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2646-38-0,MFCD00065452
Catalog No.:AA002T8B

2646-38-0 | Cholan-24-oic acid, 3,7-dihydroxy-, monosodium salt, (3α,5β,7α)-

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500mg
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1g
≥ 98% (Titration)
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5g
≥ 98% (Titration)
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25g
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100g
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250g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002T8B
Chemical Name:
Cholan-24-oic acid, 3,7-dihydroxy-, monosodium salt, (3α,5β,7α)-
CAS Number:
2646-38-0
Molecular Formula:
C24H39NaO4
Molecular Weight:
414.5538
MDL Number:
MFCD00065452
SMILES:
O[C@@H]1CC[C@]2([C@@H](C1)C[C@H]([C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2[C@@H](CCC(=O)[O-])C)C)O)C.[Na+]
Properties
Computed Properties
 
Complexity:
612  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
10  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  

Literature

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Journal: Toxicology in vitro : an international journal published in association with BIBRA 20170301

Title: Alisol B 23-acetate protects against non-alcoholic steatohepatitis in mice via farnesoid X receptor activation.

Journal: Acta pharmacologica Sinica 20170101

Title: Obeticholic acid protects against carbon tetrachloride-induced acute liver injury and inflammation.

Journal: Toxicology and applied pharmacology 20170101

Title: UDCA and CDCA alleviate 17α-ethinylestradiol-induced cholestasis through PKA-AMPK pathways in rats.

Journal: Toxicology and applied pharmacology 20161115

Title: Obeticholic Acid: First Global Approval.

Journal: Drugs 20160801

Title: Chenodeoxycholic acid significantly impacts the expression of miRNAs and genes involved in lipid, bile acid and drug metabolism in human hepatocytes.

Journal: Life sciences 20160701

Title: Farnesoid X Receptor Protects against Kidney Injury in Uninephrectomized Obese Mice.

Journal: The Journal of biological chemistry 20160129

Title: The organic solute transporters alpha and beta are induced by hypoxia in human hepatocytes.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20150401

Title: Toxicity and intracellular accumulation of bile acids in sandwich-cultured rat hepatocytes: role of glycine conjugates.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20140301

Title: An improved synthesis of 6α-ethylchenodeoxycholic acid (6ECDCA), a potent and selective agonist for the Farnesoid X Receptor (FXR).

Journal: Steroids 20121101

Title: Testosterone and farnesoid X receptor agonist INT-747 counteract high fat diet-induced bladder alterations in a rabbit model of metabolic syndrome.

Journal: The Journal of steroid biochemistry and molecular biology 20121001

Title: Involvement of multiple elements in FXR-mediated transcriptional activation of FGF19.

Journal: The Journal of steroid biochemistry and molecular biology 20121001

Title: BASIC--a bile acid-sensitive ion channel highly expressed in bile ducts.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20121001

Title: Formation of tubules by p-tert-butylphenylamide derivatives of chenodeoxycholic and ursodeoxycholic acids in aqueous solution.

Journal: Steroids 20121001

Title: Effect of probiotics on serum bile acids in patients with ulcerative colitis.

Journal: Hepato-gastroenterology 20120901

Title: Inhibition of butyrate uptake by the primary bile salt chenodeoxycholic acid in intestinal epithelial cells.

Journal: Journal of cellular biochemistry 20120901

Title: Kinetics of bile salt binding to liposomes revealed by carboxyfluorescein release and mathematical modeling.

Journal: Journal of liposome research 20120901

Title: Discovery and optimization of 1,3,4-trisubstituted-pyrazolone derivatives as novel, potent, and nonsteroidal farnesoid X receptor (FXR) selective antagonists.

Journal: Journal of medicinal chemistry 20120823

Title: Clinical reasoning: a case of treatable spastic paraparesis.

Journal: Neurology 20120807

Title: Determination of binding affinity for chenodeoxycholate in equilibrium with sulfobutylether-β-cyclodextrin.

Journal: Journal of pharmaceutical sciences 20120801

Title: Farnesoid X receptor regulates vascular reactivity through nitric oxide mechanism.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20120801

Title: Chenodeoxycholic acid through a TGR5-dependent CREB signaling activation enhances cyclin D1 expression and promotes human endometrial cancer cell proliferation.

Journal: Cell cycle (Georgetown, Tex.) 20120715

Title: Putative irreversible inhibitors of the human sodium-dependent bile acid transporter (hASBT; SLC10A2) support the role of transmembrane domain 7 in substrate binding/translocation.

Journal: Pharmaceutical research 20120701

Title: Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120701

Title: Activation of farnesoid X receptor attenuates liver injury in systemic lupus erythematosus.

Journal: Rheumatology international 20120601

Title: Probiotics decreased the bioavailability of the bile acid analog, monoketocholic acid, when coadministered with gliclazide, in healthy but not diabetic rats.

Journal: European journal of drug metabolism and pharmacokinetics 20120601

Title: Molecular interactions between selected sodium salts of bile acids and morphine hydrochloride.

Journal: Colloids and surfaces. B, Biointerfaces 20120601

Title: Progressive familial intrahepatic cholestasis and inborn errors of bile acid synthesis.

Journal: Clinics and research in hepatology and gastroenterology 20120601

Title: [Progress in the ligands and their complex structures of farnesoid X receptor].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20120601

Title: The effect of physiological concentrations of bile acids on in vitro growth of Mycobacterium tuberculosis.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20120523

Title: Molecular dynamics simulations on the aggregation behavior of indole type organic dye molecules in dye-sensitized solar cells.

Journal: Journal of molecular modeling 20120501

Title: Cytochrome P450s in the synthesis of cholesterol and bile acids--from mouse models to human diseases.

Journal: The FEBS journal 20120501

Title: Biophysical investigations into the interactions of endotoxins with bile acids.

Journal: Innate immunity 20120401

Title: Unusual binding of ursodeoxycholic acid to ileal bile acid binding protein: role in activation of FXRα.

Journal: Journal of lipid research 20120401

Title: Multiple functions of a multi-component mating pheromone in sea lamprey Petromyzon marinus.

Journal: Journal of fish biology 20120301

Title: A tea catechin, epigallocatechin-3-gallate, is a unique modulator of the farnesoid X receptor.

Journal: Toxicology and applied pharmacology 20120115

Title: Conicasterol E, a small heterodimer partner sparing farnesoid X receptor modulator endowed with a pregnane X receptor agonistic activity, from the marine sponge Theonella swinhoei.

Journal: Journal of medicinal chemistry 20120112

Title: The bile steroid chenodeoxycholate is a potent antagonist at NMDA and GABA(A) receptors.

Journal: Neuroscience letters 20120111

Title: Three siblings with Cerebrotendinous Xanthomatosis: a novel mutation in the CYP27A1 gene.

Journal: European journal of medical genetics 20120101

Title: Testosterone protects from metabolic syndrome-associated prostate inflammation: an experimental study in rabbit.

Journal: The Journal of endocrinology 20120101

Title: Eicosapentaenoic acid and docosahexaenoic acid synergistically attenuate bile acid-induced hepatocellular apoptosis.

Journal: JPEN. Journal of parenteral and enteral nutrition 20120101

Title: Mechanistic studies of the effect of bile salts on rhodamine 123 uptake into RBE4 cells.

Journal: Molecular pharmaceutics 20120101

Title: Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20120101

Title: Spores of Clostridium difficile clinical isolates display a diverse germination response to bile salts.

Journal: PloS one 20120101

Title: Oral gallstone dissolution therapies.

Journal: Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses 20120101

Title: Bile acids specifically increase hepatitis C virus RNA-replication.

Journal: PloS one 20120101

Title: Targeting bile acids in the treatment of constipation.

Journal: Expert review of gastroenterology & hepatology 20111201

Title: Effect of twice-daily oral administration of hydrocortisone on the bile acids composition of gallbladder bile in dogs.

Journal: American journal of veterinary research 20111201

Title: Bile acids promote HCV replication through the EGFR/ERK pathway in replicon-harboring cells.

Journal: Intervirology 20111001

Title: Deoxycholic and chenodeoxycholic bile acids induce apoptosis via oxidative stress in human colon adenocarcinoma cells.

Journal: Apoptosis : an international journal on programmed cell death 20111001

Title: Primary bile acid therapy during pregnancy in patients with 3β-hydroxy-Δ5 -C27 -steroid oxidoreductase deficiency.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20111001

Title: Farnesoid X receptor inhibits tamoxifen-resistant MCF-7 breast cancer cell growth through downregulation of HER2 expression.

Journal: Oncogene 20110929

Title: High-dose ursodeoxycholic acid is associated with the development of colorectal neoplasia in patients with ulcerative colitis and primary sclerosing cholangitis.

Journal: The American journal of gastroenterology 20110901

Title: Monitoring of 7α-hydroxy-4-cholesten-3-one during therapy of cerebrotendinous xanthomatosis: a case report.

