Title: Involvement of estrogen receptor α in pro-pruritic and pro-inflammatory responses in a mouse model of allergic dermatitis.
Journal: Toxicology and applied pharmacology 20180915
Title: Estrogenicity of halogenated bisphenol A: in vitro and in silico investigations.
Journal: Archives of toxicology 20180301
Title: Binding interactions of halogenated bisphenol A with mouse PPARα: In vitro investigation and molecular dynamics simulation.
Journal: Toxicology letters 20180201
Title: Differential Activation of a Mouse Estrogen Receptor β Isoform (mERβ2) with Endocrine-Disrupting Chemicals (EDCs).
Journal: Environmental health perspectives 20170401
Title: Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-negative inflammatory breast cancer cells.
Journal: Carcinogenesis 20170301
Title: Incorporation of a metabolizing system in biodetection assays for endocrine active substances.
Journal: ALTEX 20170101
Title: Development of phenotypic and transcriptional biomarkers to evaluate relative activity of potentially estrogenic chemicals in ovariectomized mice.
Journal: Environmental health perspectives 20150401
Title: Methoxychlor and its metabolite HPTE inhibit cAMP production and expression of estrogen receptors α and β in the rat granulosa cell in vitro.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20150101
Title: Assessment of estrogenic potential of diethyl phthalate in female reproductive system involving both genomic and non-genomic actions.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20141101
Title: Effects of methoxychlor and its metabolite 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane on human and rat 17α-hydroxylase/17,20-lyase activity.
Journal: Toxicology letters 20140321
Title: Endocrine disrupting chemicals promote the growth of ovarian cancer cells via the ER-CXCL12-CXCR4 signaling axis.
Journal: Molecular carcinogenesis 20130901
Title: Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays.
Journal: Chemical research in toxicology 20130617
Title: Endocrine-Disrupting Chemicals (EDCs): In Vitro Mechanism of Estrogenic Activation and Differential Effects on ER Target Genes.
Journal: Environmental health perspectives 20130401
Title: Effects of methoxychlor and its metabolite 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane on 11β-hydroxysteroid dehydrogenase activities in vitro.
Journal: Toxicology letters 20130327
Title: Distinct mechanisms of endocrine disruption of DDT-related pesticides toward estrogen receptor α and estrogen-related receptor γ.
Journal: Environmental toxicology and chemistry 20121101
Title: Estrogen receptor alpha overexpressing mouse antral follicles are sensitive to atresia induced by methoxychlor and its metabolites.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20120601
Title: A comparison of two human cell lines and two rat gonadal cell primary cultures as in vitro screening tools for aromatase modulation.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20120201
Title: Screening estrogenic activities of chemicals or mixtures in vivo using transgenic (cyp19a1b-GFP) zebrafish embryos.
Journal: PloS one 20120101
Title: The methoxychlor metabolite, HPTE, inhibits rat luteal cell progesterone production.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20110701
Title: Effects of methoxychlor and 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane on 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase-3 activities in human and rat testes.
Journal: International journal of andrology 20110401
Title: Increased sensitivity of estrogen receptor alpha overexpressing antral follicles to methoxychlor and its metabolites.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20110401
Title: Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets.
Journal: Toxicology 20110328
Title: Estrogenic activity of bisphenol A and 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane (HPTE) demonstrated in mouse uterine gene profiles.
Journal: Environmental health perspectives 20110101
Title: [Determination of methoxychlor in rabbit serum and its metabolic products with high performance liquid chromatography].
Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20100801
Title: In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project.
Journal: Environmental health perspectives 20100401
Title: Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program.
Journal: Chemical research in toxicology 20100315
Title: Comparison of relative binding affinities to fish and mammalian estrogen receptors: the regulatory implications.
Journal: Toxicology letters 20100215
Title: Effect of the methoxychlor metabolite HPTE on the rat ovarian granulosa cell transcriptome in vitro.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090701
Title: Influence of dietary Coexposure to benzo(a)pyrene on the biotransformation and distribution of 14C-methoxychlor in the channel catfish (Ictalurus punctatus).
