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Home Other Building Blocks 182821-27-8
182821-27-8,MFCD00951548
Catalog No.:AA00ATBN

182821-27-8 | SLV 306

Pack Size
Purity
Availability
Price(USD)
Quantity
  
2mg
99%
in stock  
$303.00   $212.00
- +
5mg
99%
in stock  
$500.00   $350.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00ATBN
Chemical Name:
SLV 306
CAS Number:
182821-27-8
Molecular Formula:
C31H38N2O6
Molecular Weight:
534.6432
MDL Number:
MFCD00951548
SMILES:
CCOC(=O)C(CCC1=CC=CC=C1)CC2(CCCC2)C(=O)NC3CCC4=CC=CC=C4N(C3=O)CC(=O)O
Properties
Computed Properties
 
Complexity:
863  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
39  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
12  
XLogP3:
4.9  

Literature

Title: The dual endothelin converting enzyme/neutral endopeptidase inhibitor SLV-306 (daglutril), inhibits systemic conversion of big endothelin-1 in humans.

Journal: Life sciences 20121015

Title: Inhibition of both neutral endopeptidase and endothelin-converting enzyme by SLV306 reduces proteinuria and urinary albumin excretion in diabetic rats.

Journal: Journal of cardiovascular pharmacology 20041101

Title: [Physiological and pathophysiological roles of the endothelin converting enzymes].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20040901

Title: Effect of single doses of SLV306, an inhibitor of both neutral endopeptidase and endothelin-converting enzyme, on pulmonary pressures in congestive heart failure.

Journal: The American journal of cardiology 20040715

Title: SLV-306. Solvay.

Journal: Current opinion in investigational drugs (London, England : 2000) 20030301

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