Journal: Chemistry and physics of lipids 20110901

Title: Farnesoid X receptor activation by chenodeoxycholic acid induces detoxifying enzymes through AMP-activated protein kinase and extracellular signal-regulated kinase 1/2-mediated phosphorylation of CCAAT/enhancer binding protein β.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20110801

Title: Farnesoid X receptor agonist for the treatment of liver and metabolic disorders: focus on 6-ethyl-CDCA.

Journal: Mini reviews in medicinal chemistry 20110801

Title: Cerebrotendinous xanthomatosis: a treatable disease with juvenile cataracts as a presenting sign.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20110801

Title: Chenodeoxycholic acid stabilization of LDL receptor mRNA depends on 3'-untranslated region and AU-rich element-binding protein.

Journal: Biochemical and biophysical research communications 20110603

Title: Visualisation of treatment response in a case of cerebrotendinous xanthomatosis.

Journal: Journal of neurology, neurosurgery, and psychiatry 20110601

Title: SHP-dependent and -independent induction of peroxisome proliferator-activated receptor-γ by the bile acid sensor farnesoid X receptor counter-regulates the pro-inflammatory phenotype of liver myofibroblasts.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20110601

Title: Clinical relevance and neurophysiological correlates of spasticity in cerebrotendinous xanthomatosis.

Journal: Journal of neurology 20110501

Title: Farnesoid X receptor agonists for primary biliary cirrhosis.

Journal: Current opinion in gastroenterology 20110501

Title: Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease.

Journal: Gut 20110401

Title: Differential disposition of chenodeoxycholic acid versus taurocholic acid in response to acute troglitazone exposure in rat hepatocytes.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110401

Title: Low levels of bile acids increase bacterial uptake in colonic biopsies from patients with collagenous colitis in remission.

Journal: Alimentary pharmacology & therapeutics 20110401

Title: Synthesis and in vitro evaluation of gabapentin prodrugs that target the human apical sodium-dependent bile acid transporter (hASBT).

Journal: Journal of pharmaceutical sciences 20110301

Title: Engineered three-dimensional liver mimics recapitulate critical rat-specific bile acid pathways.

Journal: Tissue engineering. Part A 20110301

Title: Pathophysiological relevance of apical large-conductance Ca²+-activated potassium channels in pancreatic duct epithelial cells.

Journal: Gut 20110301

Title: Gas chromatography-mass spectrometry-based simultaneous quantitative analytical method for urinary oxysterols and bile acids in rats.

Journal: Analytical biochemistry 20110115

Title: Screening for novel antibacterial agents based on the activities of compounds on metabolism of Escherichia coli: a microcalorimetric study.

Journal: Journal of hazardous materials 20110115

Title: Effects of farnesoid X receptor on the expression of the fatty acid synthetase and hepatic lipase.

Journal: Molecular biology reports 20110101

Title: Non-conjugated chenodeoxycholate induces severe mitochondrial damage and inhibits bicarbonate transport in pancreatic duct cells.

Journal: Gut 20110101

Title: The crystal structures of the Salmonella type III secretion system tip protein SipD in complex with deoxycholate and chenodeoxycholate.

Journal: Protein science : a publication of the Protein Society 20110101

Title: Neuromuscular abnormality and autonomic dysfunction in patients with cerebrotendinous xanthomatosis.

Journal: BMC neurology 20110101

Title: Transformation of chenodeoxycholic acid by thermophilic Geobacillus stearothermophilus.

Journal: Biotechnology and applied biochemistry 20110101

Title: Cerebrotendinous xanthomatosis: a rare cause of spinocerebellar syndrome.

Journal: Neurologia i neurochirurgia polska 20110101

Title: Structural determinants for transport across the intestinal bile acid transporter using C-24 bile acid conjugates.

Journal: Molecular pharmaceutics 20101206

Title: Structural requirements of the ASBT by 3D-QSAR analysis using aminopyridine conjugates of chenodeoxycholic acid.

Journal: Bioconjugate chemistry 20101117

Title: Application of near infrared spectroscopy for rapid analysis of intermediates of Tanreqing injection.

Journal: Journal of pharmaceutical and biomedical analysis 20101102

Title: Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice.

Journal: Journal of lipid research 20101101

Title: Chenodeoxycholate in females with irritable bowel syndrome-constipation: a pharmacodynamic and pharmacogenetic analysis.

Journal: Gastroenterology 20101101

Title: The influence of NaCl on hydrophobicity of selected, pharmacologically active bile acids expressed with chromatographic retention index and critical micellar concentration.

Journal: Colloids and surfaces. B, Biointerfaces 20101101

Title: Inflammatory mediators of esophagitis alter p27 Kip1 expression in esophageal epithelial cells.

Journal: Journal of pediatric gastroenterology and nutrition 20101101

Title: Analysis of serum bile acids by isotope dilution-mass spectrometry to assess the performance of routine total bile acid methods.

Journal: Annals of clinical biochemistry 20101101

Title: Inhibiting the initiation of Clostridium difficile spore germination using analogs of chenodeoxycholic acid, a bile acid.

Journal: Journal of bacteriology 20101001

Title: Modelling phase transition kinetics of chenodeoxycholic acid with the Runge-Kutta method.

Journal: Journal of pharmaceutical and biomedical analysis 20100921

Title: Molecular genetic and bile acid profiles in two Japanese patients with 3beta-hydroxy-DELTA5-C27-steroid dehydrogenase/isomerase deficiency.

Journal: Pediatric research 20100901

Title: Two time-point assessment of bile acid kinetics in humans using stable isotopes.

Journal: Isotopes in environmental and health studies 20100901

Title: Construction of confidence regions for isotopic abundance patterns in LC/MS data sets for rigorous determination of molecular formulas.

Journal: Analytical chemistry 20100901

Title: Synthesis and in vitro evaluation of potential sustained release prodrugs via targeting ASBT.

Journal: International journal of pharmaceutics 20100830

Title: Retinoic acid represses CYP7A1 expression in human hepatocytes and HepG2 cells by FXR/RXR-dependent and independent mechanisms.

Journal: Journal of lipid research 20100801

Title: A putative role of micro RNA in regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes.

Journal: Journal of lipid research 20100801

Title: 3β-hydroxy-Δ⁵-C₂₇-steroid dehydrogenase/isomerase deficiency in a patient who underwent oral bile acid therapy for 10 years and delivered two healthy infants.

Journal: Pediatrics international : official journal of the Japan Pediatric Society 20100801

Title: Farnesoid X receptor activation prevents the development of vascular calcification in ApoE-/- mice with chronic kidney disease.

Journal: Circulation research 20100625

Title: Hydrophobicity and haemolytic potential of oxo derivatives of cholic, deoxycholic and chenodeoxycholic acids.

Journal: Steroids 20100601

Title: Titration of bile acid supplements in 3beta-hydroxy-Delta 5-C27-steroid dehydrogenase/isomerase deficiency.

Journal: Journal of pediatric gastroenterology and nutrition 20100601

Title: Pharmacotherapy of cholestatic liver diseases.

Journal: Journal of digestive diseases 20100601

Title: FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats.

Journal: Journal of lipid research 20100401

Title: alpha(1)-fetoprotein transcription factor (FTF)/liver receptor homolog-1 (LRH-1) is an essential lipogenic regulator.

Journal: Biochimica et biophysica acta 20100401

Title: Salivary chenodeoxycholic acid and its glycine-conjugate: their determination method using LC-MS/MS and variation of their concentrations with increased saliva flow rate.

Journal: Steroids 20100401

Title: Regulation of the human bile acid UDP-glucuronosyltransferase 1A3 by the farnesoid X receptor and bile acids.

Journal: Journal of hepatology 20100401

Title: Cerebrotendinous xanthomatosis presenting with severe externalized disorder: improvement after one year of treatment with chenodeoxycholic Acid.

Journal: CNS spectrums 20100401

Title: Identification of farnesoid X receptor modulators by a fluorescence polarization-based interaction assay.

Journal: Analytical biochemistry 20100315

Title: Oleanolic acid is a selective farnesoid X receptor modulator.

Journal: Phytotherapy research : PTR 20100301

Title: Impacts of different promoters on the mammalian one-hybrid assay for detecting nuclear receptor agonists.

Journal: Analytical and bioanalytical chemistry 20100301

Title: Farnesoid X receptor, through the binding with steroidogenic factor 1-responsive element, inhibits aromatase expression in tumor Leydig cells.

Journal: The Journal of biological chemistry 20100219

Title: Upregulation of early growth response factor-1 by bile acids requires mitogen-activated protein kinase signaling.

Journal: Toxicology and applied pharmacology 20100215

Title: Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain?

Journal: The Journal of biological chemistry 20100212

Title: Effects of chenodeoxycholate and a bile acid sequestrant, colesevelam, on intestinal transit and bowel function.

Journal: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20100201

Title: Regulation of diurnal variation of cholesterol 7alpha-hydroxylase (CYP7A1) activity in healthy subjects.

