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2688-77-9,MFCD27978049
Catalog No.:AA00C2QQ

2688-77-9 | laudanosine

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1mg
≥98%
in stock  
$98.00   $68.00
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5mg
≥98%
in stock  
$456.00   $319.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00C2QQ
Chemical Name:
laudanosine
CAS Number:
2688-77-9
Molecular Formula:
C21H27NO4
Molecular Weight:
357.4434
MDL Number:
MFCD27978049
SMILES:
COc1cc(ccc1OC)C[C@@H]1N(C)CCc2c1cc(OC)c(c2)OC
Properties
Computed Properties
 
Complexity:
434  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
5  
Rotatable Bond Count:
6  
XLogP3:
3.7  

Literature

Title: Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism.

Journal: The Journal of biological chemistry 20161104

Title: Characterization of three O-methyltransferases involved in noscapine biosynthesis in opium poppy.

Journal: Plant physiology 20120601

Title: Laudanosine has no effects on respiratory activity but induces non-respiratory excitement activity in isolated brainstem-spinal cord preparation of neonatal rats.

Journal: Advances in experimental medicine and biology 20100101

Title: [Absorption of papaverine, laudanosine and cepharanthine across human intestine by using human Caco-2 cells monolayers model].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080201

Title: Simultaneous determination of atracurium and its metabolite laudanosine in post-mortem fluids by liquid chromatography/multiple-stage mass spectrometry on an ion trap.

Journal: Rapid communications in mass spectrometry : RCM 20070101

Title: Anesthesiologist suicide with atracurium.

Journal: Journal of analytical toxicology 20060301

Title: Chiral separation of norlaudanosoline, laudanosoline, laudanosine, chlorthalidone, and three benzoin derivatives using amino acid based molecular micelles.

Journal: Journal of chromatographic science 20060201

Title: SK channels control the firing pattern of midbrain dopaminergic neurons in vivo.

Journal: The European journal of neuroscience 20051201

Title: The insulin pump as murder weapon: a case report.

Journal: The American journal of forensic medicine and pathology 20040601

Title: Identification and quantitation of six non-depolarizing neuromuscular blocking agents by LC-MS in biological fluids.

Journal: Journal of analytical toxicology 20040301

Title: The possible neuroprotective effect of laudanosine, an atracurium and cisatracurium metabolite.

Journal: Acta anaesthesiologica Scandinavica 20030701

Title: Cerebrospinal fluid concentrations of atracurium, laudanosine and vecuronium following clinical subarachnoid hemorrhage.

Journal: Acta anaesthesiologica Scandinavica 20021101

Title: Methyl-laudanosine: a new pharmacological tool to investigate the function of small-conductance Ca(2+)-activated K(+) channels.

Journal: The Journal of pharmacology and experimental therapeutics 20020901

Title: Pharmacodynamics and atracurium and laudanosine concentrations during a fixed continuous infusion of atracurium in mechanically ventilated patients with acute respiratory distress syndrome.

Journal: Anaesthesia and intensive care 20020801

Title: Laudanosine, an atracurium and cisatracurium metabolite.

Journal: European journal of anaesthesiology 20020701

Title: The pharmacokinetics of cisatracurium in patients with acute respiratory distress syndrome.

Journal: Anesthesia and analgesia 20010801

Title: Blockade and activation of the human neuronal nicotinic acetylcholine receptors by atracurium and laudanosine.

Journal: Anesthesiology 20010401

Title: Pharmacokinetic-pharmacodynamic modeling of atracurium in intensive care patients.

Journal: Journal of clinical pharmacology 20010101

Title: Laudanosine and atracurium concentrations in a patient receiving long-term atracurium infusion.

Journal: Critical care medicine 19980101

Title: Activation of brain acetylcholine receptors by neuromuscular blocking drugs. A possible mechanism of neurotoxicity.

Journal: Anesthesiology 19940501

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Tags:2688-77-9 Molecular Formula|2688-77-9 MDL|2688-77-9 SMILES|2688-77-9 laudanosine