Home Other Building Blocks 25999-31-9
25999-31-9,MFCD00242774
Catalog No.:AA00BF3D

25999-31-9 | Lasalocid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%
in stock  
$163.00   $114.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BF3D
Chemical Name:
Lasalocid
CAS Number:
25999-31-9
Molecular Formula:
C34H54O8
Molecular Weight:
590.7878
MDL Number:
MFCD00242774
SMILES:
CC[C@@H](C(=O)[C@H]([C@H]([C@@H](CCc1ccc(c(c1C(=O)O)O)C)C)O)C)[C@H]1O[C@](C[C@@H]1C)(CC)[C@H]1CC[C@]([C@@H](O1)C)(O)CC
Properties
Computed Properties
 
Complexity:
910  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
10  
Heavy Atom Count:
42  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
13  
XLogP3:
6.4  

Literature

Title: Structural characterization of polyketides using high mass accuracy tandem mass spectrometry.

Journal: Analytical chemistry 20121016

Title: Development of a five-plex flow cytometric immunoassay for the simultaneous detection of six coccidiostats in feed and eggs.

Journal: Analytical and bioanalytical chemistry 20120901

Title: Assessment of dietary supplementation with probiotics on performance, intestinal morphology and microflora of chickens infected with Eimeria tenella.

Journal: Veterinary parasitology 20120813

Title: Sequential enzymatic epoxidation involved in polyether lasalocid biosynthesis.

Journal: Journal of the American Chemical Society 20120502

Title: Biochemistry: favouring the unfavoured.

Journal: Nature 20120314

Title: Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis.

Journal: Nature 20120304

Title: Simultaneous determination of five polyether ionophores using liquid chromatography with one-step fluorescent derivatization.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20120101

Title: Determination of lasalocid residues in the tissues of broiler chickens by liquid chromatography-tandem mass spectrometry.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101

Title: Acute and long-term cardiomyopathy and delayed neurotoxicity after accidental lasalocid poisoning in horses.

Journal: Journal of veterinary internal medicine 20120101

Title: 'Human babesiosis': an emerging transfusion dilemma.

Journal: International journal of hepatology 20120101

Title: An overview of the evidence and mechanisms of herb-drug interactions.

Journal: Frontiers in pharmacology 20120101

Title: Tissue Doppler imaging and 2-dimensional speckle tracking of left ventricular function in horses exposed to lasalocid.

Journal: Journal of veterinary internal medicine 20120101

Title: Quantification of ionophores in aged poultry litter using liquid chromatography tandem mass spectrometry.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20120101

Title: Transfer of the coccidiostats monensin and lasalocid from feed at cross-contamination levels to whole egg, egg white and egg yolk.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101

Title: Determination of narasin and monensin in bovine, swine, and chicken tissues by liquid chromatography with tandem mass spectrometry: first action 2011.24.

Journal: Journal of AOAC International 20120101

Title: Rapid method for the simultaneous determination of six ionophores in feed by liquid chromatography/mass spectrometry.

Journal: Journal of AOAC International 20120101

Title: Virtual screening as a strategy for the identification of xenobiotics disrupting corticosteroid action.

Journal: PloS one 20120101

Title: Insights into lasalocid A ring formation by chemical chain termination in vivo.

Journal: Angewandte Chemie (International ed. in English) 20111209

Title: Development and validation of an UPLC-MS/MS method for the determination of ionophoric and synthetic coccidiostats in vegetables.

Journal: Analytical and bioanalytical chemistry 20111201

Title: Rapid quantification of ionophores in feeds by liquid chromatography-tandem mass spectrometry.

Journal: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20110901

Title: Determination of eleven coccidiostats in animal feed by liquid chromatography-tandem mass spectrometry at cross contamination levels.

Journal: Analytica chimica acta 20110826

Title: Development and validation of a multi-residue liquid chromatography-tandem mass spectrometry confirmatory method for eleven coccidiostats in eggs.

Journal: Analytica chimica acta 20110826

Title: Enzymatic epoxide-opening cascades catalyzed by a pair of epoxide hydrolases in the ionophore polyether biosynthesis.

Journal: Organic letters 20110401

Title: Acute lasalocid poisoning in calves associated with off-label use.

Journal: Journal of veterinary pharmacology and therapeutics 20110401

Title: Rapid and reliable identification of ionophore antibiotics in feeds by liquid chromatography-tandem mass spectrometry.

