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25953-17-7,MFCD00083410
Catalog No.:AA00BF3H

25953-17-7 | Minaprine dihydrochloride

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100mg
95%
1 week  
$104.00   $73.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BF3H
Chemical Name:
Minaprine dihydrochloride
CAS Number:
25953-17-7
Molecular Formula:
C17H24Cl2N4O
Molecular Weight:
371.3047
MDL Number:
MFCD00083410
SMILES:
Cc1cc(nnc1NCCN1CCOCC1)c1ccccc1.Cl.Cl
Properties
Computed Properties
 
Complexity:
316  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  

Literature

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Molecular properties and CYP2D6 substrates: central nervous system therapeutics case study and pattern analysis of a substrate database.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20091101

Title: Pharmacological evaluation of minaprine dihydrochloride, a new psychotropic drug.

Journal: Arzneimittel-Forschung 19820101

Title: Kan JP, et al. Effect of the antidepressant minaprine on both forms of monoamine oxidase in the rat. Biochem Pharmacol. 1986 Mar 15;35(6):973-8.

Title: Contreras JM, et al. Aminopyridazines as acetylcholinesterase inhibitors. J Med Chem. 1999 Feb 25;42(4):730-41.

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SDS
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