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28282-25-9,MFCD00467083
Catalog No.:AA00C3U1

28282-25-9 | Beta-elemonicacid

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Purity
Availability
Price(USD)
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1mg
95%
in stock  
$12.00   $8.00
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5mg
95%
in stock  
$27.00   $19.00
- +
25mg
95%
in stock  
$68.00   $48.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00C3U1
Chemical Name:
Beta-elemonicacid
CAS Number:
28282-25-9
Molecular Formula:
C30H46O3
Molecular Weight:
454.6844
MDL Number:
MFCD00467083
SMILES:
CC(=CCC[C@@H]([C@@H]1CC[C@]2([C@@]1(C)CCC1=C2CC[C@@H]2[C@]1(C)CCC(=O)C2(C)C)C)C(=O)O)C
Properties
Computed Properties
 
Complexity:
904  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
7.2  

Downstream Synthesis Route

[1]Ruzicka;Rey;Spillmann[HelveticaChimicaActa,1942,vol.25,p.1375,1390]Ruzicka;Haeusermann[HelveticaChimicaActa,1942,vol.25,p.439,447]Ruzickaetal.[HelveticaChimicaActa,1932,vol.15,p.681,690]

[1]Ruzicka;Haeusermann[HelveticaChimicaActa,1942,vol.25,p.439,447]

28282-25-9   
25-bromo-3-oxo-tirucallen-(8)-oicacid-(21) 

[1]Mladenovic;Berkes[MonatsheftefurChemie,1939,vol.72,p.417,421][MonatsheftefuerChemie,1936,vol.67,p.36,39]

28282-25-9   
3-hydroxyimino-tirucalla-8,24-dien-21-oicacid 

[1]Ruzickaetal.[HelveticaChimicaActa,1943,vol.26,p.1659,1664]

28282-25-9   
24ξ,25-dibromo-3-oxo-tirucallen-(8)-oicacid-(21) 

[1]Mladenovic;Berkes[MonatsheftefurChemie,1939,vol.72,p.417,421][MonatsheftefuerChemie,1936,vol.67,p.36,39]

Literature

Title: Tirucallic acids are novel pleckstrin homology domain-dependent Akt inhibitors inducing apoptosis in prostate cancer cells.

Journal: Molecular pharmacology 20100301

Title: Stimulation of leukotriene synthesis in intact polymorphonuclear cells by the 5-lipoxygenase inhibitor 3-oxo-tirucallic acid.

Journal: Molecular pharmacology 20010801

Title: Atta-ur-Rahman, et al. Bioactive constituents from Boswellia papyrifera. J Nat Prod. 2005 Feb;68(2):189-93.

Title: Wu TT, et al. β-Elemonic acid inhibits the cell proliferation of human lung adenocarcinoma A549 cells: The roleof MAPK, ROS activation and glutathione depletion. Oncol Rep. 2016 Jan;35(1):227-34.

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SDS
Tags:28282-25-9 Molecular Formula|28282-25-9 MDL|28282-25-9 SMILES|28282-25-9 Beta-elemonicacid