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20090401
Title: Ligand structure-dependent activation of estrogen receptor alpha/Sp by estrogens and xenoestrogens.
Journal: The Journal of steroid biochemistry and molecular biology 20080501
Title: Glucuronidation and sulfonation, in vitro, of the major endocrine-active metabolites of methoxychlor in the channel catfish, Ictalurus punctatus, and induction following treatment with 3-methylcholanthrene.
Journal: Aquatic toxicology (Amsterdam, Netherlands) 20080131
Title: Stimulation of transactivation of the largemouth bass estrogen receptors alpha, beta-a, and beta-b by methoxychlor and its mono- and bis-demethylated metabolites in HepG2 cells.
Journal: The Journal of steroid biochemistry and molecular biology 20080101
Title: The methoxychlor metabolite, HPTE, directly inhibits the catalytic activity of cholesterol side-chain cleavage (P450scc) in cultured rat ovarian cells.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20080101
Title: Methoxychlor and its metabolites inhibit growth and induce atresia of baboon antral follicles.
Journal: Toxicologic pathology 20070801
Title: Early postnatal methoxychlor exposure inhibits folliculogenesis and stimulates anti-Mullerian hormone production in the rat ovary.
Journal: The Journal of endocrinology 20061201
Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.
Journal: Journal of molecular graphics & modelling 20061101
Title: The methoxychlor metabolite, 2,2-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane, inhibits steroidogenesis in rat ovarian granulosa cells in vitro.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20061101
Title: Methoxychlor metabolites may cause ovarian toxicity through estrogen-regulated pathways.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20060901
Title: Demethylation of the pesticide methoxychlor in liver and intestine from untreated, methoxychlor-treated, and 3-methylcholanthrene-treated channel catfish (Ictalurus punctatus): evidence for roles of CYP1 and CYP3A family isozymes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20060601
Title: In vivo exposure of young adult male rats to methoxychlor reduces serum testosterone levels and ex vivo Leydig cell testosterone formation and cholesterol side-chain cleavage activity.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20060201
Title: Activation of kinase pathways in MCF-7 cells by 17beta-estradiol and structurally diverse estrogenic compounds.
Journal: The Journal of steroid biochemistry and molecular biology 20060201
Title: Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.
Journal: Journal of medicinal chemistry 20050908
Title: Differential effects of phthalate esters on transcriptional activities via human estrogen receptors alpha and beta, and androgen receptor.
Journal: Toxicology 20050601
Title: Embryonic co-exposure to methoxychlor and Clophen A50 alters sexual behavior in adult male quail.
Journal: Archives of toxicology 20050401
Title: Methoxychlor induces proliferation of the mouse ovarian surface epithelium.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050201
Title: Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20050101
Title: A comparison of in vitro and in vivo EDSTAC test battery results for detecting antiandrogenic activity.
Journal: Toxicology and applied pharmacology 20050101
Title: Estrogen regulation of testicular function.
Journal: Reproductive biology and endocrinology : RB&E 20050101
Title: The reported active metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane, inhibits testosterone formation by cultured Leydig cells from neonatal rats.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20050101
Title: The effects of the reported active metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane, on testosterone formation by cultured Leydig cells from young adult rats.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20041101
Title: Glucuronidation of the oxidative cytochrome P450-mediated phenolic metabolites of the endocrine disruptor pesticide: methoxychlor by human hepatic UDP-glucuronosyl transferases.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040701
Title: Enantioselective recognition of mono-demethylated methoxychlor metabolites by the estrogen receptor.
Journal: Chemosphere 20040201
Title: Aryl hydrocarbon receptor-mediated inhibition of LNCaP prostate cancer cell growth and hormone-induced transactivation.
Journal: The Journal of steroid biochemistry and molecular biology 20040101
Title: Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor.
