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3066-84-0,MFCD00055976
Catalog No.:AA0030PQ

3066-84-0 | 8-Bromoguanine

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100mg
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$61.00   $43.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0030PQ
Chemical Name:
8-Bromoguanine
CAS Number:
3066-84-0
Molecular Formula:
C5H4BrN5O
Molecular Weight:
230.0222
MDL Number:
MFCD00055976
SMILES:
Brc1[nH]c2c(n1)c(=O)[nH]c(n2)N
NSC Number:
7845
Properties
Computed Properties
 
Complexity:
254  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  

Downstream Synthesis Route

[1]TetrahedronLetters,1994,vol.35,p.4989-4990

824390-04-7    3066-84-0   
2-amino-8-(4-2-trifluoromethyl-phenoxy-piperidin-1-yl)-1,9-dihydro-6H-purin-6-one 

[1]Patent:WO2007/56846,2007,A1.Locationinpatent:Page/Pagecolumn44-45

3066-84-0   
C19H11ClFN7OS 

[1]EuropeanJournalofPharmaceuticsandBiopharmaceutics,2018,vol.126,p.89-94

3066-84-0   
C19H10Cl2FN7OS 

[1]EuropeanJournalofPharmaceuticsandBiopharmaceutics,2018,vol.126,p.89-94

[1]EuropeanJournalofPharmaceuticsandBiopharmaceutics,2018,vol.126,p.89-94

Literature

Title: Effects of site-specific guanine C8-modifications on an intramolecular DNA G-quadruplex.

Journal: Biophysical journal 20111019

Title: RNA internal loops with tandem AG pairs: the structure of the 5'GAGU/3'UGAG loop can be dramatically different from others, including 5'AAGU/3'UGAA.

Journal: Biochemistry 20100713

Title: A study of the interactions that stabilize DNA frayed wires.

Journal: Biophysical chemistry 20100401

Title: Orientation of ends of G-quadruplex structure investigated with end-extended oligonucleotides.

Journal: Nucleic acids symposium series (2004) 20080101

Title: Kinetic conformational analysis of human 8-oxoguanine-DNA glycosylase.

Journal: The Journal of biological chemistry 20070112

Title: Tautomerism in the guanyl radical.

Journal: Journal of the American Chemical Society 20061025

Title: Chemical radiation studies of 8-bromo-2'-deoxyinosine and 8-bromoinosine in aqueous solutions.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20061010

Title: The new models of the human telomere d[AGGG(TTAGGG)3] in K+ solution.

Journal: Bioorganic & medicinal chemistry 20060815

Title: The new models of the human telomere DNA in K+ solution revealed by NMR analysis assisted by the incorporation of 8-bromoguanines.

Journal: Nucleic acids symposium series (2004) 20060101

Title: Excess electron transfer in G-quadruplex.

Journal: Chemical communications (Cambridge, England) 20040807

Title: Effects of an 8-bromodeoxyguanosine incorporation on the parallel quadruplex structure [d(TGGGT)]4.

Journal: Organic & biomolecular chemistry 20040207

Title: Flipping duplex DNA inside out: a double base-flipping reaction mechanism by Escherichia coli MutY adenine glycosylase.

Journal: The Journal of biological chemistry 20020607

Title: An ab initio study of electronic structure and spectra of 8-bromoguanine: a comparative study with guanine.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20011001

Title: GTP cyclohydrolase I feedback regulatory protein-dependent and -independent inhibitors of GTP cyclohydrolase I.

Journal: Archives of biochemistry and biophysics 20010401

Title: Synthesis and properties of oligonucleotides containing 8-bromo-2'-deoxyguanosine.

Journal: Nucleosides, nucleotides & nucleic acids 20010301

Title: Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii.

Journal: Biochemical pharmacology 19951109

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