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25999-20-6,MFCD00078065
Catalog No.:AA00BD97

25999-20-6 | LASALOCID A SODIUM SALT

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5mg
97%
1 week  
$146.00   $102.00
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10mg
97%
1 week  
$209.00   $147.00
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25mg
97%
1 week  
$336.00   $235.00
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50mg
97%
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$479.00   $335.00
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100mg
97%
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$654.00   $458.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BD97
Chemical Name:
LASALOCID A SODIUM SALT
CAS Number:
25999-20-6
Molecular Formula:
C34H53NaO8
Molecular Weight:
612.7696
MDL Number:
MFCD00078065
SMILES:
CC[C@@H](C(=O)[C@H]([C@H]([C@@H](CCc1ccc(c(c1C(=O)[O-])O)C)C)O)C)[C@H]1O[C@](C[C@@H]1C)(CC)[C@H]1CC[C@]([C@@H](O1)C)(O)CC.[Na+]
Properties
Properties
 
Form:
Solid  
MP:
180℃ (dec.)(lit.)  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
917  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
10  
Heavy Atom Count:
43  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
13  

Literature

Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.

Journal: Bioorganic & medicinal chemistry 20121115

Title: Structural characterization of polyketides using high mass accuracy tandem mass spectrometry.

Journal: Analytical chemistry 20121016

Title: Assessment of dietary supplementation with probiotics on performance, intestinal morphology and microflora of chickens infected with Eimeria tenella.

Journal: Veterinary parasitology 20120813

Title: Sequential enzymatic epoxidation involved in polyether lasalocid biosynthesis.

Journal: Journal of the American Chemical Society 20120502

Title: Biochemistry: favouring the unfavoured.

Journal: Nature 20120314

Title: Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis.

Journal: Nature 20120304

Title: Determination of lasalocid residues in the tissues of broiler chickens by liquid chromatography-tandem mass spectrometry.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101

Title: Acute and long-term cardiomyopathy and delayed neurotoxicity after accidental lasalocid poisoning in horses.

Journal: Journal of veterinary internal medicine 20120101

Title: Tissue Doppler imaging and 2-dimensional speckle tracking of left ventricular function in horses exposed to lasalocid.

Journal: Journal of veterinary internal medicine 20120101

Title: Transfer of the coccidiostats monensin and lasalocid from feed at cross-contamination levels to whole egg, egg white and egg yolk.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101

Title: Determination of narasin and monensin in bovine, swine, and chicken tissues by liquid chromatography with tandem mass spectrometry: first action 2011.24.

Journal: Journal of AOAC International 20120101

Title: Rapid method for the simultaneous determination of six ionophores in feed by liquid chromatography/mass spectrometry.

Journal: Journal of AOAC International 20120101

Title: Insights into lasalocid A ring formation by chemical chain termination in vivo.

Journal: Angewandte Chemie (International ed. in English) 20111209

Title: Acute lasalocid poisoning in calves associated with off-label use.

Journal: Journal of veterinary pharmacology and therapeutics 20110401

Title: Pediococcus acidilactici isolated from the rumen of lambs with rumen acidosis, 16S rRNA identification and sensibility to monensin and lasalocid.

Journal: Research in veterinary science 20110201

Title: Identification of clinically used drugs that activate pregnane X receptors.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110101

Title: Lasalocid awareness and sampling in Scotland.

Journal: International journal of environmental health research 20100601

Title: Intriguing substrate tolerance of epoxide hydrolase Lsd19 involved in biosynthesis of the ionophore antibiotic lasalocid A.

Journal: Organic letters 20100521

Title: Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.

Journal: Bioscience, biotechnology, and biochemistry 20090101

Title: Analysis of specific mutants in the lasalocid gene cluster: evidence for enzymatic catalysis of a disfavoured polyether ring closure.

Journal: Chembiochem : a European journal of chemical biology 20081215

Title: Efficacy of lasalocid against coccidiosis in Chinese ring-necked pheasants.

Journal: Avian diseases 20081201

Title: Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.

