharmacokinetics of rapamycin-eluting stents in miniswine coronary model.
Journal: Chinese medical journal 20041001
Title: Drug-eluting stents: some bare facts.
Journal: Lancet (London, England) 20041001
Title: Late thrombosis in drug-eluting coronary stents after discontinuation of antiplatelet therapy.
Journal: Lancet (London, England) 20041001
Title: Drug-eluting stents: from randomized trials to the real world.
Journal: Minerva cardioangiologica 20041001
Title: Coronary bifurcation stenting. Current techniques, outcome and possible future developments.
Journal: Minerva cardioangiologica 20041001
Title: Saphenous vein graft disease.
Journal: Minerva cardioangiologica 20041001
Title: Drug-eluting stents: the beginning of the end of restenosis?
Journal: Cleveland Clinic journal of medicine 20041001
Title: [Drug eluting stents--end of restenosis?].
Journal: Vnitrni lekarstvi 20041001
Title: [Immunossupresive drugs in renal transplantation].
Journal: Polskie Archiwum Medycyny Wewnetrznej 20041001
Title: Medical devices; clinical chemistry and clinical toxicology devices; classification of sirolimus test system devices. Final rule.
Journal: Federal register 20040930
Title: Akt-1 expression level regulates CNS precursors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040929
Title: Active role of chimerism in transplantation tolerance induced by antilymphocyte serum, sirolimus, and bone-marrow-cell infusion.
Journal: Transplantation 20040927
Title: The selective use of basiliximab versus thymoglobulin in combination with sirolimus for cadaveric renal transplant recipients at low risk versus high risk for delayed graft function.
Journal: Transplantation 20040927
Title: Correlation between human leukocyte antigen antibody production and serum creatinine in patients receiving sirolimus monotherapy after Campath-1H induction.
Journal: Transplantation 20040927
Title: Sirolimus-induced interstitial pneumonitis after renal transplantation.
Journal: Transplantation 20040927
Title: Mammalian target of rapamycin inhibition as therapy for hematologic malignancies.
Journal: Cancer 20040915
Title: Late coronary thrombosis secondary to a sirolimus-eluting stent.
Journal: Circulation 20040914
Title: Uth1p is involved in the autophagic degradation of mitochondria.
Journal: The Journal of biological chemistry 20040910
Title: Progressive changes in Met-dependent signaling in a human ovarian surface epithelial model of malignant transformation.
Journal: Experimental cell research 20040910
Title: NPR1 kinase and RSP5-BUL1/2 ubiquitin ligase control GLN3-dependent transcription in Saccharomyces cerevisiae.
Journal: The Journal of biological chemistry 20040903
Title: Regulation of adipocyte differentiation and insulin action with rapamycin.
Journal: Biochemical and biophysical research communications 20040903
Title: Both mitogen-activated protein kinase and phosphatidylinositol 3-kinase signalling are required in epidermal growth factor-induced human trophoblast migration.
Journal: Molecular human reproduction 20040901
Title: Sirolimus for GVHD prophylaxis in allogeneic stem cell transplantation.
Journal: Bone marrow transplantation 20040901
Title: Trace analysis of rapamycin in human blood by micellar electrokinetic chromatography.
Journal: Analytical and bioanalytical chemistry 20040901
Title: The Cypher stent: no longer efficacious at three months in the porcine model?
Journal: Cardiovascular research 20040901
Title: Long-term effects of polymer-based, slow-release, sirolimus-eluting stents in a porcine coronary model.
Journal: Cardiovascular research 20040901
Title: CYP3A4 and P-glycoprotein activity in healthy controls and transplant patients on cyclosporin vs. tacrolimus vs. sirolimus.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040901
Title: Sirolimus-induced leukocytoclastic vasculitis: the second case reported.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040901
Title: The use of drug eluting stents in single and multivessel disease: results from a single centre experience.
Journal: Heart (British Cardiac Society) 20040901
Title: Sirolimus eluting stent implantation for patients with multivessel disease: rationale for the Arterial Revascularisation Therapies Study part II (ARTS II).
Journal: Heart (British Cardiac Society) 20040901
Title: Prevention of restenosis after coronary angioplasty.
Journal: Current opinion in cardiology 20040901
Title: ANG II activates effectors of mTOR via PI3-K signaling in human coronary smooth muscle cells.
Journal: American journal of physiology. Heart and circulatory physiology 20040901
Title: Synovial fibroblasts from patients with rheumatoid arthritis, like fibroblasts from Graves' disease, express high levels of IL-16 when treated with Igs against insulin-like growth factor-1 receptor.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040901
Title: Preservation of graft function in low-risk living kidney transplant recipients treated with a combination of sirolimus and cyclosporine.
Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040901
Title: Clinical and angiographic outcome after sirolimus-eluting stent implantation in aorto-ostial lesions.
Journal: Journal of the American College of Cardiology 20040901
Title: Type D personality predicts death or myocardial infarction after bare metal stent or sirolimus-eluting stent implantation: a Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry substudy.
Journal: Journal of the American College of Cardiology 20040901
Title: Effect of sirolimus on renal ischaemia/reperfusion injury in normotensive and hypertensive rats.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20040901
Title: Role of siroliumus, a novel immunosuppressive drug in heart and lung transplantation.
Journal: Respiratory medicine 20040901
Title: 5-HT stimulates eEF2 dephosphorylation in a rapamycin-sensitive manner in Aplysia neurites.
Journal: Journal of neurochemistry 20040901
Title: Elective sirolimus-eluting stent implantation for multivessel disease involving significant LAD stenosis: one-year clinical outcomes of 99 consecutive patients--the Rotterdam experience.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040901
Title: Single-digit target vessel revascularization in multivessel coronary interventions with sirolimus-eluting stents: goodbye to coronary bypass grafting.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040901
Title: Bifurcation disease: optimal angiographic result yet suboptimal long-term outcome.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040901
Title: Drug-eluting stents: caution and concerns for long-term outcome.
Journal: Coronary artery disease 20040901
Title: Rapamycin-sensitive induction of eukaryotic initiation factor 4F in regenerating mouse liver.
Journal: Hepatology (Baltimore, Md.) 20040901
Title: Prolyl isomerases in yeast.
Journal: Frontiers in bioscience : a journal and virtual library 20040901
Title: Difficulty in establishing sirolimus therapy as a cause of interstitial pneumonitis in renal-transplant recipients.
Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20040901
Title: [Drug-coated stents. Where do we stand in 2004?].
Journal: Zeitschrift fur Kardiologie 20040901
Title: [When are drug-eluting stents effective? A critical analysis of the presently available data].
Journal: Zeitschrift fur Kardiologie 20040901
Title: Drug-eluting stents: is it the beginning of the end for coronary artery bypass surgery?
Journal: Chinese medical journal 20040901
Title: Rapamycin-eluting stents for the treatment of unprotected left main coronary disease.
Journal: American heart journal 20040901
Title: Current and future immunosuppressive strategies in renal transplantation.
Journal: Pharmacotherapy 20040901
Title: Sirolimus (rapamycin) reduces the incidence of acute rejection episodes in renal transplantation: an initial experience in Taiwan.
Journal: Transplantation proceedings 20040901
Title: Sirolimus in chronic allograft nephropathy.
Journal: Transplantation proceedings 20040901
Title: Is sirolimus a safe alternative to reduce or eliminate calcineurin inhibitors in chronic allograft nephropathy in kidney transplantation?
Journal: Transplantation proceedings 20040901
Title: Pharmacokinetic variability of sirolimus in Taiwanese renal transplant recipients.
Journal: Transplantation proceedings 20040901
Title: Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity.
Journal: The Journal of biological chemistry 20040827
Title: Long-term outcome of sirolimus rescue in kidney-pancreas transplantation.
Journal: Transplantation 20040827
Title: Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways.
Journal: Circulation research 20040820
Title: [PTCA with drug eluting stent. 90% fewer restenoses in high risk patients].
Journal: MMW Fortschritte der Medizin 20040819
Title: Randomized, double-blind, placebo-controlled trial of oral sirolimus for restenosis prevention in patients with in-stent restenosis: the Oral Sirolimus to Inhibit Recurrent In-stent Stenosis (OSIRIS) trial.
Journal: Circulation 20040817
Title: Rapid simultaneous quantification of immunosuppressants in transplant patients by turbulent flow chromatography combined with tandem mass spectrometry.
Journal: Clinica chimica acta; international journal of clinical chemistry 20040816
Title: Ras, PI3-kinase and mTOR signaling in cardiac hypertrophy.
Journal: Cardiovascular research 20040815
Title: Acute nephrotoxicity of tacrolimus and sirolimus in renal isografts: differential intragraft expression of transforming growth factor-beta1 and alpha-smooth muscle actin.
Journal: Transplantation 20040815
Title: Differential effects of everolimus and cyclosporine A on intimal alpha-actin-positive cell dynamics of carotid allografts in mice.
Journal: Transplantation 20040815
Title: Comparison of outcomes after delayed graft function: sirolimus-based versus other calcineurin-inhibitor sparing induction immunosuppression regimens.
Journal: Transplantation 20040815
Title: [Immunosuppression with sirolimus so donor kidneys survive longer].
Journal: MMW Fortschritte der Medizin 20040805
Title: Cost-effectiveness of sirolimus-eluting stents for treatment of complex coronary stenoses: results from the Sirolimus-Eluting Balloon Expandable Stent in the Treatment of Patients With De Novo Native Coronary Artery Lesions (SIRIUS) trial.
Journal: Circulation 20040803
Title: Economics of sirolimus-eluting stents: drug-eluting stents have really arrived.
Journal: Circulation 20040803
Title: Marked malapposition and aneurysm formation after sirolimus-eluting coronary stent implantation.
Journal: Circulation 20040803
Title: G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells.
Journal: American journal of physiology. Cell physiology 20040801
Title: Two-year incidence of malignancy in sirolimus-treated renal transplant recipients: results from five multicenter studies.
Journal: Clinical transplantation 20040801
Title: Cross-talk between the survival kinases during early reperfusion: its contribution to ischemic preconditioning.
Journal: Cardiovascular research 20040801
Title: Late incomplete lesion coverage following Cypher stent deployment for diffuse right coronary artery stenosis.
Journal: Heart (British Cardiac Society) 20040801
Title: Using established immunosuppressant therapy effectively: lessons from the measurement of mycophenolic acid plasma concentrations.
Journal: Therapeutic drug monitoring 20040801
Title: Improvement in renal function and rejection control in pediatric liver transplant recipients with the introduction of sirolimus.
Journal: Pediatric transplantation 20040801
Title: Pilot randomized study of early tacrolimus withdrawal from a regimen with sirolimus plus tacrolimus in kidney transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040801
Title: Therapeutic drug monitoring of sirolimus: effect of concomitant immunosuppressive therapy and optimization of drug dosing.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040801
Title: Effectiveness of sirolimus-eluting stent implantation for treatment of in-stent restenosis after brachytherapy failure.
Journal: The American journal of cardiology 20040801
Title: The current status of stent placement in small coronary arteries < 3.0 mm in diameter.
Journal: The Journal of invasive cardiology 20040801
Title: Contemporary treatment of small-vessel disease.
Journal: The Journal of invasive cardiology 20040801
Title: Rapamycin-mediated induction of gamma-globin mRNA accumulation in human erythroid cells.
Journal: British journal of haematology 20040801
Title: Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway.
Journal: Developmental cell 20040801
Title: Rapamycin suppresses experimental aortic aneurysm growth.
Journal: Journal of vascular surgery 20040801
Title: Aortic eNOS expression and phosphorylation in Apo-E knockout mice: differing effects of rapamycin and simvastatin.
Journal: Surgery 20040801
Title: Oral rapamycin to prevent human coronary stent restenosis: a pilot study.
Journal: American heart journal 20040801
Title: Are drug-eluting stents a panacea for patients with coronary heart disease?
Journal: Lancet (London, England) 20040801
Title: A hierarchical Bayesian meta-analysis of randomised clinical trials of drug-eluting stents.
Journal: Lancet (London, England) 20040801
Title: Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte.
Journal: The Journal of biological chemistry 20040730
Title: Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt.
Journal: Oncogene 20040729
Title: AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth.
Journal: Oncogene 20040729
Title: Treatment of left anterior descending coronary artery disease with sirolimus-eluting stents.
Journal: Circulation 20040727
Title: Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton.
Journal: Current biology : CB 20040727
Title: A retrospective review of liver transplant patients treated with sirolimus from a single center: an analysis of sirolimus-related complications.
Journal: Transplantation 20040727
Title: Everolimus-induced drug fever after heart transplantation.
Journal: Transplantation 20040727
Title: Evidence for cyclin D3 as a novel target of rapamycin in human T lymphocytes.
Journal: The Journal of biological chemistry 20040723
Title: In vitro study of release mechanisms of paclitaxel and rapamycin from drug-incorporated biodegradable stent matrices.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20040723
Title: An activated mTOR mutant supports growth factor-independent, nutrient-dependent cell survival.
Journal: Oncogene 20040722
Title: Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent.
Journal: The Journal of biological chemistry 20040716
Title: Aldosterone rapidly activates Src kinase in M-1 cells involving the mineralocorticoid receptor and HSP84.
Journal: FEBS letters 20040716
Title: Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040714
Title: Images in cardiovascular medicine. Vascular healing 4 years after the implantation of sirolimus-eluting stent in humans: a histopathological examination.
Journal: Circulation 20040706
Title: Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus.
Journal: The Journal of biological chemistry 20040702
Title: Association of rapamycin and co-stimulation blockade using anti-B7 antibodies in renal allotransplantation in baboons.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040701
Title: Reversing drug resistance in vivo.
Journal: Cell cycle (Georgetown, Tex.) 20040701
Title: Biological aspects of radiation and drug-eluting stents for the prevention of restenosis.
Journal: Cardiovascular research 20040701
Title: Sirolimus impairs gonadal function in heart transplant recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040701
Title: Successful simultaneous islet-kidney transplantation using a steroid-free immunosuppression: two-year follow-up.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040701
Title: Different costimulatory and growth factor requirements for CD4+ and CD8+ T cell-mediated rejection.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040701
Title: Differential expression of chemokines and chemokine receptors in murine islet allografts: the role of CCR2 and CCR5 signaling pathways.
Journal: Journal of the American Society of Nephrology : JASN 20040701
Title: Effectiveness of sirolimus-Eluting stent implantation for coronary narrowings <50% in diameter.
Journal: The American journal of cardiology 20040701
Title: Restenosis rates following bifurcation stenting with sirolimus-eluting stents for de novo narrowings.
Journal: The American journal of cardiology 20040701
Title: Drug-eluting stents: the panacea for restenosis?
Journal: Singapore medical journal 20040701
Title: A stent is not just a stent: Stent construction and design do matter in its clinical performance.
Journal: Singapore medical journal 20040701
Title: Clinical outcomes for sirolimus-eluting stent implantation and vascular brachytherapy for the treatment of in-stent restenosis.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040701
Title: 'At least but not at last' equivalent!
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040701
Title: Vascular brachytherapy vs. drug-eluting stents for the treatment of in-stent restenosis: the jury's still out.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040701
Title: Elective sirolimus-eluting stent implantation for left main coronary artery disease: six-month angiographic follow-up and 1-year clinical outcome.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040701
Title: Immunosuppression and modulation in liver transplantation.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040701
Title: Rapamycin and chronic lung rejection.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040701
Title: [Antiproliferative drug-eluting stents: systematic review of the benefits and estimate of economic impact].
Journal: Revista espanola de cardiologia 20040701
Title: Drug-eluting stents: the end of restenosis?
Journal: Annals of the Academy of Medicine, Singapore 20040701
Title: [Inhibition of hypoxia-inducible factor 1alpha expression and tumor growth in SKOV3 ovarian cancer model by sirolimus].
Journal: Zhonghua fu chan ke za zhi 20040701
Title: The mTOR/p70S6K signal transduction pathway plays a role in cardiac hypertrophy and influences expression of myosin heavy chain genes in vivo.
Journal: Cardiovascular drugs and therapy 20040701
Title: Isolation, structure determination and biological activity of 15-deoxo-7,32-O-didesmethylrapamycin from the soil actinomycete LL-D45042.
Journal: The Journal of antibiotics 20040701
Title: Pro- and anti-cancer effects of immunosuppressive agents used in organ transplantation.
Journal: Transplantation 20040627
Title: Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload.
Journal: Circulation 20040622
Title: Regulation of translation elongation and phosphorylation of eEF2 in rat pancreatic acini.
Journal: Biochemical and biophysical research communications 20040618
Title: Mechanical stimuli regulate rapamycin-sensitive signalling by a phosphoinositide 3-kinase-, protein kinase B- and growth factor-independent mechanism.
Journal: The Biochemical journal 20040615
Title: New target, new drug, old paradigm.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040615
Title: Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040615
Title: Angiographic and volumetric intravascular ultrasound comparison between direct sirolimus-eluting stent implantation versus predilation.
Journal: The American journal of cardiology 20040615
Title: Stable expression of small interfering RNA sensitizes TEL-PDGFbetaR to inhibition with imatinib or rapamycin.
Journal: The Journal of clinical investigation 20040615
Title: New immunosuppressant class not without serious concerns.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040615
Title: Intraprocedural stent thrombosis during implantation of sirolimus-eluting stents.
Journal: Circulation 20040608
Title: 96-Well liquid-liquid extraction liquid chromatography-tandem mass spectrometry method for the quantitative determination of ABT-578 in human blood samples.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040605
Title: Interferon alpha-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target of rapamycin signaling pathway.
Journal: The Journal of biological chemistry 20040604
Title: Degradation of PKB/Akt protein by inhibition of the VEGF receptor/mTOR pathway in endothelial cells.
Journal: Oncogene 20040603
Title: Significant reduction in restenosis after the use of sirolimus-eluting stents in the treatment of chronic total occlusions.
Journal: Journal of the American College of Cardiology 20040602
Title: Impact of final stent dimensions on long-term results following sirolimus-eluting stent implantation: serial intravascular ultrasound analysis from the sirius trial.
Journal: Journal of the American College of Cardiology 20040602
Title: Rab7 is required for the normal progression of the autophagic pathway in mammalian cells.
Journal: Journal of cell science 20040601
Title: Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.
Journal: Nature genetics 20040601
Title: Increased risk of thrombotic microangiopathy in patients receiving a cyclosporin-sirolimus combination.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040601
Title: Sirolimus-based therapy following early cyclosporine withdrawal provides significantly improved renal histology and function at 3 years.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040601
Title: Outcome at 3 years with a prednisone-free maintenance regimen: a single-center experience with 349 kidney transplant recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040601
Title: Sirolimus-induced angioedema.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040601
Title: Post-sirolimus-eluting stent restenosis treated with repeat percutaneous intervention: late angiographic and clinical outcomes.
Journal: Circulation 20040601
Title: mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.
Journal: Nature medicine 20040601
Title: HIV infection of primary human T cells is determined by tunable thresholds of T cell activation.
Journal: European journal of immunology 20040601
Title: Sirolimus- versus paclitaxel-eluting stents in patients with stenosis in a native coronary artery.
Journal: Expert opinion on pharmacotherapy 20040601
Title: Creatine kinase-myocardial band isoenzyme elevation after percutaneous coronary interventions using sirolimus-eluting stents.
Journal: The American journal of cardiology 20040601
Title: TORward AKTually useful mouse models.
Journal: Nature medicine 20040601
Title: Sirolimus for pediatric liver transplant recipients with post-transplant lymphoproliferative disease and hepatoblastoma.
Journal: Pediatric transplantation 20040601
Title: Immunosuppressive drug monitoring of sirolimus and cyclosporine in pediatric patients.
Journal: Clinical biochemistry 20040601
Title: First experience with rapamycin-based immunosuppression to improve kidney function after heart transplantation.
Journal: The Thoracic and cardiovascular surgeon 20040601
Title: The impact of Sirolimus Eluting stents in interventional cardiology.
Journal: International journal of cardiology 20040601
Title: Procedural and long-term results of sirolimus-eluting stent in patients at high risk for restenosis.
Journal: Minerva cardioangiologica 20040601
Title: Pharmacokinetics of sirolimus in heart transplant recipients with chronic renal impairment.
Journal: Transplantation proceedings 20040601
Title: Chronic allograft nephropathy: pathogenesis and management of an important posttransplant complication.
Journal: Progress in transplantation (Aliso Viejo, Calif.) 20040601
Title: Future immunosuppressive agents in solid-organ transplantation.
Journal: Progress in transplantation (Aliso Viejo, Calif.) 20040601
Title: Strategies to prevent chronic allograft nephropathy in kidney transplantation: focus on calcineurin inhibitors.
Journal: Progress in transplantation (Aliso Viejo, Calif.) 20040601
Title: The efficacy and limitations of sirolimus conversion in liver transplant patients who develop renal dysfunction on calcineurin inhibitors.
Journal: Digestive diseases and sciences 20040601
Title: Eluting stents: an effective, promising solution?
Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20040601
Title: Sirolimus and mycophenolate mofetil as calcineurin inhibitor-free immunosuppression in a cardiac transplant patient with chronic renal failure.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040601
Title: Fatal interstitial pneumonitis associated with sirolimus therapy in a heart transplant recipient.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040601
Title: [Involvement of hnRNP in selective translation inhibition of mRNA by rapamycin].
Journal: The Japanese journal of antibiotics 20040601
Title: [Effect of EM201, an in vivo metabolite of erythromycin (EM), on signal transduction of IL-2 receptor].
Journal: The Japanese journal of antibiotics 20040601
Title: Dimerization is required for activation of eIF2 kinase Gcn2 in response to diverse environmental stress conditions.
Journal: The Journal of biological chemistry 20040528
Title: Mammalian target of rapamycin positively regulates collagen type I production via a phosphatidylinositol 3-kinase-independent pathway.
Journal: The Journal of biological chemistry 20040528
Title: Metabolic interaction between cyclosporine and sirolimus.
Journal: Transplantation 20040527
Title: Wound-healing complications after kidney transplantation: a prospective, randomized comparison of sirolimus and tacrolimus.
Journal: Transplantation 20040527
Title: Impact of sirolimus-eluting stents on outcome in diabetic patients: a SIRIUS (SIRolImUS-coated Bx Velocity balloon-expandable stent in the treatment of patients with de novo coronary artery lesions) substudy.
Journal: Circulation 20040518
Title: Incidence of thrombotic stent occlusion during the first three months after sirolimus-eluting stent implantation in 500 consecutive patients.
Journal: The American journal of cardiology 20040515
Title: Perturbed IFN-gamma-Jak-signal transducers and activators of transcription signaling in tuberous sclerosis mouse models: synergistic effects of rapamycin-IFN-gamma treatment.
Journal: Cancer research 20040515
Title: Rapamycin protects allografts from rejection while simultaneously attacking tumors in immunosuppressed mice.
Journal: Transplantation 20040515
Title: An update on clinical outcomes in heart and lung transplantation.
Journal: Transplantation 20040515
Title: Involvement of integrins and Src in insulin signaling toward autophagic proteolysis in rat liver.
Journal: The Journal of biological chemistry 20040514
Title: Critical role of T-loop and H-motif phosphorylation in the regulation of S6 kinase 1 by the tuberous sclerosis complex.
Journal: The Journal of biological chemistry 20040514
Title: Essential role of PDGFRalpha-p70S6K signaling in mesenchymal cells during therapeutic and tumor angiogenesis in vivo: role of PDGFRalpha during angiogenesis.
Journal: Circulation research 20040514
Title: 'Me-too' products--friend or foe?
Journal: The New England journal of medicine 20040513
Title: Six- and twelve-month results from first human experience using everolimus-eluting stents with bioabsorbable polymer.
Journal: Circulation 20040511
Title: How many grails do we need?
Journal: Circulation 20040511
Title: Everolimus stent proves effective.
Journal: Circulation 20040511
Title: Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals.
Journal: The Journal of biological chemistry 20040507
Title: Images in cardiovascular medicine. Coronary uptake of gallium-67 citrate after implantation of sirolimus-eluting stent.
Journal: Circulation 20040504
Title: Isolation and characterization of pre-rapamycin, the first macrocyclic intermediate in the biosynthesis of the immunosuppressant rapamycin by S. hygroscopicus.
Journal: Angewandte Chemie (International ed. in English) 20040503
Title: Early experiences and clinical implications of restenosis and drug-eluting stents: Part 2.
Journal: The Annals of pharmacotherapy 20040501
Title: Pharmacokinetics of sirolimus and tacrolimus in pediatric transplant patients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040501
Title: Sirolimus eluting stent aborted recurrent distal left main in-stent restenosis involving bifurcation.
Journal: Heart (British Cardiac Society) 20040501
Title: Optimizing the immunosuppressive regimen in heart transplantation.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040501
Title: Effectiveness of the sirolimus-eluting stent in the treatment of patients with a prior history of coronary artery bypass graft surgery.
Journal: Coronary artery disease 20040501
Title: Acute rapamycin nephrotoxicity in native kidneys of patients with chronic glomerulopathies.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040501
Title: Use of sirolimus-eluting coronary stents in routine clinical practice.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040501
Title: Day in and day out.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040501
Title: Economic evaluation of everolimus versus mycophenolate mofetil in combination with cyclosporine and prednisolone in de novo renal transplant recipients.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20040501
Title: Local application of rapamycin inhibits neointimal hyperplasia in experimental vein grafts.
