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2097132-94-8,MFCD31692384
Catalog No.:AA01FN66

2097132-94-8 | Blu-667

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
99%
in stock  
$30.00   $21.00
- +
5mg
99%
in stock  
$75.00   $53.00
- +
25mg
99%
in stock  
$187.00   $131.00
- +
100mg
95%
in stock  
$724.00   $507.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01FN66
Chemical Name:
Blu-667
CAS Number:
2097132-94-8
Molecular Formula:
C27H32FN9O2
Molecular Weight:
533.6005
MDL Number:
MFCD31692384
SMILES:
CO[C@@]1(CC[C@H](CC1)c1nc(C)cc(n1)Nc1n[nH]c(c1)C)C(=O)N[C@H](c1ccc(nc1)n1ncc(c1)F)C
Properties
Computed Properties
 
Complexity:
816  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
39  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
3.1  

Downstream Synthesis Route

[1]CurrentPatentAssignee:BLUEPRINTMEDICINESCORP-WO2017/79140,2017,A1

139042-59-4   
trans-N-((S)-1-(6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethyl)-1-methoxy-4-(4-methyl-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)cyclohexanecarboxamide 
 
(1S,4R)-N-((S)-1-(6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethyl)-1-methoxy-4-(4-methyl-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)cyclohexanecarboxamide 

[1]Patent:WO2017/79140,2017,A1

[1]CurrentPatentAssignee:BLUEPRINTMEDICINESCORP-WO2017/79140,2017,A1

[1]CurrentPatentAssignee:BLUEPRINTMEDICINESCORP-WO2017/79140,2017,A1Locationinpatent:Page/Pagecolumn52;53

[1]CurrentPatentAssignee:WEIWEI-CN111362923,2020,ALocationinpatent:Paragraph0089-000099

Literature

Title: Precision Targeted Therapy with BLU-667 for RET-Driven Cancers.

Journal: Cancer discovery 20180701

Title: Subbiah V, et al. Precision Targeted Therapy With BLU-667 for RET-Driven Cancers. American Association for Cancer Research. 10.1158/2159-8290.CD-18-0338.

Quotation Request
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SDS
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Tags:2097132-94-8 Molecular Formula|2097132-94-8 MDL|2097132-94-8 SMILES|2097132-94-8 Blu-667
Catalog No.: AA01FN66
2097132-94-8,MFCD31692384
2097132-94-8 | Blu-667
Pack Size： 1mg
Purity： 99%
in stock
$30.00 $21.00
Pack Size： 5mg
Purity： 99%
in stock
$75.00 $53.00
Pack Size： 25mg
Purity： 99%
in stock
$187.00 $131.00
Pack Size： 100mg
Purity： 95%
in stock
$724.00 $507.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA01FN66
Chemical Name: Blu-667
CAS Number: 2097132-94-8
Molecular Formula: C27H32FN9O2
Molecular Weight: 533.6005
MDL Number: MFCD31692384
SMILES: CO[C@@]1(CC[C@H](CC1)c1nc(C)cc(n1)Nc1n[nH]c(c1)C)C(=O)N[C@H](c1ccc(nc1)n1ncc(c1)F)C
Properties
Complexity: 816  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 39  
Hydrogen Bond Acceptor Count: 9  
Hydrogen Bond Donor Count: 3  
Isotope Atom Count: 0  
Rotatable Bond Count: 8  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 3.1  
Downstream Synthesis Route
1980023-94-6    2097132-93-7    2097132-94-8 

[1]CurrentPatentAssignee:BLUEPRINTMEDICINESCORP-WO2017/79140,2017,A1

139042-59-4   
trans-N-((S)-1-(6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethyl)-1-methoxy-4-(4-methyl-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)cyclohexanecarboxamide 
 
(1S,4R)-N-((S)-1-(6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethyl)-1-methoxy-4-(4-methyl-6-((5-methyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)cyclohexanecarboxamide 

[1]Patent:WO2017/79140,2017,A1

1980023-95-7    2097132-93-7    2097132-94-8 

[1]CurrentPatentAssignee:BLUEPRINTMEDICINESCORP-WO2017/79140,2017,A1

1980023-96-8    2459966-45-9    2097132-93-7    2097132-94-8 

[1]CurrentPatentAssignee:BLUEPRINTMEDICINESCORP-WO2017/79140,2017,A1Locationinpatent:Page/Pagecolumn52;53

1980023-96-8    2459966-45-9    2097132-94-8 

[1]CurrentPatentAssignee:WEIWEI-CN111362923,2020,ALocationinpatent:Paragraph0089-000099

Literature fold

Title: Precision Targeted Therapy with BLU-667 for RET-Driven Cancers.

Journal: Cancer discovery20180701

Title: Subbiah V, et al. Precision Targeted Therapy With BLU-667 for RET-Driven Cancers. American Association for Cancer Research. 10.1158/2159-8290.CD-18-0338.

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