Journal: Journal of the American Chemical Society 20080917

Title: Doubly compensated multiplicity-edited HSQC experiments utilizing broadband inversion pulses.

Journal: Magnetic resonance in chemistry : MRC 20080701

Title: Determination of lasalocid sodium in animal feeds and premixes by reversed-phase liquid chromatography: collaborative study.

Journal: Journal of AOAC International 20080101

Title: Effects of lasalocid or monensin supplementation on digestion, ruminal fermentation, blood metabolites, and milk production of lactating dairy cows.

Journal: Journal of dairy science 20071201

Title: Sorption and degradation in soils of veterinary ionophore antibiotics: monensin and lasalocid.

Journal: Environmental toxicology and chemistry 20070801

Title: Mucosal mast cell proteases are involved in colonic permeability alterations and subsequent bacterial translocation in endotoxemic rats.

Journal: Shock (Augusta, Ga.) 20070701

Title: Changes in net portal nutrient flux in response to weaning transition and ionophore supplementation in dairy calves.

Journal: Journal of dairy science 20070301

Title: Effects of weaning and ionophore supplementation on selected blood metabolites and growth in dairy calves.

Journal: Journal of dairy science 20060901

Title: Efficacy of ionophores in cattle diets for mitigation of enteric methane.

Journal: Journal of animal science 20060701

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Simultaneous determination of four coccidiostats in eggs and broiler meat: validation of an LC-MS/MS method.

Journal: Food additives and contaminants 20060501

Title: Incidence of residues of nine anticoccidials in eggs.

Journal: Food additives and contaminants 20051101

Title: The solution structure of a lasalocid A metal complex in lipophilic solvents.

Journal: Bioorganic & medicinal chemistry 20050901

Title: [Cryptosporidiosis in newborn calves in Ankara region: clinical, haematological findings and treatment with Lasalocid-NA].

Journal: DTW. Deutsche tierarztliche Wochenschrift 20050601

Title: A band-selective composite gradient: application to DQF-COSY.

Journal: Journal of magnetic resonance (San Diego, Calif. : 1997) 20050501

Title: A comparison of data analysis methods for determining gas phase stabilities by CID: alkali metal complexes of polyether ionophore antibiotics.

Journal: Journal of the American Society for Mass Spectrometry 20050501

Title: Periodicity in collision-induced and remote-bond activation of alkali metal ions attached to polyether ionophores.

Journal: The Analyst 20050401

Title: Determination of the ionophoric coccidiostats narasin, monensin, lasalocid and salinomycin in eggs by liquid chromatography/tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20050101

Title: Extending the limits of the selective 1D NOESY experiment with an improved selective TOCSY edited preparation function.

Journal: Journal of magnetic resonance (San Diego, Calif. : 1997) 20041201

Title: Ionophore taste preferences of dairy heifers.

Journal: Journal of animal science 20041101

Title: Production and health of pasture-fed dairy cattle following oral treatment with the ionophore lasalocid.

Journal: Journal of dairy science 20040901

Title: Accidental poisoning of 17 dogs with lasalocid.

Journal: The Veterinary record 20040807

Title: [Development of monoclonal-based enzyme-linked immunosorbent assay and immunochromatographic assay for lasalocid and semduramicin].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20040601

Title: Isolation and selection of ionophore-tolerant Eimeria precocious lines: E. tenella, E. maxima and E. acervulina.

Journal: Veterinary parasitology 20040206

Title: An alternative to antibiotic-based drugs in feed for enhancing performance of broilers grown on Eimeria spp.-infected litter.

Journal: Poultry science 20040101

Title: Rapid forensic selected reaction monitoring liquid chromatography/mass spectrometry determination of ionophore antibiotics found at toxic levels in animal feeds.

Journal: Journal of AOAC International 20040101

Title: Inhibition of resistance plasmid transfer in Escherichia coli by ionophores, chlortetracycline, bacitracin, and ionophore/antimicrobial combinations.

