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29782-68-1,MFCD09970974
Catalog No.:AA00BE2K

29782-68-1 | Silydianin

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20mg
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$415.00   $290.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00BE2K
Chemical Name:
Silydianin
CAS Number:
29782-68-1
Molecular Formula:
C25H22O10
Molecular Weight:
482.4362
MDL Number:
MFCD09970974
SMILES:
COc1cc(ccc1O)[C@@H]1[C@H]2CO[C@@]3([C@H]2C(=C[C@H]1C3=O)[C@H]1Oc2cc(O)cc(c2C(=O)[C@@H]1O)O)O
Properties
Computed Properties
 
Complexity:
935  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
7  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
10  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
3  
XLogP3:
0.8  

Literature

Title: Influence of exogenous salicylic acid on flavonolignans and lipoxygenase activity in the hairy root cultures of Silybum marianum.

Journal: Cell biology international 20090901

Title: Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells.

Journal: International journal of cancer 20080701

Title: Synchronized and sustained release of multiple components in silymarin from erodible glyceryl monostearate matrix system.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070501

Title: Separation and characterization of silybin, isosilybin, silydianin and silychristin in milk thistle extract by liquid chromatography-electrospray tandem mass spectrometry.

Journal: Journal of chromatography. A 20060526

Title: Effect of silybin and its congeners on human liver microsomal cytochrome P450 activities.

Journal: Phytotherapy research : PTR 20021101

Title: Vostálová J, et al. Skin Protective Activity of Silymarin and its Flavonolignans. Molecules. 2019 Mar 14;24(6).

Title: Qin N, et al. Identification of flavonolignans from Silybum marianum seeds as allosteric protein tyrosine phosphatase 1B inhibitors. J Enzyme Inhib Med Chem. 2018 Dec;33(1):1283-1291.

Title: Zielińska-Przyjemska M, et al. An in vitro study of the protective effect of the flavonoid silydianin against reactive oxygen species. Phytother Res. 2006 Feb;20(2):115-9.

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