Catalog No.:AA01ENHX

1609937-15-6 | Mambalgin 1

Name: Name:Mambalgin 1
Brand: AABLOCKS
SKU: AA01ENHX
Rating: 90 (10 reviews)

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Technical Information
Properties
Literature
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Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA01ENHX

Chemical Name:

Mambalgin 1

CAS Number:

1609937-15-6

Molecular Formula:

C272H429N85O84S9

Molecular Weight:

6522.4208

SMILES:

NCCCCC1NC(=O)CNC(=O)C(Cc2c[nH]cn2)NC(=O)C(CCC(=O)N)NC(=O)C(Cc2ccc(cc2)O)NC(=O)C(CSCC2NC(=O)C(Cc3ccccc3)NC(=O)C(CCCCN)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)C(C)C)C(C)C)C(O)C)CSSCC(NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)N)NC(=O)C(NC(=O)C(NC(=O)C1N(C(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)Cc2ccc(cc2)O)Cc2c[nH]cn2)CC(=O)N)C(O)C)CCSC)CCC1)Cc1ccccc1)CCCNC(=N)N)C(CC)C)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC1CSSCC(NC(=O)C(CCCCN)NC(=O)C(CC(=O)N)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CO)CCC(=O)O)C(O)C)CCC(=O)O)CC(=O)N)C(=O)NC1CSSCC(NC(=O)C(CCCNC(=N)N)NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CO)C(O)C)CC(=O)O)C(=O)NC(C(=O)NC(C(=O)O)CCCCN)CC(=O)N)CO)CO)CO)Cc1c[nH]cn1)CCCNC(=N)N)CC(=O)O)CCSC)NC(=O)C(NC(=O)C(CC(C)C)N)CCCCN

Properties

Literature

Title: Sun D, et al. Cryo-EM structure of the ASIC1a-mambalgin-1 complex reveals that the peptide toxin mambalgin-1 inhibits acid-sensing ion channels through an unusual allosteric effect. Cell Discov. 2018;4:27. Published 2018 Jun 5.

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