Home Imidazoles 1616632-77-9
1616632-77-9,MFCD28118993
Catalog No.:AA001VPM

1616632-77-9 | 7-Benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4h)-one

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
99+%
in stock  
$13.00   $9.00
- +
5mg
99+%
in stock  
$36.00   $25.00
- +
10mg
99+%
in stock  
$46.00   $32.00
- +
25mg
99+%
in stock  
$58.00   $41.00
- +
50mg
99+%
in stock  
$75.00   $53.00
- +
100mg
99+%
in stock  
$97.00   $68.00
- +
250mg
99+%
in stock  
$162.00   $114.00
- +
1g
99+%
in stock  
$425.00   $298.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001VPM
Chemical Name:
7-Benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4h)-one
CAS Number:
1616632-77-9
Molecular Formula:
C24H26N4O
Molecular Weight:
386.4894
MDL Number:
MFCD28118993
SMILES:
Cc1ccccc1Cn1c(=O)c2CN(CCc2n2c1=NCC2)Cc1ccccc1
Properties
Computed Properties
 
Complexity:
693  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
4  
XLogP3:
2.3  

Literature

Title: Dose intensification of TRAIL-inducing ONC201 inhibits metastasis and promotes intratumoral NK cell recruitment.

Journal: The Journal of clinical investigation 20180601

Title: Discovery and clinical introduction of first-in-class imipridone ONC201.

Journal: Oncotarget 20161108

Title: Dual inactivation of Akt and ERK by TIC10 signals Foxo3a nuclear translocation, TRAIL gene induction, and potent antitumor effects.

Journal: Science translational medicine 20130206

Title: Allen JE, et al. Dual inactivation of Akt and ERK by TIC10 signals Foxo3a nuclear translocation, TRAIL gene induction, and potent antitumor effects. Sci Transl Med. 2013 Feb 6;5(171):171ra17.

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SDS
Tags:1616632-77-9 Molecular Formula|1616632-77-9 MDL|1616632-77-9 SMILES|1616632-77-9 7-Benzyl-4-(2-methylbenzyl)-1,2,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4h)-one