Home Amines 161804-20-2
161804-20-2,MFCD12910437
Catalog No.:AA00ALUP

161804-20-2 | 3,5-Diamino-N-(N-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥98%
in stock  
$62.00   $43.00
- +
10mg
≥98%
in stock  
$122.00   $85.00
- +
50mg
≥98%(HPLC)
in stock  
$607.00   $425.00
- +
100mg
≥98%(HPLC)
in stock  
$1,032.00   $723.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ALUP
Chemical Name:
3,5-Diamino-N-(N-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide hydrochloride
CAS Number:
161804-20-2
Molecular Formula:
C13H15Cl2N7O
Molecular Weight:
356.2105
MDL Number:
MFCD12910437
SMILES:
N=C(NC(=O)c1nc(Cl)c(nc1N)N)NCc1ccccc1.Cl
Properties
Computed Properties
 
Complexity:
413  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
4  

Literature

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.

Journal: Antimicrobial agents and chemotherapy 20100901

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Polyadenylated RNA from Vicia faba meristematic root cells. Localization and size estimation of the poly (A) segment.

Journal: European journal of biochemistry 19751201

Title: Fischer KG, et al. Characterization of a Na(+)-Ca(2+) exchanger in podocytes. Nephrol Dial Transplant. 2002 Oct;17(10):1742-50.

Title: Wang X, et al. Effects of amiloride, benzamil, and alterations in extracellular Na+ on the rat afferent arteriole and its myogenic response. Am J Physiol Renal Physiol. 2008 Jul;295(1):F272-82.

Title: Dai XQ, et al. Inhibition of TRPP3 channel by amiloride and analogs. Mol Pharmacol. 2007 Dec;72(6):1576-85.

Title: Castañeda MS, et al. Benzamil inhibits neuronal and heterologously expressed small conductance Ca2+-activated K+channels. Neuropharmacology. 2019 Nov 1;158:107738.

Title: Teiwes J, et al. Epithelial sodium channel inhibition in cardiovascular disease. A potential role for amiloride. Am J Hypertens. 2007 Jan;20(1):109-17.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:161804-20-2 Molecular Formula|161804-20-2 MDL|161804-20-2 SMILES|161804-20-2 3,5-Diamino-N-(N-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide hydrochloride