Journal: The Annals of thoracic surgery 20040501
Title: Sirolimus and tacrolimus without methotrexate as graft-versus-host disease prophylaxis after matched related donor peripheral blood stem cell transplantation.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20040501
Title: Rapamycin-associated post-transplantation glomerulonephritis and its remission after reintroduction of calcineurin-inhibitor therapy.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20040501
Title: Sirolimus-induced hyperlipidaemia in liver transplant recipients is not dose-dependent.
Journal: Alimentary pharmacology & therapeutics 20040501
Title: The TOR pathway: a target for cancer therapy.
Journal: Nature reviews. Cancer 20040501
Title: Clinical impact of stent construction and design in percutaneous coronary intervention.
Journal: American heart journal 20040501
Title: Airway anastomosis complications in de novo lung transplantation with sirolimus-based immunosuppression.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040501
Title: [Active stents: towards total prevention of restenosis?].
Journal: Pathologie-biologie 20040501
Title: Effectiveness of the sirolimus-eluting stent in the treatment of saphenous vein graft disease.
Journal: The Journal of invasive cardiology 20040501
Title: Drug-eluting stents and saphenous vein graft intervention.
Journal: The Journal of invasive cardiology 20040501
Title: Rapamycin inhibits release of tumor necrosis factor-alpha from human vascular smooth muscle cells.
Journal: The American surgeon 20040501
Title: Chemical dimerizers and three-hybrid systems: scanning the proteome for targets of organic small molecules.
Journal: Chemistry & biology 20040501
Title: Selective modulation of some forms of schaffer collateral-CA1 synaptic plasticity in mice with a disruption of the CPEB-1 gene.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20040501
Title: Sirolimus-eluting stent implantation in a heart transplant recipient.
Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20040501
Title: Rapamycin even when combined with cyclosporine attenuates tumor growth but does not induce regression of established walker sarcomas.
Journal: Transplantation proceedings 20040501
Title: Immunosuppression in pancreas transplantation: mycophenolate mofetil versus sirolimus.
Journal: Transplantation proceedings 20040501
Title: Long-term outcome of sirolimus rescue in kidney-pancreas transplantation.
Journal: Transplantation proceedings 20040501
Title: Islet of Langerhans allogeneic transplantation at the University of Geneva in the steroid free era in islet after kidney and simultaneous islet-kidney transplantations.
Journal: Transplantation proceedings 20040501
Title: Glucose-induced binding of the polypyrimidine tract-binding protein (PTB) to the 3'-untranslated region of the insulin mRNA (ins-PRS) is inhibited by rapamycin.
Journal: Molecular and cellular biochemistry 20040501
Title: High-dose bolus tirofiban and sirolimus eluting stent versus abiciximab and bare metal stent in acute myocardial infarction (STRATEGY) study--protocol design and demography of the first 100 patients.
Journal: Cardiovascular drugs and therapy 20040501
Title: [From sirolimus to the Cypher stent: stages of the victory against restenosis].
Journal: Annales de cardiologie et d'angeiologie 20040501
Title: [Sirolimus endoprosthesis: data from the RAVEL and the SIRIUS study].
Journal: Annales de cardiologie et d'angeiologie 20040501
Title: [The E-SIRIUS and the new SIRIUS clinical trials].
Journal: Annales de cardiologie et d'angeiologie 20040501
Title: [The e-Cypher registry: objectives and organization].
Journal: Annales de cardiologie et d'angeiologie 20040501
Title: [The national registry EVASTENT: cost-effectiveness analysis of the sirolimus active stent in diabetic and non-diabetic patients].
Journal: Annales de cardiologie et d'angeiologie 20040501
Title: [BRIDGE registry (safety and efficacy registry Bx Cyper stent in the RevascularIzation of patients with siGnificative risk of rEstenosis): protocol description and preliminary results].
Journal: Annales de cardiologie et d'angeiologie 20040501
Title: [Sirolimus-releasing coronary stent: lessons from the Rotterdam experience].
Journal: Annales de cardiologie et d'angeiologie 20040501
Title: [Cypher stent: the German registry. Results of the German prospective multicenter registry on Cypher].
Journal: Annales de cardiologie et d'angeiologie 20040501
Title: [The Cypher stent: most recent news of the 2004 Congress of the American College of Cardiology].
Journal: Annales de cardiologie et d'angeiologie 20040501
Title: [Cypher: ongoing studies].
Journal: Annales de cardiologie et d'angeiologie 20040501
Title: [The Siro-ISR registry: treatment of intra-stent restenosis with the sirolimus stent in the real world].
Journal: Annales de cardiologie et d'angeiologie 20040501
Title: [Cypher stent: upcoming clinical studies].
Journal: Annales de cardiologie et d'angeiologie 20040501
Title: ['Active' endoprosthesis with in situ release of an antimitotic or cytostatic drug: a revolution that cannot do without thought].
Journal: Annales de cardiologie et d'angeiologie 20040501
Title: Actin cytoskeleton is required for nuclear accumulation of Gln3 in response to nitrogen limitation but not rapamycin treatment in Saccharomyces cerevisiae.
Journal: The Journal of biological chemistry 20040430
Title: Stent thrombosis after successful sirolimus-eluting stent implantation.
Journal: Circulation 20040427
Title: Synergistic effects of sirolimus with cyclosporine and tacrolimus: analysis of immunosuppression on lymphocyte proliferation and activation in rat whole blood.
Journal: Transplantation 20040427
Title: Sirolimus-associated pulmonary toxicity.
Journal: Transplantation 20040427
Title: Comparison of sirolimus-based calcineurin inhibitor-sparing and calcineurin inhibitor-free regimens in cadaveric renal transplantation.
Journal: Transplantation 20040427
Title: Niban gene is commonly expressed in the renal tumors: a new candidate marker for renal carcinogenesis.
Journal: Oncogene 20040422
Title: Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases.
Journal: The EMBO journal 20040421
Title: Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status.
Journal: The Journal of biological chemistry 20040416
Title: Opioid-induced cardioprotection occurs via glycogen synthase kinase beta inhibition during reperfusion in intact rat hearts.
Journal: Circulation research 20040416
Title: TOR kinase and Ran are downstream from PI3K/Akt in H2O2-induced mitosis.
Journal: Journal of cellular biochemistry 20040415
Title: The novel cyclophilin binding compound, sanglifehrin A, disassociates G1 cell cycle arrest from tolerance induction.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040415
Title: Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone.
Journal: Blood 20040415
Title: Lymphedema associated with sirolimus in renal transplant recipients.
Journal: Transplantation 20040415
Title: TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae.
Journal: The Journal of biological chemistry 20040409
Title: Treatment of multivessel coronary artery disease with sirolimus-eluting stent implantation: immediate and mid-term results.
Journal: Journal of the American College of Cardiology 20040407
Title: Mammalian target of rapamycin regulates IRS-1 serine 307 phosphorylation.
Journal: Biochemical and biophysical research communications 20040402
Title: New rapamycin derivatives by precursor-directed biosynthesis.
Journal: Chembiochem : a European journal of chemical biology 20040402
Title: Rapamycin control of exocrine protein levels in saliva after adenoviral vector-mediated gene transfer.
Journal: Gene therapy 20040401
Title: Arginine and Leucine regulate p70 S6 kinase and 4E-BP1 in intestinal epithelial cells.
Journal: International journal of molecular medicine 20040401
Title: IL2-dependent phosphorylation of 40S ribosomal protein S6 is controlled by PI-3K/mTOR signalling in CTLL2 cells.
Journal: International journal of molecular medicine 20040401
Title: Multiple combination therapies involving blockade of ICOS/B7RP-1 costimulation facilitate long-term islet allograft survival.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040401
Title: Everolimus with optimized cyclosporine dosing in renal transplant recipients: 6-month safety and efficacy results of two randomized studies.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040401
Title: An investigation into signal transduction mechanisms involved in insulin-induced long-term depression in the CA1 region of the hippocampus.
Journal: Journal of neurochemistry 20040401
Title: Role of FKBP12.6 in hypoxia- and norepinephrine-induced Ca2+ release and contraction in pulmonary artery myocytes.
Journal: Cell calcium 20040401
Title: Rapamycin effects transcriptional programs in smooth muscle cells controlling proliferative and inflammatory properties.
Journal: Molecular pharmacology 20040401
Title: Safety and pharmacokinetics of ascending single doses of sirolimus (Rapamune, rapamycin) in pediatric patients with stable chronic renal failure undergoing dialysis.
Journal: Pediatric transplantation 20040401
Title: Short sirolimus half-life in pediatric renal transplant recipients on a calcineurin inhibitor-free protocol.
Journal: Pediatric transplantation 20040401
Title: Very long sirolimus-eluting stent implantation for de novo coronary lesions.
Journal: The American journal of cardiology 20040401
Title: Local drug delivery in restenosis injury: thermoresponsive co-polymers as potential drug delivery systems.
Journal: Pharmacology & therapeutics 20040401
Title: Immunosuppressants and skin cancer in transplant patients: focus on rapamycin.
Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20040401
Title: Clinical and angiographic outcomes after overdilatation of undersized sirolimus-eluting stents with largely oversized balloons: an observational study.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040401
Title: Overstretching undersized drug-eluting stents: a temporary solution.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040401
Title: Sirolimus-associated diffuse alveolar hemorrhage.
Journal: Mayo Clinic proceedings 20040401
Title: Dissociation of raptor from mTOR is a mechanism of rapamycin-induced inhibition of mTOR function.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20040401
Title: Sirolimus-eluting stents in the canine cerebral vasculature: a prospective, randomized, blinded assessment of safety and vessel response.
Journal: Journal of neurosurgery 20040401
Title: 'Real life' use of sirolimus-eluting coronary stents in Germany. Results from the prospective multi-centre German Cypher Registry.
Journal: Zeitschrift fur Kardiologie 20040401
Title: Sirolimus increases transforming growth factor-beta1 expression and potentiates chronic cyclosporine nephrotoxicity.
Journal: Kidney international 20040401
Title: Sirolimus in kidney transplantation from marginal donors.
Journal: Transplantation proceedings 20040401
Title: Platelet-Independent defect in hemostasis associated with sirolimus use.
Journal: Transplantation proceedings 20040401
Title: Severe rhabdomyolysis and acute renal failure in a kidney transplant patient treated with tacrolimus and chimaeric CD25 monoclonal antibody.
Journal: Transplantation proceedings 20040401
Title: PI3-kinase and TOR: PIKTORing cell growth.
Journal: Seminars in cell & developmental biology 20040401
Title: Islet allograft survival in nonhuman primates immunosuppressed with basiliximab, RAD, and FTY720.
Journal: Transplantation 20040327
Title: Therapeutic drug monitoring for sirolimus in whole blood of organ transplants by high-performance liquid chromatography with ultraviolet detection.
Journal: Journal of chromatography. A 20040326
Title: Clinical, angiographic, and procedural predictors of angiographic restenosis after sirolimus-eluting stent implantation in complex patients: an evaluation from the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) study.
Journal: Circulation 20040323
Title: Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
Journal: Biochemical and biophysical research communications 20040319
Title: Cancer: survival pathways meet their end.
Journal: Nature 20040318
Title: Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy.
Journal: Nature 20040318
Title: Differential regulation of MAP2 and alphaCamKII expression in hippocampal neurones by forskolin and calcium ionophore treatment.
Journal: Brain research. Molecular brain research 20040317
Title: The Canadian study of the sirolimus-eluting stent in the treatment of patients with long de novo lesions in small native coronary arteries (C-SIRIUS).
Journal: Journal of the American College of Cardiology 20040317
Title: Sirolimus-eluting stents: does a great stent still need a good interventionalist?
Journal: Journal of the American College of Cardiology 20040317
Title: Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions.
Journal: Circulation 20040316
Title: Unique, highly proliferative growth phenotype expressed by embryonic and neointimal smooth muscle cells is driven by constitutive Akt, mTOR, and p70S6K signaling and is actively repressed by PTEN.
Journal: Circulation 20040316
Title: Combination therapy with sirolimus and mycophenolate mofetil: effects on the kidney and on transforming growth factor-beta1.
Journal: Transplantation 20040315
Title: Conversion to sirolimus: a successful treatment for posttransplantation Kaposi's sarcoma.
Journal: Transplantation 20040315
Title: Molecular imaging of drug-modulated protein-protein interactions in living subjects.
Journal: Cancer research 20040315
Title: Rapamycin-induced endothelial cell death and tumor vessel thrombosis potentiate cytotoxic therapy against pancreatic cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040315
Title: Gln3 phosphorylation and intracellular localization in nutrient limitation and starvation differ from those generated by rapamycin inhibition of Tor1/2 in Saccharomyces cerevisiae.
Journal: The Journal of biological chemistry 20040312
Title: Contribution of stent underexpansion to recurrence after sirolimus-eluting stent implantation for in-stent restenosis.
Journal: Circulation 20040309
Title: Drug-eluting stent restenosis rates?
Journal: Circulation 20040309
Title: Protein kinase A phosphorylation at serine-2808 of the cardiac Ca2+-release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6).
Journal: Circulation research 20040305
Title: The mTOR/p70 S6K1 pathway regulates vascular smooth muscle cell differentiation.
Journal: American journal of physiology. Cell physiology 20040301
Title: Mammalian target of rapamycin (mTOR) Inhibitors.
Journal: Current oncology reports 20040301
Title: Rapamycin plays a new role as differentiator of vascular smooth muscle phenotype. focus on 'The mTOR/p70 S6K1 pathway regulates vascular smooth muscle differentiation'.
Journal: American journal of physiology. Cell physiology 20040301
Title: Evidence for 'lumen sealing' with sirolimus eluting stents in the treatment of complex coronary artery dissection.
Journal: Heart (British Cardiac Society) 20040301
Title: Long-term benefits with sirolimus-based therapy after early cyclosporine withdrawal.
Journal: Journal of the American Society of Nephrology : JASN 20040301
Title: Synergistic use of sirolimus-eluting stents and intravascular ultrasound for the treatment of unprotected left main and vein graft disease.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040301
Title: Electron microscopic and biochemical study of the effects of rapamycin on glycogen autophagy in the newborn rat liver.
Journal: Microscopy research and technique 20040301
Title: Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040301
Title: Treatment of very small vessels with 2.25-mm diameter sirolimus-eluting stents (from the RESEARCH registry).
Journal: The American journal of cardiology 20040301
Title: Economic impact of drug-eluting stents on hospital systems: a disease-state model.
Journal: American heart journal 20040301
Title: Cell signalling of glucagon-like peptide-1 action in rat skeletal muscle.
Journal: The Journal of endocrinology 20040301
Title: Steroid immunosuppression in kidney transplantation: a passing era.
Journal: The Journal of surgical research 20040301
Title: Blockage of 2-deoxy-D-ribose-induced angiogenesis with rapamycin counteracts a thymidine phosphorylase-based escape mechanism available for colon cancer under 5-fluorouracil therapy.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040301
Title: Sirolimus-eluting coronary stent.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040301
Title: Renal recovery after conversion to a calcineurin inhibitor-free immunosuppression in late cardiac transplant recipients.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20040301
Title: Effects of aerobic exercise training on the protein kinase B (PKB)/mammalian target of rapamycin (mTOR) signaling pathway in aged skeletal muscle.
Journal: Experimental gerontology 20040301
Title: Use of cyclosporine in renal transplantation.
Journal: Transplantation proceedings 20040301
Title: Immunosuppression for pancreatic islet transplantation.
Journal: Transplantation proceedings 20040301
Title: The evolving experience using everolimus in clinical transplantation.
Journal: Transplantation proceedings 20040301
Title: Experience with everolimus.
Journal: Transplantation proceedings 20040301
Title: The promise of C2, Simulect, and Certican in heart transplantation.
Journal: Transplantation proceedings 20040301
Title: Promise of Neoral C2, basiliximab, and everolimus in lung transplantation.
Journal: Transplantation proceedings 20040301
Title: Rapamycin analogs for stent-based local drug delivery. Everolimus- and tacrolimus-eluting stents.
Journal: Herz 20040301
Title: ABT-578-eluting stents. The promising successor of sirolimus- and paclitaxel-eluting stent concepts?
Journal: Herz 20040301
Title: Polymer-sirolimus-eluting stents in de novo lesions.
Journal: Herz 20040301
Title: [Safety and current indications during 'real life' use of sirolimus-eluting coronary stents in Germany. Results from the prospective multicenter German Cypher Registry].
Journal: Herz 20040301
Title: Classification and current treatment options of in-stent restenosis. Present status and future perspectives.
Journal: Herz 20040301
Title: Drug-eluting stents for in-stent restenosis and acute myocardial infarction: present data from nonrandomized studies.
Journal: Herz 20040301
Title: [Do drug-eluting stents influence the spectrum of coronary artery bypass surgery?].
Journal: Herz 20040301
Title: Drug eluting stents in the infrainguinal circulation.
Journal: Techniques in vascular and interventional radiology 20040301
Title: Cardiac allograft vasculopathy: advances in understanding its pathophysiology, prevention, and treatment.
Journal: Current opinion in cardiology 20040301
Title: Low toxicity immunosuppressive protocols in renal transplantation.
Journal: The Keio journal of medicine 20040301
Title: Molecule of the month. Everolimus.
Journal: Drug news & perspectives 20040301
Title: Rpd3p relocation mediates a transcriptional response to rapamycin in yeast.
Journal: Chemistry & biology 20040301
Title: Dose-dependent inhibition of myointimal hyperplasia by orally administered rapamycin.
Journal: Annals of vascular surgery 20040301
Title: Amino acids and insulin control autophagic proteolysis through different signaling pathways in relation to mTOR in isolated rat hepatocytes.
Journal: The Journal of biological chemistry 20040227
Title: Mycophenolate mofetil and sirolimus as calcineurin inhibitor-free immunosuppression for late cardiac-transplant recipients with chronic renal failure.
Journal: Transplantation 20040227
Title: Paradigm shifts in cardiovascular medicine.
Journal: Journal of the American College of Cardiology 20040218
Title: Short- and long-term clinical benefit of sirolimus-eluting stents compared to conventional bare stents for patients with acute myocardial infarction.
Journal: Journal of the American College of Cardiology 20040218
Title: Localized hypersensitivity and late coronary thrombosis secondary to a sirolimus-eluting stent: should we be cautious?
Journal: Circulation 20040217
Title: Mammalian target of rapamycin inhibition as therapy for hematologic malignancies.
Journal: Cancer 20040215
Title: Sirolimus and ketoconazole co-prescription in renal transplant recipients.
Journal: Transplantation 20040215
Title: Intravascular ultrasound study of effects of overlapping sirolimus-eluting stents.
Journal: The American journal of cardiology 20040215
Title: mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability.
Journal: Genes & development 20040215
Title: Analysis of 1-year clinical outcomes in the SIRIUS trial: a randomized trial of a sirolimus-eluting stent versus a standard stent in patients at high risk for coronary restenosis.
Journal: Circulation 20040210
Title: [New devices for coronary interventions in patients with acute coronary syndrome].
Journal: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20040210
Title: [Irritant cough and sub-febrile temperature under immunosuppression].
Journal: Praxis 20040204
Title: Dead cells don't form tumors: HIF-dependent cytotoxins.
Journal: Cell cycle (Georgetown, Tex.) 20040201
Title: Novel therapeutic molecular targets for prostate cancer: the mTOR signaling pathway and epidermal growth factor receptor.
Journal: The Journal of urology 20040201
Title: Mechanistic insights into impaired dendritic cell function by rapamycin: inhibition of Jak2/Stat4 signaling pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040201
Title: Regional haemodynamic effects of cyclosporine A, tacrolimus and sirolimus in conscious rats.
Journal: British journal of pharmacology 20040201
Title: Kissing sirolimus-eluting stents for the treatment of left main coronary artery stenosis.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040201
Title: Treatment of long, diffuse in-stent restenosis with sirolimus-eluting stents.
Journal: The Journal of invasive cardiology 20040201
Title: Effect of sirolimus on infection incidence in liver transplant recipients.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20040201
Title: Stent restenosis and the use of drug-eluting stents in patients with diabetes mellitus.
Journal: Current diabetes reports 20040201
Title: Determinants of rapamycin sensitivity in breast cancer cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040201
Title: [Is systematic use of drug-eluting stents justified? Arguments in favour].
Journal: Revista espanola de cardiologia 20040201
Title: [Is systematic use of drug-eluting stents justified? Arguments against].
Journal: Revista espanola de cardiologia 20040201
Title: [Sirolimus-eluting stents to treat lesions with a high risk of restenosis. Six-month clinical follow-up in the first 100 patients].
Journal: Revista espanola de cardiologia 20040201
Title: [Use of sirolimus-eluting stents in complex lesions: clinical and angiographic follow-up].
Journal: Revista espanola de cardiologia 20040201
Title: Inhibition of insulin signaling and adipogenesis by rapamycin: effect on phosphorylation of p70 S6 kinase vs eIF4E-BP1.
Journal: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20040201
Title: Human renal allograft rejection despite the absence of allogeneic passenger leukocytes.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040201
Title: Is everolimus useful in preventing allograft rejection and vasculopathy after heart transplant?
Journal: Expert opinion on investigational drugs 20040201
Title: Drug-eluting stents: a new treatment in the prevention of restenosis. Part I: Experimental studies.
Journal: Acta cardiologica 20040201
Title: [Thrombosis caused by active rapamycin stents].
Journal: Archives des maladies du coeur et des vaisseaux 20040201
Title: Everolimus: a proliferation signal inhibitor targeting primary causes of allograft dysfunction.
Journal: Drugs of today (Barcelona, Spain : 1998) 20040201
Title: Stents put on a new drug coat. The coat is thin and washes off, but offers major protection.
Journal: Heart advisor 20040201
Title: An open-label randomized trial of the safety and efficacy of sirolimus vs. azathioprine in living related renal allograft recipients receiving cyclosporine and prednisone combination.
Journal: Clinical transplantation 20040201
Title: Observations regarding the use of sirolimus and tacrolimus in high-risk cadaveric renal transplantation.
Journal: Clinical transplantation 20040201
Title: Nutrient-dependent and insulin-stimulated phosphorylation of insulin receptor substrate-1 on serine 302 correlates with increased insulin signaling.
Journal: The Journal of biological chemistry 20040130
Title: The N-terminal domain of yeast Bap2 permease is phosphorylated dependently on the Npr1 kinase in response to starvation.
Journal: FEMS microbiology letters 20040130
Title: Acceleration of apoptosis in CD4+CD8+ thymocytes by rapamycin accompanied by increased CD4+CD25+ T cells in the periphery.
Journal: Transplantation 20040127
Title: A randomized long-term trial of tacrolimus and sirolimus versus tacrolimus and mycophenolate mofetil versus cyclosporine (NEORAL) and sirolimus in renal transplantation. I. Drug interactions and rejection at one year.
Journal: Transplantation 20040127
Title: A randomized long-term trial of tacrolimus/sirolimus versus tacrolimus/mycophenolate mofetil versus cyclosporine (NEORAL)/sirolimus in renal transplantation. II. Survival, function, and protocol compliance at 1 year.
Journal: Transplantation 20040127
Title: Everolimus and mycophenolate mofetil are potent inhibitors of fibroblast proliferation after lung transplantation.
Journal: Transplantation 20040127
Title: AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression.
Journal: The Journal of biological chemistry 20040123
Title: Sirolimus-eluting coronary stents.
Journal: The New England journal of medicine 20040122
Title: Sirolimus-eluting coronary stents.
Journal: The New England journal of medicine 20040122
Title: Unrestricted utilization of sirolimus-eluting stents compared with conventional bare stent implantation in the 'real world': the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) registry.
Journal: Circulation 20040120
Title: Functional characterization of a maize ribosomal S6 protein kinase (ZmS6K), a plant ortholog of metazoan p70(S6K).
Journal: Biochemistry 20040120
Title: Bringing reality to drug-eluting stents.
Journal: Circulation 20040120
Title: 'Me-too' products--friend or foe?
Journal: The New England journal of medicine 20040115
Title: Thrombotic microangiopathy associated with combined sirolimus and tacrolimus immunosuppression after intestinal transplantation.
Journal: Transplantation 20040115
Title: Rapamycin inhibits cdk4 activation, p 21(WAF1/CIP1) expression and G1-phase progression in transformed mouse fibroblasts.
Journal: International journal of cancer 20040110
Title: Rapamycin-resistant proliferation of CD8+ T cells correlates with p27kip1 down-regulation and bcl-xL induction, and is prevented by an inhibitor of phosphoinositide 3-kinase activity.
Journal: The Journal of biological chemistry 20040109
Title: Golgi membranes remain segregated from the endoplasmic reticulum during mitosis in mammalian cells.
Journal: Cell 20040109
Title: Differential effects of modern immunosuppressive agents on the development of intimal hyperplasia.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20040101
Title: The role of phosphatases in TOR signaling in yeast.
Journal: Current topics in microbiology and immunology 20040101
Title: Nutrient signaling through TOR kinases controls gene expression and cellular differentiation in fungi.
Journal: Current topics in microbiology and immunology 20040101
Title: The fission yeast TOR proteins and the rapamycin response: an unexpected tale.
Journal: Current topics in microbiology and immunology 20040101
Title: Plant growth and the TOR pathway.
Journal: Current topics in microbiology and immunology 20040101
Title: TOR action in mammalian cells and in Caenorhabditis elegans.
Journal: Current topics in microbiology and immunology 20040101
Title: mTOR signaling to translation.
Journal: Current topics in microbiology and immunology 20040101
Title: Raptor and mTOR: subunits of a nutrient-sensitive complex.
Journal: Current topics in microbiology and immunology 20040101
Title: mTOR as a positive regulator of tumor cell responses to hypoxia.
Journal: Current topics in microbiology and immunology 20040101
Title: Retroviral oncogenes and TOR.
