Home Amines 212391-58-7
212391-58-7,MFCD28384718
Catalog No.:AA00BF51

212391-58-7 | Pyrido[2,3-d]pyrimidin-7(8H)-one,2-[[4-(2-aminoethoxy)phenyl]amino]-6-(2,6-dichlorophenyl)-8-methyl-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$102.00   $72.00
- +
5mg
95%
1 week  
$164.00   $115.00
- +
10mg
95%
1 week  
$226.00   $158.00
- +
25mg
95%
1 week  
$351.00   $246.00
- +
50mg
99%
1 week  
$355.00   $249.00
- +
100mg
99%
1 week  
$603.00   $423.00
- +
250mg
99%
1 week  
$1,021.00   $715.00
- +
1g
99%
1 week  
$2,771.00   $1,940.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BF51
Chemical Name:
Pyrido[2,3-d]pyrimidin-7(8H)-one,2-[[4-(2-aminoethoxy)phenyl]amino]-6-(2,6-dichlorophenyl)-8-methyl-
CAS Number:
212391-58-7
Molecular Formula:
C22H19Cl2N5O2
Molecular Weight:
456.3246
MDL Number:
MFCD28384718
SMILES:
NCCOc1ccc(cc1)Nc1ncc2c(n1)n(C)c(=O)c(c2)c1c(Cl)cccc1Cl
Properties
Computed Properties
 
Complexity:
648  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
XLogP3:
3.9  

Literature

Title: 2-Substituted aminopyrido[2,3-d]pyrimidin-7(8H)-ones. structure-activity relationships against selected tyrosine kinases and in vitro and in vivo anticancer activity.

Journal: Journal of medicinal chemistry 19980813

Title: Wissing J, et al. Chemical Proteomic Analysis Reveals Alternative Modes of Action for Pyrido,3-dpyrimidine Kinase Inhibitors. Mol Cell Proteomics. 2004 Dec;3(12):1181-93.

Title: Blencke S, et al. Characterization of a conserved structural determinant controlling protein kinase sensitivity to selective inhibitors. Chem Biol. 2004 May;11(5):691-701.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:212391-58-7 Molecular Formula|212391-58-7 MDL|212391-58-7 SMILES|212391-58-7 Pyrido[2,3-d]pyrimidin-7(8H)-one,2-[[4-(2-aminoethoxy)phenyl]amino]-6-(2,6-dichlorophenyl)-8-methyl-