Journal: Avian diseases 20040101

Title: Effect of lasalocid on growth, blood gases, and nutrient utilization in dairy goats fed a high forage, low protein diet.

Journal: Journal of dairy science 20031201

Title: Suspected lasalocid poisoning in three dogs.

Journal: Veterinary and human toxicology 20031001

Title: Guanidinium receptors as enantioselective amino acid membrane carriers.

Journal: Journal of the American Chemical Society 20030709

Title: Effects of lasalocid on circulating concentrations of leptin and insulin-like growth factor-I and reproductive performance of postpartum Brahman cows.

Journal: Journal of animal science 20030601

Title: Effect of dietary supplementation with oregano essential oil on performance of broilers after experimental infection with Eimeria tenella.

Journal: Archiv fur Tierernahrung 20030401

Title: Effects of the antibiotic ionophores monensin, lasalocid, laidlomycin propionate and bambermycin on Salmonella and E. coli O157:H7 in vitro.

Journal: Journal of applied microbiology 20030101

Title: Multinuclear NMR and FTIR studies of new polyoxaalkyl esters of lasalocid and their complexes with lithium and sodium cations.

Journal: Biopolymers 20021015

Title: [Effects of veterinary drugs on beta-hexosaminidase release from rat basophilic leukemia cells (RBL-2H3)].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20021001

Title: Fragmentation studies on lasalocid acid by accurate mass electrospray mass spectrometry.

Journal: The Analyst 20020901

Title: Use of an adsorbed chiral selector in capillary LC-MS.

Journal: Chirality 20020801

Title: Lasalocid toxicosis is inadequately quantified for horses.

Journal: Veterinary and human toxicology 20020801

Title: Effect of lonophore supplementation on selected serum constituents of sheep consuming locoweed.

Journal: Veterinary and human toxicology 20020601

Title: Improved clean-up for the determination of lasalocid in 'difficult' food matrices.

Journal: Food additives and contaminants 20020101

Title: Effects of dietary rice bran, lasalocid, and sex of calf on postpartum reproduction in Brahman cows.

Journal: Journal of animal science 20011201

Title: Secretion of the trefoil factor TFF3 from the isolated vascularly perfused rat colon.

Journal: Regulatory peptides 20010915

Title: Nutritionally directed compensatory growth enhances heifer development and lactation potential.

Journal: Journal of dairy science 20010701

Title: 7Li-NMR and FTIR studies of lithium, potassium, rubidium, and cesium complexes with ionophore lasalocid in solution.

Journal: Biopolymers 20010101

Title: LC/MS confirmation of ionophores in animal feeds.

Journal: Journal of AOAC International 20010101

Title: Interaction of fluoroquinolones and certain ionophores in broilers: effect on blood levels and hepatic cytochrome p450 monooxygenase activity.

Journal: Drug metabolism and drug interactions 20010101

Title: Anticryptosporidial activity of ranalexin, lasalocid and azithromycin alone and in combination in cell lines.

Journal: The Journal of antimicrobial chemotherapy 20000301

Title: In-vitro activities of paromomycin and lasalocid evaluated in combination against Cryptosporidium parvum.

Journal: The Journal of antimicrobial chemotherapy 19980201

Title: Efficacy of lasalocid against murine Pneumocystis carinii pneumonitis.

Journal: Antimicrobial agents and chemotherapy 19970101

Title: Putative anticryptosporidial agents tested with an immunodeficient mouse model.

Journal: Antimicrobial agents and chemotherapy 19940401

Title: Anticryptosporidial activity of lasalocid and other ionophorous antibiotics in immunosuppressed rats.

Journal: The Journal of infectious diseases 19931201

Title: Chemotherapeutic effect of azithromycin and lasalocid on Cryptosporidium infection in mice.

Journal: The Journal of protozoology 19910101

Title: Okubo-Kurihara E et al. Modification of plant cell wall structure accompanied by enhancement of saccharification efficiency using a chemical, lasalocid sodium. Sci Rep. 2016 Oct 3;6:34602.

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