Journal: Physiological research 20100101

Title: Variable clinical spectrum of the most common inborn error of bile acid metabolism--3beta-hydroxy-Delta 5-C27-steroid dehydrogenase deficiency.

Journal: Journal of pediatric gastroenterology and nutrition 20100101

Title: Plasma bile acid concentrations in patients with human immunodeficiency virus infection receiving protease inhibitor therapy: possible implications for hepatotoxicity.

Journal: Pharmacotherapy 20100101

Title: Transport of estrone 3-sulfate mediated by organic anion transporter OATP4C1: estrone 3-sulfate binds to the different recognition site for digoxin in OATP4C1.

Journal: Drug metabolism and pharmacokinetics 20100101

Title: Liver X receptor agonist methyl-3β-hydroxy-5α,6α-epoxycholanate attenuates atherosclerosis in apolipoprotein E knockout mice without increasing plasma triglyceride.

Journal: Pharmacology 20100101

Title: The farnesoid X receptor modulates renal lipid metabolism and diet-induced renal inflammation, fibrosis, and proteinuria.

Journal: American journal of physiology. Renal physiology 20091201

Title: Developments in bile acid kinetic measurements using (13)C and (2)H: 10(5) times improved sensitivity during the last 40 years.

Journal: Isotopes in environmental and health studies 20091201

Title: Determination of critical micellar concentrations of two monoketo derivatives of cholic acid.

Journal: Colloids and surfaces. B, Biointerfaces 20091101

Title: CFTR expression but not Cl- transport is involved in the stimulatory effect of bile acids on apical Cl-/HCO3- exchange activity in human pancreatic duct cells.

Journal: Pancreas 20091101

Title: Bile acids and metabolic regulation: mechanisms and clinical responses to bile acid sequestration.

Journal: Diabetes care 20091101

Title: Modulation of bile acid metabolism by 1alpha-hydroxyvitamin D3 administration in mice.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20091001

Title: Albumin dialysis molecular adsorbents recirculating system: impact of dialysate albumin concentration on detoxification efficacy.

Journal: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20091001

Title: Cerebrotendinous xanthomatosis: a treatable neurodegenerative disease.

Journal: The Journal of the Association of Physicians of India 20091001

Title: Fluorescence properties of trans-ethyl-p-(dimethylamino) cinnamate in presence of bile acid host.

Journal: Journal of photochemistry and photobiology. B, Biology 20090904

Title: Bile acids inhibit NAD+-dependent 15-hydroxyprostaglandin dehydrogenase transcription in colonocytes.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20090901

Title: Effects of essential fatty acid deficiency on enterohepatic circulation of bile salts in mice.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20090901

Title: Cerebrotendinous xanthomatosis (CTX): a treatable lipid storage disease.

Journal: Pediatric endocrinology reviews : PER 20090901

Title: Inhibition of nucleostemin upregulates CDX2 expression in HT29 cells in response to bile acid exposure: implications in the pathogenesis of Barrett's esophagus.

Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20090801

Title: Relative inhibitory activity of bile acids against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation, and chenodeoxycholic acid inhibition of tumour promotion in mouse skin two-stage carcinogenesis.

Journal: The Journal of pharmacy and pharmacology 20090801

Title: Oromandibular dystonia as a complication of cerebrotendinous xanthomatosis.

Journal: Movement disorders : official journal of the Movement Disorder Society 20090715

Title: Bile acid aspiration in suspected ventilator-associated pneumonia.

Journal: Chest 20090701

Title: Bile acids inhibit duodenal secretin expression via orphan nuclear receptor small heterodimer partner (SHP).

Journal: American journal of physiology. Gastrointestinal and liver physiology 20090701

Title: Monoketocholate can decrease transcellular permeation of methotrexate across Caco-2 cell monolayers and reduce its intestinal absorption in rat.

Journal: The Journal of pharmacy and pharmacology 20090701

Title: Association between farnesoid X receptor expression and cell proliferation in estrogen receptor-positive luminal-like breast cancer from postmenopausal patients.

Journal: Breast cancer research and treatment 20090601

Title: Efficacy on anaplastic thyroid carcinoma of valproic acid alone or in combination with doxorubicin, a synthetic chenodeoxycholic acid derivative, or lactacystin.

Journal: International journal of oncology 20090501

Title: [Expression and regulation of megalin in gallbladder mucosa associated with cholesterol gallstone disease].

Journal: Zhonghua yi xue za zhi 20090428

Title: Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin-proteasomal degradation.

Journal: Genes & development 20090415

Title: [The right medicine for cerebrotendinous xanthomatosis].

Journal: Nederlands tijdschrift voor geneeskunde 20090411

Title: FXR promotes endothelial cell motility through coordinated regulation of FAK and MMP-9.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20090401

Title: Conversion of cholic acid and chenodeoxycholic acid into their 7-oxo derivatives by Bacteroides intestinalis AM-1 isolated from human feces.

Journal: FEMS microbiology letters 20090401

Title: Bile salts control the antimicrobial peptide cathelicidin through nuclear receptors in the human biliary epithelium.

Journal: Gastroenterology 20090401

Title: ATP8B1 deficiency disrupts the bile canalicular membrane bilayer structure in hepatocytes, but FXR expression and activity are maintained.

Journal: Gastroenterology 20090301

Title: Hematopoietically expressed homeobox is a target gene of farnesoid X receptor in chenodeoxycholic acid-induced liver hypertrophy.

Journal: Hepatology (Baltimore, Md.) 20090301

Title: Antiatherosclerotic effect of farnesoid X receptor.

Journal: American journal of physiology. Heart and circulatory physiology 20090201

Title: Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression.

Journal: Hepatology (Baltimore, Md.) 20090101

Title: Low retinol levels differentially modulate bile salt-induced expression of human and mouse hepatic bile salt transporters.

Journal: Hepatology (Baltimore, Md.) 20090101

Title: Chronic diarrhea and juvenile cataracts: think cerebrotendinous xanthomatosis and treat.

Journal: Pediatrics 20090101

Title: Bear bile: dilemma of traditional medicinal use and animal protection.

Journal: Journal of ethnobiology and ethnomedicine 20090101

Title: Biphasic regulation of cell death and survival by hydrophobic bile acids in HCT116 cells.

Journal: Nutrition and cancer 20090101

Title: Cefotaxime pharmacokinetics after oral application in the form of 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate microvesicles in rat.

Journal: European journal of drug metabolism and pharmacokinetics 20090101

Title: Gliclazide reduces MKC intestinal transport in healthy but not diabetic rats.

Journal: European journal of drug metabolism and pharmacokinetics 20090101

Title: Effect of 12-monoketocholic acid on modulation of analgesic action of morphine and tramadol.

Journal: European journal of drug metabolism and pharmacokinetics 20090101

Title: A new bile acid from the bile of Anser anser.

Journal: Natural product research 20090101

Title: Transport assays and permeability in pathogenic mycobacteria.

Journal: Methods in molecular biology (Clifton, N.J.) 20090101

Title: Elevated cholesterol precursors other than cholestanol can also be a hallmark for CTX.

Journal: Journal of inherited metabolic disease 20081201

Title: Physical and chemical factors influencing the germination of Clostridium difficile spores.

Journal: Journal of applied microbiology 20081201

Title: Synthetic chenodeoxycholic acid derivative, HS-1200, induces apoptosis of human hepatoma cells via a mitochondrial pathway.

Journal: Cancer letters 20081108

Title: Altered bile acid metabolism in childhood functional constipation: inactivation of secretory bile acids by sulfation in a subset of patients.

Journal: Journal of pediatric gastroenterology and nutrition 20081101

Title: FXRalpha down-regulates LXRalpha signaling at the CETP promoter via a common element.

Journal: Molecules and cells 20081031

Title: A chenodeoxycholic derivative, HS-1200, induces apoptosis and cell cycle modulation via Egr-1 gene expression control on human hepatoma cells.

Journal: Cancer letters 20081018

Title: Identification of human hepatic cytochrome p450 enzymes involved in the biotransformation of cholic and chenodeoxycholic acid.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20081001

Title: New lithocholic and chenodeoxycholic piperazinylcarboxamides with antiproliferative and pro-apoptotic effects on human cancer cell lines.

Journal: Bioorganic & medicinal chemistry 20080915

Title: The synthesis of MP-CDCA conjugates and dissolution kinetics of model cholesterol gallstones.

Journal: Acta biomaterialia 20080901

Title: Bile acids repress E-cadherin through the induction of Snail and increase cancer invasiveness in human hepatobiliary carcinoma.

Journal: Cancer science 20080901

Title: Effects of bile acids on pancreatic ductal bicarbonate secretion in guinea pig.

Journal: Gut 20080801

Title: Critical micellar concentrations of keto derivatives of selected bile acids: thermodynamic functions of micelle formation.

