[1]BioorganicandMedicinalChemistry,2004,vol.12,p.309-317
[1]BioorganicandMedicinalChemistry,2004,vol.12,p.309-317
[1]EuropeanJournalofMedicinalChemistry,2009,vol.44,p.2611-2620
[1]EuropeanJournalofMedicinalChemistry,2009,vol.44,p.2611-2620
Title: Gambogic acid sensitizes resistant breast cancer cells to doxorubicin through inhibiting P-glycoprotein and suppressing survivin expression.
Journal: Chemico-biological interactions 20150625
Title: Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20140401
Title: The combination of proteasome inhibitors bortezomib and gambogic acid triggers synergistic cytotoxicity in vitro but not in vivo.
Journal: Toxicology letters 20140130
Title: Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Journal: Bioorganic & medicinal chemistry 20121115
Title: Gambogic acid is a novel anti-cancer agent that inhibits cell proliferation, angiogenesis and metastasis.
Journal: Anti-cancer agents in medicinal chemistry 20121001
Title: Gambogic acid deactivates cytosolic and mitochondrial thioredoxins by covalent binding to the functional domain.
Journal: Journal of natural products 20120622
Title: Design and synthesis of gambogic acid analogs as potent cytotoxic and anti-inflammatory agents.
Journal: Bioorganic & medicinal chemistry letters 20120615
Title: Enhancement of anticancer efficacy of chemotherapeutics by gambogic acid against gastric cancer cells.
Journal: Cancer biotherapy & radiopharmaceuticals 20120601
Title: [Reversal effect of gambogic acid on multidrug resistance of K562/A02 cell line].
Journal: Zhongguo shi yan xue ye xue za zhi 20120401
Title: Synthesis and biological evaluation of novel derivatives of gambogic acid as anti-hepatocellular carcinoma agents.
Journal: Bioorganic & medicinal chemistry letters 20120101
Title: Prenylated caged xanthones: chemistry and biology.
Journal: Pharmaceutical biology 20120101
Title: Poloxamer 407/TPGS mixed micelles for delivery of gambogic acid to breast and multidrug-resistant cancer.
Journal: International journal of nanomedicine 20120101
Title: Gambogic acid-loaded magnetic Fe(3)O(4) nanoparticles inhibit Panc-1 pancreatic cancer cell proliferation and migration by inactivating transcription factor ETS1.
Journal: International journal of nanomedicine 20120101
Title: Synergistic anti-proliferative effects of gambogic acid with docetaxel in gastrointestinal cancer cell lines.
Journal: BMC complementary and alternative medicine 20120101
Title: Induction of programmed erythrocyte death by gambogic acid.
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Title: Gambogic acid inhibits tumor cell adhesion by suppressing integrin β1 and membrane lipid rafts-associated integrin signaling pathway.
Journal: Biochemical pharmacology 20111215
Title: Src regulates Tyr(20) phosphorylation of transferrin receptor-1 and potentiates breast cancer cell survival.
Journal: The Journal of biological chemistry 20111014
Title: [Role of chloride channels in gambogic acid-induced apoptosis of poorly differentiated nasopharyngeal carcinoma cells].
Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110801
Title: Gambogic acid inhibits STAT3 phosphorylation through activation of protein tyrosine phosphatase SHP-1: potential role in proliferation and apoptosis.
Journal: Cancer prevention research (Philadelphia, Pa.) 20110701
Title: Gambogic acid, a natural product inhibitor of Hsp90.
Journal: Journal of natural products 20110527
Title: Absolute configuration of (-)-gambogic acid, an antitumor agent.
Journal: Journal of natural products 20110325
Title: Gambogic acid enhances proteasome inhibitor-induced anticancer activity.
Journal: Cancer letters 20110227
Title: Gambogic acid-induced degradation of mutant p53 is mediated by proteasome and related to CHIP.
Journal: Journal of cellular biochemistry 20110201
Title: Study of the enhanced anticancer efficacy of gambogic acid on Capan-1 pancreatic cancer cells when mediated via magnetic Fe3O4 nanoparticles.
Journal: International journal of nanomedicine 20110101
Title: In vitro screening for angiostatic potential of herbal chemicals.
Journal: Investigative ophthalmology & visual science 20101201
Title: Gambogic acid triggers DNA damage signaling that induces p53/p21(Waf1/CIP1) activation through the ATR-Chk1 pathway.
Journal: Cancer letters 20101001
Title: Gambogic acid induces G0/G1 cell cycle arrest and cell migration inhibition via suppressing PDGF receptor β tyrosine phosphorylation and Rac1 activity in rat aortic smooth muscle cells.
Journal: Journal of atherosclerosis and thrombosis 20100930
Title: Apoptotic activity of caged xanthones from Garcinia hanburyi in cholangiocarcinoma cell lines.
Journal: World journal of gastroenterology 20100514
Title: Identification and quantitative determination of a major circulating metabolite of gambogic acid in human.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100301
Title: Comparison of electron capture-atmospheric pressure chemical ionization and electrospray ionization for the analysis of gambogic acid and its main circulating metabolite in dog plasma.
Journal: European journal of mass spectrometry (Chichester, England) 20100101
Title: [Apoptosis-inducing effect of gambogic acid on K562 cells and its mechanism].
