Home Amines 29854-14-6
29854-14-6,MFCD00792880
Catalog No.:AA007K18

29854-14-6 | N-Desmethyl Clomipramine Hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
≥98%
in stock  
$100.00   $70.00
- +
25mg
98%
in stock  
$411.00   $288.00
- +
50mg
98%
in stock  
$613.00   $429.00
- +
100mg
98%
in stock  
$932.00   $653.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA007K18
Chemical Name:
N-Desmethyl Clomipramine Hydrochloride
CAS Number:
29854-14-6
Molecular Formula:
C18H22Cl2N2
Molecular Weight:
337.2867
MDL Number:
MFCD00792880
SMILES:
CNCCCN1c2ccccc2CCc2c1cc(Cl)cc2.Cl
Properties
Computed Properties
 
Complexity:
322  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  

Literature

Title: NET occupancy by clomipramine and its active metabolite, desmethylclomipramine, in non-human primates in vivo.

Journal: Psychopharmacology 20110701

Title: Regional distribution of clomipramine and desmethylclomipramine in rat brain and peripheral organs on chronic clomipramine administration.

Journal: Journal of psychopharmacology (Oxford, England) 20100801

Title: Desmethylclomipramine induces the accumulation of autophagy markers by blocking autophagic flux.

Journal: Journal of cell science 20090915

Title: Pharmacokinetics of clomipramine and desmethylclomipramine after single-dose intravenous and oral administrations in cats.

Journal: Journal of veterinary pharmacology and therapeutics 20060801

Title: Placental passage of tricyclic antidepressants.

Journal: Biological psychiatry 20060201

Title: Simultaneous analysis of clozapine, clomipramine and their metabolites by reversed-phase liquid chromatography.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20010401

Title: Delirious episodes induced by intravenous administration of clomipramine associated with an acute increase in its plasma concentrations.

Journal: Psychiatry and clinical neurosciences 20001201

Title: Myoclonic movements as a side-effect of treatment with therapeutic doses of clomipramine.

Journal: International clinical psychopharmacology 19871001

Title: Neonatal convulsions caused by withdrawal from maternal clomipramine.

Journal: British medical journal (Clinical research ed.) 19820619

Title: Sioufi A, et al. Simultaneous determination of clomipramine and its N-desmethyl metabolite in human whole blood by capillary gas chromatography with mass-selective detection. J Chromatogr. 1988 Jun 24;428(1):71-80.

Title: Härtter S, et al. Non-competitive inhibition of clomipramine N-demethylation by fluvoxamine. Psychopharmacology (Berl). 1995 Jan;117(2):149-53.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:29854-14-6 Molecular Formula|29854-14-6 MDL|29854-14-6 SMILES|29854-14-6 N-Desmethyl Clomipramine Hydrochloride