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25137-00-2,MFCD01630787
Catalog No.:AA00I4PV

25137-00-2 | (R)-Piperidine-3-carboxylic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
98%
in stock  
$7.00   $5.00
- +
1g
98%
in stock  
$12.00   $8.00
- +
100g
≥ 98% (assay by titration)
in stock  
$922.00   $645.00
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500g
98%
in stock  
$3,803.00   $2,662.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I4PV
Chemical Name:
(R)-Piperidine-3-carboxylic acid
CAS Number:
25137-00-2
Molecular Formula:
C6H11NO2
Molecular Weight:
129.1570
MDL Number:
MFCD01630787
SMILES:
OC(=O)[C@@H]1CCCNC1
Properties
Computed Properties
 
Complexity:
114  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
-2.9  

Downstream Synthesis Route
3398-40-1   
5-5-3-3-(3-bromopropoxy)-2-methylphenyl-2-methylphenylmethoxy-4-chloro-2-formylphenoxymethylpyridine-3-carbonitrile 
  498-95-3   
(3R)-1-(3-(3'-((4-(((S)-2-carboxy-1-hydroxypropan-2-ylamino)methyl)-2-chloro-5-((5-cyanopyridin-3-yl)methoxy)phenoxy)methyl)-2,2'-dimethylbiphenyl-3-yloxy)propyl)piperidine-3-carboxylicacid 

[1]Patent:US2017/107202,2017,A1.Locationinpatent:Paragraph1523;1524

Literature

Title: Homology modelling of the GABA transporter and analysis of tiagabine binding.

Journal: ChemMedChem 20100705

Title: Azetidine derivatives as novel gamma-aminobutyric acid uptake inhibitors: synthesis, biological evaluation, and structure-activity relationship.

Journal: European journal of medicinal chemistry 20100601

Title: Synthesis and biological evaluation of aminomethylphenol derivatives as inhibitors of the murine GABA transporters mGAT1-mGAT4.

Journal: European journal of medicinal chemistry 20081101

Title: Synthesis and biological evaluation of (R)-N-(diarylmethylthio/sulfinyl)ethyl/propyl-piperidine-3-carboxylic acid hydrochlorides as novel GABA uptake inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20070701

Title: Design, synthesis, and biological evaluation of the N-diarylalkenyl-piperidinecarboxylic acid derivatives as GABA uptake inhibitors (I).

Journal: Bioorganic & medicinal chemistry letters 20060101

Title: Novel secoergoline derivatives inhibit both GABA and glutamate uptake in rat brain homogenates: synthesis, in vitro pharmacology, and modeling.

Journal: Journal of medicinal chemistry 20041104

Title: Assay for nipecotic acid in small blood samples by gas chromatography-mass spectroscopy.

Journal: Journal of pharmaceutical and biomedical analysis 20040310

Title: Delta-Aminolevulinic acid transport in murine mammary adenocarcinoma cells is mediated by beta transporters.

Journal: British journal of cancer 20020812

Title: Protein prosthesis: a semisynthetic enzyme with a beta-peptide reverse turn.

Journal: Journal of the American Chemical Society 20020724

Title: Pharmacological evidence for GABAergic regulation of specific behaviors in Drosophila melanogaster.

Journal: Journal of neurobiology 20020215

Title: Action of 4-amino-2-fluorobutanoic acid and other structural analogues on gamma-aminobutyric acid transport by channel catfish brain.

Journal: Journal of basic and clinical physiology and pharmacology 20020101

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SDS
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Tags:25137-00-2 Molecular Formula|25137-00-2 MDL|25137-00-2 SMILES|25137-00-2 (R)-Piperidine-3-carboxylic acid