Journal: Current topics in microbiology and immunology 20040101
Title: mTOR as a target for cancer therapy.
Journal: Current topics in microbiology and immunology 20040101
Title: CYP3A4-transfected Caco-2 cells as a tool for understanding biochemical absorption barriers: studies with sirolimus and midazolam.
Journal: The Journal of pharmacology and experimental therapeutics 20040101
Title: Non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95) amplifies ionotropic glutamate receptor signaling in embryonic cerebellar granule neurons by a mechanism involving ryanodine receptors.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040101
Title: Drug-eluting stents. A review of the current literature.
Journal: Cardiology in review 20040101
Title: mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E.
Journal: Molecular and cellular biology 20040101
Title: Testosterone concentrations and sirolimus in male renal transplant patients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040101
Title: Sirolimus-induced pneumonitis: three cases and a review of the literature.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040101
Title: Intravascular ultrasound evaluation after sirolimus eluting stent implantation for de novo and in-stent restenosis lesions.
Journal: European heart journal 20040101
Title: Addition of sirolimus to cyclosporine delays the recovery from delayed graft function but does not affect 1-year graft function.
Journal: Journal of the American Society of Nephrology : JASN 20040101
Title: Stent fracture and restenosis in the drug-eluting stent era.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040101
Title: Rapamycin attenuates atherosclerosis induced by dietary cholesterol in apolipoprotein-deficient mice through a p27 Kip1 -independent pathway.
Journal: Atherosclerosis 20040101
Title: Health-related quality of life outcomes after kidney transplantation.
Journal: Health and quality of life outcomes 20040101
Title: Sirolimus-eluting stents inhibit neointimal hyperplasia in diabetic patients. Insights from the RAVEL Trial.
Journal: European heart journal 20040101
Title: Drug immunosuppression therapy for adult heart transplantation. Part 1: immune response to allograft and mechanism of action of immunosuppressants.
Journal: The Annals of thoracic surgery 20040101
Title: Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells.
Journal: Cancer research 20040101
Title: Rapamycin inhibits the growth and metastatic progression of non-small cell lung cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040101
Title: Clinical pharmacokinetics of everolimus.
Journal: Clinical pharmacokinetics 20040101
Title: [Prevention of in-stent restenosis: towards an in situ treatment?].
Journal: Medecine sciences : M/S 20040101
Title: Update on sirolimus drug-eluting stents.
Journal: Current pharmaceutical design 20040101
Title: Arsenite induces p70S6K1 activation and HIF-1alpha expression in prostate cancer cells.
Journal: Molecular and cellular biochemistry 20040101
Title: The management of immunosuppression: the art and the science.
Journal: Critical care nursing quarterly 20040101
Title: Transforming growth factor-beta induces Cdk2 relocalization to the cytoplasm coincident with dephosphorylation of retinoblastoma tumor suppressor protein.
Journal: Breast cancer research : BCR 20040101
Title: Everolimus/cyclosporine interactions on bile flow and biliary excretion of bile salts and cholesterol in rats.
Journal: Digestive diseases and sciences 20040101
Title: Sirolimus: a ten-year perspective.
Journal: Transplantation proceedings 20040101
Title: Adverse events and Cypher stents.
Journal: FDA consumer 20040101
Title: Immunophilin ligands decrease release of pro-inflammatory cytokines (IL-1beta, TNF-alpha and IL-2 in rat astrocyte cultures exposed to simulated ischemia in vitro.
Journal: Polish journal of pharmacology 20040101
Title: Everolimus.
Journal: Drugs 20040101
Title: Translation of the radioresistance kinase TLK1B is induced by gamma-irradiation through activation of mTOR and phosphorylation of 4E-BP1.
Journal: BMC molecular biology 20040101
Title: Lessons from the E-SIRIUS trial.
Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20040101
Title: Sirolimus-eluting coronary stents: novel devices for the management of coronary artery disease.
Journal: American journal of therapeutics 20040101
Title: Signaling of angiotensin II-induced vascular protein synthesis in conduit and resistance arteries in vivo.
Journal: BMC cardiovascular disorders 20040101
Title: New immunosuppressive strategies in renal transplant recipients.
Journal: Journal of nephrology 20040101
Title: Overcoming endocrine therapy resistance by signal transduction inhibition.
Journal: The oncologist 20040101
Title: Everolimus for stent-based intracoronary applications.
Journal: Reviews in cardiovascular medicine 20040101
Title: Liposomal formulations of tacrolimus and rapamycin increase graft survival and fiber outgrowth of dopaminergic grafts.
Journal: Cell transplantation 20040101
Title: Update on transplant pharmacology: sirolimus.
Journal: Dimensions of critical care nursing : DCCN 20040101
Title: [Stents without restenosis--true or a myth?].
Journal: Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti 20040101
Title: Conversion to sirolimus-based maintenance immunosuppression using daclizumab bridge therapy in renal transplant recipients.
Journal: Clinical transplantation 20040101
Title: Augmentation of T-cell apoptosis by immunosuppressive agents.
Journal: Clinical transplantation 20040101
Title: [De novo hemolytic uremic syndrome in a kidney-pancreas recipient in the postoperative period].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101
Title: [Interstitial pneumonitis associated with sirolimus administration in a renal transplantation patient: a clinical case].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101
Title: [Calcineurin-inhibitor-free immunosuppression in early renal transplantation].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101
Title: [Everolimus: immunosuppression with antilymphoproliferative therapy].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101
Title: Functional analysis of APC-Cdh1.
Journal: Methods in molecular biology (Clifton, N.J.) 20040101
Title: [Italian Consensus Conference on drug-eluting stents].
Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20040101
Title: Induction sirolimus and delayed graft function after deceased donor kidney transplantation in the United States.
Journal: American journal of nephrology 20040101
Title: Low-dose sirolimus in combination with mycophenolate mofetil improves kidney graft function late after renal transplantation and suggests pharmacokinetic interaction of both immunosuppressive drugs.
Journal: Kidney & blood pressure research 20040101
Title: Sirolimus dosage during and after conversion from calcineurin inhibitor therapy to sirolimus in chronic kidney transplant patients.
Journal: Kidney & blood pressure research 20040101
Title: New targets for therapy in breast cancer: mammalian target of rapamycin (mTOR) antagonists.
Journal: Breast cancer research : BCR 20040101
Title: [Vascular and interventional radiology].
Journal: Journal de radiologie 20040101
Title: Effect of rapamycin on cytokine profile in kidney transplant recipients treated with triple drug therapy.
Journal: Transplantation proceedings 20040101
Title: Donor stem cell infusion after non-myeloablative conditioning for tolerance induction to HLA mismatched adult living-donor liver graft.
Journal: Transplant immunology 20040101
Title: Immune status assay (ISA): a noninvasive procedure for studying allograft rejection.
Journal: Transplant immunology 20040101
Title: Method development for the quantitation of ABT-578 in rabbit artery tissue by 96-well liquid-liquid extraction and liquid chromatography/tandem mass spectrometric detection.
Journal: Rapid communications in mass spectrometry : RCM 20040101
Title: Empirical assessment of the impact of drug-eluting stents on the rate of use of coronary revascularization procedures.
Journal: International journal of technology assessment in health care 20040101
Title: Addition of heparin to contrast media is associated with increased bleeding and peripheral vascular complications during percutaneous coronary intervention with bivalirudin and drug-eluting stents.
Journal: Cardiovascular radiation medicine 20040101
Title: Molecular targeting: PI3 kinase pathway.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20040101
Title: Pamidronate resistance and associated low ras levels in breast cancer cells: a role for combinatorial therapy.
Journal: Annals of clinical and laboratory science 20040101
Title: [First experience of the use of sirolimus covered stents output in the treatment of ischemic heart disease].
Journal: Kardiologiia 20040101
Title: Asymptomatic late stent thrombosis after sirolimus stent implantation.
Journal: Cardiovascular radiation medicine 20040101
Title: Rapamycin inhibits Akt-mediated oncogenic transformation and tumor growth.
Journal: Anticancer research 20040101
Title: Drug-coated stents: preventing restenosis in coronary artery disease.
Journal: The Journal of cardiovascular nursing 20040101
Title: [Restenosis inside the stent: treatment and prevention].
Journal: Klinicheskaia meditsina 20040101
Title: Temsirolimus: CCI 779, CCI-779, cell cycle inhibitor-779.
Journal: Drugs in R&D 20040101
Title: Immunomodulatory therapy in ophthalmology - is there a place for topical application?
Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20040101
Title: Therapeutic monitoring of immunosuppressant drugs. Where are we?
Journal: Clinical chemistry and laboratory medicine 20040101
Title: The pleiotropic effects of mTor inhibitors.
Journal: Journal of nephrology 20040101
Title: Sirolimus-based immunosuppression: present state of the art.
Journal: Journal of nephrology 20040101
Title: From balloon angioplasty to drug-eluting stents: revolution or evolution?
Journal: The American heart hospital journal 20040101
Title: Drug-eluting stents: are they really safe?
Journal: The American heart hospital journal 20040101
Title: Differential effects of rapamycin, cyclosporine A, and FK506 on human coronary artery smooth muscle cell proliferation and signalling.
Journal: Vascular pharmacology 20040101
Title: Sirolimus therapy in orthotopic liver transplant (OLT) recipients with acute renal insufficiency.
Journal: Digestive diseases and sciences 20040101
Title: [Cancer after kidney transplantation].
Journal: Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20040101
Title: An evidence-based approach to the use of drug-eluting stents in clinical practice.
Journal: The American heart hospital journal 20040101
Title: Late thrombosis in cypher stents after the discontinuation of antiplatelet therapy.
Journal: Cardiovascular radiation medicine 20040101
Title: CNI-sparing regimens within the liver transplant setting: experiences of a single center.
Journal: Clinical transplants 20040101
Title: The impact of sirolimus, mycophenolate mofetil, cyclosporine, azathioprine, and steroids on wound healing in 513 kidney-transplant recipients.
Journal: Transplantation 20031227
Title: Sirolimus inhibits oxidative burst activity in transplant recipients.
Journal: Transplantation 20031227
Title: Sirolimus myopathy.
Journal: Transplantation 20031227
Title: Rapamycin induces the fusion-type independent downregulation of the EWS/FLI-1 proteins and inhibits Ewing's sarcoma cell proliferation.
Journal: Oncogene 20031218
Title: Blocking the monocyte chemoattractant protein-1/CCR2 chemokine pathway induces permanent survival of islet allografts through a programmed death-1 ligand-1-dependent mechanism.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20031215
Title: Sirolimus delays recovery of rat kidney transplants after ischemia-reperfusion injury.
Journal: Transplantation 20031215
Title: Elevated portal vein drug levels of sirolimus and tacrolimus in islet transplant recipients: local immunosuppression or islet toxicity?
Journal: Transplantation 20031215
Title: Sirolimus-atorvastatin drug interaction in the pancreatic islet transplant recipient.
Journal: Transplantation 20031215
Title: Everolimus in cardiac-transplant recipients.
Journal: The New England journal of medicine 20031204
Title: Long-term follow-up of incomplete stent apposition in patients who received sirolimus-eluting stent for de novo coronary lesions: an intravascular ultrasound analysis.
Journal: Circulation 20031202
Title: Insulin-dependent signaling regulates azurophil granule-selective macroautophagy in human myeloblastic cells.
Journal: Journal of leukocyte biology 20031201
Title: Long-term treatment with insulin induces apoptosis in brown adipocytes: role of oxidative stress.
Journal: Endocrinology 20031201
Title: Ortho-substituted PCBs kill thymocytes.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20031201
Title: New therapeutic strategies for soft tissue sarcomas.
Journal: Current treatment options in oncology 20031201
Title: Homodirectional changes in transcriptome composition and mRNA translation induced by rapamycin and heat shock.
Journal: Nature structural biology 20031201
Title: Pharmacologic prevention of both restenosis and atherosclerosis progression: AGI-1067, probucol, statins, folic acid and other therapies.
Journal: Current opinion in lipidology 20031201
Title: Restenosis due to underexpansion of sirolimus-eluting stent in a bifurcation lesion.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20031201
Title: Late stent thrombosis after implantation of a sirolimus-eluting stent.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20031201
Title: The porcine coronary model of in-stent restenosis: current status in the era of drug-eluting stents.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20031201
Title: Influence of delayed initiation of cyclosporine on everolimus pharmacokinetics in de novo renal transplant patients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20031201
Title: Antiproliferative coatings for the treatment of coronary heart disease:. what are the targets and which are the tools?
Journal: Journal of interventional cardiology 20031201
Title: Treatment of bifurcation coronary lesions: a review of current techniques and outcome.
Journal: Journal of interventional cardiology 20031201
Title: Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: the National Institutes of Health experience.
Journal: Diabetes care 20031201
Title: Usefulness of shear stress pattern in predicting neointima distribution in sirolimus-eluting stents in coronary arteries.
Journal: The American journal of cardiology 20031201
Title: Assessment of immunosuppressive drug interactions: inhibition of lymphocyte function in peripheral human blood.
Journal: Journal of immunological methods 20031201
Title: Differential effects of rapamycin on mammalian target of rapamycin signaling functions in mammalian cells.
Journal: Cancer research 20031201
Title: Rapamycin has no effect on fibrosis-associated gene expression or extracellular matrix accumulation when administered to animals with established or early allograft vasculopathy.
Journal: The Journal of thoracic and cardiovascular surgery 20031201
Title: TOR and PKA signaling pathways converge on the protein kinase Rim15 to control entry into G0.
Journal: Molecular cell 20031201
Title: Conditional protein alleles using knockin mice and a chemical inducer of dimerization.
Journal: Molecular cell 20031201
Title: Sirolimus therapy in orthotopic liver transplant recipients with calcineurin inhibitor related chronic renal insufficiency.
Journal: Transplantation proceedings 20031201
Title: Effect of sirolimus on the cholesterol content of aortic arch in ApoE knockout mice.
Journal: Transplantation proceedings 20031201
Title: Regulating cell surface glycosylation by small molecule control of enzyme localization.
Journal: Chemistry & biology 20031201
Title: [Immunomodulation in penetrating keratoplasty. Current status and perspectives].
Journal: Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20031201
Title: Current immunosuppressive agents: efficacy, side effects, and utilization.
Journal: Pediatric clinics of North America 20031201
Title: The arsenal. The latest in drugs, surgery, and devices.
Journal: U.S. news & world report 20031201
Title: Sirolimus add-on rescue therapy can benefit patients with chronic renal allograft dysfunction.
Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20031201
Title: Angioplasty: no more repeats.
Journal: The Johns Hopkins medical letter health after 50 20031201
Title: Low incidence of cytomegalovirus disease in liver transplant recipients receiving sirolimus primary immunosuppression with 3-day corticosteroid taper.
Journal: Transplant infectious disease : an official journal of the Transplantation Society 20031201
Title: Ser-64 and Ser-111 in PHAS-I are dispensable for insulin-stimulated dissociation from eIF4E.
Journal: The Journal of biological chemistry 20031128
Title: [Are drug-coated stents too expensive?].
Journal: Deutsche medizinische Wochenschrift (1946) 20031121
Title: Atrophic remodeling of the heart in vivo simultaneously activates pathways of protein synthesis and degradation.
Journal: Circulation 20031118
Title: Chromatin-mediated regulation of nucleolar structure and RNA Pol I localization by TOR.
Journal: The EMBO journal 20031117
Title: Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscle.
Journal: The Journal of physiology 20031115
Title: Control of nutrient-sensitive transcription programs by the unconventional prefoldin URI.
Journal: Science (New York, N.Y.) 20031114
Title: Akt promotes increased mammalian cell size by stimulating protein synthesis and inhibiting protein degradation.
Journal: American journal of physiology. Endocrinology and metabolism 20031101
Title: Characterization of the transport of the bicyclic peptide phalloidin by human hepatic transport proteins.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20031101
Title: Rapamycin antagonizes cyclosporin A- and tacrolimus (FK506)-mediated augmentation of linker for activation of T cell expression in T cells.
Journal: International immunology 20031101
Title: Sirolimus-induced interstitial pneumonitis in an islet transplant recipient.
Journal: Diabetes care 20031101
Title: Rapamycin has a deleterious effect on MIN-6 cells and rat and human islets.
Journal: Diabetes 20031101
Title: Macrophage colony-stimulating factor-dependent macrophage proliferation is mediated through a calcineurin-independent but immunophilin-dependent mechanism that mediates the activation of external regulated kinases.
Journal: European journal of immunology 20031101
Title: Design and structure-based study of new potential FKBP12 inhibitors.
Journal: Biophysical journal 20031101
Title: Angiographic regression of cardiac allograft vasculopathy after introducing sirolimus immunosuppression.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20031101
Title: Multi-lesion culotte and crush bifurcation stenting with sirolimus-eluting stents: long-term angiographic outcome.
Journal: The Journal of invasive cardiology 20031101
Title: Low-dose sirolimus in combination with mycophenolate in calcineurin inhibitor elimination: the Kuwaiti experience.
Journal: Transplantation proceedings 20031101
Title: Induction of protein synthesis in cardiac fibroblasts by cardiotrophin-1: integration of multiple signaling pathways.
Journal: Cardiovascular research 20031101
Title: The role of nitrate reductase in the regulation of the nitrate assimilation pathway in the yeast Hansenula polymorpha.
Journal: FEMS yeast research 20031101
Title: Determination of the pharmacokinetics of cerivastatin when administered in combination with sirolimus and cyclosporin A in patients with kidney transplant, and review of the relevant literature.
Journal: International journal of clinical pharmacology and therapeutics 20031101
Title: Drug-eluting stents in peripheral vascular disease: eliminating restenosis.
Journal: The Mount Sinai journal of medicine, New York 20031101
Title: Will mTOR inhibitors make it as cancer drugs?
Journal: Cancer cell 20031101
Title: Immunosuppression in renal transplantation: where are we now?
Journal: Hospital medicine (London, England : 1998) 20031101
Title: Bibliography. Current world literature. Therapeutic modalities.
Journal: Current opinion in oncology 20031101
Title: Differential effect of cyclosporine A and SDZ RAD on neointima formation of carotid allografts in apolipoprotein E-deficient mice.
Journal: Transplantation 20031027
Title: Sirolimus-eluting stent implantation in ST-elevation acute myocardial infarction: a clinical and angiographic study.
Journal: Circulation 20031021
Title: Target of rapamycin (TOR)-signaling and RAIP motifs play distinct roles in the mammalian TOR-dependent phosphorylation of initiation factor 4E-binding protein 1.
Journal: The Journal of biological chemistry 20031017
Title: Drug-eluting stents substantially lower rate of restenosis.
Journal: Report on medical guidelines & outcomes research 20031017
Title: Insulin independence after conversion to tacrolimus and sirolimus-based immunosuppression in islet-kidney recipients.
Journal: Transplantation 20031015
Title: Involvement of the VDE homing endonuclease and rapamycin in regulation of the Saccharomyces cerevisiae GSH11 gene encoding the high affinity glutathione transporter.
Journal: The Journal of biological chemistry 20031010
Title: Drug-delivering coronary artery stents: bare metal threatened by extinction?
Journal: Lancet (London, England) 20031004
Title: Sirolimus-eluting stents for treatment of patients with long atherosclerotic lesions in small coronary arteries: double-blind, randomised controlled trial (E-SIRIUS).
Journal: Lancet (London, England) 20031004
Title: Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2.
Journal: The Journal of biological chemistry 20031003
Title: Sirolimus for the prevention of in-stent restenosis in a coronary artery.
Journal: The New England journal of medicine 20031002
Title: Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery.
Journal: The New England journal of medicine 20031002
Title: Beta-adrenergic agonists regulate Na-K-ATPase via p70S6k.
Journal: American journal of physiology. Lung cellular and molecular physiology 20031001
Title: Amino acid transport regulates blastocyst implantation.
Journal: Biology of reproduction 20031001
Title: Rapamycin-based rescue therapy after chronic rejection in a pediatric liver transplant patient.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20031001
Title: Tissue-specific regulation of protein synthesis by insulin and free fatty acids.
Journal: American journal of physiology. Endocrinology and metabolism 20031001
Title: Cytokines regulate the pattern of rejection and susceptibility to cyclosporine therapy in different mouse recipient strains after cardiac allografting.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20031001
Title: M-CSF, TNFalpha and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase.
Journal: Cell death and differentiation 20031001
Title: Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade.
Journal: Nature medicine 20031001
Title: Determination of sirolimus blood concentration using high-performance liquid chromatography with ultraviolet detection.
Journal: Therapeutic drug monitoring 20031001
Title: Pharmacokinetic interactions between sirolimus and microemulsion cyclosporine when orally administered jointly and 4 hours apart in healthy volunteers.
Journal: Journal of clinical pharmacology 20031001
Title: Pilot study of oral rapamycin to prevent restenosis in patients undergoing coronary stent therapy: Argentina Single-Center Study (ORAR Trial).
Journal: The Journal of invasive cardiology 20031001
Title: [Non cardiac surgery in patient with coronary stenting: think sirolimus now!].
Journal: Annales francaises d'anesthesie et de reanimation 20031001
Title: Renal function improves in liver transplant recipients when switched from a calcineurin inhibitor to sirolimus.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20031001
Title: Negative regulation of interleukin-12 production by a rapamycin-sensitive signaling pathway: a brief communication.
Journal: Experimental biology and medicine (Maywood, N.J.) 20031001
Title: Rapamycin preserves renal function compared with cyclosporine A after ischemia/reperfusion injury.
Journal: Urology 20031001
Title: Everolimus in de novo cardiac transplantation: pharmacokinetics, therapeutic range, and influence on cyclosporine exposure.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20031001
Title: Sirolimus-eluting stents for the treatment of in-stent restenosis.
Journal: Minerva cardioangiologica 20031001
Title: Evolving standard in the treatment of coronary artery disease. Drug-eluting stents.
Journal: Minerva cardioangiologica 20031001
Title: Using intravascular ultrasound with drug-eluting stents. What have we learned so far?
Journal: Minerva cardioangiologica 20031001
Title: Attachment of the ubiquitin-related protein Urm1p to the antioxidant protein Ahp1p.
Journal: Eukaryotic cell 20031001
Title: Excellent short-term results with steroid-free maintenance immunosuppression in low-risk simultaneous pancreas-kidney transplantation.
Journal: Archives of surgery (Chicago, Ill. : 1960) 20031001
Title: The PCPH oncoprotein antagonizes the proapoptotic role of the mammalian target of rapamycin in the response of normal fibroblasts to ionizing radiation.
Journal: Cancer research 20031001
Title: Drug-eluting stents and glycoprotein IIb/IIIa inhibitors: combination therapy for the future.
Journal: American heart journal 20031001
Title: Posterior leukoencephalopathy with cyclosporine.
Journal: Clinical nephrology 20031001
Title: Immunosuppression in liver transplantation.
Journal: Minerva chirurgica 20031001
Title: [Perspectives of pharmacological anti-proliferative therapy for arteriosclerosis].
Journal: Recenti progressi in medicina 20031001
Title: Drug-eluting versus bare metal coronary stents: long-term human pathology. Findings from different coronary arteries in the same patient.
Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20031001
Title: Withdrawal of steroid therapy in African American kidney transplant recipients receiving sirolimus and tacrolimus.
Journal: Transplantation 20030927
Title: Tor1/2 regulation of retrograde gene expression in Saccharomyces cerevisiae derives indirectly as a consequence of alterations in ammonia metabolism.
Journal: The Journal of biological chemistry 20030919
Title: Anti-third-party veto CTLs overcome rejection of hematopoietic allografts: synergism with rapamycin and BM cell dose.
Journal: Blood 20030915
Title: Rapamycin-induced oligospermia.
Journal: Transplantation 20030915
Title: Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin.
Journal: Cancer research 20030915
Title: Mitogenic effect of glial cell line-derived neurotrophic factor is dependent on the activation of p70S6 kinase, but independent of the activation of ERK and up-regulation of Ret in SH-SY5Y cells.
Journal: Brain research 20030905
Title: Conditional protein splicing: a new tool to control protein structure and function in vitro and in vivo.
Journal: Journal of the American Chemical Society 20030903
Title: Rapamycin causes down-regulation of CCR5 and accumulation of anti-HIV beta-chemokines: an approach to suppress R5 strains of HIV-1.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20030902
Title: Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation.
Journal: Blood 20030901
Title: Drosophila Rheb GTPase is required for cell cycle progression and cell growth.
Journal: Journal of cell science 20030901
Title: Comparison of sirolimus vs. mycophenolate mofetil on surgical complications and wound healing in adult kidney transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030901
Title: Oral rapamycin in the treatment of diffuse proliferative in-stent restenosis in a patient with small reference vessel.
Journal: The Journal of invasive cardiology 20030901
Title: Involvement of the Akt/mTOR pathway on EGF-induced cell transformation.
Journal: Molecular carcinogenesis 20030901
Title: The long-term survival of baboon-to-monkey kidney and liver xenografts.
Journal: Xenotransplantation 20030901
Title: Parallel purification of three catalytic subunits of the protein serine/threonine phosphatase 2A family (PP2A(C), PP4(C), and PP6(C)) and analysis of the interaction of PP2A(C) with alpha4 protein.
Journal: Protein expression and purification 20030901
Title: Second window of protection following myocardial preconditioning: an essential role for PI3 kinase and p70S6 kinase.
Journal: Journal of molecular and cellular cardiology 20030901
Title: Rapamycin treatment at immunosuppressive doses affects tumor blood vessel circulation.
Journal: Transplantation proceedings 20030901
Title: Rapamycin in children after liver transplantation.
