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15966-93-5,MFCD04974538
Catalog No.:AA001R8A

15966-93-5 | 1H-Pyrrole-3-carboxylic acid, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-, ethyl ester

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$92.00   $64.00
- +
5mg
98%
in stock  
$233.00   $163.00
- +
10mg
98%
in stock  
$321.00   $225.00
- +
25mg
98%
in stock  
$544.00   $381.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA001R8A
Chemical Name:
1H-Pyrrole-3-carboxylic acid, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-, ethyl ester
CAS Number:
15966-93-5
Molecular Formula:
C18H18N2O3
Molecular Weight:
310.3471
MDL Number:
MFCD04974538
SMILES:
CCOC(=O)c1c(C)[nH]c(c1C)C=C1C(=O)Nc2c1cccc2
Properties
Computed Properties
 
Complexity:
516  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
1  
XLogP3:
2.7  

Downstream Synthesis Route
Literature

Title: t(8;21) acute myeloid leukaemia cells are dependent on vascular endothelial growth factor (VEGF)/VEGF receptor type2 pathway and phosphorylation of Akt.

Journal: British journal of haematology 20061201

Title: Synthesis and biological evaluations of 3-substituted indolin-2-ones: a novel class of tyrosine kinase inhibitors that exhibit selectivity toward particular receptor tyrosine kinases.

Journal: Journal of medicinal chemistry 19980702

Title: Sun L, et al. Synthesis and biological evaluations of 3-substituted indolin-2-ones: a novel class of tyrosine kinase inhibitors that exhibit selectivity towardparticular receptor tyrosine kinases. J Med Chem. 1998 Jul 2;41(14):2588-603.

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SDS
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Tags:15966-93-5 Molecular Formula|15966-93-5 MDL|15966-93-5 SMILES|15966-93-5 1H-Pyrrole-3-carboxylic acid, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-, ethyl ester
Catalog No.: AA001R8A
15966-93-5,MFCD04974538
15966-93-5 | 1H-Pyrrole-3-carboxylic acid, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-, ethyl ester
Pack Size： 1mg
Purity： 98%
in stock
$92.00 $64.00
Pack Size： 5mg
Purity： 98%
in stock
$233.00 $163.00
Pack Size： 10mg
Purity： 98%
in stock
$321.00 $225.00
Pack Size： 25mg
Purity： 98%
in stock
$544.00 $381.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA001R8A
Chemical Name: 1H-Pyrrole-3-carboxylic acid, 5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-, ethyl ester
CAS Number: 15966-93-5
Molecular Formula: C18H18N2O3
Molecular Weight: 310.3471
MDL Number: MFCD04974538
SMILES: CCOC(=O)c1c(C)[nH]c(c1C)C=C1C(=O)Nc2c1cccc2
Properties
Complexity: 516  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 23  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 4  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 1  
XLogP3: 2.7  
Downstream Synthesis Route
Literature fold

Title: t(8;21) acute myeloid leukaemia cells are dependent on vascular endothelial growth factor (VEGF)/VEGF receptor type2 pathway and phosphorylation of Akt.

Journal: British journal of haematology20061201

Title: Synthesis and biological evaluations of 3-substituted indolin-2-ones: a novel class of tyrosine kinase inhibitors that exhibit selectivity toward particular receptor tyrosine kinases.

Journal: Journal of medicinal chemistry19980702

Title: Sun L, et al. Synthesis and biological evaluations of 3-substituted indolin-2-ones: a novel class of tyrosine kinase inhibitors that exhibit selectivity towardparticular receptor tyrosine kinases. J Med Chem. 1998 Jul 2;41(14):2588-603.

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