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1613439-62-5,MFCD24387542
Catalog No.:AA00AT7D

1613439-62-5 | PF-05274857 HCl

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥98%(HPLC)
in stock  
$263.00   $184.00
- +
10mg
≥98%(HPLC)
in stock  
$372.00   $260.00
- +
25mg
≥98%(HPLC)
in stock  
$765.00   $535.00
- +
50mg
≥98%(HPLC)
in stock  
$1,381.00   $967.00
- +
100mg
≥98%(HPLC)
in stock  
$2,438.00   $1,707.00
- +
  • Technical Information
  • Properties
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00AT7D
Chemical Name:
PF-05274857 HCl
CAS Number:
1613439-62-5
Molecular Formula:
C20H26Cl2N4O3S
Molecular Weight:
473.4164
MDL Number:
MFCD24387542
SMILES:
Cc1cnc(c(c1)C)c1cc(ncc1Cl)N1CCN(CC1)C(=O)CCS(=O)(=O)C.Cl
Properties
Computed Properties
 
Complexity:
663  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  

Literature

Title: Rohner A, et, al. Effective targeting of Hedgehog signaling in a medulloblastoma model with PF-5274857, a potent and selective Smoothened antagonist that penetrates the blood-brain barrier. Mol Cancer Ther. 2012 Jan;11(1):57-65.

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SDS
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Tags:1613439-62-5 Molecular Formula|1613439-62-5 MDL|1613439-62-5 SMILES|1613439-62-5 PF-05274857 HCl