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3059-97-0,MFCD00800497
Catalog No.:AA0030K8

3059-97-0 | (R)-(-)-2-Amino-2-methylbutanoic acid

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100mg
95%
in stock  
$17.00   $12.00
- +
250mg
97%
in stock  
$24.00   $17.00
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1g
97%
in stock  
$71.00   $50.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0030K8
Chemical Name:
(R)-(-)-2-Amino-2-methylbutanoic acid
CAS Number:
3059-97-0
Molecular Formula:
C5H11NO2
Molecular Weight:
117.1463
MDL Number:
MFCD00800497
SMILES:
C[C@](C(=O)O)(CC)N
Properties
Properties
 
Form:
Solid  
MP:
276-278°C  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
103  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
-2.3  

Literature

Title: 20-Residue and 11-residue peptaibols from the fungus Trichoderma longibrachiatum are synergistic in forming Na+/K+ -permeable channels and adverse action towards mammalian cells.

Journal: The FEBS journal 20121101

Title: GABA(B) receptor-mediated selective peripheral analgesia by the non-proteinogenic amino acid, isovaline.

Journal: Neuroscience 20120628

Title: R-Isovaline: a subtype-specific agonist at GABA(B)-receptors?

Journal: Neuroscience 20120110

Title: Photostability of Iiovaline and its precursor 5-Ethyl-5- methylhydantoin exposed to simulated space radiations.

Journal: International journal of molecular sciences 20120101

Title: Establishment of stable cell lines with high expression of heterodimers of human 4F2hc and human amino acid transporter LAT1 or LAT2 and delineation of their differential interaction with α-alkyl moieties.

Journal: Journal of pharmacological sciences 20120101

Title: Isovaline, a rare amino acid, has anticonvulsant properties in two in vitro hippocampal seizure models by increasing interneuronal activity.

Journal: Epilepsia 20111101

Title: Distribution and stable isotopic composition of amino acids from fungal peptaibiotics: assessing the potential for meteoritic contamination.

Journal: Astrobiology 20110301

Title: Extended high circular polarization in the Orion massive star forming region: implications for the origin of homochirality in the solar system.

Journal: Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20100601

Title: Configurational assignment of D- and L-isovalines in intact, natural, and synthetic peptides by 2D-NMR spectroscopy.

Journal: Chemistry & biodiversity 20100601

Title: Analgesic properties of the novel amino acid, isovaline.

Journal: Anesthesia and analgesia 20100401

Title: (S)-alpha-methyl,alpha-amino acids: a new stereocontrolled synthesis.

Journal: Amino acids 20100301

Title: Exploring the membrane mechanism of the bioactive peptaibol ampullosporin a using lipid monolayers and supported biomimetic membranes.

Journal: Journal of biophysics (Hindawi Publishing Corporation : Online) 20100101

Title: Isovaline causes inhibition by increasing potassium conductance in thalamic neurons.

Journal: Neuroscience 20091215

Title: Abstracts of the 2008 ISSOL Meeting. August 24-29, 2008. Florence, Italy.

Journal: Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20090801

Title: On-line sample stacking of peptides in capillary electrophoresis for the study of prebiotic reactions between alpha,alpha-dialkylated amino acids and amino acid N-carboxyanhydrides.

Journal: Journal of chromatography. A 20090724

Title: Chirality emergence in thin solid films of amino acids by polarized light from synchrotron radiation and free electron laser.

Journal: International journal of molecular sciences 20090701

Title: Aib and iva in the biosphere: neither rare nor necessarily extraterrestrial.

Journal: Chemistry & biodiversity 20090101

Title: Studies on the selective trifluoroacetolytic scission of native peptaibols and model peptides using HPLC and ESI-CID-MS.

Journal: Chemistry & biodiversity 20081101

Title: Peptaibiomics: towards a myriad of bioactive peptides containing C(alpha)-dialkylamino acids?

Journal: Chemistry & biodiversity 20080901

Title: Peptaibiomics: Screening for polypeptide antibiotics (peptaibiotics) from plant-protective Trichoderma species.

Journal: Chemistry & biodiversity 20060601

Title: Structure determination of neoefrapeptins A to N: peptides with insecticidal activity produced by the fungus Geotrichum candidum.

Journal: The Journal of antibiotics 20060501

Title: Prebiotic amino acids as asymmetric catalysts.

Journal: Science (New York, N.Y.) 20040220

Title: A simple and rapid enzymatic assay for the branched-chain alpha-ketoacid dehydrogenase complex using high-performance liquid chromatography.

Journal: Journal of inherited metabolic disease 20040101

Title: Antibodies directed against L and D isovaline using a chemical derivatizing reagent for the measurement of their enantiomeric ratio in extraterrestrial samples: first step-production and characterization of antibodies.

Journal: Chirality 20020601

Title: Replacements of amino acid residues at subsites and their effects on the catalytic properties of Rhizomucor pusillus pepsin, an aspartic proteinase from Rhizomucor pusillus.

Journal: Journal of biochemistry 20010501

Title: Syntheses and properties of zinc and calcium complexes of valinate and isovalinate: metal alpha-amino acidates as possible constituents of the early Earth's chemical inventory.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20010302

Title: Cephaibols, new peptaibol antibiotics with anthelmintic properties from Acremonium tubakii DSM 12774.

Journal: The Journal of antibiotics 20010301

Title: Survival of amino acids in micrometeorites during atmospheric entry.

Journal: Astrobiology 20010101

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