Home Aldehydes 174634-08-3
174634-08-3,MFCD26960891
Catalog No.:AA00ABJ2

174634-08-3 | Tas-103

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250mg
98%
2 weeks  
$1,871.00   $1,310.00
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  • Technical Information
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Technical Information
Catalog Number:
AA00ABJ2
Chemical Name:
Tas-103
CAS Number:
174634-08-3
Molecular Formula:
C20H19N3O2
Molecular Weight:
333.3838
MDL Number:
MFCD26960891
SMILES:
CN(CCNc1nc2cc(O)ccc2c2c1C(=O)c1c2cccc1)C
Properties

Literature

Title: Padget K, et al. An investigation into the formation of N- -(dimethylamino)ethylacridine-4-carboxamide (DACA) and 6--(dimethylamino)ethylamino- 3-hydroxy-7H-indeno, 1-Cquinolin-7-one dihydrochloride (TAS-103) stabilised DNA topoisomerase I and II cleavable complexes in human leukaemia cells. Biochem Pharmacol. 2000 Sep 15;60(6):817-21.

Title: Shimizu K, et al. Cancer chemotherapy by liposomal 6-2-(dimethylamino)ethylaminol-3-hydroxy-7H-indeno,1-clquinolin-7-one dihydrochloride (TAS-103), a novel anti-cancer agent. Biol Pharm Bull. 2002 Oct;25(10):1385-7.

Title: Yoshida M, et al. A new mechanism of 6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno(2,1-c)quinolin-7-one dihydrochloride (TAS-103) action discovered by target screening with drug-immobilized affinity beads. Mol Pharmacol. 2008 Mar;73(3):987-94. Epub 2007 Dec 18.

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