Journal: Transplantation proceedings 20030901
Title: Pathologic assessment of cardiomyocytes in heart transplant recipients treated with rapamycin or cyclosporine.
Journal: Transplantation proceedings 20030901
Title: Deterioration of renal function after replacement of cyclosporine with sirolimus in five patients with severe renal impairment late after heart transplantation.
Journal: Transplantation proceedings 20030901
Title: Restenosis in percutaneous coronary intervention--is drug-eluting stent the answer?
Journal: Singapore medical journal 20030901
Title: Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner.
Journal: The Journal of biological chemistry 20030829
Title: Rapamycin inhibits GM-CSF-induced neutrophil migration.
Journal: FEBS letters 20030828
Title: Cardiac-allograft vasculopathy.
Journal: The New England journal of medicine 20030828
Title: Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients.
Journal: The New England journal of medicine 20030828
Title: LF 15-0195, a novel immunosuppressive agent prevents rejection and induces operational tolerance in a mouse cardiac allograft model.
Journal: Transplantation 20030827
Title: Muscarinic receptor-mediated activation of p70 S6 kinase 1 (S6K1) in 1321N1 astrocytoma cells: permissive role of phosphoinositide 3-kinase.
Journal: The Biochemical journal 20030815
Title: Synergistic effects of CTLA-4Ig and sirolimus on orthotopic lung-allograft survival and histology.
Journal: Transplantation 20030815
Title: Apoptosis and treatment of chronic allograft nephropathy with everolimus.
Journal: Transplantation 20030815
Title: Successful infliximab treatment of steroid and OKT3 refractory acute cellular rejection in two patients after intestinal transplantation.
Journal: Transplantation 20030815
Title: Chronic myeloid leukemia: pathophysiology, diagnostic parameters, and current treatment concepts.
Journal: Wiener klinische Wochenschrift 20030814
Title: CYPHER coronary stents and risk of thrombosis.
Journal: CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20030805
Title: Survival of acute myeloid leukemia cells requires PI3 kinase activation.
Journal: Blood 20030801
Title: Intestinal sugar absorption is regulated by phosphorylation and turnover of protein kinase C betaII mediated by phosphatidylinositol 3-kinase- and mammalian target of rapamycin-dependent pathways.
Journal: The Journal of biological chemistry 20030801
Title: Divergence in signaling pathways involved in promotion of cell viability mediated by bFGF, NGF, and EGF in PC12 cells.
Journal: Neurochemical research 20030801
Title: The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor.
Journal: Genes & development 20030801
Title: Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling.
Journal: Genes & development 20030801
Title: The phosphatidylinositol-3 kinase (PI3K)-Akt pathway suppresses neurite branch formation in NGF-treated PC12 cells.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20030801
Title: Long-term pharmacokinetic study of the novel combination of tacrolimus and sirolimus in de novo renal allograft recipients.
Journal: Therapeutic drug monitoring 20030801
Title: Effectiveness of sirolimus-eluting stent for treatment of left main coronary artery disease.
Journal: The American journal of cardiology 20030801
Title: Effects of FK506 and rapamycin on generation of reactive oxygen species, nitric oxide production and nuclear factor kappa B activation in rat hepatocytes.
Journal: Biochemical pharmacology 20030801
Title: Rapamycin inhibits the interleukin 10 signal transduction pathway and the growth of Epstein Barr virus B-cell lymphomas.
Journal: Cancer research 20030801
Title: Immunophilins, mTOR, and pharmacodynamic strategies for a targeted cancer therapy.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030801
Title: Pharmacodynamic Evaluation of CCI-779, an Inhibitor of mTOR, in Cancer Patients.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030801
Title: Rapamycin-sensitive signalling in long-term consolidation of auditory cortex-dependent memory.
Journal: The European journal of neuroscience 20030801
Title: Postgrafting immunosuppression with sirolimus and cyclosporine facilitates stable mixed hematopoietic chimerism in dogs given sublethal total body irradiation before marrow transplantation from DLA-identical littermates.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20030801
Title: Rapamycin inhibits telomerase activity by decreasing the hTERT mRNA level in endometrial cancer cells.
Journal: Molecular cancer therapeutics 20030801
Title: Treatment of idiopathic nephrosis by immunophillin modulation.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030801
Title: TSC2 regulates VEGF through mTOR-dependent and -independent pathways.
Journal: Cancer cell 20030801
Title: Early elimination of cyclosporine in kidney transplant recipients receiving sirolimus prevents progression of chronic pathologic allograft lesions.
Journal: Transplantation proceedings 20030801
Title: Defining the initial doses of sirolimus and tacrolimus in the period immediately after renal transplantation.
Journal: Transplantation proceedings 20030801
Title: Rapamycin in lung transplantation: preliminary results.
Journal: Transplantation proceedings 20030801
Title: Sirolimus in heart transplantation: a single center initial experience.
Journal: Transplantation proceedings 20030801
Title: Integration of growth factor and nutrient signaling: implications for cancer biology.
Journal: Molecular cell 20030801
Title: Retrograde signaling is regulated by the dynamic interaction between Rtg2p and Mks1p.
Journal: Molecular cell 20030801
Title: Sirolimus-induced interstitial pneumonitis in a renal transplant recipient.
Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20030801
Title: Sirolimus does not increase the risk for postoperative thromboembolic events among renal transplant recipients.
Journal: Transplantation 20030727
Title: Long-term improvement in renal function with sirolimus after early cyclosporine withdrawal in renal transplant recipients: 2-year results of the Rapamune Maintenance Regimen Study.
Journal: Transplantation 20030727
Title: Dyslipidemia in renal transplant recipients treated with a sirolimus and cyclosporine-based immunosuppressive regimen: incidence, risk factors, progression, and prognosis.
Journal: Transplantation 20030727
Title: Higher surgical wound complication rates with sirolimus immunosuppression after kidney transplantation: a matched-pair pilot study.
Journal: Transplantation 20030727
Title: Mechanism of ribosomal p70S6 kinase activation by granulocyte macrophage colony-stimulating factor in neutrophils: cooperation of a MEK-related, THR421/SER424 kinase and a rapamycin-sensitive, m-TOR-related THR389 kinase.
Journal: The Journal of biological chemistry 20030725
Title: Coronary restenosis after sirolimus-eluting stent implantation: morphological description and mechanistic analysis from a consecutive series of cases.
Journal: Circulation 20030722
Title: Restenosis: the mouse that roared.
Journal: Circulation 20030722
Title: Modulation of translation-initiation in CHO-K1 cells by rapamycin-induced heterodimerization of engineered eIF4G fusion proteins.
Journal: Biotechnology and bioengineering 20030720
Title: Hyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytes.
Journal: The Journal of biological chemistry 20030718
Title: Mutational analysis of ribosomal S6 kinase 2 shows differential regulation of its kinase activity from that of ribosomal S6 kinase 1.
Journal: The Biochemical journal 20030715
Title: Ca(2+)-independent protein kinase C activity is required for alpha1-adrenergic-receptor-mediated regulation of ribosomal protein S6 kinases in adult cardiomyocytes.
Journal: The Biochemical journal 20030715
Title: Effectiveness of sirolimus-eluting stent implantation for recurrent in-stent restenosis after brachytherapy.
Journal: The American journal of cardiology 20030715
Title: Rabbit antithymocyte globulin induction and sirolimus monotherapy supports prolonged islet allograft function in a nonhuman primate islet transplantation model.
Journal: Transplantation 20030715
Title: Novel sulfur-containing rapamycin analogs prepared by precursor-directed biosynthesis.
Journal: Organic letters 20030710
Title: Differential translation of TOP mRNAs in rapamycin-treated human B lymphocytes.
Journal: Biochimica et biophysica acta 20030709
Title: Use of rapamycin slows progression of cardiac transplantation vasculopathy.
Journal: Circulation 20030708
Title: Rapamycin for cardiac transplant rejection and vasculopathy: one stone, two birds?
Journal: Circulation 20030708
Title: Rapamycin slows heart transplant vasculopathy.
Journal: Circulation 20030708
Title: Alpha-Synuclein is degraded by both autophagy and the proteasome.
Journal: The Journal of biological chemistry 20030704
Title: Sirolimus and mycophenolate mofetil after liver transplantation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20030701
Title: Effects of cyclosporin A and a rapamycin derivative (SAR943) on chronic allergic inflammation in sensitized rats.
Journal: Immunology 20030701
Title: The role of c-Myc on granulocyte colony-stimulating factor-dependent neutrophilic proliferation and differentiation of HL-60 cells.
Journal: Biochemical pharmacology 20030701
Title: Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways.
Journal: The American journal of pathology 20030701
Title: Interstitial granulomatous pneumonitis associated with sirolimus in a child after liver transplantation.
Journal: Journal of pediatric gastroenterology and nutrition 20030701
Title: Effects of immunomodulators on airways hyperresponsiveness to adenosine induced in actively sensitised Brown Norway rats by exposure to allergen.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030701
Title: Sirolimus-induced thrombotic microangiopathy in a renal transplant recipient.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20030701
Title: The influence of the rapamycin-derivate SDZ RAD on the healing of airway anastomoses.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20030701
Title: 'Cyclosporine-sparing' regimen approved.
Journal: The American journal of nursing 20030701
Title: [Position paper on the use of drug eluting stents (DES) in percutaneous coronary interventions in patients with coronary heart disease].
Journal: Zeitschrift fur Kardiologie 20030701
Title: Mutant type glutathione S-transferase theta 1 gene homologue to mTOR in myelodysplastic syndrome: possible clinical application of rapamycin.
Journal: Leukemia & lymphoma 20030701
Title: New stents, hopes--and questions. After approval of a drug-coated cylinder, patients face wider options.
Journal: Heart advisor 20030701
Title: High-throughput liquid chromatography-tandem mass spectrometric analysis of sirolimus in whole blood.
Journal: Clinical chemistry and laboratory medicine 20030701
Title: mTOR inhibitors in hematologic malignancies.
Journal: Clinical advances in hematology & oncology : H&O 20030701
Title: A prospective randomized multicenter study of tacrolimus in combination with sirolimus in renal-transplant recipients.
Journal: Transplantation 20030627
Title: Everolimus in pediatric de nova renal transplant patients.
Journal: Transplantation 20030627
Title: Treatment with humanized monoclonal antibodies against CD80 and CD86 combined with sirolimus prolongs renal allograft survival in cynomolgus monkeys.
Journal: Transplantation 20030627
Title: Primary intestinal posttransplant T-cell lymphoma.
Journal: Transplantation 20030627
Title: Phospholipase D confers rapamycin resistance in human breast cancer cells.
Journal: Oncogene 20030619
Title: Induction of apoptosis in IL-3-dependent hematopoietic cell lines by guanine nucleotide depletion.
Journal: Blood 20030615
Title: Proliferation and survival of activated B cells requires sustained antigen receptor engagement and phosphoinositide 3-kinase activation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030615
Title: Pharmacologically regulated production of targeted retrovirus from T cells for systemic antitumor gene therapy.
Journal: Cancer research 20030615
Title: Long-term islet allograft survival in nonobese diabetic mice treated with tacrolimus, rapamycin, and anti-interleukin-2 antibody.
Journal: Transplantation 20030615
Title: First drug-eluting coronary stent approved.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20030615
Title: Regulation of the phosphatidylinositol 3-kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and stimulating type TSH receptor antibodies in the thyroid gland.
Journal: The Journal of biological chemistry 20030613
Title: Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2 alpha kinase GCN2.
Journal: The Journal of biological chemistry 20030606
Title: Early outcome after sirolimus-eluting stent implantation in patients with acute coronary syndromes: insights from the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) registry.
Journal: Journal of the American College of Cardiology 20030604
Title: Rapamycin inhibits IL-4--induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo.
Journal: Blood 20030601
Title: Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability.
Journal: The Biochemical journal 20030601
Title: p38 MAP kinase regulates BMP-4-stimulated VEGF synthesis via p70 S6 kinase in osteoblasts.
Journal: American journal of physiology. Endocrinology and metabolism 20030601
Title: Campath-1H induction plus rapamycin monotherapy for renal transplantation: results of a pilot study.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030601
Title: Influence of SDZ RAD vs. MMF on gastric emptying in renal transplant recipients.
Journal: Clinical transplantation 20030601
Title: Single HSV-amplicon vector mediates drug-induced gene expression via dimerizer system.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20030601
Title: The evolving role of sirolimus in renal transplantation.
Journal: QJM : monthly journal of the Association of Physicians 20030601
Title: Phase I and pharmacokinetic study of CCI-779, a novel cytostatic cell-cycle inhibitor, in combination with 5-fluorouracil and leucovorin in patients with advanced solid tumors.
Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20030601
Title: Rapamycin treatment results in GATA factor-independent hyperphosphorylation of the proline utilization pathway activator in Saccharomyces cerevisiae.
Journal: Eukaryotic cell 20030601
Title: Vanadate and rapamycin synergistically enhance insulin-stimulated glucose uptake.
Journal: Metabolism: clinical and experimental 20030601
Title: Multiple roles of Tap42 in mediating rapamycin-induced transcriptional changes in yeast.
Journal: Molecular cell 20030601
Title: Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21(Cip1).
Journal: Molecular cell 20030601
Title: The rush is on to acquire drug-eluting stents.
Journal: Hospital material[dollar sign] management 20030601
Title: Rapid conversion to sirolimus for chronic progressive deterioration of the renal function in kidney allograft recipients.
Journal: Transplantation proceedings 20030601
Title: Opening the shut cases. Drug-coated stents may solve the biggest problem with angioplasty--keeping coronary arteries open.
Journal: Harvard health letter 20030601
Title: In vitro immunomodulatory activity of ruthenium complexes.
Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030601
Title: Mammalian target of rapamycin: a new molecular target for breast cancer.
Journal: Clinical breast cancer 20030601
Title: [Drug-eluting stents in complex lesions].
Journal: Annales de cardiologie et d'angeiologie 20030601
Title: [In-stent restenosis: which indications for drug-eluting stent?].
Journal: Annales de cardiologie et d'angeiologie 20030601
Title: Sirolimus: a current perspective.
Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20030601
Title: Immunosuppressive TOR kinase inhibitor everolimus (RAD) suppresses growth of cells derived from posttransplant lymphoproliferative disorder at allograft-protecting doses.
Journal: Transplantation 20030527
Title: Synergistic immunosuppressive effects of rosmarinic acid and rapamycin in vitro and in vivo.
Journal: Transplantation 20030527
Title: ERK and p38 inhibit the expression of 4E-BP1 repressor of translation through induction of Egr-1.
Journal: The Journal of biological chemistry 20030523
Title: Insulin induces expression of adenosine kinase gene in rat lymphocytes by signaling through the mitogen-activated protein kinase pathway.
Journal: Experimental cell research 20030515
Title: Airway anastomotic dehiscence associated with use of sirolimus immediately after lung transplantation.
Journal: Transplantation 20030515
Title: Superior T-cell suppression by rapamycin and FK506 over rapamycin and cyclosporine A because of abrogated cytotoxic T-lymphocyte induction, impaired memory responses, and persistent apoptosis.
Journal: Transplantation 20030515
Title: Sirolimus (rapamycin) monotherapy prevents graft vascular disease in nonhuman primate recipients of orthotopic aortic allografts.
Journal: Circulation 20030513
Title: Domains of Gln3p interacting with karyopherins, Ure2p, and the target of rapamycin protein.
Journal: The Journal of biological chemistry 20030509
Title: Preliminary observations regarding angiographic pattern of restenosis after rapamycin-eluting stent implantation.
Journal: Circulation 20030506
Title: Critical role for PI 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation.
Journal: Blood 20030501
Title: Estradiol rapidly activates Akt via the ErbB2 signaling pathway.
Journal: Molecular endocrinology (Baltimore, Md.) 20030501
Title: Involvement of S6 kinase and p38 mitogen activated protein kinase pathways in strain-induced alignment and proliferation of bovine aortic smooth muscle cells.
Journal: Journal of cellular physiology 20030501
Title: Transplant immunosuppressant agents and their role in autoimmune rheumatic diseases.
Journal: Current opinion in rheumatology 20030501
Title: Evaluation of coronary remodeling after sirolimus-eluting stent implantation by serial three-dimensional intravascular ultrasound.
Journal: The American journal of cardiology 20030501
Title: Pharmacokinetics of tacrolimus-based combination therapies.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030501
Title: Sirolimus as primary immunosuppression in liver transplantation is not associated with hepatic artery or wound complications.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20030501
Title: Rapamycin: friend, foe, or misunderstood?
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20030501
Title: A retrospective review of sirolimus (Rapamune) therapy in orthotopic liver transplant recipients diagnosed with chronic rejection.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20030501
Title: TOR inhibitors and cardiac allograft vasculopathy: is inhibition of intimal thickening an adequate surrogate of benefit?
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030501
Title: Rapamycin inhibits vascular remodeling in an experimental model of allograft vasculopathy and attenuates associated changes in fibrosis-associated gene expression.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030501
Title: Sirolimus: its discovery, biological properties, and mechanism of action.
Journal: Transplantation proceedings 20030501
Title: The development of immunosuppression: the rapamycin milestone.
Journal: Transplantation proceedings 20030501
Title: The Rapamune era of immunosuppression 2003: the journey from the laboratory to clinical transplantation.
Journal: Transplantation proceedings 20030501
Title: Ten years of sirolimus therapy for human renal transplantation: the University of Texas at Houston experience.
Journal: Transplantation proceedings 20030501
Title: Sirolimus therapy without calcineurin inhibitors: Necker Hospital 8-year experience.
Journal: Transplantation proceedings 20030501
Title: Bicêtre hospital experience with sirolimus-based therapy in human renal transplantation: the Sirolimus European Renal Transplant Study.
Journal: Transplantation proceedings 20030501
Title: Design of a trial comparing sirolimus plus mycophenolate mofetil versus sirolimus plus cyclosporine.
Journal: Transplantation proceedings 20030501
Title: Optimizing the long-term outcome of renal transplants: opportunities created by sirolimus.
Journal: Transplantation proceedings 20030501
Title: Use of sirolimus to facilitate cyclosporine avoidance or steroid withdrawal in kidney transplant recipients.
Journal: Transplantation proceedings 20030501
Title: How should sirolimus be used in clinical practice?
Journal: Transplantation proceedings 20030501
Title: Sirolimus experience at a Swedish transplantation center.
Journal: Transplantation proceedings 20030501
Title: Sirolimus in combination with tacrolimus or mycophenolate mofetil for minimizing acute rejection risk in renal transplant recipients--a single center experience.
Journal: Transplantation proceedings 20030501
Title: Sirolimus-based immunosuppression with reduce dose cyclosporine or tacrolimus after renal transplantation.
Journal: Transplantation proceedings 20030501
Title: Sirolimus: a single center experience in combination with calcineurin inhibitors.
Journal: Transplantation proceedings 20030501
Title: Observations on the use of sirolimus and tacrolimus in high-risk renal transplant recipients.
Journal: Transplantation proceedings 20030501
Title: Sirolimus immunotherapy: the Albany Medical Center experience.
Journal: Transplantation proceedings 20030501
Title: Sirolimus in pediatric transplant recipients.
Journal: Transplantation proceedings 20030501
Title: Reduced and standard target concentration tacrolimus with sirolimus in renal allograft recipients.
Journal: Transplantation proceedings 20030501
Title: Minimizing calcineurin inhibitor drugs in renal transplantation.
Journal: Transplantation proceedings 20030501
Title: Fixed-dose sirolimus with reduced dose calcineurin inhibitor: the University of Colorado experience.
Journal: Transplantation proceedings 20030501
Title: Kidney transplantation without calcineurin inhibitors using sirolimus.
Journal: Transplantation proceedings 20030501
Title: Sirolimus monotherapy following Campath-1H induction.
Journal: Transplantation proceedings 20030501
Title: Conversion to sirolimus in solid organ transplantation: a single-center experience.
Journal: Transplantation proceedings 20030501
Title: Clinical use of rapamycin in renal allograft recipients identifies its relevant toxicity profile and raises unsolved questions: a single-center experience.
Journal: Transplantation proceedings 20030501
Title: Sirolimus changes lipid concentrations and lipoprotein metabolism in kidney transplant recipients.
Journal: Transplantation proceedings 20030501
Title: Cardiovascular risk factors of sirolimus compared with cyclosporine: early experience from two randomized trials in renal transplantation.
Journal: Transplantation proceedings 20030501
Title: Tubular function in patients with hypokalemia induced by sirolimus after renal transplantation.
Journal: Transplantation proceedings 20030501
Title: Therapeutic monitoring of sirolimus: its contribution to optimal prescription.
Journal: Transplantation proceedings 20030501
Title: Use of rapamycin-impregnated stents in coronary arteries.
Journal: Transplantation proceedings 20030501
Title: Sirolimus therapy in cardiac transplantation.
Journal: Transplantation proceedings 20030501
Title: Safety and efficacy of sirolimus in kidney transplant patients and in patients with coronary artery disease undergoing angioplasty.
Journal: Transplantation proceedings 20030501
Title: De novo use of sirolimus in immunosuppression regimens in kidney and kidney-pancreas transplantation at the University of California, San Francisco.
Journal: Transplantation proceedings 20030501
Title: Sirolimus and islet transplants.
Journal: Transplantation proceedings 20030501
Title: Sirolimus in liver transplantation.
Journal: Transplantation proceedings 20030501
Title: Rapamycin in combination with cyclosporine or tacrolimus in liver, pancreas, and kidney transplantation.
Journal: Transplantation proceedings 20030501
Title: Ten years of sirolimus therapy in orthotopic liver transplant recipients.
Journal: Transplantation proceedings 20030501
Title: Preclinical results of sirolimus treatment in transplant models.
Journal: Transplantation proceedings 20030501
Title: Molecular actions of sirolimus: sirolimus and mTor.
Journal: Transplantation proceedings 20030501
Title: Rapamycin: signaling in vascular smooth muscle.
Journal: Transplantation proceedings 20030501
Title: Protective effect of the immunosuppressant sirolimus against aortic atherosclerosis in apo E-deficient mice.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030501
Title: Pharmacokinetics of an everolimus-cyclosporine immunosuppressive regimen over the first 6 months after kidney transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030501
Title: The effect of combined rapamycin/cyclosporine on the changes in pro-fibrotic gene expression that occur during the development of allograft vasculopathy in rats, compared with cyclosporine or rapamycin in isolation.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20030501
Title: Rapamycin throws a master switch.
Journal: Environmental health perspectives 20030501
Title: Clinical experience of sirolimus-eluting stents in patients with coronary artery disease at Bangkok Heart Institute.
Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20030501
Title: CD45RB-targeting strategies for promoting long-term allograft survival and preventingchronic allograft vasculopathy.
Journal: Transplantation 20030427
Title: Randomized trial of tacrolimus in combination with sirolimus or mycophenolate mofetil in kidney transplantation: results at 6 months.
Journal: Transplantation 20030427
Title: Health-related quality-of-life outcomes of sirolimus-treated kidney transplant patients after elimination of cyclosporine A: results of a 2-year randomized clinical trial.
Journal: Transplantation 20030427
Title: Thymoglobulin, sirolimus, and reduced-dose cyclosporine provides excellent rejection prophylaxis for pancreas transplantation.
Journal: Transplantation 20030427
Title: A phase III prospective, randomized study to evaluate concentration-controlled sirolimus (rapamune) with cyclosporine dose minimization or elimination at six months in de novo renal allograft recipients.
Journal: Transplantation 20030427
Title: Mutation in TSC2 and activation of mammalian target of rapamycin signalling pathway in renal angiomyolipoma.
Journal: Lancet (London, England) 20030419
Title: Downstream effectors of oncogenic ras in multiple myeloma cells.
Journal: Blood 20030415
Title: Inhibition of phosphatidylinositol 3-kinase and p70S6 kinase blocks osteogenic protein-1 induction of alkaline phosphatase activity in fetal rat calvaria cells.
Journal: Journal of cellular biochemistry 20030415
Title: Early withdrawal of cyclosporine A improves 1-year kidney graft structure and function in sirolimus-treated patients.
Journal: Transplantation 20030415
Title: Effect of immunosuppressants on T-cell subsets observed in vivo using carboxy-fluorescein diacetate succinimidyl ester labeling.
Journal: Transplantation 20030415
Title: Amino acid availability regulates S6K1 and protein synthesis in avian insulin-insensitive QM7 myoblasts.
Journal: FEBS letters 20030410
Title: Pilot trial of oral rapamycin for recalcitrant restenosis.
Journal: Circulation 20030408
Title: Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: progesterone receptor as a potential indicator of growth factor activity in breast cancer.
Journal: Molecular endocrinology (Baltimore, Md.) 20030401
Title: Translational control by TOR and TAP42 through dephosphorylation of eIF2alpha kinase GCN2.
Journal: Genes & development 20030401
Title: Delayed graft function and cast nephropathy associated with tacrolimus plus rapamycin use.
Journal: Journal of the American Society of Nephrology : JASN 20030401
Title: Rapamycin attenuates load-induced cardiac hypertrophy in mice.
Journal: Circulation 20030401
Title: Rapamycin mimics the incompatibility reaction in the fungus Podospora anserina.
Journal: Eukaryotic cell 20030401
Title: Sirolimus delays renal allograft recovery.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030401
Title: Sirolimus prolongs recovery from delayed graft function after cadaveric renal transplantation.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030401
Title: The addition of sirolimus to cyclosporine and steroids inhibits the anti-equine antibody response in renal transplant recipients treated with antithymocyte globulin.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030401
Title: GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR.
