Home Bromides 13389-03-2
13389-03-2,MFCD01630971
Catalog No.:AA00HT00

13389-03-2 | 8-Bromo-2'-deoxyguanosine

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Purity
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100mg
98%
in stock  
$9.00   $7.00
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250mg
98%
in stock  
$22.00   $15.00
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1g
98%
in stock  
$33.00   $23.00
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5g
98%
in stock  
$121.00   $85.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00HT00
Chemical Name:
8-Bromo-2'-deoxyguanosine
CAS Number:
13389-03-2
Molecular Formula:
C10H12BrN5O4
Molecular Weight:
346.1374
MDL Number:
MFCD01630971
SMILES:
OC[C@H]1O[C@H](C[C@@H]1O)n1c(Br)nc2c1nc(N)[nH]c2=O
Properties
Computed Properties
 
Complexity:
449  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
2  
XLogP3:
-0.7  

Downstream Synthesis Route

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[2]Gannett;Sura[SyntheticCommunications,1993,vol.23,#11,p.1611-1615]

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[1]Nampalli,Satyam;Kumar,Shiv[BioorganicandMedicinalChemistryLetters,2000,vol.10,#15,p.1677-1679]

[2]Zheng,Yiying;Haratipour,Pouya;Kashemirov,BorisA.;McKenna,CharlesE.[TetrahedronLetters,2021,vol.67]

[3]Lin;Cheng;Ishiguro;Sartorelli[JournalofMedicinalChemistry,1985,vol.28,#9,p.1194-1198]

[4]Kannan,Arunkumar;Burrows,CynthiaJ.[JournalofOrganicChemistry,2011,vol.76,#2,p.720-723]

[1]TetrahedronLetters,1994,vol.35,p.4989-4990

[1]Locationinpatent:schemeortableMatsumoto,Katsuhiko;Takahashi,Naoya;Suzuki,Azusa;Morii,Takashi;Saito,Yoshio;Saito,Isao[BioorganicandMedicinalChemistryLetters,2011,vol.21,#4,p.1275-1278]

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Literature

Title: Direct detection of thrombin binding to 8-bromodeoxyguanosine-modified aptamer: effects of modification on affinity and kinetics.

Journal: Journal of nucleic acids 20110101

Title: Chemical and immunochemical detection of 8-halogenated deoxyguanosines at early stage inflammation.

Journal: The Journal of biological chemistry 20100319

Title: A general synthesis of C8-arylpurine phosphoramidites.

Journal: Molecules (Basel, Switzerland) 20090902

Title: Biophysical properties of quadruplexes containing two or three 8-bromodeoxyguanosine residues.

Journal: Nucleosides, nucleotides & nucleic acids 20070101

Title: Chemical synthesis of 2'-deoxyguanosine-C8 adducts with heterocyclic amines: an application to synthesis of oligonucleotides site-specifically adducted with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

Journal: Chemical research in toxicology 20060601

Title: Effects of an 8-bromodeoxyguanosine incorporation on the parallel quadruplex structure [d(TGGGT)]4.

Journal: Organic & biomolecular chemistry 20040207

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Tags:13389-03-2 Molecular Formula|13389-03-2 MDL|13389-03-2 SMILES|13389-03-2 8-Bromo-2'-deoxyguanosine