Journal: Colloids and surfaces. B, Biointerfaces 20080715

Title: Teaching neuroimage: cerebrotendinous xanthomatosis.

Journal: Neurology 20080708

Title: Bile acid levels are increased in the liver of patients with steatohepatitis.

Journal: European journal of gastroenterology & hepatology 20080601

Title: [Effects of farnesoid X receptor ligand on the metabolism of bile acids in rats with estrogen-induced intrahepatic cholestasis of pregnancy].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20080501

Title: [Analysis of bile acid-related proteins by mass spectrometry].

Journal: Rinsho byori. The Japanese journal of clinical pathology 20080501

Title: Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma.

Journal: Cancer research 20080415

Title: Bile acids modulate tight junction structure and barrier function of Caco-2 monolayers via EGFR activation.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20080401

Title: Activation of the farnesoid X receptor represses PCSK9 expression in human hepatocytes.

Journal: FEBS letters 20080319

Title: Influence of the semisynthetic bile acid MKC on the ileal permeation of gliclazide in vitro in healthy and diabetic rats treated with probiotics.

Journal: Methods and findings in experimental and clinical pharmacology 20080301

Title: Rapid screening of antineoplastic candidates for the human organic anion transporter OATP1B3 substrates using fluorescent probes.

Journal: Cancer letters 20080218

Title: FXR-mediated regulation of angiotensin type 2 receptor expression in vascular smooth muscle cells.

Journal: Cardiovascular research 20080201

Title: Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells.

Journal: British journal of pharmacology 20080201

Title: Systematic studies on the paracellular permeation of model permeants and oligonucleotides in the rat small intestine with chenodeoxycholate as enhancer.

Journal: Journal of pharmaceutical sciences 20080101

Title: The use of High Performance Thin-Layer Chromatography to determine the role of membrane lipid composition in bile salt-induced kidney cell damage.

Journal: Journal of pharmacological and toxicological methods 20080101

Title: Spectral-resolved gene technology for multiplexed bioluminescence and high-content screening.

Journal: Analytical chemistry 20080101

Title: Effect of colonic bacterial metabolites on Caco-2 cell paracellular permeability in vitro.

Journal: Nutrition and cancer 20080101

Title: Farnesoid X receptor induces GLUT4 expression through FXR response element in the GLUT4 promoter.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

Title: Influence of sodium monoketocholate on the hypolipidemic activity of lovastatin in healthy and diabetic rats.

Journal: European journal of drug metabolism and pharmacokinetics 20080101

Title: Influence of the semisynthetic bile acid (MKC) on the ileal permeation of gliclazide in healthy and diabetic rats.

Journal: Pharmacological reports : PR 20080101

Title: Bile composition in Alagille Syndrome and PFIC patients having Partial External Biliary Diversion.

Journal: BMC gastroenterology 20080101

Title: The influence of 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate on gliclazide pharmacokinetics and glucose levels in a rat model of diabetes.

Journal: European journal of drug metabolism and pharmacokinetics 20080101

Title: Deoxycholic acid induces the overexpression of intestinal mucin, MUC2, via NF-kB signaling pathway in human esophageal adenocarcinoma cells.

Journal: BMC cancer 20080101

Title: Regulation of hepatic bile acid transporters Ntcp and Bsep expression.

Journal: Biochemical pharmacology 20071203

Title: Chenodeoxycholic acid suppresses the activation of acetyl-coenzyme A carboxylase-alpha gene transcription by the liver X receptor agonist T0-901317.

Journal: Journal of lipid research 20071201

Title: Farnesoid x receptor ligands inhibit vascular smooth muscle cell inflammation and migration.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20071201

Title: Synthesis, characterization, and receptor interaction profiles of enantiomeric bile acids.

Journal: Journal of medicinal chemistry 20071129

Title: Structural and dynamic determinants of ligand binding in the ternary complex of chicken liver bile acid binding protein with two bile salts revealed by NMR.

Journal: Biochemistry 20071106

Title: Novel cytotoxic agents from an unexpected source: bile acids and ovarian tumor apoptosis.

Journal: Gynecologic oncology 20071101

Title: Activation of nuclear factor (erythroid-2 like) factor 2 by toxic bile acids provokes adaptive defense responses to enhance cell survival at the emergence of oxidative stress.

Journal: Molecular pharmacology 20071101

Title: Protective effect of n-3 polyunsaturated fatty acid on primary culture of rat hepatocytes.

Journal: Journal of gastroenterology and hepatology 20071101

Title: Perinatal bile acid metabolism: bile acid analysis of meconium of preterm and full-term infants.

Journal: Journal of gastroenterology 20071101

Title: Protective effects of ursodeoxycholic acid on chenodeoxycholic acid-induced liver injury in hamsters.

Journal: World journal of gastroenterology 20071007

Title: Dihydroxy bile acids increase mucosal permeability and bacterial uptake in human colon biopsies.

Journal: Scandinavian journal of gastroenterology 20071001

Title: A novel variant of ileal bile acid binding protein is up-regulated through nuclear factor-kappaB activation in colorectal adenocarcinoma.

Journal: Cancer research 20071001

Title: Cerebrotendinous xanthomatosis: a treatable cause of metabolic ataxia.

Journal: The Journal of the Association of Physicians of India 20070901

Title: [Cerebrotendinous xanthomatosis].

Journal: Deutsche medizinische Wochenschrift (1946) 20070729

Title: Adaptive response to increased bile acids: induction of MDR1 gene expression and P-glycoprotein activity in renal epithelial cells.

Journal: Pflugers Archiv : European journal of physiology 20070701

Title: Human cecal bile acids: concentration and spectrum.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20070701

Title: Rifampicin-induced CYP3A4 activation in CTX patients cannot replace chenodeoxycholic acid treatment.

Journal: Biochimica et biophysica acta 20070701

Title: Downregulation of p63 upon exposure to bile salts and acid in normal and cancer esophageal cells in culture.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20070701

Title: Overexpression of the cholesterol-binding protein MLN64 induces liver damage in the mouse.

Journal: World journal of gastroenterology 20070614

Title: Bile acids and lipoprotein metabolism: effects of cholestyramine and chenodeoxycholic acid on human hepatic mRNA expression.

Journal: Biochemical and biophysical research communications 20070608

Title: Ontogenic development-associated changes in the expression of genes involved in rat bile acid homeostasis.

Journal: Journal of lipid research 20070601

Title: In vivo imaging of farnesoid X receptor activity reveals the ileum as the primary bile acid signaling tissue.

Journal: Molecular endocrinology (Baltimore, Md.) 20070601

Title: Crystal structure of chenodeoxycholic acid, ursodeoxycholic acid and their two 3beta,7alpha- and 3beta,7beta-dihydroxy epimers.

Journal: Steroids 20070601

Title: Can pigment gallstones be induced by biliary stricture and prevented by medicine in Guinea pigs?

Journal: World journal of gastroenterology 20070521

Title: A novel chenodeoxycholic derivative HS-1200 enhances radiation-induced apoptosis in MCF-7 cells.

Journal: Oncology reports 20070401

Title: Why bile acid glucuronidation is a minor pathway for conjugation of endogenous bile acids in man.

Journal: Hepatology (Baltimore, Md.) 20070401

Title: [Preparation and antitussive, expectorant and antiasthmatic activities of verticinone-bile acids salts].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070301

Title: Bile acid-mediated thrombospondin-1 induction in hepatocytes leads to transforming growth factor-beta-dependent hepatic stellate cell activation.

Journal: Biochemical and biophysical research communications 20070223

Title: Analysis of bile acid-induced regulation of FXR target genes in human liver slices.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20070201

Title: Bile acid-induced secretion in polarized monolayers of T84 colonic epithelial cells: Structure-activity relationships.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20070101

Title: Removal of bile acids by two different extracorporeal liver support systems in acute-on-chronic liver failure.

Journal: ASAIO journal (American Society for Artificial Internal Organs : 1992) 20070101

Title: Bioavailability and hypoglycemic activity of the semisynthetic bile acid salt, sodium 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate, in healthy and diabetic rats.

Journal: European journal of drug metabolism and pharmacokinetics 20070101

Title: Chenodeoxycholic acid and taurochenodexycholic acid induce anti-apoptotic cIAP-1 expression in human hepatocytes.

Journal: Journal of gastroenterology and hepatology 20061201

Title: Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man.

Journal: Journal of internal medicine 20061201

Title: Decreased glucagon responsiveness by bile acids: a role for protein kinase Calpha and glucagon receptor phosphorylation.

Journal: Endocrinology 20061101

Title: Human UDP-glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver.

Journal: Hepatology (Baltimore, Md.) 20061101

Title: The farnesoid X receptor promotes adipocyte differentiation and regulates adipose cell function in vivo.

Journal: Molecular pharmacology 20061001

Title: Presenile cataract: consider cholestanol.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20061001

Title: The nuclear hormone receptor farnesoid X receptor (FXR) is activated by androsterone.