Journal: Molecular cell 20030401
Title: Regulated expression of erythropoietin from an AAV vector safely improves the anemia of beta-thalassemia in a mouse model.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20030401
Title: [Coronary stents].
Journal: Therapeutische Umschau. Revue therapeutique 20030401
Title: [Prevention of postangioplasty restenosis].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20030401
Title: Through the drug-eluting stent labyrinth.
Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20030401
Title: Coronary angioplasty--have we conquered restenosis?
Journal: Journal of the Indian Medical Association 20030401
Title: [Effect of rapamycin on NF-kappaB induction].
Journal: The Japanese journal of antibiotics 20030401
Title: [Influence of erythromycin and the metabolite, EM201 on IL-2 receptor signaling].
Journal: The Japanese journal of antibiotics 20030401
Title: [Suppressive effect of spiramycin on cell division].
Journal: The Japanese journal of antibiotics 20030401
Title: Branched-chain amino acids promote albumin synthesis in rat primary hepatocytes through the mTOR signal transduction system.
Journal: Biochemical and biophysical research communications 20030328
Title: Rapamycin inhibits E2F-dependent expression of minichromosome maintenance proteins in vascular smooth muscle cells.
Journal: Biochemical and biophysical research communications 20030328
Title: The impact of cyclosporine dose reduction with or without the addition of rapamycin on functional, molecular, and histological markers of chronic allograft nephropathy.
Journal: Transplantation 20030327
Title: Oral ulcers in kidney transplant recipients treated with sirolimus and mycophenolate mofetil.
Journal: Transplantation 20030327
Title: New immunosuppressive agent: expectations and controversies.
Journal: Transplantation 20030327
Title: Rapamycin inhibits proliferation of human neuroblastoma cells without suppression of MycN.
Journal: International journal of cancer 20030320
Title: Drug-eluting stents.
Journal: The Medical letter on drugs and therapeutics 20030317
Title: eIF4E/4E-BP dissociation and 4E-BP degradation in the first mitotic division of the sea urchin embryo.
Journal: Developmental biology 20030315
Title: Kidney transplantation with rabbit antithymocyte globulin and sirolimus monotherapy.
Journal: Lancet (London, England) 20030315
Title: Images in cardiovascular medicine. Sirolimus-eluting stent implanted in human coronary artery for 16 months: pathological findings.
Journal: Circulation 20030311
Title: Energetic and structural analysis of the role of tryptophan 59 in FKBP12.
Journal: Biochemistry 20030304
Title: Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process.
Journal: Nature immunology 20030301
Title: Kidney function and morphology after short-term combination therapy with cyclosporine A, tacrolimus and sirolimus in the rat.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030301
Title: Studies investigating pretransplant donor-specific blood transfusion, rapamycin, and the CD154-specific antibody IDEC-131 in a nonhuman primate model of skin allotransplantation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030301
Title: Macrophage labeling by SPIO as an early marker of allograft chronic rejection in a rat model of kidney transplantation.
Journal: Magnetic resonance in medicine 20030301
Title: Rapamycin in cardiovascular medicine.
Journal: Internal medicine journal 20030301
Title: Thrombotic micro-angiopathy with sirolimus-based immunosuppression: potentiation of calcineurin-inhibitor-induced endothelial damage?
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030301
Title: Rapamycin is an effective inhibitor of human renal cancer metastasis.
Journal: Kidney international 20030301
Title: Drug-eluting stents: potential applications for peripheral arterial occlusive disease.
Journal: Journal of vascular and interventional radiology : JVIR 20030301
Title: Comment: delayed wound healing with sirolimus after liver transplant.
Journal: The Annals of pharmacotherapy 20030301
Title: Rapamycin use and rapid withdrawal of calcineurin inhibitors in pediatric renal transplantation.
Journal: Transplantation proceedings 20030301
Title: Conversion to sirolimus after kidney and liver transplantation: indications and outcomes.
Journal: Transplantation proceedings 20030301
Title: Sirolimus in patients after liver transplantation.
Journal: Transplantation proceedings 20030301
Title: Successful retransplantation using rapamycin in a patient with previous calcineurin inhibitor-induced posterior leukoencephalopathy syndrome.
Journal: Clinical nephrology 20030301
Title: Rituximab in association with rapamycin for post-transplant lymphoproliferative disease treatment.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20030301
Title: Arterial stents as a therapeutic platform.
Journal: Surgical neurology 20030301
Title: [Role of Janus kinase/signal transducer and activator of transcription pathway in mediating mRNA expression of high mobility group box1 protein in the liver in septic rats].
Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20030301
Title: A break-even price calculation for the use of sirolimus-eluting stents in angioplasty.
Journal: Clinical therapeutics 20030301
Title: Outcomes of African-American kidney-transplant recipients treated with sirolimus, tacrolimus, and corticosteroids.
Journal: Transplantation 20030227
Title: Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling.
Journal: Oncogene 20030220
Title: Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: implications in the antiproliferative response to rapamycin.
Journal: Circulation 20030218
Title: Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression.
Journal: Blood 20030215
Title: [Sirolimus offers advantages for kidney transplant patients].
Journal: Medizinische Klinik (Munich, Germany : 1983) 20030215
Title: Evidence that cyclin D1 mediates both growth and proliferation downstream of TOR in hepatocytes.
Journal: The Journal of biological chemistry 20030207
Title: Inhibition of amino acid-mTOR signaling by a leucine derivative induces G1 arrest in Jurkat cells.
Journal: Biochemical and biophysical research communications 20030207
Title: Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein.
Journal: Oncogene 20030206
Title: In-stent stenosis: pathology and implications for the development of drug eluting stents.
Journal: Heart (British Cardiac Society) 20030201
Title: Sirolimus and lymphocele formation after kidney transplantation: an immunosuppressive medication as co-factor for a surgical problem?
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030201
Title: Phenytoin decreases the blood concentrations of sirolimus in a liver transplant recipient: a case report.
Journal: Therapeutic drug monitoring 20030201
Title: Sirolimus monotherapy in nephrotoxicity due to calcineurin inhibitors in liver transplant recipients.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20030201
Title: Combination of caspofungin with inhibitors of the calcineurin pathway attenuates growth in vitro in Aspergillus species.
Journal: The Journal of antimicrobial chemotherapy 20030201
Title: Insulin-like growth factor-I and the cytokines IL-3 and IL-4 promote survival of progenitor myeloid cells by different mechanisms.
Journal: Journal of neuroimmunology 20030201
Title: Early experience with sirolimus in lung transplant recipients with chronic allograft rejection.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030201
Title: Interstitial pneumonitis associated with sirolimus: a dilemma for lung transplantation.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030201
Title: [Effects of three different immunosuppressive drugs on SD rat islet cell viability].
Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030201
Title: A new era in the treatment of coronary disease?
Journal: European heart journal 20030201
Title: Sirolimus antirejection therapy for renal transplantation with cyclosporine-based immunosuppression: case reports.
Journal: Transplantation proceedings 20030201
Title: Linear correlation between sirolimus and cyclosporine trough levels in renal transplant patients.
Journal: Transplantation proceedings 20030201
Title: Rapamycin induces Smad activity in prostate cancer cell lines.
Journal: Urological research 20030201
Title: Sirolimus may promote thrombotic microangiopathy.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030201
Title: Rapamycin as rescue therapy in a patient supported by biventricular assist device to heart transplantation with consecutive ongoing rejection.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030201
Title: Clinical development of an everolimus pediatric formulation: relative bioavailability, food effect, and steady-state pharmacokinetics.
Journal: Journal of clinical pharmacology 20030201
Title: Teaching old drugs new tricks: reincarnating immunosuppressants as antifungal drugs.
Journal: Current opinion in investigational drugs (London, England : 2000) 20030201
Title: Rapamycin reduces neointima formation during vascular injury.
Journal: VASA. Zeitschrift fur Gefasskrankheiten 20030201
Title: Effect of sirolimus in combination with low-dose cyclosporine and steroids on acute renal allograft rejection.
Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20030201
Title: [Regulatory mechanisms and the influence of immunosuppressive drugs on liver regeneration after partial hepatectomy].
Journal: Polskie Archiwum Medycyny Wewnetrznej 20030201
Title: Two-year angiographic and intravascular ultrasound follow-up after implantation of sirolimus-eluting stents in human coronary arteries.
Journal: Circulation 20030128
Title: Drug-eluting stents in vascular intervention.
Journal: Lancet (London, England) 20030118
Title: In vivo and in vitro effects of SAR 943, a rapamycin analogue, on airway inflammation and remodeling.
Journal: American journal of respiratory and critical care medicine 20030115
Title: Modeling individual variation in biomarker response to combination immunosuppression with stimulated lymphocyte responses-potential clinical implications.
Journal: Journal of immunological methods 20030115
Title: Sirolimus-eluting stent for treatment of complex in-stent restenosis: the first clinical experience.
Journal: Journal of the American College of Cardiology 20030115
Title: Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways.
Journal: Cancer research 20030115
Title: Combination therapy of mycophenolate mofetil and rapamycin in prevention of chronic renal allograft rejection in the rat.
Journal: Transplantation 20030115
Title: Improved freedom from rejection after a loading dose of sirolimus.
Journal: Transplantation 20030115
Title: Rapamycin impairs antigen uptake of human dendritic cells.
Journal: Transplantation 20030115
Title: Severe acute renal failure after exposure to sirolimus-tacrolimus in two living donor kidney recipients.
Journal: Transplantation 20030115
Title: Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases.
Journal: Biochemistry 20030114
Title: Sirolimus-eluting stent for the treatment of in-stent restenosis: a quantitative coronary angiography and three-dimensional intravascular ultrasound study.
Journal: Circulation 20030107
Title: Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin.
Journal: Blood 20030101
Title: Modulation of the electrophoretic mobility of the linker for activation of T cells (LAT) by the calcineurin inhibitors CsA and FK506: LAT is a potential substrate for PKC and calcineurin signaling pathways.
Journal: Cellular signalling 20030101
Title: Creating polyketide diversity through genetic engineering.
Journal: Frontiers in bioscience : a journal and virtual library 20030101
Title: Effects of FK506 on [Ca2+]i differ in mouse and rabbit ventricular myocytes.
Journal: The Journal of pharmacology and experimental therapeutics 20030101
Title: Differential regulation of lipogenesis and leptin production by independent signaling pathways and rosiglitazone during human adipocyte differentiation.
Journal: Diabetes 20030101
Title: The product of the UTH1 gene, required for Bax-induced cell death in yeast, is involved in the response to rapamycin.
Journal: Molecular microbiology 20030101
Title: Drug-eluting stents to prevent reblockage of coronary arteries.
Journal: The Journal of cardiovascular nursing 20030101
Title: Tacrolimus and sirolimus decrease oxidative phosphorylation of isolated rat kidney mitochondria.
Journal: British journal of pharmacology 20030101
Title: [Opening of ATP-sensitive potassium channel attenuates cardiac remodeling induced by chronic inhibition of nitric oxide synthesis].
Journal: Journal of cardiology 20030101
Title: Metabolic screening of mammalian cell cultures using well-plates.
Journal: Biotechnology progress 20030101
Title: Steroid-refractory graft-vs.-host disease: past, present and future.
Journal: Pediatric transplantation 20030101
Title: [Edema of the eyelids caused by sirolimus in renal transplant recipients].
Journal: Annales de dermatologie et de venereologie 20030101
Title: Sirolimus eluting stent: a new era in interventional cardiology?
Journal: Current pharmaceutical design 20030101
Title: Synergistic effect of vincristine with tacrolimus or sirolimus in prevention of acute heart allograft rejection in the rat.
Journal: Microsurgery 20030101
Title: [Epstein Barr viral load monitoring in mononuclear lymphocytes and serum of renal transplant recipients using a quantitative PCR protocol].
Journal: Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20030101
Title: Morphological and biochemical effects of immunosuppressive drugs in a capillary tube assay for endothelial dysfunction.
Journal: Clinical transplantation 20030101
Title: A pilot protocol of a calcineurin-inhibitor free regimen for kidney transplant recipients of marginal donor kidneys or with delayed graft function.
Journal: Clinical transplantation 20030101
Title: [Therapeutic drug monitoring of mycophenolate mofetil, sirolimus and cyclosporine at C2].
Journal: Annales de biologie clinique 20030101
Title: c-Myc oncoprotein: cell cycle-related events and new therapeutic challenges in cancer and cardiovascular diseases.
Journal: Cell cycle (Georgetown, Tex.) 20030101
Title: A bicyclic monoterpene diol and UVB stimulate BRCA1 phosphorylation in human keratinocytes.
Journal: Photochemistry and photobiology 20030101
Title: Structures of immunophilins and their ligand complexes.
Journal: Current topics in medicinal chemistry 20030101
Title: Rapamycins: mechanism of action and cellular resistance.
Journal: Cancer biology & therapy 20030101
Title: Oral rapamycin inhibits growth of atherosclerotic plaque in apoE knock-out mice.
Journal: Cardiovascular radiation medicine 20030101
Title: [Drug releasing stents].
Journal: Archivos de cardiologia de Mexico 20030101
Title: Influence of immunosuppressive drugs on dendritic cells.
Journal: Transplant immunology 20030101
Title: New regimen for kidney transplants.
Journal: FDA consumer 20030101
Title: New drug-device combination helps keep arteries open.
Journal: FDA consumer 20030101
Title: The molecular target of rapamycin (mTOR) as a therapeutic target against cancer.
Journal: Cancer biology & therapy 20030101
Title: Synergistic effects of RAD and Neoral in inhibition of host-vs.-graft and graft-vs.-host immune responses in rat small-bowel transplantation.
Journal: Microsurgery 20030101
Title: Renal transplantation: basic concepts and evolution of therapy.
Journal: Journal of clinical apheresis 20030101
Title: [Recent trend in interventional cardiology--drug-containing stents].
Journal: Terapevticheskii arkhiv 20030101
Title: Role of calcineurin in calcium-mediated hypoxic injury to white matter.
Journal: The spine journal : official journal of the North American Spine Society 20030101
Title: Cap-dependent translation and control of the cell cycle.
Journal: Progress in cell cycle research 20030101
Title: Islet of Langerhans transplantation for the treatment of type 1 diabetes.
Journal: Swiss surgery = Schweizer Chirurgie = Chirurgie suisse = Chirurgia svizzera 20030101
Title: [Side effects and toxicity of immunosuppressive agents].
Journal: Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20030101
Title: Inflammation and restenosis: implications for therapy.
Journal: Annals of medicine 20030101
Title: Insulin-like growth factor binding protein-6 and CCI-779, an ester analogue of rapamycin, additively inhibit rhabdomyosarcoma growth.
Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20030101
Title: The sirolimus-eluting stent: a review of its use in the treatment of coronary artery disease.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101
Title: Intracoronary brachytherapy following drug-eluting stent failure. It's still not time to hang up the spikes!
Journal: Cardiovascular radiation medicine 20030101
Title: Kidney and pancreas transplantation at Wake Forest University Baptist Medical Center.
Journal: Clinical transplants 20030101
Title: [Rapamycin: from the laboratory to the treatment of patients' arteries].
Journal: Revista espanola de cardiologia 20030101
Title: Localisation and regulation of the eIF4E-binding protein 4E-BP3.
Journal: FEBS letters 20021218
Title: Improved renal function in sirolimus-treated renal transplant patients after early cyclosporine elimination.
Journal: Transplantation 20021215
Title: Inhibition of the mammalian target of rapamycin sensitizes U87 xenografts to fractionated radiation therapy.
Journal: Cancer research 20021215
Title: Drug eluting coronary stents.
Journal: BMJ (Clinical research ed.) 20021207
Title: Effects of immunosuppressants, calcineurin inhibition, and blockade of endoplasmic reticulum calcium channels on free fatty acid efflux from the ischemic/reperfused rat cerebral cortex.
Journal: Brain research 20021206
Title: Influence of the new immunosuppressive combinations on arterial hypertension after renal transplantation.
Journal: Kidney international. Supplement 20021201
Title: Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells.
Journal: Molecular and cellular biology 20021201
Title: Clonal anergy is maintained independently of T cell proliferation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20021201
Title: Programmed death-1 targeting can promote allograft survival.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20021201
Title: Measurement of whole blood sirolimus by an HPLC assay using solid-phase extraction and UV detection.
Journal: Therapeutic drug monitoring 20021201
Title: Inhibition of autophagy in mitotic animal cells.
Journal: Traffic (Copenhagen, Denmark) 20021201
Title: Differential Effect of sirolimus vs prednisolone in the treatment of sclerosing encapsulating peritonitis.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20021201
Title: Review of the proliferation inhibitor everolimus.
Journal: Expert opinion on investigational drugs 20021201
Title: Histopathological study of intrahepatic islets transplanted in the nonhuman primate model using edmonton protocol immunosuppression.
Journal: The Journal of clinical endocrinology and metabolism 20021201
Title: Sirolimus: new preparation. No tangible advance in renal transplantation.
Journal: Prescrire international 20021201
Title: Evaluation for synergistic suppression of T cell responses to minor histocompatibility antigens by chloroquine in combination with tacrolimus and a rapamycin derivative, SDZ-RAD.
Journal: Bone marrow transplantation 20021201
Title: Sirolimus-eluting coronary stents.
Journal: Journal of interventional cardiology 20021201
Title: T-stenting with drug-eluting stents for the treatment of bifurcation in-stent restenosis.
Journal: Journal of interventional cardiology 20021201
Title: Studies of cargo delivery to the vacuole mediated by autophagosomes in Saccharomyces cerevisiae.
Journal: Developmental cell 20021201
Title: Effect of sirolimus on ischemia/reperfusion injury in transgenic hypertensive rat.
Journal: Transplantation proceedings 20021201
Title: Basiliximab-sirolimus-prednisone induction regimen followed by delayed low-dose cyclosporine in renal transplant recipients of living donors.
Journal: Transplantation proceedings 20021201
Title: Sirolimus rescue treatment in calcineurin-inhibitor nephrotoxicity after kidney transplantation.
Journal: Transplantation proceedings 20021201
Title: Immunosuppression with sirolimus/tacrolimus combination in pancreas transplantation: 1-year results.
Journal: Transplantation proceedings 20021201
Title: Interaction of immunosuppressive agents rapamycin and its analogue SDZ-RAD with endothelial P-gp.
Journal: Transplantation proceedings 20021201
Title: Regulation of subtelomeric silencing during stress response.
Journal: Molecular cell 20021201
Title: Maf1 is an essential mediator of diverse signals that repress RNA polymerase III transcription.
Journal: Molecular cell 20021201
Title: New treatment for clogged coronary arteries.
Journal: Mayo Clinic health letter (English ed.) 20021201
Title: [To further improve transplantation results].
Journal: Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20021201
Title: Fluconazole-sirolimus drug interaction.
Journal: Transplantation 20021127
Title: Images in Cardiovascular Medicine. True three-dimensional reconstructed images showing lumen enlargement after sirolimus-eluting stent implantation.
Journal: Circulation 20021126
Title: Kidney transplantation with rabbit antithymocyte globulin induction and sirolimus monotherapy.
Journal: Lancet (London, England) 20021123
Title: Synthetic lethality: killing cancer with cancer.
Journal: Journal of the National Cancer Institute 20021120
Title: Nuclear translocation of insulin receptor substrate-1 by oncogenes and Igf-I. Effect on ribosomal RNA synthesis.
Journal: The Journal of biological chemistry 20021115
Title: BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin.
Journal: Blood 20021115
Title: Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast.
Journal: The Journal of biological chemistry 20021108
Title: The immunosuppressant rapamycin, alone or with transforming growth factor-beta, enhances osteoclast differentiation of RAW264.7 monocyte-macrophage cells in the presence of RANK-ligand.
Journal: Calcified tissue international 20021101
Title: Different mechanisms are utilized by HIV-1 Nef and staphylococcal enterotoxin A to control and regulate interleukin-10 production.
Journal: Immunology letters 20021101
Title: The immunosuppressant rapamycin represses human immunodeficiency virus type 1 replication.
Journal: Antimicrobial agents and chemotherapy 20021101
Title: Combined effects of calcineurin inhibitors or sirolimus with anti-CD40L mAb on alloengraftment under nonmyeloablative conditions.
Journal: Blood 20021101
Title: Effects of the combination of rapamycin with tacrolimus or cyclosporin on experimental intimal hyperplasia.
Journal: The British journal of surgery 20021101
Title: Sirolimus (Rapamune) in renal transplantation.
Journal: Current opinion in nephrology and hypertension 20021101
Title: Therapeutic drug monitoring of immunosuppressive drugs in kidney transplantation.
Journal: Current opinion in nephrology and hypertension 20021101
Title: Drug-eluting stent: the 'magic bullet' for prevention of restenosis?
Journal: Basic research in cardiology 20021101
Title: Fate of side branches after coronary arterial sirolimus-eluting stent implantation.
Journal: The American journal of cardiology 20021101
Title: New insights into the interactions between T-cell costimulatory blockade and conventional immunosuppressive drugs.
Journal: Annals of surgery 20021101
Title: Ras/Erk signaling is essential for activation of protein synthesis by Gq protein-coupled receptor agonists in adult cardiomyocytes.
Journal: Circulation research 20021101
Title: Inhibitors of mTOR reverse doxorubicin resistance conferred by PTEN status in prostate cancer cells.
Journal: Cancer research 20021101
Title: Ca(2+)-dependent interaction between FKBP12 and calcineurin regulates activity of the Ca(2+) release channel in skeletal muscle.
Journal: Biophysical journal 20021101
Title: Sirolimus and FTY720: new approaches to transplant immunosuppression.
Journal: Transplantation proceedings 20021101
Title: Effect of rapamycin and prednisolone in differentiated THP-1 and U937 cells.
Journal: Transplantation proceedings 20021101
Title: Pharmacodynamics of sirolimus and cyclosporine combination therapy.
Journal: Transplantation proceedings 20021101
Title: Sirolimus attenuates the expression of metalloproteinase-2 and -9 and inhibits intimal hyperplasia following balloon angioplasty.
Journal: Transplantation proceedings 20021101
Title: Rituximab and rapamycin for posttransplant lymphoproliferative disease treatment: report of three cases.
Journal: Transplantation proceedings 20021101
Title: Flow cytometric detection of intracellular IL-12 release: in vitro effect of widely used immunosuppressants.
Journal: International immunopharmacology 20021101
Title: [Treatment of diabetes mellitus in patients after renal transplantation].
Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20021101
Title: [Effect of immunosuppressive treatment on diurnal profile of blood pressure].
Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20021101
Title: Systemic drug therapy for restenosis: 'déjà vu all over again'.
Journal: Circulation 20021029
Title: Oral everolimus inhibits in-stent neointimal growth.
Journal: Circulation 20021029
Title: Kidney transplantation without calcineurin inhibitor drugs: a prospective, randomized trial of sirolimus versus cyclosporine.
Journal: Transplantation 20021027
Title: Sirolimus-eluting coronary stents.
Journal: The New England journal of medicine 20021017
Title: Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors.
Journal: Cancer research 20021015
Title: The group I metabotropic glutamate receptor agonist (S)-3,5-dihydroxyphenylglycine induces a novel form of depotentiation in the CA1 region of the hippocampus.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20021015
Title: Oral efficacy of the new immunomodulator FTY720 in cynomolgus monkey kidney allotransplantation, given alone or in combination with cyclosporine or RAD.
Journal: Transplantation 20021015
Title: Multiple signalling pathways mediate insulin-stimulated gene expression in 3T3-L1 adipocytes.
Journal: Biochimica et biophysica acta 20021011
Title: Angiographic findings of the multicenter Randomized Study With the Sirolimus-Eluting Bx Velocity Balloon-Expandable Stent (RAVEL): sirolimus-eluting stents inhibit restenosis irrespective of the vessel size.
Journal: Circulation 20021008
Title: Phosphorylation-dependent interaction of the asialoglycoprotein receptor with molecular chaperones.
Journal: The Journal of biological chemistry 20021004
Title: Identification of TOR signaling complexes: more TORC for the cell growth engine.
Journal: Cell 20021004
Title: Proliferation of IL-6-independent multiple myeloma does not require the activity of extracellular signal-regulated kinases (ERK1/2).
Journal: Journal of cellular physiology 20021001
Title: Activation of multiple signaling modules is critical in angiotensin IV-induced lung endothelial cell proliferation.
Journal: American journal of physiology. Lung cellular and molecular physiology 20021001
Title: The FKBP12-rapamycin-associated protein (FRAP) is a CLIP-170 kinase.
Journal: EMBO reports 20021001
Title: Cyclosporin-A differentially affects apoptosis during in vivo rat thymocyte maturation.
Journal: Scandinavian journal of immunology 20021001
Title: A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling.
Journal: Biochemical pharmacology 20021001
Title: Sirolimus oral absorption in rats is increased by ketoconazole but is not affected by D-alpha-tocopheryl poly(ethylene glycol 1000) succinate.
Journal: The Journal of pharmacology and experimental therapeutics 20021001
Title: Hepatocyte growth factor induced human trophoblast motility involves phosphatidylinositol-3-kinase, mitogen-activated protein kinase, and inducible nitric oxide synthase.
Journal: Experimental cell research 20021001
Title: Contrasting impacts of immunosuppressive agents (rapamycin, FK506, cyclosporin A, and dexamethasone) on bidirectional dendritic cell-T cell interaction during antigen presentation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20021001
Title: Impact of immunosuppressive therapy on recurrence of hepatitis C.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20021001
Title: Sirolimus eluting stent in the treatment of atherosclerosis coronary artery disease.
Journal: Minerva cardioangiologica 20021001
Title: Drug-eluting stents.
