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Title: The binding of synthetic triiodo l-thyronine analogs to human transthyretin: molecular basis of cooperative and non-cooperative ligand recognition.
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Title: TRbeta is the critical thyroid hormone receptor isoform in T3-induced proliferation of hepatocytes and pancreatic acinar cells.
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Title: The T3 receptor beta1 isoform regulates UCP1 and D2 deiodinase in rat brown adipocytes.
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Title: Human platelet aggregation and degranulation is induced in vitro by L-thyroxine, but not by 3,5,3'-triiodo-L-thyronine or diiodothyropropionic acid (DITPA).
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Title: The TRbeta-selective agonist, GC-1, stimulates mitochondrial oxidative processes to a lesser extent than triiodothyronine.
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Title: The thyroid hormone receptor (TR) beta-selective agonist GC-1 inhibits proliferation but induces differentiation and TR beta mRNA expression in mouse and rat osteoblast-like cells.
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Title: T3 and the thyroid hormone beta-receptor agonist GC-1 differentially affect metabolic capacity and oxidative damage in rat tissues.
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Title: Thyroid hormone receptor subtype specificity for hormone-dependent neurogenesis in Xenopus laevis.
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Title: Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist.
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Title: Synthesis and biological evaluation of a series of liver-selective phosphonic acid thyroid hormone receptor agonists and their prodrugs.
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Title: Thyroid hormone (T3) and TRbeta agonist GC-1 inhibit/reverse nonalcoholic fatty liver in rats.
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Title: Thyroid hormone analogues: useful biological probes and potential therapeutic agents.
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Title: Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
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Title: Influence of thyroid hormone and thyroid hormone receptors in the generation of cerebellar gamma-aminobutyric acid-ergic interneurons from precursor cells.
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Title: Thyroid hormone receptor beta-specific agonist GC-1 increases energy expenditure and prevents fat-mass accumulation in rats.
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Title: A phosphorimager-based filter binding thyroid hormone receptor competition assay for chemical screening.
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Title: The thyroid hormone receptor-beta agonist GC-1 induces cell proliferation in rat liver and pancreas.
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Title: Analysis of thyroid hormone receptor betaA mRNA expression in Xenopus laevis tadpoles as a means to detect agonism and antagonism of thyroid hormone action.
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Title: Different configurations of specific thyroid hormone response elements mediate opposite effects of thyroid hormone and GC-1 on gene expression.
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Title: The proangiogenic action of thyroid hormone analogue GC-1 is initiated at an integrin.
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Title: Mutant-selective thyromimetics for the chemical rescue of thyroid hormone receptor mutants associated with resistance to thyroid hormone.
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Title: The thyroid hormone receptor beta-specific agonist GC-1 selectively affects the bone development of hypothyroid rats.
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Title: Thyroid hormone-dependent seasonality in American tree sparrows (Spizella arborea): effects of GC-1, a thyroid receptor beta-selective agonist, and of iopanoic acid, a deiodinase inhibitor.
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Title: Induction of larval tissue resorption in Xenopus laevis tadpoles by the thyroid hormone receptor agonist GC-1.
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Title: Effects of the thyroid hormone receptor agonist GC-1 on metabolic rate and cholesterol in rats and primates: selective actions relative to 3,5,3'-triiodo-L-thyronine.
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Title: Selective activation of thyroid hormone signaling pathways by GC-1: a new approach to controlling cholesterol and body weight.
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Title: Differential effects of triiodothyronine and the thyroid hormone receptor beta-specific agonist GC-1 on thyroid hormone target genes in the b ain.
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Title: Structural determinants of selective thyromimetics.
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Title: Rational design and synthesis of a novel thyroid hormone antagonist that blocks coactivator recruitment.
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Title: Synthesis and biological activity of novel thyroid hormone analogues: 5'-aryl substituted GC-1 derivatives.
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Title: A designed antagonist of the thyroid hormone receptor.
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Title: Regulation of thyroid hormone receptor isoforms in physiological and pathological cardiac hypertrophy.
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Title: Thyroid hormone--sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform--specific.
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Title: Hormone selectivity in thyroid hormone receptors.
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Title: A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor.
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Title: Binding of 3,5,3'-triiodothyronine (T3) and its analogs to the in vitro translational products of c-erbA protooncogenes: differences in the affinity of the alpha- and beta-forms for the acetic acid analog and failure of the human testis and kidney alpha-2 products to bind T3.
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Title: Opiate-dependent modulation of adenylate cyclase.
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