Journal: Endocrinology 20060901

Title: Biphasic regulation by bile acids of dermal fibroblast proliferation through regulation of cAMP production and COX-2 expression level.

Journal: American journal of physiology. Cell physiology 20060901

Title: Two loci on chromosome 9 control bile acid composition: evidence that a strong candidate gene, Cyp8b1, is not the culprit.

Journal: Journal of lipid research 20060901

Title: Chenodeoxycholic acid stimulates the progression of human esophageal cancer cells: A possible mechanism of angiogenesis in patients with esophageal cancer.

Journal: International journal of cancer 20060815

Title: Identification of a lead pharmacophore for the development of potent nuclear receptor modulators as anticancer and X syndrome disease therapeutic agents.

Journal: Bioorganic & medicinal chemistry letters 20060815

Title: Suppression of bile acid synthesis by thyroid hormone in primary human hepatocytes.

Journal: World journal of gastroenterology 20060807

Title: Chenodeoxycholic acid-mediated activation of the farnesoid X receptor negatively regulates hydroxysteroid sulfotransferase.

Journal: Drug metabolism and pharmacokinetics 20060801

Title: A simple and general strategy for the design of fluorescent cation sensor beads.

Journal: Organic letters 20060720

Title: Back door modulation of the farnesoid X receptor: design, synthesis, and biological evaluation of a series of side chain modified chenodeoxycholic acid derivatives.

Journal: Journal of medicinal chemistry 20060713

Title: Identification of a novel bile acid in swans, tree ducks, and geese: 3alpha,7alpha,15alpha-trihydroxy-5beta-cholan-24-oic acid.

Journal: Journal of lipid research 20060701

Title: Interaction of native bile acids with human apical sodium-dependent bile acid transporter (hASBT): influence of steroidal hydroxylation pattern and C-24 conjugation.

Journal: Pharmaceutical research 20060701

Title: Effects of chenodeoxycholic acid and deoxycholic acid on cholesterol absorption and metabolism in humans.

Journal: Translational research : the journal of laboratory and clinical medicine 20060701

Title: Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3.

Journal: Journal of lipid research 20060601

Title: Plasma levels of ursodeoxycholic acid in black bears, Ursus americanus: seasonal changes.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20060601

Title: Bile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cells.

Journal: Hepatology (Baltimore, Md.) 20060601

Title: Single-step analysis of individual conjugated bile acids in human bile using 1H NMR spectroscopy.

Journal: Lipids 20060601

Title: Bile acid-mediated induction of cyclooxygenase-2 and Mcl-1 in hepatic stellate cells.

Journal: Biochemical and biophysical research communications 20060421

Title: Exploitation of the alcohol dehydrogenase-acetone NADP-regeneration system for the enzymatic preparative-scale production of 12-ketochenodeoxycholic acid.

Journal: Biotechnology and bioengineering 20060420

Title: Could steroids mask the diagnosis of cerebrotendinous xanthomatosis?

Journal: Journal of the neurological sciences 20060415

Title: 11Beta-hydroxysteroid dehydrogenase type 2 and the regulation of surfactant protein A by dexamethasone metabolites.

Journal: American journal of physiology. Endocrinology and metabolism 20060401

Title: Activation of the farnesoid X receptor improves lipid metabolism in combined hyperlipidemic hamsters.

Journal: American journal of physiology. Endocrinology and metabolism 20060401

Title: Bile acid profiles by capillary electrophoresis in intrahepatic cholestasis of pregnancy.

Journal: Clinical science (London, England : 1979) 20060401

Title: Fish oil increases bile acid synthesis in male patients with hypertriglyceridemia.

Journal: The Journal of nutrition 20060401

Title: Hepatocyte nuclear factor-4alpha plays pivotal roles in the regulation of mouse carboxylesterase 2 gene transcription in mouse liver.

Journal: Archives of biochemistry and biophysics 20060315

Title: Modulation of cholesterol metabolism by the green tea polyphenol (-)-epigallocatechin gallate in cultured human liver (HepG2) cells.

Journal: Journal of agricultural and food chemistry 20060308

Title: The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-alpha and -beta genes.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20060301

Title: Bile acid transport and metabolism in rat liver slices.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20060301

Title: 1,25-dihydroxyvitamin D3 and its receptor inhibit the chenodeoxycholic acid-dependent transactivation by farnesoid X receptor.

Journal: The Journal of endocrinology 20060301

Title: Nuclear receptors, bile-acid detoxification, and cholestasis.

Journal: Lancet (London, England) 20060211

Title: Downregulation of endothelin-1 by farnesoid X receptor in vascular endothelial cells.

Journal: Circulation research 20060203

Title: A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids.

Journal: Journal of lipid research 20060201

Title: Molecular adsorbent recirculating system (MARS) application in liver failure: clinical and hemodepurative results in 22 patients.

Journal: The International journal of artificial organs 20060201

Title: Micellization of conjugated chenodeoxy- and ursodeoxycholates and solubilization of cholesterol into their micelles: comparison with other four conjugated bile salts species.

Journal: Chemistry and physics of lipids 20060101

Title: Bile acid metabolism in extrahepatic biliary atresia: lithocholic acid in stored dried blood collected at neonatal screening.

Journal: Upsala journal of medical sciences 20060101

Title: Influence of charge and steric bulk in the C-24 region on the interaction of bile acids with human apical sodium-dependent bile acid transporter.

Journal: Molecular pharmaceutics 20060101

Title: Chenodeoxycholic acid reduce bacterial translocation in sepsis.

Journal: Medical hypotheses 20060101

Title: [Effect of thromboxane B2 on morphological features of apoptosis in cultured rat hepatocytes exposed to hepatotropic substances].

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20060101

Title: Synthetic bile acid derivatives induce apoptosis through a c-Jun N-terminal kinase and NF-kappaB-dependent process in human cervical carcinoma cells.

Journal: Cancer letters 20051108

Title: Bile acids reduce SR-BI expression in hepatocytes by a pathway involving FXR/RXR, SHP, and LRH-1.

Journal: Biochemical and biophysical research communications 20051104

Title: Xanthohumol, the chalcone from beer hops (Humulus lupulus L.), is the ligand for farnesoid X receptor and ameliorates lipid and glucose metabolism in KK-A(y) mice.

Journal: Biochemical and biophysical research communications 20051028

Title: Cross-talk between farnesoid-X-receptor (FXR) and peroxisome proliferator-activated receptor gamma contributes to the antifibrotic activity of FXR ligands in rodent models of liver cirrhosis.

Journal: The Journal of pharmacology and experimental therapeutics 20051001

Title: 1H and 13C NMR characterization and stereochemical assignments of bile acids in aqueous media.

Journal: Lipids 20051001

Title: Impaired proximal colonic motor response to rectal mechanical and chemical stimulation in obstructed defecation.

Journal: Diseases of the colon and rectum 20050901

Title: VPAC1 expression is regulated by FXR agonists in the human gallbladder epithelium.

Journal: Hepatology (Baltimore, Md.) 20050901

Title: Downregulation of TACO gene transcription restricts mycobacterial entry/survival within human macrophages.

Journal: FEMS microbiology letters 20050901

Title: Synthetic chenodeoxycholic acid derivatives inhibit glioblastoma multiform tumor growth in vitro and in vivo.

Journal: International journal of oncology 20050901

Title: Cerebrotendinous xanthomatosis: possible higher prevalence than previously recognized.

Journal: Archives of neurology 20050901

Title: Development of stably transfected monolayer overexpressing the human apical sodium-dependent bile acid transporter (hASBT).

Journal: Pharmaceutical research 20050801

Title: Lithocholic acid decreases expression of UGT2B7 in Caco-2 cells: a potential role for a negative farnesoid X receptor response element.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050701

Title: The cell envelope structure and properties of Mycobacterium smegmatis mc(2)155: is there a clue for the unique transformability of the strain?

Journal: Microbiology (Reading, England) 20050601

Title: Protective effects of 6-ethyl chenodeoxycholic acid, a farnesoid X receptor ligand, in estrogen-induced cholestasis.

Journal: The Journal of pharmacology and experimental therapeutics 20050501

Title: Cerebrotendinous xanthomatosis: a treatable ataxia.

Journal: Neurology 20050426

Title: Bile acids induce MUC2 overexpression in human colon carcinoma cells.

Journal: Cancer 20050415

Title: Cytokine regulation of human sterol 12alpha-hydroxylase (CYP8B1) gene.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20050401

Title: Chemical synthesis of 24-beta-D-galactopyranosides of bile acids: a new type of bile acid conjugates in human urine.

Journal: Chemistry and physics of lipids 20050401

Title: Increasing ursodeoxycholic acid in the enterohepatic circulation of pigs through the administration of living bacteria.

Journal: The British journal of nutrition 20050401

Title: Isotopomer spectral analysis of intermediates of cholesterol synthesis in patients with cerebrotendinous xanthomatosis.

