Home Amines 1800046-95-0
1800046-95-0
Catalog No.:AA01LIDF

1800046-95-0 | 6-(6-amino-2-pyrazinyl)-N-[4-[4-(3-oxetanyl)-1-piperazinyl]phenyl]-imidazo[1,2-a]<wbr.<pyrazin-8-amine

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Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$70.00   $49.00
- +
5mg
≥98%
in stock  
$272.00   $190.00
- +
10mg
≥98%
in stock  
$509.00   $356.00
- +
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  • Technical Information
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Technical Information
Catalog Number:
AA01LIDF
Chemical Name:
6-(6-amino-2-pyrazinyl)-N-[4-[4-(3-oxetanyl)-1-piperazinyl]phenyl]-imidazo[1,2-a]<wbr.<pyrazin-8-amine
CAS Number:
1800046-95-0
Molecular Formula:
C23H25N9O
Molecular Weight:
443.5043
SMILES:
Nc1cncc(n1)c1cn2ccnc2c(n1)Nc1ccc(cc1)N1CCN(CC1)C1COC1
Properties

Literature

Title: Di Paolo J, et al. FRI0049 Preclinical Characterization of GS-9876, A Novel, Oral SYK Inhibitor That Shows Efficacy in Multiple Established Rat Models of Collagen-Induced Arthritis.Annals of the Rheumatic Diseases 2016;75:443-444.

Title: Clarke AS, et al. Effects of GS-9876, a novel spleen tyrosine kinase inhibitor, on platelet function and systemic hemostasis. Thromb Res. 2018 Oct;170:109-118.

Title: Kivitz AJ, et al. GS-9876, a Novel, Highly Selective, SYK Inhibitor in Patients with Active Rheumatoid Arthritis: Safety, Tolerability and Efficacy Results of a Phase 2 Study [abstract Arthritis Rheumatol.2018; 70 (suppl 10).

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Tags:1800046-95-0 Molecular Formula|1800046-95-0 MDL|1800046-95-0 SMILES|1800046-95-0 6-(6-amino-2-pyrazinyl)-N-[4-[4-(3-oxetanyl)-1-piperazinyl]phenyl]-imidazo[1,2-a]<wbr.<pyrazin-8-amine