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26575-95-1,MFCD00867379
Catalog No.:AA002TOG

26575-95-1 | Alisol B 23-acetate

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Purity
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5mg
98% by HPLC
in stock  
$156.00   $109.00
- +
10mg
98% by HPLC
in stock  
$219.00   $153.00
- +
25mg
98% by HPLC
in stock  
$392.00   $274.00
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50mg
98% by HPLC
in stock  
$622.00   $435.00
- +
100mg
98% by HPLC
in stock  
$1,029.00   $720.00
- +
500mg
98% by HPLC
in stock  
$3,179.00   $2,226.00
- +
1000mg
98% by HPLC
in stock  
$5,049.00   $3,534.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA002TOG
Chemical Name:
Alisol B 23-acetate
CAS Number:
26575-95-1
Molecular Formula:
C32H50O5
Molecular Weight:
514.7364
MDL Number:
MFCD00867379
SMILES:
CC(=O)O[C@H]([C@H]1OC1(C)C)C[C@H](C1=C2C[C@H](O)[C@@H]3[C@]([C@]2(CC1)C)(C)CC[C@@H]1[C@]3(C)CCC(=O)C1(C)C)C
Properties
Computed Properties
 
Complexity:
1020  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
9  
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
XLogP3:
5.4  

Literature

Title: Role of RAS/Wnt/β-catenin axis activation in the pathogenesis of podocyte injury and tubulo-interstitial nephropathy.

Journal: Chemico-biological interactions 20170801

Title: Alisol B 23-acetate protects against non-alcoholic steatohepatitis in mice via farnesoid X receptor activation.

Journal: Acta pharmacologica Sinica 20170101

Title: Alisol B 23-acetate protects against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes involved in bile acid homeostasis.

Journal: Toxicology and applied pharmacology 20150315

Title: The rhizomes of Alisma orientale and alisol derivatives inhibit allergic response and experimental atopic dermatitis.

Journal: Biological & pharmaceutical bulletin 20120101

Title: Effects of protostane-type triterpenoids on the 5-HT3A receptor-mediated ion current in Xenopus oocytes.

Journal: Brain research 20100517

Title: [Chemical constituents of Alisma orientalis and their immunosuppressive function].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090401

Title: Effects of methanol extract of Alisma orientale rhizome and its major component, alisol B 23-acetate, on hepatic drug metabolizing enzymes in rats treated with bromobenzene.

Journal: Archives of pharmacal research 20071201

Title: A new triterpene and anti-hepatitis B virus active compounds from Alisma orientalis.

Journal: Planta medica 20060801

Title: Meng Q, et al. Protective effects of alisol B 23-acetate from edible botanical Rhizoma alismatis against carbon tetrachloride-induced hepatotoxicity in mice. Food Funct. 2015 Apr 8;6(4):1241-50.

Title: Meng Q, et al. Alisol B 23-acetate protects against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes involved in bile acid homeostasis. Toxicol Appl Pharmacol. 2015 Mar 15;283(3):178-86.

Title: Meng Q, et al. Alisol B 23-acetate promotes liver regeneration in mice after partial hepatectomy via activating farnesoid X receptor. Biochem Pharmacol. 2014 Nov 15;92(2):289-98.

Title: Meng Q, et al. Protective Effects of Alisol B 23-Acetate Via Farnesoid X Receptor-Mediated Regulation of Transporters and Enzymes in Estrogen-Induced Cholestatic Liver Injury in Mice. Pharm Res. 2015 Jun 4.

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