Journal: Minerva cardioangiologica 20021001
Title: Drug-eluting stent: the emerging technique for the prevention of restenosis.
Journal: Minerva cardioangiologica 20021001
Title: Drug-eluting stents: clinical experiences and perspectives.
Journal: Minerva cardioangiologica 20021001
Title: Drug eluting stents: managing coronary artery stenosis following PTCA.
Journal: Issues in emerging health technologies 20021001
Title: Cardiovascular toxicities of immunosuppressive agents.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20021001
Title: Constitutive activation of p70S6k in cancer cells.
Journal: Archives of pharmacal research 20021001
Title: Dimerizer-regulated gene expression.
Journal: Current opinion in biotechnology 20021001
Title: Calcineurin inhibitors and sirolimus: mechanisms of action and applications in dermatology.
Journal: Clinical and experimental dermatology 20021001
Title: Sirolimus-eluting stents: the novel application of basic science to coronary artery disease.
Journal: Irish medical journal 20021001
Title: The '0%' restenosis study.
Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20021001
Title: Clinical development of mammalian target of rapamycin inhibitors.
Journal: Hematology/oncology clinics of North America 20021001
Title: Incidence, therapy, and consequences of lymphocele after sirolimus-cyclosporine-prednisone immunosuppression in renal transplant recipients.
Journal: Transplantation 20020927
Title: Artificial mammalian gene regulation networks-novel approaches for gene therapy and bioengineering.
Journal: Journal of biotechnology 20020925
Title: Persistent inhibition of neointimal hyperplasia after sirolimus-eluting stent implantation: long-term (up to 2 years) clinical, angiographic, and intravascular ultrasound follow-up.
Journal: Circulation 20020924
Title: Convergence of the target of rapamycin and the Snf1 protein kinase pathways in the regulation of the subcellular localization of Msn2, a transcriptional activator of STRE (Stress Response Element)-regulated genes.
Journal: The Journal of biological chemistry 20020920
Title: Sirolimus-eluting stents for the treatment of obstructive superficial femoral artery disease: six-month results.
Journal: Circulation 20020917
Title: Sirolimus-induced leukocytoclastic vasculitis.
Journal: Transplantation 20020915
Title: American Chemical Society meeting. Chemists search for solutions.
Journal: Science (New York, N.Y.) 20020913
Title: TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation.
Journal: Current biology : CB 20020903
Title: Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling.
Journal: Nature cell biology 20020901
Title: Role of the p70 S6 kinase cascade in neutrophilic differentiation and proliferation of HL-60 cells-a study of transferrin receptor-positive and -negative cells obtained from dimethyl sulfoxide- or retinoic acid-treated HL-60 cells.
Journal: Archives of biochemistry and biophysics 20020901
Title: Effect of insulin-like growth factor II on protecting myoblast cells against cisplatin-induced apoptosis through p70 S6 kinase pathway.
Journal: Neoplasia (New York, N.Y.) 20020901
Title: Mycophenolic acid inhibits IL-2-dependent T cell proliferation, but not IL-2-dependent survival and sensitization to apoptosis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020901
Title: Delayed wound healing with sirolimus after liver transplant.
Journal: The Annals of pharmacotherapy 20020901
Title: Nelfinavir, a protease inhibitor, increases sirolimus levels in a liver transplantation patient: a case report.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20020901
Title: No delayed restenosis at 18 months after implantation of sirolimus-eluting stent.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20020901
Title: Drug-eluting stents for the prevention of restenosis: Standing the test of time.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20020901
Title: Enhanced sensitivity of multiple myeloma cells containing PTEN mutations to CCI-779.
Journal: Cancer research 20020901
Title: Comparative study of cyclosporine and tacrolimus vs newer immunosuppressants mycophenolate mofetil and rapamycin on coronary endothelial function.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20020901
Title: Everolimus (Certican) in combination with neoral in pediatric renal transplant recipients: interim analysis after 3 months.
Journal: Transplantation proceedings 20020901
Title: Long-term pharmacokinetics of the metabolites of everolimus and cyclosporine in renal transplant recipients.
Journal: Transplantation proceedings 20020901
Title: Sirolimus in late acute OKT3-resistant and/or steroid-resistant rejection after simultaneous pancreas and kidney transplantation.
Journal: Transplantation proceedings 20020901
Title: Onset of liver regeneration after subtotal resection is inhibited by the use of new immunosuppressive drugs.
Journal: Transplantation proceedings 20020901
Title: Can we prevent in-stent restenosis?
Journal: Current opinion in cardiology 20020901
Title: Care of the kidney transplant recipient. Vigilant monitoring creates the best outcome.
Journal: Postgraduate medicine 20020901
Title: [Drug-eluding stents: bis repetita?].
Journal: Archives des maladies du coeur et des vaisseaux 20020901
Title: Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control.
Journal: Molecular cell 20020901
Title: Goosebumps.
Journal: Lancet (London, England) 20020831
Title: Regulation of ribosomal S6 kinase 2 by mammalian target of rapamycin.
Journal: The Journal of biological chemistry 20020830
Title: Immunologic mechanisms in tolerance produced in mice with nonradiation-based lymphoablation and donor-specific bone marrow.
Journal: Transplantation 20020827
Title: Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM).
Journal: The Journal of biological chemistry 20020823
Title: Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells.
Journal: Oncogene 20020815
Title: Intravascular ultrasound findings in the multicenter, randomized, double-blind RAVEL (RAndomized study with the sirolimus-eluting VElocity balloon-expandable stent in the treatment of patients with de novo native coronary artery Lesions) trial.
Journal: Circulation 20020813
Title: Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway.
Journal: The Journal of biological chemistry 20020802
Title: Effect of immunosuppressive agents on glucocorticoid receptor function in A6 cells.
Journal: American journal of physiology. Renal physiology 20020801
Title: Rapamycin inhibits macropinocytosis and mannose receptor-mediated endocytosis by bone marrow-derived dendritic cells.
Journal: Blood 20020801
Title: Sirolimus-based immunosuppression for transplant-associated thrombotic microangiopathy.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020801
Title: Sirolimus lowers myeloperoxidase and p-ANCA titers in a pediatric patient before kidney transplantation.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20020801
Title: Signalling pathways and combinatory effects of insulin and amino acids in isolated rat hepatocytes.
Journal: European journal of biochemistry 20020801
Title: Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes.
Journal: European journal of biochemistry 20020801
Title: Transmitting the signal of excess nitrogen in Saccharomyces cerevisiae from the Tor proteins to the GATA factors: connecting the dots.
Journal: FEMS microbiology reviews 20020801
Title: Multiple ion isolation applications in FT-ICR MS: exact-mass MSn internal calibration and purification/interrogation of protein-drug complexes.
Journal: Analytical chemistry 20020801
Title: Rapamycin blocks the generation of regulatory T cells facilitated by posttransplant infusion of donor T cells through increasing the apoptosis of thymic CD4(+)CD25(+) cells.
Journal: Transplantation proceedings 20020801
Title: Sirolimus inhibits growth of human hepatoma cells in contrast to tacrolimus which promotes cell growth.
Journal: Transplantation proceedings 20020801
Title: Inhibition of IL-12 signaling Stat4/IFN-gamma pathway by rapamycin is associated with impaired dendritic [correction of dendritc] cell function.
Journal: Transplantation proceedings 20020801
Title: Influence of immunosuppressive drugs on intestinal epithelial transport function.
Journal: Transplantation proceedings 20020801
Title: Effect of rapamycin in combination with calcineurin inhibitors, FK506 and cyclosporin, following arterial injury.
Journal: Transplantation proceedings 20020801
Title: Sirolimus-based immunosuppressive [correction of immunosuppresive] protocol for calcineurin sparing in liver transplantation.
Journal: Transplantation proceedings 20020801
Title: Randomized trial of three different immunosuppressive regimens to prevent chronic renal allograft rejection.
Journal: Transplantation proceedings 20020801
Title: Early experience using calcineurin-free protocol in recipients of high-risk cadaver renal transplants.
Journal: Transplantation proceedings 20020801
Title: Medium-term outcome using sirolimus-tacrolimus combination in adult renal transplant recipients.
Journal: Transplantation proceedings 20020801
Title: A pilot trial of tacrolimus, sirolimus, and steroids in renal transplant recipients.
Journal: Transplantation proceedings 20020801
Title: A retrospective analysis of a sirolimus/prograf regimen for the prevention of acute rejection in recipients of primary mismatched renal allografts.
Journal: Transplantation proceedings 20020801
Title: Sirolimus-based steroid-free maintenance immunosuppression.
Journal: Transplantation proceedings 20020801
Title: Increased frequency of lymphoceles under treatment with sirolimus following renal transplantation: a single center experience.
Journal: Transplantation proceedings 20020801
Title: Sirolimus and tacrolimus in clinical cardiac transplantation.
Journal: Transplantation proceedings 20020801
Title: Can acute rejection be prevented in SPK transplantation?
Journal: Transplantation proceedings 20020801
Title: Rejection-free protocol using sirolimus-tacrolimus combination for pediatric renal transplant recipients.
Journal: Transplantation proceedings 20020801
Title: Improved lipid profile and blood sugar control in pediatric renal transplant recipients using sirolimus-tacrolimus combination.
Journal: Transplantation proceedings 20020801
Title: Pharmacodynamics of sirolimus in transplanted children receiving tacrolimus.
Journal: Transplantation proceedings 20020801
Title: Preliminary immunosuppression withdrawal strategies with sirolimus in children with liver transplants.
Journal: Transplantation proceedings 20020801
Title: Nutrient-hormone interaction in the ovine liver: methionine supply selectively modulates growth hormone-induced IGF-I gene expression.
Journal: The Journal of endocrinology 20020801
Title: Effects of sirolimus on plasma lipids, lipoprotein levels, and fatty acid metabolism in renal transplant patients.
Journal: Journal of lipid research 20020801
Title: Loss of ypk1 function causes rapamycin sensitivity, inhibition of translation initiation and synthetic lethality in 14-3-3-deficient yeast.
Journal: Genetics 20020801
Title: CCI-779 Wyeth.
Journal: Current opinion in investigational drugs (London, England : 2000) 20020801
Title: The neuronal choline transporter CHT1 is regulated by immunosuppressor-sensitive pathways.
Journal: Journal of neurochemistry 20020801
Title: Outcomes of African American kidney transplant recipients treated with sirolimus, tacrolimus, and corticosteroids.
Journal: Transplantation 20020727
Title: VIIa/tissue factor interaction results in a tissue factor cytoplasmic domain-independent activation of protein synthesis, p70, and p90 S6 kinase phosphorylation.
Journal: The Journal of biological chemistry 20020726
Title: mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery.
Journal: Cell 20020726
Title: Assessment of sirolimus concentrations in whole blood by high-performance liquid chromatography with ultraviolet detection.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020715
Title: The impact of novel immunosuppressive agents on infections in organ transplant recipients and the interactions of these agents with antimicrobials.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020701
Title: Termination of cardiac Ca(2+) sparks: an investigative mathematical model of calcium-induced calcium release.
Journal: Biophysical journal 20020701
Title: Constitutive and regulated expression of processed insulin following in vivo hepatic gene transfer.
Journal: Gene therapy 20020701
Title: Regulation of endogenous gene expression with a small-molecule dimerizer.
Journal: Nature biotechnology 20020701
Title: Sirolimus steady-state trough concentrations are not affected by bolus methylprednisolone therapy in renal allograft recipients.
Journal: British journal of clinical pharmacology 20020701
Title: Effects of sirolimus on lipids in renal allograft recipients: an analysis using the Framingham risk model.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20020701
Title: Mechanisms involved in responses to the poroxisome proliferator WY-14,643 on gap junctional intercellular communication in V79 hamster fibroblasts.
Journal: Toxicology and applied pharmacology 20020701
Title: Successful treatment of tacrolimus-associated thrombotic microangiopathy with sirolimus conversion and plasma exchange.
Journal: Clinical nephrology 20020701
Title: An unexpected inhibitory effect of rapamycin against germination of spores of Bacillus brevis strain Nagano.
Journal: The Journal of antibiotics 20020701
Title: What is 'the matter' with restenosis in 2002?
Journal: Circulation 20020625
Title: c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells.
Journal: The Journal of biological chemistry 20020621
Title: Global and specific translational control by rapamycin in T cells uncovered by microarrays and proteomics.
Journal: The Journal of biological chemistry 20020621
Title: Effect of rapamycin on the cyclosporin A-resistant CD28-mediated costimulatory pathway.
Journal: Blood 20020615
Title: Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E.
Journal: Genes & development 20020615
Title: Mks1p is required for negative regulation of retrograde gene expression in Saccharomyces cerevisiae but does not affect nitrogen catabolite repression-sensitive gene expression.
Journal: The Journal of biological chemistry 20020607
Title: Sirolimus-eluting coronary stents.
Journal: The New England journal of medicine 20020606
Title: A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization.
Journal: The New England journal of medicine 20020606
Title: Quantification and stability of everolimus (SDZ RAD) in human blood by high-performance liquid chromatography-electrospray tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020605
Title: Insulinlike growth factor-I signaling in multiple myeloma: downstream elements, functional correlates, and pathway cross-talk.
Journal: Blood 20020601
Title: A clinical pharmacokinetic study of tacrolimus and sirolimus combination immunosuppression comparing simultaneous to separated administration.
Journal: Therapeutic drug monitoring 20020601
Title: Effect of rifampin on apparent clearance of everolimus.
Journal: The Annals of pharmacotherapy 20020601
Title: Rapid liquid chromatography-tandem mass spectrometry routine method for simultaneous determination of sirolimus, everolimus, tacrolimus, and cyclosporin A in whole blood.
Journal: Clinical chemistry 20020601
Title: In vitro evaluation of motilin agonism by macrolide immunosuppressive drugs.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020601
Title: Sirolimus tolerability in a kidney transplant recipient with acute intermittent porphyria.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020601
Title: Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020601
Title: The effects of rapamycin in murine peripheral nerve isografts and allografts.
Journal: Plastic and reconstructive surgery 20020601
Title: Rapamycin induces binding activity to the terminal oligopyrimidine tract of ribosomal protein mRNA in rats.
Journal: Archives of biochemistry and biophysics 20020601
Title: Sirolimus/cyclosporine/tacrolimus interactions on bile flow and biliary excretion of immunosuppressants in a subchronic bile fistula rat model.
Journal: British journal of pharmacology 20020601
Title: Implication of alpha4 phosphoprotein and the rapamycin-sensitive mammalian target-of-rapamycin pathway in prolactin receptor signalling.
Journal: The Journal of endocrinology 20020601
Title: Combined immunosuppression with cyclosporine, rapamycin, and mycophenolate mofetil controls rejection with minimal nutritional impact in experimental small intestinal transplantation.
Journal: Transplantation proceedings 20020601
Title: Influence of a novel rapamycin analogon SDZ RAD on endothelial tissue factor and adhesion molecule expression.
Journal: Transplantation proceedings 20020601
Title: Prolongation of fully allogeneic skin graft survival in the rat by combined administration of costimulatory blockade and sirolimus.
Journal: Transplantation proceedings 20020601
Title: Role of immunosuppressive drugs in the development of tissue-invasive cytomegalovirus infection in renal transplant recipients.
Journal: Transplantation proceedings 20020601
Title: New developments in immunosuppressive therapy in renal transplantation.
Journal: Expert opinion on biological therapy 20020601
Title: Rapamycin and T cell costimulatory blockade as post-transplant treatment promote fully MHC-mismatched allogeneic bone marrow engraftment under irradiation-free conditioning therapy.
Journal: Bone marrow transplantation 20020601
Title: The rapamycin analogue SDZ RAD attenuates bleomycin-induced pulmonary fibrosis in rats.
Journal: The European respiratory journal 20020601
Title: Coated stents: a novel approach to prevent in-stent restenosis.
Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20020601
Title: Modern strategies to prevent coronary restenosis.
Journal: Italian heart journal : official journal of the Italian Federation of Cardiology 20020601
Title: Control of proteolysis by norepinephrine and insulin in brown adipocytes: role of ATP, phosphatidylinositol 3-kinase, and p70 S6K.
Journal: Canadian journal of physiology and pharmacology 20020601
Title: [Metabolic modifications related to immunosuppressive drugs].
Journal: Revue medicale de Bruxelles 20020601
Title: Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site.
Journal: The Journal of biological chemistry 20020531
Title: Intestinal transplantation before and after the introduction of sirolimus.
Journal: Transplantation 20020527
Title: Rapamycin blocks tumor progression: unlinking immunosuppression from antitumor efficacy.
Journal: Transplantation 20020527
Title: [Consistent success with coated stents. Coronary arteries stay open longer].
Journal: MMW Fortschritte der Medizin 20020523
Title: Ro 31-6045, the inactive analogue of the protein kinase C inhibitor Ro 31-8220, blocks in vivo activation of p70(s6k)/p85(s6k): implications for the analysis of S6K signalling.
Journal: FEBS letters 20020522
Title: Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load.
Journal: The Journal of biological chemistry 20020517
Title: Myogenic differentiation is dependent on both the kinase function and the N-terminal sequence of mammalian target of rapamycin.
Journal: The Journal of biological chemistry 20020510
Title: Rapamycin partially prevents insulin resistance induced by chronic insulin treatment.
Journal: Biochemical and biophysical research communications 20020510
Title: Images in cardiovascular medicine. Left main rapamycin-coated stent: invasive versus noninvasive angiographic follow-up.
Journal: Circulation 20020507
Title: Signal pathways involved in activation of p70S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6.
Journal: The Journal of biological chemistry 20020503
Title: Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy.
Journal: Human molecular genetics 20020501
Title: Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion.
Journal: The EMBO journal 20020501
Title: Role of apoptosis in the pathogenesis of acute renal failure.
Journal: Current opinion in nephrology and hypertension 20020501
Title: How should the immunosuppressive regimen be managed in patients with established chronic allograft failure?
Journal: Kidney international. Supplement 20020501
Title: Sirolimus allows renal recovery in lung and heart transplant recipients with chronic renal impairment.
Journal: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20020501
Title: Induction of apoptosis and modulation of activation and effector function in T cells by immunosuppressive drugs.
Journal: Clinical and experimental immunology 20020501
Title: ARTS I -- the rapamycin eluting stent; ARTS II -- the rosy prophecy.
Journal: European heart journal 20020501
Title: Muscarinic acetylcholine receptor activation induces Ca2+ mobilization and Na+/K+-ATPase activity inhibition in eel enterocytes.
Journal: The Journal of endocrinology 20020501
Title: Hemolytic uremic syndrome after renal transplantation: immunosuppressive therapy with rapamycin.
Journal: Nephron 20020501
Title: Protein modulators made to order.
Journal: Chemistry & biology 20020501
Title: Transcriptional response pathways in a yeast strain sensitive to saframycin a and a more potent analog: evidence for a common basis of activity.
Journal: Chemistry & biology 20020501
Title: Initial experience using rapamycin immunosuppression in pediatric intestinal transplant recipients.
Journal: Transplantation proceedings 20020501
Title: Improved results in small bowel transplantation using sirolimus.
Journal: Transplantation proceedings 20020501
Title: Tacrolimus, daclizumab, sirolimus, and budesonide after small bowel transplantation in order to reduce nephrotoxicity.
Journal: Transplantation proceedings 20020501
Title: Washing out of lipophilic compounds induces a transient increase in the passive Ca(2+) leak in permeabilized A7r5 cells.
Journal: Cell calcium 20020501
Title: Sirolimus does not exhibit nephrotoxicity compared to cyclosporine in renal transplant recipients.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20020501
Title: Twenty-eight-day efficacy and phamacokinetics of the sirolimus-eluting stent.
Journal: Coronary artery disease 20020501
Title: Drug coating improves stent performance.
Journal: Health news (Waltham, Mass.) 20020501
Title: Delayed low-level calcineurin inhibition promotes allospecific tolerance induction by posttransplantation donor leukocyte infusion.
Journal: Transplantation 20020427
Title: 4E-binding proteins, the suppressors of eukaryotic initiation factor 4E, are down-regulated in cells with acquired or intrinsic resistance to rapamycin.
Journal: The Journal of biological chemistry 20020419
Title: Quick guide: target of rapamycin.
Journal: Current biology : CB 20020416
Title: Msn2p/Msn4p act as a key transcriptional activator of yeast cytoplasmic thiol peroxidase II.
Journal: The Journal of biological chemistry 20020405
Title: Rapamycin eluting stent: the onset of a new era in interventional cardiology.
Journal: Heart (British Cardiac Society) 20020401
Title: Identification of a novel route of extraction of sirolimus in human small intestine: roles of metabolism and secretion.
Journal: The Journal of pharmacology and experimental therapeutics 20020401
Title: Translational control of cell fate: availability of phosphorylation sites on translational repressor 4E-BP1 governs its proapoptotic potency.
Journal: Molecular and cellular biology 20020401
Title: Fighting restenosis from the inside out.
Journal: Harvard heart letter : from Harvard Medical School 20020401
Title: Rapamune. New tablet combats kidney rejection.
Journal: Nursing 20020401
Title: Long-term care of pediatric renal transplant patients: from bench to bedside.
Journal: Current opinion in pediatrics 20020401
Title: Single-dose pharmacokinetics and tolerability of everolimus in stable pediatric renal transplant patients.
Journal: Pediatric transplantation 20020401
Title: Efficacy and toxicity of a protocol using sirolimus, tacrolimus and daclizumab in a nonhuman primate renal allotransplant model.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20020401
Title: The role of phosphatidylinositol 3-kinase, rho family GTPases, and STAT3 in Ros-induced cell transformation.
Journal: The Journal of biological chemistry 20020329
Title: Long-term kidney graft survival by delayed T cell ablative treatment in rhesus monkeys.
Journal: Transplantation 20020327
Title: Compared to mycophenolate mofetil, rapamycin induces significant changes on growth factors and growth factor receptors in the early days post-kidney transplantation.
Journal: Transplantation 20020327
Title: Exposure-response relationships for everolimus in de novo kidney transplantation: defining a therapeutic range.
Journal: Transplantation 20020327
Title: Insulin regulation of insulin-like growth factor-binding protein-1 gene expression is dependent on the mammalian target of rapamycin, but independent of ribosomal S6 kinase activity.
Journal: The Journal of biological chemistry 20020322
Title: Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner.
Journal: The Journal of biological chemistry 20020322
Title: Phosphorylation of 4E-BP1 is mediated by the p38/MSK1 pathway in response to UVB irradiation.
Journal: The Journal of biological chemistry 20020315
Title: De novo hemolytic uremic syndrome after kidney transplantation in patients treated with cyclosporine-sirolimus combination.
Journal: Transplantation 20020315
Title: Regulation of cap-dependent translation by insulin-like growth factor-1 in neuronal cells.
Journal: Biochemical and biophysical research communications 20020301
Title: The future role of target of rapamycin inhibitors in renal transplantation.
Journal: Current opinion in urology 20020301
Title: Stent-based antirestenotic coatings (sirolimus/paclitaxel).
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20020301
Title: Drug-eluting stents for the prevention of restenosis: in quest for the Holy Grail.
Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20020301
Title: Combination therapy with sirolimus and interleukin-2 prevents spontaneous and recurrent autoimmune diabetes in NOD mice.
Journal: Diabetes 20020301
Title: Strategies to reduce toxicities and improve outcomes in renal transplant recipients.
Journal: Pharmacotherapy 20020301
Title: Long-term viability of articular cartilage after microsurgical whole-joint transplantation and immunosuppression with rapamycin, mycophenolate mofetil, and tacrolimus.
Journal: The Journal of hand surgery 20020301
Title: The genome-wide localization of Rsc9, a component of the RSC chromatin-remodeling complex, changes in response to stress.
Journal: Molecular cell 20020301
Title: Simultaneous quantification of sirolimus, everolimus, tacrolimus and cyclosporine by liquid chromatography-mass spectrometry (LC-MS).
Journal: Clinical chemistry and laboratory medicine 20020301
Title: Mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitors restore anoikis sensitivity in human breast cancer cell lines with a constitutively activated extracellular-regulated kinase (ERK) pathway.
Journal: Molecular cancer therapeutics 20020301
Title: Bibliography. Current world literature. Renal medicine and renal transplantation.
Journal: Current opinion in urology 20020301
Title: FK506 induces chondrogenic differentiation of clonal mouse embryonic carcinoma cells, ATDC5.
Journal: European journal of pharmacology 20020222
Title: Effect of topical immunomodulators on acute allergic inflammation and bronchial hyperresponsiveness in sensitised rats.
Journal: European journal of pharmacology 20020222
Title: Overcoming restenosis with sirolimus: from alphabet soup to clinical reality.
Journal: Lancet (London, England) 20020216
Title: Cyclosporin A, FK506 and rapamycin produce multiple, temporally distinct, effects on memory following single-trial, passive avoidance training in the chick.
Journal: Brain research 20020215
Title: Early expression of myocardial HIF-1alpha in response to mechanical stresses: regulation by stretch-activated channels and the phosphatidylinositol 3-kinase signaling pathway.
Journal: Circulation research 20020208
Title: Identification of genes coding enzymes for ascomycin tetra-hydropyranose ring formation.
Journal: International journal of molecular medicine 20020201
Title: Update on pharmacokinetic/pharmacodynamic studies with FTY720 and sirolimus.
Journal: Therapeutic drug monitoring 20020201
Title: Early clinical experience with a novel rapamycin derivative.
Journal: Therapeutic drug monitoring 20020201
Title: International Federation of Clinical Chemistry/International Association of Therapeutic Drug Monitoring and Clinical Toxicology working group on immunosuppressive drug monitoring.