Journal: Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20110301

Title: The efficacy of anticoccidial products against Eimeria spp. in northern bobwhites.

Journal: Avian diseases 20110301

Title: Pediococcus acidilactici isolated from the rumen of lambs with rumen acidosis, 16S rRNA identification and sensibility to monensin and lasalocid.

Journal: Research in veterinary science 20110201

Title: Giant linear plasmids in Streptomyces: a treasure trove of antibiotic biosynthetic clusters.

Journal: The Journal of antibiotics 20110101

Title: A new approach to the analysis of nicarbazin and ionophores in eggs by HPLC/MS/MS.

Journal: Journal of AOAC International 20110101

Title: [Simultaneous determination of polyether antibiotics and macrolide anthelmintics in livestock products by liquid chromatography/tandem mass spectrometry].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20110101

Title: Simultaneous determination of polyether ionophores, macrolides and lincosamides in hen eggs by liquid chromatography-electrospray ionization tandem mass spectrometry using a simple solvent extraction.

Journal: Analytica chimica acta 20101203

Title: Evaluation of potential carryover effects associated with limit feeding of gravid Holstein heifers.

Journal: Journal of dairy science 20101101

Title: Selection of single chain variable fragment (scFv) antibodies from a hyperimmunized phage display library for the detection of the antibiotic monensin.

Journal: Journal of immunological methods 20100831

Title: Lasalocid awareness and sampling in Scotland.

Journal: International journal of environmental health research 20100601

Title: Intriguing substrate tolerance of epoxide hydrolase Lsd19 involved in biosynthesis of the ionophore antibiotic lasalocid A.

Journal: Organic letters 20100521

Title: An unusual thioesterase promotes isochromanone ring formation in ajudazol biosynthesis.

Journal: Chembiochem : a European journal of chemical biology 20100517

Title: Direct aqueous supercritical fluid extraction coupled on-line with liquid chromatography-tandem mass spectrometry for the analysis of polyether ionophore antibiotics in water.

Journal: Journal of chromatography. A 20100514

Title: The effect of commonly used anticoccidials and antibiotics in a subclinical necrotic enteritis model.

Journal: Avian pathology : journal of the W.V.P.A 20100201

Title: Synthesis of marine polycyclic polyethers via endo-selective epoxide-opening cascades.

Journal: Marine drugs 20100101

Title: Retrospective study of salinomycin toxicosis in 66 cats.

Journal: Veterinary medicine international 20100101

Title: Inhaled Anesthetics Promote Albumin Dimerization through Reciprocal Exchange of Subdomains.

Journal: Biochemistry research international 20100101

Title: Validation of a multi-residue liquid chromatography-tandem mass spectrometry confirmatory method for 10 anticoccidials in eggs according to Commission Decision 2002/657/EC.

Journal: Journal of chromatography. A 20091113

Title: Multi-residue confirmatory method for the determination of twelve coccidiostats in chicken liver using liquid chromatography tandem mass spectrometry.

Journal: Journal of chromatography. A 20091113

Title: The activity and compatibility of the antibiotic tiamulin with other drugs in poultry medicine--A review.

Journal: Poultry science 20091101

Title: [Determination of 5 polyether antibiotics in chicken tissues by liquid chromatography-electrospray ionization tandem mass spectrometry].

Journal: Se pu = Chinese journal of chromatography 20091101

Title: Effects of organophosphate phenyl saligenin phosphate and polyether carboxylic ionophore lasalocid on motor nerve conduction velocity, neuropathy target esterase enzyme activity, and clinical ataxia in chickens.

Journal: Toxicology mechanisms and methods 20090601

Title: Effects of ionophores and antibiotics on in vitro hydrogen sulfide production, dry matter disappearance, and total gas production in cultures with a steam-flaked corn-based substrate with or without added sulfur.

Journal: Journal of animal science 20090501

Title: Fast liquid chromatography/multiple-stage mass spectrometry of coccidiostats.

Journal: Rapid communications in mass spectrometry : RCM 20090501

Title: Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.

Journal: Bioscience, biotechnology, and biochemistry 20090101

Title: Monensin causes dose dependent inhibition of Mycobacterium avium subspecies paratuberculosis in radiometric culture.

