Home Amines 1622-57-7
1622-57-7,MFCD00142855
Catalog No.:AA001ST9

1622-57-7 | 2-Amino-1-methylbenzimidazole

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250mg
98%
in stock  
$12.00   $8.00
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1g
98%
in stock  
$23.00   $16.00
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5g
98%
in stock  
$103.00   $73.00
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25g
98%
in stock  
$469.00   $328.00
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100g
98%
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$1,808.00   $1,266.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001ST9
Chemical Name:
2-Amino-1-methylbenzimidazole
CAS Number:
1622-57-7
Molecular Formula:
C8H9N3
Molecular Weight:
147.1772
MDL Number:
MFCD00142855
SMILES:
Cn1c(N)nc2c1cccc2
Properties
Properties
 
BP:
334.9°C at 760 mmHg  
Form:
Solid  
MP:
203-206 °C  
Refractive Index:
1.5400 (estimate)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
148  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
XLogP3:
0.9  

Downstream Synthesis Route

[1]CurrentPatentAssignee:ANEOCHEM-TECHCOLTD-CN108912095,2018,ALocationinpatent:Paragraph0194;0198;0199

[2]Avery,VickyM.;Baell,Jonathan;McNamara,Nicole;Rahmani,Raphael;Sykes,MelissaL.[2020,vol.11,#6,p.685-695]

[3]Kikugawa,Yasuo[Synthesis,1981,#2,p.124-125]

[4]CurrentPatentAssignee:GLENMARKPHARMACEUTICALSLTD-US2009/286811,2009,A1Locationinpatent:Page/Pagecolumn21

[5]Locationinpatent:experimentalpartCoetzee,Jacorien;Cronje,Stephanie;Dobrzanska,Liliana;Raubenheimer,HelgardG.;Joone,Gisela;Nell,MargoJ.;Hoppe,HeinrichC.[DaltonTransactions,2011,vol.40,#7,p.1471-1483]

[6]Kaipnazarov;Mukhamedov;Okmanov;Berdimbetova;Zhonkhozhaeva[RussianJournalofOrganicChemistry,2013,vol.49,#12,p.1744-1747][Zh.Org.Khim.,2013,vol.49,#12,p.1764-1767,4]

[1]DaSettimo;Primofiore;DaSettimo;Calzolari;Cazzulani;Passoni;Tofanetti[EuropeanJournalofMedicinalChemistry,1992,vol.27,#4,p.395-400]

619-41-0    1622-57-7   
1-methyl-2-amino-3-(p-toluoylmethyl)benzimidazoliumbromide 

[1]Anisimova,V.A.;Korochina,T.B.;Zhurkina,L.I.[ChemistryofHeterocyclicCompounds,1987,vol.23,#11,p.1195-1201][KhimiyaGeterotsiklicheskikhSoedinenii,1987,#11,p.1496-1502]

[1]Podanyi,Benjamin;Hermecz,Istvan;Horvath,Agnes[JournalofOrganicChemistry,1986,vol.51,#15,p.2988-2994]

[1]Anisimova,V.A.;Levchenko,M.V.;Pozharskii,A.F.[ChemistryofHeterocyclicCompounds,1986,vol.22,#7,p.732-739][KhimiyaGeterotsiklicheskikhSoedinenii,1986,vol.22,#7,p.918-925]

Literature

Title: Removal of nonspecific binding proteins from cell and tissue extracts using 2-aminobenzimidazole-tethered affinity resin.

Journal: Die Pharmazie 20110901

Title: Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1.

Journal: Frontiers in pharmacology 20110101

Title: Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors.

Journal: The Biochemical journal 20101001

Title: Bis(acetyl-acetonato-κO,O')(2-amino-1-methyl-1H-benzimidazole-κN)oxido-vanadium(IV).

Journal: Acta crystallographica. Section E, Structure reports online 20090701

Title: Synthesis, IR, UV/vis-, (1)H NMR and DFT study of chelatophore functionalized 1,3-benzoxazinone spiropyrans.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081201

Title: Unusual solvent effect on a SN2 reaction. A quantum-mechanical and kinetic study of the Menshutkin reaction between 2-amino-1-methylbenzimidazole and iodomethane in the gas phase and in acetonitrile.

Journal: The journal of physical chemistry. B 20060202

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

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Tags:1622-57-7 Molecular Formula|1622-57-7 MDL|1622-57-7 SMILES|1622-57-7 2-Amino-1-methylbenzimidazole |Heterocyclic_Building_Blocks