Journal: Therapeutic drug monitoring 20020201
Title: BCR signal through alpha 4 is involved in S6 kinase activation and required for B cell maturation including isotype switching and V region somatic hypermutation.
Journal: International immunology 20020201
Title: Calcineurin inhibitor-free CD28 blockade-based protocol protects allogeneic islets in nonhuman primates.
Journal: Diabetes 20020201
Title: Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor.
Journal: Nature medicine 20020201
Title: New tools for prevention of restenosis could decrease the 'oculo-stento' reflex.
Journal: Cardiovascular research 20020201
Title: Pharmacokinetic and pharmacodynamic assessments of HMG-CoA reductase inhibitors when coadministered with everolimus.
Journal: Journal of clinical pharmacology 20020201
Title: Effect of food on everolimus absorption: quantification in healthy subjects and a confirmatory screening in patients with renal transplants.
Journal: Pharmacotherapy 20020201
Title: Mammalian target of rapamycin (mTOR): pro- and anti-apoptotic.
Journal: Cell death and differentiation 20020201
Title: A novel conditional Akt 'survival switch' reversibly protects cells from apoptosis.
Journal: Gene therapy 20020201
Title: Protein phosphatase 2A on track for nutrient-induced signalling in yeast.
Journal: Molecular microbiology 20020201
Title: Combination therapy with low dose sirolimus and tacrolimus is synergistic in preventing spontaneous and recurrent autoimmune diabetes in non-obese diabetic mice.
Journal: Diabetologia 20020201
Title: [Radioactive stents: problems and potential solutions].
Journal: Herz 20020201
Title: Early cyclosporine a withdrawal in kidney transplant recipients under a sirolimus-based immunosuppressive regimen: pathological study of graft biopsies at 1-year posttransplant.
Journal: Transplantation proceedings 20020201
Title: Immunosuppression with sirolimus, cyclosporyne, and prednisone in renal transplantation.
Journal: Transplantation proceedings 20020201
Title: The limitations of calcineurin and mTOR inhibitors: new directions for immunosuppressive strategies.
Journal: Transplantation proceedings 20020201
Title: Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic.
Journal: Current opinion in investigational drugs (London, England : 2000) 20020201
Title: Swinging the vote for rapamycin.
Journal: Nature reviews. Cancer 20020201
Title: Coating stents with antirestenotic drugs: the blunderbuss or the magic bullet?
Journal: Circulation 20020129
Title: Rapamycin increases transforming growth factor-beta mRNA expression in immortalized rat proximal renal tubular cells.
Journal: Transplantation 20020127
Title: Increased activity of c-Src and Csk in fibroblasts transformed by v-src oncogene.
Journal: Biochemical and biophysical research communications 20020118
Title: Igs from patients with Graves' disease induce the expression of T cell chemoattractants in their fibroblasts.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020115
Title: Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin.
Journal: Blood 20020115
Title: Cell cycle kinesis in lymphocytes in the diagnosis of Alzheimer's disease.
Journal: Neuroscience letters 20020111
Title: Autocrine heregulin generates growth factor independence and blocks apoptosis in colon cancer cells.
Journal: Oncogene 20020103
Title: Inhibition of PI3K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP-2.
Journal: FEBS letters 20020102
Title: FK506 enhanced osteoblastic differentiation in mesenchymal cells.
Journal: Cell biology international 20020101
Title: Synergism of RAD and cyclosporin A in prevention of acute rat corneal allograft rejection.
Journal: Cornea 20020101
Title: MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders.
Journal: BMC cell biology 20020101
Title: Differential influence of two cyclosporine formulations on everolimus pharmacokinetics: a clinically relevant pharmacokinetic interaction.
Journal: Journal of clinical pharmacology 20020101
Title: Post-liver transplantation immunosuppression: the song does not remain the same.
Journal: Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20020101
Title: Preparing for the introduction of new technologies: who is going to pay for them?
Journal: The Journal of cardiovascular management : the official journal of the American College of Cardiovascular Administrators 20020101
Title: Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritis.
Journal: Arthritis research 20020101
Title: Vector algebra in the analysis of genome-wide expression data.
Journal: Genome biology 20020101
Title: Current immunosuppression in liver transplantation.
Journal: American journal of therapeutics 20020101
Title: Quantification of sirolimus by liquid chromatography-tandem mass spectrometry using on-line solid-phase extraction.
Journal: Clinical chemistry and laboratory medicine 20020101
Title: Novel pharmacotherapeutic approaches to prevention and treatment of GVHD.
Journal: Drugs 20020101
Title: Newer immunosuppressive drugs: their potential role in rheumatoid arthritis therapy.
Journal: Drugs 20020101
Title: Role of mTOR in the degradation of IRS-1: regulation of PP2A activity.
Journal: Journal of cellular biochemistry 20020101
Title: Drug-eluting stents in the treatment of atherosclerotic coronary heart disease.
Journal: Indian heart journal 20020101
Title: [The novel immunodepressant rapamune].
Journal: Eksperimental'naia i klinicheskaia farmakologiia 20020101
Title: Single-agent immunosuppression after liver transplantation: what is possible?
Journal: Drugs 20020101
Title: Optimization and direct comparison of the dimerizer and reverse tet transcriptional control systems.
Journal: The journal of gene medicine 20020101
Title: Sirolimus: has it gained from experience with older drugs?
Journal: Therapie 20020101
Title: Sirolimus-eluting stents: the novel application of basic science to coronary artery disease.
Journal: Irish medical journal 20020101
Title: [Problem with restenosis in connection to balloon angioplasty near to be solved].
Journal: Duodecim; laaketieteellinen aikakauskirja 20020101
Title: Side-chain modified vitamin D analogs require activation of both PI 3-K and erk1,2 signal transduction pathways to induce differentiation of human promyelocytic leukemia cells.
Journal: Acta biochimica Polonica 20020101
Title: Calcineurin inhibitor-induced chronic nephrotoxicity in liver transplant patients is reversible using rapamycin as the primary immunosuppressive agent.
Journal: Clinical transplantation 20020101
Title: Four birds with one stone: RAPA as potential anticancer therapy.
Journal: Cancer biology & therapy 20020101
Title: The macrolide immunosuppressants in dermatology: mechanisms of action.
Journal: European journal of dermatology : EJD 20020101
Title: Rapamycin insensitivity in Schistosoma mansoni is not due to FKBP12 functionality.
Journal: Molecular and biochemical parasitology 20020101
Title: Clinical experience with drug-eluting stents.
Journal: Reviews in cardiovascular medicine 20020101
Title: What will be the impact of drug-eluting stents on hybrid coronary revascularization?
Journal: The heart surgery forum 20020101
Title: Drug eluting stents: initial experiences.
Journal: Zeitschrift fur Kardiologie 20020101
Title: Sirolimus-eluting stents: a review of experimental and clinical findings.
Journal: Zeitschrift fur Kardiologie 20020101
Title: Perspectives of drug-eluting stents: the next revolution.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101
Title: Super stents keep the blood flowing. New technology leaves damaged arteries wide open and unclogged.
Journal: Heart advisor 20020101
Title: Sirolimus (rapamycin) for the treatment of steroid-refractory acute graft-versus-host disease.
Journal: Transplantation 20011227
Title: Improving tolerability of immunosuppressive regimens.
Journal: Transplantation 20011227
Title: Prospective monitoring of BK virus load after discontinuing sirolimus treatment in a renal transplant patient with BK virus nephropathy.
Journal: The Journal of infectious diseases 20011201
Title: Regulation of Id2 gene expression by the type 1 IGF receptor and the insulin receptor substrate-1.
Journal: Endocrinology 20011201
Title: Tailoring immunosuppressive therapy for renal transplant recipients.
Journal: Pediatric transplantation 20011201
Title: The immunomodulatory drugs cyclosporin A, mycophenolate mofetil, and sirolimus (rapamycin) inhibit allergen-induced proliferation and IL-5 production by PBMCs from atopic asthmatic patients.
Journal: The Journal of allergy and clinical immunology 20011201
Title: 14-3-3 Proteins are essential for regulation of RTG3-dependent transcription in Saccharomyces cerevisiae.
Journal: Yeast (Chichester, England) 20011201
Title: Cyclic stretch enhances the expression and activity of coronary endothelium-derived hyperpolarizing factor synthase.
Journal: Hypertension (Dallas, Tex. : 1979) 20011201
Title: Single-point calibration for sirolimus quantification.
Journal: Therapeutic drug monitoring 20011201
Title: Nephrotoxicity of immunosuppressive drugs: new insight and preventive strategies.
Journal: Current opinion in critical care 20011201
Title: Insulin release and suppression by tacrolimus, rapamycin and cyclosporin A are through regulation of the ATP-sensitive potassium channel.
Journal: Diabetes, obesity & metabolism 20011201
Title: Mechanisms of resistance to rapamycins.
Journal: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20011201
Title: [Mechanism in the cytoplasm accumulation of TOP binding factor].
Journal: The Japanese journal of antibiotics 20011201
Title: Nerve growth factor uses Ras/ERK and phosphatidylinositol 3-kinase cascades to up-regulate the N-methyl-D-aspartate receptor 1 promoter.
Journal: The Journal of biological chemistry 20011130
Title: Ribosomal protein S6 phosphorylation and function during late gestation liver development in the rat.
Journal: The Journal of biological chemistry 20011130
Title: Phosphatidic acid-mediated mitogenic activation of mTOR signaling.
Journal: Science (New York, N.Y.) 20011130
Title: American Heart Association 2001 scientific sessions: late-breaking science-drug-eluting stents.
Journal: Circulation 20011120
Title: Brain-derived neurotrophic factor enhances neuronal translation by activating multiple initiation processes: comparison with the effects of insulin.
Journal: The Journal of biological chemistry 20011116
Title: Antagonistic roles for CTLA-4 and the mammalian target of rapamycin in the regulation of clonal anergy: enhanced cell cycle progression promotes recall antigen responsiveness.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20011115
Title: Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells.
Journal: The EMBO journal 20011115
Title: Phosphorylation and local presynaptic protein synthesis in calcium- and calcineurin-dependent induction of crayfish long-term facilitation.
Journal: Neuron 20011108
Title: ErbB2-overexpressing human mammary carcinoma cells display an increased requirement for the phosphatidylinositol 3-kinase signaling pathway in anchorage-independent growth.
Journal: Oncogene 20011108
Title: Mammalian TOR: a homeostatic ATP sensor.
Journal: Science (New York, N.Y.) 20011102
Title: Rapamycin increases the cellular concentration of the BCL-2 protein and exerts an anti-apoptotic effect.
Journal: European journal of cancer (Oxford, England : 1990) 20011101
Title: Rapamycin and less immunosuppressive analogs are toxic to Candida albicans and Cryptococcus neoformans via FKBP12-dependent inhibition of TOR.
Journal: Antimicrobial agents and chemotherapy 20011101
Title: Macrolactam immunomodulators for topical treatment of inflammatory skin diseases.
Journal: Journal of the American Academy of Dermatology 20011101
Title: The sirolimus coated stent: will the Achilles heel of interventional cardiology finally be cured?
Journal: European heart journal 20011101
Title: Coronary restenosis elimination with a sirolimus eluting stent: first European human experience with 6-month angiographic and intravascular ultrasonic follow-up.
Journal: European heart journal 20011101
Title: Hierarchical phosphorylation of the translation inhibitor 4E-BP1.
Journal: Genes & development 20011101
Title: Targeting keratinocyte apoptosis in the treatment of atopic dermatitis and allergic contact dermatitis.
Journal: The Journal of allergy and clinical immunology 20011101
Title: Noradrenaline-induced increase in protein synthesis in adult rat cardiomyocytes: involvement of only alpha1A-adrenoceptors.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20011101
Title: Influence of hepatic impairment on everolimus pharmacokinetics: implications for dose adjustment.
Journal: Clinical pharmacology and therapeutics 20011101
Title: Distinct regulatory mechanism for p70 S6 kinase beta from that for p70 S6 kinase alpha.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20011101
Title: TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway.
Journal: Molecular cell 20011101
Title: Estrogen and rapamycin effects on cell cycle progression in T47D breast cancer cells.
Journal: Breast cancer research and treatment 20011101
Title: Sirolimus: a comprehensive review.
Journal: Expert opinion on pharmacotherapy 20011101
Title: Mutagenesis of the rapamycin producer Streptomyces hygroscopicus FC904.
Journal: The Journal of antibiotics 20011101
Title: Binding of the La autoantigen to the 5' untranslated region of a chimeric human translation elongation factor 1A reporter mRNA inhibits translation in vitro.
Journal: Biochimica et biophysica acta 20011031
Title: Provocative effects of the immunosuppressants rapamycin, tacrolimus, and dexamethasone on pneumonitis in contrast to the anti- pneumonitis effects of mycophenolate mofetil.
Journal: Transplantation 20011027
Title: Living the dream of no restenosis.
Journal: Circulation 20011023
Title: Sustained suppression of neointimal proliferation by sirolimus-eluting stents: one-year angiographic and intravascular ultrasound follow-up.
Journal: Circulation 20011023
Title: Rapamycin's resurrection: a new way to target the cancer cell cycle.
Journal: Journal of the National Cancer Institute 20011017
Title: Rapamycin may prevent post-transplant lymphoma.
Journal: Journal of the National Cancer Institute 20011017
Title: Pharmacological characterization of the putative cADP-ribose receptor.
Journal: The Biochemical journal 20011015
Title: A WASp-VASP complex regulates actin polymerization at the plasma membrane.
Journal: The EMBO journal 20011015
Title: Rapamycin: clinical results and future opportunities.
Journal: Transplantation 20011015
Title: Effect of sirolimus on the metabolism of apoB100- containing lipoproteins in renal transplant patients.
Journal: Transplantation 20011015
Title: Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling.
Journal: Oncogene 20011011
Title: Rapamycin impairs recovery from acute renal failure: role of cell-cycle arrest and apoptosis of tubular cells.
Journal: American journal of physiology. Renal physiology 20011001
Title: Internal ribosome entry segment-mediated initiation of c-Myc protein synthesis following genotoxic stress.
Journal: The Biochemical journal 20011001
Title: Rapamycin-sensitive phase of 3T3-L1 preadipocyte differentiation after clonal expansion.
Journal: Journal of cellular physiology 20011001
Title: Target of rapamycin (TOR) inhibition in renal transplantation: Clinical uses in various populations. Introduction.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001
Title: Cyclosporine elimination in the presence of TOR inhibitors: effects on renal function, acute rejection, and safety.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001
Title: Safety and efficacy of TOR inhibitors and other immunosuppressive regimens in African-American renal transplant recipients.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001
Title: Sirolimus and mycophenolate mofetil for calcineurin-free immunosuppression in renal transplant recipients.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001
Title: Safety and efficacy of TOR inhibitors in pediatric renal transplant recipients.
Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001
Title: From beach to bedside: history of the development of sirolimus.
Journal: Therapeutic drug monitoring 20011001
Title: Use of rapamycin in a transplant patient who developed cyclosporin neurotoxicity.
Journal: Pediatric nephrology (Berlin, Germany) 20011001
Title: Efficacy of SDZ RAD compared with CsA monotherapyand combined Rad/FTY720 treatment in a murine cardiac allotransplantation model.
Journal: Transplant immunology 20011001
Title: Comparative study analyzing effects of sirolimus-cyclosporin and sirolimus-tacrolimus combinations on bile flow in the rat.
Journal: Digestive diseases and sciences 20011001
Title: The mammalian target of rapamycin regulates C2C12 myogenesis via a kinase-independent mechanism.
Journal: The Journal of biological chemistry 20010928
Title: Lysophosphatidic acid activates the 70-kDa S6 kinase via the lipoxygenase pathway.
Journal: Biochemical and biophysical research communications 20010928
Title: Fluvastatin in combination with rad significantly reduces graft vascular disease in rat cardiac allografts.
Journal: Transplantation 20010927
Title: Immune cells and immunosuppression in a porcine bronchial model of obliterative bronchiolitis.
Journal: Transplantation 20010927
Title: Interstitial pneumonitis associated with sirolimus (rapamycin) therapy after liver transplantation.
Journal: Transplantation 20010927
Title: Damaged microtubules can inactivate BCL-2 by means of the mTOR kinase.
Journal: Oncogene 20010927
Title: Drug points: Premature osteonecrosis and sirolimus treatment in renal transplantation.
Journal: BMJ (Clinical research ed.) 20010922
Title: Immunosuppressant rapamycin inhibits protein kinase C alpha and p38 mitogen-activated protein kinase leading to the inhibition of chondrogenesis.
Journal: European journal of pharmacology 20010921
Title: An important role of CDK inhibitor p18(INK4c) in modulating antigen receptor-mediated T cell proliferation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010915
Title: Sirolimus: another cause of drug-induced interstitial pneumonitis.
Journal: Transplantation 20010915
Title: Sirolimus: searching for its niche or a therapy that has come of age?
Journal: Transplantation 20010915
Title: Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure.
Journal: Transplantation 20010915
Title: Characteristics of sirolimus-associated interstitial pneumonitis in renal transplant patients.
Journal: Transplantation 20010915
Title: Sirolimus for rescue and primary immunosuppression in transplanted children receiving tacrolimus.
Journal: Transplantation 20010915
Title: Interleukin-15 is the main mediator of lymphocyte proliferation in cultures mixed with human kidney tubular epithelial cells.
Journal: Transplantation 20010915
Title: Selective inhibition of IL-2 gene expression by IL-2 antisense oligonucleotides blocks heart allograft rejection.
Journal: Transplantation 20010915
Title: Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration.
Journal: Circulation research 20010914
Title: Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model.
Journal: Circulation 20010904
Title: Bystander activation involving T lymphocytes in herpetic stromal keratitis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010901
Title: Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27(kip1).
Journal: Blood 20010901
Title: Efficacy of sirolimus (rapamycin) administered concomitantly with a subtherapeutic dose of cyclosporin in the treatment of severe psoriasis: a randomized controlled trial.
Journal: The British journal of dermatology 20010901
Title: Sirolimus inhibition of lymphocyte proliferation is not antagonized by ciprofloxacin and other quinolone antibiotics.
Journal: Transplantation proceedings 20010901
Title: Population pharmacokinetics of everolimus in de novo renal transplant patients: impact of ethnicity and comedications.
Journal: Clinical pharmacology and therapeutics 20010901
Title: mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer.
Journal: Endocrine-related cancer 20010901
Title: Regeneration in avian hair cell epithelia: identification of intracellular signals required for S-phase entry.
Journal: The European journal of neuroscience 20010901
Title: [Complications in kidney transplantation].
Journal: Presse medicale (Paris, France : 1983) 20010901
Title: [Focus on Islets of Langerhans transplantation].
Journal: Presse medicale (Paris, France : 1983) 20010901
Title: [mTOR and FTY 720 inhibitors].
Journal: Presse medicale (Paris, France : 1983) 20010901
Title: [Immunosuppression, ongoing clinical trials].
Journal: Presse medicale (Paris, France : 1983) 20010901
Title: Cholestasis and regulation of genes related to drug metabolism and biliary transport in rat liver following treatment with cyclosporine A and sirolimus (Rapamycin).
Journal: Pharmacology & toxicology 20010901
Title: Everolimus. Novartis.
Journal: Current opinion in investigational drugs (London, England : 2000) 20010901
Title: Cross-talk between the ERK and p70 S6 kinase (S6K) signaling pathways. MEK-dependent activation of S6K2 in cardiomyocytes.
Journal: The Journal of biological chemistry 20010831
Title: Bench to bedside: the development of rapamycin and its application to stent restenosis.
Journal: Circulation 20010821
Title: A maize insulin-like growth factor signals to a transduction pathway that regulates protein synthesis in maize.
Journal: The Biochemical journal 20010815
Title: FK506 promotes adenosine release from endothelial cells via inhibition of adenosine kinase.
Journal: European journal of pharmacology 20010810
Title: Ammonia regulates VID30 expression and Vid30p function shifts nitrogen metabolism toward glutamate formation especially when Saccharomyces cerevisiae is grown in low concentrations of ammonia.
Journal: The Journal of biological chemistry 20010803
Title: Coexpression of CD4 and CD8alpha on rat T-cells in whole blood: a sensitive marker for monitoring T-cell immunosuppressive drugs.
Journal: Journal of immunological methods 20010801
Title: HGF- and KGF-induced activation of PI-3K/p70 s6 kinase pathway in corneal epithelial cells: its relevance in wound healing.
Journal: Experimental eye research 20010801
Title: Regulation of glycogen synthesis in human muscle cells.
Journal: Biochemical Society transactions 20010801
Title: Orthotopic liver transplantation using low-dose tacrolimus and sirolimus.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20010801
Title: In vitro immunosuppressive activity of tacrolimus dihydrodiol precursors obtained by chemical oxidation and identification of a new metabolite of SDZ-RAD by electrospray and electrospray-linked scan mass spectrometry.
Journal: Journal of mass spectrometry : JMS 20010801
Title: Staurosporine inhibits phosphorylation of translational regulators linked to mTOR.
Journal: Cell death and differentiation 20010801
Title: Natural products as immunosuppressive agents.
Journal: Natural product reports 20010801
Title: Advances in systemic therapy of small cell cancer of the lung.
Journal: Expert review of anticancer therapy 20010801
Title: Cdc25A phosphatase suppresses apoptosis induced by serum deprivation.
Journal: Oncogene 20010727
Title: Sirolimus-associated eyelid edema in kidney transplant recipients.
Journal: Transplantation 20010715
Title: Phosphorylation regulates the interaction between Gln3p and the nuclear import factor Srp1p.
Journal: The Journal of biological chemistry 20010706
Title: Rapamycin blocks sexual development in fission yeast through inhibition of the cellular function of an FKBP12 homolog.
Journal: The Journal of biological chemistry 20010706
Title: Flow cytometric quantitation of calcium-dependent and -independent mitogen-stimulation of T cell functions in whole blood: inhibition by immunosuppressive drugs in vitro.
Journal: Journal of immunological methods 20010701
Title: Angiotensin II regulates phosphorylation of translation elongation factor-2 in cardiac myocytes.
Journal: American journal of physiology. Heart and circulatory physiology 20010701
Title: Rapamycin induces apoptosis in monocyte- and CD34-derived dendritic cells but not in monocytes and macrophages.
Journal: Blood 20010701
Title: Combined effect of cyclosporine and sirolimus on improving the longevity of recombinant adenovirus-mediated transgene expression in the retina.
Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20010701
Title: Cell cycle protein expression in vascular smooth muscle cells in vitro and in vivo is regulated through phosphatidylinositol 3-kinase and mammalian target of rapamycin.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20010701
Title: Median effect analysis of efficacy versus adverse effects of immunosuppressants.
Journal: Clinical pharmacology and therapeutics 20010701
Title: Sirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brain.
Journal: British journal of pharmacology 20010701
Title: The effect of different immunosuppressants on alloantigen dependent and independent factors involved in the development of chronic rejection in an animal model.
Journal: Annals of the Royal College of Surgeons of England 20010701
Title: New developments in the prophylaxis and treatment of graft versus host disease.
Journal: Expert opinion on pharmacotherapy 20010701
Title: Cell cycle and cell migration: new pieces to the puzzle.
Journal: Circulation 20010619
Title: Role for p27(Kip1) in Vascular Smooth Muscle Cell Migration.
Journal: Circulation 20010619
Title: Activation loop sequences confer substrate specificity to phosphoinositide 3-kinase alpha (PI3Kalpha ). Functions of lipid kinase-deficient PI3Kalpha in signaling.
Journal: The Journal of biological chemistry 20010615
Title: Signal transduction pathways involved in phosphorylation and activation of p70S6K following exposure to UVA irradiation.
Journal: The Journal of biological chemistry 20010615
Title: Sirolimus rescue therapy for refractory rejection in renal transplantation.
Journal: Transplantation 20010615
Title: Effect of low dose cyclosporine and sirolimus on hepatic drug metabolism in the rat1.
Journal: Transplantation 20010615
Title: Vascular and cellular mechanisms of chronic renal allograft dysfunction.
Journal: Transplantation 20010615
Title: Exploring treatment options in renal transplantation: the problems of chronic allograft dysfunction and drug-related nephrotoxicity.
Journal: Transplantation 20010615
Title: Potential therapeutic interventions to avoid or treat chronic allograft dysfunction.
Journal: Transplantation 20010615
Title: Regulation of the levels of small heat-shock proteins during differentiation of C2C12 cells.
Journal: Experimental cell research 20010610
Title: Coupled gating between cardiac calcium release channels (ryanodine receptors).
Journal: Circulation research 20010608
Title: Metabolism of sirolimus and its derivative everolimus by cytochrome P450 3A4: insights from docking, molecular dynamics, and quantum chemical calculations.
Journal: Journal of medicinal chemistry 20010607
Title: A high-capacity quantitative mouse model of drug-mediated immunosuppression based on rejection of an allogeneic subcutaneous tumor.
Journal: The Journal of pharmacology and experimental therapeutics 20010601
Title: Cell proliferation through forced engagement of c-Kit and Flt-3.
Journal: Blood 20010601
Title: Insulin-like growth factor-I augments prolactin and inhibits growth hormone release through distinct as well as overlapping cellular signaling pathways.
Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010601
Title: Effect of p27 deficiency and rapamycin on intimal hyperplasia: in vivo and in vitro studies using a p27 knockout mouse model.