Journal: Gut pathogens 20090101

Title: Responses of plasma acetate metabolism to hop (Humulus lupulus L.) in sheep.

Journal: International journal of biological sciences 20090101

Title: Giardia duodenalis in feedlot cattle from the central and western United States.

Journal: BMC veterinary research 20090101

Title: Analysis of specific mutants in the lasalocid gene cluster: evidence for enzymatic catalysis of a disfavoured polyether ring closure.

Journal: Chembiochem : a European journal of chemical biology 20081215

Title: Efficacy of lasalocid against coccidiosis in Chinese ring-necked pheasants.

Journal: Avian diseases 20081201

Title: Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis.

Journal: Journal of the American Chemical Society 20080917

Title: Determination of ionophore coccidiostats in feedingstuffs by liquid chromatography-tandem mass spectrometry Part I. Application to targeted feed.

Journal: Journal of pharmaceutical and biomedical analysis 20080805

Title: Doubly compensated multiplicity-edited HSQC experiments utilizing broadband inversion pulses.

Journal: Magnetic resonance in chemistry : MRC 20080701

Title: Antimicrobial use on 24 beef farms in Ontario.

Journal: Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20080301

Title: Determination of lasalocid sodium in animal feeds and premixes by reversed-phase liquid chromatography: collaborative study.

Journal: Journal of AOAC International 20080101

Title: Rubidium(I) monensinate dihydrate.

Journal: Acta crystallographica. Section E, Structure reports online 20080101

Title: Effects of lasalocid or monensin supplementation on digestion, ruminal fermentation, blood metabolites, and milk production of lactating dairy cows.

Journal: Journal of dairy science 20071201

Title: Sorption and degradation in soils of veterinary ionophore antibiotics: monensin and lasalocid.

Journal: Environmental toxicology and chemistry 20070801

Title: Mucosal mast cell proteases are involved in colonic permeability alterations and subsequent bacterial translocation in endotoxemic rats.

Journal: Shock (Augusta, Ga.) 20070701

Title: Changes in net portal nutrient flux in response to weaning transition and ionophore supplementation in dairy calves.

Journal: Journal of dairy science 20070301

Title: Efficacy of some anticoccidial drugs for treating coccidial enteritis of the common carp caused by Goussia carpelli (Apicomplexa: Eimeriidae).

Journal: Acta veterinaria Hungarica 20070301

Title: Effects of weaning and ionophore supplementation on selected blood metabolites and growth in dairy calves.

Journal: Journal of dairy science 20060901

Title: Efficacy of ionophores in cattle diets for mitigation of enteric methane.

Journal: Journal of animal science 20060701

Title: Simultaneous determination of four coccidiostats in eggs and broiler meat: validation of an LC-MS/MS method.

Journal: Food additives and contaminants 20060501

Title: Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression.

Journal: Molecular neurodegeneration 20060101

Title: Effect of ionophore supplementation on the incidence of Escherichia coli O157:H7 and Salmonella and antimicrobial susceptibility of fecal coliforms in Stocker cattle.

Journal: Foodborne pathogens and disease 20060101

Title: An Irish perspective on Cryptosporidium. Part 2.

Journal: Irish veterinary journal 20060101

Title: Incidence of residues of nine anticoccidials in eggs.

Journal: Food additives and contaminants 20051101

Title: The solution structure of a lasalocid A metal complex in lipophilic solvents.

Journal: Bioorganic & medicinal chemistry 20050901

Title: [Cryptosporidiosis in newborn calves in Ankara region: clinical, haematological findings and treatment with Lasalocid-NA].

Journal: DTW. Deutsche tierarztliche Wochenschrift 20050601

Title: A band-selective composite gradient: application to DQF-COSY.

Journal: Journal of magnetic resonance (San Diego, Calif. : 1997) 20050501

Title: A comparison of data analysis methods for determining gas phase stabilities by CID: alkali metal complexes of polyether ionophore antibiotics.

Journal: Journal of the American Society for Mass Spectrometry 20050501

Title: Comparison of copper speciation in estuarine water measured using analytical voltammetry and supported liquid membrane techniques.

Journal: Environmental science & technology 20050501

Title: Periodicity in collision-induced and remote-bond activation of alkali metal ions attached to polyether ionophores.

Journal: The Analyst 20050401

Title: The residue levels of narasin in eggs of laying hens fed with unmedicated and medicated feed.

