+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Other Building Blocks 14675-48-0
14675-48-0,MFCD00056009
Catalog No.:AA007XYL

14675-48-0 | (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)tetrahydrofuran-3,4-diol

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
98%
in stock  
$378.00   $264.00
- +
1g
98%
in stock  
$926.00   $648.00
- +
5g
98%
in stock  
$4,417.00   $3,092.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA007XYL
Chemical Name:
(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)tetrahydrofuran-3,4-diol
CAS Number:
14675-48-0
Molecular Formula:
C11H14N4O4
Molecular Weight:
266.2533
MDL Number:
MFCD00056009
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2C
Properties
Computed Properties
 
Complexity:
334  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
-0.3  

Literature

Title: Synthesis and evaluation of the substrate activity of C-6 substituted purine ribosides with E. coli purine nucleoside phosphorylase: palladium mediated cross-coupling of organozinc halides with 6-chloropurine nucleosides.

Journal: European journal of medicinal chemistry 20120101

Title: Synthesis of a 6-methyl-7-deaza analogue of adenosine that potently inhibits replication of polio and dengue viruses.

Journal: Journal of medicinal chemistry 20101125

Title: Atomic mutagenesis reveals A2660 of 23S ribosomal RNA as key to EF-G GTPase activation.

Journal: Nature chemical biology 20100501

Title: Regioselective metalation of 6-methylpurines: synthesis of fluoromethyl purines and related nucleosides for suicide gene therapy of cancer.

Journal: Nucleosides, nucleotides & nucleic acids 20090501

Title: Cytostatic and antiviral 6-arylpurine ribonucleosides. Part 7: synthesis and evaluation of 6-substituted purine l-ribonucleosides.

Journal: Bioorganic & medicinal chemistry letters 20061015

Title: An efficient synthesis of 2-substituted 6-methylpurine bases and nucleosides by Fe- or Pd-catalyzed cross-coupling reactions of 2,6-dichloropurines.

Journal: The Journal of organic chemistry 20030711

Title: Antiviral activity of C-alkylated purine nucleosides obtained by cross-coupling with tetraalkyltin reagents.

Journal: Journal of medicinal chemistry 19931001

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 14675-48-0
39007-51-7

39007-51-7

 16006-64-7

16006-64-7

 550-33-4

550-33-4

 690269-86-4

690269-86-4

 690269-86-4

690269-86-4

 1612191-88-4

1612191-88-4
Building Blocks
More >
Tags:14675-48-0 Molecular Formula|14675-48-0 MDL|14675-48-0 SMILES|14675-48-0 (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-methyl-9H-purin-9-yl)tetrahydrofuran-3,4-diol