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17348-76-4,MFCD00017702
Catalog No.:AA001YVB

17348-76-4 | 4H-1-Benzopyran-4-one, 2,3-dihydro-2-(2-hydroxyphenyl)-

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1g
>98.0%(HPLC)
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA001YVB
Chemical Name:
4H-1-Benzopyran-4-one, 2,3-dihydro-2-(2-hydroxyphenyl)-
CAS Number:
17348-76-4
Molecular Formula:
C15H12O3
Molecular Weight:
240.2540
MDL Number:
MFCD00017702
SMILES:
Oc1ccccc1C1CC(=O)c2c(O1)cccc2
Properties
Properties
 
Form:
Solid  
MP:
164.0 to 168.0 °C  

Computed Properties
 
Complexity:
315  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
1  
XLogP3:
2.5  

Literature

Title: C-Glycosyltransferases catalyzing the formation of di-C-glucosyl flavonoids in citrus plants.

Journal: The Plant journal : for cell and molecular biology 20170701

Title: The influence of β-cyclodextrin encapsulation on the binding of 2'-hydroxyflavanone with calf thymus DNA.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121201

Title: 3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic Acids: highly potent and selective inhibitors of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3.

Journal: Journal of medicinal chemistry 20120913

Title: Evaluation of novel amylose and cellulose-based chiral stationary phases for the stereoisomer separation of flavanones by means of nano-liquid chromatography.

Journal: Analytica chimica acta 20120813

Title: 2'-Hydroxyflavanone induces apoptosis through Egr-1 involving expression of Bax, p21, and NAG-1 in colon cancer cells.

Journal: Molecular nutrition & food research 20120501

Title: Aldo-keto reductase 1C3 is expressed in differentiated human epidermis, affects keratinocyte differentiation, and is upregulated in atopic dermatitis.

Journal: The Journal of investigative dermatology 20120401

Title: 2'-hydroxyflavanone inhibits proliferation, tumor vascularization and promotes normal differentiation in VHL-mutant renal cell carcinoma.

Journal: Carcinogenesis 20110401

Title: Optical isomer separation of flavanones and flavanone glycosides by nano-liquid chromatography using a phenyl-carbamate-propyl-beta-cyclodextrin chiral stationary phase.

Journal: Journal of chromatography. A 20100212

Title: Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.

Journal: Bioorganic & medicinal chemistry 20100101

Title: Relationships between the structures of flavanone derivatives and their effects in enhancing early growth response-1 gene expression.

Journal: Bioorganic & medicinal chemistry letters 20090415

Title: Screening of flavonoids as candidate antibiotics against Enterococcus faecalis.

Journal: Journal of natural products 20090401

Title: AKR1C3 as a potential target for the inhibitory effect of dietary flavonoids.

Journal: Chemico-biological interactions 20090316

Title: Discovery of nonsteroidal 17beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries.

Journal: Journal of medicinal chemistry 20080724

Title: Chiral separation of hydroxyflavanones in cyclodextrin-modified capillary zone electrophoresis using sulfated cyclodextrins as chiral selectors.

Journal: Journal of chromatography. A 20080425

Title: [Effects of flavonoids with different structures on proliferation of leukemia cell line HL-60].

Journal: Ai zheng = Aizheng = Chinese journal of cancer 20071201

Title: Flavanone and 2'-OH flavanone inhibit metastasis of lung cancer cells via down-regulation of proteinases activities and MAPK pathway.

Journal: Chemico-biological interactions 20070501

Title: Rapid hepatic metabolism of 7-ketocholesterol by 11beta-hydroxysteroid dehydrogenase type 1: species-specific differences between the rat, human, and hamster enzyme.

Journal: The Journal of biological chemistry 20040430

Title: A rapid screening assay for inhibitors of 11beta-hydroxysteroid dehydrogenases (11beta-HSD): flavanone selectively inhibits 11beta-HSD1 reductase activity.

Journal: Molecular and cellular endocrinology 20031230

Title: Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists.

Journal: Journal of medicinal chemistry 19960607

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Tags:17348-76-4 Molecular Formula|17348-76-4 MDL|17348-76-4 SMILES|17348-76-4 4H-1-Benzopyran-4-one, 2,3-dihydro-2-(2-hydroxyphenyl)- |Organic_Building_Blocks