Journal: Molecular nutrition & food research 20050101

Title: Determination of the ionophoric coccidiostats narasin, monensin, lasalocid and salinomycin in eggs by liquid chromatography/tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20050101

Title: Efficient and sensitive detection of residues of nine coccidiostats in egg and muscle by liquid chromatography-electrospray tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225

Title: Extending the limits of the selective 1D NOESY experiment with an improved selective TOCSY edited preparation function.

Journal: Journal of magnetic resonance (San Diego, Calif. : 1997) 20041201

Title: Development of multiclass methods for drug residues in eggs: silica SPE cleanup and LC-MS/MS analysis of ionophore and macrolide residues.

Journal: Journal of agricultural and food chemistry 20041117

Title: Ionophore taste preferences of dairy heifers.

Journal: Journal of animal science 20041101

Title: Production and health of pasture-fed dairy cattle following oral treatment with the ionophore lasalocid.

Journal: Journal of dairy science 20040901

Title: Accidental poisoning of 17 dogs with lasalocid.

Journal: The Veterinary record 20040807

Title: [Development of monoclonal-based enzyme-linked immunosorbent assay and immunochromatographic assay for lasalocid and semduramicin].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20040601

Title: Isolation and selection of ionophore-tolerant Eimeria precocious lines: E. tenella, E. maxima and E. acervulina.

Journal: Veterinary parasitology 20040206

Title: Susceptibility of Clostridium perfringens strains from broiler chickens to antibiotics and anticoccidials.

Journal: Avian pathology : journal of the W.V.P.A 20040201

Title: An alternative to antibiotic-based drugs in feed for enhancing performance of broilers grown on Eimeria spp.-infected litter.

Journal: Poultry science 20040101

Title: Rapid forensic selected reaction monitoring liquid chromatography/mass spectrometry determination of ionophore antibiotics found at toxic levels in animal feeds.

Journal: Journal of AOAC International 20040101

Title: Inhibition of resistance plasmid transfer in Escherichia coli by ionophores, chlortetracycline, bacitracin, and ionophore/antimicrobial combinations.

Journal: Avian diseases 20040101

Title: Effect of lasalocid on growth, blood gases, and nutrient utilization in dairy goats fed a high forage, low protein diet.

Journal: Journal of dairy science 20031201

Title: The susceptibility of ionophore-resistant Clostridium aminophilum F to other antibiotics.

Journal: The Journal of antimicrobial chemotherapy 20031001

Title: Suspected lasalocid poisoning in three dogs.

Journal: Veterinary and human toxicology 20031001

Title: Ionophores: their use as ruminant growth promotants and impact on food safety.

Journal: Current issues in intestinal microbiology 20030901

Title: Resistance to anticoccidial drugs of Dutch avian Eimeria spp. field isolates originating from 1996, 1999 and 2001.

Journal: Avian pathology : journal of the W.V.P.A 20030801

Title: Guanidinium receptors as enantioselective amino acid membrane carriers.

Journal: Journal of the American Chemical Society 20030709

Title: Effects of lasalocid on circulating concentrations of leptin and insulin-like growth factor-I and reproductive performance of postpartum Brahman cows.

Journal: Journal of animal science 20030601

Title: Effect of dietary supplementation with oregano essential oil on performance of broilers after experimental infection with Eimeria tenella.

Journal: Archiv fur Tierernahrung 20030401

Title: Effects of the antibiotic ionophores monensin, lasalocid, laidlomycin propionate and bambermycin on Salmonella and E. coli O157:H7 in vitro.

Journal: Journal of applied microbiology 20030101

Title: A functional observational battery for use in canine toxicity studies: development and validation.

Journal: International journal of toxicology 20030101

Title: Multinuclear NMR and FTIR studies of new polyoxaalkyl esters of lasalocid and their complexes with lithium and sodium cations.

Journal: Biopolymers 20021015

Title: [Effects of veterinary drugs on beta-hexosaminidase release from rat basophilic leukemia cells (RBL-2H3)].

Journal: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20021001

Title: Fragmentation studies on lasalocid acid by accurate mass electrospray mass spectrometry.

Journal: The Analyst 20020901

Title: Use of an adsorbed chiral selector in capillary LC-MS.

Journal: Chirality 20020801

Title: Lasalocid toxicosis is inadequately quantified for horses.

