Home Other Building Blocks 2070015-10-8
2070015-10-8,MFCD05662337
Catalog No.:AA01EOF0

2070015-10-8 | ML204 hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$15.00   $11.00
- +
5mg
98+%
in stock  
$35.00   $25.00
- +
10mg
98+%
in stock  
$52.00   $36.00
- +
50mg
98+%
in stock  
$138.00   $96.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EOF0
Chemical Name:
ML204 hydrochloride
CAS Number:
2070015-10-8
Molecular Formula:
C15H19ClN2
Molecular Weight:
262.7778
MDL Number:
MFCD05662337
SMILES:
Cc1cc(nc2c1cccc2)N1CCCCC1.Cl
Properties
Computed Properties
 
Complexity:
247  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  

Literature

Title: Miller M, et al. Identification of ML204, a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels. J Biol Chem. 2011 Sep 23;286(38):33436-46.

Title: Miller MR, et al. Novel Chemical Inhibitor of TRPC4 Channels. Probe Reports from the NIH Molecular Libraries Program.

Title: Thomas Schaldecker, et al. Inhibition of the TRPC5 ion channel protects the kidney filter. J Clin Invest. 2013 Dec 2; 123(12): 5298–5309.

Title: Domingos M S Pereira, et al. Transient Receptor Potential Canonical Channels 4 and 5 Mediate Escherichia coli-Derived Thioredoxin Effects in Lipopolysaccharide-Injected Mice. Oxid Med Cell Longev. 2018 Jun 10;2018:4904696.

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SDS
Tags:2070015-10-8 Molecular Formula|2070015-10-8 MDL|2070015-10-8 SMILES|2070015-10-8 ML204 hydrochloride