Journal: Chemical research in toxicology 20031001
Title: Effects of exogenous estrogenic agents on pubertal growth and reproductive system maturation in female rhesus monkeys.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030701
Title: Enantioselective metabolism of the endocrine disruptor pesticide methoxychlor by human cytochromes P450 (P450s): major differences in selective enantiomer formation by various P450 isoforms.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20021201
Title: Problems for risk assessment of endocrine-active estrogenic compounds.
Journal: Environmental health perspectives 20021201
Title: Development of two androgen receptor assays using adenoviral transduction of MMTV-luc reporter and/or hAR for endocrine screening.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020301
Title: Combined effects of dietary phytoestrogen and synthetic endocrine-active compound on reproductive development in Sprague-Dawley rats: genistein and methoxychlor.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020301
Title: Methoxychlor stimulates the mouse lactoferrin gene promoter through a GC-rich element.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20020101
Title: Differential gene expression in response to methoxychlor and estradiol through ERalpha, ERbeta, and AR in reproductive tissues of female mice.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20010901
Title: Differential activation of wild-type and variant forms of estrogen receptor alpha by synthetic and natural estrogenic compounds using a promoter containing three estrogen-responsive elements.
Journal: The Journal of steroid biochemistry and molecular biology 20010701
Title: Mechanism of induction of cytochrome p450 enzymes by the proestrogenic endocrine disruptor pesticide-methoxychlor: interactions of methoxychlor metabolites with the constitutive androstane receptor system.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010601
Title: Identification of selected hormonally active agents and animal mammary carcinogens in commercial and residential air and dust samples.
Journal: Journal of the Air & Waste Management Association (1995) 20010401
Title: Cell response endpoints enhance sensitivity of the immature mouse uterotropic assay.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20010101
Title: Actions of the endocrine disruptor methoxychlor and its estrogenic metabolite on in vitro embryonic rat seminiferous cord formation and perinatal testis growth.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20010101
Title: Toxicology of environmental estrogens.
Journal: Reproduction, fertility, and development 20010101
Title: Differential estrogen receptor binding of estrogenic substances: a species comparison.
Journal: The Journal of steroid biochemistry and molecular biology 20001115
Title: Interaction of methoxychlor and related compounds with estrogen receptor alpha and beta, and androgen receptor: structure-activity studies.
Journal: Molecular pharmacology 20001001
Title: Activation of a uterine insulin-like growth factor I signaling pathway by clinical and environmental estrogens: requirement of estrogen receptor-alpha.
Journal: Endocrinology 20000901
Title: Estrogenic effects of organochlorine pesticides on uterine leiomyoma cells in vitro.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20000401
Title: A metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1, 1-trichloroethane, reduces testosterone biosynthesis in rat leydig cells through suppression of steady-state messenger ribonucleic acid levels of the cholesterol side-chain cleavage enzyme.
Journal: Biology of reproduction 20000301
Title: Differential interaction of the methoxychlor metabolite 2,2-bis-(p-hydroxyphenyl)-1,1,1-trichloroethane with estrogen receptors alpha and beta.
Journal: Endocrinology 19991201
Title: Estrogen directly respresses gonadotropin-releasing hormone (GnRH) gene expression in estrogen receptor-alpha (ERalpha)- and ERbeta-expressing GT1-7 GnRH neurons.
Journal: Endocrinology 19991101
Title: Signalling by CXC-chemokine receptors 1 and 2 expressed in CHO cells: a comparison of calcium mobilization, inhibition of adenylyl cyclase and stimulation of GTPgammaS binding induced by IL-8 and GROalpha.
Journal: British journal of pharmacology 19990201
Title: Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells.
Journal: Toxicology and applied pharmacology 19980701
Title: Role of hepatic monooxygenases in generating estrogenic metabolites from methoxychlor and from its identified contaminants.
Journal: Molecular pharmacology 19850101