Journal: Veterinary and human toxicology 20020801

Title: Effect of lonophore supplementation on selected serum constituents of sheep consuming locoweed.

Journal: Veterinary and human toxicology 20020601

Title: The determination of 5 anticoccidial drugs (nicarbazin, lasalocid, monensin, salinomycin and narasin) in animal livers and eggs by liquid chromatography linked with tandem mass spectrometry (LC-MS-MS).

Journal: The Analyst 20020601

Title: Improved clean-up for the determination of lasalocid in 'difficult' food matrices.

Journal: Food additives and contaminants 20020101

Title: Effects of dietary rice bran, lasalocid, and sex of calf on postpartum reproduction in Brahman cows.

Journal: Journal of animal science 20011201

Title: Secretion of the trefoil factor TFF3 from the isolated vascularly perfused rat colon.

Journal: Regulatory peptides 20010915

Title: Nutritionally directed compensatory growth enhances heifer development and lactation potential.

Journal: Journal of dairy science 20010701

Title: Efficacy of diclazuril in comparison with chemical and ionophorous anticoccidials against Eimeria spp. in broiler chickens in floor pens.

Journal: Poultry science 20010401

Title: Ion pairing between Cl- or ClO4- and alkali metal complexes of ionophore antibiotics in organic solvents: a multinuclear NMR and FT-IR study.

Journal: Inorganic chemistry 20010326

Title: Improved agar diffusion method for detecting residual antimicrobial agents.

Journal: Journal of food protection 20010301

Title: 7Li-NMR and FTIR studies of lithium, potassium, rubidium, and cesium complexes with ionophore lasalocid in solution.

Journal: Biopolymers 20010101

Title: LC/MS confirmation of ionophores in animal feeds.

Journal: Journal of AOAC International 20010101

Title: Interaction of fluoroquinolones and certain ionophores in broilers: effect on blood levels and hepatic cytochrome p450 monooxygenase activity.

Journal: Drug metabolism and drug interactions 20010101

Title: Short-term exposure to membrane-active antibiotics inhibits Cryptosporidium parvum infection in cell culture.

Journal: Antimicrobial agents and chemotherapy 20001201

Title: Tamoxifen-induced enhancement of calcium signaling in glioma and MCF-7 breast cancer cells.

Journal: Cancer research 20001001

Title: Anticryptosporidial activity of ranalexin, lasalocid and azithromycin alone and in combination in cell lines.

Journal: The Journal of antimicrobial chemotherapy 20000301

Title: Assessment of drugs against Cryptosporidium parvum using a simple in vitro screening method.

Journal: FEMS microbiology letters 19990915

Title: In-vitro activities of paromomycin and lasalocid evaluated in combination against Cryptosporidium parvum.

Journal: The Journal of antimicrobial chemotherapy 19980201

Title: Efficacy of lasalocid against murine Pneumocystis carinii pneumonitis.

Journal: Antimicrobial agents and chemotherapy 19970101

Title: Efficacy of 101 antimicrobials and other agents on the development of Cryptosporidium parvum in vitro.

Journal: Annals of tropical medicine and parasitology 19961201

Title: Putative anticryptosporidial agents tested with an immunodeficient mouse model.

Journal: Antimicrobial agents and chemotherapy 19940401

Title: Anticryptosporidial activity of lasalocid and other ionophorous antibiotics in immunosuppressed rats.

Journal: The Journal of infectious diseases 19931201

Title: Assessment of candidate anticryptosporidial agents in an immunosuppressed rat model.

Journal: The Journal of infectious diseases 19930301

Title: Inhibitory effects of polyethers on human immunodeficiency virus replication.

Journal: Antimicrobial agents and chemotherapy 19920201

Title: Chemotherapeutic effect of azithromycin and lasalocid on Cryptosporidium infection in mice.

Journal: The Journal of protozoology 19910101

Title: Anti-cryptosporidial drug activity screened with an immunosuppressed rat model.

Journal: The Journal of protozoology 19910101

Title: Chen M, et al. Effect of monensin and lasalocid-sodium on the growth of methanogenic and rumen saccharolytic bacteria. Appl Environ Microbiol. 1979 Jul;38(1):72-7.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 25999-31-9
Tags:25999-31-9 Molecular Formula|25999-31-9 MDL|25999-31-9 SMILES|25999-31-9 Lasalocid