Name: Name:2-(3-Hydroxy-4-methoxyphenyl)-5,6,7-trimethoxy-4H-chromen-4-one
Brand: AABLOCKS
SKU: AA006ZC9
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA006ZC9

Chemical Name: 2-(3-Hydroxy-4-methoxyphenyl)-5,6,7-trimethoxy-4H-chromen-4-one

CAS Number: 21764-09-0

Molecular Formula: C19H18O7

Molecular Weight: 358.3420

MDL Number: MFCD00016928

SMILES: COc1cc2oc(cc(=O)c2c(c1OC)OC)c1ccc(c(c1)O)OC

Properties

Complexity: 534

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 26

Hydrogen Bond Acceptor Count: 7

Hydrogen Bond Donor Count: 1

Isotope Atom Count: 0

Rotatable Bond Count: 5

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 2.7

Literature fold

Title: Benzo[a]pyrene sensitizes MCF7 breast cancer cells to induction of G1 arrest by the natural flavonoid eupatorin-5-methyl ether, via activation of cell signaling proteins and CYP1-mediated metabolism.

Journal: Toxicology letters20141015

Title: A simple isocratic HPLC method for the simultaneous determination of sinensetin, eupatorin, and 3'-hydroxy-5,6,7,4'-tetramethoxyflavone in Orthosiphon stamineus extracts.

Journal: Journal of acupuncture and meridian studies20120801

Title: Flavonoids eupatorin and sinensetin present in Orthosiphon stamineus leaves inhibit inflammatory gene expression and STAT1 activation.

Journal: Planta medica20120501

Title: Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids.

Journal: Bioorganic & medicinal chemistry20110501

Title: HPLC and anti-inflammatory studies of the flavonoid rich chloroform extract fraction of Orthosiphon stamineus leaves.

Journal: Molecules (Basel, Switzerland)20100621

Title: Polymethoxylated flavones induce Ca(2+)-mediated apoptosis in breast cancer cells.

Journal: Life sciences20061223

Title: Effects of flavonoids on cell proliferation and caspase activation in a human colonic cell line HT29: an SAR study.

Journal: Journal of medicinal chemistry20050421

Title: Determination of flavonoids from Orthosiphon stamineus in plasma using a simple HPLC method with ultraviolet detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20050225

Title: The total synthesis of an aurone isolated from Uvaria hamiltonii: aurones and flavones as anticancer agents.

Journal: Bioorganic & medicinal chemistry letters20031103

21764-09-0 | 2-(3-Hydroxy-4-methoxyphenyl)-5,6,7-trimethoxy-4H-chromen-4-one