Home Other Building Blocks 1998705-64-8
1998705-64-8,MFCD34179066
Catalog No.:AA01V7DQ

1998705-64-8 | AT-511

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1mg
≥98%
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$63.00   $44.00
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25mg
95%
in stock  
$236.00   $165.00
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Technical Information
Catalog Number:
AA01V7DQ
Chemical Name:
AT-511
CAS Number:
1998705-64-8
Molecular Formula:
C24H33FN7O7P
Molecular Weight:
581.5337
MDL Number:
MFCD34179066
SMILES:
CNc1nc(N)nc2c1ncn2[C@@H]1O[C@@H]([C@H]([C@@]1(C)F)O)CO[P@@](=O)(N[C@H](C(=O)OC(C)C)C)Oc1ccccc1
Properties

Literature

Title: Steven S Good, et al. Preclinical evaluation of AT-527, a novel guanosine nucleotide prodrug with potent, pan-genotypic activity against hepatitis C virus. PLoS One. 2020 Jan 8;15(1):e0227104.

Title: Steven S Good, et al. AT-527, a double prodrug of a guanosine nucleotide analog, is a potent inhibitor of SARS-CoV-2 in vitro and a promising oral antiviral for treatment of COVID-19. Antimicrob Agents Chemother. 2021 Feb 8;AAC.02479-20.

Title: Elina Berliba, et al. Safety, pharmacokinetics and antiviral activity of AT-527, a novel purine nucleotide prodrug, in HCV-infected subjects with and without cirrhosis. Antimicrob Agents Chemother. 2019 Sep 30;63(12):e01201-19.

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Tags:1998705-64-8 Molecular Formula|1998705-64-8 MDL|1998705-64-8 SMILES|1998705-64-8 AT-511