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Home Other Building Blocks 16006-64-7
16006-64-7,MFCD29059892
Catalog No.:AA00ACDT

16006-64-7 | 6-methylpurine 2'-deoxyriboside

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
95%
in stock  
$268.00   $188.00
- +
50mg
95%
in stock  
$839.00   $588.00
- +
250mg
95%
in stock  
$2,554.00   $1,788.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ACDT
Chemical Name:
6-methylpurine 2'-deoxyriboside
CAS Number:
16006-64-7
Molecular Formula:
C11H14N4O3
Molecular Weight:
250.2539
MDL Number:
MFCD29059892
SMILES:
OCC1OC(CC1O)n1cnc2c1ncnc2C
Properties
Computed Properties
 
Complexity:
306  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
0.2  

Literature

Title: Synthesis and evaluation of the substrate activity of C-6 substituted purine ribosides with E. coli purine nucleoside phosphorylase: palladium mediated cross-coupling of organozinc halides with 6-chloropurine nucleosides.

Journal: European journal of medicinal chemistry 20120101

Title: Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase.

Journal: Cancer gene therapy 20110601

Title: Enzymatic synthesis of 2'-deoxyadenosine and 6-methylpurine-2'-deoxyriboside by Escherichia coli DH5alpha overexpressing nucleoside phosphorylases from Escherichia coli BL21.

Journal: Journal of bioscience and bioengineering 20100801

Title: Synergistic antitumor efficacy of suicide/ePNP gene and 6-methylpurine 2'-deoxyriboside via Salmonella against murine tumors.

Journal: Cancer gene therapy 20080701

Title: hTERT-targeted E. coli purine nucleoside phosphorylase gene/6-methylpurine deoxyribose therapy for pancreatic cancer.

Journal: Chinese medical journal 20070805

Title: [Killing effect of PNP/MeP-dR suicide gene system driven by an AFP promoter AF0.3 on AFP-positive hepatoma cells].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20061101

Title: Transcriptional tumor-selective promoter targeting of E. coli purine nucleoside phosphorylase for pancreatic cancer suicide gene therapy.

Journal: The journal of gene medicine 20050501

Title: Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus-based glioma therapy.

Journal: Human gene therapy 20050301

Title: PNP anticancer gene therapy.

Journal: Current topics in medicinal chemistry 20050101

Title: Suicide gene/prodrug therapy for pancreatic adenocarcinoma by E. coli purine nucleoside phosphorylase and 6-methylpurine 2'-deoxyriboside.

Journal: Pancreas 20040301

Title: A long-acting suicide gene toxin, 6-methylpurine, inhibits slow growing tumors after a single administration.

Journal: The Journal of pharmacology and experimental therapeutics 20030301

Title: Antitumor activity of 2-fluoro-2'-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase.

Journal: Cancer gene therapy 20030101

Title: Current progress in suicide gene therapy for cancer.

Journal: World journal of surgery 20020701

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SDS
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