Home Other Building Blocks 314728-85-3
314728-85-3,MFCD04112755
Catalog No.:AA007J2K

314728-85-3 | Sunifiram

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$7.00   $5.00
- +
5g
98%
in stock  
$15.00   $11.00
- +
25g
98%
in stock  
$48.00   $34.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA007J2K
Chemical Name:
Sunifiram
CAS Number:
314728-85-3
Molecular Formula:
C14H18N2O2
Molecular Weight:
246.3049
MDL Number:
MFCD04112755
SMILES:
CCC(=O)N1CCN(CC1)C(=O)c1ccccc1
Properties
Computed Properties
 
Complexity:
303  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
1.1  

Literature

Title: Influence of ring size on the cognition-enhancing activity of DM235 and MN19, two potent nootropic drugs.

Journal: Bioorganic & medicinal chemistry letters 20120301

Title: Design, synthesis and nootropic activity of new analogues of sunifiram and sapunifiram, two potent cognition-enhancers.

Journal: Bioorganic & medicinal chemistry 20091101

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Selective phosphodiesterase inhibitors: a promising target for cognition enhancement.

Journal: Psychopharmacology 20090101

Title: Design, synthesis and preliminary pharmacological evaluation of new analogues of DM232 (unifiram) and DM235 (sunifiram) as cognition modulators.

Journal: Bioorganic & medicinal chemistry 20081201

Title: Design, synthesis and preliminary pharmacological evaluation of new piperidine and piperazine derivatives as cognition-enhancers.

Journal: Bioorganic & medicinal chemistry 20080201

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Pharmacological characterization of DM232 (unifiram) and DM235 (sunifiram), new potent cognition enhancers.

Journal: CNS drug reviews 20060101

Title: Structure-activity relationship studies on unifiram (DM232) and sunifiram (DM235), two novel and potent cognition enhancing drugs.

Journal: Bioorganic & medicinal chemistry 20040102

Title: AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram).

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20031201

Title: 4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs.

Journal: Bioorganic & medicinal chemistry letters 20030721

Title: DM235 (sunifiram): a novel nootropic with potential as a cognitive enhancer.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20020601

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Galeotti N, et al. AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram). Naunyn Schmiedebergs Arch Pharmacol. 2003 Dec;368(6):538-45.

Title: Moriguchi S, et al. Novel nootropic drug sunifiram enhances hippocampal synaptic efficacy via glycine-binding site of N-methyl-D-aspartate receptor. Hippocampus. 2013 Jun 3.

Title: Moriguchi S, et al. Novel nootropic drug sunifiram improves cognitive deficits via CaM kinase II and protein kinase C activation in olfactory bulbectomized mice. Behav Brain Res. 2013 Apr 1;242:150-7.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:314728-85-3 Molecular Formula|314728-85-3 MDL|314728-85-3 SMILES|314728-85-3 Sunifiram