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163521-08-2,MFCD00940014
Catalog No.:AA001U4C

163521-08-2 | Vilazodone hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
98%
in stock  
$30.00   $21.00
- +
1g
98%
in stock  
$69.00   $48.00
- +
5g
98%
in stock  
$229.00   $160.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001U4C
Chemical Name:
Vilazodone hydrochloride
CAS Number:
163521-08-2
Molecular Formula:
C26H28ClN5O2
Molecular Weight:
477.9858
MDL Number:
MFCD00940014
SMILES:
N#Cc1ccc2c(c1)c(CCCCN1CCN(CC1)c1ccc3c(c1)cc(o3)C(=O)N)c[nH]2.Cl
Properties
Computed Properties
 
Complexity:
729  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
7  

Literature

Title: A review of current evidence for vilazodone in major depressive disorder.

Journal: International journal of psychiatry in clinical practice 20130801

Title: Evidence for the use of vilazodone in the treatment of major depressive disorder.

Journal: Expert opinion on pharmacotherapy 20121001

Title: Vilazodone for the treatment of major depressive disorder.

Journal: Pharmacotherapy 20121001

Title: Vilazodone's comparative merits yet to be demonstrated.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120915

Title: Vilazodone: a novel antidepressant.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120915

Title: Vilazodone for major depressive disorder: a systematic review of the efficacy and safety profile for this newly approved antidepressant - what is the number needed to treat, number needed to harm and likelihood to be helped or harmed?

Journal: International journal of clinical practice 20120401

Title: New drugs 2012 part I.

Journal: Nursing 20120301

Title: The efficacy profile of vilazodone, a novel antidepressant for the treatment of major depressive disorder.

Journal: Current medical research and opinion 20120101

Title: Selective serotonin reuptake inhibitors (SSRIs): therapeutic drug monitoring and pharmacological interactions.

Journal: Current medicinal chemistry 20120101

Title: A 1-year, open-label study assessing the safety and tolerability of vilazodone in patients with major depressive disorder.

Journal: Journal of clinical psychopharmacology 20111001

Title: Vilazodone: clinical basis for the US Food and Drug Administration's approval of a new antidepressant.

Journal: The Journal of clinical psychiatry 20110901

Title: A new antidepressant.

Journal: Behavioral healthcare 20110901

Title: Vilazodone (Viibryd)--a new antidepressant.

Journal: The Medical letter on drugs and therapeutics 20110711

Title: Vilazodone for the treatment of depression.

Journal: The Annals of pharmacotherapy 20110701

Title: Vilazodone: in major depressive disorder.

Journal: CNS drugs 20110701

Title: Vilazodone: a new treatment option for major depressive disorder.

Journal: Drugs of today (Barcelona, Spain : 1998) 20110701

Title: A randomized, double-blind, placebo-controlled, 8-week study of vilazodone, a serotonergic agent for the treatment of major depressive disorder.

Journal: The Journal of clinical psychiatry 20110401

Title: Vilazodone: another novel atypical antidepressant drug.

Journal: Journal of psychosocial nursing and mental health services 20110301

Title: Vilazodone approved for major depression.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110301

Title: Vilazodone hydrochloride, linagliptin, and alcaftadine.

Journal: Journal of the American Pharmacists Association : JAPhA 20110101

Title: Vilazodone, a novel dual-acting serotonergic antidepressant for managing major depression.

Journal: Expert opinion on investigational drugs 20091101

Title: Evidence for efficacy and tolerability of vilazodone in the treatment of major depressive disorder: a randomized, double-blind, placebo-controlled trial.

Journal: The Journal of clinical psychiatry 20090301

Title: Vilazodone: a 5-HT1A receptor agonist/serotonin transporter inhibitor for the treatment of affective disorders.

Journal: CNS neuroscience & therapeutics 20090101

Title: Drug evaluation: Vilazodone--a combined SSRI and 5-HT1A partial agonist for the treatment of depression.

Journal: IDrugs : the investigational drugs journal 20070301

Title: Effect of vilazodone on 5-HT efflux and re-uptake in the guinea-pig dorsal raphe nucleus.

Journal: European journal of pharmacology 20050704

Title: Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone.

Journal: European journal of pharmacology 20050307

Title: Effects of systemic injections of vilazodone, a selective serotonin reuptake inhibitor and serotonin 1A receptor agonist, on anxiety induced by predator stress in rats.

Journal: European journal of pharmacology 20041103

Title: Dual 5-HT1A agonists and 5-HT re-uptake inhibitors by combination of indole-butyl-amine and chromenonyl-piperazine structural elements in a single molecular entity.

Journal: Bioorganic & medicinal chemistry 20040915

Title: A new synthesis of indole 5-carboxylic acids and 6-hydroxy-indole-5-carboxylic acids in the preparation of an o-hydroxylated metabolite of vilazodone.

Journal: Bioorganic & medicinal chemistry letters 20040517

Title: Phase I and II enzyme characterization of two sources of HepG2 cell lines.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040301

Title: Behavioral and neurochemical effects of 5-(4-[4-(5-Cyano-3-indolyl)-butyl)-butyl]-1-piperazinyl)-benzofuran-2-carboxamide (EMD 68843): a combined selective inhibitor of serotonin reuptake and 5-hydroxytryptamine(1A) receptor partial agonist.

Journal: The Journal of pharmacology and experimental therapeutics 20020901

Title: Distinct temporal pattern of the effects of the combined serotonin-reuptake inhibitor and 5-HT1A agonist EMD 68843 on the sleep EEG in healthy men.

Journal: Psychopharmacology 20010501

Title: Systemic EMD 68843 injections reduce anxiety in the shock-probe, but not the plus-maze test.

Journal: European journal of pharmacology 20010302

Title: Lee A. Dawson et al. Vilazodone: A 5-HT1A Receptor Agonist/Serotonin Transporter Inhibitor for the Treatment of Affective Disorders CNS Neuroscience & Therapeutics Volume 15, Issue 2, pages 107-117, June 2009

Title: Reed CR, Kajdasz DK, Whalen H, Athanasiou MC, Gallipoli S, Thase ME.The efficacy profile of vilazodone, a novel antidepressant for the treatment of major depressive disorder.Curr Med Res Opin. 2012 Jan;28(1):27-39.

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