Journal: Zhongguo shi yan xue ye xue za zhi 20091201
Title: Effect of Gambogic acid on the regulation of hERG channel in K562 cells in vitro.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20091001
Title: Gambogic acid induces G0/G1 arrest and apoptosis involving inhibition of SRC-3 and inactivation of Akt pathway in K562 leukemia cells.
Journal: Toxicology 20090803
Title: Reactive oxygen species accumulation contributes to gambogic acid-induced apoptosis in human hepatoma SMMC-7721 cells.
Journal: Toxicology 20090616
Title: GA3, a new gambogic acid derivative, exhibits potent antitumor activities in vitro via apoptosis-involved mechanisms.
Journal: Acta pharmacologica Sinica 20090301
Title: Synergistic effect of 5-fluorouracil with gambogic acid on BGC-823 human gastric carcinoma.
Journal: Toxicology 20090204
Title: Bioassay guided discovery of apoptosis inducers from gamboge by high-speed counter-current chromatography and high-pressure liquid chromatography/electrospray ionization quadrupole time-of-flight mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090201
Title: Gambogic acid induces apoptosis by regulating the expression of Bax and Bcl-2 and enhancing caspase-3 activity in human malignant melanoma A375 cells.
Journal: International journal of dermatology 20090201
Title: Proteomic identification of molecular targets of gambogic acid: role of stathmin in hepatocellular carcinoma.
Journal: Proteomics 20090101
Title: The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma.
Journal: BMC cancer 20090101
Title: Synergistic effect of magnetic nanoparticles of Fe(3)O(4) with gambogic acid on apoptosis of K562 leukemia cells.
Journal: International journal of nanomedicine 20090101
Title: Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells.
Journal: Molecular cancer therapeutics 20081001
Title: Water-soluble gambogic acid PEGylated prodrugs: synthesis, characterization, physicochemical properties and in vitro hydrolysis.
Journal: Die Pharmazie 20081001
Title: [Analysis of xanthones in gamboge by HPLC-PDA-ESI/MS].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20080801
Title: Inhibition of alpha(4) integrin mediated adhesion was involved in the reduction of B16-F10 melanoma cells lung colonization in C57BL/6 mice treated with gambogic acid.
Journal: European journal of pharmacology 20080728
Title: [Effects of gambogic acid on the regulation of nucleoporin Nup88 in HL-60 cells].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20080701
Title: Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins.
Journal: Molecular cancer therapeutics 20080601
Title: Posttranscriptional regulation of the telomerase hTERT by gambogic acid in human gastric carcinoma 823 cells.
Journal: Cancer letters 20080418
Title: Gambogic acid, a potent inhibitor of survivin, reverses docetaxel resistance in gastric cancer cells.
Journal: Cancer letters 20080418
Title: Synthesis of caged 2,3,3a,7a-tetrahydro-3,6-methanobenzofuran-7(6H)-ones: Evaluating the minimum structure for apoptosis induction by gambogic acid.
Journal: Bioorganic & medicinal chemistry 20080415
Title: Gambogic acid induces death inducer-obliterator 1-mediated apoptosis in Jurkat T cells.
Journal: Acta pharmacologica Sinica 20080301
Title: Preparation, physical properties, and stability of gambogic acid-loaded micelles based on chitosan derivatives.
Journal: Drug development and industrial pharmacy 20080101
Title: Gambogic acid inhibits angiogenesis through suppressing vascular endothelial growth factor-induced tyrosine phosphorylation of KDR/Flk-1.
Journal: Cancer letters 20071208
Title: Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway.
Journal: Blood 20071115
Title: Gambogic acid inhibits the catalytic activity of human topoisomerase IIalpha by binding to its ATPase domain.
Journal: Molecular cancer therapeutics 20070901
Title: Effects of gambogic acid on the regulation of nucleoporin Nup88 in U937 cells.
Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20070801
Title: Gambogic acid-induced G2/M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC-823 cells.
Journal: Carcinogenesis 20070301
Title: Determination of gambogic acid in dog plasma by high-performance liquid chromatography for a pharmacokinetic study.
Journal: Biomedical chromatography : BMC 20070301
Title: Determination of gambogic acid in human plasma by liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070201
Title: Preparative separation of gambogic acid and its C-2 epimer using recycling high-speed counter-current chromatography.
Journal: Journal of chromatography. A 20060915
Title: Metabolism and metabolic inhibition of gambogic acid in rat liver microsomes.
Journal: Acta pharmacologica Sinica 20060901
Title: Stability and cytotoxicity of gambogic acid and its derivative, gambogoic acid.
Journal: Biological & pharmaceutical bulletin 20051201
Title: Anticancer effect and apoptosis induction of gambogic acid in human gastric cancer line BGC-823.
Journal: World journal of gastroenterology 20050628
Title: Gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase mRNA expression in the cells.
Journal: Biological & pharmaceutical bulletin 20041101
Title: Zhai D, et al. Gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins. Mol Cancer Ther. 2008 Jun;7(6):1639-46.
Title: Wang LH, et al. Gambogic acid synergistically potentiates cisplatin-induced apoptosis in non-small-cell lung cancer through suppressing NF-κB and MAPK/HO-1 signalling. Br J Cancer. 2014 Jan 21;110(2):341-52.