Journal: Metabolism: clinical and experimental 20050301

Title: A new drug carrier, Nalpha-deoxycholyl-L: -lysyl-methylester, for enhancing insulin absorption in the intestine.

Journal: Diabetologia 20050301

Title: Bile-induced laryngitis: is there a basis in evidence?

Journal: The Annals of otology, rhinology, and laryngology 20050301

Title: Disrupted coordinate regulation of farnesoid X receptor target genes in a patient with cerebrotendinous xanthomatosis.

Journal: Journal of lipid research 20050201

Title: Bile acid induced gene expression in LT97 colonic adenoma cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050101

Title: Esophageal visceral sensitivity to bile salts in patients with functional heartburn and in healthy control subjects.

Journal: Digestive diseases and sciences 20050101

Title: [Differential approach to detection and treatment of cholelithiasis in outpatient conditions].

Journal: Terapevticheskii arkhiv 20050101

Title: Polymorphism in the coding part of the sterol 12alpha-hydroxylase gene does not explain the marked differences in the ratio of cholic acid and chenodeoxycholic acid in human bile.

Journal: Scandinavian journal of clinical and laboratory investigation 20050101

Title: Inherited cholesterol lipidosis: cerebrotendinous xanthomatosis (van Bogaert Scherer Epstein disease). A clinicopathological study.

Journal: Clinical neuropathology 20050101

Title: Effects of bile acids on proliferation and production of proteinase activity of Uronema marinum (Ciliophora: Scuticociliatida).

Journal: Diseases of aquatic organisms 20041213

Title: Farnesoid X receptor represses hepatic lipase gene expression.

Journal: Journal of lipid research 20041101

Title: The nuclear receptor SHP mediates inhibition of hepatic stellate cells by FXR and protects against liver fibrosis.

Journal: Gastroenterology 20041101

Title: Bile acid reduces the secretion of very low density lipoprotein by repressing microsomal triglyceride transfer protein gene expression mediated by hepatocyte nuclear factor-4.

Journal: The Journal of biological chemistry 20041029

Title: Normalisation of serum cholestanol concentration in a patient with cerebrotendinous xanthomatosis by combined treatment with chenodeoxycholic acid, simvastatin and LDL apheresis.

Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20041001

Title: The nuclear bile acid receptor FXR is activated by PGC-1alpha in a ligand-dependent manner.

Journal: The Biochemical journal 20040915

Title: Bioconversion of 3beta-hydroxy-5-cholenoic acid into chenodeoxycholic acid by rat brain enzyme systems.

Journal: Journal of lipid research 20040901

Title: The farnesoid X receptor: a novel drug target?

Journal: Expert opinion on investigational drugs 20040901

Title: DNA hypomethylation induced by non-genotoxic carcinogens in mouse and rat colon.

Journal: Cancer letters 20040830

Title: Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure-activity relationship of a series of body and side chain modified analogues of chenodeoxycholic acid.

Journal: Journal of medicinal chemistry 20040826

Title: Bile acid-induced negative feedback regulation of the human ileal bile acid transporter.

Journal: Hepatology (Baltimore, Md.) 20040701

Title: [Menthol in the adjuvant treatment of gallbladder stones fragmented by ESWL as an option for reducing doses of urso- and chenodeoxycholic acid].

Journal: Medizinische Klinik (Munich, Germany : 1983) 20040615

Title: Epimerization of chenodeoxycholic acid to ursodeoxycholic acid by Clostridium baratii isolated from human feces.

Journal: FEMS microbiology letters 20040601

Title: Effect of chenodeoxycholic acid on 11beta-hydroxysteroid dehydrogenase in various target tissues.

Journal: Metabolism: clinical and experimental 20040601

Title: Short-step synthesis of chenodiol from stigmasterol.

Journal: Bioscience, biotechnology, and biochemistry 20040601

Title: [Cerebrotendinous xanthomatosis--a treatable metabolic disorder].

Journal: Der Nervenarzt 20040601

Title: Production of prostaglandinE2 via bile acid is enhanced by trypsin and acid in normal human esophageal epithelial cells.

Journal: Life sciences 20040521

Title: The farnesoid X receptor induces very low density lipoprotein receptor gene expression.

Journal: FEBS letters 20040521

Title: Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: the switch between apoptosis and necrosis.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20040501

Title: Hydrophilic 7 beta-hydroxy bile acids, lovastatin, and cholestyramine are ineffective in the treatment of cerebrotendinous xanthomatosis.

Journal: Metabolism: clinical and experimental 20040501

Title: [Studies on mechanism of antiasthmatic and anti-inflammatory actions of CDCA].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040401

Title: The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashion.

Journal: The Journal of biological chemistry 20040305

Title: [Studies on antitussive, antiasthmatic and expectorant action of chenodeoxycholine acid].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20040301

Title: Inhibitory effect of the small heterodimer partner on hepatocyte nuclear factor-4 mediates bile acid-induced repression of the human angiotensinogen gene.

Journal: The Journal of biological chemistry 20040227

Title: Serum bile acids and risk factors for colorectal cancer.

Journal: British journal of cancer 20040209

Title: Increased acyclovir oral bioavailability via a bile acid conjugate.

Journal: Molecular pharmaceutics 20040112

Title: Facile synthesis, aggregation behavior, and cholesterol solubilization ability of avicholic acid.

Journal: Organic letters 20040108

Title: Structure-activity relationship of bile acids and bile acid analogs in regard to FXR activation.

Journal: Journal of lipid research 20040101

Title: 3Alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate as blood-brain barrier permeator.

Journal: Polish journal of pharmacology 20040101

Title: Comparison among fecal secondary bile acid levels, fecal microbiota and Clostridium scindens cell numbers in Japanese.

Journal: Microbiology and immunology 20040101

Title: Enhanced susceptibility of LDL to oxidative modification in a CTX patient:- role of chenodeoxycholic acid in xanthoma formation.

Journal: Journal of atherosclerosis and thrombosis 20040101

Title: T0901317 is a dual LXR/FXR agonist.

Journal: Molecular genetics and metabolism 20040101

Title: Combined treatment with LDL-apheresis, chenodeoxycholic acid and HMG-CoA reductase inhibitor for cerebrotendinous xanthomatosis.

Journal: Journal of the neurological sciences 20031215

Title: In vitro farnesoid X receptor ligand sensor assay using surface plasmon resonance and based on ligand-induced coactivator association.

Journal: The Journal of steroid biochemistry and molecular biology 20031201

Title: Cloning and characterization of the NAD-dependent 7alpha-Hydroxysteroid dehydrogenase from Bacteroides fragilis.

Journal: Current microbiology 20031201

Title: Orphan nuclear receptor Nur77 translocates to mitochondria in the early phase of apoptosis induced by synthetic chenodeoxycholic acid derivatives in human stomach cancer cell line SNU-1.

Journal: Annals of the New York Academy of Sciences 20031201

Title: Micelle formation of sodium chenodeoxycholate and solubilization into the micelles: comparison with other unconjugated bile salts.

Journal: Biochimica et biophysica acta 20031115

Title: Bile acid composition in snake bile juice and toxicity of snake bile acids to rats.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20031101

Title: Metabolic changes in Clostridium absonum ATCC 27555 accompanying induction of epimerization of a primary bile acid.

Journal: Current microbiology 20031101

Title: Steroid ring hydroxylation patterns govern cooperativity in human bile acid binding protein.

Journal: Biochemistry 20031014

Title: Mutations in SRD5B1 (AKR1D1), the gene encoding delta(4)-3-oxosteroid 5beta-reductase, in hepatitis and liver failure in infancy.

Journal: Gut 20031001

Title: Feedback regulation of bile acid synthesis in primary human hepatocytes: evidence that CDCA is the strongest inhibitor.

Journal: Hepatology (Baltimore, Md.) 20031001

Title: Apoptosis and modulation of cell cycle control by synthetic derivatives of ursodeoxycholic acid and chenodeoxycholic acid in human prostate cancer cells.

Journal: Cancer letters 20030925

Title: Cerebrotendinous xanthomatosis: clinical manifestations, diagnostic criteria, pathogenesis, and therapy.

Journal: Journal of child neurology 20030901

Title: Regulation of human sterol 27-hydroxylase gene (CYP27A1) by bile acids and hepatocyte nuclear factor 4alpha (HNF4alpha).

Journal: Gene 20030814

Title: Human kininogen gene is transactivated by the farnesoid X receptor.

Journal: The Journal of biological chemistry 20030801

Title: Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis.

Journal: Genes & development 20030701

Title: Binding mode of 6ECDCA, a potent bile acid agonist of the farnesoid X receptor (FXR).

Journal: Bioorganic & medicinal chemistry letters 20030602

Title: Synergism between nuclear receptors bound to specific hormone response elements of the hepatic control region-1 and the proximal apolipoprotein C-II promoter mediate apolipoprotein C-II gene regulation by bile acids and retinoids.

