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Home Other Building Blocks 1799328-86-1
1799328-86-1,MFCD31619274
Catalog No.:AA01EONN

1799328-86-1 | ASTX660

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$63.00   $44.00
- +
5mg
98%
in stock  
$281.00   $197.00
- +
10mg
98%
in stock  
$415.00   $290.00
- +
25mg
98%
in stock  
$772.00   $540.00
- +
50mg
98%
in stock  
$1,199.00   $839.00
- +
100mg
98%
in stock  
$1,681.00   $1,177.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01EONN
Chemical Name:
ASTX660
CAS Number:
1799328-86-1
Molecular Formula:
C30H42FN5O3
Molecular Weight:
539.6846
MDL Number:
MFCD31619274
SMILES:
OCc1nc2c(cc1Cc1ccc(cc1)F)N(CC2(C)C)C(=O)CN1C[C@@H](C)NC[C@@H]1CN1CCOC[C@H]1C
Properties
Computed Properties
 
Complexity:
824  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
39  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
7  
XLogP3:
2.3  

Downstream Synthesis Route

[1]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2015/92420,2015,A1

[1]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2015/92420,2015,A1

[2]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2021/225955,2021,A1

[3]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2021/225955,2021,A1

[1]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2015/92420,2015,A1Locationinpatent:Page/Pagecolumn147

[1]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2015/92420,2015,A1

[1]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2015/92420,2015,A1

[2]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2021/225955,2021,A1

[3]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2021/225955,2021,A1

[4]CurrentPatentAssignee:OTSUKAHOLDINGSCOLTD-WO2021/225955,2021,A1

Literature

Title: Tomoko Smyth, et al. Abstract 1287: The dual IAP antagonist, ASTX660, increases the anti-tumor activity of NSC 125973 in preclinical models of triple-negative breast cancer in vivo. Cancer Res 2016;76(14 Suppl).

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SDS
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