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187870-95-7,MFCD30533664
Catalog No.:AA00AE31

187870-95-7 | Rimeporide Hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$216.00   $152.00
- +
2mg
95%
1 week  
$284.00   $199.00
- +
5mg
95%
1 week  
$432.00   $303.00
- +
10mg
95%
1 week  
$562.00   $393.00
- +
25mg
95%
1 week  
$891.00   $624.00
- +
50mg
95%
1 week  
$1,186.00   $830.00
- +
100mg
95%
1 week  
$1,646.00   $1,152.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00AE31
Chemical Name:
Rimeporide Hydrochloride
CAS Number:
187870-95-7
Molecular Formula:
C11H16ClN3O5S2
Molecular Weight:
369.8448
MDL Number:
MFCD30533664
SMILES:
NC(=N)NC(=O)c1cc(c(cc1C)S(=O)(=O)C)S(=O)(=O)C.Cl
Properties
Computed Properties
 
Complexity:
638  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  

Literature

Title: Expression of mitochondrial fusion-fission proteins during post-infarction remodeling: the effect of NHE-1 inhibition.

Journal: Basic research in cardiology 20110101

Title: Sodium-hydrogen exchange inhibition attenuates glycoside-induced hypertrophy in rat ventricular myocytes.

Journal: Cardiovascular research 20100101

Title: Antihypertrophic effect of Na+/H+ exchanger isoform 1 inhibition is mediated by reduced mitogen-activated protein kinase activation secondary to improved mitochondrial integrity and decreased generation of mitochondrial-derived reactive oxygen species.

Journal: The Journal of pharmacology and experimental therapeutics 20060601

Title: F.Porte-Thomé, et al. Development of Rimeporide, a sodium-hydrogen exchanger (NHE-1) inhibitor, for patients with Duchenne muscular dystrophy. Neuromuscular Disorders. October 2015 Oct 25:259-260.

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SDS
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