Journal: The Biochemical journal 20030601

Title: Hydrophilic but not hydrophobic bile acids prevent gallbladder muscle dysfunction in acute cholecystitis.

Journal: Hepatology (Baltimore, Md.) 20030601

Title: Bile acid induces cyclo-oxygenase-2 expression in cultured human pharyngeal cells: a possible mechanism of carcinogenesis in the upper aerodigestive tract by laryngopharyngeal reflux.

Journal: The Laryngoscope 20030601

Title: FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity.

Journal: Gastroenterology 20030601

Title: Influence of ethinyloestradiol propanolsulphonate on serum bile acids in healthy volunteers.

Journal: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030601

Title: Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter.

Journal: The Journal of biological chemistry 20030530

Title: Guggulsterone antagonizes farnesoid X receptor induction of bile salt export pump but activates pregnane X receptor to inhibit cholesterol 7alpha-hydroxylase gene.

Journal: Biochemical and biophysical research communications 20030425

Title: Regression of diaphyseal multiloculated bone cyst in familial steroid dehydrogenase deficiency.

Journal: Journal of pediatric gastroenterology and nutrition 20030401

Title: A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR.

Journal: Molecular cell 20030401

Title: Gum arabic (GA) modifies paracellular water and electrolyte transport in the small intestine.

Journal: Digestive diseases and sciences 20030401

Title: Differentiated thermal crystallization from amorphous chenodeoxycholic acid between the ground specimens derived from the polymorphs.

Journal: International journal of pharmaceutics 20030306

Title: Hepatocyte nuclear factor 1 alpha: a key mediator of the effect of bile acids on gene expression.

Journal: Hepatology (Baltimore, Md.) 20030301

Title: Synthetic chenodeoxycholic acid derivative HS-1200-induced apoptosis of p815 mastocytoma cells is augmented by co-treatment with lactacystin.

Journal: Anti-cancer drugs 20030301

Title: Upregulation of the oncogene c-myc in Barrett's adenocarcinoma: induction of c-myc by acidified bile acid in vitro.

Journal: Gut 20030201

Title: Bile acids induce the expression of the human peroxisome proliferator-activated receptor alpha gene via activation of the farnesoid X receptor.

Journal: Molecular endocrinology (Baltimore, Md.) 20030201

Title: Increase of bile acid production by tacrolimus in the rat liver.

Journal: Transplantation proceedings 20030201

Title: Mitochondrially mediated synergistic cell killing by bile acids.

Journal: Biochimica et biophysica acta 20030120

Title: Influence of breast feeding, and adapted and hydrolyzed formulas on biliary bile acids in newborn guinea pigs.

Journal: Biology of the neonate 20030101

Title: Role of MR imaging in the diagnosis of cerebrotendinous xanthogranulomatosis, case report and review of literature.

Journal: La Radiologia medica 20030101

Title: Cholestanol metabolism, molecular pathology, and nutritional implications.

Journal: Journal of medicinal food 20030101

Title: [Cerebrotendinous xanthomatosis, a treatable metabolic disorder].

Journal: Der Nervenarzt 20021201

Title: Selective inhibition of CYP27A1 and of chenodeoxycholic acid synthesis in cholestatic hamster liver.

Journal: Biochimica et biophysica acta 20021120

Title: Bile acids enhance low density lipoprotein receptor gene expression via a MAPK cascade-mediated stabilization of mRNA.

Journal: The Journal of biological chemistry 20021004

Title: Potential bile acid metabolites. 25. Synthesis and chemical properties of stereoisomeric 3alpha,7alpha,16- and 3alpha,7alpha,15-trihydroxy-5beta-cholan-24-oic acids.

Journal: Chemical & pharmaceutical bulletin 20021001

Title: Mutations in the sterol 27-hydroxylase gene (CYP27A) cause hepatitis of infancy as well as cerebrotendinous xanthomatosis.

Journal: Journal of inherited metabolic disease 20021001

Title: Effect of chenodeoxycholic acid on the toxicity of 5alpha-cyprinol sulfate in rats.

Journal: Toxicology 20020930

Title: Synthesis of [3,4-(13)c(2)]-enriched bile salts as NMR probes of protein-ligand interactions.

Journal: The Journal of organic chemistry 20020920

Title: 6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity.

Journal: Journal of medicinal chemistry 20020815

Title: The amino acid residues asparagine 354 and isoleucine 372 of human farnesoid X receptor confer the receptor with high sensitivity to chenodeoxycholate.

Journal: The Journal of biological chemistry 20020719

Title: Chenodeoxycholic acid and deoxycholic acid inhibit 11 beta-hydroxysteroid dehydrogenase type 2 and cause cortisol-induced transcriptional activation of the mineralocorticoid receptor.

Journal: The Journal of biological chemistry 20020719

Title: Fibrates suppress chenodeoxycholic acid-induced RANTES expression through inhibition of NF-kappaB activation.

Journal: European journal of pharmacology 20020712

Title: Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling.

Journal: The Journal of biological chemistry 20020705

Title: Human organic anion transporting polypeptide 8 promoter is transactivated by the farnesoid X receptor/bile acid receptor.

Journal: Gastroenterology 20020601

Title: A natural product that lowers cholesterol as an antagonist ligand for FXR.

Journal: Science (New York, N.Y.) 20020531

Title: Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters.

Journal: Gene 20020515

Title: A novel primary bile acid in the Shoebill stork and herons and its phylogenetic significance.

Journal: Journal of lipid research 20020501

Title: Immunosuppressive effect of chenodeoxycholic acid on natural killer cell activity in patients with biliary atresia and hepatitis C virus-related liver cirrhosis.

Journal: Digestive diseases and sciences 20020501

Title: Disruption of mitochondrial calcium homeostasis after chronic alpha-naphthylisothiocyanate administration: relevance for cholestasis.

Journal: Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20020501

Title: Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes.

Journal: Hepatology (Baltimore, Md.) 20020401

Title: Cerebrotendinous xanthomatosis: a rare disease with diverse manifestations.

Journal: Archives of neurology 20020401

Title: The proximal colonic motor response to rectal mechanical and chemical stimulation.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20020301

Title: Characterization of rat liver bile acid acyl glucuronosyltransferase.

Journal: Steroids 20020301

Title: Unconjugated bile acids modulate adult and neonatal neutrophil chemotaxis induced in vitro by N-formyl-met-leu-phe-peptide.

Journal: Pediatric research 20020301

Title: Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump.

Journal: Hepatology (Baltimore, Md.) 20020301

Title: The UDCA dosage deficit: a fate shared with CDCA.

Journal: European journal of gastroenterology & hepatology 20020301

Title: MALDI-TOF-MS analysis of droplets prepared in an electrodynamic balance: 'wall-less' sample preparation.

Journal: Analytical chemistry 20020201

Title: Conversion of 7 alpha-hydroxycholesterol to bile acid in human subjects: is there an alternate pathway favoring cholic acid synthesis?

Journal: The Journal of laboratory and clinical medicine 20020201

Title: Induction of cyclooxygenase-2 by tumor promoters in transformed and cytochrome P450 2E1-expressing hepatocytes.

Journal: Carcinogenesis 20020101

Title: Bile salts modulate chronic ethanol-induced hepatotoxicity.

Journal: Alcohol and alcoholism (Oxford, Oxfordshire) 20020101

Title: Effects of bile acids on base hydroxylation in a model of human colonic mucosal DNA.

Journal: Cancer detection and prevention 20020101

Title: Use of dominant negative nuclear receptors to study xenobiotic-inducible gene expression in primary cultured hepatocytes.

Journal: Journal of pharmacological and toxicological methods 20020101

Title: Enhanced expression of the human multidrug resistance protein 3 by bile salt in human enterocytes. A transcriptional control of a plausible bile acid transporter.

Journal: The Journal of biological chemistry 20011214

Title: Antagonism of the actions of peroxisome proliferator-activated receptor-alpha by bile acids.

Journal: The Journal of biological chemistry 20011214

Title: Duodenal reflux induces cyclooxygenase-2 in the esophageal mucosa of rats: evidence for involvement of bile acids.

Journal: Gastroenterology 20011201

Title: Effect of bile acids on absorption of nitrendipine in healthy subjects.

Journal: British journal of clinical pharmacology 20011201

Title: Inducible microsomal prostaglandin E synthase is overexpressed in colorectal adenomas and cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20011201

Title: Anti-inflammatory effects of 5-aminosalicylic acid conjugates with chenodeoxycholic acid and ursodeoxycholic acid on carrageenan-induced colitis in guinea-pigs.

Journal: The Journal of pharmacy and pharmacology 20011201

Title: Bile acids regulate RANTES gene expression through its cognate NF-kappaB binding sites.

Journal: Biochemical and biophysical research communications 20011116

Title: Cerebrotendinous xanthomatosis.

Journal: Neurology 20011113

Title: Reduced activity of 11 beta-hydroxysteroid dehydrogenase in patients with cholestasis.