Journal: Laboratory investigation; a journal of technical methods and pathology 20010601
Title: Biochemical correlates of mTOR inhibition by the rapamycin ester CCI-779 and tumor growth inhibition.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20010601
Title: Simultaneous simple and fast quantification of three major immunosuppressants by liquid chromatography--tandem mass-spectrometry.
Journal: Clinical biochemistry 20010601
Title: mTOR inhibitors: an overview.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20010601
Title: Sirolimus improves the two-year outcome of renal allografts in African-American patients.
Journal: Transplant international : official journal of the European Society for Organ Transplantation 20010601
Title: RAD in de novo renal transplantation: comparison of three doses on the incidence and severity of acute rejection.
Journal: Transplantation 20010527
Title: FRAP-p70s6K signaling is required for pancreatic cancer cell proliferation.
Journal: The Journal of surgical research 20010515
Title: A calcineurin antagonist-free induction strategy for immunosuppression in cadaveric kidney transplant recipients at risk for delayed graft function.
Journal: Transplantation 20010515
Title: New drug development in non-Hodgkin lymphomas.
Journal: Current oncology reports 20010501
Title: Up-regulation of cell surface sodium channels by cyclosporin A, FK506, and rapamycin in adrenal chromaffin cells.
Journal: The Journal of pharmacology and experimental therapeutics 20010501
Title: Sanglifehrin A, a novel cyclophilin-binding immunosuppressant, inhibits IL-2-dependent T cell proliferation at the G1 phase of the cell cycle.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010501
Title: Pharmacokinetic interactions augment toxicities of sirolimus/cyclosporine combinations.
Journal: Journal of the American Society of Nephrology : JASN 20010501
Title: Flow-induced DNA synthesis requires signaling to a translational control pathway.
Journal: The Journal of surgical research 20010501
Title: Endotoxin (LPS) stimulates 4E-BP1/PHAS-I phosphorylation in macrophages.
Journal: The Journal of surgical research 20010501
Title: Dyslipidemia during sirolimus therapy in liver transplant recipients occurs with concomitant cyclosporine but not tacrolimus.
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20010501
Title: Induction of differentiation of human myeloid leukemia cells by immunosuppressant macrolides (rapamycin and FK506) and calcium/calmodulin-dependent kinase inhibitors.
Journal: Experimental hematology 20010501
Title: Overview of side effects of immunosuppressive therapy.
Journal: Transplantation proceedings 20010501
Title: Assessment of mechanisms of action of immunosuppressive drugs using novel whole blood assays.
Journal: Transplantation proceedings 20010501
Title: Sirolimus and erythromycin interaction: two cases.
Journal: Transplantation proceedings 20010501
Title: Overview of clinical trials with new agents.
Journal: Transplantation proceedings 20010501
Title: Phase III trial of Rapamune versus placebo in primary renal allograft recipients.
Journal: Transplantation proceedings 20010501
Title: RAD reduces compensatory renal graft hypertrophy in a rat model of chronic rejection.
Journal: Transplantation proceedings 20010501
Title: FTY-720 is efficacious in monkey kidney transplantation.
Journal: Transplantation proceedings 20010501
Title: Adjunctive rapamycin and CsA treatment inhibits monocyte/macrophage associated cytokines/chemokines in sensitized cardiac graft recipients.
Journal: Transplantation 20010427
Title: p53/p21(CIP1) cooperate in enforcing rapamycin-induced G(1) arrest and determine the cellular response to rapamycin.
Journal: Cancer research 20010415
Title: Akt mediates insulin induction of glucose uptake and up-regulation of GLUT4 gene expression in brown adipocytes.
Journal: FEBS letters 20010413
Title: Rapamycin-insensitive regulation of 4e-BP1 in regenerating rat liver.
Journal: The Journal of biological chemistry 20010406
Title: Regulation of translation initiation by FRAP/mTOR.
Journal: Genes & development 20010401
Title: Liver transplantation using sirolimus and minimal corticosteroids (3-day taper).
Journal: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20010401
Title: Prevention of neointimal proliferation by immunosuppression in synthetic vascular grafts.
Journal: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20010401
Title: Review: uveitis and immunosuppressive drugs.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010401
Title: Signalling pathways regulating the dephosphorylation of Ser729 in the hydrophobic domain of protein kinase Cepsilon upon cell passage.
Journal: The Journal of biological chemistry 20010330
Title: The TOR kinases link nutrient sensing to cell growth.
Journal: The Journal of biological chemistry 20010330
Title: The cell survival signal Akt is differentially activated by PDGF-BB, EGF, and FGF-2 in osteoblastic cells.
Journal: Journal of cellular biochemistry 20010326
Title: [Prevention of instant restenosis after coronary angioplasty by implantation of rapamycin-coated stents].
Journal: Ugeskrift for laeger 20010319
Title: The fission yeast TOR homolog, tor1+, is required for the response to starvation and other stresses via a conserved serine.
Journal: The Journal of biological chemistry 20010309
Title: Regulation of APG14 expression by the GATA-type transcription factor Gln3p.
Journal: The Journal of biological chemistry 20010302
Title: Involvement of both phosphatidylinositol 3-kinase and p44/p42 mitogen-activated protein kinase pathways in the short-term regulation of pyruvate kinase L by insulin.
Journal: Endocrinology 20010301
Title: Uncoupling p70(s6) kinase activation and proliferation: rapamycin-resistant proliferation of human CD8(+) T lymphocytes.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010301
Title: New immunosuppressive drugs: an update.
Journal: Current opinion in urology 20010301
Title: Failure of GPI compounds to display neurotrophic activity in vitro and in vivo.
Journal: European journal of pharmacology 20010301
Title: Use of sirolimus in kidney transplantation.
Journal: Progress in transplantation (Aliso Viejo, Calif.) 20010301
Title: Deletion of rapQONML from the rapamycin gene cluster of Streptomyces hygroscopicus gives production of the 16-O-desmethyl-27-desmethoxy analog.
Journal: The Journal of antibiotics 20010301
Title: Treatment of transplant rejection: are the traditional immunosuppressants good enough?
Journal: Current opinion in investigational drugs (London, England : 2000) 20010301
Title: Translation initiation of the insulin-like growth factor I receptor mRNA is mediated by an internal ribosome entry site.
Journal: The Journal of biological chemistry 20010223
Title: Antitumor activity of the rapamycin analog CCI-779 in human primitive neuroectodermal tumor/medulloblastoma models as single agent and in combination chemotherapy.
Journal: Cancer research 20010215
Title: Overexpression of FK506-binding protein FKBP12.6 in cardiomyocytes reduces ryanodine receptor-mediated Ca(2+) leak from the sarcoplasmic reticulum and increases contractility.
Journal: Circulation research 20010202
Title: Impaired phosphate handling of renal allografts is aggravated under rapamycin-based immunosuppression.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010201
Title: The rapamycin sensitivity of human T-cell leukaemia virus type I-induced T-cell proliferation is mediated independently of the polypyrimidine motifs in the 5' long terminal repeat.
Journal: The Journal of general virology 20010201
Title: Solubilization of rapamycin.
Journal: International journal of pharmaceutics 20010201
Title: Sirolimus interferes with the innate response to bacterial products in human whole blood by attenuation of IL-10 production.
Journal: Scandinavian journal of immunology 20010201
Title: The flightless I protein colocalizes with actin- and microtubule-based structures in motile Swiss 3T3 fibroblasts: evidence for the involvement of PI 3-kinase and Ras-related small GTPases.
Journal: Journal of cell science 20010201
Title: Stent coatings.
Journal: The Journal of invasive cardiology 20010201
Title: 40-O-(2-hydroxyethyl)-rapamycin attenuates pulmonary arterial hypertension and neointimal formation in rats.
Journal: American journal of respiratory and critical care medicine 20010201
Title: [Effect of rapamycin on cytoplasmic accumulation of hetero nuclear ribonucleoprotein C-like unwinding protein 2].
Journal: The Japanese journal of antibiotics 20010201
Title: A worldwide, phase III, randomized, controlled, safety and efficacy study of a sirolimus/cyclosporine regimen for prevention of acute rejection in recipients of primary mismatched renal allografts.
Journal: Transplantation 20010127
Title: Frap-dependent serine phosphorylation of IRS-1 inhibits IRS-1 tyrosine phosphorylation.
Journal: Biochemical and biophysical research communications 20010126
Title: [Rapamycin: a new immunosuppressive agent capable of inhibiting chronic rejection?].
Journal: Casopis lekaru ceskych 20010119
Title: Lack of neointimal proliferation after implantation of sirolimus-coated stents in human coronary arteries: a quantitative coronary angiography and three-dimensional intravascular ultrasound study.
Journal: Circulation 20010116
Title: Insulin inhibits glucocorticoid-stimulated L-type 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene expression by activation of the c-Jun N-terminal kinase pathway.
Journal: The Biochemical journal 20010115
Title: Serotonin activates S6 kinase in a rapamycin-sensitive manner in Aplysia synaptosomes.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010115
Title: Intracellular signals that control cell proliferation in mammalian balance epithelia: key roles for phosphatidylinositol-3 kinase, mammalian target of rapamycin, and S6 kinases in preference to calcium, protein kinase C, and mitogen-activated protein kinase.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010115
Title: Pharmacokinetics and tolerability of 40-0-[2-hydroxyethyl]rapamycin in de novo liver transplant recipients.
Journal: Transplantation 20010115
Title: Regulation of glycogen synthesis by amino acids in cultured human muscle cells.
Journal: The Journal of biological chemistry 20010112
Title: Effects of immunosuppressants on receptor activator of NF-kappaB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells.
Journal: Biochemical and biophysical research communications 20010112
Title: Relative resistance in the development of T cell anergy in CD4+ T cells from simian immunodeficiency virus disease-resistant sooty mangabeys.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010101
Title: Counter-regulation of cytolytic activity and cytokine production in HIV-1-specific murine CD8+ cytotoxic T lymphocytes by free antigenic peptide.
Journal: International immunology 20010101
Title: Rapamycin in transplantation: a review of the evidence.
Journal: Kidney international 20010101
Title: Phosphatidylinositol-3,4,5-trisphosphate is required for insulin-like growth factor 1-mediated survival of 3T3-L1 preadipocytes.
Journal: Endocrinology 20010101
Title: Induction of the C/EBP homologous protein (CHOP) by amino acid deprivation requires insulin-like growth factor I, phosphatidylinositol 3-kinase, and mammalian target of rapamycin signaling.
Journal: Endocrinology 20010101
Title: Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation.
Journal: Diabetes 20010101
Title: Immunosuppressant use without bone loss--implications for bone loss after transplantation.
Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010101
Title: Pharmacokinetic interaction between single oral doses of diltiazem and sirolimus in healthy volunteers.
Journal: Clinical pharmacology and therapeutics 20010101
Title: Longitudinal assessment of everolimus in de novo renal transplant recipients over the first post-transplant year: pharmacokinetics, exposure-response relationships, and influence on cyclosporine.
Journal: Clinical pharmacology and therapeutics 20010101
Title: Sirolimus: a new promising immunosuppressive drug. Towards a rationale for its use in renal transplantation.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101
Title: Evidence that phosphorylation of human Upfl protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive PI 3-kinase-related kinase signaling pathway.
Journal: RNA (New York, N.Y.) 20010101
Title: Immunosuppressive drugs in paediatric liver transplantation.
Journal: Paediatric drugs 20010101
Title: Rapamycin for GVHD prophylaxis--potential for severe myelotoxicity.
Journal: Bone marrow transplantation 20010101
Title: Involvement of p70 S6 kinase in bone morphogenetic protein signaling: vascular endothelial growth factor synthesis by bone morphogenetic protein-4 in osteoblasts.
Journal: Journal of cellular biochemistry 20010101
Title: Strategies for induction of clinical tolerance.
Journal: Transplantation proceedings 20010101
Title: Expression of MHC class II antigen is essential in tolerance induction by donor bone marrow cell in antilymphocyte serum-treated and rapamycin-treated mice.
Journal: Transplantation proceedings 20010101
Title: Induction of peripheral tolerance by posttransplant infusion of donor splenocytes.
Journal: Transplantation proceedings 20010101
Title: Addition of rapamycin to cyclosporine-prednisone based immunosuppression reduces the clinical risk of pretransplant anti-HLA antibody.
Journal: Transplantation proceedings 20010101
Title: Temporary treatment with sirolimus and low-trough cyclosporine prevents acute islet allograft rejection, and combination with starch-conjugated deferoxamine promotes islet engraftment in the preclinical pig model.
Journal: Transplantation proceedings 20010101
Title: Comparison of the in vitro metabolism of the macrolide immunosuppressants sirolimus and RAD.
Journal: Transplantation proceedings 20010101
Title: Rapamycin reduces expression of fibrosis-associated genes in an experimental model of renal ischaemia reperfusion injury.
Journal: Transplantation proceedings 20010101
Title: Donor pretreatment of grafts from marginal donors improves long-term graft outcome.
Journal: Transplantation proceedings 20010101
Title: Sirolimus is effective for prevention of acute rejection in primary mismatched renal allograft recipients.
Journal: Transplantation proceedings 20010101
Title: Sirolimus rescue therapy for refractory rejection in renal transplant recipients.
Journal: Transplantation proceedings 20010101
Title: Effect of rapamycin and FK506 on mesangial cell proliferation.
Journal: Transplantation proceedings 20010101
Title: Sirolimus-tacrolimus combination for combined kidney-pancreas transplantation: effect on renal function.
Journal: Transplantation proceedings 20010101
Title: Sirolimus does not potentiate indices of chronic cyclosporin nephrotoxicity.
Journal: Transplantation proceedings 20010101
Title: A single-center open label randomized trial of the safety and efficacy of the use of sirolimus versus azathioprine in one-haplotype living related kidney transplant recipients-preliminary results.
Journal: Transplantation proceedings 20010101
Title: Cyclosporine and tacrolimus alter renin-angiotesin system in mouse medullary-thick ascending limb cultured cells.
Journal: Transplantation proceedings 20010101
Title: Rescue therapy: a role for sirolimus in lung and heart transplant recipients.
Journal: Transplantation proceedings 20010101
Title: Pharmacokinetic interactions between sirolimus and cyclosporine exacerbate renal dysfunction.
Journal: Transplantation proceedings 20010101
Title: Fast quantification method for sirolimus and its major metabolites.
Journal: Transplantation proceedings 20010101
Title: Impact of sirolimus on renal transplant outcomes in African Americans.
Journal: Transplantation proceedings 20010101
Title: Sirolimus permits steroid withdrawal from a cyclosporine regimen.
Journal: Transplantation proceedings 20010101
Title: Therapeutic drug monitoring of sirolimus for optimal renal transplant outcomes.
Journal: Transplantation proceedings 20010101
Title: De novo use of low-dose tacrolimus and sirolimus in liver transplantation.
Journal: Transplantation proceedings 20010101
Title: Sirolimus (rapamycin)-based rescue treatment following chronic rejection after liver transplantation.
Journal: Transplantation proceedings 20010101
Title: Rapamycin blocks IL-2-driven T cell cycle progression while preserving T cell survival.
Journal: Blood cells, molecules & diseases 20010101
Title: Influence of cyclosporin, tacrolimus and rapamycin on renal function and arterial hypertension after renal transplantation.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101
Title: Rapamycin reduces hybridoma cell death and enhances monoclonal antibody production.
Journal: Biotechnology and bioengineering 20010101
Title: High-throughput semi-automated 96-well liquid/liquid extraction and liquid chromatography/mass spectrometric analysis of everolimus (RAD 001) and cyclosporin a (CsA) in whole blood.
Journal: Rapid communications in mass spectrometry : RCM 20010101
Title: Protein tyrosine kinase-dependent regulation of adenylate cyclase and phosphatidylinositol 3-kinase activates the expression of glial fibrillary acidic protein upon induction of differentiation in rat c6 glioma.
Journal: Cell biology international 20010101
Title: Methods and assays to investigate nuclear export.
Journal: Current topics in microbiology and immunology 20010101
Title: HPLC assay with ultraviolet detection for therapeutic drug monitoring of sirolimus.
Journal: Clinical chemistry 20010101
Title: A new vascularized adrenal transplantation model in the rat.
Journal: Microsurgery 20010101
Title: Adverse gastrointestinal effects of mycophenolate mofetil: aetiology, incidence and management.
Journal: Drug safety 20010101
Title: Clinical pharmacokinetics of sirolimus.
Journal: Clinical pharmacokinetics 20010101
Title: Control of translation by the target of rapamycin proteins.
Journal: Progress in molecular and subcellular biology 20010101
Title: Regulation of protein synthesis by insulin through IRS-1.
Journal: Progress in molecular and subcellular biology 20010101
Title: The evolving role of tor inhibitors for individualizing posttransplant immunosuppression.
Journal: Transplantation proceedings 20010101
Title: Abbreviated cyclosporine pharmacokinetic profiling in clinical renal transplantation: from principles to practice.
Journal: Transplantation proceedings 20010101
Title: The role of Certican (everolimus, rad) in the many pathways of chronic rejection.
Journal: Transplantation proceedings 20010101
Title: Rapamycin reduces rejection in heart transplant recipients.
Journal: Transplantation proceedings 20010101
Title: Sirolimus and low-dose tacrolimus with antibody induction in kidney transplantation: preliminary results of a pilot study.
Journal: Transplantation proceedings 20010101
Title: Low-dose sirolimus and tacrolimus in kidney transplantation: first results of a single-center experience.
Journal: Transplantation proceedings 20010101
Title: Low-dose immunosuppression with FK 506 and sirolimus after liver transplantation: 1-year results.
Journal: Transplantation proceedings 20010101
Title: A pilot study of steroid withdrawal from kidney transplant recipients on sirolimus-cyclosporine a combination therapy.
Journal: Transplantation proceedings 20010101
Title: Conversion to rapamycin in renal allograft recipients with biopsy-proven calcineurin inhibitor-induced nephrotoxicity.
Journal: Transplantation proceedings 20010101
Title: De novo hemolytic uremic syndrome after kidney transplantation in patients treated with cyclosporine a sirolimus combination.
Journal: Transplantation proceedings 20010101
Title: Effect of ERL080A, RAD, and Neoral on hamster-to-rat heart xenograft survival.
Journal: Transplantation proceedings 20010101
Title: Stent development and local drug delivery.
Journal: British medical bulletin 20010101
Title: [New developments in immunosuppressive therapy].
Journal: Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress 20010101
Title: Resistance to rapamycin: a novel anticancer drug.
Journal: Cancer metastasis reviews 20010101
Title: [Toward an evidence-based immunosuppression].
Journal: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20010101
Title: Secondary metabolism in simulated microgravity.
Journal: Chemical record (New York, N.Y.) 20010101
Title: Anaerobic growth of Saccharomyces cerevisiae alleviates the lethal effect of phosphotyrosyl phosphatase activators depletion.
Journal: Acta biochimica Polonica 20010101
Title: The drug-eluting stent: is it the Holy Grail?
Journal: Reviews in cardiovascular medicine 20010101
Title: Conversion to rapamycin immunosuppression in renal transplant recipients: report of an initial experience.
Journal: Transplantation 20001027
Title: Specificity and mechanism of action of some commonly used protein kinase inhibitors.
Journal: The Biochemical journal 20001001
Title: Endothelin-1 as a protective factor against beta-adrenergic agonist-induced apoptosis in cardiac myocytes.
Journal: Journal of the American College of Cardiology 20001001
Title: Stem cell factor/c-kit up-regulates cyclin D3 and promotes cell cycle progression via the phosphoinositide 3-kinase/p70 S6 kinase pathway in spermatogonia.
Journal: The Journal of biological chemistry 20000818
Title: Antifungal rapamycin analogues with reduced immunosuppressive activity.
Journal: Bioorganic & medicinal chemistry letters 20000703
Title: Sirolimus: a new agent for prevention of renal allograft rejection.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20000301
Title: Sirolimus in pediatric gastrointestinal transplantation: the use of sirolimus for pediatric transplant patients with tacrolimus-related cardiomyopathy.
Journal: Pediatric transplantation 20000201
Title: Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis.
Journal: Gastroenterology 19991101
Title: A phase I study of a 4-week course of SDZ-RAD (RAD) quiescent cyclosporine-prednisone-treated renal transplant recipients.
Journal: Transplantation 19991027
Title: Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action.
Journal: Clinical microbiology reviews 19991001
Title: Cellular stress in xenopus kidney cells enhances the phosphorylation of eukaryotic translation initiation factor (eIF)4E and the association of eIF4F with poly(A)-binding protein.
Journal: The Biochemical journal 19990915
Title: Neuronal survival activity of s100betabeta is enhanced by calcineurin inhibitors and requires activation of NF-kappaB.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19990901
Title: p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes.
Journal: Molecular and cellular biology 19990701
Title: Rapamycin inhibits didemnin B-induced apoptosis in human HL-60 cells: evidence for the possible involvement of FK506-binding protein 25.
Journal: Immunology and cell biology 19990601
Title: Systemic toxicity following administration of sirolimus (formerly rapamycin) for psoriasis: association of capillary leak syndrome with apoptosis of lesional lymphocytes.
Journal: Archives of dermatology 19990501
Title: Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine. Sirolimus European Renal Transplant Study Group.
Journal: Transplantation 19990415
Title: The FKBP12-rapamycin-binding domain is required for FKBP12-rapamycin-associated protein kinase activity and G1 progression.
Journal: The Journal of biological chemistry 19990212
Title: Immunophilins: beyond immunosuppression.
Journal: Journal of medicinal chemistry 19981217
Title: Regulation of System A amino acid transport in L6 rat skeletal muscle cells by insulin, chemical and hyperthermic stress.
Journal: FEBS letters 19981211
Title: Expression and regulation of neuronal apoptosis inhibitory protein during adipocyte differentiation.
Journal: Diabetes 19981201
Title: Ascomycin macrolactam derivative SDZ ASM 981 inhibits the release of granule-associated mediators and of newly synthesized cytokines in RBL 2H3 mast cells in an immunophilin-dependent manner.
Journal: Archives of dermatological research 19980901
Title: Chemical modification of rapamycin: the discovery of SDZ RAD.
Journal: Transplantation proceedings 19980801
Title: Protective effects of FK506 against glutamate-induced neurotoxicity in retinal cell culture.
Journal: Investigative ophthalmology & visual science 19980601
Title: Antifungal activities of rapamycin and its derivatives, prolylrapamycin, 32-desmethylrapamycin, and 32-desmethoxyrapamycin.
Journal: The Journal of antibiotics 19980501
Title: Radiosensitization of human tumor cells by the phosphatidylinositol3-kinase inhibitors wortmannin and LY294002 correlates with inhibition of DNA-dependent protein kinase and prolonged G2-M delay.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 19970701
Title: Rapamycin (sirolimus) inhibits proliferating cell nuclear antigen expression and blocks cell cycle in the G1 phase in human keratinocyte stem cells.
Journal: The Journal of clinical investigation 19970501
Title: Novel anti-Pneumocystis carinii effects of the immunosuppressant mycophenolate mofetil in contrast to provocative effects of tacrolimus, sirolimus, and dexamethasone.
Journal: The Journal of infectious diseases 19970401
Title: Sirolimus, a new, potent immunosuppressive agent.
Journal: Pharmacotherapy 19970101
Title: Rapamycin stimulates viral protein synthesis and augments the shutoff of host protein synthesis upon picornavirus infection.
Journal: Journal of virology 19961201
Title: Comparison of acute rapamycin nephrotoxicity with cyclosporine and FK506.
Journal: Kidney international 19961001
Title: Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation.
Journal: The EMBO journal 19960201
Title: Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.
Journal: Molecular pharmacology 19960201
Title: Rapamycin inhibits the in vitro release of soluble interleukin-2 receptor by activated peripheral blood mononuclear cells (PBMC) independently of the mode of activation.
Journal: International journal of immunopharmacology 19950701
Title: Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19950523
Title: Rapamycin-FKBP inhibits cell cycle regulators of proliferation in vascular smooth muscle cells.
Journal: Circulation research 19950301
Title: Nephrotoxicity of cyclosporin A and FK506: inhibition of calcineurin phosphatase.
Journal: Renal physiology and biochemistry 19950101
Title: RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19941220
Title: Nephrotoxicity of immunosuppressants in rats: comparison of macrolides with cyclosporin.
Journal: Experimental nephrology 19940101
Title: Rapamycin-FKBP12 blocks proliferation, induces differentiation, and inhibits cdc2 kinase activity in a myogenic cell line.
Journal: The Journal of biological chemistry 19931205
Title: Rapamycin blocks cell cycle progression of activated T cells prior to events characteristic of the middle to late G1 phase of the cycle.
Journal: Journal of cellular physiology 19930101
Title: Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype.
Journal: Blood 19920915
Title: Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase.
Journal: Nature 19920702
Title: Rapamycin and FK506 differentially inhibit mast cell cytokine production and cytokine-induced proliferation and act as reciprocal antagonists.
Journal: The Journal of pharmacology and experimental therapeutics 19920601
Title: Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19920501
Title: Effects of steroids and immunosuppressive drugs on endotoxin-uveitis in rabbits.
Journal: Journal of ocular pharmacology 19920101
Title: Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes.
Journal: Cell 19910823
Title: The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation.
Journal: European journal of immunology 19910201
Title: Calcineurin primes immature gonadotropin-releasing hormone-secreting neuroendocrine cells for migration.
Journal: Molecular endocrinology (Baltimore, Md.)
Title: Chronic inhibition of the mTORC1/S6K1 pathway increases insulin-induced PI3K activity but inhibits Akt2 and glucose transport stimulation in 3T3-L1 adipocytes.
Journal: Molecular endocrinology (Baltimore, Md.)
