Home Amines 17094-01-8
17094-01-8,MFCD00210214
Catalog No.:AA003U5V

17094-01-8 | (S)-2-Amino-6-(2-hydroxypropanoyl)-7,8-dihydropteridin-4(3H)-one

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Purity
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1mg
2 weeks  
$726.00   $508.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003U5V
Chemical Name:
(S)-2-Amino-6-(2-hydroxypropanoyl)-7,8-dihydropteridin-4(3H)-one
CAS Number:
17094-01-8
Molecular Formula:
C9H11N5O3
Molecular Weight:
237.2153
MDL Number:
MFCD00210214
SMILES:
C[C@H](C(=O)C1=Nc2c(NC1)[nH]c(nc2=O)N)O
Properties
Properties
 
Form:
Solid  
MP:
>270 °C (dec.)  
Storage:
2-8℃;Inert atmosphere;Light sensitive;  

Computed Properties
 
Complexity:
491  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
2  
XLogP3:
-2  

Literature

Title: Statin-induced inhibition of breast cancer proliferation and invasion involves attenuation of iron transport: intermediacy of nitric oxide and antioxidant defence mechanisms.

Journal: The FEBS journal 20140801

Title: 4-Hydroxy-2-nonenal increases superoxide anion radical in endothelial cells via stimulated GTP cyclohydrolase proteasomal degradation.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20071101

Title: Mechanisms of inducible nitric oxide synthase-mediated vascular dysfunction.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20050801

Title: GTP cyclohydrolase 1 inhibition attenuates vasodilation and increases blood pressure in rats.

Journal: American journal of physiology. Heart and circulatory physiology 20031101

Title: Effect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cells.

Journal: Journal of cardiovascular pharmacology 20010301

Title: Guanosine triphosphate cyclohydrolase I regulates nitric oxide synthesis in renal proximal tubules.

Journal: Journal of the American Society of Nephrology : JASN 19950201

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Tags:17094-01-8 Molecular Formula|17094-01-8 MDL|17094-01-8 SMILES|17094-01-8 (S)-2-Amino-6-(2-hydroxypropanoyl)-7,8-dihydropteridin-4(3H)-one