Journal: The Journal of clinical investigation 20011101

Title: Green tea upregulates the low-density lipoprotein receptor through the sterol-regulated element binding Protein in HepG2 liver cells.

Journal: Journal of agricultural and food chemistry 20011101

Title: Functional analysis of the transcriptional activity of the mouse phospholipid transfer protein gene.

Journal: Biochemical and biophysical research communications 20011005

Title: Effects of bile acids on the humoral immune response: a mechanistic approach.

Journal: Life sciences 20011005

Title: Cerebrotendinous xanthomatosis: 11-year treatment with chenodeoxycholic acid in five patients. An electrophysiological study.

Journal: Journal of the neurological sciences 20010915

Title: Effect of bile acids on formation of azoxymethane-induced aberrant crypt foci in colostomized F344 rat colon.

Journal: Cancer letters 20010828

Title: Cerebrotendinous xanthomatosis.

Journal: Journal of the American Academy of Dermatology 20010801

Title: Cerebrotendinous xanthomatosis presenting as 'chologenic diarrhoea'.

Journal: Acta paediatrica (Oslo, Norway : 1992) 20010701

Title: Protective effect of carvedilol on chenodeoxycholate induction of the permeability transition pore.

Journal: Biochemical pharmacology 20010601

Title: Expression of sterol 12alpha-hydroxylase alters bile acid pool composition in primary rat hepatocytes and in vivo.

Journal: Gastroenterology 20010601

Title: Apoptotic activity of novel bile acid derivatives in human leukemic T cells through the activation of caspases.

Journal: International journal of oncology 20010501

Title: Effects of treatment with deoxycholic acid and chenodeoxycholic acid on the hepatic synthesis of cholesterol and bile acids in healthy subjects.

Journal: Hepatology (Baltimore, Md.) 20010501

Title: Synthetic bile acid derivatives induce nonapoptotic death of human retinal pigment epithelial cells.

Journal: Current eye research 20010501

Title: Enhancement of endothelial nitric oxide production by chenodeoxycholic acids in patients with hepatobiliary diseases.

Journal: Japanese heart journal 20010501

Title: Effects of bile salts and aliphatic ionic surfactants on human lymphocyte proliferation.

Journal: European journal of clinical investigation 20010401

Title: Successful combination therapy--flunarizine, pentoxifylline, and cholestyramine--for spur cell anemia.

Journal: International journal of hematology 20010401

Title: Cloning and expression of a pig liver taurochenodeoxycholic acid 6alpha-hydroxylase (CYP4A21): a novel member of the CYP4A subfamily.

Journal: The Journal of biological chemistry 20010330

Title: Chenodeoxycholic treatment of cerebrotendinous xanthomatosis.

Journal: Neurology 20010313

Title: Ursodeoxycholic acid administration in patients with cholestasis of pregnancy: effects on primary bile acids in babies and mothers.

Journal: Hepatology (Baltimore, Md.) 20010301

Title: Hypocholesterolemic effect of bile acid sulfonate analogs in hamsters.

Journal: Biological & pharmaceutical bulletin 20010301

Title: Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid.

Journal: Journal of hepatology 20010301

Title: [3 beta-Hydroxysteroid-delta 5-oxidoreductase/isomerase deficiency].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301

Title: [3-oxo-delta 4-steroid 5 beta-reductase deficiency].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301

Title: [Cerebrotendinous xanthomatosis].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301

Title: [Other antihyperlipidemic drugs with novel mechanism].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20010301

Title: Novel bile acid derivatives induce apoptosis via a p53-independent pathway in human breast carcinoma cells.

Journal: Cancer letters 20010210

Title: Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria.

Journal: Bioscience reports 20010201

Title: Ursodeoxycholic acid alone or with chenodeoxycholic acid for dissolution of cholesterol gallstones: a randomized multicentre trial. The British-Italian Gallstone Study group.

Journal: Alimentary pharmacology & therapeutics 20010101

Title: [Advances in the diagnosis and treatment of cholelithiasis].

Journal: Terapevticheskii arkhiv 20010101

Title: Cerebrotendinous xanthomatosis in three siblings from a Chinese family.

Journal: Singapore medical journal 20010101

Title: Enzyme immunoassay for conjugated 7alpha-hydroxy-3-oxo-4-cholenoic acid in human urine.

Journal: Journal of immunoassay & immunochemistry 20010101

Title: Suppression of renal disease and mortality in the female NZB x NZW F1 mouse model of systemic lupus erythematosus (SLE) by chenodeoxycholic acid.

Journal: Lupus 20010101

Title: Extracorporeal shock wave lithotripsy of gallstones with oral dissolution. Results in course of ten years in Czech Republic in correlation to indication criteria.

Journal: Sbornik lekarsky 20010101

Title: Characterization of chenodeoxycholic acid as an endogenous antagonist of the G-coupled formyl peptide receptors.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20001201

Title: In the search for specific inhibitors of human 11beta-hydroxysteroid-dehydrogenases (11beta-HSDs): chenodeoxycholic acid selectively inhibits 11beta-HSD-I.

Journal: European journal of endocrinology 20000201

Title: Identification of a nuclear receptor for bile acids.

Journal: Science (New York, N.Y.) 19990521

Title: Bile acids: natural ligands for an orphan nuclear receptor.

Journal: Science (New York, N.Y.) 19990521

Title: Endogenous bile acids are ligands for the nuclear receptor FXR/BAR.

Journal: Molecular cell 19990501

Title: Differential effects of 17alpha-ethinylestradiol on the neutral and acidic pathways of bile salt synthesis in the rat.

Journal: Journal of lipid research 19990101

Title: Induction of the transcription factor AP-1 in cultured human colon adenocarcinoma cells following exposure to bile acids.

Journal: Carcinogenesis 19960301

Title: Cyclosporin A-mediated cholestasis in patients with chronic hepatitis after heart transplantation.

Journal: European journal of gastroenterology & hepatology 19960301

Title: Ursodeoxycholic acid in the Ursidae: biliary bile acids of bears, pandas, and related carnivores.

Journal: Journal of lipid research 19931101

Title: Oral and contact dissolution of gallstones.

Journal: American journal of surgery 19930401

Title: Promotion of hepatocellular foci in female rats by chenodeoxycholic acid.

Journal: Carcinogenesis 19910101

Title: Benign recurrent intrahepatic cholestasis: altered bile acid metabolism.

Journal: Gastroenterology 19890801

Title: [Promoting effect of bile acids on gastric carcinogenesis induced by MNNG in rats].

Journal: Nihon Geka Gakkai zasshi 19890101

Title: Comparative efficacy and side effects of ursodeoxycholic and chenodeoxycholic acids in dissolving gallstones. A double-blind controlled study.

Journal: Gastroenterology 19831201

Title: Early morphologic and enzymatic changes in livers of rats treated with chenodeoxycholic and ursodeoxycholic acids.

Journal: Hepatology (Baltimore, Md.) 19830101

Title: Serum bile acid levels in intrahepatic cholestasis of pregnancy during treatment with phenobarbital or cholestyramine.

Journal: European journal of obstetrics, gynecology, and reproductive biology 19821201

Title: Carcinoma of the gall-bladder in a patient on long-term chenodeoxycholic acid therapy.

Journal: Clinical oncology 19810901

Title: Lack of response to chenodeoxycholic acid in obese and non-obese patients. Role of cholesterol synthesis and possible response to ursodeoxycholic acid.

Journal: Gut 19801201

Title: [Effect of cholestyramine and chenodesoxycholic acid on liver cirrhosis. An experimental study in rats].

Journal: Zeitschrift fur experimentelle Chirurgie 19800401

Title: Hepatic toxicity in the rhesus monkey treated with chenodeoxycholic acid for 6 months: biochemical and ultrastructural studies.

Journal: Gastroenterology 19760101

Title: Effects of clofibrate in primary biliary cirrhosis hypercholesterolemia and gallstones.

Journal: Gastroenterology 19751001

Title: Measurement of bile acid synthesis by 14CO2: the metabolism of propionyl CoA.

Journal: Steroids 19751001

Title: Toxicity of chenodeoxycholic acid in the rhesus monkey.

Journal: Gastroenterology 19750801

Title: Toxicity of chenodeoxycholic acid in the nonhuman primate.

Journal: Surgery 19750601

Title: Medical treatment of gallstones.

Journal: Southern medical journal 19750101

Title: [Effects of diet on bile secretion].

Journal: Acta medica Austriaca 19750101

Title: Farnesoid X receptor protects liver cells from apoptosis induced by serum deprivation in vitro and fasting in vivo.

Journal: Molecular endocrinology (Baltimore, Md.)

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SDS
Tags:2646-38-0 Molecular Formula|2646-38-0 MDL|2646-38-0 SMILES|2646-38-0 Cholan-24-oic acid, 3,7-dihydroxy-, monosodium salt, (3α,5β,7α)-